keyword
https://read.qxmd.com/read/38503593/comparison-of-laparoscopic-common-bile-duct-exploration-plus-cholecystectomy-and-endoscopic-retrograde-cholangiopancreatography-followed-by-laparoscopic-cholecystectomy-for-elderly-patients-with-common-bile-duct-stones-and-gallbladder-stones
#21
JOURNAL ARTICLE
Po-Hsuan Wu, Min-Wei Yu, Shih-Chang Chuang, Shen-Nien Wang, Kung-Kai Kuo, Wen-Tsan Chang, Shu-Hung Chuang, Wen-Lung Su, Jian-Wei Huang, Ling-An Chen
BACKGROUND: Common bile duct (CBD) stones commonly occur in cholecystectomy cases. The management options include laparoscopic CBD exploration (LCBDE) or endoscopic retrograde cholangiopancreatography (ERCP) followed by laparoscopic cholecystectomy (LC). Although ERCP is fully developed, it has complications, and LCBDE is a proven alternative. This study aimed to evaluate the safety and efficacy of these treatments in elderly individuals aged ≥70 years. METHODS: A retrospective study between January 2015 and July 2022 included 160 elderly patients (aged ≥70 years) diagnosed with cholelithiasis and choledocholithiasis...
March 1, 2024: Journal of Gastrointestinal Surgery
https://read.qxmd.com/read/38501150/advanced-adenosquamous-carcinoma-of-the-ampulla-of-vater-treated-with-adjuvant-chemotherapy-after-pancreaticoduodenectomy
#22
JOURNAL ARTICLE
Hiroyuki Hakoda, Yoshikuni Kawaguchi, Yoichi Miyata, Junichi Togashi, Motoki Nagai, Yoshio Suzuki, Yukihiro Nomura
INTRODUCTION: Adenosquamous carcinoma (ASC) of the ampulla of Vater (AmV) is rare. The prognosis is generally worse in patients undergoing resection of ASC of the AmV than in those undergoing resection of adenocarcinoma of the AmV because the former shows early recurrence after surgery. A treatment strategy for ASC of the AmV has not been established, and the efficacy of adjuvant chemotherapy after curative resection is unclear. Given the paucity of data, we report a case of ASC of the AmV that was curatively resected and treated with adjuvant chemotherapy...
2024: Case Reports in Gastroenterology
https://read.qxmd.com/read/38499781/effect-of-anti-reflux-suture-on-gastroesophageal-reflux-symptoms-after-one-anastomosis-gastric-bypass-a-randomized-controlled-trial
#23
JOURNAL ARTICLE
Mohammad Kermansaravi, Masoumeh Shahsavan, Reza Ebrahimi, Ali Mousavimaleki, Barmak Gholizadeh, Rohollah Valizadeh, Shahab ShahabiShahmiri, Miguel A Carbajo
PURPOSE: Gastroesophageal reflux disease (GERD) is an issue after one anastomosis gastric bypass (OAGB) and modification of OAGB with adding an anti-reflux system may decrease the incidence of postoperative GERD. This study aimed to compare the efficacy of the anti-reflux mechanism to treat preoperative GERD and prevent de novo GERD. METHODS: A prospective randomized clinical trial study was conducted on patients with a body mass index of 40 and more from August 2020 to February 2022...
March 18, 2024: Surgical Endoscopy
https://read.qxmd.com/read/38494180/congenital-bilio-bronchial-fistula-in-an-adult-a-review-of-literature-and-video-demonstration-of-laparoscopic-fistula-tract-excision
#24
REVIEW
Chandrasekar Murugesan, Muniza Bai, Biju Pottakkat, Dharm Prakash Dwivedi, Hemachandren Munuswamy, Pazhanivel Mohan
This article presents a review of the literature on congenital bilio-bronchial fistula (BBF), a rare anomaly characterized by abnormal communication between the bile duct and respiratory tract. Congenital BBF often presents with bilioptysis in early neonates and infants; however, patients with no overt symptoms may occasionally present in adulthood. Our literature search in Medline from 1850 to 2023 revealed 42 reported cases of congenital BBF, primarily managed with thoracotomy and excision of the fistula tract...
March 15, 2024: Journal of minimally invasive surgery
https://read.qxmd.com/read/38492316/pleural-migration-of-biliary-stent-10-years-following-treatment-of-hepatic-hydatic-echinococcosis-a-case-report
#25
S Atri, R Elaifia, A Sebai, M Hammami, A Haddad, J M Kacem
INTRODUCTION: Echinococcosis, caused by larval stages of taeniid cestodes, primarily affects the liver and is commonly treated surgically. However, a complication post-treatment is biliary fistula, necessitating interventions like biliary stents. While stent complications are recognized, proximal migration leading to pneumonia is exceptionally rare. This case report details an unusual occurrence of biliary stent migration years after hepatic hydatid echinococcosis treatment. CASE PRESENTATION: A 42-year-old patient underwent 2014 surgery for a large hydatid cyst, resulting in a biliary fistula...
March 13, 2024: International Journal of Surgery Case Reports
https://read.qxmd.com/read/38491413/comparison-of-vonoprazan-and-proton-pump-inhibitors-for-the-treatment-of-gastric-endoscopic-submucosal-dissection-induced-ulcer-an-updated-systematic-review-and-meta-analysis
#26
JOURNAL ARTICLE
Lizhen Chen, Dalei Jiang, Doudou Hu, Xianghua Cui
BACKGROUND: Both vonoprazan and proton pump inhibitors (PPIs) are currently used to treat artificial ulcers after gastric endoscopic submucosal dissection. However, evidence-based medicine proving the efficacy of vonoprazan is still lacking. Therefore, this meta-analysis aimed to compare the efficacy of vonoprazan and PPIs for the treatment of artificial ulcers after gastric endoscopic submucosal dissection. METHODS: The PubMed, EMBASE and Cochrane Library databases were searched up to September 2023 for related randomized controlled trials (RCTs)...
March 15, 2024: BMC Gastroenterology
https://read.qxmd.com/read/38490808/components-from-curcuma-longa-turmeric-against-hepatobiliary-diseases-based-on-gut-liver-axis-pharmacotherapeutic-properties-and-potential-clinical-applications
#27
JOURNAL ARTICLE
Tianhui Gao, Shuyi Wang, Zongping Zhu, Liting Lin, Yirong Luo, Meigui Lu, Wan Liao
Turmeric is widely used worldwide, and there are many examples of its use in treating hepatobiliary diseases. The gut-liver axis is a bidirectional relationship between gut microorganisms and the liver that is closely related to the pathogenesis of hepatobiliary diseases. This review systematically summarizes the components of turmeric. It links the studies on turmeric affecting gut microorganisms to its effects on liver and biliary diseases to explain the potential mechanism of turmeric's regulation of the gut-liver axis...
March 16, 2024: American Journal of Chinese Medicine
https://read.qxmd.com/read/38487984/hepatobiliary-circulation-and-dominant-urinary-excretion-of-homogentisic-acid-in-a-mouse-model-of-alkaptonuria
#28
JOURNAL ARTICLE
B P Norman, H Sutherland, P J M Wilson, D A Rutland, A M Milan, A T Hughes, A S Davison, M Khedr, J C Jarvis, J A Gallagher, G Bou-Gharios, L R Ranganath
Altered activity of specific enzymes in phenylalanine-tyrosine (phe-tyr) metabolism results in incomplete breakdown of various metabolite substrates in this pathway. Increased biofluid concentration and tissue accumulation of the phe-tyr pathway metabolite homogentisic acid (HGA) is central to pathophysiology in the inherited disorder alkaptonuria (AKU). Accumulation of metabolites upstream of HGA, including tyrosine, occurs in patients on nitisinone, a licenced drug for AKU and hereditary tyrosinaemia type 1, which inhibits the enzyme responsible for HGA production...
March 15, 2024: Journal of Inherited Metabolic Disease
https://read.qxmd.com/read/38483785/colorectal-metastases-with-intrabiliary-growth-incidence-treatment-and-outcomes
#29
JOURNAL ARTICLE
Serena Langella, Serena Armentano, Nadia Russolillo, Andrea-Pierre Luzzi, Andrea Pierluigi Fontana, Lorenzo Daniele, Alessandro Ferrero
Intrabiliary growth (IG) is an unusual modality for colorectal metastases to spread. Relatively little is known about this condition because large series are lacking. The aim of the study was to compare the surgical and oncological outcomes of patients with or without IG. From 01/2010 to 12/2020, 999 patients underwent hepatectomy for colorectal metastases. Clinicopathological variables were retrospectively analyzed from a prospective-collected database of patients with or without IG. A propensity score matched (PSM) analysis to compare OS and DFS was performed...
March 14, 2024: Updates in Surgery
https://read.qxmd.com/read/38482476/full-depth-evaluation-of-the-bile-duct-with-a-7f-cholangioscope-and-its-possibility-for-guiding-therapeutics
#30
REVIEW
Carlos Robles-Medranda, Maria Egas-Izquierdo, Domenica Cunto, Jorge Baquerizo-Burgos, Juan Alcivar-Vasquez
BACKGROUND AND AIMS: Digital single-operator cholangioscopy (DSOC) plays a critical role in directly visualizing and treating the bile duct system. Although various cholangioscopes with different external diameters are available for DSOC, certain challenging scenarios persist in which existing scopes fail to complete a thorough evaluation of the bile ducts. To overcome these limitations, we aimed to introduce and highlight the application of a novel 7F cholangioscope. METHODS: In this review article we describe the novel 7F cholangioscope, provide its assembly and setup, and review cases in which the 7F cholangioscope was used for diagnostic and therapeutic guidance...
March 2024: VideoGIE
https://read.qxmd.com/read/38477473/diagnostic-efficacy-of-a-novel-rotating-brush-for-endoscopic-sampling-of-malignant-biliary-strictures-a-multicenter-prospective-study
#31
JOURNAL ARTICLE
Mingxing Xia, Zhenyang Shen, Haiming Zheng, Lin Yuan, Jiangfeng Hu, Yi Zhao, Dongxun Zhou, Xianghui Bai, Junjun Wang, Xiaoman Li, Weiming Dai, Mei Kang, Hui Zhou, Rong Wan, Lungen Lu, Bing Hu, Xinjian Wan, Xiaobo Cai
OBJECTIVES: Although cytologic examination of biliary stricture brushings obtained via endoscopic retrograde cholangiopancreatography (ERCP) is commonly used for diagnosing malignant biliary strictures (MBSs), it has low sensitivity. Several new brushes have capabilities that are still being debated. We have developed a novel brush working from conventional back-and-forth movement to rotation in situ (RIS) that may be more efficient for MBS sampling. We aimed to compare the MBSs detection sensitivity of our RIS brush with that of the conventional brush...
March 13, 2024: American Journal of Gastroenterology
https://read.qxmd.com/read/38475671/role-of-advanced-endoscopy-in-the-management-of-inflammatory%C3%A2-digestive-diseases-pancreas-and-biliary-tract
#32
REVIEW
Toshiharu Ueki, Toru Maruo, Yoshinori Igarashi, Akira Yamamiya, Keiichi Tominaga, Atsushi Irisawa, Hitoshi Yoshida, Terumi Kamisawa, Mamoru Takenaka, Hiroyuki Isayama
The progress of endoscopic diagnosis and treatment for inflammatory diseases of the biliary tract and pancreas have been remarkable. Endoscopic ultrasonography (EUS) and EUS-elastography are used for the diagnosis of early chronic pancreatitis and evaluation of endocrine and exocrine function in chronic pancreatitis. Notably, extracorporeal shock wave lithotripsy and electrohydraulic shock wave lithotripsy have improved the endoscopic stone removal rate in patients for whom pancreatic stone removal is difficult...
March 12, 2024: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://read.qxmd.com/read/38469173/percutaneous-microwave-ablation-for-early-stage-intrahepatic-cholangiocarcinoma-a-single-institutional-cohort
#33
JOURNAL ARTICLE
Sophia Humphrey, Jack Bailey Newcomer, Driss Raissi, Gaby Gabriel
OBJECTIVES: Cholangiocarcinoma (CCA) is the second-most common primary hepatic malignancy with an increasing incidence over the past two decades. CCA arises from the epithelial cells lining the bile ducts and can be classified as intrahepatic, perihilar, or distal based on the site of origin in the biliary tree. Surgical resection is the definitive curative therapy for early-stage intrahepatic CCA; however, only a minority of patients may be ideal surgical candidates. Percutaneous microwave ablation (MWA) is a minimally invasive procedure widely used for hepatocellular carcinoma and colorectal cancer metastases to the liver...
2024: Journal of Clinical Imaging Science
https://read.qxmd.com/read/38468561/sorafenib-vs-lenvatinib-in-advanced-hepatocellular-carcinoma-after-atezolizumab-bevacizumab-failure-a-real-world-study
#34
JOURNAL ARTICLE
Young Eun Chon, Dong Yun Kim, Mina Kim, Beom Kyung Kim, Seung Up Kim, Jun Yong Park, Sang Hoon Ahn, Yeonjung Ha, Joo Ho Lee, Kwan Sik Lee, Beodeul Kang, Jung Sun Kim, Hong Jae Chon, Do Young Kim
BACKGROUND: Atezolizumab plus bevacizumab (ATE+BEV) therapy has become the recommended first-line therapy for patients with unresectable hepatocellular carcinoma (HCC) because of favorable treatment responses. However, there is a lack of data on sequential regimens after ATE+BEV treatment failure. We aimed to investigate the clinical outcomes of patients with advanced HCC who received subsequent systemic therapy for disease progression after ATE+BEV. METHODS: This multicenter, retrospective study included patients who started second-line systemic treatment with sorafenib or lenvatinib after HCC progressed on ATE+BEV between August 2019 and December 2022...
March 12, 2024: Clinical and Molecular Hepatology
https://read.qxmd.com/read/38463545/efficacy-and-safety-of-conversion-surgery-for-advanced-hepatocellular-carcinoma-after-hepatic-arterial-infusion-chemotherapy
#35
JOURNAL ARTICLE
Wenxuan Li, Zhikai Zheng, Jiongliang Wang, Tianqing Wu, Juncheng Wang, Yangxun Pan, Jinbin Chen, Dandan Hu, Li Xu, Yaojun Zhang, Minshan Chen, Zhongguo Zhou
PURPOSE: The aim of this study was to investigate the efficacy and safety of conversion surgery for advanced hepatocellular carcinoma (HCC) after hepatic arterial infusion chemotherapy (HAIC). PATIENTS AND METHODS: Data from 172 HCC patients treated at Sun Yat-sen University Cancer Center between January 2016 and June 2021 with effective assessment of HAIC treatment response were retrospectively analyzed. Clinical pathological data, treatment process, survival, and occurrence of adverse events were recorded...
2024: Journal of Hepatocellular Carcinoma
https://read.qxmd.com/read/38463464/timing-of-cholecystectomy-in-severe-pancreatitis-chispa-study-protocol-for-a-randomized-controlled-trial
#36
JOURNAL ARTICLE
Camilo Ramírez-Giraldo, Danny Conde Monroy, José Alejandro Daza Vergara, Andrés Isaza-Restrepo, Isabella Van-Londoño, Luisa Trujillo-Guerrero
Acute pancreatitis is the recurrent reason for gastrointestinal admission in a clinical urgent setting, it happens secondary to a wide array of pathologies out of which biliary disease stands as one of the most frequent causes for its presentation. Approximately 20% of pancreatitis are of moderate or severe severity. Currently, there is not a clear recommendation on timing for cholecystectomy, either early or delayed. CHISPA is a randomized controlled, parallel-group, superior clinical trial. An intention-to-treat analysis will be performed...
2024: BMJ surgery, interventions, & health technologies
https://read.qxmd.com/read/38454160/ursodeoxycholic-acid-ameliorates-erectile-dysfunction-and-corporal-fibrosis-in-diabetic-rats-by-inhibiting-the-tgf-%C3%AE-1-smad2-pathway
#37
JOURNAL ARTICLE
Irem Cavusoglu Nalbantoglu, Serhat Sevgi, Gokcen Kerimoglu, Mine Kadıoglu Duman, Nuri Ihsan Kalyoncu
Corporal tissue fibrosis is critical in diabetes-associated erectile dysfunction. Transforming growth factor-β1/Small mothers against decapentaplegic-2 (TGF-β1/Smad2) contributes to the induction of fibrosis in corporal tissue. Smad7 is accepted as a general negative regulator of Smad signaling, although its role in corporal fibrosis is unknown. Ursodeoxycholic acid (UDCA) is a hydrophilic bile acid used for biliary and liver related disorders and has antifibrotic effects in the liver. This study investigated the effects of UDCA on diabetic erectile dysfunction...
March 7, 2024: International Journal of Impotence Research
https://read.qxmd.com/read/38450573/using-endoscopic-radial-incision-and-cutting-combined-with-endoscopic-retrograde-cholangiopancreatography-to-treat-biliary-enteric-anastomotic-stricture-and-stones
#38
JOURNAL ARTICLE
Li Wang, Wei-Feng Chen, Ping-Hong Zhou
No abstract text is available yet for this article.
March 7, 2024: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://read.qxmd.com/read/38450271/a-choledochal-cyst-type-iva-in-a-child-treated-with-roux-en-y-hepaticojejunostomy
#39
JOURNAL ARTICLE
Sulaiman Yusuf, Alivia R Nuriyanto, Nurul Nadia, Muntadhar Muntadhar, Yumna Muzakkir, Nurhayani D Susanti, Zain Al-Shather, Fenny Harrika
A choledochal cyst is a bile duct anomaly that disrupts the transportation of bile from the liver to the gallbladder and small intestine. Choledochal cysts are rare, occurring in approximately one out of every 100,000 to 150,000 children in Western countries, with a girls-to-boys ratio of 4:1. Immediate surgery to excise the cyst and construct a biliary-enteric continuity is necessary to treat this condition. This case-report aimed to present a child with choledochal cyst type IVa who underwent a Roux-en-Y hepaticojejunostomy...
August 2023: Narra J
https://read.qxmd.com/read/38449489/duodenal-stump-fistula-managed-with-percutaneous-drainage-percutaneous-transcholecystic-biliary-diversion-and-transduodenal-glue-embolization-a-case-report
#40
Gernot Rott, Frieder Boecker, Simon Schimmack
Duodenal stump insufficiency is an infrequent but potentially devastating complication of upper gastrointestinal surgery. In the era of image-guided interventions, duodenal stump insufficiency is usually treated rather conservatively or with percutaneous interventions than with surgery. Herein, we present a case of a postsurgical duodenal stump fistula successfully treated in a step-by-step manner with percutaneous drainage of a periduodenal abscess-fistula complex, percutaneous transcholecystic biliary drainage for partial biliary diversion and percutaneous transcatheter fistula embolization via the duodenum with n-butyl-cyanoacrylate...
May 2024: Radiology Case Reports
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