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https://www.readbyqxmd.com/read/28934778/the-effect-of-early-use-of-supplemental-therapy-on-preventing-postherpetic-neuralgia-a-systematic-review-and-meta-analysis
#1
Xiu-Fang Xing, Zhen-Feng Zhou, Feng-Jiang Zhang, Min Yan
BACKGROUND: Postherpetic neuralgia (PHN) is the most common and refractory complication of herpes zoster (HZ). Aggressive treatment of acute pain in HZ has the potential to prevent the development of PHN, but the preventive efficacy of supplemental therapy commonly used in clinical practice is controversial. OBJECTIVES: Our aim is to examine the efficacy of supplemental therapy in preventing PHN. STUDY DESIGN: A meta-analysis. SETTING: All of the selected studies are randomized controlled trials (RCTs)...
September 2017: Pain Physician
https://www.readbyqxmd.com/read/28933307/the-role-of-xanthine-oxidase-inhibitors-in-patients-with-history-of-stroke-a-systematic-review
#2
Sara R Britnell, Kelly A Chillari, Jamie N Brown
BACKGROUND: Xanthine oxidase inhibitors are commonly used to lower uric acid levels in patients with gout. Due to their effects on endothelial function, they have also been investigated for possible benefits for patients with cardiovascular disease. OBJECTIVE: To assess the efficacy and safety of xanthine oxidase inhibitors in the treatment of patients with history of stroke. METHODS: MEDLINE (1946-June 2017) and EMBASE (1947-June 2017) were queried using the search terms: "allopurinol" OR "febuxostat" OR "xanthine oxidase inhibitor" OR "xanthine oxidase/antagonists and inhibitors" AND "stroke" OR "cerebral infarction" OR "cerebrovascular accident"...
September 19, 2017: Current Vascular Pharmacology
https://www.readbyqxmd.com/read/28933135/headache-in-a-young-woman-do-not-forget-susac-s-syndrome
#3
A Kefi, F Said, T Ben Salem, M Khedher, M Khanfir, I Ben Ghorbel, M Lamloum, M H Houman
Susac syndrome is a rare disease characterized by the clinical triad of encephalopathy, branch retinal artery occlusion, and sensorineural hearing loss. This underdiagnosed condition needs to be considered in the differential diagnosis of a broad variety of disorders. An early diagnosis is important as treatment can halt disease progression and prevent permanent disability. Herein, we report a case of Susac syndrome in a 31-year-old woman and we highlight how challenging an early diagnosis was and the importance of an aggressive therapeutic approach, including the combination of steroids and other cytotoxic drugs...
September 21, 2017: Reumatismo
https://www.readbyqxmd.com/read/28932964/treatment-strategies-for-the-opioid-dependent-patient
#4
REVIEW
Shweta Teckchandani, Meredith Barad
PURPOSE OF REVIEW: This review is intended to help the headache physician think through and plan for management issues concerning the use of opioids. We ask the headache physician to consider if there are instances where prescribing or continuing prescriptions of opiates is plausible, and if so, how can the physician proceed as safely as possible. Our goal is to start a conversation regarding the inevitable encounter with a patient on opiates or requesting opiates. RECENT FINDINGS: The use of opiates in our society has reached a crisis in staggering death and addiction rates...
September 20, 2017: Current Pain and Headache Reports
https://www.readbyqxmd.com/read/28932685/pig-s-ear-streptococcus-suis-meningitis-and-its-associated-inner-ear-implications
#5
S Sena Esteves, J Carvalho de Almeida, J Abrunhosa, C Almeida E Sousa, Q Arshad
Streptococcus suis (S. suis) is a zoonotic pathogen commonly found in Asian countries. Infection with this bacterium typically clinically presents as meningitis and individuals whom handle swine are at increased risk of developing infections. We present a case of a patient with a S. suis meningitis who worked as a butcher. The 48-year-old man was admitted to our department with headaches, fevers, nausea and bilateral hearing loss. According to his medical history, the patient had sustained a cut on his finger while preparing pork meat...
2017: IDCases
https://www.readbyqxmd.com/read/28932391/photophobia-in-neurologic-disorders
#6
REVIEW
Yiwen Wu, Mark Hallett
Photophobia is a common symptom seen in many neurologic disorders, however, its pathophysiology remains unclear. Even the term is ambiguous. In this paper, we review the epidemiology and clinical manifestations of photophobia in neurological disorders, including primary headache, blepharospasm, progressive supranuclear palsy, and traumatic brain injury, discuss the definition, etiology and pathogenesis, and summarize practical methods of diagnosis and treatment.
2017: Translational Neurodegeneration
https://www.readbyqxmd.com/read/28932372/acupuncture-and-botulinum-toxin-a-injection-in-the-treatment-of-chronic-migraine-a-randomized-controlled-study
#7
Bahram Naderinabi, Alia Saberi, Masood Hashemi, Mohammad Haghighi, Gelareh Biazar, Farid Abolhasan Gharehdaghi, Abbas Sedighinejad, Tahereh Chavoshi
BACKGROUND: Migraine is a common type of headache. Sometimes adequate pain relief is not achieved by conventional treatments. Acupuncture and botulinum toxin-A injection are known as non-pharmacological interventions for this purpose. The aim of this research was to compare the effect of acupuncture with botulinum toxin-A injection and pharmacological treatment in controlling chronic migraine. METHODS: This clinical trial was conducted on patients with chronic migraine in the North of Iran during 2014-2015...
2017: Caspian Journal of Internal Medicine
https://www.readbyqxmd.com/read/28932362/clinical-radiological-pathological-correlation-of-cavernous-sinus-hemangioma-incremental-value-of-diffusion-weighted-imaging
#8
Abhishek Mahajan, Vedula Rajni Kanth Rao, Gudipati Anantaram, Ashwin M Polnaya, Sandeep Desai, Paresh Desai, Rammohan Vadapalli, Manas Panigrahi
AIM: To elucidate the clinical, magnetic resonance imaging (MRI), pathological features of these lesions and asses the incremental value of diffusion-weighted imaging (DWI) in diagnosing them. METHODS: Fifteen consecutive patients (11 females and 4 males; mean age 40.93 years; age range 13-63 years) with cavernous sinus hemangiomas (CSH) who underwent examination between November 2008 and May 2016 were included for the analysis. MRI, clinical and surgical findings of each patient was retrospectively reviewed...
August 28, 2017: World Journal of Radiology
https://www.readbyqxmd.com/read/28931491/global-regional-and-national-burden-of-neurological-disorders-during-1990-2015-a-systematic-analysis-for-the-global-burden-of-disease-study-2015
#9
(no author information available yet)
BACKGROUND: Comparable data on the global and country-specific burden of neurological disorders and their trends are crucial for health-care planning and resource allocation. The Global Burden of Diseases, Injuries, and Risk Factors (GBD) Study provides such information but does not routinely aggregate results that are of interest to clinicians specialising in neurological conditions. In this systematic analysis, we quantified the global disease burden due to neurological disorders in 2015 and its relationship with country development level...
September 15, 2017: Lancet Neurology
https://www.readbyqxmd.com/read/28931106/a-case-of-prethoracic-pain-radiating-upward-and-initiating-nervus-intermedius-neuralgia-and-migraine-headache-could-epicrania-fugax-pain-start-in-the-upper-body
#10
Yu Wang, Pei-Lin Kan, Yuan-Feng Tao, Xiao-Yan Li, Xiao-Juan Yang, Gui-Ling Liang
Epicrania fugax (EF) was recently classified as a primary headache in the Appendix of the International Classification of Headache Disorders, third edition (ICHD-III). It is characterized by a paroxysmal pain rapidly radiating forward or backward along a linear or zigzag trajectory on the surface of the head. This article reports a 76-year-old woman who newly developed a paroxysmal EF-type pain distributed not only in the territories of the trigeminal and occipital nerves, but also in the territories of the cervical and thoracic nerves...
September 20, 2017: Journal of Oral & Facial Pain and Headache
https://www.readbyqxmd.com/read/28931105/neurofibromatosis-type-1-accompanied-by-craniofacial-pain-literature-review-and-descriptive-case
#11
Chunghwan Son, Ji Woon Park
Neurofibromatosis type 1 (NF-1) is a genetic disease with characteristic neurofibromas and bony dysplasia that manifest throughout the body, including the craniofacial region. NF-1 patients are known to frequently report chronic pain in areas below the head; however, the matter of pain in the craniofacial region in this patient group has not been handled intensively so far, and studies have mainly focused on headaches. This article comprehensively reviews the related literature and reports a case of an NF-1 patient whose chief complaint was headache and pain in the temporomandibular joint area...
September 20, 2017: Journal of Oral & Facial Pain and Headache
https://www.readbyqxmd.com/read/28930248/the-effect-of-acupuncture-on-visual-function-in-patients-with-congenital-and-acquired-nystagmus
#12
Tilo Blechschmidt, Maike Krumsiek, Margarita G Todorova
Background: The aim of this study is to examine the short-term effect of visual function following acupuncture treatment in patients with congenital idiopathic nystagmus and acquired nystagmus (CIN and AN). Methods: An observational pilot study on six patients with confirmed diagnosis of nystagmus (three CIN and three AN patients (2♀, 4♂; mean age 42.67; SD ± 20.57 y)), was performed. Acupuncture treatment was done following a standardized protocol applying needle-acupuncture on the body and the ears. The treatment was scheduled with 10 sessions of 30 min duration over five weeks...
May 23, 2017: Medicines (Basel, Switzerland)
https://www.readbyqxmd.com/read/28930006/fatal-rocky-mountain-spotted-fever-along-the-united-states-mexico-border-2013-2016
#13
Naomi A Drexler, Hayley Yaglom, Mariana Casal, Maria Fierro, Paula Kriner, Brian Murphy, Anne Kjemtrup, Christopher D Paddock
Rocky Mountain spotted fever (RMSF) is an emerging public health concern near the US-Mexico border, where it has resulted in thousands of cases and hundreds of deaths in the past decade. We identified 4 patients who had acquired RMSF in northern Mexico and subsequently died at US healthcare facilities. Two patients sought care in Mexico before being admitted to US-based hospitals. All patients initially had several nonspecific signs and symptoms, including fever, headache, nausea, vomiting, or myalgia, but deteriorated rapidly without receipt of a tetracycline-class antimicrobial drug...
October 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/28929668/-systematic-review-on-safety-of-sofren-injection
#14
Yi Que, Yan-Ming Xie, Xing Liao, Yi-Li Zhang
This systematic review aims to evaluate the drug safety of sofren injection in clinical studies. Seven databases were retrieved, and the articles were extracted by 2 researchers according to inclusion and exclusion criteria. Then the quality of all studies and extracted information was evaluated. Sixty three articles were finally included in our study, including 58 randomized controlled trials, 3 non randomized controlled trials, and 2 case reports. All studies included 5 872 patients. Intervention group had a total of 23 cases of adverse drug reaction(ADR), accounting for 0...
October 2016: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/28929666/-32-546-intensive-hospital-monitoring-cases-of-shuxuetong-injection
#15
Jun-Jie Jiang, Yan-Ming Xie, Yin Zhang, Zhi-Xin Yang, Dan-Hui Yi
This study adopted multi-center and large sample design to understand the incidence, characteristics and other information about adverse reaction of Shuxuetong injection. In 54 medical institutions, use of Shuxuetong injection of entire treatment period was monitored, including patients' general information, diagnostic information, medication, adverse reaction/event information, etc. Sixty four cases of adverse reactions in 32 546 patients was monitored, adverse rate was 0.197%, mainly characterized by skin itching, rash, flu-like, dyspnea, palpitations, headache, chest tightness and other allergic reactions...
October 2016: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/28929534/emerging-arboviruses-in-rio-grande-do-sul-brazil-chikungunya-and-zika-outbreaks-2014-2016
#16
Tatiana Schäffer Gregianini, Tani Ranieri, Cátia Favreto, Zenaida Marion Alves Nunes, Gabriela Luchiari Tumioto Giannini, Nara Druck Sanberg, Marilda Tereza Mar da Rosa, Ana Beatriz Gorini da Veiga
QUESTIONS INVESTIGATED: The recent emergence of arboviruses such as Chikungunya virus (CHIKV) and Zika virus (ZIKV) in Brazil has posed a threat to human health and to the country's economy. Outbreaks occur mainly in tropical areas; however, increasing number of cases have been observed in Rio Grande do Sul (RS), the Southernmost state; therefore, surveillance of these arboviruses is essential for public health measures. DESIGN: In this study, we analyzed 1276 samples from patients with clinically suspected arboviral diseases between 2014 and 2016...
September 20, 2017: Reviews in Medical Virology
https://www.readbyqxmd.com/read/28929521/safety-tolerability-and-pharmacokinetics-of-radavirsen-avi-7100-an-antisense-oligonucleotide-targeting-influenza-a-m1-m2-translation
#17
John H Beigel, Jocelyn Voell, Paula Muñoz, Parag Kumar, Kristina M Brooks, Jianbo Zhang, Patrick Iversen, Alison Heald, Michael Wong, Richard T Davey
AIMS: To assess the safety, tolerability, and pharmacokinetics (PK) of radavirsen following single ascending doses and multiple doses given as IV infusions in healthy adults. METHODS: A Phase 1 safety and pharmacokinetic (PK) study of radavirsen was performed in healthy volunteers. The study was divided into 2 parts. The first was a single-ascending dose study of 5 cohorts of 8 subjects each, randomized 6:2 to receive single intravenous doses of radavirsen ranging from 0...
September 20, 2017: British Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/28929486/migraine-and-invasive-epithelial-ovarian-cancer-risk-in-the-nurses-health-study-ii-and-the-women-s-health-study
#18
Megan S Rice, Pamela M Rist, Anke C Winter, Tobias Kurth, Shelley S Tworoger
Migraine is a common primary headache disorder, which predominantly impacts women. Recently, migraine has been hypothesized to be associated with hormonally related cancers; however the potential association between migraine and ovarian cancer has not been studied. Therefore, we evaluated the association between migraine and invasive epithelial ovarian cancer risk in two prospective cohorts, the Nurses' Health Study II (NHSII) and the Women's Health Study (WHS). Our prospective analysis included 113,124 NHSII participants aged 25-42 at study baseline as well as 33,490 participants in the WHS who were 45 years or older at study entry...
September 20, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28929415/pediatric-neurocysticercosis
#19
REVIEW
Pratibha Singhi, Arushi Gahlot Saini
Neurocysticercosis is the most common helminth infection of nervous system in humans caused by the encysted larvae of Taenia solium. It is a major cause of epilepsy in tropical areas and the most common cause of focal-onset seizures in North Indian children. Children with neurocysticercosis have pleomorphic manifestations depending on the location, number and viability of the cysts and host response. In endemic areas, neurocysticercosis should be clinically suspected in any child with recent-onset seizures, headache or focal motor deficits where there is no other suggestion of an underlying neurological disorder...
September 20, 2017: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/28929224/long-working-hours-directly-and-indirectly-via-short-sleep-duration-induce-headache-even-in-healthy-white-collar-men-cross-sectional-and-1-year-follow-up-analyses
#20
Teruo Nagaya, Minoru Hibino, Yasuaki Kondo
OBJECTIVE: Headache in employees may be linked with both overwork and sleep restriction induced by long working hours. Inter-relationships among working hours, sleep duration and headache were investigated. METHODS: Cross-sectional analyses for prevalent headache (n = 35,908) and 1-year follow-up analyses for incident headache (n = 19,788) were conducted in apparently healthy white-collar men aged 25-59 years. Headache (yes/no), working hours and sleep duration were based on self-administered questionnaire...
September 19, 2017: International Archives of Occupational and Environmental Health
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