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https://www.readbyqxmd.com/read/28074875/from-an-indirect-response-pharmacodynamic-model-towards-a-secondary-signal-model-of-dose-response-relationship-between-exercise-training-and-physical-performance
#1
Thierry Busso
The aim of this study was to test the suitability of using indirect responses for modeling the effects of physical training on performance. We formulated four different models assuming that increase in performance results of the transformation of a signal secondary to the primary stimulus which is the training dose. The models were designed to be used with experimental data with daily training amounts ascribed to input and performance measured at several dates ascribed to output. The models were tested using data obtained from six subjects who trained on a cycle ergometer over a 15-week period...
January 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28061004/objective-physical-and-mental-markers-of-self-reported-fatigue-in-women-undergoing-neo-adjuvant-chemotherapy-for-early-stage-breast-cancer
#2
Joanne E Mortimer, Sarah Waliany, Christina M Dieli-Conwright, Sunita K Patel, Arti Hurria, Joseph Chao, Brian Tiep, Carolyn E Behrendt
BACKGROUND: Objective, treatment-independent markers of cancer-related fatigue are needed to advance clinical trials. In the current study, the authors evaluated physical, neurocognitive, and serologic markers for correlation with self-reported fatigue before and after (neo)adjuvant chemotherapy for patients with early-stage breast cancer. METHODS: Women with AJCC TNM Stage I-III breast cancer consented to assessment before and after the completion of 4 cycles of dose-dense doxorubicin and cyclophosphamide...
January 6, 2017: Cancer
https://www.readbyqxmd.com/read/28050921/influence-of-dietary-acid-load-on-exercise-performance
#3
Catherine Applegate, Mackenzie Mueller, Krystle E Zuniga
Diet composition can affect systemic pH and acid-base regulation, which may in turn influence exercise performance. An acidic environment in the muscle impairs performance and contributes to fatigue; therefore, current trends in sports nutrition place importance on maximizing the alkalinity of the body with ergogenic aids and dietary strategies. This review examines the evidence on the effects of dietary manipulations on acid load and exercise performance. Ten studies that investigated the effect of high versus low dietary acid loads on athletic performance generally identified that low dietary acid loads increased plasma pH, but did not consistently improve exercise performance at maximal or submaximal exercise intensities...
January 4, 2017: International Journal of Sport Nutrition and Exercise Metabolism
https://www.readbyqxmd.com/read/28033123/accuracy-of-a-modified-lactate-minimum-test-and-reverse-lactate-threshold-test-to-determine-maximal-lactate-steady-state
#4
Patrick Wahl, Christian Manunzio, Florian Vogt, Sarah Strütt, Prisca Volmary, Wilhelm Bloch, Joachim Mester
This study evaluated the accuracy of a modified-lactate-minimum-test (mLMT), a modified-reverse-lactate-threshold-test (mRLT), in comparison to two established threshold concepts (OBLA & mDmax) to determine power output at maximal-lactate-steady-state (MLSS) in cycling. Nineteen subjects performed an mLMT, an mRLT, a graded-exercise-test (100W start, +20W every 3 min) and 3 or more constant-load tests of 30 minutes to determine power output at MLSS. The mLMT and mRLT both consisted of an initial lactate priming-segment, followed by a short recovery phase...
December 20, 2016: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28029290/high-resolution-melting-analysis-for-detection-of-a-single-nucleotide-polymorphism-and-the-genotype-of-the-myostatin-gene-in-warmblood-horses
#5
Priscila B S Serpa, Petra Garbade, Cláudio C Natalini, Ananda R Pires, Tainor M Tisotti
OBJECTIVE To develop a high-resolution melting (HRM) assay to detect the g.66493737C>T polymorphism in the myostatin gene (MSTN) and determine the frequency of 3 previously defined g.66493737 genotypes (T/T, T/C, and C/C) in warmblood horses. SAMPLES Blood samples from 23 horses. PROCEDURES From each blood sample, DNA was extracted and analyzed by standard PCR methods and an HRM assay to determine the MSTN genotype. Three protocols (standard protocol, protocol in which a high-salt solution was added to the reaction mixture before the first melting cycle, and protocol in which an unlabeled probe was added to the reaction mixture before analysis) for the HRM assay were designed and compared...
January 2017: American Journal of Veterinary Research
https://www.readbyqxmd.com/read/28018241/master-athletes-are-extending-the-limits-of-human-endurance
#6
REVIEW
Romuald Lepers, Paul J Stapley
The increased participation of master athletes (i.e., >40 years old) in endurance and ultra-endurance events (>6 h duration) over the past few decades has been accompanied by an improvement in their performances at a much faster rate than their younger counterparts. Aging does however result in a decrease in overall endurance performance. Such age-related declines in performance depend upon the modes of locomotion, event duration, and gender of the participant. For example, smaller age-related declines in cycling performance than in running and swimming have been documented...
2016: Frontiers in Physiology
https://www.readbyqxmd.com/read/28009787/prevalence-of-exercise-induced-arterial-hypoxemia-in-distance-runners-at-sea-level
#7
Keren Constantini, David A Tanner, Timothy P Gavin, Craig A Harms, Joel M Stager, Robert F Chapman
PURPOSE: It has been reported that ~50% of endurance-trained men demonstrate exercise induced arterial oxyhemoglobin hypoxemia (EIAH) during heavy exercise. However, this often-cited prevalence rate comes from a single study using a cohort of 25 highly trained men who completed maximal cycle ergometry. As arterial oxyhemoglobin saturation (SpO2) during maximal exercise is reported to be significantly lower during treadmill vs. cycle ergometry in the same subjects, we hypothesized that the prevalence of EIAH would be greater than previously reported (and commonly referenced) in a larger cohort of highly endurance-trained men during maximal treadmill running...
December 22, 2016: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/27997257/solid-gel-and-liquid-carbohydrate-format-effects-on-gut-comfort-and-performance
#8
Mathilde Guillochon, David S Rowlands
Carbohydrate sports drinks produce worthwhile benefits to endurance performance compared with non-caloric controls. However, athletes now consume carbohydrate in a range of formats, including gels and bars, but the comparable performance outcomes are unknown. Therefore, the aim of this study was to establish the relative effects of drink, gel, bar, and mixed carbohydrate formats on intense cycling performance. In a treatment-apparent randomised crossover design, 12 well-trained male cyclists completed 4 trials comprising a 140-min race simulation, followed by a double-blind slow-ramp to exhaustion (0...
December 20, 2016: International Journal of Sport Nutrition and Exercise Metabolism
https://www.readbyqxmd.com/read/27994554/effect-of-environmental-and-feedback-interventions-on-pacing-profiles-in-cycling-a-meta-analysis
#9
REVIEW
Michael J Davies, Bradley Clark, Marijke Welvaert, Sabrina Skorski, Laura A Garvican-Lewis, Philo Saunders, Kevin G Thompson
In search of their optimal performance athletes will alter their pacing strategy according to intrinsic and extrinsic physiological, psychological and environmental factors. However, the effect of some of these variables on pacing and exercise performance remains somewhat unclear. Therefore, the aim of this meta-analysis was to provide an overview as to how manipulation of different extrinsic factors affects pacing strategy and exercise performance. Only self-paced exercise studies that provided control and intervention group(s), reported trial variance for power output, disclosed the type of feedback received or withheld, and where time-trial power output data could be segmented into start, middle and end sections; were included in the meta-analysis...
2016: Frontiers in Physiology
https://www.readbyqxmd.com/read/27974154/in-air-versus-underwater-comparison-of-3d-reconstruction-accuracy-using-action-sport-cameras
#10
Gustavo R D Bernardina, Pietro Cerveri, Ricardo M L Barros, João C B Marins, Amanda P Silvatti
Action sport cameras (ASC) have achieved a large consensus for recreational purposes due to ongoing cost decrease, image resolution and frame rate increase, along with plug-and-play usability. Consequently, they have been recently considered for sport gesture studies and quantitative athletic performance evaluation. In this paper, we evaluated the potential of two ASCs (GoPro Hero3+) for in-air (laboratory) and underwater (swimming pool) three-dimensional (3D) motion analysis as a function of different camera setups involving the acquisition frequency, image resolution and field of view...
January 25, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/27967282/whole-body-vibration-increases-subsequent-sprint-performance-in-well-trained-cyclists
#11
Bent R Rønnestad, Gunnar Slettaløkken Falch, Stian Ellefsen
PURPOSE: Postactivation potentiation (PAP) exercise with added whole-body vibration (WBV) has been suggested as a potential way to acutely improve sprint performance. In cycling, there are many competitions and situations where sprinting abilities are important. In the present study we investigated the effect of adding WBV to warm-up procedures on subsequent cycle sprint performance. METHODS: Eleven well-trained cyclists participated in the study. All cyclists performed a familiarization session before two separate test sessions in randomized order...
December 14, 2016: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/27936120/sweat-facilitated-amino-acid-losses-in-male-athletes-during-exercise-at-32-34%C3%A2-c
#12
R Hugh Dunstan, Diane L Sparkes, Benjamin J Dascombe, Margaret M Macdonald, Craig A Evans, Christopher J Stevens, Marcus J Crompton, Johan Gottfries, Jesse Franks, Grace Murphy, Ryan Wood, Timothy K Roberts
Sweat contains amino acids and electrolytes derived from plasma and athletes can lose 1-2L of sweat per hour during exercise. Sweat may also contain contributions of amino acids as well as urea, sodium and potassium from the natural moisturizing factors (NMF) produced in the stratum corneum. In preliminary experiments, one participant was tested on three separate occasions to compare sweat composition with surface water washings from the same area of skin to assess contributions from NMF. Two participants performed a 40 minute self-paced cycle session with sweat collected from cleansed skin at regular intervals to assess the contributions to the sweat load from NMF over the period of exercise...
2016: PloS One
https://www.readbyqxmd.com/read/27918666/quantification-of-training-and-competition-loads-in-endurance-sports-methods-and-applications
#13
Iñigo Mujika
Training quantification is basic to evaluate an endurance athlete's responses to the training loads, ensure adequate stress/recovery balance and determine the relationship between training and performance. Quantifying both external and internal workload is important, because the external workload does not measure the biological stress imposed by the exercise sessions. Generally used quantification methods include retrospective questionnaires, diaries, direct observation and physiological monitoring, often based on the measurement of oxygen uptake, heart rate and blood lactate concentration...
December 5, 2016: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/27913948/branched-chain-amino-acids-administration-suppresses-endurance-exercise-related-activation-of-ubiquitin-proteasome-signaling-in-trained-human-skeletal-muscle
#14
Evgeny A Lysenko, Tatiana F Vepkhvadze, Egor M Lednev, Olga L Vinogradova, Daniil V Popov
We tested whether post exercise ingestion of branched-chain amino acids (BCAA < 10 g) is sufficient to activate signaling associated with muscle protein synthesis and suppress exercise-induced activation of mechanisms associated with proteolysis in endurance-trained human skeletal muscle. Nine endurance-trained athletes performed a cycling bout with and without BCAA ingestion (0.1 g/kg). Post exercise ACC(Ser79/222) phosphorylation (endogenous marker of AMPK activity) was increased (~3-fold, P < 0...
December 3, 2016: Journal of Physiological Sciences: JPS
https://www.readbyqxmd.com/read/27904629/effect-of-various-kinds-of-beverages-on-stress-oxidative-f2-isoprostane-serum-lipid-and-blood-glucose-of-elite-taekwondo-players
#15
Zahra Maghsoudi, Ashfin Shiranian, Gholamreza Askai, Reza Ghaisvand
BACKGROUND: Athletes' recovery is important in improving their performance. Nutritional strategies can be effective in enhancing recovery rate. Choosing the best food items in appropriate intervals can play effective roles in resynthesis of fuels and recovery of muscle injury. Beverage micro and macronutrient content are helpful in fuel restoration. In this study, we assess the effects of various kinds of beverages on oxidative stress, muscle injury, and metabolic risk factors in taekwondo players...
September 2016: Iranian Journal of Nursing and Midwifery Research
https://www.readbyqxmd.com/read/27857844/analysis-of-the-pushing-phase-in-paralympic-cross-country-sit-skiers-class-lw10
#16
Laura Gastaldi, Stefano Mauro, Stefano Pastorelli
Paralympic Cross-Country sit-skiers use adaptive equipment, with a resulting gesture similar to double poling techniques adopted by able-bodied skiers. Despite the similarity, a specific attention on the gesture performed by sit-skiers is needed. The paper focuses on the sledge kinematic and on inertia effect of upper body motion which is translated in a propulsive effect in the early stage of the pushing cycle. In particular a group of 7 elite sit skiers of class LW10 were recorded with a video-based markerless motion capture technique during 1 km sprint Paralympic race...
November 2016: Journal of Advanced Research
https://www.readbyqxmd.com/read/27834554/subjective-fatigue-and-readiness-to-train-may-predict-functional-overreaching-after-only-3-days-of-cycling
#17
Twan Ten Haaf, Selma van Staveren, Erik Oudenhoven, Maria F Piacentini, Romain Meeusen, Bart Roelands, Leo Koenderman, Hein A M Daanen, Carl Foster, Jos J de Koning
PURPOSE: The aim of this study was to investigate whether monitoring of easily measurable stressors and symptoms can be used to early distinguish between acute fatigue (AF) and functional overreaching (FOR). METHODS: The study included 30 subjects (11 female/ 19 male, age: 40.8±10.8 y, VO2max: 51.8±6.3 ml/kg/min) who participated in an 8-day cycling event over 1,300 km with 18,500 climbing meters. Performance was measured before and after the event using a maximal incremental test...
November 11, 2016: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/27817192/positive-pacing-in-elite-ironman-triathletes
#18
Nicole Angehrn, Christoph A. Rüst, Pantelis T. Nikolaidis, Thomas Rosemann, Beat Knechtle
Pacing is known to influence athletic performance. For the Ironman triathlon program, a positive pacing strategy, i.e., the continuous decrease of speed over time was recommended. By analyzing split times, we assessed the pacing strategies of the top 100 finishers of the cycling part of 13 Ironman races and of the running part of 11 Ironman races taking place in 2014. Furthermore, sex-associated differences in performance and pacing strategies were calculated. We analyzed 7,687 cycling and 11,894 running split times of 1,392 triathletes (1,263 men, 129 women)...
31, 2016: Chinese Journal of Physiology
https://www.readbyqxmd.com/read/27813046/the-association-between-mct1-t1470a-polymorphism-and-power-oriented-athletic-performance
#19
N Kikuchi, N Fuku, R Matsumoto, S Matsumoto, H Murakami, M Miyachi, K Nakazato
The purpose of this study was to investigate the effects of the MCT1 T1470A polymorphism (rs1049434) on power-oriented performance and lactate concentration during or after cycling sprints in Japanese wrestlers. Participants (199 wrestlers and 649 controls) were genotyped for the MCT1 T1470A genotype (rs1049434) using the TaqMan(®) Assay. All wrestlers were international (n=77) or national (n=122) level athletes. Among them, 46 wrestlers performed 2 anaerobic performance tests, a 30-s Wingate Anaerobic test (WAnT) and a series of 10 maximal effort 10-s sprints on a cycle ergometer...
January 2017: International Journal of Sports Medicine
https://www.readbyqxmd.com/read/27798029/stress-fracture-and-premenstrual-syndrome-in-japanese-adolescent-athletes-a-cross-sectional-study
#20
Takashi Takeda, Yoko Imoto, Hiroyo Nagasawa, Atsuko Takeshita, Masami Shiina
OBJECTIVES: To investigate the relationship between the occurrence of stress fracture and premenstrual syndrome (PMS)/premenstrual dysphoric disorder (PMDD) in Japanese adolescent athletes. DESIGN: Cross-sectional study. SETTING: Osaka, Japan. PARTICIPANTS: A school-based survey on menstruation and school life was conducted using a sample of 1818 Japanese female students who belonged to two public high schools in Japan...
October 18, 2016: BMJ Open
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