Di Zhu, Chenglin Jia, Tongkai Cai, Jiacheng Li, Xia Feng, Nan Chen, Cheng Zhao, Yuzhen Wang, Yongbing Cao, Yemin Cao
Ruan jian qing mai recipe (RJQM) is an empirical prescription for treating arteriosclerosis obliterans (ASO). However, the mechanism of RJQM recipe-mediated ASO attenuation has not yet been elucidated. Therefore, this study aimed to explore the mechanism by which the RJQM recipe relieves ASO in a mouse model of lower limb ischemia, which was established by ligating and breaking the femoral artery of the left lower limb. The surgical groups were divided into the ischemic group, beraprost sodium group, low-dose RJQM group, medium-dose RJQM group, and high-dose RJQM group...
2022: Evidence-based Complementary and Alternative Medicine: ECAM