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Hypertension in black

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https://www.readbyqxmd.com/read/29785962/age-related-blood-pressure-sensitivity-to-aldosterone-in-blacks-and-whites
#1
Wanzhu Tu, Ruohong Li, Vivek Bhalla, George J Eckert, J Howard Pratt
Aldosterone sensitivity, defined as the magnitude of the association of plasma aldosterone concentration with blood pressure (BP), seems to be a function of plasma volume. It increases as plasma renin activity decreases, and it is more significant in blacks but less so in whites. Age is a strong determinant of BP, and an increase in aldosterone sensitivity could contribute to the increase in BP. In the present study, we tested the hypothesis that aldosterone sensitivity increases with age. We used observational data collected from normotensive blacks and whites enrolled in a prospective cohort study...
May 21, 2018: Hypertension
https://www.readbyqxmd.com/read/29777021/serum-6-bromotryptophan-levels-identified-as-a-risk-factor-for-ckd-progression
#2
Adrienne Tin, Girish Nadkarni, Anne M Evans, Cheryl A Winkler, Erwin Bottinger, Casey M Rebholz, Mark J Sarnak, Lesley A Inker, Andrew S Levey, Michael S Lipkowitz, Lawrence J Appel, Dan E Arking, Josef Coresh, Morgan E Grams
Background Metabolite levels reflect physiologic homeostasis and may serve as biomarkers of disease progression. Identifying metabolites associated with APOL1 risk alleles-genetic variants associated with CKD risk commonly present in persons of African descent-may reveal novel markers of CKD progression relevant to other populations. Methods We evaluated associations between the number of APOL1 risk alleles and 760 serum metabolites identified via untargeted profiling in participants of the African American Study of Kidney Disease and Hypertension (AASK) ( n =588; Bonferroni significance threshold P <6...
May 18, 2018: Journal of the American Society of Nephrology: JASN
https://www.readbyqxmd.com/read/29776622/sleep-deficiency-among-native-hawaiian-pacific-islander-black-and-white-americans-and-the-association-with-cardiometabolic-diseases-analysis-of-the-national-health-interview-survey-data
#3
Ellyn E Matthews, Chenghui Li, Christopher R Long, Marie-Rachelle Narcisse, Bradley C Martin, Pearl Anna McElfish
PURPOSE: Examine sleep deficiency, factors, and associations with cardiometabolic diseases in United States Native Hawaiian/Pacific Islanders (NHPI), Blacks, and Whites. DESIGN: Data from the 2014 National Health Interview Survey and NHPI National Health Interview Survey household interviews of adults were analyzed. PARTICIPANTS: Of 31,724 participants, 7% were NHPI, 14% were Black, and 79% were White. METHODS: Habitual sleep duration and quality, sociodemographic/economic covariates, health behaviors, psychological distress, and chronic diseases were self-reported...
June 2018: Sleep Health
https://www.readbyqxmd.com/read/29769083/racial-ethnic-disparities-among-asian-americans-in-inpatient-acute-myocardial-infarction-mortality-in-the-united-states
#4
Eun Ji Kim, Nancy R Kressin, Michael K Paasche-Orlow, Lenny Lopez, Jennifer E Rosen, Mengyun Lin, Amresh D Hanchate
BACKGROUND: Acute myocardial infarction (AMI) is a common high-risk disease with inpatient mortality of 5% nationally. But little is known about this outcome among Asian Americans (Asians), a fast growing racial/ethnic minority in the country. The objectives of the study are to obtain near-national estimates of differences in AMI inpatient mortality between minorities (including Asians) and non-Hispanic Whites and identify comorbidities and sociodemographic characteristics associated with these differences...
May 16, 2018: BMC Health Services Research
https://www.readbyqxmd.com/read/29761548/variation-of-carotid-intima-media-thickness-with-body-mass-index-in-healthy-adults-of-black-african-descent
#5
Adesola Abiodun Asaleye, Kolawole Thomas Braimoh, Olalekan Ibukun Oyinloye, Christianah Mopelola Asaleye, Adeleye Dorcas Omisore
OBJECTIVES: Studies have shown that common carotid intima media thickness (CIMT) measured by B-mode sonography increases with body mass index (BMI) among subjects with cardiovascular diseases in different populations. However, association of body fat and subclinical atherosclerosis in the absence of these cardiovascular diseases is understudied. We aimed to evaluate the correlation between BMI and CIMT in a healthy adult population of black African ancestry. METHODS: This is a cross-sectional prospective study in 300 consecutive apparently healthy subjects aged 18 to 70 years without history of hypertension, dyslipidemia, diabetes mellitus, and renal disease...
May 15, 2018: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/29754732/-hypertension-in-black-patients
#6
O Steichen, A Atallah, J-M Halimi, D Herpin, J Inamo, A Kané, J-J Monsuez, J-J Mourad
No abstract text is available yet for this article.
May 2018: Journal de Médecine Vasculaire
https://www.readbyqxmd.com/read/29753799/predictors-of-erectile-function-normalization-in-men-with-erectile-dysfunction-treated-with-placebo
#7
John P Mulhall, Martin Carlsson, Vera Stecher, Li-Jung Tseng
BACKGROUND: Clinical study and practice data have shown sildenafil improves sexual function in men with erectile dysfunction (ED). However, some men treated with placebo in double-blind, placebo-controlled sildenafil studies also report improved erectile function as measured by International Index of Erectile Function (IIEF)-Erectile Function Domain (EFD) scores. AIM: This analysis estimated the relationship between post-baseline IIEF-EFD scores and demographic variables, including co-morbidities, in men with ED receiving placebo in flexible-dose sildenafil studies...
May 9, 2018: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/29753617/patient-factors-associated-with-prolonged-postoperative-opioid-use-after-total-knee-arthroplasty
#8
Robert S Namba, Anshuman Singh, Elizabeth W Paxton, Maria C S Inacio
BACKGROUND: Pain persists in a moderate proportion of patients after total knee arthroplasty (TKA). Identifying patient factors that are associated with persistent pain may lead to improved care. PURPOSE: The purpose of the study was to identify preoperative factors associated with increased opioid prescriptions after TKA. METHODS: A retrospective cohort study of TKAs in an integrated health-care system (January 2008-December 2011) was conducted...
April 9, 2018: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29746317/stroke-incidence-is-highest-in-women-and-non-hispanic-blacks-living-with-hiv-in-the-aids-clinical-trials-group-longitudinal-linked-randomized-trials-cohort
#9
Felicia C Chow, Michael R Wilson, Kunling Wu, Ronald J Ellis, Ronald J Bosch, Benjamin P Linas
OBJECTIVE: To investigate the incidence of first-ever stroke/transient ischemic attack (TIA) and associated risk factors in a cohort of persons living with HIV infection (PLWH). DESIGN: Observational cohort study METHODS:: We determined incidence rates of first-ever stroke/TIA in PLWH after ART initiation from the AIDS Clinical Trials Group ALLRT cohort and its parent trials. Poisson regression models evaluated baseline and time-varying covariates as risk factors for stroke/TIA...
June 1, 2018: AIDS
https://www.readbyqxmd.com/read/29741952/partnering-medical-students-with-barbers-to-cut-hypertension-in-black-men
#10
Yoonhee P Ha, Leah D Seifu, Lisa M Lewis, Roxanne Dupuis, Bridgette M Brawner, Carolyn C Cannuscio
No abstract text is available yet for this article.
June 2018: American Journal of Public Health
https://www.readbyqxmd.com/read/29738558/inflammatory-signatures-distinguish-metabolic-health-in-african-american-women-with-obesity
#11
Gerald V Denis, Paola Sebastiani, Kimberly A Bertrand, Katherine J Strissel, Anna H Tran, Jaromir Slama, Nilton D Medina, Guillaume Andrieu, Julie R Palmer
Obesity-driven Type 2 diabetes (T2D) is a systemic inflammatory condition associated with cardiovascular disease. However, plasma cytokines and tissue inflammation that discriminate T2D risk in African American women with obese phenotypes are not well understood. We analyzed 64 circulating cytokines and chemokines in plasma of 120 African American women enrolled in the Black Women's Health Study. We used regression analysis to identify cytokines and chemokines associated with obesity, co-morbid T2D and hypertension, and compared results to obese women without these co-morbidities, as well as to lean women without the co-morbidities...
2018: PloS One
https://www.readbyqxmd.com/read/29737180/copeptin-to-rule-out-myocardial-infarction-in-blacks-versus-caucasians
#12
Neil Beri, Lori B Daniels, Allan Jaffe, Christian Mueller, Inder Anand, W Frank Peacock, Judd E Hollander, Christopher DeFilippi, Donald Schreiber, James McCord, Alexander T Limkakeng, Alan H B Wu, Fred S Apple, Deborah B Diercks, John T Nagurney, Richard M Nowak, Chad M Cannon, Paul Clopton, Sean-Xavier Neath, Robert H Christenson, Christopher Hogan, Gary Vilke, Alan Maisel
BACKGROUND: Copeptin in combination with troponin has been shown to have incremental value for the early rule-out of myocardial infarction, but its performance in Black patients specifically has never been examined. In light of a potential for wider use, data on copeptin in different relevant cohorts are needed. This is the first study to determine whether copeptin is equally effective at ruling out myocardial infarction in Black and Caucasian races. METHODS: This analysis of the CHOPIN trial included 792 Black and 1075 Caucasian patients who presented to the emergency department with chest pain and had troponin-I and copeptin levels drawn...
May 1, 2018: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/29736755/racial-and-ethnic-disparities-in-diagnosis-of-chronic-medical-conditions-in-the-usa
#13
Eun Ji Kim, Taekyu Kim, Joseph Conigliaro, Jane M Liebschutz, Michael K Paasche-Orlow, Amresh D Hanchate
BACKGROUND: There exist racial and ethnic disparities in the prevalence of chronic medical illnesses. However, it is unclear if the disparities arise from patients' self-reported estimates on these diseases and whether there is an association between healthcare utilization and diagnosis. OBJECTIVE: To estimate national racial/ethnic prevalence of undiagnosed hypertension, diabetes, high cholesterol, and kidney disease and identify characteristics associated with undiagnosed diseases...
May 7, 2018: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/29735310/factors-leading-to-the-discard-of-deceased-donor-kidneys-in-the-united-states
#14
Sumit Mohan, Mariana C Chiles, Rachel E Patzer, Stephen O Pastan, S Ali Husain, Dustin J Carpenter, Geoffrey K Dube, R John Crew, Lloyd E Ratner, David J Cohen
The proportion of deceased donor kidneys procured for transplant but subsequently discarded has been growing steadily in the United States, but factors contributing to the rising discard rate remain unclear. To assess the reasons for and probability of organ discard we assembled a cohort of 212,305 deceased donor kidneys recovered for transplant from 2000-2015 in the SRTR registry that included 36,700 kidneys that were discarded. 'Biopsy Findings' (38.2%) was the most commonly reported reason for discard. The median Kidney Donor Risk Index of discarded kidneys was significantly higher than transplanted organs (1...
May 5, 2018: Kidney International
https://www.readbyqxmd.com/read/29722843/diet-quality-among-us-born-and-foreign-born-non-hispanic-blacks-nhanes-2003-2012-data
#15
Alison G M Brown, Robert F Houser, Josiemer Mattei, Colin D Rehm, Dariush Mozaffarian, Alice H Lichtenstein, Sara C Folta
Background: Non-Hispanic blacks in the United States are less likely to not meet national dietary recommendations than non-Hispanic whites; however, most studies do not consider nativity of US blacks. Objective: With the use of the Alternative Healthy Eating Index-2010 (AHEI-2010) and the Dietary Approach to Stop Hypertension (DASH) scores, this cross-sectional study compared diet quality between US-born (n = 3,911) and foreign-born (n = 408) non-Hispanic black adults aged 22-79 y, based on pooled nationally representative data (NHANES 2003-2012) as well as by length of US residency...
May 1, 2018: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29716476/high-reintervention-and-amputation-rates-after-outpatient-atherectomy-for-claudication
#16
Dipankar Mukherjee, Brian Contos, Erica Emery, Devon T Collins, James H Black
Outpatient use of atherectomy for peripheral arterial disease has grown rapidly and outcomes are poorly understood. We analyzed outcomes of atherectomy done for claudication, comparing office and hospital outpatient settings. Analysis of Medicare Part B claims data was performed for incident femoral-popliteal or tibial-peroneal atherectomy from 2012 to 2014. Longitudinal analysis assessed services 18 months before, during, and up to 18 months after the incident peripheral vascular intervention (PVI). Differences between office-based and hospital outpatient-based settings were assessed using χ2 and Fisher exact tests...
January 1, 2018: Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/29712737/fgf23-fibroblast-growth-factor-23-and-incident-hypertension-in-young-and-middle-aged-adults-the-cardia-study-coronary-artery-risk-development-in-young-adults
#17
Ehimare Akhabue, Samantha Montag, Jared P Reis, Lindsay R Pool, Rupal Mehta, Clyde W Yancy, Lihui Zhao, Myles Wolf, Orlando M Gutierrez, Mercedes R Carnethon, Tamara Isakova
Blacks have the highest prevalence of hypertension in the United States. Higher levels of FGF23 (fibroblast growth factor-23) have been associated with worse cardiovascular outcomes. Whether FGF23 is associated with rising blood pressure (BP) and racial differences in incident hypertension is unclear. We studied 1758 adults (45.0±3.7 years; 57.8% female; 36.9% black) without hypertension or cardiovascular disease who participated in the year 20 (2005-2006) follow-up examination of the CARDIA study (Coronary Artery Risk Development in Young Adults)...
April 30, 2018: Hypertension
https://www.readbyqxmd.com/read/29710289/association-of-a-smartphone-application-with-medication-adherence-and-blood-pressure-control-the-medisafe-bp-randomized-clinical-trial
#18
Kyle Morawski, Roya Ghazinouri, Alexis Krumme, Julie C Lauffenburger, Zhigang Lu, Erin Durfee, Leslie Oley, Jessica Lee, Namita Mohta, Nancy Haff, Jessie L Juusola, Niteesh K Choudhry
Importance: Medication nonadherence accounts for up to half of uncontrolled hypertension. Smartphone applications (apps) that aim to improve adherence are widely available but have not been rigorously evaluated. Objective: To determine if the Medisafe smartphone app improves self-reported medication adherence and blood pressure control. Design, Setting, and Participants: This was a 2-arm, randomized clinical trial (Medication Adherence Improvement Support App For Engagement-Blood Pressure [MedISAFE-BP])...
April 16, 2018: JAMA Internal Medicine
https://www.readbyqxmd.com/read/29707388/risk-factors-and-co-morbidities-associated-with-changes-in-renal-function-among-antiretroviral-treatment-na%C3%A3-ve-adults-in-south-africa-a-chart-review
#19
Shirelle Assaram, Tivani P Mashamba-Thompson, Nombulelo P Magula
Introduction: Our systematic scoping review has demonstrated a research gap in antiretroviral treatment (ART) nephrotoxicity as well as in the long-term outcomes of renal function for patients on ART in South Africa. Bearing in mind the high prevalence of human immunodeficiency virus (HIV) in South Africa, this is of great concern. Objectives: To determine the risk factors and co-morbidities associated with changes in renal function in HIV-infected adults in South Africa...
2018: Southern African Journal of HIV Medicine
https://www.readbyqxmd.com/read/29699915/dyslipidemia-is-associated-with-pediatric-nonalcoholic-fatty-liver-disease
#20
Shima Dowla, Stella Aslibekyan, Amy Goss, Kevin Fontaine, Ambika P Ashraf
BACKGROUND: With the increasing prevalence of childhood obesity, nonalcoholic fatty liver disease (NAFLD) has emerged as the most common cause of pediatric chronic liver disorder. Factors underlying the pathophysiology of NAFLD remain poorly defined. OBJECTIVE: This study aimed to describe the metabolic characteristics of children with NAFLD differing in race/ethnicity and to test associations between dyslipidemia and NAFLD. METHODS: A retrospective chart review was conducted at a tertiary referral university hospital among 309 children with a diagnosis of NAFLD...
April 3, 2018: Journal of Clinical Lipidology
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