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https://www.readbyqxmd.com/read/28318302/isolated-subscapularis-repair-in-irreparable-posterosuperior-massive-rotator-cuff-tears-involving-the-subscapularis-tendon
#1
Sung-Jae Kim, Yun-Rak Choi, Min Jung, Won-Yong Lee, Yong-Min Chun
BACKGROUND: No previous study has examined whether isolated subscapularis tendon repair in irreparable posterosuperior massive rotator tears involving the subscapularis tendon in relatively young patients without arthritis can yield satisfactory outcomes. HYPOTHESIS: We hypothesized that this procedure would produce favorable outcomes in patients who might otherwise be candidates for reverse arthroplasty. STUDY DESIGN: Case series; Level of evidence, 4...
March 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28299310/corrigendum-fluidic-logic-used-in-a-systems-approach-to-enable-integrated-single-cell-functional-analysis
#2
Naveen Ramalingam, Brian Fowler, Lukasz Szpankowski, Anne A Leyrat, Kyle Hukari, Myo Thu Maung, Wiganda Yorza, Michael Norris, Chris Cesar, Joe Shuga, Michael L Gonzales, Chad D Sanada, Xiaohui Wang, Rudy Yeung, Win Hwang, Justin Axsom, Naga Sai Gopi Krishna Devaraju, Ninez Delos Angeles, Cassandra Greene, Ming-Fang Zhou, Eng-Seng Ong, Chang-Chee Poh, Marcos Lam, Henry Choi, Zaw Htoo, Leo Lee, Chee-Sing Chin, Zhong-Wei Shen, Chong T Lu, Ilona Holcomb, Aik Ooi, Craig Stolarczyk, Tony Shuga, Kenneth J Livak, Cate Larsen, Marc Unger, Jay A A West
[This corrects the article on p. 70 in vol. 4, PMID: 27709111.].
2017: Frontiers in Bioengineering and Biotechnology
https://www.readbyqxmd.com/read/28298061/arthroscopic-repair-of-anterosuperior-massive-rotator-cuff-tears
#3
Sung-Jae Kim, Yun-Rak Choi, Min Jung, Wonyong Lee, Yong-Min Chun
BACKGROUND: The purpose of this study was to investigate clinical outcomes and structural integrity after arthroscopic repair of anterosuperior massive rotator cuff tears (RCTs) and to compare clinical outcomes between healed and retear groups. HYPOTHESIS: The authors hypothesized that although both groups would exhibit improved clinical outcomes compared with their preoperative status, the healed group would have better clinical outcomes than the retear group, and in the retear group, the subscapularis retear subgroup would have inferior outcomes compared with the intact subscapularis repair subgroup...
February 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28296378/-type-i-chiari-malformation-associated-with-cerebellar-atrophy-case-report
#4
Luis Rafael Moscote-Salazar, Willem Guillermo Calderón-Miranda, Hernando Raphael Alvis-Miranda, Ángel Lee-Aguirre, Gabriel Alcalá-Cerra
Chiari malformation is characterized by caudal displacement of the cerebellar tonsils that penetrate into the spinal canal through the foramen magnum, achieving reach the atlas or axis. trunk and any drop of the fourth ventricle is observed. Typically is seen in young adults. In some cases scoliosis and Syringomyelic cavities may occur. The authors present (as far as they know) the first case in the literature with long term follow-up, of a caucasian woman with an unusual form of cerebellar atrophy and Chiari Type I malformation, suffering from weakness in his upper and lower extremities with rapidly progression...
March 2017: Revista Médica del Instituto Mexicano del Seguro Social
https://www.readbyqxmd.com/read/28264879/abcg1-regulates-pulmonary-surfactant-metabolism-in-mice-and-men
#5
Thomas Q de Aguiar Vallim, Elinor Lee, David J Merriott, Christopher N Goulbourne, Joan Cheng, Angela Cheng, Ayelet Gonen, Ryan M Allen, Elisa N D Palladino, David A Ford, Tisha Wang, Ángel Baldán, Elizabeth J Tarling
Idiopathic pulmonary alveolar proteinosis (PAP) is a rare lung disease characterized by accumulation of surfactant. Surfactant synthesis and secretion are restricted to epithelial type 2 pneumocytes (T2 cells). Clearance of surfactant is dependent upon T2 cells and macrophages. ATP Binding Cassette Transporter G1 (ABCG1) is highly expressed in both T2 cells and macrophages. ABCG1-deficient mice accumulate surfactant, lamellar body-loaded T2 cells, lipid-loaded macrophages, B-1 lymphocytes and immunoglobulins, clearly demonstrating ABCG1 has a critical role in pulmonary homeostasis...
March 6, 2017: Journal of Lipid Research
https://www.readbyqxmd.com/read/28264069/alcohol-and-tea-consumption-are-associated-with-asymptomatic-erosive-esophagitis-in-taiwanese-men
#6
Chung-Hsin Chang, Cheng-Pin Wu, Jung-Der Wang, Shou-Wu Lee, Chi-Sen Chang, Hong-Zen Yeh, Chung-Wang Ko, Han-Chung Lien
OBJECTIVE: Asymptomatic erosive esophagitis (AEE) is commonly found in men, and might be a risk factor of developing esophageal adenocarcinoma. We aimed to determine if specific dietary habits increase the risk of AEE in asymptomatic Taiwanese men. METHODS: We recruited male adults undergoing upper gastrointestinal endoscopy for health check. We excluded subjects with reflux symptoms, or taking anti-reflux medications or drugs that potentially impair lower esophageal sphincter function or cause mucosal injury...
2017: PloS One
https://www.readbyqxmd.com/read/28207884/correction-a-european-spectrum-of-pharmacogenomic-biomarkers-implications-for-clinical-pharmacogenomics
#7
Clint Mizzi, Eleni Dalabira, Judit Kumuthini, Nduna Dzimiri, Istvan Balogh, Nazli Başak, Ruwen Böhm, Joseph Borg, Paola Borgiani, Nada Bozina, Henrike Bruckmueller, Beata Burzynska, Angel Carracedo, Ingolf Cascorbi, Constantinos Deltas, Vita Dolzan, Anthony Fenech, Godfrey Grech, Vytautas Kasiulevicius, Ľudevít Kádaši, Vaidutis Kučinskas, Elza Khusnutdinova, Yiannis L Loukas, Milan Macek, Halyna Makukh, Ron Mathijssen, Konstantinos Mitropoulos, Christina Mitropoulou, Giuseppe Novelli, Ioanna Papantoni, Sonja Pavlovic, Giuseppe Saglio, Jadranka Sertić, Maja Stojiljkovic, Andrew P Stubbs, Alessio Squassina, Maria Torres, Marek Turnovec, Ron H van Schaik, Konstantinos Voskarides, Salma M Wakil, Anneke Werk, Maria Del Zompo, Branka Zukic, Theodora Katsila, Ming Ta Michael Lee, Alison Motsinger-Rief, Howard L Mc Leod, Peter J van der Spek, George P Patrinos
[This corrects the article DOI: 10.1371/journal.pone.0162866.].
2017: PloS One
https://www.readbyqxmd.com/read/28192647/a-double-blind-randomized-multicenter-clinical-trial-investigating-the-efficacy-and-safety-of-esomeprazole-single-therapy-versus-mosapride-and-esomeprazole-combined-therapy-in-patients-with-esophageal-reflux-disease
#8
Ju Yup Lee, Sung Kook Kim, Kwang Bum Cho, Kyung Sik Park, Joong Goo Kwon, Jin Tae Jung, Eun Young Kim, Byung Ik Jang, Si Hyung Lee
Background/Aims: We aimed to evaluate the efficacy and safety of combination therapy in erosive reflux disease (ERD) patients by comparing endoscopic healing rate according to the Los Angeles classification for esomeprazole alone and esomeprazole plus mosapride. Methods: A total of 116 ERD patients were randomized to receive esomeprazole 40 mg once daily plus mosapride 5 mg 3 times daily (E+M group), or esomeprazole plus placebo (E only group) for 8 weeks. Patients recorded gastroesophageal reflux disease (GERD) symptom questionnaire at week 4 and 8...
February 13, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28190644/what-are-normal-metal-ion-levels-after-total-hip-arthroplasty-a%C3%A2-serologic-analysis-of-four-bearing-surfaces
#9
Brian T Barlow, Philippe A Ortiz, John W Boles, Yuo-Yu Lee, Douglas E Padgett, Geoffrey H Westrich
BACKGROUND: The recent experiences with adverse local tissue reactions have highlighted the need to establish what are normal serum levels of cobalt (Co), chromium (Cr), and titanium (Ti) after hip arthroplasty. METHODS: Serum Co, Cr, and Ti levels were measured in 80 nonconsecutive patients with well-functioning unilateral total hip arthroplasty and compared among 4 bearing surfaces: ceramic-on-ceramic (CoC); ceramic-on-polyethylene (CoP); metal-on-polyethylene (MoP), and dual mobility (DM)...
December 3, 2016: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28138098/genetic-and-mechanistic-analyses-of-the-periplasmic-domain-of-the-enterohemorrhagic-e-coli-ehec-qsec-histidine-sensor-kinase
#10
Christopher T Parker, Regan Russell, Jacqueline W Njoroge, Angel G Jimenez, Ron Taussig, Vanessa Sperandio
The histidine sensor kinase (HK) QseC, senses autoinducer-3 (AI-3), and the adrenergic hormones epinephrine and norepinephrine. Upon sensing these signals, QseC acts through three response regulators (RRs) to regulate expression of virulence genes in enterohemorrhagic E. coli (EHEC). The QseB, QseF and KdpE RRs that are phosphorylated by QseC constitute a tripartite signaling cascade having different and overlapping targets, including flagella and motility, the type three secretion system encoded by the locus of enterocyte effacement (LEE), and Shiga toxin...
January 30, 2017: Journal of Bacteriology
https://www.readbyqxmd.com/read/28131682/clavicle-hook-plate-fixation-for-distal-third-clavicle-fracture-neer-type-ii-comparison-of-clinical-and-radiologic-outcomes-between-neer-types-iia-and-iib
#11
Wonyong Lee, Chong-Hyuk Choi, Yun-Rak Choi, Kyung-Han Lim, Yong-Min Chun
BACKGROUND: The purpose of this study was to investigate clinical and radiologic outcomes of clavicle hook plate fixation for distal-third clavicle fracture (Neer type II) and to compare the clinical and radiologic outcomes and complications between Neer type IIA and type IIB. METHODS: We retrospectively reviewed 35 patients who underwent open reduction and internal fixation with AO hook locking compression plate (LCP) for distal clavicle fracture, including 13 patients with Neer type IIA and 22 patients with type IIB...
January 26, 2017: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/28109809/potent-inhibition-of-monoamine-oxidase-a-by-decursin-from-angelica-gigas-nakai-and-by-wogonin-from-scutellaria-baicalensis-georgi
#12
Hyun Woo Lee, Hyung Won Ryu, Myung-Gyun Kang, Daeui Park, Hanna Lee, Heung Mook Shin, Sei-Ryang Oh, Hoon Kim
During the ongoing search for new monoamine oxidase (MAO) inhibitors, five coumarin derivatives and eight flavonoids were isolated from the roots of Angelica gigas Nakai and Scutellaria baicalensis Georgi, respectively. Of the phytochemicals, decursin (4) was found to potently and selectively inhibit human MAO-A (IC50=1.89μM). The IC50 value of 4 for MAO-A belonged to the lowest group in herbal sources and was similar to that of toloxatone (1.78μM), a marketed drug. Wogonin (11) effectively inhibited MAO-A and MAO-B (IC50=6...
April 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28102896/impact-of-pre-transplant-depression-on-outcomes-of-allogeneic-and-autologous-hematopoietic-stem-cell-transplantation
#13
Areej El-Jawahri, Yi-Bin Chen, Ruta Brazauskas, Naya He, Stephanie J Lee, Jennifer M Knight, Navneet Majhail, David Buchbinder, Raquel M Schears, Baldeep M Wirk, William A Wood, Ibrahim Ahmed, Mahmoud Aljurf, Jeff Szer, Sara M Beattie, Minoo Battiwalla, Christopher Dandoy, Miguel-Angel Diaz, Anita D'Souza, Cesar O Freytes, James Gajewski, Usama Gergis, Shahrukh K Hashmi, Ann Jakubowski, Rammurti T Kamble, Tamila Kindwall-Keller, Hilard M Lazarus, Adriana K Malone, David I Marks, Kenneth Meehan, Bipin N Savani, Richard F Olsson, David Rizzieri, Amir Steinberg, Dawn Speckhart, David Szwajcer, Helene Schoemans, Sachiko Seo, Celalettin Ustun, Yoshiko Atsuta, Jignesh Dalal, Carmem Sales-Bonfim, Nandita Khera, Theresa Hahn, Wael Saber
BACKGROUND: To evaluate the impact of depression before autologous and allogeneic hematopoietic cell transplantation (HCT) on clinical outcomes post-transplantation. METHODS: We analyzed data from the Center for International Blood and Marrow Transplant Research to compare outcomes after autologous (n = 3786) or allogeneic (n = 7433) HCT for adult patients with hematologic malignancies with an existing diagnosis of pre-HCT depression requiring treatment versus those without pre-HCT depression...
January 19, 2017: Cancer
https://www.readbyqxmd.com/read/28100251/consensus-guideline-for-the-diagnosis-and-treatment-of-aromatic-l-amino-acid-decarboxylase-aadc-deficiency
#14
REVIEW
Tessa Wassenberg, Marta Molero-Luis, Kathrin Jeltsch, Georg F Hoffmann, Birgit Assmann, Nenad Blau, Angeles Garcia-Cazorla, Rafael Artuch, Roser Pons, Toni S Pearson, Vincenco Leuzzi, Mario Mastrangelo, Phillip L Pearl, Wang Tso Lee, Manju A Kurian, Simon Heales, Lisa Flint, Marcel Verbeek, Michèl Willemsen, Thomas Opladen
Aromatic L-amino acid decarboxylase deficiency (AADCD) is a rare, autosomal recessive neurometabolic disorder that leads to a severe combined deficiency of serotonin, dopamine, norepinephrine and epinephrine. Onset is early in life, and key clinical symptoms are hypotonia, movement disorders (oculogyric crisis, dystonia, and hypokinesia), developmental delay, and autonomic symptoms.In this consensus guideline, representatives of the International Working Group on Neurotransmitter Related Disorders (iNTD) and patient representatives evaluated all available evidence for diagnosis and treatment of AADCD and made recommendations using SIGN and GRADE methodology...
January 18, 2017: Orphanet Journal of Rare Diseases
https://www.readbyqxmd.com/read/28066820/hiv-care-providers-attitudes-regarding-mobile-phone-applications-and-web-based-dashboards-to-support-patient-self-management-and-care-coordination-results-from-a-qualitative-feasibility-study
#15
Dallas Swendeman, Shu Farmer, Deborah Mindry, Sung-Jae Lee, Melissa Medich
In-depth qualitative interviews were conducted with healthcare providers (HCPs) from five HIV medical care coordination teams in a large Los Angeles County HIV clinic, including physicians, nurses, and psychosocial services providers. HCPs reported on the potential utility, acceptability, and barriers for patient self-monitoring and notifications via mobile phones, and web-based dashboards for HCPs. Potential benefits included: 1) enhancing patient engagement, motivation, adherence, and self-management; and 2) improving provider-patient relationships and HCP care coordination...
October 2016: Journal of HIV and AIDS
https://www.readbyqxmd.com/read/28045615/cost-comparison-of-genetic-testing-strategies-in-women-with-epithelial-ovarian-cancer
#16
Jonathan R Foote, Micael Lopez-Acevedo, Adam H Buchanan, Angeles Alvarez Secord, Paula S Lee, Cynthia Fountain, Evan R Myers, David E Cohn, Shelby D Reed, Laura J Havrilesky
PURPOSE: The advent of multigene panels has increased genetic testing options for women with epithelial ovarian cancer (EOC). We designed a decision model to compare costs and probabilities of identifying a deleterious mutation or variant of uncertain significance (VUS) using different genetic testing strategies. METHODS: A decision model was developed to compare costs and outcomes of two testing strategies for women with EOC: multigene testing (MGT) versus single-gene testing for BRCA1/2...
January 3, 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/28032315/erratum-to-personal-identity-development-in-hispanic-immigrant-adolescents-links-with-positive-psychosocial-functioning-depressive-symptoms-and-externalizing-problems
#17
Seth J Schwartz, Jennifer B Unger, Alan Meca, Elma I Lorenzo-Blanco, Lourdes Baezconde-Garbanati, Miguel Ángel Cano, Brandy Piña-Watson, José Szapocznik, Byron L Zamboanga, David Córdova, Andrea J Romero, Tae Kyoung Lee, Daniel W Soto, Juan A Villamar, Karina M Lizzi, Sabrina E Des Rosiers, Monica Pattarroyo
No abstract text is available yet for this article.
December 28, 2016: Journal of Youth and Adolescence
https://www.readbyqxmd.com/read/27969754/tct-404-absorb-bioresorbable-vascular-scaffold-vs-everolimus-eluting-metallic-stent-in-st-segment-elevation-myocardial-infarction-bvs-examination-study-2-year-results-from-a-propensity-score-matched-comparison
#18
Salvatore Brugaletta, Tommaso Gori, Adrian Low, Petr Tousek, Eduardo Pinar Bermudez, Josep Gomez Lara, Luis Ortega-Paz, Eberhard Schulz, Mark Chan, Viktor Kocka, Jose Hurtado, Joan Antoni Gomez-Hospital, Thomas Muenzel, Chi-Hang Lee, Angel Cequier, Mariano Valdes, Petr Widimsky, Patrick Serruys, Manel Sabate
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27943007/the-impact-of-doctor-patient-communication-on-patients-perceptions-of-their-risk-of-breast-cancer-recurrence
#19
Nancy K Janz, Yun Li, Brian J Zikmund-Fisher, Reshma Jagsi, Allison W Kurian, Lawrence C An, M Chandler McLeod, Kamaria L Lee, Steven J Katz, Sarah T Hawley
PURPOSE: Doctor-patient communication is the primary way for women diagnosed with breast cancer to learn about their risk of distant recurrence. Yet little is known about how doctors approach these discussions. METHODS: A weighted random sample of newly diagnosed early-stage breast cancer patients identified through SEER registries of Los Angeles and Georgia (2013-2015) was sent surveys about ~2 months after surgery (Phase 2, N = 3930, RR 68%). We assessed patient perceptions of doctor communication of risk of recurrence (i...
February 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/27934961/minimum-electric-field-exposure-for-seizure-induction-with-electroconvulsive-therapy-and-magnetic-seizure-therapy
#20
Won Hee Lee, Sarah H Lisanby, Andrew F Laine, Angel V Peterchev
Lowering and individualizing the current amplitude in electroconvulsive therapy (ECT) has been proposed as a means to produce stimulation closer to the neural activation threshold and more focal seizure induction, which could potentially reduce cognitive side effects. However, the effect of current amplitude on the electric field (E-field) in the brain has not been previously linked to the current amplitude threshold for seizure induction. We coupled MRI-based E-field models with amplitude titrations of motor threshold (MT) and seizure threshold (ST) in four nonhuman primates (NHPs) to determine the strength, distribution, and focality of stimulation in the brain for four ECT electrode configurations (bilateral, bifrontal, right-unilateral, and frontomedial) and magnetic seizure therapy (MST) with cap coil on vertex...
December 9, 2016: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
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