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Pediatric hypertension

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https://www.readbyqxmd.com/read/29131049/changing-characteristics-of-obese-children-and-adolescents-entering-pediatric-lifestyle-intervention-programs-in-germany-over-the-last-11-years-an-adiposity-patients-registry-multicenter-analysis-of-65-453-children-and-adolescents
#1
Barbara Bohn, Susanna Wiegand, Wieland Kiess, Thomas Reinehr, Rainer Stachow, Johannes Oepen, Helmut Langhof, Thomas Hermann, Kurt Widhalm, Martin Wabitsch, Ines Gellhaus, Reinhard Holl
OBJECTIVE: To examine whether characteristics of children and adolescents who start lifestyle intervention (LI) for obesity in Germany changed over the last decade. METHODS: 65,453 subjects (<21 years) from the APV database (Adiposity Patients Registry) with a BMI ≥ 90th percentile were included (years 2005-2015). Logistic regression models (confounders: age, sex, migration background) were created for overweight, obesity, extreme obesity, and obesity-related comorbidities...
2017: Obesity Facts
https://www.readbyqxmd.com/read/29129352/pediatric-cardiovascular-morbidity-of-the-early-term-newborn
#2
Gil Gutvirtz, Tamar Wainstock, Eyal Sheiner, Daniella Landau, Asnat Walfisch
OBJECTIVE: To determine whether early term delivery (at 37(0/7)-38(6/7) weeks of gestation) is associated with long-term pediatric cardiovascular morbidity of the offspring. STUDY DESIGN: A population-based cohort analysis was performed including all term deliveries occurring between 1991 and 2014 at a single tertiary medical center. Gestational age at delivery was subdivided into early term (37(0/7)-38(6/7)), full term (39(0/7)-40(6/7)), late term (41(0/7)-41(6/7)) and post term (≥42(0/7)) delivery...
November 9, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/29119033/the-utility-of-mri-in-the-diagnosis-of-takayasu-arteritis
#3
Marian Gaballah, Rachelle Goldfisher, John B Amodio
Takayasu Arteritis (TA) is an inflammatory disorder involving the thoracoabdominal aorta and its branches and the pulmonary arteries, with eventual vascular stenosis, occlusion, or aneurysm formation. Conventional angiography has been the reference imaging standard for diagnosis of TA. The purpose of this case report is to demonstrate the utility of MR imaging and MR angiography in the diagnosis of Takayasu Arteritis in a pediatric patient. The patient is a 15-year-old female patient presenting with anemia, hypertension, and acute kidney injury...
2017: Case Reports in Pediatrics
https://www.readbyqxmd.com/read/29117866/ambulatory-systolic-blood-pressure-and-obesity-are-independently-associated-with-left-ventricular-hypertrophic-remodeling-in-children
#4
Linyuan Jing, Christopher D Nevius, Cassi M Friday, Jonathan D Suever, Arichanah Pulenthiran, Abba Mejia-Spiegeler, H Lester Kirchner, William J Cochran, Gregory J Wehner, Aftab S Chishti, Christopher M Haggerty, Brandon K Fornwalt
BACKGROUND: Children with obesity have hypertrophic cardiac remodeling. Hypertension is common in pediatric obesity, and may independently contribute to hypertrophy. We hypothesized that both the degree of obesity and ambulatory blood pressure (ABP) would independently associate with measures of hypertrophic cardiac remodeling in children. METHODS: Children, aged 8-17 years, prospectively underwent cardiovascular magnetic resonance (CMR) and ABP monitoring. Left ventricular (LV) mass indexed to height(2...
November 9, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/29117624/the-role-of-lipids-in-the-pathogenesis-of-metabolic-syndrome-in-adolescents
#5
Shahnaz Taghizadeh, Mohammad Alizadeh
The increasing prevalence of childhood obesity is a driving force behind the increase in adolescent's metabolic syndrome (MetS). Although there is no clear consensus about the pediatric definition for MetS, this syndrome is becoming very common among adolescents. It is characterized by insulin resistance (IR), dyslipidemia, abdominal obesity and hypertension, and is associated with a high risk of type 2 diabetes mellitus and CVD in adulthood. Due to the increasing prevalence of obesity, there is strong incentive to reduce the impact of the adverse health effects associated with MetS...
November 8, 2017: Experimental and Clinical Endocrinology & Diabetes
https://www.readbyqxmd.com/read/29097019/secondary-intracranial-hypertension-in-pediatric-patients-with-leukemia
#6
Miguel Ángel Fernández-García, Verónica Cantarín-Extremera, Maitane Andión-Catalán, Anna Duat-Rodríguez, Saioa Jiménez-Echevarría, Ignacio Bermejo-Arnedo, Montesclaros Hortigüela-Saeta, Saray Rekarte-García, Lara Babín-López, David Ruano Domínguez
BACKGROUND: We investigated the clinical characteristics of a pediatric population with hemato-oncological disease and intracranial hypertension, analyze the therapeutic response and outcome, and compare its characteristics with respect to a control group with idiopathic intracranial hypertension. METHODS: We retrospectively analyzed patients with hemato-oncological disease and secondary intracranial hypertension in our center during the past five years. We compared these individuals with a historical cohort with idiopathic intracranial hypertension from our institution (control group)...
September 1, 2017: Pediatric Neurology
https://www.readbyqxmd.com/read/29084001/assessing-the-borderline-ventricle-in-a-term-infant-combining-imaging-and-physiology-to-establish-the-right-course
#7
Meryl S Cohen
PURPOSE OF REVIEW: The purpose of this review is to describe the challenges associated with the diagnosis and treatment of children with borderline ventricles. A borderline ventricle is one in which there is concern that it will not be able to support its circulation. If a biventricular repair is attempted and fails, outcome is often poor. Thus, this early decision is important. RECENT FINDINGS: For the borderline right ventricle, options to add an additional source of pulmonary blood flow make the surgical strategy a bit more flexible than for patients with a borderline left ventricle...
October 27, 2017: Current Opinion in Cardiology
https://www.readbyqxmd.com/read/29081363/diagnostic-criteria-in-pediatric-intracranial-hypertension
#8
Hilliary E Inger, David L Rogers, Mary Lou McGregor, Shawn C Aylward, Rachel E Reem
BACKGROUND: The modified Dandy criteria and the newer diagnostic criteria for pseudotumor cerebri syndrome (PTCS) are both used to diagnose intracranial hypertension (IH). In comparison to the modified Dandy criteria, the PTCS criteria stratify the IH diagnosis into definite, probable, and suggested categories, exclude clinical symptoms, and use radiologic evidence for diagnosis. There is a lack of consensus on which criteria should be used in the pediatric population. The purpose of this study was to compare the diagnostic criteria for PTCS to the modified Dandy criteria and to identify limitations within both sets of criteria...
November 8, 2017: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/29078111/markers-of-coagulation-activation-inflammation-and-fibrinolysis-as-predictors-of-poor-outcomes-after-pediatric-venous-thromboembolism-a-systematic-review-and-meta-analysis
#9
REVIEW
Ayesha Zia, Joy Russell, Ravi Sarode, Surendranath R Veeram, Shellie Josephs, Kendra Malone, Song Zhang, Janna Journeycake
BACKGROUND: Sequelae of venous thromboembolism (VTE) in children include recurrence, development of post thrombotic syndrome (PTS) when venous return from a limb is affected and chronic thromboembolic pulmonary hypertension (CTEPH) after pulmonary embolism. Identification of laboratory-based risk factors may be useful for individualized risk assessment for VTE sequelae. Coagulation activation and inflammation may contribute to their pathophysiology. We performed a systematic review to investigate the association between biomarkers of coagulation activation, inflammation and fibrinolysis and adverse VTE outcomes in children and young adults...
October 7, 2017: Thrombosis Research
https://www.readbyqxmd.com/read/29076654/the-respiratory-system-in-pediatric-chronic-heart-disease
#10
REVIEW
Sotiria C Apostolopoulou
Cardiovascular disease in the pediatric population closely affects the respiratory system inducing water retention in the lungs and pulmonary edema, airway compression by cardiovascular structures, restrictive pulmonary physiology as a result of hemodynamic changes and surgical repair, susceptibility to respiratory infections, development of pulmonary hypertension, thrombosis, or hemorrhage. Chronic heart failure and congenital heart disease are characterized by various respiratory manifestations and symptoms mimicking lung disease, which are frequently difficult to diagnose and treat...
October 27, 2017: Pediatric Pulmonology
https://www.readbyqxmd.com/read/29076289/orthotopic-liver-transplantation-for-sensenbrenner-syndrome
#11
Ruth Linda Ackah, Dor Yoeli, Michael Kueht, Nhu Thao Nguyen Galván, Ronald Timothy Cotton, Abbas Rana, Christine Ann O'Mahony, John Alan Goss
Sensenbrenner syndrome, or cranioectodermal dysplasia, is a rare heterogeneic autosomal recessive disorder, affecting ~1 of 1 000 000 live births. The syndrome usually manifests within the first year of life and can present with progressive liver and renal involvement. For all Sensenbrenner patients, renal and liver diseases are the main contributors of morbidity and mortality. In this report, we present the case of a 7-year-old boy with congenital liver disease progressing to liver failure secondary to Sensenbrenner syndrome...
October 26, 2017: Pediatric Transplantation
https://www.readbyqxmd.com/read/29075864/the-use-of-electronic-health-records-to-identify-children-with-elevated-blood-pressure-and-hypertension
#12
REVIEW
Michael G Semanik
Elevated blood pressures often go unrecognized in pediatric patients, potentially putting children and adolescents at risk for the sequelae of untreated hypertension. This may be partially due to the complexity involved in diagnosing elevated pediatric blood pressures, which demands a high cognitive workload from providers. Tools built into electronic health records have the potential to alleviate this workload, and studies investigating these tools confirm they show promise in improving elevated blood pressure recognition...
October 26, 2017: Current Hypertension Reports
https://www.readbyqxmd.com/read/29072231/evaluation-of-drug-utilization-pattern-for-patients-of-bronchial-asthma-in-a-government-hospital-of-saudi-arabia
#13
M M Rafeeq, Has Murad
BACKGROUND: Bronchial asthma is a social and economic healthcare burden. Drug utilization studies are important tools to assess current prescription practices against standard guidelines and help in rationalizing the management. MATERIALS AND METHODS: This retrospective cross-sectional study was designed to evaluate the pattern of drug utilization in bronchial asthma patients in a government hospital of Saudi Arabia. Retrospective prescribing information of patients of all ages and both sexes diagnosed with bronchial asthma being treated with at least one of the anti-asthmatic medications was utilized...
September 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/29071783/age-is-not-a-good-predictor-of-irreversibility-of-pulmonary-hypertension-in-congenital-cardiac-malformations-with-left-to-right-shunt
#14
Amir-Reza Hosseinpour, Marie-Hélène Perez, David Longchamp, Jacques Cotting, Nicole Sekarski, Michel Hurni, René Prêtre, Stefano Di Bernardo
OBJECTIVE: Congenital cardiac malformations with high pulmonary blood flow and pressure due to left-to-right shunts are usually repaired in early infancy for both the benefits of early relief of heart failure and the fear that the concomitant pulmonary hypertension may become irreversible unless these defects are corrected at an early age. Age, however, has been a poor predictor of irreversibility of pulmonary hypertension in our experience, which is presented here. DESIGN: A retrospective observational study...
October 25, 2017: Congenital Heart Disease
https://www.readbyqxmd.com/read/29071489/ambulatory-blood-pressure-monitoring-in-children-and-adolescents-a-review-of-recent-literature-and-new-guidelines
#15
REVIEW
Ian Macumber
PURPOSE OF REVIEW: This is a review of ambulatory blood pressure monitoring (ABPM) use in pediatrics, focusing on research published in the last 3 to 4 years. RECENT FINDINGS: Recent data has shown that ABPM is more strongly associated with end-organ damage than casual BP, and that obesity and secondary causes of hypertension are strongly associated with nocturnal hypertension. There is evidence that ABPM is useful in management of a larger variety of diagnoses than previously thought...
October 25, 2017: Current Hypertension Reports
https://www.readbyqxmd.com/read/29071163/resolution-of-periodic-breathing-in-a-child-with-idiopathic-pulmonary-arterial-hypertension
#16
Saadoun Bin-Hasan, Abdullah Khayat, Tilman Humpl, Janette T Reyes, Suhail Al-Saleh
Central sleep apnea (CSA) and periodic breathing are unusual findings described in pediatric patients with congestive heart failure. However, CSA has not been reported in children with pulmonary hypertension. We hereby report on a 10-year-old girl with idiopathic pulmonary arterial hypertension who had frequent central events in a periodic breathing fashion seen in her polysomnography, which was normalized following medical treatment leading to improvement of the pulmonary pressures.
2017: Case Reports in Pediatrics
https://www.readbyqxmd.com/read/29070828/high-blood-pressure-and-its-relationship-to-adiposity-in-a-school-aged-population-body-mass-index-vs-waist-circumference
#17
William Rodrigues Tebar, Raphael Mendes Ritti-Dias, Breno Quintella Farah, Edner Fernando Zanuto, Luiz Carlos Marques Vanderlei, Diego Giulliano Destro Christofaro
High blood pressure (HBP) is a major concern in pediatric populations. Adiposity is highly related to HBP in youths; however, whether body mass index (BMI) or waist circumference (WC) is more strongly associated with HBP in this population is unclear. This cross-sectional study, involving schoolchildren between 10 and 17 years of age from public and private schools, assessed direct measurements of BMI, WC and blood pressure. The socioeconomic level, sedentary behavior, physical activity, alcohol consumption and smoking history were obtained through a questionnaire...
October 26, 2017: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/29064445/pediatric-perioperative-pulmonary-arterial-hypertension-a-case-based-primer
#18
REVIEW
Shilpa Shah, Jacqueline R Szmuszkovicz
The perioperative period is an extremely tenuous time for the pediatric patient with pulmonary arterial hypertension. This article will discuss a multidisciplinary approach to preoperative planning, the importance of early identification of pulmonary hypertensive crises, and practical strategies for postoperative management for this unique group of children.
October 24, 2017: Children
https://www.readbyqxmd.com/read/29055603/end-stage-renal-disease-after-pediatric-heart-transplantation-a-25-year-national-cohort-study
#19
Swati Choudhry, Vikas R Dharnidharka, Chesney D Castleberry, Charles W Goss, Kathleen E Simpson, Kenneth B Schechtman, Charles E Canter
BACKGROUND: End-stage renal disease (ESRD), defined as the need for chronic dialysis and/or kidney transplantation (KTx), is a known complication after heart transplant (HTx). However, factors associated with ESRD are not well elucidated. The objectives of this study were to determine the prevalence, risk factors, and outcomes associated with ESRD after pediatric HTx. METHODS: Scientific Registry of Transplant Recipients data were linked, using direct identifiers, to the United States Renal Data System to identify patients (aged ≤ 18 years) who underwent primary HTx between 1989 and 2013...
October 2, 2017: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/29055500/long-term-systemic-corticosteroid-exposure-a-systematic-literature-review
#20
REVIEW
J Bradford Rice, Alan G White, Lauren M Scarpati, George Wan, Winnie W Nelson
PURPOSE: While corticosteroids are relatively inexpensive and commonly used as treatment for a variety of conditions, long-term use is known to be associated with certain toxicities. Prior systematic reviews have revealed an increased risk for costly adverse events (AEs), including bone fracture, infection, and gastrointestinal bleeding. The objective of this study was to conduct a systematic literature review of recent publications on the burden of long-term corticosteroid exposure, specifically, to summarize the AEs and economic impact of long-term corticosteroid use and to reveal data gaps for additional research...
October 18, 2017: Clinical Therapeutics
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