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https://www.readbyqxmd.com/read/28109718/lipid-core-burden-response-to-stent-implantation-assessed-with-near-infrared-spectroscopy-and-intravascular-ultrasound-evaluation-in-patients-with-myocardial-infarction
#1
Manijeh Noori, Per Thayssen, Karsten Tange Veien, Anders Junker, Knud Nørregaard Hansen, Henrik Steen Hansen, Lisette Okkels Jensen
INTRODUCTION: Near-infrared spectroscopy (NIRS) is a new method to identify lipid core plaque (LCP). The LCP and vascular response were assessed with NIRS to examine whether LCP was compressed or redistributed during percutaneous coronary intervention with stent implantation. METHODS: In 25 patients with non-ST segment elevation myocardial infarction (NSTEMI) NIRS acquisition was performed after predilation, stent implantation with nominal pressure and high-pressure post-dilation with a non-compliant balloon...
December 27, 2016: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/28107355/assessment-of-inter-expert-variability-and-of-an-automated-segmentation-method-of-40-and-60-mhz-ivus-images-of-coronary-arteries
#2
François Destrempes, Marie-Hélène Roy Cardinal, Yoshifumi Saijo, Gérard Finet, Jean-Claude Tardif, Guy Cloutier
The objectives were to compare the performance of a segmentation algorithm, based on the minimization of an uncertainty function, to delineate contours of external elastic membrane and lumen of human coronary arteries imaged with 40 and 60 MHz IVUS, and to use values of this function to delineate portions of contours with highest uncertainty. For 8 patients, 40 and 60 MHz IVUS coronary data acquired pre- and post-interventions were used, for a total of 68,516 images. Manual segmentations of contours (on 2312 images) performed by experts at three core laboratories were the gold-standards...
2017: PloS One
https://www.readbyqxmd.com/read/28105996/coronary-artery-pseudoaneurysm-formed-after-stuck-rotablator-ivus-and-mdct-findings
#3
Umihiko Kaneko, Yoshifumi Kashima, Daitaro Kanno, Tsutomu Fujita
No abstract text is available yet for this article.
January 20, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28104208/first-in-human-evaluation-of-a-novel%C3%A2-polymer-free-drug-filled-stent-angiographic-ivus-oct-and-clinical-outcomes-from%C3%A2-the%C3%A2-revelution-study
#4
Stephen G Worthley, Alexandre Abizaid, Ajay J Kirtane, Daniel I Simon, Stephan Windecker, Sandeep Brar, Ian T Meredith, Sharad Shetty, Ajay Sinhal, Alexandra Popma Almonacid, Daniel Chamié, Akiko Maehara, Gregg W Stone
OBJECTIVES: This study sought to assess the safety and effectiveness of the drug-filled stent (DFS) (Medtronic, Santa Rosa, California) in the treatment of patients with coronary artery disease. BACKGROUND: Polymer-free drug-eluting stents have the potential to improve clinical outcomes and facilitate shorter durations of dual antiplatelet therapy. The polymer-free DFS is made from a trilayered continuous wire with an outer cobalt chromium layer, a middle tantalum layer, and an inner lumen coated with sirolimus...
January 23, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28104120/percutaneous-coronary-intervention-and-coronary-artery-bypass-grafting-in-heart-transplant-recipients-with-transplant-coronary-arterial-vasculopathy
#5
K Kuroda, H Sunami, Y Matsumoto, S Nakajima, T Sato, O Seguchi, H Hata, M Yanase, T Fujita, J Kobayashi, N Fukushima
BACKGROUND: Transplant coronary arterial vasculopathy (TCAV) is a major cause of death after heart transplantation (HTx). Palliative coronary revascularization has been attempted in patients with severe TCAV; however, the outcome has not been fully elucidated. METHODS: Ninety-six patients who were treated after HTx at our institute between 1999 and 2015 were screened for TCAV. TCAV was defined as >70% stenosis on coronary angiography (CAG) or a maximal intimal thickness of >0...
January 2017: Transplantation Proceedings
https://www.readbyqxmd.com/read/28102777/comparison-of-early-vascular-morphological-changes-between-bioresorbable-poly-l-lactic-acid-scaffolds-and-metallic-stents-in-porcine-iliac-arteries
#6
Yasuhito Sekimoto, Hideaki Obara, Kentaro Matsubara, Naoki Fujimura, Hirohisa Harada, Yuko Kitagawa
Bioresorbable scaffolds have the potential to overcome several problems associated with metallic stents. Bioresorbable poly-L-lactic acid (PLLA) scaffold implantation for the treatment of peripheral artery disease has already been reported in animal models and clinical trials; however, no studies comparing PLLA scaffolds and bare metal stents (BMSs) with regard to early vascular morphological changes, identified using intravascular ultrasound (IVUS) analysis, have been reported. In this study, PLLA scaffolds and BMSs were implanted bilaterally in iliac arteries of five miniature pigs...
January 19, 2017: Organogenesis
https://www.readbyqxmd.com/read/28102453/intravascular-ultrasound-versus-digital-subtraction-angiography-direct-comparison-of-intraluminal-diameter-measurements-in-pediatric-and-adolescent-imaging
#7
Anne E Gill, Tadi Ciszak, Hayley Braun, C Matthew Hawkins
BACKGROUND: Intravascular ultrasound (IVUS) allows intraluminal imaging of blood vessels rather than the one-dimensional luminal outline depicted by digital subtraction angiography (DSA). Despite extensive literature in multiple adult vascular diseases, IVUS has not been directly compared to DSA in pediatric and adolescent vascular pathologies. OBJECTIVE: The purpose of this manuscript is to compare absolute luminal diameter measurements obtained via IVUS and DSA during a variety of pediatric endovascular procedures...
January 19, 2017: Pediatric Radiology
https://www.readbyqxmd.com/read/28099219/a-review-of-the-clinical-utility-of-intravascular-ultrasound-ivus-and-optical-coherence-tomography-oct-in-the-assessment-and-treatment-of-coronary-artery-disease
#8
Stephen Daniel Matthews, William H Frishman
Coronary artery disease (CAD) remains one of the leading causes of morbidity and mortality in the United States. As a medical society, we continue to search for ways to better treat CAD and prevent acute coronary syndrome (ACS). As it stands, only statins and anti-platelets agents have been proven to significantly reduce the occurrence of ACS. A histopathological understanding of the pathogenesis of ACS has provided insight into the importance of plaque morphology. Therefore, it has been proposed that increasing the ability to detect true vulnerable, "at-risk" lesions, would foster the use of percutaneous coronary intervention as a means for the prevention of ACS...
January 11, 2017: Cardiology in Review
https://www.readbyqxmd.com/read/28097523/intravascular-ultrasound-characterization-of-a-tissue-engineered-vascular-graft-in-an-ovine-model
#9
Victoria K Pepper, Elizabeth S Clark, Cameron A Best, Ekene A Onwuka, Tadahisa Sugiura, Eric D Heuer, Lilamarie E Moko, Shinka Miyamoto, Hideki Miyachi, Darren P Berman, Sharon L Cheatham, Joanne L Chisolm, Toshiharu Shinoka, Christopher K Breuer, John P Cheatham
Patients who undergo implantation of a tissue-engineered vascular graft (TEVG) for congenital cardiac anomalies are monitored with echocardiography, followed by magnetic resonance imaging or angiography when indicated. While these methods provide data regarding the lumen, minimal information regarding neotissue formation is obtained. Intravascular ultrasound (IVUS) has previously been used in a variety of conditions to evaluate the vessel wall. The purpose of this study was to evaluate the utility of IVUS for evaluation of TEVGs in our ovine model...
January 17, 2017: Journal of Cardiovascular Translational Research
https://www.readbyqxmd.com/read/28092507/real-time-intravascular-ultrasound-and-photoacoustic-imaging
#10
Donald VanderLaan, Andrei B Karpiouk, Doug Yeager, Stanislav Emelianov
Combined intravascular ultrasound and intravascular photoacoustic (IVUS/IVPA) imaging is an emerging hybrid modality being explored as a means of improving the characterization of atherosclerotic plaque anatomical and compositional features. While initial demonstrations of the technique have been encouraging, they have been limited by catheter rotation and data acquisition, displaying, and processing rates on the order of several seconds per frame as well as the use of off-line image processing. Herein, we present a complete IVUS/IVPA imaging system and method capable of real-time IVUS/IVPA imaging, with online data acquisition, image processing, and display of both IVUS and IVPA images...
January 2017: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/28077820/acute-coronary-syndrome-demonstrating-plaque-rupture-in-calcified-lesions-visualized-by-optical-frequency-domain-imaging
#11
Yutaka Goryo, Teruyoshi Kume, Yusuke Kobayashi, Hiroshi Okamoto, Ai Kawamura, Kenzo Fukuhara, Terumasa Koyama, Ryotaro Yamada, Koichiro Imai, Yoji Neishi, Shiro Uemura
A 68-year-old female with acute coronary syndrome was transferred to our hospital. Emergency coronary angiography showed 90% stenosis with severe calcification in the proximal right coronary artery (RCA). Intravascular ultrasound (IVUS) images were obtained and showed circumferential heavy calcification without any evidence of plaque rupture. Optical frequency domain imaging (OFDI) images were obtained in the RCA lesion 3 days after the initial coronary angiography. A cavity of plaque rupture in the calcified plaque by using OFDI was observed in the lesion, which could not be recognized by IVUS...
January 11, 2017: International Heart Journal
https://www.readbyqxmd.com/read/28064551/fd-oct-and-ivus-intravascular-imaging-modalities-in-peripheral-vasculature
#12
S Spiliopoulos, P Kitrou, K Katsanos, D Karnabatidis
Intra-Vascular Ultra-Sound (IVUS) and Frequency Domain-Optical Coherence Tomography (FD-OCT), in vivo, intra-vascular, imaging modalities, widely used in the field of coronary disease, have been recently implemented in peripheral endovascular procedures, for procedural assessment, plaque characterization and determination of predictors of treatment outcomes. Their unique characteristics have also been used in order to provide additional features and improve the performance of re-entry devices and atherotomes...
January 13, 2017: Expert Review of Medical Devices
https://www.readbyqxmd.com/read/28062170/an-artificial-neural-network-method-for-lumen-and-media-adventitia-border-detection-in-ivus
#13
Shengran Su, Zhenghui Hu, Qiang Lin, William Kongto Hau, Zhifan Gao, Heye Zhang
Intravascular ultrasound (IVUS) has been well recognized as one powerful imaging technique to evaluate the stenosis inside the coronary arteries. The detection of lumen border and media-adventitia (MA) border in IVUS images is the key procedure to determine the plaque burden inside the coronary arteries, but this detection could be burdensome to the doctor because of large volume of the IVUS images. In this paper, we use the artificial neural network (ANN) method as the feature learning algorithm for the detection of the lumen and MA borders in IVUS images...
November 17, 2016: Computerized Medical Imaging and Graphics: the Official Journal of the Computerized Medical Imaging Society
https://www.readbyqxmd.com/read/28031233/quantitative-intravascular-biological-fluorescence-ultrasound-imaging-of-coronary-and-peripheral-arteries-in-vivo
#14
Dmitry Bozhko, Eric A Osborn, Amir Rosenthal, Johan W Verjans, Tetsuya Hara, Stephan Kellnberger, Georg Wissmeyer, Saak V Ovsepian, Jason R McCarthy, Adam Mauskapf, Ashley F Stein, Farouc A Jaffer, Vasilis Ntziachristos
AIMS: (i) to evaluate a novel hybrid near-infrared fluorescence-intravascular ultrasound (NIRF-IVUS) system in coronary and peripheral swine arteries in vivo; (ii) to assess simultaneous quantitative biological and morphological aspects of arterial disease. METHODS AND RESULTS: Two 9F/15MHz peripheral and 4.5F/40MHz coronary near-infrared fluorescence (NIRF)-IVUS catheters were engineered to enable accurate co-registrtation of biological and morphological readings simultaneously in vivo...
December 27, 2016: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/28017925/intravascular-ultrasound-and-near-infrared-spectroscopic-features-of-coronary-lesions-with-intraplaque-haemorrhage
#15
Mitsuaki Matsumura, Gary S Mintz, Soo-Jin Kang, Stephen T Sum, Sean P Madden, Allen P Burke, James Goldstein, Rupa Parvataneni, Gregg W Stone, James E Muller, Renu Virmani, Akiko Maehara
AIMS: Intraplaque haemorrhage is considered a major contributor to lesion progression. We assessed coronary lesions with intraplaque haemorrhage using intravascular ultrasound (IVUS) and near-infrared spectroscopy (NIRS). METHODS AND RESULTS: We evaluated coronary arteries from autopsy hearts using 40MHz IVUS and NIRS and compared the imaging findings to histopathology. A total of 2324 2-mm long histological segments from 101 coronary arteries from 56 autopsy hearts were included...
December 25, 2016: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/28012050/comparative-assessment-of-plaque-media-change-on-three-modalities-of-ivus-immediately-after-implantation-of-either-everolimus-eluting-bioresorbable-vascular-scaffold-or-everolimus-eluting-metallic-stent-in-absorb-ii-study
#16
Yaping Zeng, Rafael Cavalcante, Erhan Tenekecioglu, Pannipa Suwannasom, Yohei Sotomi, Carlos Collet, Mahammad Abdelghani, Hans Jonker, Franck Digne, Dieter Horstkotte, Manfred Zehender, Ciro Indolfi, Francesco Saia, Rosario Fiorilli, Bernard Chevalier, Leonardo Bolognese, Javier Goicolea, Shaoping Nie, Yoshinobu Onuma, Patrick W Serruys
The purpose of the study to assess the comparability of immediate changes in plaque/media volume (PV) on three modalities of intravascular ultrasound (IVUS) after implantation of either bioresorbable vascular scaffold (BVS) or everolimus-eluting metallic stent (EES) in Absorb II Study. The two devices have different device volume and ultrasound backscattering that may interfere with the "plaque/media" assessed by three modalities on IVUS: grayscale, backscattering of radiofrequency and brightness function. In a multicenter randomized controlled trial, 501 patients with stable or unstable angina underwent documentary IVUS pre- and post- implantation...
December 23, 2016: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/28010920/computer-aided-diagnosis-of-coronary-artery-disease-myocardial-infarction-and-carotid-atherosclerosis-using-ultrasound-images-a-review
#17
REVIEW
Oliver Faust, U Rajendra Acharya, Vidya K Sudarshan, Ru San Tan, Chai Hong Yeong, Filippo Molinari, Kwan Hoong Ng
The diagnosis of Coronary Artery Disease (CAD), Myocardial Infarction (MI) and carotid atherosclerosis is of paramount importance, as these cardiovascular diseases may cause medical complications and large number of death. Ultrasound (US) is a widely used imaging modality, as it captures moving images and image features correlate well with results obtained from other imaging methods. Furthermore, US does not use ionizing radiation and it is economical when compared to other imaging modalities. However, reading US images takes time and the relationship between image and tissue composition is complex...
December 20, 2016: Physica Medica: PM
https://www.readbyqxmd.com/read/27999810/development-of-a-new-hybrid-biodegradable-drug-eluting-stent-for-the-treatment-of-peripheral-artery-disease
#18
Jung-Hee Lee, Soon-Joong Kim, Se-Il Park, Young-Guk Ko, Donghoon Choi, Myeong-Ki Hong, Yangsoo Jang
This study aimed to develop a new biodegradable stent for peripheral artery disease (PAD) that could provide sufficient radial force to maintain long-term patency and flexibility. All self-expandable hybrid biodegradable stents were designed by using a knitting structure composed of poly-L-lactic acid (PLLA) and nitinol. Four different types of stents were implanted in 20 iliac arteries in 10 mini pigs as follows: a bare-metal stent (BMS) (group 1, n = 5), a drug-free hybrid stent (group 2, n = 5), a 50% (50 : 100, w/w) paclitaxel (PTX)/poly-lactide-co-glycolic acid (PLGA; fast PTX-releasing form) hybrid stent (group 3, n = 5), and a 30% (30 : 100, w/w) PTX/PLGA (slow PTX-releasing form) hybrid stent (group 4, n = 5)...
2016: BioMed Research International
https://www.readbyqxmd.com/read/27998841/automated-characterisation-of-lipid-core-plaques-in-vivo-by-quantitative-optical-coherence-tomography-tissue-type-imaging
#19
Muthukaruppan Gnanadesigan, Takeyoshi Kameyama, Antonios Karanasos, Nienke S van Ditzhuijzen, Johannes N van der Sijde, Robert-Jan van Geuns, Jurgen Ligthart, Karen Witberg, Giovanni J Ughi, Antonius F van der Steen, Evelyn Regar, Gijs van Soest
AIMS: Qualitative criteria for plaque tissue characterisation by OCT are well established, but quantitative methods lack systematic validation in vivo. High optical attenuation coefficient µt has been associated with unstable plaque features, such as lipid core. The purpose of this study was to validate optical coherence tomography (OCT) attenuation imaging for tissue characterisation in vivo, specifically to detect lipid core in coronary atherosclerotic plaques, and to evaluate quantitatively the ability of OCT attenuation imaging to differentiate thin-cap (TCFA) and thick-cap fibroatheroma (FA)...
December 20, 2016: EuroIntervention
https://www.readbyqxmd.com/read/27998840/quantification-and-characterisation-of-released-plaque-material-during-bioresorbable-vascular-scaffold-implantation-into-right-coronary-artery-lesions-by-multimodality-intracoronary-imaging
#20
Heike A Hildebrandt, Polykarpos C Patsalis, Fadi Al-Rashid, Markus Neuhäuser, Tienush Rassaf, Gerd Heusch, Philipp Kahlert, Petra Kleinbongard
AIMS: We aimed to compare intravascular ultrasound with virtual histology (VH-IVUS), optical coherence tomography (OCT) and near-infrared spectroscopy (NIRS) for their ability to quantify the true amount and characterise the nature of released plaque material during bioresorbable vascular scaffold (BVS) implantation into right coronary artery (RCA) lesions using a distal occlusion and aspiration device. METHODS AND RESULTS: Seventeen patients underwent BVS implantation into the right coronary artery under distal protection with intracoronary imaging using VH-IVUS, OCT and NIRS...
December 20, 2016: EuroIntervention
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