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https://www.readbyqxmd.com/read/29690675/-update-on-2017-who-classification-of-tumors-of-thyroid-gland
#1
Z Y Liu, G Y Zhou, Kennichi Kakudo, Alfred K-Y Lam
No abstract text is available yet for this article.
April 8, 2018: Zhonghua Bing Li Xue za Zhi Chinese Journal of Pathology
https://www.readbyqxmd.com/read/29690556/fine-needle-aspiration-cytology-for-neck-masses-in-childhood-an-illustrative-approach
#2
REVIEW
Consolato Sergi, Aneesh Dhiman, Jo-Ann Gray
The primary indication of fine-needle aspiration cytology of the head and neck region is a thyroid nodule or a mass located in the cervical area or the head. Although a thyroid nodule may raise the suspicion of malignancy, less than one in 20 cases results in a carcinoma. In addition, the list of differential diagnoses is quite different according to the age of the patient. A number of benign lesions, such as branchial cysts, sialadenosis, and sialoadenitis are often seen in childhood and youth. The malignant lesions that are on the top of the list of a pediatric mass of the head and neck (H&N) region include rhabdomyosarcoma, neuroblastoma, and papillary carcinoma of the thyroid gland...
April 22, 2018: Diagnostics
https://www.readbyqxmd.com/read/29686785/primary-thyroid-maltoma-a-rare-diagnosis-of-an-unassuming-thyroid-nodule
#3
Pragya Shrestha, Kimberly Aderhold, Sharon Swierczynski, Catherine Lin, Ronald Herb
Primary thyroid lymphoma, although a rare malignancy, can arise in common chronic inflammatory conditions such as Hashimoto's thyroiditis. Incidental finding of a thyroid nodule with chronic thyroid inflammation warrants further investigation. Early detection of malignancy can play a vital role in improved outcomes. We report a case of a 60-year-old male who presented to the clinic for a routine visit. An enlarged, firm, non-tender thyroid gland was appreciated on exam with high thyroid stimulating hormone (TSH) level...
2018: Journal of Community Hospital Internal Medicine Perspectives
https://www.readbyqxmd.com/read/29685544/over-scanning-in-chest-ct-comparison-of-practice-among-six-hospitals-and-its-impact-on-radiation-dose
#4
Fides Schwartz, Bram Stieltjes, Zsolt Szucs-Farkas, André Euler
OBJECTIVES: Compare incidence of over-scanning in chest CT among six hospitals and impact on effective and organ effective radiation dose. METHODS: Scout images of 600 chest CTs from six hospitals (A-F) were retrospectively reviewed using a radiation dose tracking software (RTS). Optimal scan range was determined and compared to the actual scan range. Incidence of cranial and caudal over-scanning was assessed and changes in total and organ effective dose were calculated...
May 2018: European Journal of Radiology
https://www.readbyqxmd.com/read/29684947/-a-case-of-solitary-metastasis-of-renal-cell-carcinoma-to-the-thyroid-gland
#5
Yuki Yokoi, Kengo Yasuda, Hideyuki Terao, Shinpei Sugiura, Kazuo Kitami, Yuzo Minegishi, Shunichi Gondo
A case of solitary metastasis of renal cell carcinoma to the thyroid gland is presented. The patient was a 82-year-old man found to have an abnormal mass in his neck. He had a past history of renal clear cell carcinoma of the left kidney (pT1aN0M0, G1>2, alveolar type, clear cell subtype), which had been resected 12 years previously. Ultrasonography revealed a tumor mass in the right hemithyroid gland. This time fine needle biopsy of the thyroid tumor suggested metastatic thyroid carcinoma. Right hemithyroidectomy was performed last year...
February 2018: Hinyokika Kiyo. Acta Urologica Japonica
https://www.readbyqxmd.com/read/29684933/-dysphagia-from-a-gastroenterologist-s-perspective
#6
Marcus Hollenbach, Jürgen Feisthammel, Joachim Mössner, Albrecht Hoffmeister
Swallowing disorders (dysphagia) comprise a common cause of medical consultation and are defined as a subjective sensation of difficulty or abnormality of swallowing. In the initial step, a clear differentiation of dysphagia from odynophagia and globus sensation for further diagnostic procedures is mandatory. The careful questioning of patients symptoms and complaints is often helpful for the differentiation of oropharyngeal and esophageal dysphagia. Oropharyngeal dysphagia is mainly caused by neurological disorders (cerebral ischemia, Parkinson's disease, dementia) or local compression of malignancies, thyroid gland or lymph nodes...
May 2018: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/29681481/predictors-of-hypothyroidism-in-hodgkin-lymphoma-survivors-after-intensity-modulated-versus-3-dimensional-radiation-therapy
#7
Chelsea C Pinnix, Laura Cella, Therese Y Andraos, Zeina Ayoub, Sarah A Milgrom, Jillian Gunther, Sonali Thosani, Christine Wogan, Manuel Conson, Vittoria D'Avino, Yasuhiro Oki, Michelle Fanale, Hun J Lee, Sattva Neelapu, Luis Fayad, Frederick Hagemeister, M Alma Rodriguez, Loretta J Nastoupil, Yago Nieto, Wei Qiao, Roberto Pacelli, Bouthaina Dabaja
PURPOSE: To identify predictors of hypothyroidism after chemoradiation therapy for Hodgkin lymphoma (HL) and to compare outcomes after intensity modulated radiation therapy (IMRT) with those after 3-dimensional (3D) conformal radiation therapy (CRT). METHODS AND MATERIALS: Ninety patients who underwent involved-site IMRT in 2009 through 2014 were evaluated for treatment-induced hypothyroidism, defined as elevated thyroid-stimulating hormone or decreased free thyroxine levels (or both)...
March 14, 2018: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/29676367/sclerosing-mucoepidermoid-carcinoma-with-eosinophilia-of-thyroid-gland-not-so-indolent-a-neoplasm
#8
Anila Kunjulekshmi Amma Raveendran Nair, Nebu A George, Rejnish Kumar, A Sreekumar, K Jayasree
A 58-year-old female, a known diabetic and hypertensive, presented with left-sided swelling on the anterior aspect of the neck of 1-year duration, which was rapidly increasing in size for the past 6 months. She was on Eltroxin for hypothyroidism for the past 1 year. Computed tomography study of the neck showed a nodule in the left lobe of thyroid which on fine-needle aspiration was suspicious for malignancy. Total thyroidectomy with left posterolateral lymph node dissection was done. Histopathological examination showed sclerosing mucoepidermoid carcinoma with eosinophilia (SMECE) of the thyroid gland with lymph node metastasis...
April 2018: Indian Journal of Pathology & Microbiology
https://www.readbyqxmd.com/read/29674500/novel-gpr34-and-ccr6-mutation-and-distinct-genetic-profiles-in-malt-lymphomas-of-different-sites
#9
Sarah Moody, Joe Sneath Thompson, Shih-Sung Chuang, Hongxiang Liu, Markus Raderer, George Vassiliou, Iwona Wlodarska, Fangtian Wu, Sergio Cogliatti, Alistair Robson, Margaret Ashton-Key, Yingwen Bi, John Goodlad, Ming-Qing Du
MALT lymphoma originates from a background of diverse chronic inflammatory disorders at various anatomic sites. The genetics underlying its development, particularly in those associated with autoimmune disorders, is poorly characterised. By whole exome sequencing of 21 cases of MALT lymphomas of the salivary gland and thyroid, we have identified recurrent somatic mutations in 2 G-protein coupled receptors (GPR34 and CCR6) not previously reported in human malignancies, 3 genes (PIK3CD, TET2, TNFRSF14) not previously implicated in MALT lymphoma, and a further 2 genes (TBL1XR1, NOTCH1) recently described in MALT lymphoma...
April 19, 2018: Haematologica
https://www.readbyqxmd.com/read/29674245/effects-of-multiple-life-stage-exposure-to-the-fungicide-prochloraz-in-xenopus-laevis-manifestations-of-antiandrogenic-and-other-modes-of-toxicity
#10
Jonathan T Haselman, Patricia A Kosian, Joseph J Korte, Allen W Olmstead, Sigmund J Degitz
The Larval Amphibian Growth and Development Assay (LAGDA) is an internationally harmonized testing guideline for evaluating effects of chronic chemical exposure in amphibians. In order to evaluate the effects of chronic exposure to an antiandrogenic chemical in an amphibian model, prochloraz was tested using a variation of the LAGDA design. Exposure was initiated with <1d post-fertilization embryos at nominal concentrations of 0, 6.7, 20, 60 and 180 μg/L (0, 18, 53, 159, 478 nM) and continued in flow-through conditions until two months following the median time that controls completed metamorphosis...
April 3, 2018: Aquatic Toxicology
https://www.readbyqxmd.com/read/29672325/primary-mammary-analog-secretory-carcinoma-masc-of-the-vulva-with-etv6-ntrk3-fusion-a-case-report
#11
Jane K Nguyen, Julia A Bridge, Chandrika Joshi, Jesse K McKenney
Mammary analog secretory carcinoma is a primary salivary gland neoplasm with histologic, immunophenotypic, and molecular features identical to those of secretory carcinoma of the breast. Similar neoplasms have now been reported to occur in various nonmammary sites including the parotid gland, submandibular gland, sinuses, lip, skin, thyroid gland, and lung. We report, to our knowledge, the first example of a primary vulvar neoplasm with pathologic features identical to secretory carcinoma of the breast and an ETV6-NTRK3 fusion...
April 19, 2018: International Journal of Gynecological Pathology
https://www.readbyqxmd.com/read/29669433/investigation-on-aetiological-factors-in-patients-with-hyperhidrosis
#12
Ayşe Akbaş, Fadime Kilinç
BACKGROUND: Hyperhidrosis is a condition where the amount of sweat released to skin surface increases due to the over-active eccrine sweat glands. Hyperhidrosis causes considerable psychosocial distress in affected people. It affects the quality of life and leads to social anxiety disorders. AIMS: No study has been conducted in our country to investigate the epidemiological, clinical and laboratory data of patients with hyperhidrosis. In this study, we aimed to retrospectively investigate the clinical and demographic characteristics, causes of sweating and laboratory findings in patients treated for hyperhidrosis at our outpatient clinic and to compare these data with the literature data...
April 18, 2018: Cutaneous and Ocular Toxicology
https://www.readbyqxmd.com/read/29668629/asymptomatic-intrathyroidal-pyriform-sinus-fistula-mimicking-thyroid-cancer-a-case-report-and-literature-review
#13
Soo Chin Kim, Ji-Hoon Kim, Jae-Kyung Won, Eun Jae Chung
RATIONALE: There have been many reports of non-thyroidal lesions which can be mistaken for thyroidal lesions on ultrasound (US) examination. However, it is not known that pyriform sinus fistula (PSF) can manifest as an incidental thyroid nodule and cause serious complication on fine-needle aspiration (FNA). PATIENT CONCERNS: We present a 34-year-old man with PSF incidentally detected on US. US examination showed hypoechoic nodule with several bright echogenic spots at the uppermost part of left thyroid gland...
April 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29668454/identification-of-the-external-branch-of-the-superior-laryngeal-nerve-during-thyroid-surgery
#14
Lyubka Aleksova, Metin M Ali, Djevdet I Chakarov, Zeynep M Yozgyur
AIM: To compare the level of intra-operative identification of external branch of the superior laryngeal nerve (EBSLN) through classical conventional clinical methods of prevention against those applying intraoperative neuromonitoring (IONM). MATERIALS AND METHODS: The study included 102 patients with interventions on the thyroid gland performed in the surgical clinics of St George University Hospital and the Department of Special Surgery of Plovdiv Medical University...
March 1, 2018: Folia Medica
https://www.readbyqxmd.com/read/29666959/carney-complex-a-case-with-thyroid-follicular-adenoma-without-a-prkar1a-mutation
#15
Shinji Hattori, Yukou Yamane, Ryoichi Shimomura, Yuki Uchida, Nobuhiko Toyota, Yoshio Miura, Setsujyo Shiota, Yoshitsugu Tajima
BACKGROUND: Carney complex (CNC) is a very rare disease. Although thyroid lesions are included in the diagnostic criteria for CNC, they are an infrequent occurrence. CASE PRESENTATION: The patient was a 69-year-old woman who had undergone the removal of a left atrial myxoma 10 years earlier, at the age of 59. At the time of the operation, thyroid ultrasonography (US) revealed multiple hypoechoic nodules. Thyroid scintigraphy revealed an increased uptake of 99m Tc in these lesions, which was consistent with toxic multinodular goiter, and she was diagnosed with CNC...
April 17, 2018: Surgical Case Reports
https://www.readbyqxmd.com/read/29664539/-atypical-subacute-thyroiditis-in-combination-with-grave-s-disease-diagnostic-difficulties-in-a-case-report
#16
Emmanouela Koutouridou, Tereza Planck, Erik Uddman, Mikael Lantz
Subacute thyroiditis is a common inflammatory disorder of the thyroid gland, possibly of viral etiology, that typically presents with neck pain, fever and tenderness on palpation of the thyroid gland. Graves' disease is an autoimmune thyroid disorder caused by stimulation of the thyroid gland by thyrotropin receptor antibodies (TRAb). The development of Graves´ disease and subacute thyroiditis simultaneously is an uncommon condition and only a few cases have been reported. In this article we present a case of a 46-year old woman diagnosed with Graves´ disease who was started on thiamazole and weeks later developed high fever...
April 13, 2018: Läkartidningen
https://www.readbyqxmd.com/read/29663329/prophylactic-thyroidectomy-in-children-with-multiple-endocrine-neoplasia-type-2
#17
F P Prete, T Abdel-Aziz, C Morkane, C Brain, T R Kurzawinski
BACKGROUND: In patients with multiple endocrine neoplasia type 2 (MEN2) syndrome, genetic testing offers early diagnosis, stratifies the risk of developing medullary thyroid cancer (MTC) and informs the timing of thyroidectomy. The efficacy of treatment, which depends on timely and safe surgery, is not well established. METHODS: This was a retrospective review of diagnostic and clinicopathological outcomes of prophylactic thyroidectomy in children with MEN2 between 1995 and 2013 in the UK...
April 17, 2018: British Journal of Surgery
https://www.readbyqxmd.com/read/29661472/news-about-the-genetics-of-congenital-primary-adrenal-insufficiency
#18
Florence Roucher-Boulez, Delphine Mallet-Motak, Véronique Tardy-Guidollet, Rita Menassa, Claire Goursaud, Ingrid Plotton, Yves Morel
Primary adrenal insufficiency (PAI) is characterized by impaired production of steroid hormones due to an adrenal cortex defect. This condition incurs a risk of acute insufficiency which may be life-threatening. Today, 80% of pediatric forms of PAI have a genetic origin but 5% have no clear genetic support. Recently discovered mutations in genes relating to oxidative stress have opened the way to research on genes unrelated to the adrenal gland. Identification of causal mutations in a gene responsible for PAI allows genetic counseling, guidance of follow-up and prevention of complications...
April 13, 2018: Annales D'endocrinologie
https://www.readbyqxmd.com/read/29658811/parathyroid-autotransplantation-during-thyroid-surgery-where-we-are-a-systematic-review-on-indications-and-results
#19
Olga Iorio, Vincenzo Petrozza, Antonietta De Gori, Marco Bononi, Natale Porta, Giorgio De Toma, Giuseppe Cavallaro
INTRODUCTION: Hypoparathyroidism still represents an important concern in thyroid surgery. Careful dissection with identification and preservation of parathyroid glands in situ remains the best way to maintain gland vitality and avoid post-operative failure. Nevertheless, parathyroid glands are still inadvertently removed in up to 11% of cases. Parathyroid autotransplantation may represent the only way to restore parathyroid gland functionality in case of inadvertent removal or devascularization during thyroid surgery...
April 16, 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/29658781/evaluation-of-the-radiation-dose-in-the-thyroid-gland-using-different-protective-collars-in-panoramic-imaging
#20
Ladan Hafezi, Seyyedeh Marjan Arianezhad, Seyed Mahdi Hosseini Pooya
BACKGROUND: The value for the use of thyroid shield is one of the issues in radiation protection of patients in dental panoramic imaging. OBJECTIVES: The objective of this research is to investigate the attenuation characteristics of some models of thyroid shielding in dental panoramic examinations. METHODS: The effects of five different types of lead and lead-free (Pb-Equivalent) shields on dose reduction of thyroid gland were investigated using implanted TLDs in head-Neck parts of a Rando phantom...
April 16, 2018: Dento Maxillo Facial Radiology
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