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https://www.readbyqxmd.com/read/29785272/abdominal-obesity-in-type-1-diabetes-associated-with-gender-cardiovascular-risk-factors-and-complications-and-difficulties-achieving-treatment-targets-a-cross-sectional-study-at-a-secondary-care-diabetes-clinic
#1
Eva O Melin, Hans O Thulesius, Magnus Hillman, Mona Landin-Olsson, Maria Thunander
Background: Abdominal obesity is linked to cardiovascular diseases in type 1 diabetes (T1D). The primary aim was to explore associations between abdominal obesity and cardiovascular complications, metabolic and inflammatory factors. The secondary aim was to explore whether achieved recommended treatment targets differed between the obese and non-obese participants. Methods: Cross sectional study of 284 T1D patients (age 18-59 years, men 56%), consecutively recruited from one secondary care specialist diabetes clinic in Sweden...
2018: BMC Obesity
https://www.readbyqxmd.com/read/29780641/association-of-abo-blood-group-and-body-mass-index-a-cross-sectional-study-from-a-ghanaian-population
#2
Samuel Smith, Isaac Okai, Chrissie Stansie Abaidoo, Emmanuel Acheampong
ABO blood group and body mass index (BMI) have individually been appraised as risk factors for certain diseases. From statistical perspective, it may be important to examine the relationship between the ABO blood antigen and BMI. This cross-sectional study involved 412 participants aged 18 to 46 at the Kwame Nkrumah University of Science and Technology (KNUST), Kumasi. Weight and height of participants were measured for BMI calculation; blood group determination was done using antisera. Blood group O was the most prevalent (51...
2018: Journal of Nutrition and Metabolism
https://www.readbyqxmd.com/read/29774602/pancreas-transplantation-using-compatible-but-non-identical-abo-blood-group-donors
#3
Santosh Nagaraju, Richard S Mangus, John A Powelson, Jonathan A Fridell
METHODS: A review of all pancreas transplants from a single institution from 01/2003 to 07/2016 (n=606) revealed 41 recipients of a NIC donor pancreas which were matched for age, race, gender, year and type of transplant with 41 ABO identical cases. Groups were compared for allograft survival, incidence of acute cellular rejection (ACR), length of hospital stay, 3-month readmissions and transfusion requirements. Serum haptoglobin and Lactate dehydrogenase were used to identify hemolysis in patients requiring repeated transfusions without overt blood loss...
May 17, 2018: Clinical Transplantation
https://www.readbyqxmd.com/read/29774557/diabetes-induced-microvascular-complications-at-the-level-of-the-spinal-cord-a-contributing-factor-in-diabetic-neuropathic-pain
#4
N Ved, M E Da Vitoria Lobo, S M Bestall, C L Vidueira, N Beazley-Long, K Ballmer-Hofer, M Hirashima, D O Bates, L F Donaldson, R P Hulse
Abnormalities of neurovascular interactions within the central nervous system of diabetic patients is associated with the onset of many neurological disease states. However, to date, the link between the neurovascular network within the spinal cord and regulation of nociception has not been investigated despite neuropathic pain being common in diabetes. We hypothesised that hyperglycaemia-induced endothelial degeneration in the spinal cord, due to suppression of VEGF-A/VEGFR2 signalling, induces diabetic neuropathic pain...
May 17, 2018: Journal of Physiology
https://www.readbyqxmd.com/read/29770457/abo-genotyping-with-next-generation-sequencing-to-resolve-heterogeneity-in-donors-with-serology-discrepancies
#5
Ping Chun Wu, Yin-Hung Lin, Lei Fang Tsai, Ming Hung Chen, Pei-Lung Chen, Shun-Chung Pai
BACKGROUND: ABO subtypes are characterized by the alteration of antigens present and their expression levels on red blood cells and many are linked to genetic changes in the ABO gene. Weakened expression of antigens should be identified to prevent transfusion reactions or ABO-incompatible transplantations. Genotyping can be applied to identify subtypes to complement serologic testing. Next-generation sequencing (NGS) has shown to provide sensitive and accurate genotyping results as well as valuable cis/trans information...
May 16, 2018: Transfusion
https://www.readbyqxmd.com/read/29769061/five-traditional-nigerian-polyherbal-remedies-protect-against-high-fructose-fed-streptozotocin-induced-type-2-diabetes-in-male-wistar-rats
#6
O E Kale, O B Akinpelu, A A Bakare, F O Yusuf, R Gomba, D C Araka, T O Ogundare, A C Okolie, O Adebawo, O Odutola
BACKGROUND: This present study sought to assess the modulatory effects of five Nigerian traditional polyherbal in high fructose-fed, streptozotocin-induced (HF-STZ) Type 2 diabetes (T2D) in rats. T2D was achieved via fructose feeding (20%W/V ) ad libitum for 2 weeks and streptozotocin (STZ, 40 mg/kg) (15th Day) intraperitoneally. METHODS: Seventy-two hours after STZ injection, fourty-eight diabetic rats were divided into eight of 6 rats/group: Diabetic normal untreated, glibenclamide (GBLI, 0...
May 16, 2018: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/29768642/-rhinocerebral-mucormycosis
#7
Anke Mertens, Christoph Arens, Doreen Barche, Laszlo Scheinpflug, Friedrich Gunther Scholz, Stefan Vielhaber, Cordula Scherlach, Uwe Tröger, Gernot Geginat, Jacqueline Färber
Mucormycosis is a rare but serious type of fungal infection, which can progress rapidly especially in immunsupressed patients.We report about a 47 year old female patient with ptosis on the left eye. The ophthalmological report offered no further pathologic findings. Diabetes mellitus was known and the blood sugar value was very high.A computed tomography of the paranasal sinuses showed a shadow in the ethmoid bone and in an additonally performed MRI-scan, an increase of orbital fat and an extension of the ocular muscle were visible...
May 16, 2018: Laryngo- Rhino- Otologie
https://www.readbyqxmd.com/read/29763980/arterial-stiffness-in-people-with-type-2-diabetes-and-obstructive-sleep-apnoea
#8
M Hvelplund Kristiansen, A M Banghøj, E Laugesen, L Tarnow
AIMS: To examine whether people with Type 2 diabetes with concurrent obstructive sleep apnoea have increased arterial stiffness as compared with people with Type 2 diabetes without obstructive sleep apnoea. METHODS: In a study with a case-control design, 40 people with Type 2 diabetes and treatment-naïve moderate to severe obstructive sleep apnoea (Apnoea-Hypopnoea Index ≥15) and a control group of 31 people with Type 2 diabetes without obstructive sleep apnoea (Apnoea-Hypopnoea Index <5) were examined...
May 15, 2018: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/29760188/depression-in-type-1-diabetes-was-associated-with-high-levels-of-circulating-galectin-3
#9
Eva O Melin, Jonatan Dereke, Maria Thunander, Magnus Hillman
OBJECTIVE: Neuroinflammatory responses are implicated in depression. The aim was to explore whether depression in patients with type 1 diabetes (T1D) was associated with high circulating galectin-3, controlling for metabolic variables, s-creatinine, life style factors, medication, and cardiovascular complications. DESIGN: Cross-sectional. METHODS: Participants were T1D patients (n=283, 56% men, age 18-59 years, diabetes duration ≥1 year)...
May 14, 2018: Endocrine Connections
https://www.readbyqxmd.com/read/29759105/the-glycaemic-index-and-insulinaemic-index-of-commercially-available-breakfast-and-snack-foods-in-an-asian-population
#10
Wei Shuan Kimberly Tan, Wei Jie Kevin Tan, Shalini D/O Ponnalagu, Katie Koecher, Ravi Menon, Sze-Yen Tan, Christiani J Henry
A low-glycaemic-index (GI) breakfast has been shown to lower blood glucose levels throughout the day. A wide variety of breakfast foods are consumed, but their GI values are largely unknown, hence limiting consumers' ability to select healthier options. This study investigated the GI values of ten common breakfast (five Asian and five Western) foods in this region using a randomised, cross-over study design. Participants arrived after an overnight fast, and fasting blood sample was taken before participants consumed test foods...
May 2018: British Journal of Nutrition
https://www.readbyqxmd.com/read/29756272/harnessing-human-decellularized-blood-vessel-matrices-and-cellular-construct-implants-to-promote-bone-healing-in-an-ex-vivo-organotypic-bone-defect-model
#11
Stefanie Inglis, Karl Heinrich Schneider, Janos M Kanczler, Heinz Redl, Richard O C Oreffo
Decellularized matrices offer a beneficial substitute for biomimetic scaffolds in tissue engineering. The current study examines the potential of decellularized placental vessel sleeves (PVS) as a periosteal protective sleeve to enhance bone regeneration in embryonic day 18 chick femurs contained within the PVS and cultured organotypically over a 10 day period. The femurs are inserted into decellularized biocompatibility-tested PVS and maintained in an organotypic culture for a period of 10 days. In femurs containing decellularized PVS, a significant increase in bone volume (p < 0...
May 14, 2018: Advanced Healthcare Materials
https://www.readbyqxmd.com/read/29754430/position-of-human-blood-group-o-h-and-phenotype-determining-enzymes-in-growth-and-infectious-disease
#12
REVIEW
Peter Arend
The human ABO(H) blood group phenotypes arise from the evolutionarily oldest genetic system found in primate populations. While the blood group antigen A is considered the ancestral primordial structure, under the selective pressure of life-threatening diseases blood group O(H) came to dominate as the most frequently occurring blood group worldwide. Non-O(H) phenotypes demonstrate impaired formation of adaptive and innate immunoglobulin specificities due to clonal selection and phenotype formation in plasma proteins...
May 12, 2018: Annals of the New York Academy of Sciences
https://www.readbyqxmd.com/read/29751628/the-double-face-of-mucin-type-o-glycans-in-lectin-mediated-infection-and-immunity
#13
REVIEW
Vasily Morozov, Julia Borkowski, Franz-Georg Hanisch
Epithelial human blood group antigens (HBGAs) on O-glycans play roles in pathogen binding and the initiation of infection, while similar structures on secretory mucins exert protective functions. These double-faced features of O-glycans in infection and innate immunity are reviewed based on two instructive examples of bacterial and viral pathogens. Helicobacter pylori represents a class 1 carcinogen in the human stomach. By expressing blood group antigen-binding adhesin ( BabA ) and LabA adhesins that bind to Lewis-b and LacdiNAc, respectively, H...
May 11, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29750885/severe-acute-heart-failure-experimental-model-with-very-low-mortality
#14
S Lacko, M Mlček, P Hála, M Popková, D Janák, M Hrachovina, J Kudlička, V Hrachovina, P Ošťádal, O Kittnar
The growth in the experimental research of facilities to support extracorporeal circulation requires the further development of models of acute heart failure that can be well controlled and reproduced. Two types of acute heart failure were examined in domestic pigs (Sus scrofa domestica): a hypoxic model (n = 5) with continuous perfusion of the left coronary artery by hypoxic deoxygenated blood and ischemic model (n = 9) with proximal closure of the left coronary artery and controlled hypoperfusion behind the closure...
May 10, 2018: Physiological Research
https://www.readbyqxmd.com/read/29750652/definition-of-reference-ranges-for-%C3%AE-isomerized-carboxy-terminal-telopeptide-collagen-type-i-for-children-and-adolescents
#15
Veronica C P de Melo, Paulo R S Ferreira, Lucelia O Ricardi, Marcelo C Batista, Carolina N França, Carlos E Dos S Ferreira
BACKGROUND: Bone metabolism involves many complex pathways that are disturbed by several bone diseases. The literature shows some limitations concerning pediatric reference intervals to bone markers, mainly because of the low number of patients included in the studies, the heterogeneity of methods, beyond the fact that it is time-consuming and expensive. The aim of this study was to determine reference values for β-isomerized carboxy-terminal telopeptides collagen type I (β-CTX), a marker of bone resorption, for children and adolescents...
May 11, 2018: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/29744251/comparison-of-different-cuff-pressure-use-with-the-supreme-laryngeal-mask-airway-on-haemodynamic-response-seal-pressure-and-postoperative-adverse-events-a-prospective-randomized-study
#16
Achmet Ali, Demet Altun, Nukhet Sivrikoz, Mesut Yornuk, Namigar Turgut, İbrahim Özkan Akıncı
Objective: The Supreme™ laryngeal mask airway (SLMA) is a supra glottic airway (SGA) device that is used as an alternative to endotracheal tubes. In the present study, we aimed to compare the use of the SLMA with normal cuff pressure and low cuff pressure, primarily for haemodynamic response. Methods: In the present study, 120 patients diagnosed with hypertension and scheduled for varicose vein or inguinal hernia operation were enrolled and 99 patients finished...
April 2018: Turkish Journal of Anaesthesiology and Reanimation
https://www.readbyqxmd.com/read/29742871/the-effect-of-abo-blood-groups-hemoglobinopathy-and-heme-oxygenase-1-polymorphisms-on-malaria-susceptibility-and-severity
#17
Jiraporn Kuesap, Kesara Na-Bangchang
Malaria is one of the most important public health problems in tropical areas on the globe. Several factors are associated with susceptibility to malaria and disease severity, including innate immunity such as blood group, hemoglobinopathy, and heme oxygenase-1 (HO-1) polymorphisms. This study was carried out to investigate association among ABO blood group, thalassemia types and HO-1 polymorphisms in malaria. The malarial blood samples were collected from patients along the Thai-Myanmar border. Determination of ABO blood group, thalassemia variants, and HO-1 polymorphisms were performed using agglutination test, low pressure liquid chromatography and polymerase chain reaction, respectively...
April 2018: Korean Journal of Parasitology
https://www.readbyqxmd.com/read/29742750/a-systematic-review-on-the-effectiveness-of-active-recovery-interventions-on-athletic-performance-of-professional-collegiate-and-competitive-level-adult-athletes
#18
Robert O Ortiz, Amanda J Sinclair Elder, Craig L Elder, J Jay Dawes
OrtizJr, RO, Sinclair Elder, AJ, Elder, CL, and Dawes, JJ. A systematic review on the effectiveness of active recovery interventions on athletic performance of professional-, collegiate-, and competitive-level adult athletes. J Strength Cond Res XX(X): 000-000, 2018-Active recovery (AR) is a popular approach to enhancing athlete recovery from participation through physical action, and it has a perceived benefit in the recovery of athletes' enhancement of postexertional physiological status; however, it is unclear whether these recovery techniques enhance athletic performance...
May 8, 2018: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29742662/patterns-of-von-willebrand-disease-screening-in-girls-and-adolescents-with-heavy-menstrual-bleeding
#19
Amanda E Jacobson, Sara K Vesely, Terah Koch, Janis Campbell, Sarah H OʼBrien
OBJECTIVE: To estimate the frequency of von Willebrand disease screening and factors that affect screening frequency in a national sample of girls and adolescents with heavy menstrual bleeding. METHODS: In this retrospective cohort study, we used a national claims database for privately and publicly insured patients between 2011 and 2013 for girls aged 10-17 years. Diagnostic criteria of heavy menstrual bleeding were the presence of one inpatient or two outpatient International Classification of Diseases, 9th Revision codes for heavy menstrual bleeding...
May 7, 2018: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29729165/modern-specific-features-and-therapy-of-psoriasis-and-arthropathic-psoriasis-courses
#20
Orysya O Syzon, Marianna O Dashko, Ulyana V Fedorova
OBJECTIVE: Introduction:Psoriasis affects about 2% of population. In 30-40% of occurrences arthropathic psoriasis (AP) is diagnosed and it leads to 11-19% of disability cases development. Recent studies have shown that psoriasis is often synergistically combined with herpesvirus of the 1st and 2nd type, which, according to many scientists, determines the severity, frequency of recurrences, and the course of this dermatosis. Recently, new biomarkers, i.e. a system of small ribonucleic microRNA acids, have been described...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
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