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https://www.readbyqxmd.com/read/28540596/the-effect-of-growth-rate-and-ageing-on-colour-variation-of-european-pond-turtles
#1
Alejandro Ibáñez, José Martín, Alfonso Marzal, Albert Bertolero
Many chelonians have colourful dots, patches and stripes throughout their body that are made up, at least in part, of carotenoids. Therefore, turtles are very suitable models to study the evolution and functionality of carotenoid-based colouration. Recent studies suggested a close link between colouration and immune system in these taxa. However, more research is needed to understand the role of these colourful stripes and patches in turtle visual signalling. The purpose of this study was to explore the relationship between growth rate and colouration in European pond turtles...
June 2017: Die Naturwissenschaften
https://www.readbyqxmd.com/read/28537818/adolescent-and-young-adult-patients-with-cancer-perceptions-of-care
#2
Kayla N LaRosa, Marilyn Stern, Jennifer Bleck, Courtney Lynn, Janella Hudson, Damon R Reed, Gwendolyn P Quinn, Kristine A Donovan
BACKGROUND: Adolescent and young adults with cancer (AYACs) face unique medical, psychosocial, and supportive care needs. The purpose of this study was to identify AYACs perceptions and expectations of cancer care services on and off treatment. METHODS: Semistructured interviews were conducted with 23 AYACs aged 19-38 years (13 on and 10 off treatment), who were receiving care at a comprehensive cancer center. Verbatim transcripts were created from audiotaped interviews and hand coded using inductive content analysis methodology...
May 24, 2017: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/28533209/rationale-and-design-of-a-clinical-trial-to-evaluate-the-safety-and-efficacy-of-intracoronary-infusion-of-allogeneic-human-cardiac-stem-cells-in-patients-with-acute-myocardial-infarction-and-left-ventricular-dysfunction-the-randomized-multicenter-double-blind
#3
Ricardo Sanz-Ruiz, Ana Casado Plasencia, Luis R Borlado, María Eugenia Fernández-Santos, Reem Al-Daccak, Piet Claus, Itziar Palacios, Rafael Sádaba, Dominique Charron, Jan Bogaert, Miguel Mulet, Raquel Yotti, Inmaculada Gilaberte, Antonio Bernad, Javier Bermejo, Stefan Janssens, Francisco Fernández-Avilés
Rationale: Stem cell therapy has increased the therapeutic armamentarium in the fight against ischemic heart disease and heart failure (HF). The administration of exogenous stem cells has been investigated in patients suffering an acute myocardial infarction (AMI) with the final aim of salvaging jeopardized myocardium and preventing left ventricular adverse remodeling and functional deterioration. However, phase I and II clinical trials with autologous and "first-generation" stem cells have yielded inconsistent benefits and mixed results...
May 22, 2017: Circulation Research
https://www.readbyqxmd.com/read/28532579/interoceptive-ingredients-of-body-ownership-affective-touch-and-cardiac-awareness-in-the-rubber-hand-illusion
#4
Laura Crucianelli, Charlotte Krahé, Paul M Jenkinson, Aikaterini Katerina Fotopoulou
The sense of body ownership represents a fundamental aspect of bodily self-consciousness. Using multisensory integration paradigms, recent studies have shown that both exteroceptive and interoceptive information contribute to our sense of body ownership. Interoception refers to the physiological sense of the condition of the body, including afferent signals that originate inside the body and outside the body. However, it remains unclear whether individual sensitivity to interoceptive modalities is unitary or differs between modalities...
May 1, 2017: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/28528021/multicystic-peritoneal-mesothelioma-a-short-review
#5
Chi-Hao Zhang, Ji-Wei Yu, Meng Luo
Multicystic peritoneal mesothelioma (MCPM) is a rare neoplasm, predominantly affecting female patients during their reproductive years. The lesion is usually distributed diffusely in the abdomen and pelvis, but the peritoneum of the pelvic organs is the most common site. MCPM is composed of fluid-filled translucent cysts, connected by varying amounts of fibrous tissue, and lined by a layer of mesothelial cells. Because of the rarity of this disease, the pathogenesis and natural history of MCPM remain poorly understood and continuously debated...
March 31, 2017: Current Problems in Cancer
https://www.readbyqxmd.com/read/28527618/giving-the-tap-the-elbow-an-observational-study
#6
M Weinbren, L Bree, S Sleigh, M Griffiths
Hand washing is viewed as the most important barrier to cross infection. Incorrect use of clinical hand wash basins may lead to cross infection either from contaminated water or due to failure to decontaminate hands. Elbow operated taps used correctly prevent re-contamination of hands during operation. Observation shows many elbow operated taps are installed incorrectly with the handle flush with the back panel making it difficult to open using the elbow. AIM: To determine the effect of altering the angle of the handle of elbow operated taps on hand washing technique...
May 17, 2017: Journal of Hospital Infection
https://www.readbyqxmd.com/read/28511928/rational-design-of-nanoparticles-towards-targeting-antigen-presenting-cells-and-improved-t-cell-priming
#7
Eva Zupančič, Caterina Curato, Maria Paisana, Catarina Rodrigues, Ziv Porat, Ana S Viana, Carlos A M Afonso, João Pinto, Rogério Gaspar, João N Moreira, Ronit Satchi-Fainaro, Steffen Jung, Helena F Florindo
Vaccination is a promising strategy to trigger and boost immune responses against cancer or infectious disease. We have designed, synthesized and characterized aliphatic-polyester (poly(lactic-co-glycolic acid) (PLGA) nanoparticles (NP) to investigate how the nature of protein association (adsorbed versus entrapped) and polymer/surfactant concentrations impact on the generation and modulation of antigen-specific immune responses. The ability of the NP formulations to target dendritic cells (DC), be internalized and activate the T cells was characterized and optimized in vitro and in vivo using markers of DC activation and co-stimulatory molecules...
May 13, 2017: Journal of Controlled Release: Official Journal of the Controlled Release Society
https://www.readbyqxmd.com/read/28511661/a-preliminary-investigation-on-the-utility-of-temporal-features-of-force-myography-in-the-two-class-problem-of-grasp-vs-no-grasp-in-the-presence-of-upper-extremity-movements
#8
Gautam P Sadarangani, Carlo Menon
BACKGROUND: In upper-extremity stroke rehabilitation applications, the potential use of Force Myography (FMG) for detecting grasping is especially relevant, as the presence of grasping may be indicative of functional activity, which is a key goal of rehabilitation. To date, most FMG research has focused on the classification of the raw FMG signal (i.e. instantaneous FMG samples) in order to determine the state of the hand. However, given the temporal nature of force generation during grasping, the use of temporal feature extraction techniques may yield increased accuracy...
May 16, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/28509715/epidemic-of-isothiazolinone-allergy-in-north-america-prevalence-data-from-the-north-american-contact-dermatitis-group-2013-2014
#9
Matthew J Zirwas, Dathan Hamann, Erin M Warshaw, Howard I Maibach, James S Taylor, Denis Sasseville, Joel G DeKoven, Anthony F Fransway, C G Toby Mathias, Kathryn A Zug, Vincent A DeLeo, Joseph F Fowler, James G Marks, Melanie D Pratt, Donald V Belsito
BACKGROUND: Preservative sensitivity patterns evolve with changing use patterns in products. During the last decade, the use of methylisothiazolinone (MI) at higher concentrations in both leave-on and rinse-off products has significantly increased. This is the first North American Contact Dermatitis Group reporting cycle that includes both methylchloroisothiazolinone (MCI)/MI and MI data. OBJECTIVE: The aim of this study was to report the prevalence of isothiazolinone allergy (MCI/MI and MI) in the North American Contact Dermatitis Group patch-test population from January 1, 2013, to December 31, 2014...
May 2017: Dermatitis
https://www.readbyqxmd.com/read/28507470/evaluating-the-relationship-of-blood-pressure-plasma-angiotensin-peptides-and-aldosterone-with-cognitive-functions-in-patients-with-hypertension
#10
Selçuk Sen, Nermin Gürel, Baran Ufuktepe, Zeynep Günes Özünal, Çagla Büyüklü, Yagiz Üresin
Renin Angiotensin Aldosterone System (RAAS) plays an important role in the development of hypertension. On the other hand, hypertension is a well-known and independent risk factor for cognitive impairment. The aim of the present study was to evaluate the relationship of blood pressure control, plasma angiotensin peptides and aldosterone with cognitive functions. Forty-one patients who were under treatment with the same antihypertensive medications for at least three months were included in the study. Plasma angiotensin II, angiotensin 1-7, angiotensin IV, and aldosterone concentrations were analyzed using an enzyme-linked immunosorbent assay (ELISA)...
2017: EXCLI journal
https://www.readbyqxmd.com/read/28501580/can-the-acute-mri-features-reflect-neurological-prognosis-in-patients-with-cervical-spinal-cord-injury
#11
Akinobu Matsushita, Takeshi Maeda, Eiji Mori, Itaru Yuge, Osamu Kawano, Takayoshi Ueta, Keiichiro Shiba
BACKGROUND CONTEXT: Several prognostic studies looked for an association between the degree of SCI, as depicted by primary MRI within 72 hours of injury, and neurologic outcome.It was not clearly demonstrated whether the MRI at any time is to correlate with neurological prognosis. PURPOSE: The purpose of the present study was to investigate the relationship between the acute MRI features and neurological prognosis, especially walking ability of patients with cervical spinal cord injury (CSCI)...
May 10, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28501165/a-portable-somatic-cell-counter-based-on-a-multi-functional-counting-chamber-and-a-miniaturized-fluorescence-microscope
#12
Byeongyeon Kim, Yu Jin Lee, Jong Gwan Park, Dongwon Yoo, Young Ki Hahn, Sungyoung Choi
A somatic cell count is the concentration or density of somatic cells in milk, and is an important indicator for monitoring mastitis incidence and milk quality in the dairy industry. Managing and controlling mastitis based on somatic cell counts can help ensure high milk quality and yield. A major challenge when translating existing cell counting methods to such application is that they require off-chip sample preparation and complicated sample and reagent delivery steps that cannot be easily performed in resource-limited settings such as dairy farms...
August 1, 2017: Talanta
https://www.readbyqxmd.com/read/28499344/the-responsiveness-and-minimal-important-change-mic-of-the-western-ontario-shoulder-instability-index-wosi-and-oxford-shoulder-instability-score-osis
#13
Just A van der Linde, Derk A van Kampen, Loes W A H van Beers, Derek F P van Deurzen, Daniël B F Saris, Caroline B Terwee
Study Design A prospective cohort study. Background Patient Reported Outcome Measurements (PROMs) are widely used to evaluate functional limitations. Considering PROMs for shoulder instability, information is lacking with regard to what constitutes a relevant change from baseline scores. Objectives To evaluate the responsiveness of the Western Ontario Shoulder Instability Index (WOSI) and the Oxford Shoulder Instability Score (OSIS) and estimate their Minimal Important Change (MIC). Methods 105 consecutive patients with shoulder instability completed five PROMs at baseline and at 6-months follow-up...
May 12, 2017: Journal of Orthopaedic and Sports Physical Therapy
https://www.readbyqxmd.com/read/28496293/the-effect-of-dopaminergic-medication-on-joint-kinematics-during-haptic-movements-in-individuals-with-parkinson-s-disease
#14
Kuan-Yi Li, Pei-Yi Chu, Kristen A Pickett
This study examined whether altered joint angular motion during haptic exploration could account for a decline in haptic sensitivity in individuals with PD by analyzing joint position data during haptic exploration of a curved contour. Each participant's hand was passively moved by a robotic arm along the edges of a virtual box (5 cm × 15 cm) with a curved left wall. After each trial, participants indicated whether the contour was curved or straight. Visual, auditory, and tactile cues were occluded, and an electrogoniometer recorded shoulder and elbow joint angles during each trial...
2017: Behavioural Neurology
https://www.readbyqxmd.com/read/28488507/how-to-assist-patients-with-sit-stand-transfers
#15
Janice Taylor
Rationale and key points This article discusses optimal methods for assisting patients with sit-stand transfers where moving-and-handling equipment is not required. The article explains the importance of effective mobility care in optimising patients' rehabilitation and enhancing their independence. » The term 'assistance' is used in this article to refer to the support nurses can provide to patients during sit-stand transfers, but excludes manual assistance. Nurses should attempt various 'hands-off' mobility-enhancing strategies to assist the patient, such as the use of verbal, visual or light manual cues...
May 10, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28484860/anatomic-study-of-the-first-extensor-compartment-and-the-relationship-between-the-extensor-tendon-width-and-its-distal-insertion
#16
Shiro Sugiura, Yusuke Matsuura, Kazuki Kuniyoshi, Satoru Nishikawa, Takeshi Toyooka, Chisato Mori, Takane Suzuki
INTRODUCTION: The extensor pollicis brevis (EPB) tendon normally inserts into the base of the proximal phalanx of the thumb. However, a distal insertion of the EPB tendon into the thumb interphalangeal joint has been reported in refractory cases of de Quervain's disease. We hypothesized that the EPB tendon is wider beyond the thumb metacarpophalangeal joint in patients with extended EPB. This study aimed to evaluate the relationship between the extensor tendon width and the point of distal insertion of the EPB tendon...
May 8, 2017: Surgical and Radiologic Anatomy: SRA
https://www.readbyqxmd.com/read/28484791/varus-femoral-and-tibial-coronal-alignments-result-in-different-kinematics-and-kinetics-after-total-knee-arthroplasty
#17
Mutsumi Watanabe, Shinichi Kuriyama, Shinichiro Nakamura, Yoshihisa Tanaka, Kohei Nishitani, Moritoshi Furu, Hiromu Ito, Shuichi Matsuda
PURPOSE: Abnormal knee motion under various conditions has been described after total knee arthroplasty (TKA). However, differences in kinematics and kinetics of knees with varus femoral versus varus tibial alignment have not been evaluated. It was hypothesized that varus femoral and tibial alignments have the same impact on knee motion. METHODS: A musculoskeletal computer simulation was used. Femoral and tibial alignment in the coronal plane was each varied from neutral to 5° of varus in 1° increments...
May 8, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28483276/effectiveness-of-finger-marker-for-maintaining-the-correct-compression-point-during-paediatric-resuscitation-a-simulation-study
#18
Jae Yun Jung, Young Ho Kwak, Hyuksool Kwon, Yoo Jin Choi, Do Kyun Kim, Hee Chan Kim, Jung Chan Lee, Ji Heum Park, Hyungsoo Lim
OBJECTIVE: High-quality cardiopulmonary resuscitation is a significant factor for increasing the survival rate of paediatric patients. This study is to investigate the effectiveness of finger-marker stickers for maintaining the correct compression point during simulated infant cardiopulmonary resuscitation (CPR). METHODS: This crossover simulation study was conducted with 40 emergency physicians and paramedics at emergency departments of 2 tertiary hospitals. We used a remodeled infant CPR manikin developed to measure CPR quality indicators...
April 11, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28480195/alpha-interferon-treatment-in-hepatitis-b
#19
REVIEW
Aaron Shu Jeng Woo, Raymond Kwok, Taufique Ahmed
Pegylated interferon-α (PEG-IFN-α) is a first line option in the treatment of chronic hepatitis B. Compared with nucleos(t)ide analogues (NAs), therapy with PEG-IFN-α has the advantages of finite treatment duration and higher rates of hepatitis B surface antigen (HBsAg) and hepatitis B e antigen (HBeAg) seroconversion, but the disadvantage of greater adverse effects. Choosing PEG-IFN-α requires careful evaluation of the likelihood of achieving a sustained off-treatment response. Sustained off-treatment response with PEG-IFN-α can be predicted by baseline factors in HBeAg positive disease...
April 2017: Annals of Translational Medicine
https://www.readbyqxmd.com/read/28469889/a-quality-improvement-approach-to-standardization-and-sustainability-of-the-hand-off-process
#20
Craig Fryman, Carine Hamo, Siddharth Raghavan, Nirvani Goolsarran
There is mounting evidence that communication and hand-off failures are a root cause of two-thirds of sentinel events in hospitals. Several studies have shown that non-standardized hand-offs have yielded poor patient outcomes and adverse events. At Stony Brook University Hospital, there were numerous reported adverse events related to poor hand-off during the transfer of patient responsibility from one resident caregiver to the next. A resident-conducted root cause analysis identified lack of a standardized hand-off process and formal training on safe and efficient hand-off among caregivers as key contributing factors...
2017: BMJ Quality Improvement Reports
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