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JOURNAL ARTICLE
Christel Barker Jensen, Uffe Vest Schneider, Tina Vasehus Madsen, Xiaohui Chen Nielsen, Chih Man German Ma, Jette Krogh Severinsen, Anne Mette Hoegh, Amanda Bolt Botnen, Ramona Trebbien, Jan Gorm Lisby
BACKGROUND: Rapid and accurate detection of viral respiratory infections is important for infection control measures. This study compares the analytical and clinical performance of the Xpert® Xpress CoV-2/Flu/RSV plus test ("Xpert", Cepheid) and the STANDARD™ M10 Flu/RSV/SARS-CoV-2 test ("M10", SD Biosensor). Both tests are quadruplex RT-PCR assays for rapid diagnosis of SARS-CoV-2, influenza A/B and RSV. STUDY DESIGN: Analytical sensitivities were determined by limit of detection for SARS-CoV-2, influenza A, influenza B and RSV, respectively...
April 16, 2024: Journal of Clinical Virology
#2
JOURNAL ARTICLE
Rebecca L Smith, Thomas Bannard, Jessica McDaniel, Fazil Aliev, Austin Brown, Erica Holliday, Noel Vest, Waltrina DeFrantz-Dufor, Danielle M Dick
The goals of the present study were to describe the development of the first national longitudinal study of collegiate recovery programs (CRP) students; provide an updated characterization of CRP students' demographics, past problem severity, and current recovery-related functioning; and examine the perceived impact of COVID-19 on CRP students' recovery. Universities and community colleges with CRPs across the United States and Ontario, Canada, were invited to partner on this project. Launched in fall 2020, three cohorts of participants were recruited...
2024: Addiction Research & Theory
#3
JOURNAL ARTICLE
Marco Luigetti, Dianna Quan, John L Berk, Isabel Conceição, Yohei Misumi, Chi-Chao Chao, Shaun Bender, Emre Aldinc, John Vest, David Adams
INTRODUCTION: Hereditary transthyretin (ATTRv, v for variant) amyloidosis is a rare, progressive, fatal disease with multisystem manifestations, caused by pathogenic variants in the transthyretin (TTR) gene. Vutrisiran, an RNA interference therapeutic that results in rapid TTR knockdown, improved neuropathy and quality of life (QOL) versus external placebo in patients with ATTRv amyloidosis with polyneuropathy in the phase 3 HELIOS-A study (NCT03759379). This post hoc analysis evaluates the impact of baseline neuropathy severity on response to vutrisiran treatment...
March 21, 2024: Neurology and Therapy
#4
JOURNAL ARTICLE
Luke O Smith, Michael T Vest, Alisha J Rovner, Richard J Caplan, Jillian C Trabulsi, Juhie B Patel, Sarah W Meng, Mary Shapero, Carrie P Earthman
BACKGROUND: Muscle assessment is an important component of nutrition assessment. The Global Leadership Initiative on Malnutrition (GLIM) consortium recently underscored the need for more objective muscle assessment methods in clinical settings. Various assessment techniques are available; however, many have limitations in clinical populations. Computed tomography (CT) scans, obtained for diagnostic reasons, could serve multiple purposes, including muscle measurement for nutrition assessment...
February 23, 2024: JPEN. Journal of Parenteral and Enteral Nutrition
#5
JOURNAL ARTICLE
Noel Vest, Justin S Bell, Alexa Nieder, Rebecca Smith, Thomas Bannard, Sarah Tragesser, Patrick Hibbard, Danielle M Dick
This study examines the association of criminal legal system involvement and age with substance use and academic related outcomes among students involved in collegiate recovery programs in the US. We examined 435 students in collegiate recovery using a national survey of college students. We computed differences between non-system-involved, system-involved with no incarceration history, and formerly incarcerated participants on relevant substance use and recovery-related outcomes. The results provide evidence that there are significant differences between those system-involved and those who are not...
February 13, 2024: Drug and Alcohol Dependence
#6
JOURNAL ARTICLE
Miriam Gutiérrez-Fernández-Calvillo, Miguel Ángel Cámara-Vázquez, Ismael Hernández-Romero, María S Guillem, Andreu M Climent, Carlos Fambuena-Santos, Óscar Barquero-Pérez
BACKGROUND AND OBJECTIVE: Atrial Fibrillation (AF) is a supraventricular tachyarrhythmia that can lead to thromboembolism, hearlt failure, ischemic stroke, and a decreased quality of life. Characterizing the locations where the mechanisms of AF are initialized and maintained is key to accomplishing an effective ablation of the targets, hence restoring sinus rhythm. Many methods have been investigated to locate such targets in a non-invasive way, such as Electrocardiographic Imaging, which enables an on-invasive and panoramic characterization of cardiac electrical activity using recording Body Surface Potentials (BSP) and a torso model of the patient...
February 1, 2024: Computer Methods and Programs in Biomedicine
#7
JOURNAL ARTICLE
Lowell Leow, John Kit Chung Tam, Poh Pei Kee, Amanda Zain
BACKGROUND: Climate change is the greatest threat to human health. Cardiothoracic patients suffer direct consequences from poor environmental health and we have a vested interest to address this in our practice. As leaders of complex high-end surgery, we are uniquely positioned to effect practical and immediate changes to significantly pare down emissions within the operating theatre, outside the operating theatre and beyond the confines of the hospital. METHODS: We aim to spotlight this pressing issue, take stock of our current efforts, and encourage fellow specialists to drive this agenda...
February 12, 2024: ANZ Journal of Surgery
#8
JOURNAL ARTICLE
Venke Torland, Øyvind Thomassen, Øyvind Østerås
BACKGROUND: Kiteboarding (kitesurfing on water and snowkiting) is a fairly new sport and is defined as a high-risk sport. The injury rate has been reported to be between 6 and 9 per 1000 h. The aim of the study was to identify and describe kiteboarding-related injuries in Norway over a five-year period. METHODS: We used "snowball sampling" to identify kiteboarding accidents in a retrospective study. In addition, we conducted structural searches in the National Air Ambulance Service and Search and Rescue Helicopter patient record databases...
January 22, 2024: BMC Sports Science, Medicine and Rehabilitation
#9
JOURNAL ARTICLE
Marinus De Kleuver
Patients with spinal deformities, both adolescents and adults, often experience pulmonary symptoms such as shortness of breath during physical exertion and reduced exercise tolerance. These symptoms significantly affect their daily functioning, and recent research by Van Kempen et al. (2022) involving 8,723 AIS patients found that declines in pulmonary function tests (PFTs) were linked to the severity of their spinal deformities.However, these clinically relevant pulmonary symptoms are not routinely monitored, which could have health implications as patients age, given the gradual deterioration of pulmonary function associated with the severity of their spinal deformities...
2023: Keio Journal of Medicine
#10
JOURNAL ARTICLE
Matthew Webber, George Joy, Jonathan Bennett, Fiona Chan, Debbie Falconer, Hunain Shiwani, Rhodri H Davies, Gunther Krausz, Slobodan Tanackovic, Christoph Guger, Pablo Gonzalez, Emma Martin, Andrew Wong, Alicja Rapala, Kenan Direk, Peter Kellman, Iain Pierce, Yoram Rudy, Ramya Vijayakumar, Nishi Chaturvedi, Alun D Hughes, James C Moon, Pier D Lambiase, Xuyuan Tao, Vladan Koncar, Michele Orini, Gabriella Captur
BACKGROUND: Electrocardiographic imaging (ECGI) generates electrophysiological (EP) biomarkers while cardiovascular magnetic resonance (CMR) imaging provides data about myocardial structure, function and tissue substrate. Combining this information in one examination is desirable but requires an affordable, reusable, and high-throughput solution. We therefore developed the CMR-ECGI vest and carried out this technical development study to assess its feasibility and repeatability in vivo...
December 4, 2023: Journal of Cardiovascular Magnetic Resonance
#11
JOURNAL ARTICLE
Kevin Wiley, Justin Blackburn, Eneida Mendonca, Nir Menachemi, Mary De Groot, Joshua R Vest
PURPOSE: To examine the longitudinal relationship between the age or shelf-life of common type 2 diabetes laboratory tests for serum creatinine, cholesterol, and glycated hemoglobin A1c conducted in outpatient settings and subsequent inpatient hospitalizations and emergency department visits. METHODS: This study analyzes panel data from two healthcare delivery systems' electronic health records (EHR) for patients aged 18 years and older managing type 2 diabetes...
December 2023: Journal of Diabetes and Metabolic Disorders
#12
JOURNAL ARTICLE
Alex Ahebwa, Jeffrey Hii, Kok-Boon Neoh, Theerachart Leepasert, Theeraphap Chareonviriyaphap
Volatile pyrethroids exert a range of both lethal and behavioral effects on mosquitoes through the passive release of insecticides into the atmosphere. We investigated the protective efficacy (PE) of transfluthrin-treated jute (TI-jute) and cotton (TI-cotton) fabrics, worn at the back of a protective black vest, against laboratory-reared pyrethroid susceptible and resistant strains of Aedes aegypti (L.) in a semifield system (SFS). Each fabric (1,029 cm2) was treated with 1.79 mg/cm2 of transfluthrin as the intervention...
November 4, 2023: Journal of Medical Entomology
#13
JOURNAL ARTICLE
Maya R Sternberg, Amelia Johnson, Justice King, Akilah R Ali, Lauren Linde, Abiola O Awofeso, Jodee S Baker, Nagla S Bayoumi, Steven Broadway, Katherine Busen, Carolyn Chang, Iris Cheng, Mike Cima, Abi Collingwood, Vajeera Dorabawila, Cherie Drenzek, Aaron Fleischauer, Ashley Gent, Amanda Hartley, Liam Hicks, Mikhail Hoskins, Amanda Jara, Amanda Jones, Saadiah I Khan, Ishrat Kamal-Ahmed, Sarah Kangas, Fnu Kanishka, Alison Kleppinger, Anna Kocharian, Tomás M León, Ruth Link-Gelles, B Casey Lyons, John Masarik, Andrea May, Donald McCormick, Stephanie Meyer, Lauren Milroy, Keeley J Morris, Lauren Nelson, Enaholo Omoike, Komal Patel, Michael Pietrowski, Melissa A Pike, Tamara Pilishvili, Xandy Peterson Pompa, Charles Powell, Kevin Praetorius, Eli Rosenberg, Adam Schiller, Mayra L Smith-Coronado, Emma Stanislawski, Kyle Strand, Buddhi P Tilakaratne, Hailey Vest, Caleb Wiedeman, Allison Zaldivar, Benjamin Silk, Heather M Scobie
BACKGROUND: SARS-CoV-2 Omicron variants have the potential to impact vaccine effectiveness and duration of vaccine-derived immunity. We analyzed U.S. multi-jurisdictional COVID-19 vaccine breakthrough surveillance data to examine potential waning of protection against SARS-CoV-2 infection for the Pfizer-BioNTech (BNT162b) primary vaccination series by age. METHODS: Weekly numbers of SARS-CoV-2 infections during January 16, 2022-May 28, 2022 were analyzed by age group from 22 U...
2023: PloS One
#14
Allison N Akers, Adriana Vest, Claudio V Schenone, Alejandro Rodriguez
Strongyloidiasis is a parasitic infection with a high global burden of disease. Hyperinfection syndrome is a life-threatening complication that predominantly affects immunosuppressed individuals, such as those receiving corticosteroid treatment. Despite its worldwide prevalence, little is known about the clinical effects of this condition on the feto-maternal dyad during pregnancy. We present a case of placental abruption leading to preterm delivery in a pregnancy complicated by Strongyloides stercoralis hyperinfection syndrome following antenatal corticosteroid use...
August 2023: Curēus
#15
JOURNAL ARTICLE
Anne Vest Soerensen, Jakob Kjellberg, Rikke Ibsen, Lars Bastholt, Henrik Schmidt, Inge Marie Svane
BACKGROUND: Real-life data on health care costs and loss of productivity after implementing new agents for metastatic melanoma are important to supplement model-based economic data. MATERIALS AND METHODS: All patients registered in the Danish Metastatic Melanoma Database (DAMMED) and the National Patient Registry in 2007-2011 were compared to 2012-2016 after the implementation of checkpoint inhibitors and targeted therapy. Health care costs, social transfer income (STI), and loss of productivity were calculated with a 2-step one model generalised linear regression (GLM) model...
August 19, 2023: European Journal of Cancer
#16
JOURNAL ARTICLE
Mariam Reda, Abhijit Sen, Manal Mustafa
BACKGROUND: Immigrants are known to experience greater socioeconomic stress and poorer well-being and to suffer more from lifestyle- and diet-related disorders than native populations. There is also evidence that children of immigrant parents are at greater risk of diverse health problems than their host country cohorts. The aim of this study is to apply and evaluate the efficacy of an early life intervention program among parents/children with immigrant background to prevent childhood caries and obesity, thereby improving the children's general health, oral health, and quality of life...
September 1, 2023: BMC Oral Health
#17
JOURNAL ARTICLE
Prajakta Badri, Bahru Habtemariam, Megan Melch, Valerie A Clausen, Seth Arum, Xingyu Li, Patrick Y Jay, John Vest, Gabriel J Robbie
BACKGROUND AND OBJECTIVE: Variants of the transthyretin (TTR) gene cause hereditary transthyretin-mediated (hATTR) amyloidosis, or ATTRv amyloidosis (v for variant), which results from deposition of misfolded TTR protein as amyloid in organs and tissues. Patisiran is an RNA interference (RNAi) therapeutic that suppresses the hepatic production of TTR protein. Patisiran improves multiple clinical manifestations of hATTR amyloidosis in patients without liver transplantation (LT). Because the liver is the predominant source of circulating TTR, LT has been prescribed to eliminate the production of the variant TTR...
August 28, 2023: Clinical Pharmacokinetics
#18
JOURNAL ARTICLE
Keshu Yin, Dongli Zhou, Kun Tan, Shiji Li, Mengxiao Zhao, Qiong Lu, Chunlin Teng, Xihong Lu
It is very necessary to design a high-capacity and stable Bi2 O3 anode for nickel-bismuth (Ni//Bi) batteries. In this work, a stable α- and β- phase Bi2 O3 heterojunction nanocomposite (α/β - Bi2 O3 ) was successfully prepared via a simple "space-confined" strategy and it was used as a superior anode for nickel-bismuth (Ni//Bi) battery. The α/β-Bi2 O3 obtained by using MCM-41 as a space-confined template possesses a stable structure and enhanced charge transfer capability...
August 8, 2023: Journal of Colloid and Interface Science
#19
REVIEW
Zubair Umer Mohamed, Christi Titus Varghese, Abish Sudhakar, Lakshmi Kumar, Unnikrishnan Gopalakrishnan, Dinesh Balakrishnan, Ramachandran Narayanamenon, Surendran Sudhindran
BACKGROUND: Prostaglandins are naturally occurring lipids that are synthesised from arachidonic acid. Multiple studies have evaluated the benefits of prostaglandins in reducing ischaemia reperfusion injury after liver transplantation. New studies have been published since the previous review, and hence it was important to update the evidence for this intervention. OBJECTIVES: To evaluate the benefits and harms of prostaglandins in adults undergoing liver transplantation compared with placebo or standard care...
August 4, 2023: Cochrane Database of Systematic Reviews
#20
REVIEW
Peng Zhu, Sitong Dong, Ping Sun, Ajay P Belgaumkar, Yi Sun, Xiang Cheng, Qichang Zheng, Tong Li
BACKGROUND: Transjugular intrahepatic portosystemic shunt (TIPS) is a widely used procedure for management of uncontrolled upper gastrointestinal bleeding and refractory ascites in people with liver cirrhosis. However, nearly half of the people experience shunt dysfunction and recurrent symptoms within one year of the procedure. Expanded polytetrafluoroethylene (ePTFE)-covered stents are assumed to decrease shunt dysfunction by approximately 20% to 30%. OBJECTIVES: To evaluate the benefits and harms associated with the use of expanded polytetrafluoroethylene (ePTFE)-covered stents versus bare stents in transjugular intrahepatic portosystemic shunts (TIPSs) for managing people with liver cirrhosis...
August 2, 2023: Cochrane Database of Systematic Reviews
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