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https://www.readbyqxmd.com/read/29468787/association-of-dialysis-with-in-hospital-disability-progression-and-mortality-in-community-onset-stroke
#1
Tomoko Usui, Norio Hanafusa, Hideo Yasunaga, Masaomi Nangaku
AIM: End-stage renal disease is associated with increased risk of cerebrovascular disease, but the effect on post-stroke clinical outcomes has not been thoroughly investigated. METHODS: Using the Japanese Diagnosis Procedure Combination database, which includes administrative claims and discharge abstract data, we examined the association between risk factors including dialysis therapy and in-hospital disability progression or mortality in patients with community-onset stroke...
February 22, 2018: Nephrology
https://www.readbyqxmd.com/read/29468632/autonomic-function-test-in-progressive-lacunar-infarction
#2
S Y Ha, K M Park, J Park, S E Kim, B I Lee, K J Shin
OBJECTIVE: Neurological progression is a major problem in managing the patients with acute lacunar infarction. The purpose of this was to investigate whether autonomic dysfunction is associated with neurological progression in patients with acute lacunar infarction. MATERIALS AND METHODS: The study comprised 60 patients with acute lacunar infarction. All enrolled subjects underwent autonomic function tests including the 30° head-up tilt test, Valsalva test, heart rate response to deep breathing, and sympathetic skin response...
February 21, 2018: Acta Neurologica Scandinavica
https://www.readbyqxmd.com/read/29468623/isolated-basilar-artery-dissection-with-ischemic-stroke-report-of-4-cases
#3
Szu-Ju Chen, Li-Kai Tsai, Sung-Chun Tang, Jiann-Shing Jeng
PURPOSE: Isolated basilar artery dissection (BAD) is a rare cause of ischemic stroke. Since the clinical presentations and imaging findings could be non-specific and subtle, the diagnosis may be difficult. Here, we presented four cases of isolated BAD with acute ischemic stroke. CASE REPORT: Four patients (age, 22 to 57 years) experienced acute onset of hemiparesis and/or vertigo with half of them having initial headache. Acute infarct was noted at pons or thalamus...
September 15, 2017: Acta Neurologica Taiwanica
https://www.readbyqxmd.com/read/29468620/malnutrition-in-acute-stroke-patients-stratified-by-stroke-severity-a-hospital-based-study
#4
Dong-Yi Hsieh, Jen-Wen Hung, Ku-Chou Chang, Yu-Ching Huang, Tsong-Hai Lee, Hsiu-Min Chen
BACKGROUND: Stroke results in high mortality with tremendous health care burden. Malnutrition is frequently observed in patients after stroke. This study was designed to explore the nutritional status in the acute stage of stroke aiming at exploring factors related to malnutrition after stroke. METHODS: This was a hospital based, prospective, observational study recruiting cerebrovascular diseases patients hospitalized for acute management. Patients suffered from all kinds of cerebrovascular diseases hospitalized for management within 30 days after onset were consecutively recruited in the study hospitals...
September 15, 2017: Acta Neurologica Taiwanica
https://www.readbyqxmd.com/read/29468288/efficacy-of-mechanical-thrombectomy-using-stent-retriever-and-balloon-guiding-catheter
#5
S Kammerer, R du Mesnil de Rochemont, M Wagner, S -J You, S Tritt, M Mueller-Eschner, F C Keil, A Lauer, J Berkefeld
PURPOSE: Intra-arterial therapy of acute ischemic stroke has developed rapidly in recent years. Due to proven efficacy in randomized trials, stent retrievers were replacing first-generation thrombectomy devices and have been defined as method of choice. However, aspiration catheters or a combination of several techniques have shown promising rates of successful recanalizations. To create a basis for comparison of the new approaches according to real-world data, we determined the first pass recanalization rate of an evidence-based standard technique with the use of a stent retriever in combination with a balloon-guiding catheter...
February 21, 2018: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/29467716/tissue-is-more-important-than-time-in-stroke-patients-being-assessed-for-thrombolysis
#6
Andrew Bivard, Neil Spratt, Ferdinand Miteff, Christopher Levi, Mark William Parsons
Aim: The relative prognostic importance of modern imaging profiles compared with standard clinical characteristics is uncertain in acute stroke patients. In this study, we aimed to compare baseline multimodal CT imaging measures with known clinical predictors of patient outcome at 3 months [modified Rankin scale (mRS)]. Methods: We collected baseline, 24 h, and day 90 clinical and imaging data from acute ischemic stroke patients being assessed for thrombolytic therapy between 2010 and 2015 at a single center as part of a retrospective analysis...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/29467025/controlling-hypertension-after-severe-cerebrovascular-event-chase-study-protocol-for-a-randomized-controlled-trial
#7
Fang Yuan, Fang Yang, Changhu Xue, Kangjun Wang, Qiuwu Liu, Jun Zhou, Feng Fu, Xiaocheng Wang, Wei Zhang, Yi Liu, Kang Huo, Hua Lv, Wen Jiang
BACKGROUND: No ideal blood pressure (BP) range has been scientifically determined for acute stroke, and no studies on BP management have been carried out for patients with severe stroke. This trial aims to investigate whether individualized lowering of elevated BP would improve the outcome in patients with severe stroke. METHODS/DESIGN: The CHASE trial is a multicenter, randomized, controlled study. A total of 500 adult patients with acute severe stroke will be enrolled in 18 study sites in China and randomized to individualized BP lowering (10-15% reduction from admission level) or guideline-recommended BP lowering...
February 21, 2018: Trials
https://www.readbyqxmd.com/read/29466440/predictors-of-activities-of-daily-living-outcomes-after-upper-limb-robot-assisted-therapy-in-subacute-stroke-patients
#8
Marco Franceschini, Michela Goffredo, Sanaz Pournajaf, Stefano Paravati, Maurizio Agosti, Francesco De Pisi, Daniele Galafate, Federico Posteraro
BACKGROUND: Upper limb recovery is one of the main goals of post-stroke rehabilitation due to its importance for autonomy in Activities of Daily Living (ADL). Although the efficacy of upper limb Robot-assisted Therapy (RT) is well established in literature, the impact of the initial status of the patient on the effects of RT is still understudied. This paper aims to identify whether demographic, clinical and motor characteristics of stroke patients may influence the ability to independently perform ADL after RT...
2018: PloS One
https://www.readbyqxmd.com/read/29465097/quantitative-data-analysis-of-perceived-barriers-and-motivators-to-physical-activity-in-stroke-survivors
#9
S L Nicholson, C A Greig, F Sniehotta, M Johnston, S J Lewis, M E McMurdo, D Johnston, J Scopes, G E Mead
BACKGROUND: Levels of physical activity after stroke are low, despite multiple health benefits. We explored stroke survivors' perceived barriers, motivators, self-efficacy and intention to physical activity. METHODS: Fifty independently mobile stroke survivors were recruited prior to hospital discharge. Participants rated nine possible motivators and four possible barriers based on the Mutrie Scale, as having 'no influence', 'some influence' or 'a major influence' on physical activity...
September 2017: Journal of the Royal College of Physicians of Edinburgh
https://www.readbyqxmd.com/read/29464460/effects-of-hollow-fiber-membrane-oscillation-on-an-artificial-lung
#10
Ryan A Orizondo, Guy Gino, Garret Sultzbach, Shalv P Madhani, Brian J Frankowski, William J Federspiel
Gas transfer through hollow fiber membranes (HFMs) can be increased via fiber oscillation. Prior work, however, does not directly translate to present-day, full-scale artificial lungs. This in vitro study characterized the effects of HFM oscillations on oxygenation and hemolysis for a pediatric-sized HFM bundle. Effects of oscillation stroke length (2-10 mm) and frequency (1-25 Hz) on oxygen transfer were measured according to established standards. The normalized index of hemolysis was measured for select conditions...
February 20, 2018: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/29464375/association-between-marriage-and-outcomes-in-patients-with-acute-ischemic-stroke
#11
Qi Liu, Xianwei Wang, Yilong Wang, Chunxue Wang, Xingquan Zhao, Liping Liu, Zixiao Li, Xia Meng, Li Guo, Yongjun Wang
BACKGROUNDS: The previous studies on the association between marital status and stroke outcomes were rare. Furthermore, the existing studies mostly focused on the protective effect of marriage on survival. We conducted the study to evaluate the association between marital status and adverse stroke outcomes in patients with AIS based on China national stroke registry. METHODS: This was a multicenter, prospective cohort study of patients with AIS. Patients were classified into two groups based on marital status at admission: married and unmarried...
February 20, 2018: Journal of Neurology
https://www.readbyqxmd.com/read/29464140/a-case-report-of-recombinant-tissue-plasminogen-activator-use-in-a-span-100-positive-geriatric-patient-with-thrombocytopenia
#12
Ilya Bragin, Justine M Chen
Thrombocytopenia (platelet count: < 100,000/mm3 ) is considered a contraindication in the use of intravenous thrombolysis for acute ischemic stroke. Little literature exists regarding tissue plasminogen activator (tPA) usage in thrombocytopenic patients, especially in older patients. Age and stroke severity are major prognostic indicators of the risk of hemorrhagic transformation. The Stroke Prognostication using Age and NIH Stroke Scale (SPAN) index estimates a patient's risk of intracerebral hemorrhage (ICH) and clinical response to thrombolysis by combining age in years with the National Institutes of Health Stroke Scale (NIHSS) scores...
December 11, 2017: Curēus
https://www.readbyqxmd.com/read/29461514/a-large-open-source-dataset-of-stroke-anatomical-brain-images-and-manual-lesion-segmentations
#13
Sook-Lei Liew, Julia M Anglin, Nick W Banks, Matt Sondag, Kaori L Ito, Hosung Kim, Jennifer Chan, Joyce Ito, Connie Jung, Nima Khoshab, Stephanie Lefebvre, William Nakamura, David Saldana, Allie Schmiesing, Cathy Tran, Danny Vo, Tyler Ard, Panthea Heydari, Bokkyu Kim, Lisa Aziz-Zadeh, Steven C Cramer, Jingchun Liu, Surjo Soekadar, Jan-Egil Nordvik, Lars T Westlye, Junping Wang, Carolee Winstein, Chunshui Yu, Lei Ai, Bonhwang Koo, R Cameron Craddock, Michael Milham, Matthew Lakich, Amy Pienta, Alison Stroud
Stroke is the leading cause of adult disability worldwide, with up to two-thirds of individuals experiencing long-term disabilities. Large-scale neuroimaging studies have shown promise in identifying robust biomarkers (e.g., measures of brain structure) of long-term stroke recovery following rehabilitation. However, analyzing large rehabilitation-related datasets is problematic due to barriers in accurate stroke lesion segmentation. Manually-traced lesions are currently the gold standard for lesion segmentation on T1-weighted MRIs, but are labor intensive and require anatomical expertise...
February 20, 2018: Scientific Data
https://www.readbyqxmd.com/read/29461462/fes-assisted-cycling-improves-aerobic-capacity-and-locomotor-function-postcerebrovascular-accident
#14
Stacey E Aaron, Catherine J Vanderwerker, Aaron E Embry, Jennifer H Newton, Samuel C K Lee, Chris M Gregory
PURPOSE: After a cerebrovascular accident (CVA) aerobic deconditioning contributes to diminished physical function. Functional electrical stimulation (FES)-assisted cycling is a promising exercise paradigm designed to target both aerobic capacity and locomotor function. This pilot study aimed to evaluate the effects of an FES-assisted cycling intervention on aerobic capacity and locomotor function in individuals post-CVA. METHODS: Eleven individuals with chronic (>6 months) post-CVA hemiparesis completed an 8-wk (three times per week; 24 sessions) progressive FES-assisted cycling intervention...
March 2018: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/29460366/ejection-fraction-as-a-statistical-index-of-left-ventricular-systolic-function-the-first-full-allometric-scrutiny-of-its-appropriateness-and-accuracy
#15
Lorenzo Lolli, Alan M Batterham, Greg Atkinson
Left ventricular ejection fraction (EF) is a ratio that is deemed to accurately normalize stroke volume (SV) to end-diastolic volume (EDV). Ratios are now well-recognized for not normalizing the numerator, in this case SV, consistently for the denominator, EDV. We aimed to provide the first allometric-based scrutiny of the conventional assumptions that underpin the EF ratio. We allometrically modelled untransformed SV and EDV measurements from 112 preclinical heart failure patients in the Multi-Ethnic Study of Atherosclerosis (MESA), and 864 chronic heart failure patients in the Treatment of Preserved Cardiac Function Heart Failure with an Aldosterone Antagonist (TOPCAT) study...
February 20, 2018: Clinical Physiology and Functional Imaging
https://www.readbyqxmd.com/read/29460112/association-between-oral-contraceptives-and-risk-of-hemorrhagic-stroke-a-meta-analysis-of-observational-studies
#16
Zhenlin Xu, Yuanping Yue, Jianling Bai, Chong Shen, Jingjing Yang, Xiaoping Huang, Yang Zhao, Ying Li
OBJECTIVES: To estimate the risk of hemorrhagic stroke associated with current use of oral contraceptives (OCs), and to further depict how the risk was affected by study characteristics. METHODS: We searched PubMed, Embase, and Cochrane Library for relevant articles published up to February 2017 that examined the association between OC use and risk of hemorrhagic stroke. Two investigators independently reviewed articles based on inclusion criteria. The Newcastle-Ottawa scale was employed to evaluate quality of studies...
February 19, 2018: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29459469/female-sex-is-a-risk-modifier-rather-than-a-risk-factor-for-stroke-in-atrial-fibrillation-should-we-use-a-cha-2-ds-2-va-score-rather-than-cha-2-ds-2-vasc
#17
Peter Brønnum Nielsen, Flemming Skjøth, Thure Filskov Overvad, Torben Bjerregaard Larsen, Gregory Y H Lip
BACKGROUND: Stroke risk in atrial fibrillation is assessed by using the CHA2 DS2 -VASc score. Sex category (Sc, ie, female sex) confers 1 point on CHA2 DS2 -VASc. We hypothesized that female sex is a stroke risk modifier, rather than an overall risk factor, when added to a CHA2 DS2 -VA (sex-independent thromboembolism risk) score scale. METHODS: Using 3 nationwide registries, we identified patients with incident nonvalvular atrial fibrillation from January 1, 1997, through December 31, 2015...
February 20, 2018: Circulation
https://www.readbyqxmd.com/read/29459397/predictors-of-thrombolysis-administration-in-mild-stroke-florida-puerto-rico-collaboration-to-reduce-stroke-disparities
#18
Negar Asdaghi, Kefeng Wang, Maria A Ciliberti-Vargas, Carolina Marinovic Gutierrez, Sebastian Koch, Hannah Gardener, Chuanhui Dong, David Z Rose, Enid J Garcia, W Scott Burgin, Juan Carlos Zevallos, Tatjana Rundek, Ralph L Sacco, Jose G Romano
BACKGROUND AND PURPOSE: Mild stroke is the most common cause for thrombolysis exclusion in patients acutely presenting to the hospital. Thrombolysis administration in this subgroup is highly variable among different clinicians and institutions. We aim to study the predictors of thrombolysis in patients with mild ischemic stroke in the FL-PR CReSD registry (Florida-Puerto Rico Collaboration to Reduce Stroke Disparities). METHODS: Among 73 712 prospectively enrolled patients with a final diagnosis of ischemic stroke or TIA from January 2010 to April 2015, we identified 7746 cases with persistent neurological symptoms and National Institutes of Health Stroke Scale ≤5 who arrived within 4 hours of symptom onset...
February 19, 2018: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/29459395/effects-of-prehospital-thrombolysis-in-stroke-patients-with-prestroke-dependency
#19
Christian H Nolte, Martin Ebinger, Jan F Scheitz, Alexander Kunz, Hebun Erdur, Frederik Geisler, Tim-Bastian Braemswig, Michal Rozanski, Joachim E Weber, Matthias Wendt, Katja Zieschang, Jochen B Fiebach, Kersten Villringer, Ulrike Grittner, Sabina Kaczmarek, Matthias Endres, Heinrich J Audebert
BACKGROUND AND PURPOSE: Data on effects of intravenous thrombolysis on outcome of patients with ischemic stroke who are dependent on assistance in activities of daily living prestroke are scarce. Recent registry based analyses in activities of daily -independent patients suggest that earlier start of intravenous thrombolysis in the prehospital setting leads to better outcomes when compared with the treatment start in hospital. We evaluated whether these observations can be corroborated in patients with prestroke dependency...
February 19, 2018: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/29459394/hyperintense-vessels-collateralization-and-functional-outcome-in-patients-with-stroke-receiving-endovascular-treatment
#20
Alexander H Nave, Anna Kufner, Philipp Bücke, Eberhard Siebert, Stefan Kliesch, Ulrike Grittner, Hansjörg Bäzner, Thomas Liebig, Matthias Endres, Jochen B Fiebach, Christian H Nolte, Martin Ebinger, Hans Henkes
BACKGROUND AND PURPOSE: Fluid-attenuated inversion recovery hyperintense vessels (FHV) are frequently observed on magnetic resonance imaging in acute stroke patients with proximal vessel occlusion. Whether FHV can serve as a surrogate for the collateral status and predict functional outcome of patients is still a matter of debate. METHODS: Acute ischemic stroke patients with M1-middle cerebral artery occlusion who received magnetic resonance imaging before endovascular treatment in 3 hospitals in Germany between January 2007 and June 2016 were eligible...
February 19, 2018: Stroke; a Journal of Cerebral Circulation
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