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phototherapy hypocalcemia

Afshin Safaei Asl, Marjaneh Zarkeshl, Abtin Heidarzadeh, Shohreh Maleknejad, Kaveh Hagikhani
Phototherapy is the most common, most effective, and least dangerous treatment method for neonatal hyperbilirubinemia and is the treatment of the first choice for neonatal icterus. Hypocalcemia is one of the lesser-known complications of phototherapy. Some studies have shown a relationship between increased urinary calcium excretion and phototherapy-induced hypocalcemia. We aimed to assess the effect of phototherapy on urinary calcium excretion in term neonates. This before-after study was performed on 80 term neonates having hyper- bilirubinemia referred to the 17(th) Shahrivar Hospital, Rasht, Guilan Province, Northern Iran, over a one-year period from May 2013 to May 2014...
May 2016: Saudi Journal of Kidney Diseases and Transplantation
Xiao-Rui Zhang, Chao-Mei Zeng, Jie Liu
OBJECTIVE: To study the effect and safety of intensive phototherapy in the treatment of neonatal hyperbilirubinemia. METHODS: A total of 144 neonates with neonatal hyperbilirubinemia were randomly and prospectively divided into intensive phototherapy group and conventional phototherapy group, with 72 neonates in each group. The therapeutic effect and incidence of complications were compared between the two groups. RESULTS: Within 12 hours after phototherapy, the total serum bilirubin level in the intensive phototherapy group was significantly lower than in the conventional phototherapy group (P<0...
March 2016: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
Abdolmajid Nazemi Gheshmi, Salma Naderi, Elham Homayrani, Batool Safari
INTRODUCTION: Hyperbilirubinemia is one of the most common problems in newborns, and it is reported in about 60% of infants. Phototherapy is used extensively to treat these patients, and hypocalcemia is one important side effect of the phototherapy. The aim of this study was to determine the prevalence of hypocalcemia after phototherapy in full-term newborns that underwent phototherapy in Koodakan Hospital in Bandar Abbas in 2013. METHODS: This cross-sectional study was conducted on 100 neonates admitted to Koodakan Hospital in Bandar Abbas...
October 2015: Electronic Physician
Marzieh Kargar, Zahra Jamshidi, Nooshin Beheshtipour, Narjes Pishva, Maryam Jamali
BACKGROUND: Although phototherapy has been used for more than 60 years it has some complications. The light waves produced from phototherapy reduce melatonin concentration in newborns with subsequent hypocalcemia. We aimed to assess the effect of head covering on calcium and magnesium levels in full term newborns during phototherapy. METHODS: In this randomized controlled trial, 72 full-term icterus newborns weighing >2500 gr with indirect hyperbillirubinemia who received phototherapy at the phototherapy ward of Moslemin Hospital, Shiraz, southwest Iran, during March to September 2010 were recruited and divided randomly into two groups...
April 2014: International Journal of Community Based Nursing and Midwifery
Paymaneh Alizadeh-Taheri, Negar Sajjadian, Bahareh Eivazzadeh
No abstract text is available yet for this article.
December 2013: Iranian Journal of Pediatrics
Karin Amrein, Harald C Worm, Gernot Schilcher, Peter Krisper, Harald Dobnig
CONTEXT: Intestinal mucosa seems to be responsive not only to circulating calcitriol but also to serum 25-hydroxyvitamin D concentrations. OBJECTIVE: We report a complex patient with chronic kidney disease who presented with symptomatic hypocalcemia (ionized calcium, 0.77 mmol/liter) despite regular calcitriol and calcium supplementation. METHODS: Case history, laboratory evaluation, and bone biopsies are discussed. RESULTS: Only vigorous treatment with im cholecalciferol led to a significant improvement of serum calcium, a decrease in PTH levels, and histological improvement of osteomalacic bone disease...
June 2012: Journal of Clinical Endocrinology and Metabolism
(no author information available yet)
The National Neonatal Perinatal Database (NNPD) network is a collaborative group of leading neonatal units in India involved in the prospective collection of morbidity and mortality data on uniform protocols. The present article reports the morbidity and mortality profile of outborn neonates in the year 2000. Ten centers provided data on outborn neonates. The data were analysed at the nodal center using Epi-Info statistical software version 6 and Excel 97. A total of 3831 neonates were admitted at the participating institutions...
June 2004: Journal of Tropical Pediatrics
O Nakade, H Koyama, H Ariji, A Yajima, T Kaku
The pineal secretory product melatonin reportedly regulates release of growth hormone in humans and prevents phototherapy-induced hypocalcemia in newborn rats, suggesting that melatonin affects bone metabolism. Little is known about the effects of melatonin on bone in vitro or in vivo. The present study was undertaken to examine whether melatonin acts directly on normal human bone cells (HOB-M cells) and human osteoblastic cell line (SV-HFO cells) to affect osteogenic action in vitro. The effect of melatonin on bone cell proliferation was determined using the 2,3-bis[2-methoxy-4-nitro-5-sulfophenyl]-2H-tetrazolium-5-carbo xanilide (XTT) assay after a 24 hr incubation with melatonin...
September 1999: Journal of Pineal Research
N Dozio, A Beretta, M Castiglioni, S Rosa, M Scavini, C Belloni, A Poloniato
OBJECTIVE: To evaluate whether the presence of insulin antibodies (IAs) may preclude the optimization of metabolic control during pregnancy and affect outcome in women with IDDM. RESEARCH DESIGN AND METHODS: IAs were measured by radiobinding assay in 44 women with IDDM referred to the Diabetes and Pregnancy Outpatients' Clinic during 46 pregnancies. Age, duration of IDDM, metabolic control (HbA1c, mean pre- and postprandial capillary blood glucose, frequency of hypo- or hyperglycemia), insulin requirement at 1st and 3rd trimester of pregnancy, BM1, and weight gain were recorded...
September 1996: Diabetes Care
H Sethi, A Saili, A K Dutta
Sixty neonates with hyperbilirubinemia were included in the study. There were 20 preterm (Group A) and 20 full term (Group B) neonates. Ten neonates from each group formed the control group. The study group neonates were managed with phototherapy while the control group neonates were not subjected to phototherapy. Serum calcium levels of the two groups were studied. Ninety per cent preterm neonates and seventy-five per cent full term neonates developed hypocalcemia after being subjected to phototherapy. There was a highly significant fall in the total as well as ionized calcium levels in the study group in contrast to the control group...
December 1993: Indian Pediatrics
N Doshi, B Klionsky, T Fujikura, H MacDonald
The recent increase in the occurrence of pulmonary yellow hyaline membranes correlates with improved therapy for premature infants with the respiratory distress syndrome and with their prolonged survival. We compared the clinicopathologic features in 54 cases with pulmonary yellow hyaline membranes with those in 56 cases with conventional hyaline membranes seen during the same interval at Magee-Womens Hospital. Kernicterus, intraventricular hemorrhage, intrahepatic bile stasis, pulmonary hemorrhages, and disseminated intravascular coagulation were significantly frequent in the yellow hyaline membrane group...
September 1980: Human Pathology
D O Hakanson, W H Bergstrom
When young rats are exposed to white fluorescent light the concentration of calcium in their serum decreases. This effect is prevented by shielding the occiput, by inhibiting corticosterone synthesis, and by exogenous melatonin. Furthermore, the expected hypocalcemic response to cortisol injection is prevented by melatonin. Light-induced hypocalcemia may result from increased calcium uptake by bone when the blocking effect of melatonin decreases after pineal inhibition by transcranial illumination.
November 13, 1981: Science
G R Gutcher, G B Odell
No abstract text is available yet for this article.
February 1983: Photochemistry and Photobiology
E Zecca, C Romagnoli, G Tortorolo
Phototherapy causes a higher incidence of hypocalcemia in preterm infants by still unknown pathogenetic mechanism. The authors studied 100 preterm newborns in order to verify whether Calcifediolo (25-OH-D3) could be useful to prevent the phototherapy-induced hypocalcemia. Results obtained show that Calcifediolo is not able, anyway, to lower the increase of the phototherapy-induced hypocalcemia in preterm infants. Vit D is therefore unlikely to play any important role in the patogenesis of phototherapy-induced hypocalcemia...
September 1983: La Pediatria Medica e Chirurgica: Medical and Surgical Pediatrics
C Romagnoli, G Polidori, L Cataldi, G Tortorolo, G Segni
No abstract text is available yet for this article.
May 1979: Journal of Pediatrics
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