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Jing Zhou, Yi Han
OBJECTIVES: To analyze the ability of pleth variability index (PVI) and respiratory system compliance (RSC) on evaluating the hemodynamic and respiratory effects of positive end expiratory pressure (PEEP), then to direct PEEP settings in mechanically ventilated critical patients. METHODS: We studied 22 mechanically ventilated critical patients in the intensive care unit. Patients were monitored with classical monitor and a pulse co-oximeter, with pulse sensors attached to patients' index fingers...
2016: SpringerPlus
Elizabeth Bridges, Jennifer J Hatzfeld
OBJECTIVE: To describe the accuracy and precision of noninvasive hemoglobin measurement (SpHb) compared with laboratory or point-of-care Hb, and SpHb ability to trend in seriously injured casualties. METHODS: Observational study in a convenience sample of combat casualties undergoing resuscitation at two US military trauma hospitals in Afghanistan. SpHb was obtained using the Masimo Rainbow SET (Probe Rev E/Radical-7 Pulse CO-Oximeter v Clinically indicated Hb was analyzed with a Coulter or iStat and compared with simultaneous SpHb values...
September 2016: Shock
P H Huang, B F Shih, Y-F Tsai, P C H Chung, F C Liu, H P Yu, W C Lee, C J Chang, C C Lin
BACKGROUND: Shift in large fluid volumes and massive blood loss during liver transplantation frequently leads to rapid changes in hemoglobin (Hb) concentration; thus, to ensure adequate tissue oxygenation, accurate and rapid determination of Hb concentration is essential in transplant recipients. The Radical-7 Pulse CO-Oximeter provides a noninvasive and continuous way to monitor Hb concentration (SpHb) in real time and is an ideal candidate for use during liver transplantation. In this study, we assessed the relationship between SpHb and total Hb (tHb) obtained from arterial blood samples during surgery...
May 2016: Transplantation Proceedings
Tsuyoshi Isosu, Shinju Obara, Takahiro Hakozaki, Tsuyoshi Imaizumi, Yuzo Iseki, Midori Mogami, Satoshi Ohashi, Yukihiro Ikegami, Shin Kurosawa, Masahiro Murakawa
The effects of intravenous injection of indigo carmine on noninvasive and continuous total hemoglobin (SpHb) measurement were retrospectively evaluated with the Revision L sensor. The subjects were 18 patients who underwent elective gynecologic surgery under general anesthesia. During surgery, 5 mL of 0.4 % indigo carmine was injected intravenously, and changes in SpHb concentrations between before and after the injection were evaluated. The mean age was 52.4 ± 12.8 years. Before injection, the median SpHb level was 10...
February 22, 2016: Journal of Clinical Monitoring and Computing
T Damén, B Reinsfelt, B Redfors, A Nygren
BACKGROUND: Induction of general anaesthesia has been shown to cause haemodilution and an increase in plasma volume. The aim of this study was to evaluate whether prevention of hypotension during anaesthesia induction could avoid haemodilution. METHODS: Twenty-four cardiac surgery patients, 66 ± 10 years, were randomised to receive either norepinephrine in a dose needed to maintain mean arterial blood pressure (MAP) at pre-anaesthesia levels after induction or to a control group that received vasopressor if MAP decreased below 60 mmHg...
May 2016: Acta Anaesthesiologica Scandinavica
Werner Baulig, Burkhardt Seifert, Donat R Spahn, Oliver M Theusinger
The Masimo Radical-7 Pulse CO-Oximeter (Masimo Corp., USA) non-invasively computes hemoglobin concentration (SpHb). SpHb was compared to Co-Oximeter readings (CoOxHb) of arterial samples in surgery patients of the emergency department. Forty-six patients were enrolled. The Masimo R1 25L (revision F and G) adult adhesive sensor was attached to the ring finger of the arterially cannulated hand. Before start, every 30 min during surgery and in the case of severe bleeding SpHb and CoOxHb values were documented...
December 19, 2015: Journal of Clinical Monitoring and Computing
Shiming Yang, Peter F Hu, Amechi Anazodo, Cheng Gao, Hegang Chen, Christine Wade, Lauren Hartsky, Catriona Miller, Cristina Imle, Raymond Fang, Colin F Mackenzie
BACKGROUND: A noninvasive decision support tool for emergency transfusion would benefit triage and resuscitation. We tested whether 15 minutes of continuous pulse oximetry-derived hemoglobin measurements (SpHb) predict emergency blood transfusion better than conventional oximetry, vital signs, and invasive point-of-admission (POA) laboratory testing. We hypothesized that the trends in noninvasive SpHb features monitored for 15 minutes predict emergency transfusion better than pulse oximetry, shock index (SI = heart rate/systolic blood pressure), or routine POA laboratory measures...
January 2016: Anesthesia and Analgesia
Aditya Bhat, Amit Upadhyay, Vijay Jaiswal, Deepak Chawla, Dharamveer Singh, Mithilesh Kumar, C P Yadav
UNLABELLED: This study was conducted at a tertiary care center in northern India to evaluate the validity of non-invasive transcutaneous hemoglobin estimation in healthy and sick children in comparison to hemoglobin estimation by traditional lab method. A method comparison study was conducted including 150 subjects. Enrolled patients included 80 neonates with average age of 3.9 ± 2.1 days, and 70 children with average age of 5.8 ± 2 years. Each population (newborn and children) comprised of almost equal numbers of healthy and critically ill patients with shock...
February 2016: European Journal of Pediatrics
Seul Gi Park, Oh Haeng Lee, Yong-Hee Park, Hwa Yong Shin, Hyun Kang, Chong Wha Baek, Yong Hun Jung, Young Cheol Woo
BACKGROUND: We hypothesized that induction of general anesthesia using sevoflurane improves the accuracy of non-invasive hemoglobin (SpHb) measurement of Masimo Radical-7® Pulse CO-Oximetry by inducing peripheral vasodilation and increasing the perfusion index (PI). The aim of this study is to investigate the change in the SpHb and the PI measured by Rad7 during induction of general anesthesia using sevoflurane. METHODS: The laboratory hemoglobin (Hblab) was measured before surgery by venous blood sampling...
August 2015: Korean Journal of Anesthesiology
Eva Wittenmeier, Sophia Bellosevich, Susanne Mauff, Irene Schmidtmann, Michael Eli, Gunther Pestel, Ruediger R Noppens
INTRODUCTION: Collecting a blood sample is usually necessary to measure hemoglobin levels in children. Especially in small children, noninvasively measuring the hemoglobin level could be extraordinarily helpful, but its precision and accuracy in the clinical environment remain unclear. In this study, noninvasive hemoglobin measurement and blood gas analysis were compared to hemoglobin measurement in a clinical laboratory. METHODS: In 60 healthy preoperative children (0...
October 2015: Paediatric Anaesthesia
Stavros G Memtsoudis, Thomas Danninger, Ottokar Stundner, Daniel Yoo, Federico P Girardi, Friedrich Boettner, Isabelle Kao, Kara G Fields, Michael K Urban, Stephen O Heard, J Matthias Walz
BACKGROUND: Traditionally, blood transfusions in the perioperative setting are used to maintain adequate delivery of nutrients and oxygen to organs. However, the effect of blood administration on tissue oxygenation in the perioperative setting remains poorly understood. QUESTIONS/PURPOSES: The aim of this study was to determine changes in muscle tissue oxygenation saturation (SmO2) in response to perioperative blood transfusions. PATIENTS AND METHODS: Patients undergoing total knee arthroplasty were enrolled...
July 2015: HSS Journal: the Musculoskeletal Journal of Hospital for Special Surgery
Tsuyoshi Isosu, Tomohiko Satoh, Rieko Oishi, Tsuyoshi Imaizumi, Takahiro Hakozaki, Shinju Obara, Yukihiro Ikegami, Shin Kurosawa, Masahiro Murakawa
The effects of an intravenous injection of indigo carmine on noninvasive and continuous total hemoglobin (SpHb) measurement were retrospectively evaluated. The subjects were 21 patients who underwent elective gynecologic surgery under general anesthesia. During surgery, 5 mL of 0.4 % indigo carmine was intravenously injected, and subsequent changes in SpHb concentrations were evaluated. The results demonstrate that the pre-injection SpHb level was 10 g/dL, and the minimum post-injection SpHb level was 8...
June 2016: Journal of Clinical Monitoring and Computing
Samuel M Galvagno, Peter Hu, Shiming Yang, Cheng Gao, David Hanna, Stacy Shackelford, Colin Mackenzie
Early detection of hemorrhagic shock is required to facilitate prompt coordination of blood component therapy delivery to the bedside and to expedite performance of lifesaving interventions. Standard physical findings and vital signs are difficult to measure during the acute resuscitation stage, and these measures are often inaccurate until patients deteriorate to a state of decompensated shock. The aim of this study is to examine a severely injured trauma patient population to determine whether a noninvasive SpHb monitor can predict the need for urgent blood transfusion (universal donor or additional urgent blood transfusion) during the first 12 h of trauma patient resuscitation...
December 2015: Journal of Clinical Monitoring and Computing
C Nicholas, R George, S Sardesai, M Durand, R Ramanathan, R Cayabyab
OBJECTIVE: To describe the accuracy of noninvasive hemoglobin (Hb) obtained with pulse co-oximeter (SpHb) compared with total Hb (tHb) from laboratory co-oximeter in neonates. STUDY DESIGN: Neonates with birth weight (BW) <3000 g admitted to LAC+USC Medical Center neonatal intensive care unit were included. SpHb was recorded using Masimo Radical-7 and compared with tHb. A total of three data sets were obtained for each patient. Regression analysis and Bland-Altman analysis were performed...
August 2015: Journal of Perinatology: Official Journal of the California Perinatal Association
Michael R Phillips, Amal L Khoury, Andrey V Bortsov, Amy Marzinsky, Kathy A Short, Bruce A Cairns, Anthony G Charles, Benny L Joyner, Sean E McLean
BACKGROUND: Critically ill pediatric patients frequently require hemoglobin monitoring. Accurate noninvasive Hb (SpHb) would allow practitioners to decrease anemia from repeated blood draws, traumatic blood draws, and a decreased number of laboratory Hb (LabHb) medical tests. The Food and Drug Administration has approved the Masimo Pronto SpHb and associated Rainbow probes; however, its use in the pediatric intensive care unit (PICU) is controversial. In this study, we define the degree of agreement between LabHb and SpHb using the Masimo Pronto SpHb Monitor and identify clinical and demographic conditions associated with decreased accuracy...
May 1, 2015: Journal of Surgical Research
D Frasca, H Mounios, B Giraud, M Boisson, B Debaene, O Mimoz
Non-invasive monitoring of haemoglobin concentration provides real-time measurement of haemoglobin concentration (SpHb) using multi-wavelength pulse co-oximetry. We hypothesised that in-vivo adjustment using the mean of three haemoglobinometer (HemoCue®) measurements from an arterial blood sample at the first SpHb measurement (HCueART) would increase the accuracy of the monitor. The study included 41 adults for a total of 173 measurements of haemoglobin concentration. In-vivo adjusted SpHb was automatically calculated by the following formula: in-vivo adjusted SpHb = unadjusted SpHb - (SpHb - HCueART)...
July 2015: Anaesthesia
Wael N Awada, Maher F Mohmoued, Tarek M Radwan, Gomaa Z Hussien, Hany W Elkady
Continuous, noninvasive hemoglobin (SpHb) monitoring provides clinicians with the trending of changes in hemoglobin, which has the potential to alter red blood cell transfusion decision making. The objective of this study was to evaluate the impact of SpHb monitoring on blood transfusions in high blood loss surgery. In this prospective cohort study, eligible patients scheduled for neurosurgery were enrolled into either a Control Group or an intervention group (SpHb Group). The Control Group received intraoperative hemoglobin monitoring by intermittent blood sampling when there was an estimated 15% blood loss...
December 2015: Journal of Clinical Monitoring and Computing
Nicole Ribeiro Marques, George C Kramer, Richard Benjamin Voigt, Michael G Salter, Michael P Kinsky
Automated critical care systems for en route care will rely heavily on noninvasive continuous monitoring. It has been reported that noninvasive assessment of blood hemoglobin via CO-oximetry (SpHb) assessed by spot measurements lacks sufficient accuracy for clinical decision making in trauma patients. However, the precision and utility of trending of continuous hemoglobin have not been evaluated in hemorrhaging humans. This study measured the trending and concordance of SpHb changes during dynamic variations resulting from controlled hemorrhage with concomitant fluid infusion...
August 2015: Shock
A A Khalafallah, C R Chilvers, M Thomas, C M Chilvers, M Sexton, M Vialle, I K Robertson
BACKGROUND: Delay in diagnosis of anaemia during preoperative assessment poses logistic problems, leading to multiple clinic visits, inadequate preoperative management, and unnecessary delay of surgery. Therefore, we tested an instant spectrophotometric haemoglobin (SpHb) measurement technique to facilitate this assessment. METHODS: We evaluated portable instant SpHb vs standard laboratory screening of anaemia between March 2012 and December 2013. Paired Hb measurements were performed on 726 patients using SpHb (Pronto-7, Masimo Corporation, Irvine, CA, USA) and Hb measured on the same day using an automated analyser...
April 2015: British Journal of Anaesthesia
Ken Yamaura, Noriko Nanishi, Midoriko Higashi, Sumio Hoka
STUDY OBJECTIVE: To validate intraoperative pulse hemoglobin (SpHb) measurements in anesthetized patients with large forearm temperature - fingertip temperature gradients. DESIGN: prospective and observational study. SETTING: Operating room of a university hospital. PATIENTS: 28 patients undergoing surgery during general anesthesia, requiring arterial blood withdrawal. INTERVENTIONS: Radial arterial blood pressure, forearm and fingertip skin surface temperatures, and SpHb were monitored...
December 2014: Journal of Clinical Anesthesia
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