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Nicholas M Allen, Hormos S Dafsari, Elizabeth Wraige, Heinz Jungbluth
Neck-tongue syndrome is a rarely reported headache disorder characterized by occipital and/or upper neck pain triggered by sudden rotatory head movement and accompanied by abnormal sensation and/or posture of the ipsilateral tongue. Although onset is thought to be in childhood, most of the limited number of cases reported so far were adults. Here the authors describe 3 cases, 2 girls and 1 boy, with neck-tongue syndrome. In each child additional headache symptoms occurred, headache improved over time in all, spontaneously in 2 and coinciding with gabapentin treatment in the other...
April 2018: Journal of Child Neurology
Hormos Salimi Dafsari, Stefan Herzig, Jan Matthes
Aim: Initiated by students, this pilot study examines how obtaining medical students' perspectives via a structured online survey may prove useful for curriculum deliberation. Methods: In 2012, 747 students of 32 medical faculties in Germany assessed disciplines specified in the Medical Licensure Act (AÄpprO) thereby concerning the allocation of teaching time, perceived usefulness regarding preparation for state examination and medical practice, their interest and motivation for studying as well as consideration for future work...
2017: GMS Journal for Medical Education
Hormos Salimi Dafsari, Susan Byrne, Jean-Pierre Lin, Matthew Pitt, Jan Dh Jongbloed, Frances Flinter, Heinz Jungbluth
Goldberg-Shprintzen megacolon syndrome (GOSHS) (OMIM 609460) is characterized by a combination of learning difficulties, characteristic dysmorphic features and Hirschsprung's disease. Variable clinical features include iris coloboma, congenital heart defects and central nervous system abnormalities, in particular polymicrogyria. GOSHS has been attributed to recessive mutations in KIAA1279, encoding kinesin family member (KIF)-binding protein (KBP) with a crucial role in neuronal microtubule dynamics. Here we report on a 7-year-old girl with GOSHS as a result of a homozygous deletion of exons 5 and 6 of the KIAA1279 gene...
June 2015: American Journal of Medical Genetics. Part A
Marijke Van der Veen, Jacob Morales
ETHNOPHARMACOLOGICAL RELEVANCE: Tropical spices have long been utilized in traditional medicine and cuisine. New archaeological evidence highlights temporal changes in the nature and scale of the ancient spice trade and in the ancient usage of these plants. Furthermore, a study of their 'materiality' highlights that the impact of spices extends beyond their material properties. Here the botanical remains of spices recovered from archaeological excavations at a port active in the Roman and medieval Islamic spice trade are evaluated...
June 5, 2015: Journal of Ethnopharmacology
Andrea Camerini, Marianna Rondini, Ornella Garrone, Chiara Valsuani, Sara Donati, Olimpia Siclari, Alessandro Sgambato, Gianna Tartarelli, Maura Vincenti, Valentina Polla Mattiot, Romana Prosperi Porta, Cheti Puccetti, Paolo Puccinelli, Domenico Amoroso
BACKGROUND: Fulvestrant is a pure anti-estrogen hormoal agent formally lacking any estrogen-agonist activity. We analyze the effect(s) of fulvestrant treatment on estrogen target systems in hormoe-sensitive advanced breast cancer patients. RESULTS: Patients received a median of five fulvestrant injections (range 3-19). We observed a partial response in one patient, disease stability in 21 and disease progression in 29 patients with a clinical benefit of 43.2% and a median time to progression of 5 [range 3-20] mo...
August 2009: Cancer Biology & Therapy
Luigi Gennari
Hormos Medical is developing the selective estrogen receptor modulator ospemifene, for the potential treatment of postmenopausal osteoporosis and urogenital atrophy. By November 2003, Hormos had advanced the drug into phase II/III testing for both indications.
April 2004: Current Opinion in Investigational Drugs
No abstract text is available yet for this article.
September 1951: Revue Française de Gynécologie et D'obstétrique
No abstract text is available yet for this article.
April 1959: Zeitschrift Für Kreislaufforschung
L C Gasbarre
Gastrointestinal (GI) nematodes of ruminants evoke a wide variety of immune responses in their hosts. In terms of specific immune responses directed against parasite antigens, the resulting immune responses may vary from those that give strong protection from reinfection after a relatively light exposure (e.g. Oesophagostomum radiatum) to responses that are very weak and delayed in their onset (e.g. Ostertagia ostertagi). The nature of these protective immune responses has been covered in another section of the workshop and the purpose of this section will be to explore the nature of changes that occur in the immune system of infected animals and to discuss the effect of GI nematode infections upon the overall immunoresponsiveness of the host...
November 1997: Veterinary Parasitology
R Lamerz, A Leonhardt, H Ehrhart, H von Lieven
Serum CEA levels were determined in 2095 patients following mastectomy for breast cancer by means of a double antibody 125 I-CEA-radioimmunoassay. 91% of 1462 patients free of metastases had normal levels less than or equal to 3 ng/ml (98% less than or equal to 5 ng/ml). In contrast, 54% of 633 patients with overt metastases had raised values greater than 3 ng/ml (43% greater than 5 ng/ml). The incidence of pathological levels was dependent on tumour burden and metastatic location rising from solitary lymph node disease (6% greater than 5 ng/ml) to skin, lung, bone, liver and multiple organ involvement (60%)...
1980: Oncodevelopmental Biology and Medicine: the Journal of the International Society for Oncodevelopmental Biology and Medicine
R Vigneri, D Papalia, S Squatrito, Mottl
No abstract text is available yet for this article.
June 1970: Folia Endocrinologica
P Gellé, M Pauchant, M Dominatti, G Crépin, G Delahousse
No abstract text is available yet for this article.
January 1970: Bulletin de la Fédération des Sociétés de Gynécologie et Dóbstétrique de Langue Française
K Lundbaek
No abstract text is available yet for this article.
1973: Advances in Metabolic Disorders
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