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https://www.readbyqxmd.com/read/29244019/prevalence-healthcare-resource-utilization-and-overall-burden-of-fungal-meningitis-in-the-united-states
#1
Lefko T Charalambous, Alykhan Premji, Caroline Tybout, Anastasia Hunt, Drew Cutshaw, Aladine A Elsamadicy, Siyun Yang, Jichun Xie, Charles Giamberardino, Promila Pagadala, John R Perfect, Shivanand P Lad
PURPOSE: Previous epidemiological and cost studies of fungal meningitis have largely focused on single pathogens, leading to a poor understanding of the disease in general. We studied the largest and most diverse group of fungal meningitis patients to date, over the longest follow-up period, to examine the broad impact on resource utilization within the United States. METHODOLOGY: The Truven Health Analytics MarketScan database was used to identify patients with a fungal meningitis diagnosis in the United States between 2000 and 2012...
December 15, 2017: Journal of Medical Microbiology
https://www.readbyqxmd.com/read/29243513/evaluation-of-health-care-costs-and-utilization-for-patients-with-gout-a-population-based-matched-cohort-study
#2
Yi-Yun Lee, Chao-Hsiun Tang, Jin-Hua Chen, Li-Na Kuo, Yu Ko
OBJECTIVES: To better understand the economic burden of gout patients in Taiwan, we conducted a nationwide retrospective study to compare the healthcare costs and utilization between gout and gout-free patients. METHODS: The Longitudinal Health Insurance Database (LHID) 2010 was used to identify gout cases and matched gout-free controls. Gout cases were defined as having (1) at least three instances of diagnoses of gout on medical claims or (2) one diagnosis of gout with at least one gout-related pharmacy claim in 2011...
December 15, 2017: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/29242752/out-of-pocket-expenditures-for-prevention-and-treatment-of-cardiovascular-disease-in-general-and-specialised-cardiac-hospitals-in-addis-ababa-ethiopia-a-cross-sectional-cohort-study
#3
Mieraf Taddesse Tolla, Ole Frithjof Norheim, Stéphane Verguet, Abebe Bekele, Kassahun Amenu, Senbeta Guteta Abdisa, Kjell Arne Johansson
Background: Cardiovascular disease poses a great financial risk on households in countries without universal health coverage like Ethiopia. This paper aims to estimate the magnitude and intensity of catastrophic health expenditure and factors associated with catastrophic health expenditure for prevention and treatment of cardiovascular disease in general and specialised cardiac hospitals in Addis Ababa. Methods and findings: We conducted a cross-sectional cohort study among individuals who sought cardiovascular disease care in selected hospitals in Addis Ababa during February to March 2015 (n=589, response rate 94%)...
2017: BMJ Global Health
https://www.readbyqxmd.com/read/29241474/optimising-design-and-cost-effective-implementation-of-future-pan-african-dietary-studies-a-review-of-existing-economic-integration-and-nutritional-indicators-for-scenario-based-profiling-and-clustering-of-countries
#4
Elom K Aglago, Edwige Landais, Francis Zotor, Genevieve Nicolas, Marc J Gunter, Paul Amuna, Nadia Slimani
Most of the African countries are undergoing a complex nutrition and epidemiologic transition associated with a rapid increase in the prevalence of diverse non-communicable diseases. Despite this alarming situation, the still limited and fragmented resources available in Africa impede the implementation of effective action plans to tackle the current and projected diet-disease burden. In order to address these common needs and challenges, the African Union is increasingly supporting continental approaches and strategies as reflected in the launching of the Agenda 2063 and the African regional nutrition strategy 2015-2025, among others...
December 15, 2017: Proceedings of the Nutrition Society
https://www.readbyqxmd.com/read/29240805/poly-victimization-in-a-norwegian-adolescent-population-prevalence-social-and-psychological-profile-and-detrimental-effects
#5
Svein Mossige, Lihong Huang
BACKGROUND: This study focuses on poly-victimization, with the aim of providing a realistic estimation of the prevalence of lifetime victimization in a Norwegian adolescent population (ages 18-19 years). METHODS: Based upon the concept from previous research, we applied measures of child poly-victimization on Norwegian data obtained from a national youth survey in 2015 (N = 4,531) to arrive at an estimation of its prevalence. We used variables that measure individual characteristics such as gender and educational aspiration and socio-economic factors such as parents' education level and home economic situation to derive a social and psychological profile of victimization and poly-victimization among young people...
2017: PloS One
https://www.readbyqxmd.com/read/29240298/diabetic-macular-edema-innovative-technologies-and-economic-impact-new-opportunities-for-the-lombardy-region-healthcare-system
#6
Emanuela Foglia, Lucrezia Ferrario, Francesco Bandello, Camilla Ferri, Innocente Figini, Michela Franzin, Gianpiera Gambaro, Ugo Introini, Massimo Medaglia, Giovanni Staurenghi, Patrizia Tadini, Andrea Fomiatti, Davide Croce
PURPOSE: Diabetic macular edema (DME) is a leading cause of vision loss and blindness. The aim of this study was to evaluate the economic benefits of introducing additional alternative technologies (Dexamethasone intravitreal implant - DEX - and Aflibercept injections), compared with the historical scenario of Ranibizumab intravitreal injections. METHODS: A 3-year budget impact model was developed, taking into consideration the perspective of the Lombardy Region Healthcare Service (LRHS)...
December 14, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/29238484/pattern-and-factors-associated-with-cardiovascular-diseases-among-patients-attending-the-cardiac-center-in-arar-city-northern-saudi-arabia
#7
Fatimah Fahad Altaleb, Othman Mashfi Alshammari, Hala Mohammed Alanazi, Dina Anwar Aljaber, Arwa Bader Alanazi, Nagah Mohamed Abo El-Fetoh, Nesreen Ali Mohammed, Hadil Anwar Aljaber
Background: Cardiovascular diseases (CVD) are among the main causes of premature death and hospital admission worldwide, constituting a great economic burden on health care systems. Additionally, thyroid diseases may exert a deleterious effect on the outcomes of CVD patients. Aim: This study was conducted to identify the pattern and factors associated with CVD distribution and the relation with thyroid dysfunction in the study population. Methods: This cross sectional study was conducted on 181 participants in the cardiac center in Arar, Kingdom of Saudi Arabia (KSA), from September 2016 to March 2017...
October 2017: Electronic Physician
https://www.readbyqxmd.com/read/29238392/risk-for-depression-burnout-and-low-quality-of-life-among-personnel-of-a-university-hospital-in-italy-is-a-consequence-of-the-impact-one-economic-crisis-in-the-welfare-system
#8
M G Carta, A Preti, I Portoghese, E Pisanu, D Moro, M Pintus, E Pintus, A Perra, S D'Oca, M Atzeni, M Campagna, E Fabrici Pascolo, F Sancassiani, G Finco, E D'Aloja, L Grassi
Background: Research literature suggests that burnout, depression, and a low mental quality of life (QOL) are common among health care workers. Economic crisis might have increased the burden of burnout, depression and low QOL in health care workers. Objectives: To identify depression risk, burnout levels, and quality of life in a sample of workers of an Italian university hospital. Method: Cross sectional study with comparison with two community surveys database results (n = 2000 and 1500, respectively)...
2017: Clinical Practice and Epidemiology in Mental Health: CP & EMH
https://www.readbyqxmd.com/read/29237442/factors-impacting-the-illness-trajectory-of-post-infectious-fatigue-syndrome-a-qualitative-study-of-adults-experiences
#9
Eva Stormorken, Leonard A Jason, Marit Kirkevold
BACKGROUND: Post-infectious fatigue syndrome (PIFS), also known as post-viral fatigue syndrome, is a complex condition resulting in physical, cognitive, emotional, neurological, vocational and/or role performance disabilities in varying degrees that changes over time. The needs for health care resources are high, and costly, as is the economic burden on the affected individuals. Many factors may impact the trajectory, and frequently PIFS develops into a chronic condition. Health professionals lack understanding and knowledge, which results in delayed diagnosis, lack of recognition, appropriate treatment, support and practical help...
December 13, 2017: BMC Public Health
https://www.readbyqxmd.com/read/29236741/social-determinants-of-adult-mortality-from-non-communicable-diseases-in-northern-ethiopia-2009-2015-evidence-from-health-and-demographic-surveillance-site
#10
Semaw Ferede Abera, Alemseged Aregay Gebru, Hans Konrad Biesalski, Gebisa Ejeta, Andreas Wienke, Veronika Scherbaum, Eva Johanna Kantelhardt
INTRODUCTION: In developing countries, mortality and disability from non-communicable diseases (NCDs) is rising considerably. The effect of social determinants of NCDs-attributed mortality, from the context of developing countries, is poorly understood. This study examines the burden and socio-economic determinants of adult mortality attributed to NCDs in eastern Tigray, Ethiopia. METHODS: We followed 45,982 adults implementing a community based dynamic cohort design recording mortality events from September 2009 to April 2015...
2017: PloS One
https://www.readbyqxmd.com/read/29235706/a-conserved-tad-pilus-promotes-vibrio-vulnificus-oyster-colonization
#11
Meng Pu, Patrick Duriez, Mattan Arazi, Dean A Rowe-Magnus
Vibrio vulnificus has the highest death rate (>35%) and per-case economic burden ($3.3 million) of any foodborne pathogen in the US. Infections occur via open wounds or following ingestion of contaminated seafood, most infamously oysters. We isolated a 1000th generation descendant, designated NT, that exhibited increased biofilm and aggregate formation relative to its parent. We identified two significant causal changes underlying these NT phenotypes. First, the entire 24-kb capsular polysaccharide biosynthesis locus, which is essential for virulence but inhibits biofilm formation, had been purged from the genome...
December 13, 2017: Environmental Microbiology
https://www.readbyqxmd.com/read/29235433/annual-prevalence-and-economic-burden-of-genital-warts-in-korea-health-insurance-review-and-assessment-hira-service-data-from-2007-to-2015
#12
Y J Park, J M Kim, B R Lee, T H Kim, E G Lee
This study evaluated the annual prevalence of anogenital warts (AGW) caused by human papillomavirus (HPV) and analysed the trend in annual per cent changes (APC) by using national claims data from the Health Insurance Review and Assessment of Korea, 2007-2015. We also estimated the socio-economic burden and co-morbidities of AGW. All analyses were performed based on data for primary A63.0, the specific diagnosis code for AGW. The socio-economic cost of AGW was calculated based on the direct medical cost, direct non-medical cost and indirect cost...
December 13, 2017: Epidemiology and Infection
https://www.readbyqxmd.com/read/29234227/eradicating-primary-congenital-glaucoma-from-saudi-arabia-the-case-for-a-national-screening-program
#13
REVIEW
Rizwan Malik, Rajiv Khandekar, Trishal Boodhna, Zuhair Rahbeeni, Abdul Elah Al Towerki, Deepak P Edward, Khaled Abu-Amero
The prevalence of primary congenital glaucoma (PCG) in Saudi Arabia is high and the condition is a cause of childhood blindness in the country. Children often present with severe disease, requiring multiple procedures and a lifetime of medical care. The social and economic burden of the condition is substantial. Presently, the mainstay of management is early diagnosis and treatment of PCG. Premarital screening, especially in recessive diseases, such as PCG can be immensely useful by detecting the presence of a defect in the causative gene, followed by genetic counseling to potential couples that will lead to eradication of the disease in future generations...
October 2017: Saudi Journal of Ophthalmology: Official Journal of the Saudi Ophthalmological Society
https://www.readbyqxmd.com/read/29234121/in-silico-modelling-to-differentiate-the-contribution-of-sugar-frequency-versus-total-amount-in-driving-biofilm-dysbiosis-in-dental-caries
#14
David Head, Deirdre A Devine, P D Marsh
Dental caries is the most prevalent infection globally and a substantial economic burden in developed countries. Dietary sugars are the main risk factor, and drive increased proportions of acid-producing and acid-tolerating (aciduric) bacterial species within dental biofilms. Recent longitudinal studies have suggested that caries is most strongly correlated with total sugar intake, contrasting with the prevailing view that intake frequency is the primary determinant. To explore this possibility, we employed a computational model for supragingival plaque to systematically sample combinations of sugar frequency and total amount, allowing their independent contributions on the ratio of aciduric (i...
December 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29233687/interferon-free-direct-acting-antiviral-therapy-for-acute-hepatitis-c-virus-infection-in-hiv-infected-individuals-a-literature-review
#15
REVIEW
Temi Lampejo, Kosh Agarwal, Ivana Carey
Dramatic rises in hepatitis C virus (HCV) coinfection rates in human immunodeficiency virus (HIV)-infected individuals have been observed recently, largely attributable to increasing recreational drug use combined with increased testing for HCV. In the era of direct-acting antiviral (DAA) therapy, treatment of acute HCV infection in HIV-infected individuals with short durations of these drugs may potentially reduce the disease and economic burden associated with HCV infection as well as reducing the likelihood of onward HCV transmission...
November 27, 2017: Digestive and Liver Disease
https://www.readbyqxmd.com/read/29233202/thinness-in-young-schoolchildren-in-serbia-another-case-of-the-double-burden-of-malnutrition
#16
Visnja Djordjic, Jagoda Jorga, Snezana Radisavljevic, Ivana Milanovic, Predrag Bozic, Sergej M Ostojic
OBJECTIVE: Thinness is rarely highlighted or regularly monitored among children in developed countries although it may be rather frequent and pose a significant risk to children's health. We aimed to describe the prevalence of mild, moderate and severe thinness among young Serbian schoolchildren. DESIGN: Cross-sectional study of schoolchildren aged 6-9 years. Children were assessed for weight, height and BMI as part of the WHO European Childhood Obesity Surveillance Initiative in Serbia...
December 13, 2017: Public Health Nutrition
https://www.readbyqxmd.com/read/29233136/socioeconomic-inequality-in-abdominal-obesity-among-older-people-in-purworejo-district-central-java-indonesia-a-decomposition-analysis-approach
#17
Cahya Utamie Pujilestari, Lennarth Nyström, Margareta Norberg, Lars Weinehall, Mohammad Hakimi, Nawi Ng
BACKGROUND: Obesity has become a global health challenge as its prevalence has increased globally in recent decades. Studies in high-income countries have shown that obesity is more prevalent among the poor. In contrast, obesity is more prevalent among the rich in low- and middle-income countries, hence requiring different focal points to design public health policies in the latter contexts. We examined socioeconomic inequalities in abdominal obesity in Purworejo District, Central Java, Indonesia and identified factors contributing to the inequalities...
December 12, 2017: International Journal for Equity in Health
https://www.readbyqxmd.com/read/29232939/clinical-and-economic-analysis-of-the-2009-h1n1-influenza-pandemic-among-pregnant-korean-women
#18
Won Suk Choi, Min Joo Choi, Ji Yoon Noh, Joon Young Song, Woo Joo Kim, Dae Won Park, Jacob Lee, Yu Bin Seo, Ji Hyeon Baek, Sooran Choi, Hee Jin Cheong
Background/Aims: Unlike Western countries, the 2009 pandemic influenza infection among pregnant women was reported as mild in a previous interim study in South Korea. However, several mortalities were reported thereafter, suggesting that nationwide data were lacking. Methods: This case-control study covers the entire 2009 pandemic inf luenza period, from May 2009 to February 2010. The clinical and economic data of pregnant (case) and age-matched non-pregnant (control) women with influenza A (H1N1) pdm09 virus (H1N1pdm09) infection were retrospectively collected from nine hospitals in South Korea...
December 15, 2017: Korean Journal of Internal Medicine
https://www.readbyqxmd.com/read/29232698/low-energy-extracorporeal-shockwave-therapy-eswt-improves-metaphyseal-fracture-healing-in-an-osteoporotic-rat-model
#19
Gina A Mackert, Matthias Schulte, Christoph Hirche, Dimitra Kotsougiani, Julian Vogelpohl, Bernd Hoener, Teresa Fiebig, Stefanie Kirschner, Marc A Brockmann, Marcus Lehnhardt, Ulrich Kneser, Leila Harhaus
PURPOSE: As result of the current demographic changes, osteoporosis and osteoporotic fractures are becoming an increasing social and economic burden. In this experimental study, extracorporeal shock wave therapy (ESWT), was evaluated as a treatment option for the improvement of osteoporotic fracture healing. METHODS: A well-established fracture model in the metaphyseal tibia in the osteoporotic rat was used. 132 animals were divided into 11 groups, with 12 animals each, consisting of one sham-operated group and 10 ovariectomized (osteoporotic) groups, of which 9 received ESWT treatment...
2017: PloS One
https://www.readbyqxmd.com/read/29230311/household-water-insecurity-missed-schooling-and-the-mediating-role-of-caregiver-depression-in-rural-uganda
#20
C E Cooper-Vince, B Kakuhikire, D Vorechovska, A Q McDonough, J Perkins, A S Venkataramani, R C Mushavi, C Baguma, S Ashaba, D R Bangsberg, A C Tsai
Background: School attendance rates in sub-Saharan Africa are among the lowest worldwide, placing children at heightened risk for poor educational and economic outcomes. One understudied risk factor for missed schooling is household water insecurity, which is linked to depression among women and may increase children's water-fetching burden at the expense of educational activities, particularly among children of depressed caregivers. In this study conducted in rural Uganda, we assessed the association between household water insecurity and child school participation and the mediating pathways behind these associations...
2017: Global Mental Health
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