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https://www.readbyqxmd.com/read/28066820/hiv-care-providers-attitudes-regarding-mobile-phone-applications-and-web-based-dashboards-to-support-patient-self-management-and-care-coordination-results-from-a-qualitative-feasibility-study
#1
Dallas Swendeman, Shu Farmer, Deborah Mindry, Sung-Jae Lee, Melissa Medich
In-depth qualitative interviews were conducted with healthcare providers (HCPs) from five HIV medical care coordination teams in a large Los Angeles County HIV clinic, including physicians, nurses, and psychosocial services providers. HCPs reported on the potential utility, acceptability, and barriers for patient self-monitoring and notifications via mobile phones, and web-based dashboards for HCPs. Potential benefits included: 1) enhancing patient engagement, motivation, adherence, and self-management; and 2) improving provider-patient relationships and HCP care coordination...
October 2016: Journal of HIV and AIDS
https://www.readbyqxmd.com/read/28045615/cost-comparison-of-genetic-testing-strategies-in-women-with-epithelial-ovarian-cancer
#2
Jonathan R Foote, Micael Lopez-Acevedo, Adam H Buchanan, Angeles Alvarez Secord, Paula S Lee, Cynthia Fountain, Evan R Myers, David E Cohn, Shelby D Reed, Laura J Havrilesky
PURPOSE: The advent of multigene panels has increased genetic testing options for women with epithelial ovarian cancer (EOC). We designed a decision model to compare costs and probabilities of identifying a deleterious mutation or variant of uncertain significance (VUS) using different genetic testing strategies. METHODS: A decision model was developed to compare costs and outcomes of two testing strategies for women with EOC: multigene testing (MGT) versus single-gene testing for BRCA1/2...
January 3, 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/28032315/erratum-to-personal-identity-development-in-hispanic-immigrant-adolescents-links-with-positive-psychosocial-functioning-depressive-symptoms-and-externalizing-problems
#3
Seth J Schwartz, Jennifer B Unger, Alan Meca, Elma I Lorenzo-Blanco, Lourdes Baezconde-Garbanati, Miguel Ángel Cano, Brandy Piña-Watson, José Szapocznik, Byron L Zamboanga, David Córdova, Andrea J Romero, Tae Kyoung Lee, Daniel W Soto, Juan A Villamar, Karina M Lizzi, Sabrina E Des Rosiers, Monica Pattarroyo
No abstract text is available yet for this article.
December 28, 2016: Journal of Youth and Adolescence
https://www.readbyqxmd.com/read/27969754/tct-404-absorb-bioresorbable-vascular-scaffold-vs-everolimus-eluting-metallic-stent-in-st-segment-elevation-myocardial-infarction-bvs-examination-study-2-year-results-from-a-propensity-score-matched-comparison
#4
Salvatore Brugaletta, Tommaso Gori, Adrian Low, Petr Tousek, Eduardo Pinar Bermudez, Josep Gomez Lara, Luis Ortega-Paz, Eberhard Schulz, Mark Chan, Viktor Kocka, Jose Hurtado, Joan Antoni Gomez-Hospital, Thomas Muenzel, Chi-Hang Lee, Angel Cequier, Mariano Valdes, Petr Widimsky, Patrick Serruys, Manel Sabate
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27943007/the-impact-of-doctor-patient-communication-on-patients-perceptions-of-their-risk-of-breast-cancer-recurrence
#5
Nancy K Janz, Yun Li, Brian J Zikmund-Fisher, Reshma Jagsi, Allison W Kurian, Lawrence C An, M Chandler McLeod, Kamaria L Lee, Steven J Katz, Sarah T Hawley
PURPOSE: Doctor-patient communication is the primary way for women diagnosed with breast cancer to learn about their risk of distant recurrence. Yet little is known about how doctors approach these discussions. METHODS: A weighted random sample of newly diagnosed early-stage breast cancer patients identified through SEER registries of Los Angeles and Georgia (2013-2015) was sent surveys about ~2 months after surgery (Phase 2, N = 3930, RR 68%). We assessed patient perceptions of doctor communication of risk of recurrence (i...
December 9, 2016: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/27934961/minimum-electric-field-exposure-for-seizure-induction-with-electroconvulsive-therapy-and-magnetic-seizure-therapy
#6
Won Hee Lee, Sarah H Lisanby, Andrew F Laine, Angel V Peterchev
Lowering and individualizing the current amplitude in electroconvulsive therapy (ECT) has been proposed as a means to produce stimulation closer to the neural activation threshold and more focal seizure induction, which could potentially reduce cognitive side effects. However, the effect of current amplitude on the electric field (E-field) in the brain has not been previously linked to the current amplitude threshold for seizure induction. We coupled MRI-based E-field models with amplitude titrations of motor threshold (MT) and seizure threshold (ST) in four nonhuman primates (NHPs) to determine the strength, distribution, and focality of stimulation in the brain for four ECT electrode configurations (bilateral, bifrontal, right-unilateral, and frontomedial) and magnetic seizure therapy (MST) with cap coil on vertex...
December 9, 2016: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/27930912/poor-sleep-quality-antepartum-depression-and-suicidal-ideation-among-pregnant-women
#7
Bizu Gelaye, Gifty Addae, Beemnet Neway, Gloria T Larrabure-Torrealva, Chunfang Qiu, Lee Stoner, Miguel Angel Luque Fernandez, Sixto E Sanchez, Michelle A Williams
OBJECTIVE: To evaluate the independent and combined associations of maternal self-reported poor sleep quality and antepartum depression with suicidal ideation during the third trimester METHODS: A cross-sectional study was conducted among 1298 pregnant women (between 24 and 28 gestational weeks) attending prenatal clinics in Lima, Peru. Antepartum depression and suicidal ideation were assessed using the Patient Health Questionnaire-9 (PHQ-9). The Pittsburgh Sleep Quality Index (PSQI) questionnaire was used to assess sleep quality...
February 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/27917400/high-dose-biotin-treatment-for-secondary-progressive-multiple-sclerosis-may-interfere-with-thyroid-assays
#8
Alissa Minkovsky, Mark N Lee, Mitra Dowlatshahi, Trevor E Angell, Lilian S Mahrokhian, Athena K Petrides, Stacy E F Melanson, Ellen Marqusee, Whitney W Woodmansee
OBJECTIVE: To review cases and increase awareness in clinicians treating patients who may be taking biotin. METHODS: We describe the presentation and workup of a woman with secondary progressive multiple sclerosis on high dose biotin with laboratory studies suggestive of thyrotoxicosis. RESULTS: Plasma samples showed laboratory evidence of elevated thyroid hormone levels with elevated free thyroxine >7.8 ng/dl (reference interval (RI) 0...
2016: AACE Clin Case Rep
https://www.readbyqxmd.com/read/27914645/comparison-of-diverse-estimation-methods-for-personal-exposure-to-air-pollutants-and-associations-with-allergic-symptoms-the-allergy-gene-environment-link-angel-study
#9
Young-Min Kim, Jihyun Kim, Youngshin Han, Byung-Jae Lee, Dong-Chull Choi, Hae-Kwan Cheong, Byoung-Hak Jeon, Inbo Oh, Gwi-Nam Bae, Jae Young Lee, Chang-Heok Kim, SungChul Seo, Su Ryeon Noh, Kangmo Ahn
We estimated the exposure to ambient air pollutants and analyzed the associations with allergic diseases. We enrolled 177 children with atopic dermatitis (AD) and 70 asthmatic adults living in Seoul Metropolitan Area, Korea, and followed for 17months between August 2013 and December 2014. Parents or patients recorded symptom scores on a daily basis. Exposure to particulate matter with a diameter <10μm (PM10) and nitrogen dioxide (NO2) was estimated in four different ways in each individual, using the AQ1 (measurements from the nearest air quality monitoring station to residential houses), AQ2 (measurements modified from AQ1 with the indoor level of air pollutants and time activity of each individual), AQ1-DI, and AQ2-DI (measurements modified from AQ1 and AQ2, respectively, with daily inhalation intakes of air pollutants)...
February 1, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/27887877/a-discrete-stage-structured-model-of-california-newt-population-dynamics-during-a-period-of-drought
#10
Marjorie T Jones, William R Milligan, Lee B Kats, Thomas L Vandergon, Rodney L Honeycutt, Robert N Fisher, Courtney L Davis, Timothy A Lucas
We introduce a mathematical model for studying the population dynamics under drought of the California newt (Taricha torosa), a species of special concern in the state of California. Since 2012, California has experienced a record-setting drought, and multiple studies predict drought conditions currently underway will persist and even increase in severity. Recent declines and local extinctions of California newt populations in Santa Monica Mountain streams motivate our study of the impact of drought on newt population sizes...
November 22, 2016: Journal of Theoretical Biology
https://www.readbyqxmd.com/read/27884961/therapeutic-silencing-of-fat-specific-protein-27-improves-glycemic-control-in-mouse-models-of-obesity-and-insulin-resistance
#11
Cédric Langhi, Noemí Arias, Ananthi Rajamoorthi, Jeannine Basta, Richard G Lee, Ángel Baldán
Obesity is a component of the metabolic syndrome, mechanistically linked to diabetes, fatty liver disease, and cardiovascular disease. Proteins that regulate the metabolic fate of intracellular lipid droplets are potential therapeutic candidates to treat obesity and its related consequences. CIDEC (cell death-inducing DFFA-like effector C), also known in mice as Fsp27 (fat-specific protein 27), is a lipid droplet-associated protein that prevents lipid mobilization and promotes intracellular lipid storage. The consequences of complete loss of FSP27 on hepatic metabolism and on insulin resistance are controversial, as both healthy and deleterious lipodystrophic phenotypes have been reported in Fsp27(-/-) mice...
January 2017: Journal of Lipid Research
https://www.readbyqxmd.com/read/27882458/personal-identity-development-in-hispanic-immigrant-adolescents-links-with-positive-psychosocial-functioning-depressive-symptoms-and-externalizing-problems
#12
Seth J Schwartz, Jennifer B Unger, Alan Meca, Elma I Lorenzo-Blanco, Lourdes Baezconde-Garbanati, Miguel Ángel Cano, Brandy Piña-Watson, José Szapocznik, Byron L Zamboanga, David Córdova, Andrea J Romero, Tae Kyoung Lee, Daniel W Soto, Juan A Villamar, Karina M Lizzi, Sabrina E Des Rosiers, Monica Pattarroyo
The present study was designed to examine trajectories of personal identity coherence and confusion among Hispanic recent-immigrant adolescents, as well as the effects of these trajectories on psychosocial and risk-taking outcomes. Personal identity is extremely important in anchoring young immigrants during a time of acute cultural change. A sample of 302 recently immigrated (5 years or less in the United States at baseline) Hispanic adolescents (Mage = 14.51 years at baseline; SD = 0.88 years, range 14-17) from Miami and Los Angeles (47 % girls) completed measures of personal identity coherence and confusion at the first five waves of a six-wave longitudinal study; and reported on positive psychosocial functioning, depressive symptoms, and externalizing problems at baseline and at Time 6...
November 23, 2016: Journal of Youth and Adolescence
https://www.readbyqxmd.com/read/27864161/maintenance-versus-induction-therapy-choice-on-outcomes-after-autologous-transplantation-for-multiple-myeloma
#13
Robert F Cornell, Anita D'Souza, Adetola A Kassim, Luciano J Costa, Racquel D Innis-Shelton, Mei-Jie Zhang, Jiaxing Huang, Muneer Abidi, Jack Aiello, Gorgun Akpek, Asad Bashey, Qaiser Bashir, Jan Cerny, Raymond Comenzo, Miguel Angel Diaz, César Freytes, Robert Peter Gale, Siddhartha Ganguly, Mehdi Hamadani, Shahrukh Hashmi, Leona Holmberg, Nasheed Hossain, Rammurti T Kamble, Mohamed Kharfan-Dabaja, Tamila Kindwall-Keller, Robert Kyle, Shaji Kumar, Hillard Lazarus, Cindy Lee, Angelo Maiolino, David I Marks, Kenneth Meehan, Joe Mikhael, Rajneesh Nath, Taiga Nishihori, Richard F Olsson, Muthalagu Ramanathan, Ayman Saad, Sachiko Seo, Saad Usmani, David Vesole, Ravi Vij, Dan Vogl, Baldeep M Wirk, Jean Yared, Amrita Krishnan, Tomer Mark, Yago Nieto, Parameswaran Hari
Bortezomib (V), lenalidomide (R), cyclophosphamide (C), and dexamethasone (D) are components of the most commonly used modern doublet (RD, VD) or triplet (VRD, CVD) initial induction regimens before autologous hematopoietic cell transplantation (AHCT) for multiple myeloma (MM) in the United States. In this study we evaluated 693 patients receiving "upfront" AHCT after initial induction therapy with modern doublet or triplet regimens using data reported to the Center for International Blood and Marrow Transplant Research from 2008 to 2013...
February 2017: Biology of Blood and Marrow Transplantation
https://www.readbyqxmd.com/read/27851748/chromosomal-instability-estimation-based-on-next-generation-sequencing-and-single-cell-genome-wide-copy-number-variation-analysis
#14
Stephanie B Greene, Angel E Dago, Laura J Leitz, Yipeng Wang, Jerry Lee, Shannon L Werner, Steven Gendreau, Premal Patel, Shidong Jia, Liangxuan Zhang, Eric K Tucker, Michael Malchiodi, Ryon P Graf, Ryan Dittamore, Dena Marrinucci, Mark Landers
Genomic instability is a hallmark of cancer often associated with poor patient outcome and resistance to targeted therapy. Assessment of genomic instability in bulk tumor or biopsy can be complicated due to sample availability, surrounding tissue contamination, or tumor heterogeneity. The Epic Sciences circulating tumor cell (CTC) platform utilizes a non-enrichment based approach for the detection and characterization of rare tumor cells in clinical blood samples. Genomic profiling of individual CTCs could provide a portrait of cancer heterogeneity, identify clonal and sub-clonal drivers, and monitor disease progression...
2016: PloS One
https://www.readbyqxmd.com/read/27826293/assessing-marine-microbial-induced-corrosion-at-santa-catalina-island-california
#15
Gustavo A Ramírez, Colleen L Hoffman, Michael D Lee, Ryan A Lesniewski, Roman A Barco, Arkadiy Garber, Brandy M Toner, Charles G Wheat, Katrina J Edwards, Beth N Orcutt
High iron and eutrophic conditions are reported as environmental factors leading to accelerated low-water corrosion, an enhanced form of near-shore microbial induced corrosion. To explore this hypothesis, we deployed flow-through colonization systems in laboratory-based aquarium tanks under a continuous flow of surface seawater from Santa Catalina Island, CA, USA, for periods of 2 and 6 months. Substrates consisted of mild steel - a major constituent of maritime infrastructure - and the naturally occurring iron sulfide mineral pyrite...
2016: Frontiers in Microbiology
https://www.readbyqxmd.com/read/27816212/novel-presenilin-1-mutation-p-f386i-in-a-chinese-family-with-early-onset-alzheimer-s-disease
#16
Yat-Fung Shea, Angel On-Kei Chan, Leung-Wing Chu, Shui-Ching Lee, Chun-Yin Law, Chung-Him See, Kit-Ling Yiu, Patrick Ka-Chun Chiu
Autosomal dominant familial Alzheimer's disease accounts for 0.5% of all Alzheimer's disease. A familial Alzheimer's disease Chinese family, with 7 affected family members, underwent PSEN1 screening in 3 affected family members. A heterozygous novel missense mutation in the PSEN1 gene c.1156T>A, altering phenylalanine to isoleucine at codon 386, was identified. Because the change occurred in conserved domains of this gene and cosegregated with affected family members, this change may have a mutagenic and probably pathogenic effect...
February 2017: Neurobiology of Aging
https://www.readbyqxmd.com/read/27796927/an-in-vitro-study-of-the-antifungal-activity-of-trichoderma-virens-7b-and-a-profile-of-its-non-polar-antifungal-components-released-against-ganoderma-boninense
#17
Lee Pei Lee Angel, Mohd Termizi Yusof, Intan Safinar Ismail, Bonnie Tay Yen Ping, Intan Nur Ainni Mohamed Azni, Norman Hj Kamarudin, Shamala Sundram
Ganoderma boninense is the causal agent of a devastating disease affecting oil palm in Southeast Asian countries. Basal stem rot (BSR) disease slowly rots the base of palms, which radically reduces productive lifespan of this lucrative crop. Previous reports have indicated the successful use of Trichoderma as biological control agent (BCA) against G. boninense and isolate T. virens 7b was selected based on its initial screening. This study attempts to decipher the mechanisms responsible for the inhibition of G...
November 2016: Journal of Microbiology / the Microbiological Society of Korea
https://www.readbyqxmd.com/read/27793324/central-venous-parathyroid-hormone-monitoring-using-a-novel-specific-anatomic-method-accurately-predicts-cure-during-minimally-invasive-parathyroidectomy
#18
Courtney M Edwards, Jessica Folek, Samantha Dayawansa, Cara M Govednik, Courtney E Quinn, Benjamin R Sigmond, Cortney Y Lee, Melissa S Angel, John C Hendricks, Terry C Lairmore
BACKGROUND: Measurement of intraoperative parathyroid hormone (PTH) levels is an important adjunct to confirm biochemical cure during parathyroidectomy. The purpose of this study was to evaluate a simplified anatomic technique for PTH sampling from the central veins through the minimally invasive neck incision, and to compare the predictive accuracy of central and peripheral PTH values. METHODS: A specific anatomic method for central PTH sampling was employed in 48 patients...
December 2016: American Journal of Surgery
https://www.readbyqxmd.com/read/27785671/a-crosswalk-between-ucla-and-lower-extremity-activity-scales
#19
Hassan M K Ghomrawi, Yuo-Yu Lee, Christina Herrero, Amethia Joseph, Douglas Padgett, Geoffrey Westrich, Michael Parks, Stephen Lyman
BACKGROUND: The University of California, Los Angeles (UCLA) activity scale and the Lower Extremity Activity Scale (LEAS) are the two most-widely used and rigorously developed scales for assessing activity level in patients having joint replacement. However, the two scales are not convertible, and the level of correlation between the two is not clear. Creating a crosswalk between these scales; that is, a concordance table to convert scores from one scale to the other and vice versa, will help compare results from existing studies using either scale, and pool those results for meta-analyses...
October 26, 2016: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/27765500/loss-of-reduction-and-complications-of-coracoclavicular-ligament-reconstruction-with-autogenous-tendon-graft-in-acute-acromioclavicular-dislocations
#20
Nam Hong Choi, Seok Min Lim, Sang Young Lee, Tae Kang Lim
BACKGROUND: This study was conducted to report loss of reduction and complications after single-tunnel coracoclavicular (CC) ligament reconstruction with autogenous semitendinosus tendon graft for acute acromioclavicular (AC) joint dislocations. METHODS: This retrospective study included patients with acute, unstable AC dislocations (surgery within 6 weeks after trauma). We excluded patients with chronic injury and distal clavicle fractures with CC ligaments disruption...
October 17, 2016: Journal of Shoulder and Elbow Surgery
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