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https://www.readbyqxmd.com/read/28210206/the-unc-wisconsin-rhesus-macaque-neurodevelopment-database-a-structural-mri-and-dti-database-of-early-postnatal-development
#1
Jeffrey T Young, Yundi Shi, Marc Niethammer, Michael Grauer, Christopher L Coe, Gabriele R Lubach, Bradley Davis, Francois Budin, Rebecca C Knickmeyer, Andrew L Alexander, Martin A Styner
Rhesus macaques are commonly used as a translational animal model in neuroimaging and neurodevelopmental research. In this report, we present longitudinal data from both structural and diffusion MRI images generated on a cohort of 34 typically developing monkeys from 2 weeks to 36 months of age. All images have been manually skull stripped and are being made freely available via an online repository for use by the research community.
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28196847/housing-discrimination-residential-racial-segregation-and-colorectal-cancer-survival-in-southeastern-wisconsin
#2
Yuhong Zhou, Amin Bemanian, Kirsten M M Beyer
BACKGROUND: Residential racial segregation is still neglected in contemporary examinations of racial health disparities, including studies of cancer. Even fewer studies examine the processes by which segregation occurs, such as through housing discrimination. This study aims to examine relationships among housing discrimination, segregation, and colorectal cancer survival in southeastern Wisconsin. METHODS: Cancer incidence data were obtained from the Wisconsin Cancer Reporting System for two southeastern Wisconsin metropolitan areas...
February 14, 2017: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/28194034/high-pressure-carbon-monoxide-preserves-rat-kidney-grafts-from-apoptosis-and-inflammation
#3
Toyofumi Abe, Koji Yazawa, Masayuki Fujino, Ryoichi Imamura, Naoyuki Hatayama, Yoichi Kakuta, Koichi Tsutahara, Masayoshi Okumi, Naotsugu Ichimaru, Jun-Ya Kaimori, Yoshitaka Isaka, Kunihiro Seki, Shiro Takahara, Xiao-Kang Li, Norio Nonomura
Renal ischemia-reperfusion (I/R) injury is unavoidable in kidney transplantation (KTx) and frequently influences both short- and long-term allograft survival. Carbon monoxide (CO) has attracted attention as a medical gas with anti-inflammatory and anti-apoptotic effects. We investigated a new strategy for organ preservation using ex vivo application of high-pressure CO in an experimental rat KTx model. We preserved kidney grafts using a high-pressure chamber filled with mixed gases composed of CO and O2. We found that cold I/R injury resulted in progressive deterioration of renal graft function in University of Wisconsin solution, whereas CO significantly improved renal function...
February 13, 2017: Laboratory Investigation; a Journal of Technical Methods and Pathology
https://www.readbyqxmd.com/read/28193558/allergic-disease-associations-with-regional-and-localized-estimates-of-air-pollution
#4
Amy A Schultz, Jamie J Schauer, Kristen Mc Malecki
BACKGROUND: Exposure to multiple types of air pollution may contribute to and exacerbate allergic diseases including asthma and wheezing. However, few studies have examined chronic air pollution exposure and allergic disease outcomes among an adult population. Associations between potential estimates of annual average fine particulate matter (PM2.5), traffic related air pollution, and industrial source air emissions and three allergic disease outcomes (asthma, allergies and wheezing) were examined in a state-wide general population of adults...
February 10, 2017: Environmental Research
https://www.readbyqxmd.com/read/28192769/disorganization-at-the-stage-of-schizophrenia-clinical-outcome-clinical-biological-study
#5
A Nestsiarovich, V Obyedkov, H Kandratsenka, M Siniauskaya, I Goloenko, N Waszkiewicz
BACKGROUND: According to the multidimensional model of schizophrenia, three basic psychopathological dimensions constitute its clinical structure: positive symptoms, negative symptoms and disorganization. The latter one is the newest and the least studied. Our aim was to discriminate disorganization in schizophrenia clinical picture and to identify its distinctive biological and socio-psychological particularities and associated genetic and environmental factors. METHODS: We used SAPS/SANS psychometrical scales, scales for the assessment of patient's compliance, insight, social functioning, life quality...
December 30, 2016: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/28192469/diatoms-on-the-carapace-of-common-snapping-turtles-luticola-spp-dominate-despite-spatial-variation-in-assemblages
#6
Shelly C Wu, Elizabeth A Bergey
Filamentous algae are often visible on the carapaces of freshwater turtles and these algae are dominated by a few species with varying geographic distributions. Compared to filamentous algae, little is known about the much more speciose microalgae on turtles. Our objectives were to compare the diatom flora on a single turtle species (the common snapping turtle, Chelydra serpentina) across part of its range to examine spatial patterns and determine whether specific diatom taxa were consistently associated with turtles (as occurs in the filamentous alga Basicladia spp...
2017: PloS One
https://www.readbyqxmd.com/read/28190954/prevalence-of-pre-pregnancy-obesity-2011-2014
#7
Laura Gregor, Patrick L Remington, Sara Lindberg, Deborah Ehrenthal
IMPORTANCE: Obesity before and during pregnancy increases risk among mothers for poor health outcomes, such as diabetes, high blood pressure, and cardiovascular disease. OBJECTIVE: To describe trends in pre-pregnancy obesity rates among women in Wisconsin. METHODS: Cross-sectional data from Wisconsin birth certificates were analyzed. Prevalence of pre-pregnancy obesity (defined as body mass index = 30) among Wisconsin women who gave birth from 2011 through 2014 was compared across demographic and geographic dimensions...
November 2016: WMJ: Official Publication of the State Medical Society of Wisconsin
https://www.readbyqxmd.com/read/28190953/development-of-an-obesity-prevention-dashboard-for-wisconsin
#8
Karissa Ryan, Parvathy Pillai, Patrick L Remington, Kristen Malecki, Sara Lindberg
IMPORTANCE: A comprehensive obesity surveillance system monitors obesity rates along with causes and related health policies, which are valuable for tracking and identifying problems needing intervention. METHODS: A statewide obesity dashboard was created using the County Health Rankings model. Indicators were obtained through publicly available secondary data sources and used to rank Wisconsin amongst other states on obesity rates, health factors, and policies...
November 2016: WMJ: Official Publication of the State Medical Society of Wisconsin
https://www.readbyqxmd.com/read/28181702/cerebrovascular-burden-and-depressive-symptomatology-interrelate-over-18%C3%A2-years-support-for-the-vascular-depression-hypothesis
#9
Rosanna Scott, Daniel Paulson
OBJECTIVE: Potentially incongruent research literatures suggest three divergent hypotheses about depressive symptomatology: (1) symptoms are recurrent; (2) later-life depression results from high cerebrovascular burden (CVB); and (3) depressive symptoms contribute to comorbidities causing vascular burden. Past vascular depression research assumes that later-life depressive symptoms relate uniquely to high CVB and not to prior, recurrent depression. This study examines these divergent hypotheses...
February 9, 2017: International Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/28177158/neuronal-responses-support-a-role-for-orbitofrontal-cortex-in-cognitive-set-reconfiguration
#10
Brianna J Sleezer, Giuliana Loconte, Meghan D Castagno, Benjamin Y Hayden
We are often faced with the need to abandon no-longer beneficial rules and adopt new ones. This process, known as cognitive set reconfiguration, is a hallmark of executive control. Although cognitive functions like reconfiguration are most often associated with dorsal prefrontal structures, recent evidence suggests that the orbitofrontal cortex (OFC) may play an important role as well. We recorded activity of OFC neurons while rhesus macaques performed an analogue of the Wisconsin Card Sorting Task that involved a trial-and-error stage...
February 8, 2017: European Journal of Neuroscience
https://www.readbyqxmd.com/read/28176615/identification-by-next-generation-sequencing-of-aichivirus-b-in-a-calf-with-enterocolitis-and-neurologic-signs
#11
Ana S D Moreira, Sarah M Raabis, Melissa E Graham, Jennifer M Dreyfus, Samuel D Sibley, Jennifer A Godhardt-Cooper, Kathy L Toohey-Kurth, Tony L Goldberg, Simon F Peek
An 11-d-old Holstein bull calf was presented to the Veterinary Medical Teaching Hospital at the University of Wisconsin-Madison because of a 4-d history of diarrhea and persistent low-grade fever. Initial diagnosis was enteritis caused by Cryptosporidium and rotavirus. During hospitalization, the calf became stuporous and was only responsive to noxious stimuli, with hypotonia of all 4 limbs, tail, head, and neck. A cerebrospinal fluid analysis revealed xanthochromia, with marked lymphocytic pleocytosis, which was suggestive of viral meningitis and/or encephalitis...
January 1, 2017: Journal of Veterinary Diagnostic Investigation
https://www.readbyqxmd.com/read/28160748/resting-state-eeg-gamma-power-and-theta-gamma-coupling-enhancement-following-high-frequency-left-dorsolateral-prefrontal-rtms-in-patients-with-depression
#12
Yoshihiro Noda, Reza Zomorrodi, Takashi Saeki, Tarek K Rajji, Daniel M Blumberger, Zafiris J Daskalakis, Motoaki Nakamura
OBJECTIVE: We aimed to investigate neuromodulatory effects of high-frequency left dorsolateral prefrontal cortex repetitive transcranial magnetic stimulation (rTMS) on resting-state electroencephalography (EEG) and their clinical and cognitive correlates in patients with depression. METHODS: Thirty-one patients diagnosed with depression included in the present study. Resting-state gamma power and theta-gamma coupling (TGC) were calculated before and after a course of rTMS...
January 9, 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/28159490/chemohormonal-therapy-in-metastatic-hormone-sensitive-prostate-cancer-sweeney-cj-chen-yh-carducci-m-liu-g-jarrard-df-eisenberger-m-wong-yn-hahn-n-kohli-m-cooney-mm-dreicer-r-vogelzang-nj-picus-j-shevrin-d-hussain-m-garcia-ja-dipaola-rs-department-of-medicine
#13
Eggener Scott
BACKGROUND: Androgen deprivation therapy (ADT) has been the backbone of treatment for metastatic prostate cancer since the 1940s. We assessed whether concomitant treatment with ADT plus docetaxel would result in longer overall survival than that with ADT alone. METHODS: We assigned men with metastatic, hormone-sensitive prostate cancer to receive either ADT plus docetaxel (at a dose of 75mg per square meter of body-surface area every 3wk for 6 cycles) or ADT alone...
March 2017: Urologic Oncology
https://www.readbyqxmd.com/read/28154790/sharing-local-public-health-services-across-jurisdictions-comparing-practice-in-2012-and-2014
#14
Kusuma Madamala, Susan Zahner, Roger Brown
OBJECTIVE: Describe cross-jurisdiction service sharing (CJS) by local and tribal health departments (LHD) in Wisconsin in 2014 compared to 2012. DESIGN: An online survey of 91 LHD directors in Wisconsin was conducted. Results were compared to the results of a 2012 survey. Characteristics of CJS arrangements and differences in results by population size, geographic region, and governance type were described. Standardized proportion differences (h) were estimated using the arcsin transformation...
April 2016: Frontiers in Public Health Services & Systems Research
https://www.readbyqxmd.com/read/28152806/reducing-patient-wait-time-on-an-inpatient-hematology-and-transplant-unit
#15
Rory Joseph Makielski, Kurt Osterby, Mike Fallon, Nicole Domask, Vicki Hubbard, Eva Allen, Blythe Gage, Gail Hettrick, Jessica Fischer, Andrew Brown, Brianna Grahn, Brett Welhouse, Hannah Draayers, Mark Juckett, Jean Ligocki, Ruth O'Regan, Laurie Kaufman
: 87 Background: The University of Wisconsin Hematology and Bone Marrow Transplant services admit 250 patients per year for scheduled treatment. Time from patient arrival to chemotherapy initiation averages 7 hours. This long time leads to patient dissatisfaction and prolonged length of stay. Chemotherapy often begins in the evening when physicians and pharmacists are not on site to clarify treatment questions. METHODS: A multidisciplinary team was formed in April 2015 as part of the ASCO Quality Training Program...
March 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28152763/multidisciplinary-optimization-of-oral-chemotherapy-delivery-at-the-uw-carbone-cancer-center
#16
Mary Mably, Jason Bergsbaken, Kari Schuhmacher, Chris Nemergut, Aaron Bohler, Jessica Fischer
: 58 Background: Use of oral chemotherapy is expanding and offers advantages but introduces unique safety challenges. ASCO and ONS addressed these issues with inclusion of oral chemotherapy in published chemotherapy administration safety standards. METHODS: The updated ASCO/ONS standards offered a framework for the University of Wisconsin Carbone Cancer Center to evaluate and improve our practice with the goal of full compliance with these standards. Gap analysis revealed noncompliance with five and partial compliance with eleven standards...
March 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28146230/a-framework-to-improve-surgeon-communication-in-high-stakes-surgical-decisions-best-case-worst-case
#17
Lauren J Taylor, Michael J Nabozny, Nicole M Steffens, Jennifer L Tucholka, Karen J Brasel, Sara K Johnson, Amy Zelenski, Paul J Rathouz, Qianqian Zhao, Kristine L Kwekkeboom, Toby C Campbell, Margaret L Schwarze
Importance: Although many older adults prefer to avoid burdensome interventions with limited ability to preserve their functional status, aggressive treatments, including surgery, are common near the end of life. Shared decision making is critical to achieve value-concordant treatment decisions and minimize unwanted care. However, communication in the acute inpatient setting is challenging. Objective: To evaluate the proof of concept of an intervention to teach surgeons to use the Best Case/Worst Case framework as a strategy to change surgeon communication and promote shared decision making during high-stakes surgical decisions...
February 1, 2017: JAMA Surgery
https://www.readbyqxmd.com/read/28139160/the-relation-between-sleep-disruption-and-cataract-in-a-large-population-based-study
#18
Yanjun Chen, David M Nondahl, Carla R Schubert, Barbara E K Klein, Ronald Klein, Karen J Cruickshanks
PURPOSE: To investigate the relation between sleep disruption and nuclear cataract, as well as the impact of cataract removal on sleep, in two discrete population-based cohorts. METHODS: This is a cross-sectional study of 5070 participants from three large longitudinal epidemiologic studies of age-related eye disease, hearing, olfaction, and cognition. Slit-lamp photos of the lens were obtained to grade nuclear cataract using a standardized protocol. The quality of sleep was assessed using a modified Wisconsin Sleep Cohort Study questionnaire...
January 31, 2017: Ophthalmic Epidemiology
https://www.readbyqxmd.com/read/28139144/embedded-performance-validity-testing-in-neuropsychological-assessment-potential-clinical-tools
#19
Tyler A Rickards, Christopher C Cranston, Pegah Touradji, Kathleen T Bechtold
The article aims to suggest clinically-useful tools in neuropsychological assessment for efficient use of embedded measures of performance validity. To accomplish this, we integrated available validity-related and statistical research from the literature, consensus statements, and survey-based data from practicing neuropsychologists. We provide recommendations for use of 1) Cutoffs for embedded performance validity tests including Reliable Digit Span, California Verbal Learning Test (Second Edition) Forced Choice Recognition, Rey-Osterrieth Complex Figure Test Combination Score, Wisconsin Card Sorting Test Failure to Maintain Set, and the Finger Tapping Test; 2) Selecting number of performance validity measures to administer in an assessment; and 3) Hypothetical clinical decision-making models for use of performance validity testing in a neuropsychological assessment collectively considering behavior, patient reporting, and data indicating invalid or noncredible performance...
January 31, 2017: Applied Neuropsychology. Adult
https://www.readbyqxmd.com/read/28135587/spatially-explicit-methodology-for-coordinated-manure-management-in-shared-watersheds
#20
Mahmoud Sharara, Apoorva Sampat, Laura W Good, Amanda S Smith, Pamela Porter, Victor M Zavala, Rebecca Larson, Troy Runge
Increased clustering and consolidation of livestock production systems has been linked to adverse impacts on water quality. This study presents a methodology to optimize manure management within a hydrologic region to minimize agricultural phosphorus (P) loss associated with winter manure application. Spatial and non-spatial data representing livestock, crop, soil, terrain and hydrography were compiled to determine manure P production rates, crop P uptake, existing manure storage capabilities, and transportation distances...
January 27, 2017: Journal of Environmental Management
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