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Tao Yang, Guoqing Zhao, Ruizhi Mao, Jia Huang, Xianrong Xu, Yousong Su, Na Zhu, Rubai Zhou, Xiao Lin, Weiping Xia, Fan Wang, Rui Liu, Xing Wang, Zhijia Huang, Yong Wang, Yingyan Hu, Lan Cao, Chengmei Yuan, Zuowei Wang, Raymond W Lam, Jun Chen, Yiru Fang
BACKGROUND: The aims of this study were to investigate the differences in executive function and the relationship with clinical factors between drug-naïve patients with bipolar depression (BDD) and unipolar depression (UPD). METHODS: Drug-naïve patients with BDD, UPD and healthy controls (HC) were recruited (30 cases in each group). All patients were assessed with Hamilton Rating Scale for Anxiety (HAM-A), Hamilton Rating Scale for Depression-17 (HAM-D), and Young Mania Rating Scale (YMRS)...
May 29, 2018: Journal of Affective Disorders
Justin M Siewert, James A Salfer, Marcia I Endres
The objective of this study was to identify housing and management factors associated with productivity on automatic milking system (AMS) dairy farms measured as daily milk yield/AMS and daily milk yield/cow. Management, housing, and lameness prevalence data were collected from 33 AMS farms in Minnesota and Wisconsin during a farm visit. All farms in the study used free-flow cow traffic. Mixed model analysis of cross-sectional data showed that farms with automatic feed push-up via a robot produced more milk per AMS/day and per cow/day than farms where feed was pushed up manually...
June 13, 2018: Journal of Dairy Science
Richard S Mangus, Joel R Schroering, Taylor J Hathaway, Chandrashekhar A Kubal, Jonathan A Fridell
UW and HTK solutions are the two primary organ preservation solutions most used in the United States. This study analyzes use of the two solutions in all pediatric liver transplants performed at a single center between 2001and 2017. Outcome measures included early graft function, as well as graft and patient survival. Bile duct complications were reviewed. Operative technique, immunosuppressive protocols, and donor acceptance criteria remained uniform among participating surgeons throughout the study period...
June 15, 2018: Pediatric Transplantation
Shira Cohen-Zimerman, Ran R Hassin
It is widely accepted that while controlled processes (e.g., working memory and executive functions) decline with age, implicit (automatic) processes are not affected by age. In this paper we challenge this view by arguing that high-level automatic processes (e.g., recruiting motivation) decline with age, and that this decline plays an unappreciated role in cognitive aging. Specifically, we hypothesized that due to their decline, automatic motivational processes are less likely to be spontaneously activated in old age; thus, implicit external activation of them should have stronger effects on older (vs...
June 12, 2018: Consciousness and Cognition
Kelsey L Paras, Melissa M George, Anand N Vidyashankar, Ray M Kaplan
Gastrointestinal nematode parasites are important pathogens of all domesticated livestock species. Fecal egg counts (FEC) are routinely used for evaluating anthelmintic efficacy and for making targeted anthelmintic treatment decisions. Numerous FEC techniques exist and vary in precision and accuracy. These performance characteristics are especially important when performing fecal egg count reduction tests (FECRT). The objective of this study was to compare the accuracy and precision of three commonly used FEC methods and determine if differences existed among livestock species...
June 15, 2018: Veterinary Parasitology
Kathrine L Barnes, Jeffrey J VanWormer, Shannon Stokley, Elizabeth R Vickers, Huong Q McLean, Edward A Belongia, Casper G Bendixsen
BACKGROUND: Parental attitudes play a key role in their decisions to vaccinate adolescents against the human papillomavirus (HPV). Little is known, however, about the formative experiences that shape parents' attitudes about the HPV vaccine. METHODS: We conducted semi-structured interviews with 25 parents of 11-17 year old adolescents in Wisconsin who changed their HPV vaccine attitudes (per prior surveys) over one year. A modified grounded theory approach was then used to generate primary themes of attitudinal determinants...
June 15, 2018: BMC Public Health
Stephanie M Jagemann, Jennifer Juzwik, Patrick C Tobin, Kenneth F Raffa
Oak wilt is a lethal disease caused by the invasive fungus Bretziella fagacearum, which is transmitted belowground via root grafts and aboveground by sap beetles (Nitidulidae). Attempts to limit spread and impact of B. fagacearum emphasize limiting harvesting and pruning to periods of vector inactivity. However, there is limited information on sap beetle activity periods, responses to temperature, and phoresy frequencies of fungi. We sampled two major vectors in Wisconsin, Colopterus truncatus and Carpophilus sayi, for 2 yr to quantify their seasonal and geographic abundances...
June 14, 2018: Environmental Entomology
D Cocking, J Cinatl, D A Boltz, X Peng, W Johnson, M Muzzio, O Syarkevych, G Kostyuk, A Goy, L Mueller, V I Margitich
With only a single class of antiviral drugs existing for treatment of influenza (neuraminidase inhibitors), the search for novel effective compounds is urgently needed. We evaluated a low molecular mass compound, enisamium iodide (FAV00A), against influenza virus infections in primary differentiated normal human bronchial epithelial (NHBE) cells, and in ferrets. FAV00A (500 µg/ml) markedly inhibited influenza virus replication and reduced viral M-gene expression in NHBE cells. Treatment of ferrets with FAV00A (200 mg/kg once daily for 7 days) initiated 24 h after inoculation with 105 TCID50 of influenza A/Wisconsin/67/2005 (H3N2) virus resulted in a significant decrease in virus titers in the upper respiratory tract...
2018: Acta Virologica
Payam Zarbakhsh, Abdoljalil Addeh
Context: Breast cancer is a major cause of mortality in young women in the developing countries. Early diagnosis is the key to improve survival rate in cancer patients. Aims: In this paper an intelligent system is proposed to breast cancer tumor type recognition. Settings and Design: The proposed system includes three main module: The feature selection module, the classifier module and the optimization module. Feature selection plays an important role in pattern recognition systems...
April 2018: Journal of Cancer Research and Therapeutics
Elizabeth Gyllstrom, Kimberly Gearin, Donald Nease, Betty Bekemeier, Rebekah Pratt
OBJECTIVE: To describe the degree of public health and primary care collaboration at the local level and develop a model framework of collaboration, the Community Collaboration Health Model (CCHM). DESIGN: Mixed-methods, cross-sectional surveys, and semistructured, key informant interviews. SETTING: All local health jurisdictions in Colorado, Minnesota, Washington, and Wisconsin. PARTICIPANTS: Leaders from each jurisdiction were identified to describe local collaboration...
June 7, 2018: Journal of Public Health Management and Practice: JPHMP
Paula A Keller, Raymond G Boyle, Rebecca K Lien, Bruce Christiansen, Kate Kobinsky
Although telephone quitlines are effective for helping smokeless tobacco (ST) users quit, ST users are underrepresented among quitline participants. After ClearWay Minnesota implemented multiple changes to its quitline service (QUITPLAN® Services), utilization increased dramatically, including by ST users. We examined data from Minnesota and Wisconsin to determine whether these changes were unique to Minnesota. Four years of quitline registration data were analyzed for both states. A significant increase in enrollees reporting any ST use was seen in Minnesota after changes were made to services; no change was seen in Wisconsin...
June 7, 2018: Journal of Public Health Management and Practice: JPHMP
Pedro Barata, Hamid Emamekhoo, Prateek Mendiratta, Vadim Koshkin, Allison Tyler, Moshe Ornstein, Brian I Rini, Timothy Gilligan, Christos Kyriakopoulos, Jorge A Gracia
BACKGROUND: Androgen deprivation therapy plus docetaxel (D-ADT) increases overall survival (OS) in men with high-volume, metastatic hormone-sensitive prostate cancer (mHSPC). Although the vast majority of men initially respond to D-ADT, most will progress and develop castration-resistant prostate cancer (CRPC). Little is known about the optimal treatment sequence for men with progressive disease on D-ADT. PATIENT AND METHODS: Retrospective analysis of consecutive mHSPC patients treated with ≥3 cycles of D-ADT at Cleveland Clinic and University of Wisconsin-Madison was undertaken...
June 7, 2018: Prostate
Trevor Birkey, Jennifer Dixon, Roni Jacobsen, Salil Ginde, Melodee Nugent, Ke Yan, Pippa Simpson, Joshua Kovach
Adult congenital heart disease (ACHD) patients often require repeat cardiothoracic surgery, which may result in significant morbidity and mortality. Currently, there are few pre-operative risk assessment tools available. In the general adult population, pre-operative cardiopulmonary exercise testing (CPET) has a predictive value for post-operative morbidity and mortality following major non-cardiac surgery. The utility of CPET for risk assessment in ACHD patients requiring cardiothoracic surgery has not been evaluated...
June 7, 2018: Pediatric Cardiology
H Zhang, S Gao, L Yan, G Zhu, Q Zhu, Y Gu, F Shao
BACKGROUND: The goal of this study was to analyze the protective role of ARA290 in early renal allograft injury by using a rat model of renal allograft. METHODS: Lewis rats were divided into 3 groups: sham, University of Wisconsin solution (UW), and ARA290. A rat model of renal allograft was established by anastomosis using a titanium ring pin stapler. The kidneys were removed 24 hours after transplantation to accomplish the following: (1) examine the protective effect of ARA290 on renal morphology and function; (2) investigate the underlying mechanism by determining the binding affinity of nuclear factor-κB (NF-κB) to DNA by using an electrophoretic mobility shift assay; (3) observe the effect of ARA290 on macrophage infiltration using immunohistochemistry; and (4) detect messenger RNA (mRNA) expression of inflammatory mediators by using reverse transcriptase polymerase chain reaction...
June 2018: Transplantation Proceedings
Bradley S Cohen, Emily H Belser, Shamus P Keeler, Michael J Yabsley, Karl V Miller
Trueperella pyogenes, a bacterial opportunistic pathogen residing along the skin layer of apparently healthy animals, is the etiologic agent of intracranial abscessation-suppurative meningoencephalitis, a cause of mortality for male white-tailed deer ( Odocoileus virginianus). Occurrence of this disease has been speculated to be influenced by virulence of T. pyogenes residing on white-tailed deer in geographically distinct metapopulations. To determine if differences in virulence potential of T. pyogenes could affect occurrence of disease across populations, we examined if frequency of seven virulence genes of T...
June 7, 2018: Journal of Wildlife Diseases
Naren Rao, Georg Northoff, Abanti Tagore, Pablo Rusjan, Miran Kenk, Alan Wilson, Sylvain Houle, Antonio Strafella, Gary Remington, Romina Mizrahi
Evidence from several lines of research suggests decreased dopamine release in the prefrontal cortex as the neurochemical correlates of cognitive deficits in schizophrenia (SCZ). However, in vivo examination of cortical hypodopaminergia using positron emission tomography (PET) during cognitive task performance in SCZ remains to be investigated. We examined dopamine release in anterior cingulate cortex (ACC) and dorsolateral prefrontal cortex (DLPFC), using PET while participants were performing a cognitive task...
June 7, 2018: Schizophrenia Bulletin
Cristina Baglivo, Paolo Maria Congedo
Several technical combinations have been evaluated in order to design high energy performance buildings for the warm climate. The analysis has been developed in several steps, avoiding the use of HVAC systems. The methodological approach of this study is based on a sequential search technique and it is shown on the paper entitled "Envelope Design Optimization by Thermal Modeling of a Building in a Warm Climate" [1]. The Operative Air Temperature trends (TOP), for each combination, have been plotted through a dynamic simulation performed using the software TRNSYS 17 (a transient system simulation program, University of Wisconsin, Solar Energy Laboratory, USA, 2010)...
April 2018: Data in Brief
Jody D Ciolino, Kathryn L Jackson, David T Liss, Tiffany Brown, Theresa L Walunas, Linda Murakami, Isabel Chung, Stephen D Persell, Abel N Kho
BACKGROUND: The Healthy Hearts in the Heartland (H3) study is part of a nationwide effort, EvidenceNOW, seeking to better understand the ability of small primary care practices to improve "ABCS" clinical quality measures: appropriate Aspirin therapy, Blood pressure control, Cholesterol management, and Smoking cessation. H3 aimed to assess feasibility of implementing Point-of-Care (POC) or POC plus Population Management (POC + PM) quality improvement (QI) strategies to improve ABCS at practices in Illinois, Indiana, and Wisconsin...
June 2, 2018: Contemporary Clinical Trials
Corinne A Riddell, Kathryn T Morrison, Jay S Kaufman, Sam Harper
Life expectancy has increased in the United States over many decades. The difference in life expectancy between black and white Americans has also decreased, but some states have made much more progress towards racial equality than others. This paper describes the pattern of contributions of six major causes of death to the black-white life expectancy gap within US states and the District of Columbia between 1969 and 2013, and identifies states diverging from the overall pattern. Across multiple causes, the District of Columbia, Illinois, Wisconsin, and Michigan had the highest contributions to black-white inequality, while New York, Massachusetts, and Rhode Island had the lowest contributions and have either achieved or are the closest to achieving black-white equality in life expectancy...
June 1, 2018: Health & Place
Xiaoyin Ke, Yi Ding, Ke Xu, Hongbo He, Daping Wang, Xuefeng Deng, Xifan Zhang, Yanling Zhou, Chao Zhou, Yuping Liu, Yuping Ning, Ni Fan
The aim of this study was to examine the cognitive function in chronic ketamine users. Factors correlated to cognition impairments were analyzed. Sixty-three chronic ketamine users and 65 healthy subjects were recruited. Cognitive function was assessed by using immediate/delayed visual reproduction (IVR/DVR) tasks, immediate/delayed logical memory (ILM/DLM) tasks, Stroop test, Wisconsin card sorting test (WCST), and continuous performance test (CPT). Psychopathological symptoms were assessed with the Positive and Negative Syndrome Scale (PANSS), Beck Depression Inventory (BDI) and Beck Anxiety Inventory (BAI)...
May 26, 2018: Psychiatry Research
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