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https://www.readbyqxmd.com/read/28938379/dark-endothelial-spots-after-descemet-membrane-endothelial-keratoplasty-may-appear-as-recurrent-fuchs-dystrophy-or-herald-graft-failure-or-rejection
#1
Vasiliki Zygoura, Lamis Baydoun, Claire Monnereau, Maria Satué, Silke Oellerich, Gerrit R J Melles
PURPOSE: To evaluate the clinical significance of dark spots in the donor endothelial cell layer as observed with specular microscopy, in patients who underwent Descemet membrane endothelial keratoplasty (DMEK) for Fuchs endothelial dystrophy (FED). METHODS: Specular microscopy images of 83 consecutive eyes up to 7 years after DMEK were retrospectively reviewed in a masked fashion for the presence of dark spots and morphologic changes in the endothelial cell layer and processed for endothelial cell density (ECD) measurements...
September 21, 2017: Cornea
https://www.readbyqxmd.com/read/28938305/a-useful-device-to-measure-kinetics-of-platelet-contraction
#2
Mitchell J George, Kevin R Aroom, Max A Skibber, Tushar Sharma, Charles E Wade, Charles S Cox, Brijesh S Gill
Platelet contraction provides a minimally invasive source for physiologic information. In this article, we describe a device that directly measures the kinetics of platelet contraction. Whole blood is injected between acrylic plates and an adherent clot forms. The bottom plate is fixed, and the top plate is attached to a wire cantilever. Platelet contraction drives deflection of the wire cantilever which is captured by a camera. Force generated by the clot with time is derived using beam equations. Force derivations were verified using a microelectromechanical (MEMS) force sensor...
September 21, 2017: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/28938202/effect-of-different-diode-laser-wavelengths-on-root-dentin-decontamination-infected-with-enterococcus-faecalis
#3
Caroline Cristina Borges, Carlos Estrela, Fabiane Carneiro Lopes, Regina Guenka Palma-Dibb, Jesus Djalma Pecora, Cyntia Rodrigues De Araújo Estrela, Manoel Damião de Sousa-Neto
The objective of this study was to evaluate the antibacterial effect and the ultrastructural alterations of diode laser with different wavelengths (808nm and 970nm) and its association with irrigating solutions (2.5% sodium hypochlorite and 2% chlorhexidine) in root dentin contaminated by a five days biofilm. Thirteen uniradicular teeth were sectioned into 100 dentin intraradicular blocks. Initially, the blocks were immersed for 5min in 17% EDTA and washed with distilled water for 5min, then samples were sterilized for 30min at 120°C...
September 13, 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/28938147/development-of-an-experimental-model-of-burst-fracture-with-damage-characterization-of-the-vertebral-bodies-under-dynamic-conditions
#4
A Germaneau, T Vendeuvre, M Saget, P Doumalin, J C Dupré, F Brémand, F Hesser, C Brèque, P Maxy, M Roulaud, O Monlezun, P Rigoard
BACKGROUND: Burst fractures represent a significant proportion of fractures of the thoracolumbar junction. The recent advent of minimally invasive techniques has revolutionized the surgical treatment of this type of fracture. However mechanical behaviour and primary stability offered by these solutions have to be proved from experimental validation tests on cadaveric specimens. Therefore, the aim of this study was to develop an original and reproducible model of burst fracture under dynamic impact...
September 13, 2017: Clinical Biomechanics
https://www.readbyqxmd.com/read/28938145/six-scalemic-mixtures-of-6-monosubstituted-dihydrobenzophenanthridine-alkaloids-from-chelidonium-majus-and-optically-active-structures-of-enantiomers
#5
An-Jun Deng, Hai-Jing Zhang, Qian Li, Zhi-Hong Li, Zhi-Hui Zhang, Lian-Qiu Wu, Li Li, Hai-Lin Qin
Six pairs of previously undescribed 6-monosubstituted dihydrobenzophenanthridine alkaloids were separated as corresponding six scalemic mixtures from the aerial part of Chelidonium majus. The elucidation for the 2D structures of these alkaloids was achieved using regular spectroscopic and chemical methods. The assignment of scalemic-mixture nature was achieved using combined examinations of their NMR data, CD spectra, calculation of specific rotations, and chiral HPLC profiles. The identification for the relative configurations of alkaloids possessing two asymmetric carbons directly connected up by a rotatable sp(3)-sp(3) carbon-carbon single bond was significantly facilitated by discussing the erythro and threo relative configurations defined by the mutuality of the orders of decreasing steric hindrances between the two sets of ligands linked to the two chiral centers...
September 19, 2017: Phytochemistry
https://www.readbyqxmd.com/read/28938068/direct-patterning-of-zinc-sulfide-on-a-sub-10-nanometer-scale-via-electron-beam-lithography
#6
Mohammad S M Saifullah, Mohamed Asbahi, Maryam Binti-Kamran Kiyani, Sudhiranjan Tripathy, Esther A H Ong, Asadullah Ibn Saifullah, Hui Ru Tan, Tanmay Dutta, Ramakrishnan Ganesan, Suresh Valiyaveettil, Karen Siew-Ling Chong
Nanostructures of metal sulfides are conventionally prepared via chemical techniques and patterned using self-assembly. This poses a considerable amount of challenge when arbitrary shapes and sizes of nanostructures are desired to be placed at precise locations. Here we describe an alternative approach of nanoscale patterning of zinc sulfide (ZnS) directly using a spin-coatable and electron beam-sensitive zinc butylxanthate resist without the lift-off or etching step. Time-resolved electron beam damage studies using micro-Raman and micro-FTIR spectroscopies suggest that exposure to a beam of electrons lead to quick disappearance of xanthate moieties most likely via the Chugaev elimination, and further increase of electron dose results in the appearance of ZnS, thereby making the exposed resist insoluble in organic solvents...
September 22, 2017: ACS Nano
https://www.readbyqxmd.com/read/28938067/a-single-chain-photoswitchable-crispr-cas9-architecture-for-light-inducible-gene-editing-and-transcription
#7
Xin X Zhou, Xinzhi Zou, Hokyung K Chung, Yuchen Gao, Yanxia Liu, Lei S Qi, Michael Z Lin
Optical control of CRISPR-Cas9-derived proteins would be useful for restricting gene editing or transcriptional regulation to desired times and places. Optical control of Cas9 functions has been achieved with photouncageable unnatural amino acids or by using light-induced protein interactions to reconstitute Cas9-mediated functions from two polypeptides. However, these methods have only been applied to one Cas9 species and have not been used for optical control of different perturbations at two genes. Here, we use photodissociable dimeric fluorescent protein domains to engineer single-chain photoswitchable Cas9 (ps-Cas9) proteins in which the DNA-binding cleft is occluded at baseline and opened upon illumination...
September 22, 2017: ACS Chemical Biology
https://www.readbyqxmd.com/read/28938019/fabrication-of-3-methoxyphenol-sensor-based-on-fe3o4-decorated-carbon-nanotube-nanocomposites-for-environmental-safety-real-sample-analyses
#8
Mohammed M Rahman, Mohammad Musarraf Hussain, Abdullah M Asiri
Iron oxide ornamented carbon nanotube nanocomposites (Fe3O4.CNT NCs) were prepared by a wet-chemical process in basic means. The optical, morphological, and structural characterizations of Fe3O4.CNT NCs were performed using FTIR, UV/Vis., FESEM, TEM; XEDS, XPS, and XRD respectively. Flat GCE had been fabricated with a thin-layer of NCs using a coating binding agent. It was performed for the chemical sensor development by a dependable I-V technique. Among all interfering analytes, 3-methoxyphenol (3-MP) was selective towards the fabricated sensor...
2017: PloS One
https://www.readbyqxmd.com/read/28937970/spectroscopy-and-enhanced-frequency-upconversion-in-nd-3-yb-3-codoped-tpo-glasses-energy-transfer-and-nir-to-visible-upconverter
#9
Mohd Azam, Vineet Kumar Rai, Deepak Kumar Mohanty
TeO2-Pb3O4 (TPO) glasses codoped with Nd(3+) and Yb(3+) ions have been fabricated by conventional melting technique. The absorption, emission and excitation spectra of the samples have been recorded. The optical band gap in both the doped/codoped glasses is found to be ∼3.31 eV. Judd-Ofelt analysis has been carried out by using the absorption spectrum of 0.8 mol% Nd(3+) doped glass to determine the radiative properties viz radiative transition probabilities, branching ratios, radiative lifetimes, quality factor and emission cross sections of some emitting levels for Nd(3+) ions...
September 22, 2017: Methods and Applications in Fluorescence
https://www.readbyqxmd.com/read/28937877/changes-in-peripapillary-nerve-fiber-layer-thickness-after-adjuvant-stereotactic-radiotherapy-in-patients-with-neovascular-age-related-macular-degeneration
#10
Mahdy Ranjbar, Maximilian Kurz, Annekatrin Holzhey, Dirk Rades, Salvatore Grisanti
PURPOSE: To evaluate the effect of stereotactic radiotherapy (SRT) in conjunction with intravitreal injections (IVI) of anti-vascular endothelial growth factor (anti-VEGF) drugs on peripapillary retinal nerve fiber layer (pRNFL) thickness in patients with neovascular age-related macular degeneration (nAMD). METHODS: This was a retrospective, observational case series of patients with nAMD, who underwent SRT and subsequently had at least 12 months of complete follow-up...
September 22, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28937876/pilot-study-of-the-pulsatile-neuro-peripapillary-retinal-deformation-in-glaucoma-and-its-relationship-with-glaucoma-risk-factors
#11
Maribel Hidalgo-Aguirre, Santiago Costantino, Mark Richard Lesk
PURPOSE: To perform a pilot study of the neuro-peripapillary retinal tissue deformation during the cardiac cycle among healthy eyes, ocular hypertensive (OHT), open angle glaucoma suspect (OAG-S), and early open angle glaucoma (EOAG) patients using video rate optical coherence tomography (OCT) image series. METHODS: OCT line scan sequences of the same region of the optic nerve head (ONH) were obtained from 15 EOAG, 6 OHT, 10 OAG-S, and 10 healthy age-matched eyes...
September 22, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28937859/choroidal-thickness-in-traumatic-optic-neuropathy
#12
Ju-Yeun Lee, Doo-Ri Eo, Kyung-Ah Park, Sei Yeul Oh
PURPOSE: To examine the choroidal thickness in patients with indirect traumatic optic neuropathy (TON) Methods: Patients with unilateral traumatic optic neuropathy over a period of 4 years were included in this study. Horizontal and vertical enhanced-depth imaging (EDI) from spectral-domain optical coherence tomography (SD-OCT) scans of the fovea were obtained in patients with unilateral TON within 2 weeks of injury. The main outcome measure was the choroidal thickness at nine locations...
September 22, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28937857/evaluation-of-retinal-blood-flow-before-and-after-panretinal-photocoagulation-using-pattern-scan-laser-for-diabetic-retinopathy
#13
Yoshihisa Yamada, Kiyoshi Suzuma, Naoko Onizuka, Masafumi Uematsu, Yasser Helmy Mohamed, Takashi Kitaoka
PURPOSE: Laser speckle flowgraphy (LSFG) can measure blood flow in the ocular fundus. We analyzed the relationship between retinal blood flow and panretinal photocoagulation (PRP) in diabetic retinopathy. METHODS: This retrospective observational study examined the eyes of 35 patients with proliferative diabetic retinopathy (PDR) or non-PDR (NPDR). PRP was performed using a pattern scan laser. Using LSFG, blood flow was evaluated as the mean blur rate (MBR) or the relative flow volume (RFV)...
September 22, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28937833/oct-angiography-for-monitoring-and-managing-neovascular-age-related-macular-degeneration
#14
P Malamos, G Tsolkas, M Kanakis, G Mylonas, D Karatzenis, N Oikonomopoulos, J Lakoumentas, Ilias Georgalas
PURPOSE: To evaluate the combined use of optical coherence tomography and angiography (OCT-A) for imaging choroidal neovascularization (CNV) secondary to neovascular age-related macular degeneration (nAMD). MATERIALS AND METHODS: This prospective observational study was conducted from May 2015 to April 2017. Included in the study were 54 patients (n = 63 eyes), all of whom had CNV secondary to nAMD and all of whom had been examined by OCT-A. Angioscans (3x3 and 6 × 6) and conventional B-scan OCT scans were obtained for all patients at baseline and at various times during the 24-month follow-up period...
September 22, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28937828/the-effects-of-systemic-alfuzosin-and-tamsulosin-hydrochloride-on-choroidal-thickness-and-pupil-diameter-sizes-in-cases-with-benign-prostatic-hyperplasia
#15
Mustafa Dogan, Bunyamin Kutluksaman, Ibrahim Keles, Mustafa Karalar, Ahmet Omer Halat
PURPOSE: To compare the effects of alfuzosin hydrochloride and tamsulosin hydrochloride on choroidal thickness (CT) and pupil diameter (PD) sizes in patients with benign prostatic hyperplasia. SUBJECTS AND METHODS: Sixty-three men patients with newly diagnosis of benign prostatic hyperplasia were randomly assigned to either alfuzosin hydrochloride or to tamsulosin hydrochloride groups in this prospective, randomized, parallel-group clinical trial. Enhanced depth imaging spectral-domain optical coherence tomography, pupillography were obtained at baseline, 1st and 3rd month, and choroidal thicknesses and pupil diameter sizes were compared between the two groups...
September 22, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28937826/choroidal-variations-in-diabetic-macular-edema-fluorescein-angiography-and-optical-coherence-tomography
#16
Xiangning Wang, Shuting Li, Wei Li, Yanjun Hua, Qiang Wu
PURPOSES: To (i) evaluate variations in choroidal thickness (CT) and choroidal volume (CV) in diabetic macular edema (DME), as demonstrated by fluorescein angiography (FA) and enhanced depth-imaging (EDI) optical coherence tomography (OCT) (EDI-OCT) and (ii) correlate these variations with visual acuity. METHODS: This study was a retrospective observational case series of patients with diabetic retinopathy (DR) and DME. The study groups comprised 77 DR patients (n = 87), all of whom underwent color fundus photography, FA, and OCT on the same day...
September 22, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28937823/optic-disc-parameters-of-myopic-children-with-atropine-treatment
#17
Li-Wei Chan, Yi-Ting Hsieh, Wei-Cherng Hsu, Han-Chih Cheng, Elizabeth P Shen
PURPOSE: To characterize optic disc parameters, retinal nerve fiber layer thickness (RNFLT), and the intraocular pressure (IOP) of myopic children under continual topical 0.25% atropine treatment. METHODS: From October 1, 2010 to September 31, 2011, 67 eyes of 35 myopic children were recruited. The children were treated with 0.25% atropine nightly for myopia control. Visual acuity, refraction, IOP, axial length (AL, IOL Master), RNFLT, and optic disc parameters (Stratus OCT) were measured at enrollment and every 2 months...
September 22, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28937772/terahertz-light-matter-interaction-beyond-unity-coupling-strength
#18
Andreas Bayer, Marcel Pozimski, Simon Schambeck, Dieter Schuh, Rupert Huber, Dominique Bougeard, Christoph Lange
Achieving control over light-matter interaction in custom-tailored nanostructures is at the core of modern quantum electrodynamics. In strongly and ultrastrongly coupled systems, the excitation is repeatedly exchanged between a resonator and an electronic transition at a rate known as the vacuum Rabi frequency ΩR. For ΩR approaching the resonance frequency ωc, novel quantum phenomena including squeezed states, Dicke superradiant phase transitions, the collapse of the Purcell effect, and a population of the ground state with virtual photon pairs are predicted...
September 22, 2017: Nano Letters
https://www.readbyqxmd.com/read/28937748/bio-optics-and-bio-inspired-optical-materials
#19
Sirimuvva Tadepalli, Joseph M Slocik, Maneesh K Gupta, Rajesh R Naik, Srikanth Singamaneni
Through the use of the limited materials palette, optimally designed micro- and nanostructures, and tightly regulated processes, nature demonstrates exquisite control of light-matter interactions at various length scales. In fact, control of light-matter interactions is an important element in the evolutionary arms race and has led to highly engineered optical materials and systems. In this review, we present a detailed summary of various optical effects found in nature with a particular emphasis on the materials and optical design aspects responsible for their optical functionality...
September 22, 2017: Chemical Reviews
https://www.readbyqxmd.com/read/28937745/mononuclear-fe-ii-complexes-based-on-the-methylpyrazinyl-diamine-ligand-chemical-thermo-and-photocontrol-of-their-magnetic-switchability
#20
Xue Liu, Jian Zhou, Xin Bao, Zheng Yan, Guo Peng, Mathieu Rouzières, Corine Mathonière, Jun-Liang Liu, Rodolphe Clérac
Two new mononuclear Fe(II) complexes, [Fe((2Me)Lpz)(NCX)2] (L = N,N'-dimethyl-N,N'-bis((pyrazin-2-yl)methyl)-1,2-ethanediamine and X = S (1), BH3 (2)), have been synthesized and characterized by single-crystal X-ray diffraction, magnetic, optical reflectivity, and photomagnetic measurements. They have similar FeN6 coordination environments offered by the tetradentate ligand with a cis-α conformation and two NCX(-) coligands in cis positions. However, 1 and 2 have different molecular arrangements and crystal packings, and are isolated in orthorhombic Pbnb and monoclinic C2/c space groups, respectively...
September 22, 2017: Inorganic Chemistry
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