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Partial knee arthroplasty

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https://www.readbyqxmd.com/read/28777797/alteration-of-wnt5a-expression-and-of-the-non-canonical-wnt-pcp-and-wnt-pkc-ca2-pathways-in-human-osteoarthritis-osteoblasts
#1
Xavier Martineau, Élie Abed, Johanne Martel-Pelletier, Jean-Pierre Pelletier, Daniel Lajeunesse
OBJECTIVE: Clinical and in vitro studies suggest that subchondral bone sclerosis due to abnormal osteoblasts (Ob) is involved in the progression and/or onset of osteoarthritis (OA). Human Ob isolated from sclerotic subchondral OA bone tissue show an altered phenotype, a decreased canonical Wnt/β-catenin signaling pathway (cWnt), and a reduced mineralization in vitro. In addition to the cWnt pathway, at least two non-canonical signaling pathways, the Wnt/PKC and Wnt/PCP pathway have been described...
2017: PloS One
https://www.readbyqxmd.com/read/28733109/reconstructing-the-chronically-disrupted-knee-extensor-mechanism-after-total-knee-arthroplasty-hourglass-variant-of-the-original-partial-allograft-technique
#2
C Fiquet, A Schneider, R Ballis, E Servien, P Neyret, S Lustig
Allograft reconstruction is a valuable treatment option for patients with chronic extensor mechanism disruption after total knee arthroplasty. Here, an hourglass variant of the original partial allografttechnique is described. An hourglass-shaped patellar bone block is press-fit into the native patella. The graft is fixed to both the patella and the tibia then sutured with the knee fully extended. Outcomes of this technique were assessed in 5 patients after at least 24 months' follow-up. The mean knee and function Knee Society Score values were 77...
July 18, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/28729762/combination-of-bone-marrow-mesenchymal-stem-cells-and-cartilage-fragments-contribute-to-enhanced-repair-of-osteochondral-defects
#3
Mohammed Abbas
Cartilage tissue engineering using stem cells and biomaterials is considered a promising approach despite poor outcomes. We hypothesise that articular cartilage fragments provides native environmental cues to enhance stem cell differentiation. As such we evaluated the chondrogenic differentiation and repair of critical size defect in a human explant osteochondral model (OD) using bone marrow derived mesenchymal stem cells (BM-MSCs) and homogenised cartilage. BM-MSCs were established from the bone-marrow plugs of patients undergoing total knee arthroplasty and characterized...
2017: Bioinformation
https://www.readbyqxmd.com/read/28691647/microbiological-diagnosis-in-revision-of-infected-knee-arthroplasties-in-denmark
#4
Martin Lindberg-Larsen, Frederik T Pitter, Marianne Voldstedlund, Henrik M Schrøder, Jens Bagger
BACKGROUND: Revision of infected knee arthroplasties is associated with high failure rates (30-40%). An understanding of the microbiology is important to optimize treatment and outcome. We describe microbiological diagnostic practice and diagnosis in revision of infected knee arthroplasties. METHODS: One hundred and two partial revisions (open debridement and exchange of tibial insert) and 213 two-stage procedures performed due to infection in 275 patients from 1 July 2011 to 30 June 2013 were included and analysed by linkage to data from a nationwide registry on microbiological test results...
July 8, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28664415/validation-of-three-dimensional-models-of-the-distal-femur-created-from-surgical-navigation-point-cloud-data-for-intraoperative-and-postoperative-analysis-of-total-knee-arthroplasty
#5
David A J Wilson, Carolyn Anglin, Felix Ambellan, Carl Martin Grewe, Alexander Tack, Hans Lamecker, Michael Dunbar, Stefan Zachow
PURPOSE: Despite the success of total knee arthroplasty, there continues to be a significant proportion of patients who are dissatisfied. One explanation may be a shape mismatch between pre- and postoperative distal femurs. The purpose of this study was to investigate methods suitable for matching a statistical shape model (SSM) to intraoperatively acquired point cloud data from a surgical navigation system and to validate these against the preoperative magnetic resonance imaging (MRI) data from the same patients...
June 29, 2017: International Journal of Computer Assisted Radiology and Surgery
https://www.readbyqxmd.com/read/28664261/the-fibular-head-projection-is-of-limited-use-as-a-radiographic-landmark-in-preoperative-planning-of-total-knee-arthroplasty
#6
Doerte Matziolis, Marius Meiser, Norbert Sieber, Ulf Teichgräber, Georg Matziolis
INTRODUCTION: The projection of the fibular head is recommended as a quality indicator of a correct radiographic projection. However, this landmark has yet to be sufficiently validated. METHODS: The MRIs of 334 knee joints were included. On the MRIs, the distance between the FH and lateral tibial cortical bone was simulated in projections parallel to surgically relevant axes. Then, the Pearson correlation coefficient between the distance of the FH to the lateral tibial cortical bone and the projection plane causing this was determined...
June 29, 2017: Skeletal Radiology
https://www.readbyqxmd.com/read/28657565/robotic-arm-assisted-partial-knee-arthroplasty-a-single-centre-experience
#7
Andrea Marcovigi, Francesco Zambianchi, Dario Sandoni, Elisa Rivi, Fabio Catani
BACKGROUND AND AIM OF THE WORK: UKA has proven to be an effective surgical procedure, but its survivorship is still negatively affected by inaccuracy in component component positioning, implant and limb alignment. Robotic surgery has been introduced in order to minimize such technical errors. The aim of the present paper was to evaluate clinical and surgical outcomes after a 3 years' experience of robotic assisted UKA with the Mako Robotic Arm. METHODS: Seventy-three patients undergoing  UKA with robotic instrumentation (65 medial UKAs, 8 lateral UKAs) and with a clinical follow-up of 3 -37 months were included in the present study...
June 7, 2017: Acta Bio-medica: Atenei Parmensis
https://www.readbyqxmd.com/read/28609474/effects-of-perceptions-of-care-medical-advice-and-hospital-quality-on-patient-satisfaction-after-primary-total-knee-replacement-a-cross-sectional-study
#8
Tom Schaal, Tonio Schoenfelder, Joerg Klewer, Joachim Kugler
INTRODUCTION: The increase in the number of patients presenting with osteoarthritis in the past decade has led to a 32% increase in knee replacement surgeries designed to reduce restrictions on patient movement and improve their quality of life. Patient satisfaction is becoming an increasingly important indicator of quality of care. This study was designed to identify predictors of various service components in the treatment process and hospital key performance indicators significantly associated with patient satisfaction...
2017: PloS One
https://www.readbyqxmd.com/read/28598492/use-of-2-octyl-cyanoacrylate-adhesive-and-polyester-mesh-for-wound-closure-in-primary-knee-arthroplasty
#9
Andrew J Holte, Josef N Tofte, Greta J Dahlberg, Nicolas Noiseux
Wound closure in primary knee arthroplasty is important both for surgical success, by minimizing the risk of wound complications and infection, and for patient satisfaction with wound care and cosmesis. This article reports the use of a topical self-adhering, pressure-sensitive polyester mesh combined with 2-octyl cyanoacrylate adhesive for final skin closure of primary knee arthroplasty without external staples or sutures. During a 2.5-year period, 360 consecutive primary knee arthroplasty procedures (321 total knee arthroplasty procedures and 39 partial knee arthroplasty procedures) performed by 1 surgeon at 1 institution were reviewed...
June 9, 2017: Orthopedics
https://www.readbyqxmd.com/read/28578839/the-combination-of-preoperative-bone-marrow-lesions-and-partial-thickness-cartilage-loss-did-not-result-in-inferior-outcomes-after-medial-unicompartmental-knee-arthroplasty
#10
Keith R Berend, Adolph V Lombardi, Cale A Jacobs
BACKGROUND: The purpose of this study is to compare patient-reported outcomes and revision rates between medial unicompartmental knee arthroplasty (UKA) patients based on the presence of medial bone marrow lesions (BMLs) and/or partial- vs full-thickness cartilage loss. METHODS: BMLs were graded on preoperative magnetic resonance imaging (MRI) findings from 174 UKAs performed between 2009 and 2013 using the MRI Osteoarthritis Knee Score criteria by a single evaluator blinded to the patient's outcome...
May 11, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28529858/hydrogen-peroxide-wound-irrigation-in-orthopaedic-surgery
#11
REVIEW
Min Lu, Erik Nathan Hansen
As the burden of deep hardware infections continues to rise in orthopaedics, there is increasing interest in strategies for more effective debridement of colonized tissues and biofilm. Hydrogen peroxide has been used medically for almost a century, but its applications in orthopaedic surgery have yet to be fully determined. The basic science and clinical research on the antiseptic efficacy of hydrogen peroxide have demonstrated its efficacy against bacteria, and it has demonstrated potential synergy with other irrigation solutions such as chlorhexidine and povidone-iodine...
2017: Journal of bone and joint infection
https://www.readbyqxmd.com/read/28514128/-treatment-for-osteoarthritis-of-the-knee
#12
REVIEW
Uriel Giwnewer, Guy Rubin, Hagay Orbach, Nimrod Rozen
Osteoarthritis is the most common joint disorder in the world and its incidence is rising. In Western populations it is one of the most frequent causes of pain, loss of function and disability in adults. The estimated lifetime risk for knee osteoarthritis is approximately 40% in men and 47% in women. The diagnosis of osteoarthritis is complex due to a lack of specific physical and/or laboratorial findings. The American College of Rheumatology (ACR) has recommended using the following criteria for the diagnosis of knee osteoarthritis: chronic knee pain (lasting for more than 6 weeks) and at least three of the following: • Age over 50 years old...
July 2016: Harefuah
https://www.readbyqxmd.com/read/28507975/charcot-fracture-in-the-calcaneus-after-total-knee-arthroplasty-a-case-report
#13
Hirokazu Takai, Katsuhiko Kiyota, Nobutake Nakane, Tomoki Takahashi
INTRODUCTION: Only a few reports have described calcaneus fractures after total knee arthroplasty (TKA). Therefore, in this report, we describe a case of calcaneal avulsion fracture that occurred 5 weeks after a TKA in a relatively young male patient with syphilis. CASE REPORT: A 63-year-old man with syphilis had Charcot joint of the right knee. The patient developed severe varus deformity and contracture and experienced severe pain in the knee. TKA was performed to alleviate the pain and improve the patient's gait...
November 2016: Journal of Orthopaedic Case Reports
https://www.readbyqxmd.com/read/28503126/in-vitro-and-ex-vivo-measurement-of-prophylactic-dabigatran-concentrations-with-a-new-ecarin-based-thromboelastometry-test
#14
Mareike Kristina Körber, Elisabeth Langer, Martin Köhr, Klaus-Dieter Wernecke, Wolfgang Korte, Christian von Heymann
BACKGROUND: An increasing number of oral anticoagulants has been approved, including dabigatran etexilate (DE). DE is a direct thrombin inhibitor that requires no routine monitoring, but, if necessary (e.g. urgent surgery etc.), the diluted thrombin time measured with Hemoclot® has shown reliable results. So far, no point-of-care (PoC) assay is available to measure DE effects. The EcaTEM assay uses ecarin to initiate the coagulation cascade at the step of thrombin generation and measures the clotting time (CT) by thromboelastometry...
April 2017: Transfusion Medicine and Hemotherapy
https://www.readbyqxmd.com/read/28473962/associations-among-pain-catastrophizing-muscle-strength-and-physical-performance-after-total-knee-and-hip-arthroplasty
#15
Kazuhiro Hayashi, Masato Kako, Kentaro Suzuki, Keiko Hattori, Saori Fukuyasu, Koji Sato, Izumi Kadono, Tadahiro Sakai, Yukiharu Hasegawa, Yoshihiro Nishida
AIM: To investigate whether reductions in pain catastrophizing associated with physical performance in the early period after total knee arthroplasty (TKA) or total hip arthroplasty (THA). METHODS: The study group of 46 participants underwent TKA or THA. The participants were evaluated within 7 d before the operation and at 14 d afterwards. Physical performance was measured by the Timed Up and Go (TUG) test, and 10-m gait time was measured at comfortable and maximum speeds...
April 18, 2017: World Journal of Orthopedics
https://www.readbyqxmd.com/read/28385936/unsatisfactory-outcomes-following-unicompartmental-knee-arthroplasty-in-patients-with-partial-thickness-cartilage-loss-a-medium-term-follow-up
#16
T W Hamilton, H G Pandit, A Inabathula, S J Ostlere, C Jenkins, S J Mellon, C A F Dodd, D W Murray
AIMS: While medial unicompartmental knee arthroplasty (UKA) is indicated for patients with full-thickness cartilage loss, it is occasionally used to treat those with partial-thickness loss. The aim of this study was to investigate the five-year outcomes in a consecutive series of UKAs used in patients with partial thickness cartilage loss in the medial compartment of the knee. PATIENTS AND METHODS: Between 2002 and 2014, 94 consecutive UKAs were undertaken in 90 patients with partial thickness cartilage loss and followed up independently for a mean of six years (1 to 13)...
April 2017: Bone & Joint Journal
https://www.readbyqxmd.com/read/28378003/ultrasound-gel-minimizes-third-body-debris-with-partial-hardware-removal-in-joint-arthroplasty
#17
Aidan C McGrory, Lee Replogle, Donald Endrizzi
Hundreds of thousands of revision surgeries for hip, knee, and shoulder joint arthroplasties are now performed worldwide annually. Partial removal of hardware during some types of revision surgeries may create significant amounts of third body metal, polymer, or bone cement debris. Retained debris may lead to a variety of negative health effects including damage to the joint replacement. We describe a novel technique for the better containment and easier removal of third body debris during partial hardware removal...
March 2017: Arthroplasty Today
https://www.readbyqxmd.com/read/28372918/all-polyethylene-tibial-component-use-for-elderly-low-demand-total-knee-arthroplasty-patients
#18
Kenneth A Gustke, Martin K Gelbke
BACKGROUND: Potential advantages combined with lower cost have prompted a renewed interest in modern all-polyethylene tibial designs. METHODS: A total of 317 Natural Knee total knee arthroplasties with an all-polyethylene tibial component that was performed since 1993 were retrospectively reviewed to confirm that cost savings were not associated with inferior clinical results. They were primarily used in elderly, low-demand patients. The average age at the time of surgery was 80...
March 8, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28371786/assessment-of-gait-characteristics-in-total-knee-arthroplasty-patients-using-a-hierarchical-partial-least-squares-method
#19
Wei Wang, David Ackland, Jodie McClelland, Kate E Webster, Saman Halgamuge
Quantitative gait analysis is an important tool in objective assessment and management of total knee arthroplasty (TKA) patients. Studies evaluating gait patterns in TKA patients have tended to focus on discrete data such as spatiotemporal information, knee range of motion and peaks in kinematics and kinetics, or consider selected principal components of gait waveforms for analysis. These strategies may not have the capacity to capture small variations in gait patterns associated with each joint across an entire gait cycle, and may ultimately limit the accuracy of gait classification...
March 30, 2017: IEEE Journal of Biomedical and Health Informatics
https://www.readbyqxmd.com/read/28347691/workers-perspectives-on-return-to-work-after-total-knee-arthroplasty
#20
Pascale Maillette, Marie-France Coutu, Nathaly Gaudreault
OBJECTIVES: Total knee arthroplasty is an effective intervention for people with osteoarthritis. However, 15 to 30% of patients do not return to work, and studies frequently fail to provide an explanation of what may lead to work disability from workers' perspectives of the biopsychosocial factors. This study aimed to document workers' representations or understanding of work disability after total knee arthroplasty. METHOD: We adopted a qualitative approach with a narrative inquiry method...
March 24, 2017: Annals of Physical and Rehabilitation Medicine
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