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cervix cancer diagnosis

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https://www.readbyqxmd.com/read/29290072/operations-for-suspected-neoplasms-in-a-resource-limited-setting-experience-and-challenges-in-the-eastern-democratic-of-congo
#1
Luc Malemo Kalisya, Jacques Fadhili Bake, Richard Bigabwa, David H Rothstein, Sarah B Cairo
INTRODUCTION: Surgery is an essential component of a functional health system, with surgical conditions accounting for nearly 11-15% of world disability. While communicable diseases continue to burden low- and low-middle-income countries, non-communicable diseases, such as cancer, are an important cause of morbidity and mortality worldwide. Preliminary data on malignancies in low- and middle-income countries, specifically in Africa, suggest a higher mortality compared to other regions of the world, a difference partially explained by limited availability of screening and early detection systems as well as poorer access to treatment...
December 31, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/29286611/descriptive-epidemiology-of-cancers-in-togo-from-2009-to-2016
#2
Tchin Darre, Tchilabalo M Kpatcha, Aklesso Bagny, Nidain Maneh, Faré Gnandi-Piou, Boyodi Tchangai, Sassil Daré, Solange Adani-Ifé, Atchi Walla, Koffi Amégbor, Gado Napo-Koura
Background: Cancer is a global public health problem. According to World Report on Cancer in 2000, developing countries are becoming increasingly affected. Methods: This retrospective and descriptive 8-year study of all histological confirmed cancers was conducted using data from the anatomical pathology laboratory registry of Togo’s only laboratory. The parameters were frequency, site and histological type as well as age and gender. Results: We found 1,738 cancers in patients aged from 4 months to 109 years (mean, 50...
December 29, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/29225779/risk-of-solid-cancer-in-patients-with-mast-cell-activation-syndrome-results-from-germany-and-usa
#3
Gerhard J Molderings, Thomas Zienkiewicz, Jürgen Homann, Markus Menzen, Lawrence B Afrin
Background:  It has been shown repeatedly that mast cells can promote or prevent cancer development and growth. If development and/or progression of a solid cancer is substantially influenced by mast cell activity, the frequencies of occurrence of solid cancers in patients with primary mast cells disorders would be expected to differ from the corresponding prevalence data in the general population. In fact, a recent study demonstrated that patients with systemic mastocytosis (i.e., a rare neoplastic variant of the primary mast cell activation disease) have increased risk for solid cancers, in particular melanoma and non-melanoma skin cancers...
2017: F1000Research
https://www.readbyqxmd.com/read/29213225/role-of-blue-dye-for-sentinel-lymph-node-detection-in-early-endometrial-cancer
#4
Stefano Restaino, Carlo Ronsini, Angelo Finelli, Emanuele Perrone, Giovanni Scambia, Francesco Fanfani
Background: Sentinel Lymphonode analysis has become a barely new and innovative way to treat early stages of endometrial cancer (Ballester et al., Lancet Oncol 469-476, 2011; Buda et al., Ann Surg Oncol 2975-81, 2016). Indocyanine green cervical injection is considered gold standard for mapping nodes' drainage. Blue dye is used as a valid alternative in many centers, due to the lower cost of execution. The objective of this video is to prove that methylene blue dye's cervical injection is a valid and "low-cost" method to obtain mapping of lymphatic drainage in patient with early endometrial cancer...
2017: Gynecological Surgery
https://www.readbyqxmd.com/read/29192747/-situational-diagnosis-of-cancer-care-at-the-instituto-mexicano-del-seguro-social
#5
Sonia Patricia de Santillana-Hernández, María Teresa García-Flores, Héctor Galván-Oseguera, Gilberto Pérez-Rodríguez, Héctor David Martínez-Chapaca
Cancer is a public health problem with an impact on Health Services in Mexico; it is also, one of the leading causes of mortality (mortality rate: 610.6 / 100 000) and is expected to double the total number of new cases by 2035 (GLOBOCAN). The most frequent neoplasms are the malignant tumor of breast, prostate, cervix and uterin, colorectal and pulmonary. The most affected groups are the female, and by age the 65 years and older (INEGI). At the IMSS, the mortality rate for malignant tumors has varied, with a sustained decline since 2010...
2017: Revista Médica del Instituto Mexicano del Seguro Social
https://www.readbyqxmd.com/read/29186937/how-to-use-pet-ct-in-the-evaluation-of-response-to-radiotherapy
#6
Pierre Decazes, Sébastien Thureau, Bernard Dubray, Pierre Vera
INTRODUCTION: Radiotherapy is a major treatment modality for many cancers. Tumor response after radiotherapy determines the subsequent steps of the patient's management (surveillance, adjuvant or salvage treatment and palliative care). Tumor response assessed during radiotherapy offers a promising opportunity to adapt the treatment plan to reduced / increased target volume, to specifically target sub-volumes with relevant biological characteristics (metabolism, hypoxia, proliferation ...
November 28, 2017: Quarterly Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/29186874/do-cervical-cancer-patients-diagnosed-with-opportunistic-screening-live-longer-an-arkhangelsk-cancer-registry-study
#7
Elena E Roik, Evert Nieboer, Olga A Kharkova, Andrej M Grjibovski, Vitaly A Postoev, Jon Ø Odland
The aim of the current study was to compare cervical cancer (СС) patients diagnosed with and without screening in terms of: (i) sociodemographic and clinical characteristics; (ii) factors associated with survival; and (iii), and levels of risk. A registry-based study was conducted using data from the Arkhangelsk Cancer Registry. It included women with newly diagnosed malignant neoplasm of the uterine cervix during the period of 1 January 2005 to 11 November 2016 (N = 1548). The Kaplan-Meier method, the log-rank test, and Cox regression were applied...
November 26, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29179875/surgical-staging-identified-false-hpv-negative-cases-in-a-large-series-of-invasive-cervical-cancers
#8
Karl Ulrich Petry, Clemens Liebrich, Alexander Luyten, Martina Zander, Thomas Iftner
OBJECTIVE: We examined a large series of biopsy-proven invasive cervical cancers with surgical staging and HPV re-testing to estimate the relevance of HPV-negative cervical cancers in a Caucasian population. METHODS: We prospectively collected smears from 371 patients with a biopsy-proven diagnosis of cervical cancer for HC2 testing of high-risk HPV (HR-HPV). In HC2-negative cases, smears and paraffin embedded tissue blocks underwent additional HPV genotyping. RESULTS: HC2 tests showed 31/371 cases (8...
December 2017: Papillomavirus Research
https://www.readbyqxmd.com/read/29118475/histological-follow-up-in-patients-with-atypical-glandular-cells-on-pap-smears
#9
Gokhan Boyraz, Derman Basaran, Mehmet Coskun Salman, Akbar Ibrahimov, Sevgen Onder, Orkun Akman, Nejat Ozgul, Kunter Yuce
Context: Atypical glandular cells (AGCs) result in the Papanicolaou (Pap) smear may be associated with significant genital and nongenital neoplastic processes. Aims: To evaluate the underlying histopathology in women who had AGCs on Pap smears. Settings and Design: Retrospective cross-sectional study. Patients and Methods: Clinicopathological data of patients who had AGC on Pap smears and underwent histological workup between January 2004 and December 2014 were retrieved from the computerized database of a tertiary care center...
October 2017: Journal of Cytology
https://www.readbyqxmd.com/read/29115079/disparities-by-age-sex-tumor-stage-diagnosis-path-and-area-level-socioeconomic-status-in-survival-time-for-major-cancers-results-from-the-busan-cancer-registry
#10
Minjung Kwak, Changhoon Kim
Our goal was to examine the effect of area-level deprivation on patient survival time for seven major cancers - stomach, colon, liver, lung, breast, cervix, and thyroid cancer. Data on 10,902 subjects who were diagnosed with major cancers from 2010 and 2011 in Busan were collected regarding the survival time along with several important prognostic factors and an area-level deprivation index was constructed from education, income, unemployment, and welfare assistance, to assess the comprehensive area-level socioeconomic status...
December 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/29071810/cancer-registry-follow-up-for-17%C3%A2-million-person-years-of-a-nationwide-maternity-cohort
#11
Matti Lehtinen, Heljä-Marja Surcel, Kari Natunen, Eero Pukkala, Joakim Dillner
Population-based Finnish Maternity Cohort (FMC) comprises 2M first trimester sera collected from 1M women during 33 years. Informed consent is by the opt-out principle, and linkages with cancer and population registries provide a base for over time and over generation studies. Follow-up for 17M person-years by the end of 2014 can identify 39,700 cases of invasive cancer and 18,900 cases of premalignant breast and cervix lesions, and basal cell carcinoma diagnosed after serum sampling. For women with multiple pregnancies, serial samples taken before cancer diagnosis are available...
October 25, 2017: Cancer Medicine
https://www.readbyqxmd.com/read/29065867/the-relative-risk-of-second-primary-cancers-in-austria-s-western-states-a-retrospective-cohort-study
#12
Oliver Preyer, Nicole Concin, Andreas Obermair, Hans Concin, Hanno Ulmer, Willi Oberaigner
BACKGROUND: Cancer survivors are at risk of developing a second primary cancer (SPC) later in life because of persisting effects of genetic and behavioural risk factors, the long-term sequelae of chemotherapy, radiotherapy and the passage of time. This is the first study with Austrian data on an array of entities, estimating the risk of SPCs in a population-based study by calculating standardized incidence ratios (SIRs). METHODS: This retrospective cohort study included all invasive incident cancer cases diagnosed within the years 1988 to 2005 being registered in the Tyrol and Vorarlberg Cancer Registries...
October 24, 2017: BMC Cancer
https://www.readbyqxmd.com/read/29046833/optical-techniques-for-cervical-neoplasia-detection
#13
REVIEW
Tatiana Novikova
This paper provides an overview of the current research in the field of optical techniques for cervical neoplasia detection and covers a wide range of the existing and emerging technologies. Using colposcopy, a visual inspection of the uterine cervix with a colposcope (a binocular microscope with 3- to 15-fold magnification), has proven to be an efficient approach for the detection of invasive cancer. Nevertheless, the development of a reliable and cost-effective technique for the identification of precancerous lesions, confined to the epithelium (cervical intraepithelial neoplasia) still remains a challenging problem...
2017: Beilstein Journal of Nanotechnology
https://www.readbyqxmd.com/read/29042887/the-prevalence-of-depression-among-patients-with-the-top-ten-most-common-cancers-in-south-korea
#14
Boram Park, Soyoung Youn, Ki-Kyung Yi, Su-Yeon Lee, Jung-Sun Lee, Seockhoon Chung
OBJECTIVE: Among the various psychiatric disorders, depression is a common comorbid condition in cancer patients. Due to the distinct and diverse nature of cancer, the prevalence of depression may be assumed to be affected by differences in primary cancer sites. In this study, we explored the prevalence rates of depression among the ten most prevalent cancers in South Korea using a national patient sample. METHODS: This was a 1-year cross-sectional study using a national patient sample provided by the South Korean National Health Insurance in 2011...
September 2017: Psychiatry Investigation
https://www.readbyqxmd.com/read/29025352/risk-of-colorectal-polyps-and-of-malignancies-in-asymptomatic-carriers-of-mutations-in-the-main-dna-mismatch-repair-genes
#15
Maurizio Ponz de Leon, Monica Pedroni, Annalisa Pezzi, Blerta Sulce, Luca Roncucci, Federica Domati, Giuseppina Rossi, Luca Reggiani Bonetti
OBJECTIVE: Mutation carriers (Mut+) in DNA mismatch repair genes are predisposed to cancer of various organs and to adenomatous polyps; however, they may remain asymptomatic and cancer or polyp-free for several years. We purposed to analyse the clinical follow-up of individuals carrying constitutional mutations in the MLH1, MSH2 or MSH6 genes who were unaffected by benign polyps or malignant tumours at diagnosis. MATERIAL AND METHODS: Mut + subjects (n.81) were members of Lynch syndromes in whom mutations were detected between 1993 and 2015; all were asymptomatic at diagnosis...
October 12, 2017: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/29019325/ambiguity-of-whole-body-pet-ct-scans-in-diagnosis-of-co-existing-tuberculosis-and-malignancy-is-histopathological-confirmation-mandatory
#16
Prekshi Chaudhary, Sweety Gupta, Nitin Leekha, Ravi S Rajendra, Shiv S Mishra, Vandana Arora, Sudarsan De, Sandeep Agarwal
INTRODUCTION: Whole body PET CT is an important investigation tool in malignancy patients and helps in ascertaining the metabolic activity and exact stage of the disease. However, like any other investigation, false positive results do exist and certain diseases other than cancer may show increased uptake. Hence, a careful evaluation of PET CT and clinical correlation in malignancy patients is a must to accomplish the suitable treatment. METHODS: In this retrospective observational study, seven cases of cancer with concomitant tuberculosis were included...
September 2017: Gulf Journal of Oncology
https://www.readbyqxmd.com/read/28983158/correlation-of-two-colposcopic-indices-for-predicting-premalignant-lesions-of-cervix
#17
Sweta Kushwah, Beenu Kushwah
Cervical cancer is the second most common malignancy among women in India, mainly affecting the females of Peri-Menopausal age group. Colposcopy has been very useful for diagnosing cervical cancer to guide the biopsy. Reids and Scalzi proposed the Reids Colposcopic Index (RCI) to make colposcopic diagnosis less subjective, which is currently the most accepted scoring system. Recognizing the correlation of size of the lesion with likelihood of harbouring high grade disease, a new scoring system, the Swede score, has been devised by Strander et al in 2005...
July 2017: Journal of Mid-life Health
https://www.readbyqxmd.com/read/28940341/the-case-for-resource-sensitivity-why-it-is-ethical-to-provide-cheaper-less-effective-treatments-in-global-health
#18
Govind C Persad, Ezekiel J Emanuel
When Dr. Hortense screens her patients in Chicago for cervical dysplasia and cancer, she conducts a pelvic exam, takes a sample of cervical cells, and sends them for Pap cytology and human papilloma virus DNA co-testing. But when she conducts cervical cancer screening in Botswana, she employs a much simpler diagnostic strategy. She applies acetic acid to highlight precancerous lesions and visually inspects the cervix-a technique known as the VIA (visual inspection with acetic acid) method. She treats suspicious lesions with cryotherapy...
September 2017: Hastings Center Report
https://www.readbyqxmd.com/read/28921401/experience-with-curative-radiotherapy-for-cervix-cancer-in-the-bahamas-for-2006-2016
#19
Glenn Jones, Osama Kellini, Nevein Girgis, Darron Halliday, Raleigh Butler, Thomas McGowan, Conville Brown
BACKGROUND: Cervix cancer is a significant health problem. As access to quality care in Small Island Developing States improves, and cancer centers become established, providers of care can summarize local experience to benchmark system quality and look for ways to further improve value. METHODS: This is a retrospective study of all cases of cervix cancer managed 2006-2016 at The Cancer Centre Bahamas, in conjunction with Princess Margaret Hospital, Nassau, affiliated with The University of West Indies...
November 2017: Cancer Causes & Control: CCC
https://www.readbyqxmd.com/read/28900466/can-an-inadequate-cervical-cytology-sample-in-thinprep-be-converted-to-a-satisfactory-sample-by-processing-it-with-a-surepath-preparation
#20
Sveinung Wergeland Sørbye, Mette Kristin Pedersen, Bente Ekeberg, Merete E Johansen Williams, Torill Sauer, Ying Chen
BACKGROUND: The Norwegian Cervical Cancer Screening Program recommends screening every 3 years for women between 25 and 69 years of age. There is a large difference in the percentage of unsatisfactory samples between laboratories that use different brands of liquid-based cytology. We wished to examine if inadequate ThinPrep samples could be satisfactory by processing them with the SurePath protocol. MATERIALS AND METHODS: A total of 187 inadequate ThinPrep specimens from the Department of Clinical Pathology at University Hospital of North Norway were sent to Akershus University Hospital for conversion to SurePath medium...
2017: CytoJournal
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