keyword
MENU ▼
Read by QxMD icon Read
search

Oral lichen planus

keyword
https://www.readbyqxmd.com/read/28079787/oral-and-vulvo-vaginal-lichenoid-reactions-due-to-mitotane-lysodren-a-case-report
#1
Arthur Schmouchkovitch, Héloïse Herry, Philippe Thuillier, Véronique Kerlan, Camille Fleuret, Guy Le Toux, Sylvie Boisramé
BACKGROUND: The purpose of pharmacovigilance (drug safety) is collection, detection, assessment, monitoring, and prevention of adverse effects with pharmaceutical products. It is meant to identify, characterize, prevent, or minimize actual or potential risks relating to medicinal products. To prevent these adverse effects and improve our practice, health professionals have a duty to report side effects to assess this risk and evaluate the benefit/risk requirements. Mitotane (Lysodren) is used for treating adrenocortical carcinoma...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28077900/prevalence-of-oral-lichen-planus-in-diabetes-mellitus-a-meta-analysis-study
#2
Hamid Reza Mozaffari, Roohollah Sharifi, Masoud Sadeghi
BACKGROUND: Oral lichen planus (OLP) is associated with various other systemic conditions such as hypertension, diabetes mellitus (DM). This study evaluated the prevalence of OLP in DM patients compared with non-diabetic control subjects in a meta-analysis study. METHODS: In this study from January 1973 to August 2016, we searched the studies in Web of Science, Medline/PubMed, Scopus, Science direct, SID (Scientific Information Database), Cochrane and Embase databases...
December 2016: Acta Informatica Medica: AIM
https://www.readbyqxmd.com/read/28076499/association-between-the-clinical-severity-of-oral-lichen-planus-and-anti-tpo-level-in-thyroid-patients
#3
Milad Alikhani, Parichehr Ghalaiani, Elham Askariyan, Zahra Ahmadi Khunsaraki, Atefeh Tavangar, Aliasghar Naderi
This study considered a possible relationship between the severity of oral lichen planus (OLP), serum anti-TPO autoantibodies (TPOAb) titer and thyroid disease in OLP patients. Forty-six OLP patients with positive TPOAb results (> 35 IU/ml) who had also been diagnosed with thyroid disease were included in the study group. The control group consisted of 46OLP patients with no thyroid disease. The study and control groups (92) were divided to two subgroups of erosive OLP (EOLP) and non-erosive OLP (NEOLP)...
January 5, 2017: Brazilian Oral Research
https://www.readbyqxmd.com/read/28065765/genome-wide-association-study-identifies-risk-variants-for-lichen-planus-in-patients-with-hepatitis-c-virus-infection
#4
Yumiko Nagao, Nao Nishida, Licht Toyo-Oka, Atsushi Kawaguchi, Antonio Amoroso, Marco Carrozzo, Michio Sata, Masashi Mizokami, Katsushi Tokunaga, Yasuhito Tanaka
BACKGROUND & AIMS: There is a close relationship between hepatitis C virus (HCV) infection and lichen planus, a chronic inflammatory muco-cutaneous disease. We performed a genome-wide association study (GWAS) to identify genetic variants associated with HCV-related lichen planus. METHODS: We conducted a GWAS of 261 patients with HCV infection treated at a tertiary medical center in Japan from October 2007 through January 2013; 71 had lichen planus and 190 had normal oral mucosa...
January 5, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28060366/oral-lichenoid-lesions-distinguishing-the-benign-from-the-deadly
#5
Susan Müller
Oral lichen planus is a chronic inflammatory disease of unknown etiology or pathogenesis with varied disease severity that waxes and wanes over a long period of time. Although a common oral mucosal disease, accurate diagnosis is often challenging due to the overlapping clinical and histopathological features of oral lichen planus and other mucosal diseases. Other immune-mediated mucocutaneous diseases can exhibit lichenoid features including mucous membrane pemphigoid, chronic graft-versus-host disease, and discoid lupus erythematosus...
January 2017: Modern Pathology: An Official Journal of the United States and Canadian Academy of Pathology, Inc
https://www.readbyqxmd.com/read/28055124/interventions-for-the-management-of-oral-lichen-planus-a-review-of-the-conventional-and-novel-therapies
#6
REVIEW
Shikha Gupta, Sujoy Ghosh, Sunita Gupta
OBJECTIVE: This narrative review focuses on the rationale & role of conventional and newer therapies in the management of Oral lichen planus with emphasis on randomized controlled trials reported over 2 decades. MATERIALS AND METHODS: Literature search was conducted to identify randomized controlled trials for management of OLP from 1/1/1995 to 31/12/2015; Medline, and Cochrane databases complemented with manual search was used. Primary outcome as resolution of pain was evaluated with analysis of clinical resolution of erythema and ulceration as secondary outcome...
January 5, 2017: Oral Diseases
https://www.readbyqxmd.com/read/28045749/histologic-assessment-of-lichenoid-dermatitis-observed-in-patients-with-advanced-malignancies-on-antiprogramed-cell-death-1-anti-pd-1-therapy-with-or-without-ipilimumab
#7
Shaun Chou, Shelley Ji Eun Hwang, Giuliana Carlos, Deepal Wakade, Pablo Fernandez-Penas
Lichenoid drug reaction is a common adverse reaction in patients taking immune-modulatory agents such as antiprogramed cell death (PD-1) and cytotoxic T lymphocyte antigen-4 agents. The authors describe the clinical and histologic features of lichenoid drug reaction in 20 biopsies from 15 patients on anti-PD-1 agents and 9 biopsies from 7 patients on anti-PD-1 plus ipilimumab therapy. Clinically, all except 2 patients presented with discrete, violaceous exanthematous papules to plaques. The lichenoid inflammation in the majority (18 of 29 biopsies) was florid although histology was quite heterogeneous...
January 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28042431/vulvovaginal-gingival-lichen-planus-report-of-two-cases-and-review-of-literature
#8
REVIEW
A Lucchese, A Dolci, G Minervini, C Salerno, D DI Stasio, G Minervini, L Laino, F Silvestre, R Serpico
PURPOSE: Oral Lichen Planus (OLP) is a chronic inflammatory disease of skin and mucous membranes. Approximately 20% of women with oral lichen planus develops lesions in the genital mucosa. In 1982, Pelisse described a special form of lichen planus (LP), which consists of a triad of symptoms: vulval, vaginal and gingival (VVG)-LP lesions. Aim of the present report is to report two new cases and review the international literature. MATERIAL AND METHODS: Two cases of VVG-LP are reported and a review of recent literature is performed...
April 2016: Oral & Implantology
https://www.readbyqxmd.com/read/28029732/the-efficacy-of-aloe-vera-in-management-of-oral-lichen-planus-a-systematic-review-and-meta-analysis
#9
REVIEW
Shereen Ali, Walaa Wahbi
OBJECTIVES: The main objective of oral lichen planus management is to control symptomatic outbreaks via eliminating lesions and alleviating symptoms. Corticosteroids; calcineurin inhibitors and most of the available modalities are associated with adverse effects which may limit their use. The aim of this review was to assess the effect of Aloe Vera on pain alleviation and/or clinical improvement in patients with symptomatic oral lichen planus. METHODS: MEDLINE-PubMed; CENTRAL and LILACS were searched in May, 2016 to identify all clinical trials evaluating Aloe Vera versus placebo or corticosteroids for treatment of oral lichen planus...
December 28, 2016: Oral Diseases
https://www.readbyqxmd.com/read/28028908/allelic-loss-in-amalgam-associated-oral-lichenoid-lesions-compared-to-oral-lichen-planus-and-mucosa
#10
Leonardo Nogueira Rodrigues, Sílvia Ferreira Sousa, Raissa Cristina Costa Silva, Mauro Henrique Guimarães Abreu, Fábio Ramôa Pires, Ricardo Alves Mesquita, Luciana Bastos-Rodrigues, Luiz De Marco, Carolina Cavaliéri Gomes, Ricardo Santiago Gomez, Vanessa Fátima Bernardes
BACKGROUND: The amalgam-associated oral lichenoid lesion (AAOLL) shows clinical and histopathological features similar to oral lichen planus (OLP). Molecular researches to improve knowledge of pathogenesis and clinical behavior of AAOLL are still scarce. OBJECTIVE: We investigated for the first time the use of LOH as a molecular approach for genetic characterization of AAOLL in comparison with OLP and evaluated the cell proliferation index. MATERIALS AND METHODS: The sample comprised nine AAOLLs, 10 OLPs and eight NOMs matched by patients' gender and age...
December 27, 2016: Oral Diseases
https://www.readbyqxmd.com/read/28000306/filaggrin-gene-mutations-and-the-distribution-of-filaggrin-in-oral-mucosa-of-patients-with-oral-lichen-planus-and-healthy-controls
#11
K R Larsen, J D Johansen, J Reibel, C Zachariae, K Rosing, A M L Pedersen
BACKGROUND: Lichen planus (LP) is a chronic inflammatory disease of unknown etiology affecting the skin and oral mucosa. Oral lichenoid lesions (OLL), like oral contact reactions, may resemble oral lichen planus (OLP) both clinically and histopathologically. As OLP and OLL are hyperkeratotic diseases and filaggrin is essential to keratinization the distribution of filaggrin may be altered in these lesions. OBJECTIVES: To investigate if patients with OLP/OLL have 1) altered distribution of filaggrin in the oral mucosa, 2) a higher incidence of mutations in the filaggrin gene (FLG) and 3) active dermatoses, apart from cutaneous LP, than healthy controls; and 4) patients with OLP/OLL and a defect in the FLG have more widespread oral lesions and report more symptoms than OLP/OLL patients without a concomitant defect in the FLG...
December 21, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/27990397/unilateral-zosteriform-lichen-planus-involving-multiple-noncontiguous-dermatomes-with-oral-involvement
#12
Nidhi Jivani, Rahulkrishna S Kota, Pragya A Nair
No abstract text is available yet for this article.
November 2016: Indian Dermatology Online Journal
https://www.readbyqxmd.com/read/27982545/oral-lichen-planus-therapy-and-phenotype
#13
Bruno Loré, Rosita Saraceno, Giulio Poladas, Monika Fida, Charbel Khoury, Claudio Arcuri, Roberto Magnato
BACKGROUND: Lichen planus (LP) is a mucocutaneous disease of chronic inflammatory nature. Although many therapeutic options are available, none are curative. The aim of this article was to describe a therapeutic algorithm that take into consideration the clinical futures of oral LP (OLP). METHODS: Patients affected by symptomatic OLP were enrolled into three groups to receive cyclosporine mouthwash, retinoic acid lotion 0.05%, and autologous platelet- rich plasma (PRP) gel in the treatment of reticular, plaque-like, and erosive-type respectively...
December 16, 2016: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/27978911/-histopathological-analysis-of-oral-lichen-planus-with-malignant-transformation
#14
Y Gao, H Y Luo
Objective: To estimate the histological features of oral lichen planus (OLP) which underwent malignant transformation and discuss the current problems in OLP pathological diagnosis. Methods: Using the modified WHO OLP criteria (2003), reevaluated the pathological changes of cases diagnosed initially as OLP and transformed into squamous cell carcinomas indicated by subsequent biopsies. Results: Among 3 721 cases of OLP clinically and pathologically diagnosed during 1984 and 2015, there were 19 cases (0.51%) having underwent malignant transformation...
December 9, 2016: Zhonghua Kou Qiang Yi Xue za Zhi, Zhonghua Kouqiang Yixue Zazhi, Chinese Journal of Stomatology
https://www.readbyqxmd.com/read/27957272/the-effect-of-diode-laser-and-topical-steroid-on-serum-level-of-tnf-alpha-in-oral-lichen-planus-patients
#15
Nagwa-Abdelhamid Othman, Olfat-Gamil Shaker, Hanaa-Mohamed Elshenawy, Wessam Abd-Elmoniem, Amany-Mohy Eldin, Mariam-Yehia Fakhr
BACKGROUND: Oral lichen planus (OLP) is a common chronic inflammatory mucosal disease with a multifactorial etiology. It is a T-cell mediated autoimmune disease in which the cytotoxic CD8+T cells trigger apoptosis of the basal cells of oral epithelium. Various treatment regimens have been employed for management of symptomatic OLP. This study was carried out to evaluate the effect of topical steroids as well as laser on the clinical signs and symptoms detected by reticular, atrophic, erosive score (RAE score) and tumor necrosis factor- α (TNF-α) level in the serum of patients with symptomatic OLP...
December 2016: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/27939087/-precancerous-lesions-of-the-buccal-epithelium
#16
C Renaud-Vilmer, B Cavelier-Balloy
Squamous cell carcinomas of the oral cavity and lips consistently have a high incidence (they constitute the fifth most common form of cancer in France) and carry a heavy prognosis, particularly if diagnosed late. According to different studies, between 10 and 80% of such carcinomas occur in a pre-existing or precancerous lesion. The World Health Organisation (WHO) recommends the use of two terms for such lesions: precursor lesions, i.e. histological lesions associated with intraepithelial neoplasia (IEN) and verrucous hyperplasia (VH), frequently resulting clinically in leukoplakia or erythroplakia; "at risk" lesions, which include lichen planus, submucosal oral fibrosis and certain forms of genodermatosis...
December 6, 2016: Annales de Dermatologie et de Vénéréologie
https://www.readbyqxmd.com/read/27920651/use-of-direct-acting-antivirals-for-the-treatment-of-hepatitis-c-virus-associated-oral-lichen-planus-a-case-report
#17
Kenji Misaka, Takashi Kishimoto, Yuji Kawahigashi, Michio Sata, Yumiko Nagao
Hepatitis C virus (HCV) is frequently associated with various extrahepatic manifestations such as autoimmune features and immune complex deposit diseases. Oral lichen planus (OLP) is one of the representative extrahepatic manifestations of HCV infection. Direct-acting antivirals (DAA) are highly effective and safe for the eradication of HCV. However, there is a lack of information regarding the association between HCV-associated OLP and interferon (IFN)-free DAA therapy. Herein, we present the case of a 60-year-old female who was diagnosed with OLP during routine periodontal treatment by a dentist...
September 2016: Case Reports in Gastroenterology
https://www.readbyqxmd.com/read/27917729/efficacy-of-steroidal-vs-non-steroidal-agents-in-oral-lichen-planus-a-randomised-open-label-study
#18
A R Singh, A Rai, M Aftab, S Jain, M Singh
OBJECTIVE: This study compared the therapeutic efficacy of steroidal and non-steroidal agents for treating oral lichen planus. METHODS: Forty patients with clinical and/or histologically proven oral lichen planus were randomly placed into four groups and treated with topical triamcinolone, oral dapsone, topical tacrolimus or topical retinoid for three months. Pre- and post-treatment symptoms and signs were scored for each patient. RESULTS: Patients in all treatment groups showed significant clinical improvement after three months (p 0...
January 2017: Journal of Laryngology and Otology
https://www.readbyqxmd.com/read/27916273/identification-of-agnors-and-cytopathological-changes-in-oral-lichen-planus-lesions
#19
Stefânia Jeronimo Ferreira, Maria Ângela Naval Machado, Antônio Adilson Soares de Lima, Aline Cristina Batista Rodrigues Johann, Ana Maria Trindade Grégio, Luciana Reis Azevedo-Alanis
OBJECTIVE: To evaluate cytopathological changes in epithelial cells of the oral mucosa of patients with oral lichen planus (OLP) compared with patients without OLP. SUBJECTS AND METHODS: Swabs were collected from the oral mucosa of 20 patients with OLP (case group) and 20 patients without OLP (control group) using liquid-based cytology. After Papanicolaou staining, the smears were characterized based on Papanicolaou classification and degree of maturation. Nuclear area (NA) measurements, cytoplasmic area (CA) measurements, and the NA/CA ratio were determined from 50 epithelial cells per slide...
January 2017: Acta Histochemica
https://www.readbyqxmd.com/read/27913255/using-the-bitola-system-to-identify-candidate-molecules-in-the-interaction-between-oral-lichen-planus-and-depression
#20
Yuanbo Zhan, Shuang Zhou, Ying Li, Sen Mu, Ruijie Zhang, Xuejing Song, Feng Lin, Ruimin Zhang, Bin Zhang
Exacerbations of oral lichen planus (OLP) have been linked to the periods of psychological stress, anxiety and depression. The specific mechanism of the interaction is unclear. The aim of this study was to explore the candidate genes or molecules that play important roles in the interaction between OLP and depression. The BITOLA system was used to search all intermediate concepts relevant to the "Gene or Gene Product" for OLP and depression, and the gene expression data and tissue-specific gene data along with manual checking were then employed to filter the intermediate concepts...
November 29, 2016: Behavioural Brain Research
keyword
keyword
55983
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"