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https://www.readbyqxmd.com/read/28339047/hypothalamo%C3%A2-hypophysial-system-in-rats-with-autotransplantation-of-the-adrenal-cortex
#1
Nae Takizawa, Susumu Tanaka, Souichi Oe, Taro Koike, Tadashi Matsuda, Hisao Yamada
Patients with bilateral pheochromocytoma often require an adrenalectomy. Autotransplantation of the adrenal cortex is an alternative therapy that could potentially be performed instead of receiving glucocorticoid replacement following adrenalectomy. Adrenal cortex autotransplantation aims to avoid the side effects of long‑term steroid treatment and adrenal insufficiency. Although the function of the hypothalamo‑hypophysial system is critical for patients who have undergone adrenal cortex autotransplantation, the details of that system, with the exception of adrenocorticotropic hormone in the subjects with adrenal autotransplantation, have been overlooked for a long time...
March 24, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28332158/first-clinical-use-of-the-echotrack-guidance-approach-for-radiofrequency-ablation-of-thyroid-gland-nodules
#2
Alfred Michael Franz, Alexander Seitel, Nasrin Bopp, Christian Erbelding, Dominique Cheray, Stefan Delorme, Frank Grünwald, Hüdayi Korkusuz, Lena Maier-Hein
PURPOSE: Percutaneous radiofrequency ablation (RFA) of thyroid nodules is an alternative to surgical resection that offers the benefits of minimal scars for the patient, lower complication rates, and shorter treatment times. Ultrasound (US) is the preferred modality for guiding these procedures. The needle is usually kept within the US scanning plane to ensure needle visibility. However, this restricts flexibility in both transducer and needle movement and renders the procedure difficult, especially for inexperienced users...
March 22, 2017: International Journal of Computer Assisted Radiology and Surgery
https://www.readbyqxmd.com/read/28332062/diagnosis-and-treatment-of-metastases-to-the-thyroid-gland-a-meta-analysis
#3
REVIEW
Patrizia Straccia, Claudia Mosseri, Chiara Brunelli, Esther Diana Rossi, Celestino Pio Lombardi, Alfredo Pontecorvi, Guido Fadda
The thyroid is a rare site of clinically detectable tumor metastases; even though the gland is a highly vascularized structure, the frequency of metastases in the routine practice is less than 0.2% of all thyroid malignancies. The purpose of our meta-analysis is to evaluate the frequency of metastatic diffusion from other primary tumors to the thyroid gland and to suggest the best possible treatment through an evidence-based study. Relevant studies were identified by searching the following databases: PubMed, Scopus, and Web of Science...
March 22, 2017: Endocrine Pathology
https://www.readbyqxmd.com/read/28330699/unusual-case-of-tumor-of-unknown-origin-found-by-18-f-fdg-pet-ct-metastatic-clear-cell-carcinoma-of-the-thyroid-gland
#4
G Treglia, P Trimboli, V Zilioli, F Fulciniti, L Giovanella
No abstract text is available yet for this article.
March 18, 2017: Revista Española de Medicina Nuclear e Imagen Molecular
https://www.readbyqxmd.com/read/28330547/-ectopic-thyroid-tissue-with-a-primary-carcinoma
#5
Pernille Hammershøj Jensen, Anette Pedersen Pilt, Hans-Erik Wittendorff
Ectopic thyroid tissue is a result of abnormal embryologic development and migration of the thyroid gland. It has a prevalence of one per 100,000-300,000, and the risk of malignant transformation in ectopic thyroid tissue is rare. We present a rare case of perivesical ectopic papillary thyroid carcinoma in a 76-year-old man with a normal orthotopic thyroid gland. A total thyroidectomy was performed, and the pathology report showed normal thyroid tissue with no neoplastic involvement. The patient was treated with radioactive iodine, and a control scintigraphy was without any signs of activity...
March 20, 2017: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/28330396/psychosocial-issues-related-to-thyroid-examination-after-a-radiation-disaster
#6
Sanae Midorikawa, Koichi Tanigawa, Satoru Suzuki, Akira Ohtsuru
A thyroid ultrasound examination program has been conducted in the aftermath of the Fukushima Daiichi Nuclear Power Plant accident to address concerns about the increased risk of thyroid cancer similar to those experienced by local residents after the 1986 Chernobyl accident. This is the second-largest thyroid cancer screening in younger age ever, following only that conducted after Chernobyl. As the natural history of thyroid cancer in younger populations is not well characterized, large-scale screening using thyroid ultrasound could result in overdiagnosis, even with careful planning, as has been experienced in South Korea...
March 2017: Asia-Pacific Journal of Public Health
https://www.readbyqxmd.com/read/28327204/lung-adenocarcinoma-with-thyroid-metastasis-a-case-report
#7
A Dao, H Jabir, A Taleb, N Benchakroun, Z Bouchbika, T Nezha, H Jouhadi, S Sahraoui, A Benider
BACKGROUND: The metastases of a primary lung cancer over the thyroid gland are extremely rare. We report on an unusual presentation of thyroid metastasis of lung cancer in order to improve the management of similar cases. CASE PRESENTATION: Three years ago, a Moroccan male 59-year-old was admitted for dyspnea, dry cough, and chest pain. He had smoked about 30 cigarette packs a year. Clinical examination revealed a right thyroid nodule. Chest and neck computed tomography (CT) scan showed a proximal left tumor in contact with the pulmonary artery and revealed a suspected nodule in the right lobe of the thyroid with homolateral neck node...
March 21, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28324012/deletion-of-the-thyroid-hormone-activating-type-2-deiodinase-rescues-cone-photoreceptor-degeneration-but-not-deafness-in-mice-lacking-type-3-deiodinase
#8
Lily Ng, Hong Liu, Donald L St Germain, Arturo Hernandez, Douglas Forrest
Type 2 deiodinase amplifies and type 3 deiodinase depletes levels of the active form of thyroid hormone, triiodothyronine (T3). Given the opposing activities of these enzymes, we tested the hypothesis that they counteract each other's developmental functions by investigating whether deletion of type 2 deiodinase (encoded by Dio2) modifies sensory phenotypes in type 3 deiodinase-deficient (Dio3-/-) mice. Dio3-/- mice display degeneration of retinal cones, the photoreceptors that mediate daylight and color vision...
March 7, 2017: Endocrinology
https://www.readbyqxmd.com/read/28323979/thyroid-cancer-following-childhood-low-dose-radiation-exposure-a-pooled-analysis-of-nine-cohorts
#9
Jay H Lubin, M Jacob Adams, Roy Shore, Erik Holmberg, Arthur B Schneider, Michael M Hawkins, Leslie L Robison, Peter D Inskip, Marie Lundell, Robert Johansson, Ruth A Kleinerman, Florent de Vathaire, Lena Damber, Siegal Sadetzki, Margaret Tucker, Ritsu Sakata, Lene H S Veiga
Context: The increased use of diagnostic and therapeutic procedures that involve radiation raises concerns about radiation effects, particularly in children and to the radio-sensitive thyroid gland. Objectives: Evaluation of relative risk (RR) trends for thyroid radiation doses <0.2 gray; evidence of a threshold dose; and possible modifiers of the dose-response, e.g., sex, age at exposure, time since exposure. Design and setting: Pooled data from nine cohort studies of childhood external radiation exposure and thyroid cancer with individualized dose estimates, ≥1,000 irradiated subjects or ≥10 thyroid cancer cases, with data limited to individuals receiving doses <0...
March 8, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28320460/thyroid-incidentalomas-on-18fdg-pet-ct-a-metabolico-pathological-correlation
#10
N Hagenimana, J Dallaire, É Vallée, M Belzile
BACKGROUND: Thyroid incidentaloma is defined as an unsuspected thyroid lesion found on imaging study or while performing a surgery non-related to the thyroid gland. Most recent scientific literature tends to demonstrate a detection rate of 0.1-4.3% for incidental findings of thyroid focal uptake identified by (18)F-fluorodeoxyglugose Positron Emission Tomography with computed tomography ((18)FDG-PET/CT) initially prescribed for nonthyroid disease. From 10.3 to 80.0% of patients who underwent further evaluation are diagnosed with malignant lesions...
March 21, 2017: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28320137/what-increases-the-risk-of-malnutrition-in-parkinson-s-disease
#11
Svetlana Tomic, Vlasta Pekic, Zeljka Popijac, Tomislav Pucic, Marta Petek, Tihana Gilman Kuric, Sanja Misevic, Ruzica Palic Kramaric
Parkinson's disease (PD) patients are at a higher risk of malnutrition. The prevalence has been estimated to 0-24%, while 3%-60% of PD patients are reported to be at risk of malnutrition. To date, there is no clear explanation for malnutrition in these patients. The aim of this study was to determine the prevalence of malnutrition and to analyze factors that influence its appearance. The Mini Nutritional Assessment (MNA) was used to determine normal nutritional status; at risk of malnutrition; and already malnourished status...
April 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28319287/iatrogenic-thyrotoxicosis-and-the-role-of-therapeutic-plasma-exchange
#12
Kabeer K Shah, Michael M Mbughuni, Edwin A Burgstaler, Darci R Block, Jeffrey L Winters
Thyroid storm or severe thyrotoxicosis results from extreme thyroid hormone elevation. Therapy includes medical management to prevent hormone production, release, recycling, and peripheral conversion while stabilizing adrenergic tone. Thyroid dysfunction is the usual cause but it can be due to excessive thyroid hormone ingestion. Therapeutic plasma exchange (TPE) has been used to rapidly remove protein-bound thyroid hormone. American Society for Apheresis guidelines make a weak recommendation to perform TPE in selected patients in the treatment of thyrotoxicosis based on low quality evidence...
March 20, 2017: Journal of Clinical Apheresis
https://www.readbyqxmd.com/read/28315910/effect-of-selenium-supplementation-for-protection-of-salivary-glands-from-iodine-131-radiation-damage-in-patients-with-differentiated-thyroid-cancer
#13
Haiyoung Son, Sang Mi Lee, Ra Gyoung Yoon, Hakmin Lee, Ilkyun Lee, Soon Kim, Woong Youn Chung, Jeong Won Lee
OBJECTIVE: In the current study, we examined whether selenium supplementation during iodine-131 ((131)I) treatment had a radio-protective effect on salivary glands. SUBJECTS AND METHODS: Sixteen patients with differentiated thyroid cancer were prospectively enrolled in the study. Patients after total thyroidectomy, before (131)I treatment, were divided into two groups; 8 patients in the selenium group and 8 patients in the control group. Patients in the selenium group received 300νg of selenium orally for 10 days, from 3 days before to 6 days after (131)I treatment...
March 20, 2017: Hellenic Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/28315908/positive-99m-tc-mibi-and-the-subtraction-parathyroid-scan-are-related-to-intact-parathyroid-hormone-but-not-to-total-plasma-calcium-in-primary-hyperparathyroidism
#14
Sanja Dugonjić, Marija Šišić, Marija Radulović, Boris Ajdinović
OBJECTIVE: Primary hyperparathyroidism (pHPT) is characterised by increased parathyroid hormone (PTH) secretion and consequently increased plasma calcium. During the last few decades parathyroid scintigraphy (PS), is applied in almost all patients with pPHT before surgery and specifically before minimally invasive parathyroidectomy. The aim of this study was to find the best cut-off levels of total plasma calcium and intact PTH (iPTH) that correlate with positive technetium-99m-methoxy isobutyl isonitrile ((99m)Tc-MIBI) PS and with positive subtraction PS (SPS) in patients with pHPT and thus the positive diagnostic value of these PS...
March 20, 2017: Hellenic Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/28306727/biodistribution-and-pet-imaging-of-pharmacokinetics-of-manganese-in-mice-using-manganese-52
#15
A Lake Wooten, Tolulope A Aweda, Benjamin C Lewis, Rebecca B Gross, Suzanne E Lapi
Manganese is essential to life, and humans typically absorb sufficient quantities of this element from a normal healthy diet; however, chronic, elevated ingestion or inhalation of manganese can be neurotoxic, potentially leading to manganism. Although imaging of large amounts of accumulated Mn(II) is possible by MRI, quantitative measurement of the biodistribution of manganese, particularly at the trace level, can be challenging. In this study, we produced the positron-emitting radionuclide 52Mn (t1/2 = 5.6 d) by proton bombardment (Ep<15 MeV) of chromium metal, followed by solid-phase isolation by cation-exchange chromatography...
2017: PloS One
https://www.readbyqxmd.com/read/28303870/-transoral-approach-to-thyroid-gland-in-the-experiment
#16
A M Shulutko, V I Semikov, S E Gryaznov, A V Gorbacheva, A R Patalova, G T Mansurova, Yu A Boblak
AIM: To develop minimally invasive and safe endoscopic access to thyroid gland. MATERIAL AND METHODS: Transoral pre-mandibular video-assisted gas-free access to thyroid gland was developed in experimental study that included 19 human cadavers. Stereometric modeling defined the evaluation criteria including the form of basal arch of lower jaw and its height. There was no conflict of instruments in working chamber under platysma. Additional trocar was deployed to resolve the conflict between working parts of instruments during thyroid gland mobilization...
2017: Khirurgiia
https://www.readbyqxmd.com/read/28303065/bilateral-lacrimal-caruncle-lesions
#17
Yuta Okumura, Yoshiko Takai, Shunsuke Yasuda, Hiroko Terasaki
A 65-year-old man was referred to our hospital for the treatment of a lesion on the medial lacrimal canthus of both eyes. He had a history of perinuclear anti-neutrophil cytoplasmic antibodies, i.e., pANCA-positive interstitial pneumonia. Orbital magnetic resonance imaging excluded space occupying lesions, and laboratory testing excluded thyroid-related diseases. The masses were excised, and histopathological examinations showed sebaceous gland hyperplasia and inflammatory changes around the gland. In addition, the specimen from the left eye showed a retention cyst possibly caused by an infection...
February 2017: Nagoya Journal of Medical Science
https://www.readbyqxmd.com/read/28300861/primary-cribriform-carcinoma-of-the-eyelid-with-neuroendocrine-features-a-case-report
#18
Joshua D Fox, Sander R Dubovy, Sara T Wester, Keyvan Nouri
A variety of tumors may involve the eyelid, most of which are primary, but rarely can be metastatic. Previously reported eyelid primary carcinomas with neuroendocrine features include Merkel cell carcinoma, apocrine and eccrine gland carcinoma, sebaceous gland carcinoma, and one report of primary "well-differentiated neuroendocrine tumor." Herein we report the first case of primary cribriform carcinoma of the eyelid with neuroendocrine features. The patient is a 75-year-old black man who presented to the clinic with a 5-year history of a slowly growing, non-painful, non-exudative lesion of his left lower eyelid...
February 1, 2017: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/28296787/unintentional-parathyroidectomy-during-total-thyroidectomy-surgery-a-single-surgeon-s-experience
#19
Wei Du, Qigen Fang, Xu Zhang, Meng Cui, Ming Zhao, Weihua Lou
In this study, we investigated incidental parathyroidectomy during total thyroidectomy surgery that required central lymph node dissection and the potential risk factors. Patients requiring total thyroidectomy and tracheoesophageal groove node dissection were enrolled in the study from January 2013 to June 2015 and we obtained all medical information, including pathology reports. Furthermore, we recorded the parathyroid hormone level in all patients prior to operation and then 3 further times: 1 day, 1 week, and 3 months after surgery...
March 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28295636/t-cell-lymphoblastic-lymphoma-leukemia-within-an-adrenocorticotropic-hormone-and-thyroid-stimulating-hormone-positive-pituitary-adenoma-a-cytohistological-correlation-emphasizing-importance-of-intra-operative-squash-smear
#20
Rakesh K Gupta, Ravindra K Saran, Arvind K Srivastava, Anita Jagetia, Lalit Garg, Mehar C Sharma
We present a rare case of primary pituitary T cell lymphoma/leukemia (T-LBL) in association with adrenocorticotropic hormone (ACTH) and thyroid stimulating hormone (TSH) expressing pituitary adenoma in a 55-year-old woman highlighting the importance of intra-operative squash smears examination. The patient presented with complaints of headache, diminution of vision and recent onset altered sensorium. MRI revealed a mass lesion in the sellar-suprasellar region with non-visualization of pituitary gland separately, extending to involve adjacent structures diagnosed as invasive pituitary macroadenoma...
March 13, 2017: Neuropathology: Official Journal of the Japanese Society of Neuropathology
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