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hemoglobin monitoring

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https://www.readbyqxmd.com/read/29149240/z-scores-based-methods-and-their-application-to-biological-monitoring-an-example-in-professional-soccer-players
#1
Guillaume Saulière, Jérôme Dedecker, Laurie-Anne Marquet, Pierre Rochcongar, Jean-Francois Toussaint, Geoffroy Berthelot
The clinical and biological follow-up of individuals, such as the biological passport for athletes, is typically based on the individual and longitudinal monitoring of hematological or urine markers. These follow-ups aim to identify abnormal behavior by comparing the individual's biological samples to an established baseline. These comparisons may be done via different ways, but each of them requires an appropriate extra population to compute the significance levels, which is a non-trivial issue. Moreover, it is not necessarily relevant to compare the measures of a biomarker of a professional athlete to that of a reference population (even restricted to other athletes), and a reasonable alternative is to detect the abnormal values by considering only the other measurements of the same athlete...
November 15, 2017: Biostatistics
https://www.readbyqxmd.com/read/29146451/effect-of-rate-of-administration-of-propofol-or-alfaxalone-on-induction-dose-requirements-and-occurrence-of-apnea-in-dogs
#2
Sarah E Bigby, Thierry Beths, Sébastien Bauquier, Jennifer E Carter
OBJECTIVE: To evaluate the effect of rate of administration of propofol or alfaxalone on induction dose requirements and incidence of postinduction apnea (PIA) in dogs following premedication with methadone and dexmedetomidine. STUDY DESIGN: Prospective, randomized clinical trial. ANIMALS: Thirty-two healthy American Society of Anesthesiologists class I client-owned dogs (seven females, 25 males), aged between 5 and 54 months, weighing between 2...
May 2, 2017: Veterinary Anaesthesia and Analgesia
https://www.readbyqxmd.com/read/29145467/adenosine-lidocaine-and-mg2-alm-fluid-therapy-attenuates-systemic-inflammation-platelet-dysfunction-and-coagulopathy-after-non-compressible-truncal-hemorrhage
#3
Hayley Letson, Geoffrey Dobson
BACKGROUND: Systemic inflammation and coagulopathy are major drivers of injury progression following hemorrhagic trauma. Our aim was to examine the effect of small-volume 3% NaCl adenosine, lidocaine and Mg2+ (ALM) bolus and 0.9% NaCl/ALM 'drip' on inflammation and coagulation in a rat model of hemorrhagic shock. METHODS: Sprague-Dawley rats (429±4 g) were randomly assigned to: 1) shams, 2) no-treatment, 3) saline-controls, 4) ALM-therapy, and 5) Hextend®. Hemorrhage was induced in anesthetized-ventilated animals by liver resection (60% left lateral lobe and 50% medial lobe)...
2017: PloS One
https://www.readbyqxmd.com/read/29144814/self-blood-glucose-monitoring-underestimates-hyperglycemia-and-hypoglycemia-as-compared-to-continuous-glucose-monitoring-in-type-1-and-type-2-diabetes
#4
Devna Mangrola, Christine Cox, Arianne S Furman, Sridevi Krishnan, Sidika E Karakas
OBJECTIVE: When glucose records from self-blood glucose monitoring (SBGM) do not reflect estimated average glucose from HgBA1, or when patients' clinical symptoms are not explained by their SBGM records, clinical management of diabetes becomes a challenge. Our objective was to determine the magnitude of differences in glucose values reported by SBGM vs. documented by continuous glucose monitoring (CGM). METHODS: The CGM was conducted by a clinical diabetes educator/registered nurse by the clinic protocol, using the Medtronic iPRO2™ system...
November 16, 2017: Endocrine Practice
https://www.readbyqxmd.com/read/29144813/diagnosing-and-monitoring-endocrine-dysfunction-diabetes-and-obesity-in-a-cohort-of-adult-survivors-of-childhood-cancer
#5
Victoria Rollins Hudspeth, Stuart Harrison Gold, David Robert Clemmons
OBJECTIVE: 5-year survival for childhood cancer has increased to 80%, resulting in a growing population of adult survivors of childhood cancer (ASOCC). Long-term endocrine dysfunction is as high as 63% when screened in research protocols. The purpose of this study was to evaluate the prevalence of endocrine testing, endocrine dysfunction, diabetes, obesity, and endocrinologist visits outside of a research screening protocol. METHODS: Retrospective chart review was performed for 176 ASOCC who were diagnosed with cancer before age 18, followed at least 10 years, were now at least 18, and had survived to the time of chart review...
November 16, 2017: Endocrine Practice
https://www.readbyqxmd.com/read/29142807/silver-nanoparticle-human-hemoglobin-interface-time-evolution-of-the-corona-formation-and-interaction-phenomenon
#6
A K Bhunia, T Kamilya, S Saha
In this paper, we have used spectroscopic and electron microscopic analysis to monitor the time evolution of the silver nanoparticles (Ag NP)-human hemoglobin (Hb) corona formation and to characterize the interaction of the Ag NPs with Hb. The time constants for surface plasmon resonance binding and reorganization are found to be 9.51 and 118.48 min, respectively. The drop of surface charge and the increase of the hydrodynamic diameter indicated the corona of Hb on the Ag NP surface. The auto correlation function is found to broaden with the increasing time of the corona formation...
2017: Nano Convergence
https://www.readbyqxmd.com/read/29139301/design-of-a-24-week-trial-of-empagliflozin-once-daily-in-hypertensive-black-african-american-patients-with-type-2-diabetes-mellitus
#7
Keith C Ferdinand, Leo Seman, Afshin Salsali
OBJECTIVE: Black/African American patients have higher prevalence of type 2 diabetes mellitus (T2DM), diabetes-related complications, and hypertension, but they are often underrepresented in clinical trials. The sodium-glucose co-transporter 2 inhibitor, empagliflozin, was associated with significant improvements in glucose control (via hemoglobin [Hb] A1c) and reductions in blood pressure (BP; via office and ambulatory BP monitoring) in a primarily white population with T2DM and hypertension...
November 15, 2017: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/29136023/modifications-of-hemoglobin-and-myoglobin-by-maillard-reaction-products-mrps
#8
Aristos Ioannou, Constantinos Varotsis
High performance liquid chromatography (HPLC) coupled with a Fraction Collector was employed to isolate Maillard reaction products (MRPs) formed in model systems comprising of asparagine and monosaccharides in the 60-180°C range. The primary MRP which is detected at 60°C is important for Acrylamide content and color/aroma development in foods and also in the field of food biotechnology for controlling the extent of the Maillard reaction with temperature. The discrete fractions of the reaction products were reacted with Hemoglobin (Hb) and Myoglobin (Mb) at physiological conditions and the reaction adducts were monitored by UV-vis and Attenuated Total Reflection-Fourier transform infrared (FTIR) spectrophotometry...
2017: PloS One
https://www.readbyqxmd.com/read/29134657/mechanisms-involved-in-hemoglobin-mediated-oxidation-of-lipids-in-washed-fish-muscle-and-inhibitory-effects-of-phospholipase-a2
#9
Nantawat Tatiyaborworntham, Mark P Richards
BACKGROUND: Hemoglobin is a lipid oxidation promoter in fish muscle. Phospholipase A2 (PLA2; EC 3.1.1.4), is linked to increased resistance to lipid oxidation of frozen-thawed cod fillets via an unknown mechanism. The aims of this study were to investigate the mechanism of hemoglobin-mediated lipid oxidation with a focus on ferryl hemoglobin and methemoglobin, the pro-oxidative hemoglobin species, and to examine how porcine pancreatic PLA2 inhibits hemoglobin-mediated lipid oxidation in washed cod muscle (WCM)...
November 13, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/29132740/effects-of-using-symbiotics-in-the-clinical-nutritional-evolution-of-patients-with-chronic-pancreatitis-study-prospective-randomized-controlled-double-blind
#10
Patricia Quadros Dos Santos, Jorge C Guedes, Rosangela P de Jesus, Raquel Rocha Dos Santos, Rosemeiri L Fiaconne
Patients with chronic pancreatitis (CP) present malabsorption and changes in nutritional status. In this prospective, randomized, controlled, double-blinded, intervention study, developed at the Clinic of Pancreas, we aimed to assess whether the use of symbiotics changes the nutritional status, the biochemical data and the intestinal rate of these patients. The intervention consisted of administering 12 g/day of symbiotics composed of Lactobacillus casei, Lactobacillus rhamnosus, Lactobacillus acidophilus, Bifidobacterium bifidum and fructooligosaccharides to the intervention group and 12 g/day of medium absorption complex carbohydrate to the control group...
April 2017: Clinical Nutrition ESPEN
https://www.readbyqxmd.com/read/29111029/hematoma-volume-is-a-predictive-factor-of-disturbed-autoregulation-after-spontaneous-intracerebral-hemorrhage
#11
Hongyin Ma, Zhen-Ni Guo, Xin Sun, Jia Liu, Shan Lv, Lu Zhao, Weitong Guo, Hang Jin, Yi Yang
BACKGROUND: Dynamic cerebral autoregulation (dCA) is probably disturbed after spontaneous intracerebral hemorrhage (ICH) and could be an independent predictor of clinical outcome. Clinical determinants of dCA status after ICH need to be further elucidated. METHODS: We finally enrolled 53 patients diagnosed with supratentorial ICH within 6days from onset. DCA was assessed 4-6days after ICH onset by monitoring middle cerebral artery blood flow velocities and simultaneous arterial blood pressure continuously, utilizing transcranial Doppler combined with a servo-controlled finger plethysmograph...
November 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/29106815/high-dose-glucocorticoids-treatment-does-not-induce-severe-hyperglycemia-in-young-patients-with-autoimmune-diseases-by-cgms
#12
Ying Zhou, Yan Zhao, Tao Yuan, Nan Jiang, Yingyue Dong, Yunjiao Yang, Li Wang, Jiuliang Zhao, Le Min, Weigang Zhao
INTRODUCTION: High-dose glucocorticoids (HDG) are used in the treatment of autoimmune diseases. Glucocorticoids-induced hyperglycemia (GIH) is often described in elderly patients. In young patients with autoimmune diseases, however, the risk for GIH has not been well characterized. METHODS: Twenty-four inpatients (median age 32 years (interquatile range 25-42)) with exacerbations of autoimmune diseases, receiving 1-2mg/kg/day prednisone or equivalent methylprednisone, were recruited...
November 6, 2017: Endocrine Practice
https://www.readbyqxmd.com/read/29101675/red-blood-cell-distribution-width-a-potential-laboratory-parameter-for-monitoring-inflammation-in-rheumatoid-arthritis
#13
Yujue He, Can Liu, Zhiyong Zeng, Weilin Ye, Jinpiao Lin, Qishui Ou
Correlation analysis of red blood cell distribution width (RDW) and C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), tumor necrosis factor α (TNF-α), interleukin (IL)-6, and IL-10 in rheumatoid arthritis (RA) to investigate whether RDW can serve as a potential parameter for indicating inflammation in RA patients. A total of 670 RA patients from October 2014 to April 2016 were enrolled in our study. The white blood cell (WBC), red blood cell (RBC), platelet (PLT), hemoglobin (HGB), RDW, CRP, and ESR in peripheral blood of patients with RA were retrospectively analyzed...
November 3, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/29101207/the-ferroportin-disease-pathogenesis-diagnosis-and-treatment
#14
Antonello Pietrangelo
The Ferroportin Disease is an autosomal dominant hereditary iron loading disorder associated with heterozygote mutations of the ferroportin-1 (FPN) gene. It represents one of commonest cause of genetic hyperferritinemia, regardless of ethnicity. FPN1 transfers iron from the intestine, macrophages and placenta into the bloodstream. In the ferroportin disease, loss-of-function mutations of FPN1 limit but do not impair iron-export in enterocytes, but severely affects iron-transfer in macrophages. This leads to progressive and preferential iron trapping in tissue macrophages, reduced iron release to serum transferrin (i...
November 3, 2017: Haematologica
https://www.readbyqxmd.com/read/29099626/contribution-of-structured-self-monitoring-of-blood-glucose-to-the-glycemic-control-and-the-quality-of-life-in-both-insulin-and-noninsulin-treated-patients-with-poorly-controlled-diabetes
#15
Kai Kan, Wei Zhu, Fengdi Lu, Yun Shen, Fei Gao, Yifei Mo, Xingxing He, Yuqian Bao, Jian Zhou, Weiping Jia
BACKGROUND: The rate of glycemic control among diabetes patients in China is currently low. The current study aims at determining the effect of structured self-monitoring of blood glucose (SMBG) on blood glucose control as well as quality of life (QoL) in Chinese diabetes patients. METHODS: In a 24-week, single-center, randomized, open-label, prospective trial, patients with glycated hemoglobin A1c (HbA1c) >8.0% were randomized to an intervention group for structured SMBG (n = 121) or a control group (n = 129)...
November 3, 2017: Diabetes Technology & Therapeutics
https://www.readbyqxmd.com/read/29098110/sex-related-differences-in-hematological-parameters-and-organosomatic-indices-of-oreochromis-niloticus-exposed-to-aflatoxin-b1-diet
#16
Esther Marijani, Johnson Nasimolo, Emmanuel Kigadye, Gbemenou Joselin Benoit Gnonlonfin, Sheila Okoth
A 24-week feeding experiment was conducted to assess whether males and females of Oreochromis niloticus exhibit differences in their hematological responses and organosomatic indices to dietary AFB1 contamination. Triplicate groups of O. niloticus (initial body weight: 24.1 ± 0.6 g) were fed with four diets (Diets 1 to 4) containing 0, 20, 200, and 2,000 μg AFB1 kg(-1). A significant decrease (P < 0.05) in hemoglobin (Hb), red blood cells (RBC), and hematocrit (Hct) was observed in AFB1 exposure groups, with the lowest levels recorded in the 2000 μg AFB1 kg(-1) treatment...
2017: Scientifica
https://www.readbyqxmd.com/read/29098096/hbs-sicilian-%C3%AE-%C3%AE-0-thalassemia-a-rare-variant-of-sickle-cell
#17
Grace Onimoe, Genine Smarzo
Sickle cell disease (SCD) is caused by a mutation in the sixth codon of the β-globin gene on chromosome 11, which leads to a single amino acid substitution (glutamine to valine). Sickle-(δβ)(0)-thalassemia is a rare variant of sickle cell disease (delta-beta thalassemia occurring in association with sickle hemoglobin, HbS), sparsely reported in literature, and has been associated with symptomatology necessitating careful monitoring and follow-up. We describe a patient who presented with a newborn screen reported as "FS" and a negative family history for sickle cell disease and sickle cell trait...
2017: Case Reports in Hematology
https://www.readbyqxmd.com/read/29090977/observational-registry-of-basal-insulin-treatment-in-patients-with-type-2-diabetes-in-china-safety-and-hypoglycemia-predictors
#18
Tingting Zhang, Linong Ji, Yan Gao, Puhong Zhang, Dongshan Zhu, Xian Li, Jiachao Ji, Fang Zhao, Heng Zhang, Xiaohui Guo
BACKGROUND: The Observational Registry of Basal Insulin Treatment (ORBIT) study evaluated the safety of basal insulin (BI) in real-world settings in China. METHODS: We analyzed 9002 patients with type 2 diabetes (T2D) inadequately controlled with oral hypoglycemic agents from 8 geographic regions and 2 hospital tiers in China who initiated and maintained BI treatment. Body weight and hypoglycemic episodes were recorded at baseline and 3 and 6 months. Serious adverse events (SAEs) were recorded at 3 and 6 months...
November 2017: Diabetes Technology & Therapeutics
https://www.readbyqxmd.com/read/29090247/perioperative-red-blood-cell-transfusion-in-orofacial-surgery
#19
REVIEW
So-Young Park, Kwang-Suk Seo, Myong-Hwan Karm
In the field of orofacial surgery, a red blood cell transfusion (RBCT) is occasionally required during double jaw and oral cancer surgery. However, the question remains whether the effect of RBCT during the perioperative period is beneficial or harmful. The answer to this question remains challenging. In the field of orofacial surgery, transfusion is performed for the purpose of oxygen transfer to hypoxic tissues and plasma volume expansion when there is bleeding. However, there are various risks, such as infectious complications (viral and bacterial), transfusion-related acute lung injury, ABO and non-ABO associated hemolytic transfusion reactions, febrile non-hemolytic transfusion reactions, transfusion associated graft-versus-host disease, transfusion associated circulatory overload, and hypersensitivity transfusion reaction including anaphylaxis and transfusion-related immune-modulation...
September 2017: J Dent Anesth Pain Med
https://www.readbyqxmd.com/read/29089659/basics-of-monitoring-equipment
#20
REVIEW
Tanya Duke-Novakovski
Monitoring equipment has become reliable and affordable for use in general veterinary practice. This article provides a guide to technology, troubleshooting, and obtaining quality data using 4 non-invasive techniques that are commonly used in practice. Pulse oximetry estimates oxygen saturation of hemoglobin in arterial blood, capnography measures the carbon dioxide content of inspired and expired gas, and either Doppler shift detection or oscillometry can be used to measure blood pressure. These useful non-invasive techniques all rely on adequate perfusion of the tissues for optimum function...
November 2017: Canadian Veterinary Journal. la Revue Vétérinaire Canadienne
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