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Jamie zhou

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https://www.readbyqxmd.com/read/29671322/utilizing-interlayer-excitons-in-bilayer-ws-2-for-increased-photovoltaic-response-in-ultrathin-graphene-vertical-cross-bar-photodetecting-tunneling-transistors
#1
Yingqiu Zhou, Haijie Tan, Yuewen Sheng, Ye Fan, Wenshuo Xu, Jamie H Warner
Here we study the layer-dependent photoconductivity in Gr/WS2 /Gr vertical stacked tunneling (VST) cross-bar devices made using two-dimensional (2D) materials all grown by chemical vapor deposition. The larger number of devices (>100) enables a statistically robust analysis on the comparative differences in the photovoltaic response of monolayer and bilayer WS2 , which cannot be achieved in small batch devices made using mechanically exfoliated materials. We show a dramatic increase in photovoltaic response for Gr/WS2 (2L)/Gr compared to monolayers because of the long inter- and intralayer exciton lifetimes and the small exciton binding energy (both interlayer and intralayer excitons) of bilayer WS2 compared with that of monolayer WS2 ...
April 19, 2018: ACS Nano
https://www.readbyqxmd.com/read/29629122/luminescent-zero-dimensional-organic-metal-halide-hybrids-with-near-unity-quantum-efficiency
#2
Chenkun Zhou, Haoran Lin, Yu Tian, Zhao Yuan, Ronald Clark, Banghao Chen, Lambertus J van de Burgt, Jamie C Wang, Yan Zhou, Kenneth Hanson, Quinton J Meisner, Jennifer Neu, Tiglet Besara, Theo Siegrist, Eric Lambers, Peter Djurovich, Biwu Ma
Single crystalline zero-dimensional (0D) organic-inorganic hybrid materials with perfect host-guest structures have been developed as a new generation of highly efficient light emitters. Here we report a series of lead-free organic metal halide hybrids with a 0D structure, (C4 N2 H14 X)4 SnX6 (X = Br, I) and (C9 NH20 )2 SbX5 (X = Cl), in which the individual metal halide octahedra (SnX6 4- ) and quadrangular pyramids (SbX5 2- ) are completely isolated from each other and surrounded by the organic ligands C4 N2 H14 X+ and C9 NH20 + , respectively...
January 21, 2018: Chemical Science
https://www.readbyqxmd.com/read/29543852/comparative-analysis-of-four-commercial-on-farm-culture-methods-to-identify-bacteria-associated-with-clinical-mastitis-in-dairy-cattle
#3
Jair C Ferreira, Marilia S Gomes, Erika C R Bonsaglia, Igor F Canisso, Edgar F Garrett, Jamie L Stewart, Ziyao Zhou, Fabio S Lima
Several multiple-media culture systems have become commercially available for on-farm identification of mastitis-associated pathogens. However, the accuracy of these systems has not been thoroughly and independently validated against microbiological evaluations performed by referral laboratories. Therefore, the purpose of the present study was to evaluate the performance of commercially available culture plates (Accumast, Minnesota Easy System, SSGN and SSGNC Quad plates) to identify pathogens associated with clinical mastitis in dairy cows...
2018: PloS One
https://www.readbyqxmd.com/read/29523786/cdk6-inhibits-white-to-beige-fat-transition-by-suppressing-runx1
#4
Xiaoli Hou, Yongzhao Zhang, Wei Li, Alexander J Hu, Chi Luo, Wenhui Zhou, Jamie K Hu, Stefano G Daniele, Jinfeng Wang, Jinghao Sheng, Yongsheng Fan, Andrew S Greenberg, Stephen R Farmer, Miaofen G Hu
Whereas white adipose tissue depots contribute to the development of metabolic diseases, brown and beige adipose tissue has beneficial metabolic effects. Here we show that CDK6 regulates beige adipocyte formation. We demonstrate that mice lacking the CDK6 protein or its kinase domain (K43M) exhibit significant increases beige cell formation, enhanced energy expenditure, better glucose tolerance, and improved insulin sensitivity, and are more resistant to high-fat diet-induced obesity. Re-expression of CDK6 in Cdk6-/- mature or precursor cells, or ablation of RUNX1 in K43M mature or precursor cells, reverses these phenotypes...
March 9, 2018: Nature Communications
https://www.readbyqxmd.com/read/29510053/revealing-strain-induced-effects-in-ultrathin-heterostructures-at-the-nanoscale
#5
Syed Ghazi Sarwat, Martin Tweedie, Benjamin F Porter, Yingqiu Zhou, Yuewen Sheng, Jan A Mol, Jamie H Warner, Harish Bhaskaran
Two dimensional materials are being increasingly studied, particularly for flexible and wearable technologies because of their inherent thickness and flexibility. Crucially, one aspect where our understanding is still limited is on the effect of mechanical strain, not on individual sheets of materials, but when stacked together as heterostructures in devices. In this paper, we demonstrate the use of Kelvin Probe Microscopy in capturing the influence of uniaxial tensile strain on the band-structures of Graphene and WS2 (mono and multi-layered) based heterostructures at high resolution...
March 6, 2018: Nano Letters
https://www.readbyqxmd.com/read/29449654/analysis-combining-correlated-glaucoma-traits-identifies-five-new-risk-loci-for-open-angle-glaucoma
#6
Puya Gharahkhani, Kathryn P Burdon, Jessica N Cooke Bailey, Alex W Hewitt, Matthew H Law, Louis R Pasquale, Jae H Kang, Jonathan L Haines, Emmanuelle Souzeau, Tiger Zhou, Owen M Siggs, John Landers, Mona Awadalla, Shiwani Sharma, Richard A Mills, Bronwyn Ridge, David Lynn, Robert Casson, Stuart L Graham, Ivan Goldberg, Andrew White, Paul R Healey, John Grigg, Mitchell Lawlor, Paul Mitchell, Jonathan Ruddle, Michael Coote, Mark Walland, Stephen Best, Andrea Vincent, Jesse Gale, Graham RadfordSmith, David C Whiteman, Grant W Montgomery, Nicholas G Martin, David A Mackey, Janey L Wiggs, Stuart MacGregor, Jamie E Craig
Open-angle glaucoma (OAG) is a major cause of blindness worldwide. To identify new risk loci for OAG, we performed a genome-wide association study in 3,071 OAG cases and 6,750 unscreened controls, and meta-analysed the results with GWAS data for intraocular pressure (IOP) and optic disc parameters (the overall meta-analysis sample size varying between 32,000 to 48,000 participants), which are glaucoma-related traits. We identified and independently validated four novel genome-wide significant associations within or near MYOF and CYP26A1, LINC02052 and CRYGS, LMX1B, and LMO7 using single variant tests, one additional locus (C9) using gene-based tests, and two genetic pathways - "response to fluid shear stress" and "abnormal retina morphology" - in pathway-based tests...
February 15, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29446624/hydrogen-assisted-growth-of-large-area-continuous-films-of-mos-2-on-monolayer-graphene
#7
Tongxin Chen, Yingqiu Zhou, Yuewen Sheng, Xiaochen Wang, Si Zhou, Jamie H Warner
We show how control over the chemical vapor deposition (CVD) reaction chemistry of molybdenum disulfide (MoS 2 ) by hydrogen addition can enable the direct growth of centimeter-scale continuous films of vertically stacked MoS 2 monolayer on graphene under atmospheric pressure conditions. Hydrogen addition enables longer CVD growth times at high temperature by reducing oxidation effects that would otherwise degrade the monolayer graphene. By careful control of nucleation density and growth time, high-quality monolayer MoS 2 films could be formed on graphene, realizing all CVD-grown vertically stacked monolayer semimetal/semiconducting interfaces...
February 15, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29360347/large-dendritic-monolayer-mos-2-grown-by-atmospheric-pressure-chemical-vapor-deposition-for-electrocatalysis
#8
Wenshuo Xu, Sha Li, Si Zhou, Ja Kyung Lee, Shanshan Wang, Syed Ghazi Sarwat, Xiaochen Wang, Harish Bhaskaran, Mauro Pasta, Jamie H Warner
The edge sites of MoS2 are catalytically active for the hydrogen evolution reaction (HER), and growing monolayer structures that are edge-rich is desirable. Here, we show the production of large-area highly branched MoS2 dendrites on amorphous SiO2 /Si substrates using an atmospheric pressure chemical vapor deposition and explore their use in electrocatalysis. By tailoring the substrate construction, the monolayer MoS2 evolves from triangular to dendritic morphology because of the change of growth conditions...
February 7, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29228253/rare-potentially-pathogenic-variants-in-znf469-are-not-enriched-in-keratoconus-in-a-large-australian-cohort-of-european-descent
#9
MULTICENTER STUDY
Sionne E M Lucas, Tiger Zhou, Nicholas B Blackburn, Richard A Mills, Jonathan Ellis, Paul Leo, Emmanuelle Souzeau, Bronwyn Ridge, Jac C Charlesworth, Matthew A Brown, Richard Lindsay, Jamie E Craig, Kathryn P Burdon
Purpose: The Zinc Finger Protein 469 (ZNF469) gene has been proposed as a candidate gene for keratoconus due to the association of an upstream polymorphism (rs9938149) with the disease in two independent studies, and the role of the gene in the autosomal recessive disease Brittle Cornea Syndrome. Coding variants in ZNF469 have been assessed for association with keratoconus in several small studies, with conflicting results. We assessed rare, potentially pathogenic variants in ZNF469 for enrichment in keratoconus patients in a cohort larger than all previous studies combined...
December 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/29197658/using-the-genome-aggregation-database-computational-pathogenicity-prediction-tools-and-patch-clamp-heterologous-expression-studies-to-demote-previously-published-long-qt-syndrome-type-1-mutations-from-pathogenic-to-benign
#10
Daniel J Clemens, Anne R Lentino, Jamie D Kapplinger, Dan Ye, Wei Zhou, David J Tester, Michael J Ackerman
BACKGROUND: Mutations in the KCNQ1-encoded Kv7.1 potassium channel cause long QT syndrome (LQTS) type 1 (LQT1). It has been suggested that ∼10%-20% of rare LQTS case-derived variants in the literature may have been published erroneously as LQT1-causative mutations and may be "false positives." OBJECTIVE: The purpose of this study was to determine which previously published KCNQ1 case variants are likely false positives. METHODS: A list of all published, case-derived KCNQ1 missense variants (MVs) was compiled...
December 2, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/29069077/functional-convergence-of-histone-methyltransferases-ehmt1-and-kmt2c-involved-in-intellectual-disability-and-autism-spectrum-disorder
#11
Tom S Koemans, Tjitske Kleefstra, Melissa C Chubak, Max H Stone, Margot R F Reijnders, Sonja de Munnik, Marjolein H Willemsen, Michaela Fenckova, Connie T R M Stumpel, Levinus A Bok, Margarita Sifuentes Saenz, Kyna A Byerly, Linda B Baughn, Alexander P A Stegmann, Rolph Pfundt, Huiqing Zhou, Hans van Bokhoven, Annette Schenck, Jamie M Kramer
Kleefstra syndrome, caused by haploinsufficiency of euchromatin histone methyltransferase 1 (EHMT1), is characterized by intellectual disability (ID), autism spectrum disorder (ASD), characteristic facial dysmorphisms, and other variable clinical features. In addition to EHMT1 mutations, de novo variants were reported in four additional genes (MBD5, SMARCB1, NR1I3, and KMT2C), in single individuals with clinical characteristics overlapping Kleefstra syndrome. Here, we present a novel cohort of five patients with de novo loss of function mutations affecting the histone methyltransferase KMT2C...
October 2017: PLoS Genetics
https://www.readbyqxmd.com/read/29044833/lateral-graphene-contacted-vertically-stacked-ws-2-mos-2-hybrid-photodetectors-with-large-gain
#12
Haijie Tan, Wenshuo Xu, Yuewen Sheng, Chit Siong Lau, Ye Fan, Qu Chen, Martin Tweedie, Xiaochen Wang, Yingqiu Zhou, Jamie H Warner
A demonstration is presented of how significant improvements in all-2D photodetectors can be achieved by exploiting the type-II band alignment of vertically stacked WS2 /MoS2 semiconducting heterobilayers and finite density of states of graphene electrodes. The photoresponsivity of WS2 /MoS2 heterobilayer devices is increased by more than an order of magnitude compared to homobilayer devices and two orders of magnitude compared to monolayer devices of WS2 and MoS2 , reaching 103 A W-1 under an illumination power density of 1...
December 2017: Advanced Materials
https://www.readbyqxmd.com/read/29023440/glaucoma-spectrum-and-age-related-prevalence-of-individuals-with-foxc1-and-pitx2-variants
#13
Emmanuelle Souzeau, Owen M Siggs, Tiger Zhou, Anna Galanopoulos, Trevor Hodson, Deepa Taranath, Richard A Mills, John Landers, John Pater, James E Smith, James E Elder, Julian L Rait, Paul Giles, Vivek Phakey, Sandra E Staffieri, Lisa S Kearns, Andrew Dubowsky, David A Mackey, Alex W Hewitt, Jonathan B Ruddle, Kathryn P Burdon, Jamie E Craig
This corrects the article DOI: 10.1038/ejhg.2017.59.
November 2017: European Journal of Human Genetics: EJHG
https://www.readbyqxmd.com/read/28941185/noninvasive-follicular-thyroid-neoplasm-with-papillary-like-nuclear-features-niftp-implications-for-the-risk-of-malignancy-rom-in-the-bethesda-system-for-reporting-thyroid-cytopathology-tbsrtc
#14
Haijun Zhou, Zubair W Baloch, Ritu Nayar, Tommaso Bizzarro, Guido Fadda, Deepti Adhikari-Guragain, Joseph Hatem, Luigi M Larocca, Julia Samolczyk, Jamie Slade, Esther Diana Rossi
BACKGROUND: The introduction of noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) affects the risk of malignancy (ROM) mostly in the Bethesda System for Reporting Thyroid Cytopathology (TBSRTC) categories. In this multi-institutional, retrospective study, the authors investigated variations in the impact of an NIFTP diagnosis on the associated ROM for each TBSRTC category with an emphasis on the influence of pathologist and institutional diagnostic thresholds on the ROM...
January 2018: Cancer Cytopathology
https://www.readbyqxmd.com/read/28854347/practical-immunohistochemistry-in-neoplastic-pathology-of-the-gastrointestinal-tract-liver-biliary-tract-and-pancreas
#15
REVIEW
Hanlin L Wang, Christopher J Kim, Jamie Koo, Wendi Zhou, Eunice K Choi, Ramir Arcega, Zongming Eric Chen, Huamin Wang, Lanjing Zhang, Fan Lin
CONTEXT: - Immunomarkers with diagnostic, therapeutic, or prognostic values have been increasingly used to maximize the benefits of clinical management of patients with neoplastic diseases of the gastrointestinal tract, liver, biliary tract, and pancreas. OBJECTIVES: - To review the characteristics of immunomarkers that are commonly used in surgical pathology practice for neoplasms of the gastrointestinal tract, liver, biliary tract, and pancreas, and to summarize the clinical usefulness of immunomarkers that have been discovered in recent years in these fields...
September 2017: Archives of Pathology & Laboratory Medicine
https://www.readbyqxmd.com/read/28829575/electrical-breakdown-of-suspended-mono-and-few-layer-tungsten-disulfide-via-sulfur-depletion-identified-by-in-situ-atomic-imaging
#16
Ye Fan, Alex W Robertson, Yingqiu Zhou, Qu Chen, Xiaowei Zhang, Nigel D Browning, Haimei Zheng, Mark H Rümmeli, Jamie H Warner
The high-bias and breakdown behavior of suspended mono- and few-layer WS2 was explored by in situ aberration-corrected transmission electron microscopy. The suspended WS2 devices were found to undergo irreversible breakdown at sufficiently high biases due to vaporization of the WS2. Simultaneous to the removal of WS2 was the accompanying formation of few-layer graphene decorated with W and WS2 nanoparticles, with the carbon source attributed to organic residues present on the WS2 surface. The breakdown of few-layer WS2 resulted in the formation of faceted S-depleted WS2 tendrils along the vaporization boundary, which were found to exhibit lattice contraction indicative of S depletion, alongside pure W phases incorporated into the structure, with the interfaces imaged at atomic resolution...
September 26, 2017: ACS Nano
https://www.readbyqxmd.com/read/28821666/gabaergic-interneuron-differentiation-in-the-basal-forebrain-is-mediated-through-direct-regulation-of-glutamic-acid-decarboxylase-isoforms-by-dlx-homeobox-transcription-factors
#17
Trung N Le, Qing-Ping Zhou, Inma Cobos, Shunzhen Zhang, Jamie Zagozewski, Sara Japoni, Jerry Vriend, Tracie Parkinson, Guoyan Du, John L Rubenstein, David D Eisenstat
GABA is the key inhibitory neurotransmitter in the cortex but regulation of its synthesis during forebrain development is poorly understood. In the telencephalon, members of the distal-less (Dlx) homeobox gene family are expressed in, and regulate the development of, the basal ganglia primodia from which many GABAergic neurons originate and migrate to other forebrain regions. The Dlx1/Dlx2 double knock-out mice die at birth with abnormal cortical development, including loss of tangential migration of GABAergic inhibitory interneurons to the neocortex (Anderson et al...
September 6, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28819194/hdac3-inhibition-ameliorates-spinal-cord-injury-by-immunomodulation
#18
Tomoharu Kuboyama, Shalaka Wahane, Yong Huang, Xiang Zhou, Jamie K Wong, Andrew Koemeter-Cox, Michael Martini, Roland H Friedel, Hongyan Zou
Following spinal cord injury (SCI), the innate immune response of microglia and infiltrating macrophages clears up cellular debris and promotes tissue repair, but it also inflicts secondary injury from inflammatory responses. Immunomodulation aimed at maximizing the beneficial effects while minimizing the detrimental roles of the innate immunity may aid functional recovery after SCI. However, intracellular drivers of global reprogramming of the inflammatory gene networks in the innate immune cells are poorly understood...
August 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28806992/comparison-of-an-alternative-schedule-of-extended-care-contacts-to-a-self-directed-control-a-randomized-trial-of-weight-loss-maintenance
#19
RANDOMIZED CONTROLLED TRIAL
Gareth R Dutton, Marissa A Gowey, Fei Tan, Dali Zhou, Jamy Ard, Michael G Perri, Cora E Lewis
BACKGROUND: Behavioral interventions for obesity produce clinically meaningful weight loss, but weight regain following treatment is common. Extended care programs attenuate weight regain and improve weight loss maintenance. However, less is known about the most effective ways to deliver extended care, including contact schedules. METHODS: We compared the 12-month weight regain of an extended care program utilizing a non-conventional, clustered campaign treatment schedule and a self-directed program among individuals who previously achieved ≥5% weight reductions...
August 15, 2017: International Journal of Behavioral Nutrition and Physical Activity
https://www.readbyqxmd.com/read/28723300/interest-in-using-mobile-technology-to-help-self-manage-alcohol-use-among-persons-living-with-the-human-immunodeficiency-virus-a-florida-cohort-cross-sectional-study
#20
J Danielle Sharpe, Zhi Zhou, César G Escobar-Viera, Jamie P Morano, Robert J Lucero, Gladys E Ibañez, Mark Hart, Christa L Cook, Robert L Cook
BACKGROUND: Alcohol consumption at hazardous levels is more prevalent and associated with poor health outcomes among persons living with the human immunodeficiency virus (HIV; PLWH). Although PLWH are receptive to using technology to manage health issues, it is unknown whether a cell phone app to self-manage alcohol use would be acceptable among PLWH who drink. The objectives of this study were to determine factors associated with interest in an app to self-manage drinking and to identify differences in baseline mobile technology use among PLWH by drinking level...
January 2, 2018: Substance Abuse
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