Xiaoxiang Gao, Xiangjun Chen, Hongjie Hu, Xinyu Wang, Wentong Yue, Jing Mu, Zhiyuan Lou, Ruiqi Zhang, Keren Shi, Xue Chen, Muyang Lin, Baiyan Qi, Sai Zhou, Chengchangfeng Lu, Yue Gu, Xinyi Yang, Hong Ding, Yangzhi Zhu, Hao Huang, Yuxiang Ma, Mohan Li, Aditya Mishra, Joseph Wang, Sheng Xu
Electronic patches, based on various mechanisms, allow continuous and noninvasive monitoring of biomolecules on the skin surface. However, to date, such devices are unable to sense biomolecules in deep tissues, which have a stronger and faster correlation with the human physiological status than those on the skin surface. Here, we demonstrate a photoacoustic patch for three-dimensional (3D) mapping of hemoglobin in deep tissues. This photoacoustic patch integrates an array of ultrasonic transducers and vertical-cavity surface-emitting laser (VCSEL) diodes on a common soft substrate...
December 15, 2022: Nature Communications