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https://www.readbyqxmd.com/read/28529366/wisconsin-card-sorting-test-performance-impairment-in-schizophrenia-an-indian-study-report
#1
Shailja Singh, Tapas Kumar Aich, Raju Bhattarai
AIM: The present study attempted to find out the relationship between positive and negative clinical symptoms and Wisconsin Card Sorting Test (WCST) performance in a group of schizophrenia patients. METHODOLOGY: Fifty schizophrenia patients were assessed using the Positive and Negative Syndrome Scale (PANSS) by a trained psychiatrist (TKA) and two groups, each of 25 positive symptom and 25 negative symptom schizophrenia patients were formed. On these fifty patients with schizophrenia and 15 normal control groups, WCST measures were applied by a clinical psychologist (SS) who remained blind to the PANSS score...
January 2017: Indian Journal of Psychiatry
https://www.readbyqxmd.com/read/28527205/moderate-physical-activity-is-associated-with-cerebral-glucose-metabolism-in-adults-at-risk-for-alzheimer-s-disease
#2
Ryan J Dougherty, Stephanie A Schultz, Taylor K Kirby, Elizabeth A Boots, Jennifer M Oh, Dorothy Edwards, Catherine L Gallagher, Cynthia M Carlsson, Barbara B Bendlin, Sanjay Asthana, Mark A Sager, Bruce P Hermann, Bradley T Christian, Sterling C Johnson, Dane B Cook, Ozioma C Okonkwo
The objective of this study was to investigate the relationship between accelerometer-measured physical activity (PA) and glucose metabolism in asymptomatic late-middle-aged adults. Ninety-three cognitively healthy late-middle-aged adults from the Wisconsin Registry for Alzheimer's Prevention participated in this cross-sectional study. They underwent 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) imaging and wore an accelerometer (ActiGraph GT3X+) to measure free-living PA. Accelerometer data yielded measures of light (LPA), moderate (MPA), and vigorous (VPA) intensity PA...
May 17, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28526254/associations-between-midlife-insomnia-symptoms-and-earlier-retirement
#3
Lauren Hale, Lee Singer, Jodi H Barnet, Paul E Peppard, Erika W Hagen
BACKGROUND: Insomnia symptoms are prevalent and associated with impaired health and well-being. However, scant research has investigated whether midlife insomnia symptoms are also associated with earlier retirement, thereby contributing to additional economic consequences. PARTICIPANTS AND METHODS: We analyzed data from a community-based sample of 1635 Wisconsin State employees (51.6% women) that were collected from 1988 until 2014. Study participants were asked about insomnia symptoms (difficulty getting to sleep, difficulty getting back to sleep, repeated nocturnal awakenings, and early morning awakenings) in midlife, with prospective follow-up questions about the specific reasons for retirement between 2010 and 2014...
June 2017: Sleep Health
https://www.readbyqxmd.com/read/28525633/scan-echo-for-pain-management-implementing-a-regional-telementoring-training-for-primary-care-providers
#4
Sherry Ball, Brigid Wilson, Scott Ober, Ali Mchaourab
Objective.:  The Specialty Care Access Network-Extension for Community Health Outcomes (SCAN-ECHO) is a video teleconferencing-based training program where primary care providers are trained by a specialty care team to provide specialty care. A multidisciplinary team of pain management specialists at the Cleveland Veterans Affairs Medical Center established such a program for pain management; a description and preliminary effectiveness assessment of this training program is presented...
May 19, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/28522895/a-hearing-loss-prevention-outreach-program-for-farmers-and-motorsports-enthusiasts
#5
REVIEW
Melanie Buhr-Lawler
Many farmers and motorsports enthusiasts in rural areas attend tractor pulls, which are loud motorsport competitions using tractors and trucks with powerful, modified engines. The high noise levels experienced by farmers and motorsports fans in their recreational and occupational activities are not addressed by traditional hearing conservation programs. The University of Wisconsin-Madison audiology group has established an annual hearing loss prevention outreach project at the Dairyland Super National Truck and Tractor Pull in Tomah, Wisconsin...
May 2017: Seminars in Hearing
https://www.readbyqxmd.com/read/28521281/functional-connectivity-in-incarcerated-male-adolescents-with-psychopathic-traits
#6
Sandra Thijssen, Kent A Kiehl
The present study examined the association between psychopathic traits and functional connectivity in 177 incarcerated male adolescents. We hypothesized that psychopathic symptoms would be associated with functional connectivity within networks encompassing limbic and paralimbic regions, such as the default mode (DMN), salience networks (SN), and executive control network (ECN). The present sample was drawn from the Southwest Advanced Neuroimaging Cohort, Youth sample, and from research at a youth detention facility in Wisconsin...
May 11, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28520981/clinical-presentation-and-outcomes-of-children-with-human-granulocytic-anaplasmosis
#7
Anna M Schotthoefer, Matthew C Hall, Satya Vittala, Raza Bajwa, Holly M Frost
Background.: Adults with the tick-borne disease human granulocytic anaplasmosis (HGA) have a spectrum of acute febrile illnesses that, if untreated, might be severe. Clinical presentation and outcomes of children with HGA have been poorly described. Methods.: A retrospective analysis was conducted to determine the frequency, presentation, and outcomes of pediatric patients with HGA between 1994 and 2015 in a region of Wisconsin in which HGA is highly endemic. Patients with related International Classification of Diseases Ninth and Tenth Revision (ICD-9 and ICD-10, respectively) codes or positive HGA laboratory test results were evaluated and classified as having had confirmed, probable, or suspected HGA on the basis of the Centers for Disease Control and Prevention (CDC) case definition...
May 16, 2017: Journal of the Pediatric Infectious Diseases Society
https://www.readbyqxmd.com/read/28516153/neutrophil-to-lymphocyte-ratio-nlr-at-the-time-of-transurethral-resection-of-bladder-tumor-a-large-retrospective-study-and-analysis-of-racial-differences
#8
Ngii N Tazeh, Daniel J Canter, Shivashankar Damodaran, Timothy Rushmer, Kyle A Richards, E Jason Abel, David F Jarrard, Tracy M Downs
Introduction: Neutrophil/lymphocyte ratio (NLR) is an indicator of systemic inflammation and has been proven to be associated with an increased risk of extravesical disease, decreased cancer specific survival and overall survival in bladder cancer patients. A large proportion of healthy African Americans have a WBC count that is persistently lower than the normal range defined for individuals of European ancestry, this condition has been called "benign ethnic neutropenia". The purpose of our study was to determine if NLR was different in patients of African ancestry (AA) vs European ancestry (EA) across different tumor grades and stages at the time of transurethral resection of bladder tumor(s) (TURBT)...
April 27, 2017: Bladder Cancer
https://www.readbyqxmd.com/read/28503533/effect-of-core-strengthening-with-pelvic-proprioceptive-neuromuscular-facilitation-on-trunk-balance-gait-and-function-in-chronic-stroke
#9
Vishal Sharma, Jaskirat Kaur
The purpose of this study was to evaluate the effects of core strengthening combined with pelvic proprioceptive neuromuscular facilitation (PNF) on trunk impairment, balance, gait, and functional ability of chronic stroke patients. Twenty-three participants with chronic stroke were recruited and randomly allocated to one of the two groups: core strengthening combined with pelvic PNF (group 1, n=13), and pelvic PNF with trunk flexibility exercises (group 2, n=10). Intervention was given to both groups for 60 min per session 5 times per week for 4 weeks...
April 2017: Journal of Exercise Rehabilitation
https://www.readbyqxmd.com/read/28502050/biogeochemical-controls-on-mercury-methylation-in-the-allequash-creek-wetland
#10
Joel E Creswell, Martin M Shafer, Christopher L Babiarz, Sue-Zanne Tan, Abbey L Musinsky, Trevor H Schott, Eric E Roden, David E Armstrong
We measured mercury methylation potentials and a suite of related biogeochemical parameters in sediment cores and porewater from two geochemically distinct sites in the Allequash Creek wetland, northern Wisconsin, USA. We found a high degree of spatial variability in the methylation rate potentials but no significant differences between the two sites. We identified the primary geochemical factors controlling net methylmercury production at this site to be acid-volatile sulfide, dissolved organic carbon, total dissolved iron, and porewater iron(II)...
May 13, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28501399/effect-of-feeding-strategies-and-cropping-systems-on-greenhouse-gas-emission-from-wisconsin-certified-organic-dairy-farms
#11
D Liang, F Sun, M A Wattiaux, V E Cabrera, J L Hedtcke, E M Silva
Organic agriculture continues to expand in the United States, both in total hectares and market share. However, management practices used by dairy organic producers, and their resulting environmental impacts, vary across farms. This study used a partial life cycle assessment approach to estimate the effect of different feeding strategies and associated crop production on greenhouse gas emissions (GHG) from Wisconsin certified organic dairy farms. Field and livestock-driven emissions were calculated using 2 data sets...
May 10, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28501376/six-year-incidence-of-age-related-macular-degeneration-in-asian-malays-the-singapore-malay-eye-study
#12
Chui Ming Gemmy Cheung, Peng Guan Ong, Kumari Neelam, Pok Chien Tan, Yuan Shi, Paul Mitchell, Jie Jin Wang, Charumathi Sabanayagam, Ching-Yu Cheng, Tien Yin Wong
PURPOSE: To determine the 6-year incidence of early and late age-related macular degeneration (AMD) in a Singaporean Malay population and to validate the Age-Related Eye Disease Study (AREDS) simplified severity scale in Asians. DESIGN: Prospective, population cohort study. PARTICIPANTS: The Singapore Malay Eye Study baseline participants (age, ≥40 years; 2006-2008) were followed up in 2011 through 2013, and 1901 of 3280 of eligible participants (72...
May 10, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28498498/impact-of-prescription-drug-monitoring-programs-pdmps-on-opioid-utilization-among-medicare-beneficiaries-in-10-u-s-states
#13
Patience Moyo, Linda Simoni-Wastila, Beth Ann Griffin, Eberechukwu Onukwugha, Donna Harrington, G Caleb Alexander, Francis Palumbo
BACKGROUND AND AIMS: Prescription Drug Monitoring Programs (PDMPs) are a principal strategy used in the USA to address prescription drug abuse. We (1) compared opioid use pre- and post-PDMP implementation and (2) estimated differences of PDMP impact by reason for Medicare eligibility and plan type. DESIGN: Analysis of opioid prescription claims in US states that implemented PDMPs relative to non-PDMP states during 2007-2012. SETTING: Florida, Louisiana, Nebraska, New Jersey, Vermont, Georgia, Wisconsin, Maryland, New Hampshire, and Arkansas, USA...
May 12, 2017: Addiction
https://www.readbyqxmd.com/read/28496993/successful-application-of-whole-genome-sequencing-in-a-medical-genetics-clinic
#14
David Bick, Pamela C Fraser, Michael F Gutzeit, Jeremy M Harris, Tina M Hambuch, Daniel C Helbling, Howard J Jacob, Juliet N Kersten, Steven R Leuthner, Thomas May, Paula E North, Sasha Z Prisco, Bryce A Schuler, Mary Shimoyama, Kimberly A Strong, Scott K Van Why, Regan Veith, James Verbsky, Arthur M Weborg, Brandon M Wilk, Rodney E Willoughby, Elizabeth A Worthey, David P Dimmock
A pilot program was initiated using whole genome sequencing (WGS) to diagnose suspected genetic disorders in the Genetics Clinic at Children's Hospital of Wisconsin. Twenty-two patients underwent WGS between 2010 and 2013. Initially, we obtained a 14% (3/22) diagnosis rate over 2 years; with subsequent reanalysis, this increased to 36% (8/22). Disease causing variants were identified in SKIV2L, CECR1, DGKE, PYCR2, RYR1, PDGFRB, EFTUD2, and BCS1L. In 75% (6/8) of diagnosed cases, the diagnosis affected treatment and/or medical surveillance...
June 2017: Journal of Pediatric Genetics
https://www.readbyqxmd.com/read/28495511/biomolecular-nmr-past-and-future
#15
John L Markley, William Milo Westler
The editors of this special volume suggested this topic, presumably because of the perspective lent by our combined >90-year association with biomolecular NMR. What follows is our personal experience with the evolution of the field, which we hope will illustrate the trajectory of change over the years. As for the future, one can confidently predict that it will involve unexpected advances. Our narrative is colored by our experience in using the NMR Facility for Biomedical Studies at Carnegie-Mellon University (Pittsburgh) and in developing similar facilities at Purdue (1977-1984) and the University of Wisconsin-Madison (1984-)...
May 8, 2017: Archives of Biochemistry and Biophysics
https://www.readbyqxmd.com/read/28494877/prevalence-of-malignant-hyperthermia-diagnosis-in-hospital-discharge-records-in-california-florida-new-york-and-wisconsin
#16
Zhen Lu, Henry Rosenberg, Guohua Li
STUDY OBJECTIVE: Malignant hyperthermia (MH) is a rare yet potentially fatal pharmacogenetic disorder triggered by exposure to inhalational anesthetics and the depolarizing neuromuscular blocking agent succinylcholine. Epidemiologic data on the geographic variation in MH prevalence is scant. The objective of this study is to examine the prevalence of recorded MH diagnosis in patients discharged from hospitals in four states in the United States. DESIGN: Observational study...
June 2017: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/28494819/mild-cognitive-impairment-in-parkinson-s-disease-clustering-and-switching-analyses-in-verbal-fluency-test
#17
Iván Galtier, Antonieta Nieto, Jesús N Lorenzo, José Barroso
OBJECTIVES: Mild cognitive impairment is common in non-demented Parkinson disease patients (PD-MCI) and is considered as a risk factor for dementia. Executive dysfunction has been widely described in PD and the Verbal Fluency Tests (VFT) are often used for executive function assessment in this pathology. The Movement Disorder Society (MDS) published guidelines for PD-MCI diagnosis in 2012. However, no investigation has focused on the qualitative analysis of VFT in PD-MCI. The aim of this work was to study the clustering and switching strategies in VFT in PD-MCI patients...
May 12, 2017: Journal of the International Neuropsychological Society: JINS
https://www.readbyqxmd.com/read/28494623/validity-of-the-wisconsin-card-sorting-test-in-patients-with-stroke
#18
En-Chi Chiu, Wen-Chi Wu, Jen-Wen Hung, Yu-Hsuan Tseng
BACKGROUND: The Wisconsin Card Sorting Test (WCST) is the most widely used measure for assessing executive functions in patients with stroke. However, no study has examined the ecological, discriminative and convergent validities of the WCST in patients with stroke. This study aimed to examine the above validities of the WCST in patients with stroke. METHODS: Ninety-eight patients were administered the WCST, two measures of activities of daily living and one cognitive measure...
May 11, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28492872/urinary-isoprostane-levels-and-age-related-macular-degeneration
#19
Charumathi Sabanayagam, Weng Kit Lye, Andrzej Januszewski, Riswana Banu Binte Mohammed Abdul, Gemmy Chui Ming Cheung, Neelam Kumari, Tien Y Wong, Ching-Yu Cheng, Ecosse Lamoureux
Purpose: Oxidative stress, characterized by an excessive production of reactive oxygen intermediates has been suggested to play a role in the pathogenesis of age-related macular degeneration (AMD). We examined the association of urinary F2-isoprostanes (F2-IsoPs), a marker of lipid peroxidation and the most reliable marker of oxidative damage with AMD. Methods: We included 238 adults with AMD and 390 age- and sex-matched controls without AMD who participated in a population-based cross-sectional study in Singapore (Singapore Chinese Eye Study, 2009-2011)...
May 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28492862/establishing-baseline-normative-values-for-the-child-sport-concussion-assessment-tool
#20
M Alison Brooks, Traci R Snedden, Benjamin Mixis, Scott Hetzel, Timothy A McGuine
Importance: The Child Sport Concussion Assessment Tool (SCAT3) is a postconcussion sideline assessment tool measuring symptoms, cognition, and balance in preadolescent children. Minimal normative baseline data exist to aid decision making in clinical and athletic settings. Objective: To collect normative baseline data for the Child SCAT3 in a large cohort of young athletes. Design, Setting, and Participants: A cross-sectional study was conducted from May 31 to August 12, 2014, at various sporting events (basketball, soccer, baseball, and swimming) in Central Wisconsin among children 5 to 13 years of age who were English-speaking and did not report a lower leg injury within the past 2 months or a concussion within the past month...
May 8, 2017: JAMA Pediatrics
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