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anemia in the elderly

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https://www.readbyqxmd.com/read/29213001/-resumption-of-enteral-nutrition-using-enteral-formula-containing-sodium-alginate-following-hemorrhaging-after-endoscopic-sphincterotomy-a-case-report
#1
Tetsuro Akashi, Kazuhide Matsumoto, Risa Hashimoto, Naomi Koikawa, Masaki Yamada, Junko Shimizu, Chisato Kakegawa, Mari Nakamura, Chieko Kumamoto
Enteral nutrition is often performed in elderly patients with dysphagia. Choledocholithiasis is a disease that is common in elderly patients. Gastrointestinal hemorrhaging can occur in association with endoscopic sphincterotomy, and subsequent enteral nutrition must be carefully resumed. We herein report our experience using Mermed Plus containing sodium alginate after endoscopic hemostasis. The patient was an 88-year-old woman with an onset of gallstone cholangitis during rehabilitation after cerebral infarction...
2017: Nihon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics
https://www.readbyqxmd.com/read/29212527/anemia-is-associated-with-incidence-of-dementia-a-national-health-screening-study-in-korea-involving-37-900-persons
#2
Su-Min Jeong, Dong Wook Shin, Ji Eun Lee, Jung Hyeon Hyeon, Jinkook Lee, SangYun Kim
BACKGROUND: The aim of this study was to investigate whether anemia is associated with dementia incidence in the elderly. METHODS: Using the Korean National Health Insurance Service-National Health Screening Cohort (NHIS-HEALS) database, we identified 66-year-old subjects (n = 37,900) who were free of dementia and stroke. Anemia (hemoglobin < 12 g/dl for women and < 13 g/dl for men) and the severity of anemia (mild, moderate, or severe) were defined using World Health Organization criteria...
December 6, 2017: Alzheimer's Research & Therapy
https://www.readbyqxmd.com/read/29211362/clinical-differences-of-helicobacter-pylori-infection-in-children
#3
REVIEW
Barbara M Iwańczak, Anna M Buchner, Franciszek Iwańczak
Helicobacter pylori infection is widely spread all over the world. The prevalence of H. pylori infection in the world varies and depends on numerous factors such as age, ethnicity, geographical and socioeconomic status. Humans have been in a symbiotic relationship with this bacterium for thousands of years. However 10-20% of people infected with H. pylori are likely to develop gastroduodenal diseases such as peptic ulcer disease, iron deficiency anemia, gastric mucosal atrophy, metaplasia, dysplasia, MALT lymphoma, or gastric adenocarcinoma...
October 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/29201323/does-serum-lipid-profile-differ-in-anemia-and-non-anemic-older-subjects
#4
Mahshid Shirvani, Mohsen Vakili Sadeghi, Seyed Reza Hosseini, Ali Bijani, Reza Ghadimi
Background: There is some evidence that shows the symptoms of anemia are fewere in overweight and obese people, so, the purpose of this research was to study the relationship between anemia and iron deficiency anemia (IDA) with lipid profile status of the elderly. Methods: This cross-sectional study came from the Amirkola Health and Ageing Project (AHAP). A demographic questionnaire was given to the older people and a blood sample was obtained to assay their lipid indexes (triglyceride, cholesterol, HDL and LDL) and the parameters related to anemia after 12 hours fasting...
2017: Caspian Journal of Internal Medicine
https://www.readbyqxmd.com/read/29199087/primary-total-knee-arthroplasty-for-acute-fracture-around-the-knee
#5
REVIEW
S Parratte, M Ollivier, J-N Argenson
Relatively poor results have been reported with open reduction and internal fixation of complex fractures around the knee in elderly osteoporotic patients, and primary total knee arthroplasty (TKA) has been proposed as an alternative solution. While limiting the number of procedures, it meets two prerequisites: 1) to save the patient's life, thanks to early weight-bearing, to limit decubitus complications; and 2) to save knee function and patient autonomy, thanks to early knee mobilization. There are 3 main indications: complex articular fractures in elderly patients with symptomatic osteoarthritis prior to fracture; complex articular fractures of the tibial plateau in elderly patients whose bone quality makes internal fixation hazardous; and major destruction of the distal femur in younger patients...
November 30, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/29191594/a-phase-ii-trial-of-carboplatin-plus-s-1-for-elderly-patients-with-advanced-non-small-cell-lung-cancer-with-wild-type-epidermal-growth-factor-receptor-the-okayama-lung-cancer-study-group-trial-1202
#6
Shoichi Kuyama, Nobuaki Ochi, Akihiro Bessho, Katsuyuki Hotta, Genyo Ikeda, Daizo Kishino, Toshio Kubo, Daijiro Harada, Nobukazu Fujimoto, Masamoto Nakanishi, Takahiro Umeno, Toshiaki Okada, Kenichi Chikamori, Tomoko Yamagishi, Kadoaki Ohashi, Eiki Ichihara, Nagio Takigawa, Mitsune Tanimoto, Katsuyuki Kiura
INTRODUCTION: S-1 is an oral fluoropyrimidine-based combination of tegafur, gimeracil, and oteracil potassium. Although the combination of S-1 with carboplatin is a first-line chemotherapy regimen for advanced non-small cell lung cancer (NSCLC), the efficacy and safety of the regimen in the elderly remain unknown. METHODS: The patient inclusion criteria were previously untreated advanced NSCLC, wild-type epidermal growth factor receptor, aged 70 years or more, and a performance status (PS) of 0-2...
October 2017: Lung Cancer: Journal of the International Association for the Study of Lung Cancer
https://www.readbyqxmd.com/read/29184050/a-rare-case-of-bochdalek-hernia-with-concomitant-para-esophageal-hernia-repaired-laparoscopically-in-an-octogenarian
#7
Sergio Susmallian, Asnat Raziel
BACKGROUND A Bochdalek hernia (BH) is a rare congenital condition consisting of a posterolateral defect in the diaphragm. A para-esophageal hernia (PEH) is a rare variant of hiatus hernia. BH and PEH may present with gastric volvulus or incarceration, requiring emergency treatment. Minimally invasive surgery is the preferred treatment, particularly for elderly patients and patients with comorbidities. The occurrence of BH with concomitant PEH is a very rare event. We describe a case of an octogenarian patient with BH and concomitant PEH treated laparoscopically...
November 29, 2017: American Journal of Case Reports
https://www.readbyqxmd.com/read/29182590/study-on-the-prevalence-of-severe-anemia-among-non-pregnant-women-of-reproductive-age-in-rural-china-a-large-population-based-cross-sectional-study
#8
Qiuyue Ma, Shikun Zhang, Jue Liu, Qiaomei Wang, Haiping Shen, Yiping Zhang, Min Liu
Globally, severe anemia impacts millions of non-pregnant women. However, studies on the prevalence of severe anemia through large epidemiologic surveys among non-pregnant women have been scarce in China. In this study, we aimed to study the prevalence of severe anemia and its determinants among non-pregnant women living in rural areas of China. Data were gathered for 712,101 non-pregnant women aged between 21 and 49 years who attended the 2012 National Free Preconception Health Examination Project. Severe anemia in non-pregnant women was defined as a hemoglobin (Hb) concentration lower than 80 g/L...
November 28, 2017: Nutrients
https://www.readbyqxmd.com/read/29176817/individual-and-community-factors-contributing-to-anemia-among-women-in-rural-baja-california-mexico
#9
Molly A Moor, Miguel A Fraga, Richard S Garfein, Hooman H Rashidi, John Alcaraz, Donna Kritz-Silverstein, John P Elder, Stephanie K Brodine
INTRODUCTION: Anemia is a public health concern among women in rural Baja California, Mexico. The purpose of this study was to identify the individual and community factors contributing to the disproportionately high prevalence of anemia among women in this region. METHODS: A cross-sectional study of 118 women (15-49 years) was performed in a rural colonia (small settlement) in Baja California, Mexico in 2012. Participants completed a survey comprised of demographic, socioeconomic, health, and dietary questions and provided a capillary blood sample...
2017: PloS One
https://www.readbyqxmd.com/read/29170252/nationwide-survey-on-the-use-of-eltrombopag-in-patients-with-severe-aplastic-anemia-a-report-on-behalf-of-the-french-reference-center-for-aplastic-anemia
#10
Etienne Lengline, Bernard Drenou, Pierre Peterlin, Olivier Tournilhac, Julie Abraham, Ana Berceanu, Brigitte Dupriez, Gaelle Guillerm, Emmanuel Raffoux, Flore Sicre de Fontbrune, Lionel Ades, Marie Balsat, Driss Chaoui, Paul Coppo, Selim Corm, Thierry Leblanc, Natacha Maillard, Louis Terriou, Gerard Socié, Regis Peffault de la Tour
Few therapeutic options are available for aplastic anemia patients ineligible for transplantation or refractory to immunosuppressive therapy. Eltrombopag recently showed tri-lineage responses in refractory patients. However, real-life use of this drug remains unknown. This retrospective study (2012-2016) was conducted by the French Reference Center for Aplastic anemia on patients with relapse/refractory aplastic anemia, and patients ineligible for anti-thymocyte globulin (naive) or transplantation, who received eltrombopag for at least two months...
November 23, 2017: Haematologica
https://www.readbyqxmd.com/read/29169901/-transfusion-practices-in-elderly-patients-a-descriptive-study-about-241%C3%A2-patients-at-the-university-hospital-of-brest
#11
C Le Niger, N Magne Tagne, A Gentric
Red blood cell transfusion is commonly required for elderly patients with little specific guidelines for this population. We wished to study the transfusion practices for patients aged≥75 years transfused with red blood cells in all units of our institution. The aim of this work is to describe this population of patients and to compare the transfusion practices to the HAS and ANSM guidelines published in 2014. METHODS: An observational study was performed including patients≥75 years, transfused with red blood cells between 27th January to 27th March 2014...
November 20, 2017: Transfusion Clinique et Biologique: Journal de la Société Française de Transfusion Sanguine
https://www.readbyqxmd.com/read/29156802/efficacy-and-safety-of-first-line-pemetrexed-plus-carboplatin-followed-by-single-agent-pemetrexed-maintenance-in-elderly-chinese-patients-with-non-squamous-non-small-cell-lung-cancer
#12
Xinmin Zhao, Hui Yu, Jing Zhao, Xianghua Wu, Si Sun, Zhiguo Luo, Huijie Wang, Jie Qiao, Jianhua Chang, Jialei Wang
Chemotherapy with pemetrexed plus carboplatin followed by pemetrexed maintenance therapy is a first-line regimen for patients with advanced non-squamous non-small-cell lung cancer. This phase II clinical study investigated the efficacy and safety of this regimen in older patients (aged ≥65 years) with advanced non-squamous non-small-cell lung cancer. All patients received 4 courses of induction therapy with pemetrexed (500 mg/m(2)) combined with carboplatin once every 3 weeks. If patients had stable disease or achieved a complete or partial tumor response after 4 courses of pemetrexed + carboplatin therapy, maintenance treatment with pemetrexed monotherapy was administered until either disease progression or intolerable toxicity occurred...
October 17, 2017: Oncotarget
https://www.readbyqxmd.com/read/29153343/prevalence-of-anemia-in-hospitalized-internal-medicine-patients-correlations-with-comorbidities-and-length-of-hospital-stay
#13
Carlo Zaninetti, Catherine Klersy, Concetta Scavariello, Raffaella Bastia, Carlo L Balduini, Rosangela Invernizzi
BACKGROUND: Several studies have documented a linear growth of the prevalence of anemia with aging. Especially in hospitalized elderly patients, anemia can aggravate the course of chronic disorders, and ultimately get worse the clinical outcomes. METHODS: To evaluate the distribution, the main causes, and the possible correlations of anemia with comorbidities and length of hospitalization in a population of internal medicine inpatients, we carried out an observational study on a cohort of 923 consecutive admissions relative to 856 subjects...
November 16, 2017: European Journal of Internal Medicine
https://www.readbyqxmd.com/read/29144542/autoimmune-diseases-and-breast-cancer-risk-by-tumor-hormone-receptor-status-among-elderly-women
#14
Catherine Schairer, Ruth M Pfeiffer, Shahinaz M Gadalla
The female preponderance of many autoimmune diseases suggests a possible hormonal etiology. Little research exists on systemic and organ-specific autoimmune diseases and risk of breast cancer by tumor estrogen receptor (ER)- and progesterone receptor (PR)- status. Here we evaluate associations between selected systemic and organ-specific autoimmune diseases and breast cancer risk overall and by tumor ER- and PR-status. We used linked Surveillance, Epidemiology and End Results (SEER)-Medicare data, with first female breast cancer cases ages ≥66 years identified by SEER registries (years 1992-2011) (N = 209,929)...
November 16, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/29141943/anemia-at-older-age-etiologies-clinical-implications-and-management
#15
Reinhard Stauder, Peter Valent, Igor Theurl
Anemia is quite frequently diagnosed in older individuals and is a key indicator of various reactive and clonal conditions. Many underlying diseases, like the myelodysplastic syndromes (MDS), develop preferentially in elderly individuals. The prevalence of anemia at older age is increasing, and this is mainly due to more frequently applied diagnostics and demographic changes in our societies. The etiology of anemia at older age is complex and ranges from bone marrow failure syndromes to chronic kidney disease, and from nutritional deficiencies to inflammatory processes including inflammaging in immunosenescence...
November 15, 2017: Blood
https://www.readbyqxmd.com/read/29136746/-study-on-handgrip-strength-of-elderly-%C3%A2-60-years-old-from-longevity-areas-in-china
#16
L Q Su, Z X Yin, X C Wang, Y B Lyu, W H Shi, J Zhang, J S Luo, X M Shi
Objective: To assess the status of handgrip strength of elderly population from longevity areas in China, and to analyze the correlative factors of handgrip strength of elderly people. Methods: Data from Chinese Longitudinal Healthy Longevity Survey (CLHLS) in 2012 was used, from which1 967 participants aged ≥60 years old with valid data of grip strength value from 8 Chinese longevity areas were included. Information on demographics characteristic, life style and health status was collected using questionnaires...
November 6, 2017: Zhonghua Yu Fang Yi Xue za Zhi [Chinese Journal of Preventive Medicine]
https://www.readbyqxmd.com/read/29121039/the-prevalence-and-determinants-of-multimorbidity-in-hospitalized-patients-with-heart-failure
#17
Olga Siga, Barbara Wizner, Karolina Piotrowicz, Małgorzata Fedyk-Łukasik, Tomasz Grodzicki
OBJECTIVE: The aim of this study was to assess the prevalence of multimorbidity and co-existed diseases in hospitalized patients with heart failure (HF) in relation to age and gender. METHODS: The nationwide cross-sectional survey had been conducted in Poland (April-November 2013), in 260 randomly selected hospital wards. A trained nurse contacted with one physician, drawn from the list of all doctors working in the selected hospital's wards, who completed the study questionnaires regarding to clinical characteristics of the last five HF patients, who were discharged from an internal or cardiology ward...
2017: Folia Medica Cracoviensia
https://www.readbyqxmd.com/read/29118292/-impact-of-frailty-and-metabolic-syndrome-on-the-incidence-of-loss-of-independence-in-community-dwelling-older-japanese-the-kusatsu-town-study
#18
Akihiko Kitamura, Shoji Shinkai, Yu Taniguchi, Hidenori Amano, Satoshi Seino, Yuri Yokoyama, Mariko Nishi, Yoshinori Fujiwara
Objectives To investigate the relationship between frailty, metabolic syndrome (MetS), and loss of independence leading to the onset of disability or death among community-dwelling older Japanese.Methods Between 2002 and 2011, we conducted a 7-year prospective study involving 1,453 residents aged 65 years and over, initially free of disability, who underwent a comprehensive geriatric assessment in Kusatsu town. Statistical analysis was conducted for those with complete values, resulting in a variable number of subjects for each data point...
2017: [Nihon Kōshū Eisei Zasshi] Japanese Journal of Public Health
https://www.readbyqxmd.com/read/29114605/diffuse-large-b-cell-lymphoma-in-very-elderly-patients-over-80-years-old-incorporating-consolidative-radiation-therapy-into-management-decisions
#19
Chelsea C Pinnix, Therese Y Andraos, Bouthaina Dabaja, Sarah Milgrom, Grace Smith, Dai Chihara, Andrea Ng, Luis E Fayad, Yasuhiro Oki, Sattva Neelapu, Jason Westin, M Alma Rodriguez, Loretta J Nastoupil
Purpose: The population of patients aged 80 years or older who are diagnosed with diffuse large B-cell lymphoma (DLBCL) continues to increase, but an optimal treatment strategy has not been established. We sought to examine the influence of consolidative radiation therapy (RT) on outcome and toxicity among the very elderly diagnosed with stage I-IV DLBCL. Methods and materials: We evaluated 131 patients treated at a single institution between 2002 and 2014 who were eligible for RT after successful treatment with chemotherapy...
July 2017: Advances in Radiation Oncology
https://www.readbyqxmd.com/read/29089225/rates-and-risk-factors-of-conversion-hip-arthroplasty-after-closed-reduction-percutaneous-hip-pinning-for-femoral-neck-fractures-a-population-analysis
#20
Cynthia A Kahlenberg, Shawn S Richardson, William W Schairer, Michael B Cross
BACKGROUND: Closed reduction with percutaneous pinning (CRPP) for nondisplaced or valgus impacted femoral neck fractures is a relatively low-risk operation that can produce excellent union rates in some patients; however, failure can occur in selected patients requiring conversion to arthroplasty. The primary aim of this study was to perform a population-level analysis to determine the rate and timeframe of conversion from CRPP to total hip arthroplasty (THA) or hemiarthroplasty. METHODS: The PearlDiver database was queried from 2007-2015 for all patients who underwent CRPP for a femoral neck fracture...
October 10, 2017: Journal of Arthroplasty
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