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https://www.readbyqxmd.com/read/29766126/factor-viia-administration-in-traumatic-brain-injury-an-aast-mitc-propensity-score-analysis
#1
Sarah Lombardo, D Millar, Gregory J Jurkovich, Raul Coimbra, Ram Nirula
Background: Recombinant factor VIIa (rFVIIa) has been used off-label as an adjunct in the reversal of warfarin therapy and management of hemorrhage after trauma. Only a handful of these reports are rigorous studies, from which results regarding safety and effectiveness have been mixed. There remains no clear consensus as to the role of rFVIIa in traumatic brain injury (TBI). Methods: Eleven level 1 trauma centers provided clinical data and head CT scans of patients with a Glasgow Coma Scale (GCS) score of ≤13 and radiographic evidence of TBI...
2018: Trauma surgery & acute care open
https://www.readbyqxmd.com/read/29764720/altered-somatosensory-processing-in-parkinson-s-disease-and-modulation-by-dopaminergic-medications
#2
Aimee J Nelson, Tasnuva Hoque, Carolyn Gunraj, Robert Chen
BACKGROUND: Somatosensory abnormalities contribute to the pathophysiology of Parkinson's disease (PD). The goal of this study was to identify abnormalities in the tactile-evoked activation of the somatosensory and motor cortices in PD, and in a sensorimotor circuit that traverses both of these cortical loci. The second goal was to investigate the impact of dopaminergic medication on these measures. METHODS: Individuals with PD (n = 10, age 61 ± 8 years) and aged-matched controls (n = 11, age 52...
May 7, 2018: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/29761877/diagnostic-accuracy-of-new-and-old-cognitive-screening-tools-for-hiv-associated-neurocognitive-disorders
#3
M Trunfio, D Vai, C Montrucchio, C Alcantarini, A Livelli, M C Tettoni, G Orofino, S Audagnotto, D Imperiale, S Bonora, G Di Perri, A Calcagno
OBJECTIVES: Considering the similarities between HIV-associated neurocognitive disorders (HAND) and neurodegenerative dementias and the frequency of executive dysfunctions among HIV-positive patients, we evaluated the accuracy of the Frontal Assessment Battery and Clock-Drawing Test together with the Three Questions Test and International HIV Dementia Scale to screen for HAND. METHODS: A cross-sectional monocentric study was conducted from 2010 to 2017. The index tests were represented by the four screening tools; the reference standard was represented by a comprehensive neurocognitive battery used to investigate 10 cognitive domains...
May 15, 2018: HIV Medicine
https://www.readbyqxmd.com/read/29756458/evaluation-of-the-effects-of-adding-vibrotactile-feedback-to-myoelectric-prosthesis-users-on-performance-and-visual-attention-in-a-dual-task-paradigm
#4
Eitan Raveh, Jason Friedman, Sigal Portnoy
OBJECTIVE: To evaluate the effects of adding vibrotactile feedback to myoelectric prosthesis users on the performance time and visual attention in a dual-task paradigm. DESIGN: A repeated-measures design with a counterbalanced order of two conditions. SETTING: Laboratory setting. SUBJECTS: Transradial amputees using a myoelectric prosthesis with normal or corrected eyesight ( N = 12, median age = 65 ± 13 years)...
May 1, 2018: Clinical Rehabilitation
https://www.readbyqxmd.com/read/29755152/eco-evolutionary-processes-generating-diversity-among-bottlenose-dolphin-tursiops-truncatus-populations-off-baja-california-mexico
#5
Iris Segura-García, Liliana Rojo-Arreola, Axayácatl Rocha-Olivares, Gisela Heckel, Juan Pablo Gallo-Reynoso, Rus Hoelzel
For highly mobile species that nevertheless show fine-scale patterns of population genetic structure, the relevant evolutionary mechanisms determining structure remain poorly understood. The bottlenose dolphin ( Tursiops truncatus ) is one such species, exhibiting complex patterns of genetic structure associated with local habitat dependence in various geographic regions. Here we studied bottlenose dolphin populations in the Gulf of California and Pacific Ocean off Baja California where habitat is highly structured to test associations between ecology, habitat dependence and genetic differentiation...
2018: Evolutionary Biology
https://www.readbyqxmd.com/read/29753276/impaction-of-swallowed-dentures-in-the-sigmoid-colon-requiring-sigmoid-colectomy
#6
Michael Flanagan, Cillian Clancy, Micheal G O Riordain
INTRODUCTION: Foreign body (FB) ingestion results in perforation in 1% of cases and is associated with significant morbidity and rarely mortality. Clinical presentation is variable and can present a diagnostic challenge. We report our experience and management of a patient with a delayed presentation of a sigmoid colon foreign body as a result of ingestion of a dental plate. PRESENTATION OF CASE: A 67 year old female attended the colorectal outpatient clinic following an incidental finding of a sigmoid mass on computed tomography (CT) abdomen...
May 7, 2018: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29751662/data-gathering-and-energy-transfer-dilemma-in-uav-assisted-flying-access-network-for-iot
#7
Sara Arabi, Essaid Sabir, Halima Elbiaze, Mohamed Sadik
Recently, Unmanned Aerial Vehicles (UAVs) have emerged as an alternative solution to assist wireless networks, thanks to numerous advantages they offer in comparison to terrestrial fixed base stations. For instance, a UAV can be used to embed a flying base station providing an on-demand nomadic access to network services. A UAV can also be used to wirelessly recharge out-of-battery ground devices. In this paper, we aim to deal with both data collection and recharging depleted ground Internet-of-Things (IoT) devices through a UAV station used as a flying base station...
May 11, 2018: Sensors
https://www.readbyqxmd.com/read/29741471/effect-of-object-and-task-properties-on-bimanual-transport
#8
Yuzuko C Nakamura, Carol A O'Sullivan, Nancy S Pollard
The use of both hands simultaneously when manipulating objects is fairly commonplace, but it is not known what factors encourage people to use two hands as opposed to one during simple tasks such as transport. In particular, we are interested in three possible transport strategies: unimanual transport, handing off between hands, and symmetric bimanual transport. In this study, we investigate the effect of object size, weight, and starting and ending position (configuration) as well as the need to balance the object on the use of these three strategies in a bowl-moving task...
May 9, 2018: Journal of Motor Behavior
https://www.readbyqxmd.com/read/29733581/dual-analyte-fluorescent-sensor-based-on-5-helicene-derivative-with-super-large-stokes-shift-for-the-selective-determinations-of-cu2-or-zn2-in-buffer-solutions-and-its-application-in-living-cell
#9
Siwakorn Sakunkaewkasem, Anuwut Petdum, Waraporn Panchan, Jitnapa Sirirak, Adisri Charoenpanich, Thanasat Sooksimuang, Nantanit Wanichacheva
A new fluorescent sensor, M201-DPA, based on [5]helicene derivative was utilized as dual-analyte sensor for determination of Cu2+ or Zn2+ in different media and different emission wavelengths. The sensor could provide selective and bifunctional determination of Cu2+ in HEPES buffer containing Triton-X100 and Zn2+ in Tris buffer/methanol without the interfering from each other and other ions. In HEPES buffer, M201-DPA demonstrated the selective ON-OFF fluorescence quenching at 524 nm toward Cu2+. On the other hand, in Tris buffer/methanol, M201-DPA showed the selective OFF-ON fluorescence enhancement upon the addition of Zn2+, which was specified by the hypsochromic shift at 448 nm...
May 7, 2018: ACS Sensors
https://www.readbyqxmd.com/read/29730963/screening-for-intellectual-disabilities-a-validation-of-the-hayes-ability-screening-index-for-in-patients-with-substance-use-disorder
#10
Kirsten J Braatveit, Torbjørn Torsheim, Oddbjørn Hove
BACKGROUND: There is a reason to believe that many individuals with substance use disorder (SUD) in contact with services have an undiagnosed intellectual disability (ID). Assessing ID in persons with SUD can be challenging due to the influence of substances, time consumption, and specific requirements for the education of the assessor. On the other hand, an undiagnosed condition may lead to a lack of treatment adjustment and may result in drop-out from treatment or lack of treatment effect...
May 7, 2018: Nordic Journal of Psychiatry
https://www.readbyqxmd.com/read/29730096/a-qualitative-exploration-of-techniques-used-by-expert-midwives-to-preserve-the-perineum-intact
#11
C Begley, K Guilliland, L Dixon, M Reilly, C Keegan, C McCann, V Smith
BACKGROUND: The perineum stretches during birth to allow passage of the baby, but 85% of women sustain some degree of perineal trauma during childbirth, which is painful post-partum. Episiotomy rates vary significantly, with some countries having rates of >60%. Recent Irish and New Zealand studies showed lower severe perineal trauma and episiotomy rates than other countries. AIM: To explore expert Irish and New Zealand midwives' views of the skills that they employ in preserving the perineum intact during spontaneous vaginal birth...
May 2, 2018: Women and Birth: Journal of the Australian College of Midwives
https://www.readbyqxmd.com/read/29721873/-hands-off-the-ultrasound
#12
REVIEW
Johannes Porz, Manuela Klaschik
No abstract text is available yet for this article.
May 2018: MMW Fortschritte der Medizin
https://www.readbyqxmd.com/read/29708380/reconceptualizing-perceptual-load-as-a-rate-problem-the-role-of-time-in-the-allocation-of-selective-attention
#13
Zhi Li, Keyun Xin, Wei Li, Yanzhe Li
In the literature about allocation of selective attention, a widely studied question is when will attention be allocated to information that is clearly irrelevant to the task at hand. The present study, by using convergent evidence, demonstrated that there is a trade-off between quantity of information present in a display and the time allowed to process it. Specifically, whether or not there is interference from irrelevant distractors depends not only on the amount of information present, but also on the amount of time allowed to process that information...
April 30, 2018: Journal of Experimental Psychology. Human Perception and Performance
https://www.readbyqxmd.com/read/29708341/allosteric-self-assembly-of-coordinating-terthiophene-amphiphile-for-triggered-light-harvesting
#14
Tian Huang, Zhiyang Zhu, Rongrong Xue, Tongyue Wu, Peilong Liao, Zeyu Liu, Yunlong Xiao, Jianbin Huang, Yun Yan
Allosteric regulation is extensively employed by Nature to achieve functional control of protein or DNA through triggered conformational change at a remote site. We report that similar strategy can be utilized in artificial self-assembly to control the self-assembled structure and its function. We show that on binding of metal ions to the head group of an amphiphile TTC4L, the conformational change may lead to change of the dipole orientation of the energy donor at the chain end. This on the one hand leads to drastically different self-assembled structure, on the other hand enables light-harvesting between the donor-acceptor...
April 30, 2018: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/29706412/handover-from-operating-theatre-to-the-intensive-care-unit-a-quality-improvement-study
#15
Andrea P Marshall, Georgia Tobiano, Niki Murphy, Greg Comadira, Nicola Willis, Therese Gardiner, Lucy Hervey, Wendy Simpson, Brigid M Gillespie
BACKGROUND: Transitioning a patient from the operating theatre (OT) to the intensive care unit (ICU) is a dynamic and complex process. Handover of the critically ill postoperative patient can contribute to procedural and communication errors. Standardised protocols are means for structuring and improving handover content. Both have been shown to be effective in reducing information omission and improve communication during this transition period. OBJECTIVES: The aim of this uncontrolled before and after study was to improve handover processes and communication about the care for critically ill patients transferred from OT to ICU...
April 26, 2018: Australian Critical Care: Official Journal of the Confederation of Australian Critical Care Nurses
https://www.readbyqxmd.com/read/29706157/what-happens-to-disinhibited-social-engagement-disorder-over-time
#16
EDITORIAL
Helen Minnis
Disinhibited social engagement disorder (DSED) is one of the most intriguing syndromes in child and adolescent psychiatry but also one of the least understood. We know little about its developmental course in different groups of children, so I was delighted to see the incisive longitudinal work from the Bucharest Early Intervention Study by Guyon-Harris and colleagues.1 My own interest in DSED was sparked back in the early 1990s, when a travel bug had taken me to Guatemala and I had found a job in an orphanage...
May 2018: Journal of the American Academy of Child and Adolescent Psychiatry
https://www.readbyqxmd.com/read/29704753/does-exposure-to-pm-10-decrease-age-at-menarche
#17
Eun Mi Jung, Hae Soon Kim, Hyesook Park, Shinhee Ye, Dongheon Lee, Eun Hee Ha
BACKGROUND: There has been a consistent decrease in age at menarche in South Korea. A potential risk factor for early menarche is exposure to particulate matter (PM), because endocrine-disrupting compounds emitted into air from anthropogenic sources may be incorporated into PM. The objective of this study was to examine the association between pre-menarcheal exposure to PM ≤ 10 μm in diameter (PM10 ) and age at menarche in adolescents of South Korea using Korea National Health and Nutrition Examination Survey (KNHANES) 2010-2012 data...
April 25, 2018: Environment International
https://www.readbyqxmd.com/read/29700848/non-pharmacological-therapies-for-sleep-disturbances-in-people-with-parkinson-s-disease-a-systematic-review
#18
REVIEW
JuHee Lee, Yonji Kim, YieLin Kim
AIM: To determine the effectiveness of non-pharmacological therapies for sleep disturbances in people with Parkinson's disease. BACKGROUND: Sleep disturbances, which are common in people with Parkinson's disease, may diminish their quality of life. Non-pharmacological therapies are preferred over pharmacological therapies for improving sleep quality, owing to fewer adverse effects. DESIGN: Systematic literature review. DATA SOURCES: A systematic search of eight databases and hand searching was conducted for papers published between 1 January 1 2000 - 1 January 2016...
April 27, 2018: Journal of Advanced Nursing
https://www.readbyqxmd.com/read/29694472/phosphorescent-inner-filter-effect-based-sensing-of-xanthine-oxidase-and-its-inhibitors-with-mn-doped-zns-quantum-dots
#19
Dandan Tang, Jinyi Zhang, Rongxin Zhou, Ya-Ni Xie, Xiandeng Hou, Kailai Xu, Peng Wu
Overexpression and crystallization of uric acid have been recognized as the course of hyperuricemia and gout, which is produced via xanthine oxidase (XOD)-catalyzed oxidation of xanthine. Therefore, the medicinal therapy of hyperuricemia and gout is majorly based on the inhibition of the XOD enzymatic pathway. The spectroscopic nature of xanthine and uric acid, namely both absorption (near the ultraviolet region) and emission (non-fluorescent) characteristics, hinders optical assay development for XOD analysis...
April 25, 2018: Nanoscale
https://www.readbyqxmd.com/read/29689706/serological-tk1-predict-pre-cancer-in-a-routine-health-screenings-of-56-178-people
#20
Yu Wang, Xiaorong Jiang, Shasha Wang, Haixia Yu, Tingtin Zhang, Shuan Xu, Wenlong Li, Ellen He, Sven Skog
BACKGROUND: People with biomarkers above cut-off values normally have higher risk to develop pre-malignancies and malignancies. OBJECTIVE: Here we investigate if serological TK1 protein (STK1p), AFP, CEA and PSA below cut-off values predict development of pre-cancer. METHODS: The mean values and the concentration distribution of STK1p, AFP, CEA and PSA were determined in a cohort of 56,178 persons participating a health screening group, consist of people with non-tumor diseases, pre-malignancy and diseases associated with the risk process of malignancy...
April 6, 2018: Cancer Biomarkers: Section A of Disease Markers
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