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https://www.readbyqxmd.com/read/27914851/dynapenia-and-metabolic-health-in-obese-and-nonobese-adults-aged-70%C3%A2-years-and-older-the-life-study
#1
Mylène Aubertin-Leheudre, Stephen Anton, Daniel P Beavers, Todd M Manini, Roger Fielding, Ann Newman, Tim Church, Stephen B Kritchevsky, David Conroy, Mary M McDermott, Anda Botoseneanu, Mary E Hauser, Marco Pahor
OBJECTIVE: The purpose of this study was to examine the relationship between dynapenia and metabolic risk factors in obese and nonobese older adults. METHODS: A total of 1453 men and women (age ≥70 years) from the Lifestyle Interventions and Independence for Elders (LIFE) Study were categorized as (1) nondynapenic/nonobese (NDYN-NO), (2) dynapenic/nonobese (DYN-NO), (3) nondynapenic/obese (NDYN-O), or (4) dynapenic/obese (DYN-O), based on muscle strength (Foundation for the National Institute of Health criteria) and body mass index...
November 30, 2016: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/27914613/association-between-cardiometabolic-index-and-erectile-dysfunction-a-new-index-for-predicting-cardiovascular-disease
#2
Murat Dursun, Huseyin Besiroglu, Alper Otunctemur, Emin Ozbek
Over the past decade, it has been suggested that erectile dysfunction (ED) is an early indicator of cardiovascular disease. In a recent study, a new index, termed as cardiometabolic index (CMI), was defined and measured as the product of triglyceride (TG)/high-density lipoprotein-cholesterol (HDL-C) ratio and waist-to-height ratio, which are good predictors of coronary artery disease and main components of metabolic syndrome (MetS). All components of the CMI are also included in MetS criteria. Thus, we decided to evaluate the correlation between CMI, including the criteria of MetS, and ED...
December 2016: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/27913580/responding-to-challenges-for-people-with-psychotic-illness-updated-evidence-from-the-survey-of-high-impact-psychosis
#3
REVIEW
Vera A Morgan, Anna Waterreus, Vaughan Carr, David Castle, Martin Cohen, Carol Harvey, Cherrie Galletly, Andrew Mackinnon, Patrick McGorry, John J McGrath, Amanda L Neil, Suzy Saw, Johanna C Badcock, Debra L Foley, Geoff Waghorn, Sarah Coker, Assen Jablensky
OBJECTIVE: The objective is to summarise recent findings from the 2010 Australian Survey of High Impact Psychosis (SHIP) and examine their implications for future policy and planning to improve mental health, physical health and other circumstances of people with a psychotic disorder. METHODS: Survey of High Impact Psychosis collected nationally representative data on 1825 people with psychotic illness. Over 60 papers have been published covering key challenges reported by participants: financial problems, loneliness and social isolation, unemployment, poor physical health, uncontrolled symptoms of mental illness, and lack of stable, suitable housing...
December 1, 2016: Australian and New Zealand Journal of Psychiatry
https://www.readbyqxmd.com/read/27912943/differences-in-energy-expenditure-during-high-speed-versus-standard-speed-yoga-a-randomized-sequence-crossover-trial
#4
Melanie Potiaumpai, Maria Carolina Massoni Martins, Roberto Rodriguez, Kiersten Mooney, Joseph F Signorile
OBJECTIVES: To compare energy expenditure and volume of oxygen consumption and carbon dioxide production during a high-speed yoga and a standard-speed yoga program. DESIGN: Randomized repeated measures controlled trial. SETTING: A laboratory of neuromuscular research and active aging. INTERVENTIONS: Sun-Salutation B was performed, for eight minutes, at a high speed versus and a standard-speed separately while oxygen consumption was recorded...
December 2016: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/27909725/lipoprotein-redox-status-evaluation-as-a-marker-of-cardiovascular-disease-risk-in-patients-with-inflammatory-disease
#5
Anca Ungurianu, Denisa Margină, Daniela Grădinaru, Claudia Băcanu, Mihaela Ilie, Christina Tsitsimpikou, Konstantinos Tsarouhas, Demetrios A Spandidos, Aristides M Tsatsakis
Patients with chronic inflammatory disorders (ID) have an increased risk of developing cardiovascular disease, and routinely determined parameters do not reveal the real metabolic status of specific subgroups, such as patients with rheumatoid arthritis (RA). In this study, in order to evaluate state of the art markers for the assessment of cardiometabolic risk, abnormalities in lipoprotein levels in patients with a low‑grade inflammatory status [diabetes mellitus (DM) subgroup] and in patients with a high systemic inflammatory burden (RA subgroup) was determined...
November 28, 2016: Molecular Medicine Reports
https://www.readbyqxmd.com/read/27906713/milk-fat-biomarkers-and-cardiometabolic-disease
#6
Ulf Risérus, Matti Marklund
PURPOSE OF REVIEW: Dairy is a major food group with potential impact on cardiometabolic health. Self-reported dairy intake has limitations that can partly be avoided by using biomarkers. This review aims to summarize the evidence of odd-chain saturated fatty acids (OCFAs), that is, pentadecanoic acid (C15 : 0) and heptadecanoic acid (17 : 0), as biomarkers of dairy fat intake. In addition, the associations of OCFA biomarkers with cardiometabolic disease will be overviewed. RECENT FINDINGS: Adipose tissue 15 : 0 is the preferred biomarker but also circulating 15 : 0, and to a weaker extent 17 : 0, reflects both habitual and changes in dairy intake...
November 30, 2016: Current Opinion in Lipidology
https://www.readbyqxmd.com/read/27905643/-inverse-association-of-cardiorespiratory-fitness-with-cardiovascular-risk-factors-in-chilean-adults
#7
Carlos Cristi-Montero, Rodrigo Ramírez-Campillo, Cristian Alvarez, Alex Garrido Méndez, María Adela Martínez, Ximena Díaz Martínez, Ana María Leiva, Carlos Salas, Manuel Gutiérrez, Ruth Sanzana-Inzunza, Eliana Durán, Ana María Labraña, Nicolás Aguilar-Farías, Carlos Celis-Morales
BACKGROUND: A high level of cardiorespiratory fitness (CRF) is an important protector against cardiovascular and metabolic diseases. AIM: To explore the association of CRF with several metabolic markers and estimate the variation of these parameters by an increase of 1 MET change in CRF. MATERIAL AND METHODS: Cross-sectional study of 447 adults (56% women) without medical history of cardiometabolic diseases. Physical activity evaluated using accelerometry, body mass index (BMI), blood pressure, blood glucose and insulin and lipid profile were measured...
August 2016: Revista Médica de Chile
https://www.readbyqxmd.com/read/27903520/visceral-adiposity-and-metabolic-syndrome-after-very-high-fat-and-low-fat-isocaloric-diets-a-randomized-controlled-trial
#8
Vivian L Veum, Johnny Laupsa-Borge, Øyvin Eng, Espen Rostrup, Terje H Larsen, Jan Erik Nordrehaug, Ottar K Nygård, Jørn V Sagen, Oddrun A Gudbrandsen, Simon N Dankel, Gunnar Mellgren
BACKGROUND: Different aspects of dietary pattern, including macronutrient and food profiles, may affect visceral fat mass and metabolic syndrome. OBJECTIVE: We hypothesized that consuming energy primarily from carbohydrate or fat in diets with similar food profiles would differentially affect the ability to reverse visceral adiposity and metabolic syndrome. DESIGN: Forty-six men (aged 30-50 y) with body mass index (in kg/m(2)) >29 and waist circumference >98 cm were randomly assigned to a very high-fat, low-carbohydrate (VHFLC; 73% of energy fat and 10% of energy carbohydrate) or low-fat, high-carbohydrate (LFHC; 30% of energy fat and 53% of energy carbohydrate) diet for 12 wk...
November 30, 2016: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/27901270/adipose-tissue-inflammation-by-intermittent-hypoxia-mechanistic-link-between-obstructive-sleep-apnoea-and-metabolic-dysfunction
#9
Silke Ryan
Obstructive sleep apnoea (OSA) is a highly prevalent condition and recognized as a major public health burden conveying a significant risk of cardiometabolic diseases and mortality. Type 2 diabetes (T2D), insulin resistance (IR) and glucose tolerance are common in subjects with OSA and this association is at least in part independent of the effects of obesity. Continuous positive airway pressure (CPAP) is the treatment of choice for the majority of patients with OSA but the benefit of CPAP on glycaemic health is uncertain...
November 29, 2016: Journal of Physiology
https://www.readbyqxmd.com/read/27900488/additive-antiatherogenic-effects-of-cetp-rs708272-on-serum-ldl-subfraction-levels-in-patients-with-chd-under-statin-therapy
#10
Deniz Kanca, Uzay Gormus, Bengu Tokat, Allison P Eronat, Zehra Bugra, Oğuz Ozturk, Hulya Yilmaz-Aydogan
Recently, subfraction analysis of serum low density lipoprotein (LDL) is considered to be a better predictor of the risk of coronary heart disease (CHD) compared to the other lipid parameters. The aim of this study was to examine the effects of the HDL-associated Taq1B (rs708272) SNP of cholesterol ester transfer protein (CETP) gene on serum LDL subfractions in patients with CHD. Serum lipid levels were measured enzymatically and LDL subfraction analysis was carried out by the Lipoprint System (Quantimetrix, CA, USA)...
November 30, 2016: Biochemical Genetics
https://www.readbyqxmd.com/read/27900447/controversies-about-sugars-results-from-systematic-reviews-and-meta-analyses-on-obesity-cardiometabolic-disease-and-diabetes
#11
REVIEW
Tauseef A Khan, John L Sievenpiper
Fructose-containing sugars are a focus of attention as a public health target for their putative role in obesity and cardiometabolic disease including diabetes. The fructose moiety is singled out to be the primary driver for the harms of sugars due to its unique endocrine signal and pathophysiological role. However, this is only supported by ecological studies, animal models of overfeeding and select human intervention studies with supraphysiological doses or lack of control for energy. The highest level of evidence from systematic reviews and meta-analyses of controlled trials has not shown that fructose-containing sugars behave any differently from other forms of digestible carbohydrates...
November 30, 2016: European Journal of Nutrition
https://www.readbyqxmd.com/read/27900077/selective-beneficial-cardiometabolic-effects-of-vertical-sleeve-gastrectomy-are-predominantly-mediated-through-glucagon-like-peptide-glp-1-in-zucker-diabetic-fatty-rats
#12
Sunil Kumar, Raymond Lau, Thomas Palaia, Christopher Hall, Jenny Lee, Keneth Hall, Collin E Brathwaite, Louis Ragolia
BACKGROUND: Glucagon-like peptide-1 (GLP-1) level was significantly increased post Vertical Sleeve Gastrectomy (VSG), an effect believed to contribute to its beneficial cardiometabolic effects. OBJECTIVE: To validate the beneficial GLP-1 mediated cardiometabolic effects post VSG using GLP-1 antagonist (exendin 9-39) in Zucker diabetic fatty rats. METHODS: Animals were divided into three (n = 5) groups: (i) sham, (ii) VSG, and (iii) VSG received exendin 9-39 (GLP-1 receptor antagonist)...
December 2016: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/27899895/developmental-origins-of-cardiometabolic-diseases-role-of-the-maternal-diet
#13
REVIEW
João H Costa-Silva, Aiany C Simões-Alves, Mariana P Fernandes
Developmental origins of cardiometabolic diseases have been related to maternal nutritional conditions. In this context, the rising incidence of arterial hypertension, diabetes type II, and dyslipidemia has been attributed to genetic programming. Besides, environmental conditions during perinatal development such as maternal undernutrition or overnutrition can program changes in the integration among physiological systems leading to cardiometabolic diseases. This phenomenon can be understood in the context of the phenotypic plasticity and refers to the adjustment of a phenotype in response to environmental input without genetic change, following a novel, or unusual input during development...
2016: Frontiers in Physiology
https://www.readbyqxmd.com/read/27895689/waist-to-height-ratio-as-a-screening-tool-for-obesity-and-cardiometabolic-risk
#14
REVIEW
Eun-Gyong Yoo
The waist-to-height ratio (WHtR), calculated by dividing the waist circumference (WC) by height, has recently gained attention as an anthropometric index for central adiposity. It is an easy-to-use and less age-dependent index to identify individuals with increased cardiometabolic risk. A WHtR cutoff of 0.5 can be used in different sex and ethnic groups and is generally accepted as a universal cutoff for central obesity in children (aged ≥6 years) and adults. However, the WHtR has not been validated in preschool children, and the routine use of WHtR in children under age 6 is not recommended...
November 2016: Korean Journal of Pediatrics
https://www.readbyqxmd.com/read/27895666/cardiometabolic-risk-in-hyperlipidemic-men-and-women
#15
Michael Leutner, Christian Göbl, Alice Wielandner, Eleonora Howorka, Marlies Prünner, Latife Bozkurt, Jürgen Harreiter, Helmut Prosch, Oliver Schlager, Silvia Charwat-Resl, Alexandra Kautzky-Willer
Objective. The aim of this study was to evaluate sex specific differences of metabolic and clinical characteristics of treated hyperlipidemic men and women (HL-men and HL-women). Methods. In this study vascular and metabolic characteristics of 35 HL-women and 64 HL-men were assessed. In addition a sex specific analysis of metabolic and nutritional habits of HL-patients with prediabetes (HL-IGR) was done. Results. HL-women were older and had favourable concentrations of high density lipoprotein cholesterol (HDL-cholesterol), triglycerides (TG), and triglyceride/HDL-cholesterol ratio (TG/HDL-ratio) but were also shown to have higher concentrations of lipoprotein-a compared to HL-men...
2016: International Journal of Endocrinology
https://www.readbyqxmd.com/read/27895108/the-effect-of-dietary-fish-oil-on-weight-gain-and-insulin-sensitivity-is-dependent-on-apoe-genotype-in-humanized-targeted-replacement-mice
#16
Kenna E Slim, David Vauzour, Noemi Tejera, Peter J Voshol, Aedin Cassidy, Anne Marie Minihane
We investigated the independent and interactive impact of the common APOE genotype and marine n-3 polyunsaturated fatty acids (PUFA) on the development of obesity and associated cardiometabolic dysfunction in a murine model. Human APOE3 and APOE4 targeted replacement mice were fed either a high-fat control diet (HFD) or a HFD supplemented with 3% n-3 PUFA from fish oil (HFD + FO) for 8 wk. We established the impact of intervention on food intake, bodyweight, and visceral adipose tissue (VAT) mass; plasma, lipids (cholesterol and triglycerides), liver enzymes, and adipokines; glucose and insulin during an intraperitoneal glucose tolerance test; and Glut4 and ApoE expression in VAT...
November 28, 2016: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
https://www.readbyqxmd.com/read/27893825/low-birth-weight-is-associated-with-a-decreased-overall-adult-health-status-and-reproductive-capability-results-of-a-cross-sectional-study-in-primary-infertile-patients
#17
Luca Boeri, Eugenio Ventimiglia, Paolo Capogrosso, Silvia Ippolito, Angela Pecoraro, Marco Paciotti, Roberta Scano, Alessandro Galdini, Luca Valsecchi, Enrico Papaleo, Francesco Montorsi, Andrea Salonia
Individuals born with low birth weight (LBW) risk cardiometabolic complications later in life. However the impact of LBW on general health status and male reproductive function has been scantly analysed. We investigated the clinical and seminal impact of different birth weights (BW) in white-European men presenting for primary couple's infertility. Demographic, clinical, and laboratory data from 827 primary infertile men were compared with those of 373 consecutive fertile men. Patients with BW ≤2500, 2500-4200, and ≥4200gr were classified as having LBW, normal (NBW), and high BW (HBW), respectively...
2016: PloS One
https://www.readbyqxmd.com/read/27893563/resistance-training-improves-muscle-function-and-cardiometabolic-risks-but-not-quality-of-life-in-older-people-with-type-2-diabetes-mellitus-a-randomized-controlled-trial
#18
Ping-Lun Hsieh, Chin-Hsiao Tseng, Yufeng Jane Tseng, Wei-Shiung Yang
BACKGROUND AND PURPOSE: In older people with type 2 diabetes mellitus (T2DM), the effects of aging and T2DM may compromise the function of skeletal muscle, deteriorate metabolic status, and jeopardize physical performance, aerobic capacity, and quality of life (QoL). The purpose of this study was to investigate the effects of 12 weeks of resistance training (RT) on muscle function, physical performance, cardiometabolic risks, and QoL in older people with T2DM. METHODS: This study was a randomized controlled trial that employed block randomization, assessor blinding, and the intention-to-treat principle...
November 23, 2016: Journal of Geriatric Physical Therapy
https://www.readbyqxmd.com/read/27892780/associations-between-prolonged-sedentary-time-and-breaks-in-sedentary-time-with-cardiometabolic-risk-in-10-14-year-old-children-the-happy-study
#19
Daniel P Bailey, Sarah J Charman, Thomas Ploetz, Louise A Savory, Catherine J Kerr
This study examines the association between prolonged sedentary time and breaks in sedentary time with cardiometabolic risk in 10-14-year-old children. This cross-sectional design study analysed accelerometry-determined sedentary behaviour and physical activity collected over 7 days from 111 (66 girls) UK schoolchildren. Objective outcome measures included waist circumference, fasting lipids, fasting glucose, blood pressure, and cardiorespiratory fitness. Logistic regression was used for the main data analysis...
November 28, 2016: Journal of Sports Sciences
https://www.readbyqxmd.com/read/27892538/helicobacter-pylori-is-associated-with-dyslipidemia-but-not-with-other-risk-factors-of-cardiovascular-disease
#20
Tae Jun Kim, Hyuk Lee, Mira Kang, Jee Eun Kim, Yoon-Ho Choi, Yang Won Min, Byung-Hoon Min, Jun Haeng Lee, Hee Jung Son, Poong-Lyul Rhee, Sun-Young Baek, Soo Hyun Ahn, Jae J Kim
Epidemiologic and clinical data suggest that Helicobacter pylori infection is a contributing factor in the progression of atherosclerosis. However, the specific cardiovascular disease risk factors associated with H. pylori remain unclear. We performed a cross-sectional study of 37,263 consecutive healthy subjects who underwent a routine health check-up. In multivariable log Poisson regression models adjusted for potential confounders, the associations of H. pylori seropositivity with higher LDL-C (relative risk [RR], 1...
November 28, 2016: Scientific Reports
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