keyword
MENU ▼
Read by QxMD icon Read
search

Infective risk

keyword
https://www.readbyqxmd.com/read/27906042/what-is-the-impact-of-biologic-therapies-on-common-co-morbidities-in-patients-with-rheumatoid-arthritis
#1
REVIEW
Jenny Humphreys, Kimme Hyrich, Deborah Symmons
Biologic therapies have revolutionised disease control in patients with rheumatoid arthritis (RA). Theoretically, they have the potential to influence co-morbid disease associated with RA through better control of systemic inflammation. Conversely, co-morbidity may occur as an adverse effect of the drugs. The latest evidence from observational data shows an increased risk of infection in the first 6 months of treatment with tumour necrosis factor inhibitor (TNFi) therapies and potentially other biologic therapies...
December 1, 2016: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/27906027/antiretroviral-treatment-regardless-of-cd4-count-the-universal-answer-to-a-contextual-question
#2
REVIEW
Serge P Eholié, Anani Badje, Gérard M Kouame, Jean-Baptiste N'takpe, Raoul Moh, Christine Danel, Xavier Anglaret
After a period where it was recommended to start antiretroviral therapy (ART) early, the CD4 threshold for treating asymptomatic adults dropped to 200/mm(3) at the beginning of the 2000s. This was mostly due to a great prudence with regards to drug toxicity. The ART-start CD4 threshold in most international guidelines was then raised to 350/mm(3) in 2006-2009 and to 500/mm(3) in 2009-2013. Between 2012 and 2015, international guidelines went the last step further and recommended treating all HIV-infected adults regardless of their CD4 count...
July 26, 2016: AIDS Research and Therapy
https://www.readbyqxmd.com/read/27906018/hiv-sero-discordance-among-married-hiv-patients-initiating-anti-retroviral-therapy-in-northern-vietnam
#3
Vu Van Tam, Do Duy Cuong, Tobias Alfven, Ho Dang Phuc, Nguyen Thi Kim Chuc, Nguyen Phuong Hoa, Vinod Diwan, Mattias Larsson
BACKGROUND: In many countries in Asia, the HIV epidemic is in a concentrated phase, with high prevalence in certain risk groups, such as men who inject drugs. There is also a rapid increase of HIV among women. The latter might be due to high levels of sero-discordant couples and increasing transmission from male to female partners over time. METHODS: All adult married patients initiating antiretroviral treatment at four out-patient clinics in Quang Ninh province in north-eastern Vietnam between 2007 and 2009 were asked to participate in the study...
November 15, 2016: AIDS Research and Therapy
https://www.readbyqxmd.com/read/27906008/sero-prevalence-of-hbv-and-associated-risk-factors-among-hiv-positive-individuals-attending-art-clinic-at-mekelle-hospital-tigray-northern-ethiopia
#4
Letebrhan Weldemhret, Tsehaye Asmelash, Rashmi Belodu, Dawit Gebreegziabiher
BACKGROUND: Because of the shared mean of transmission, hepatitis B virus (HBV) is one of an important cause of co-morbidity and mortality in peoples living with HIV/AIDS. Hence, the aim of this study was to determine the sero-prevalence of HBV infection and associated risk factors in HIV/AIDS positive individuals attending ART clinic at Mekelle hospital, Mekelle, Northern Ethiopia. METHODS: A cross sectional study was conducted from August to October 2014 in HIV/AIDS positive adult individuals...
February 4, 2016: AIDS Research and Therapy
https://www.readbyqxmd.com/read/27906007/what-happens-to-cardiovascular-system-behind-the-undetectable-level-of-hiv-viremia
#5
REVIEW
Gabriella d'Ettorre, Giancarlo Ceccarelli, Paolo Pavone, Pietro Vittozzi, Gabriella De Girolamo, Ivan Schietroma, Sara Serafino, Noemi Giustini, Vincenzo Vullo
Despite the combined antiretroviral therapy has improved the length and quality of life of HIV infected patients, the survival of these patients is always decreased compared with the general population. This is the consequence of non-infectious illnesses including cardio vascular diseases. In fact large studies have indicated an increased risk of coronary atherosclerotic disease, myocardial infarction even in HIV patients on cART. In HIV infected patients several factors may contribute to the pathogenesis of cardiovascular problems: life-style, metabolic parameters, genetic predisposition, viral factors, immune activation, chronic inflammation and side effects of antiretroviral therapy...
April 27, 2016: AIDS Research and Therapy
https://www.readbyqxmd.com/read/27906006/integrated-therapy-for-hiv-and-tuberculosis
#6
REVIEW
Weerawat Manosuthi, Surasak Wiboonchutikul, Somnuek Sungkanuparph
Tuberculosis (TB) has been the most common opportunistic infection and cause of mortality among HIV-infected patients, especially in resource-limited countries. Clinical manifestations of TB vary and depend on the degree of immunodeficiency. Sputum microscopy and culture with drug-susceptibility testing are recommended as a standard method for diagnosing active TB. TB-related mortality in HIV-infected patients is high especially during the first few months of treatment. Integrated therapy of both HIV and TB is feasible and efficient to control the diseases and yield better survival...
May 12, 2016: AIDS Research and Therapy
https://www.readbyqxmd.com/read/27906002/hiv-1-genetic-diversity-and-its-distribution-characteristics-among-newly-diagnosed-hiv-1-individuals-in-hebei-province-china
#7
Xinli Lu, Cuiying Zhao, Wei Wang, Chenxi Nie, Yuqi Zhang, Hongru Zhao, Suliang Chen, Ze Cui
BACKGROUND: Since the first HIV-1 case in 1989, Hebei province has presented a clearly rising trend of HIV-1 prevalence, and HIV-1 genetic diversity has become the vital barrier to HIV prevention and control in this area. To obtain detailed information of HIV-1 spread in different populations and in different areas of Hebei, a cross-sectional HIV-1 molecular epidemiological investigation was performed across the province. METHODS: Blood samples of 154 newly diagnosed HIV-1 individuals were collected from ten prefectures in Hebei using stratified sampling...
January 19, 2016: AIDS Research and Therapy
https://www.readbyqxmd.com/read/27905998/sexually-transmitted-infections-and-pre-exposure-prophylaxis-challenges-and-opportunities-among-men-who-have-sex-with-men-in-the-us
#8
REVIEW
Hyman M Scott, Jeffrey D Klausner
Pre-Exposure Prophylaxis (PrEP) has shown high efficacy in preventing human immunodeficiency virus (HIV) infection among men who have sex with men (MSM) in several large clinical trials, and more recently in "real world" reports of clinical implementation and a PrEP demonstration project. Those studies also demonstrated high bacterial sexually transmitted infection (STI) incidence and raised the discussion of how PrEP may impact STI control efforts, especially in the setting of increasing Neisseria gonorrhoeae antimicrobial resistance and the increase in syphilis cases among MSM...
January 19, 2016: AIDS Research and Therapy
https://www.readbyqxmd.com/read/27905986/predictors-of-perceived-male-partner-concurrency-among-women-at-risk-for-hiv-and-sti-acquisition-in-durban-south-africa
#9
Zakir Gaffoor, Handan Wand, Renée A Street, Nathlee Abbai, Gita Ramjee
BACKGROUND: Women in sub-Saharan Africa continue to be at greater risk for HIV acquisition than men. Concurrency, viz. multiple sexual partnerships that overlap over time, has been studied as a possible risk factor for HIV transmission. The aim of this study was to identify predictors of perceived male partner concurrency among sexually active, HIV negative women. METHODS: Socio-demographic and behavioural data from women enrolled in a biomedical HIV prevention clinical trial were assessed in relation to perceived male partner concurrency using the Chi squared test...
March 8, 2016: AIDS Research and Therapy
https://www.readbyqxmd.com/read/27905979/diabetes-incidence-and-projections-from-prevalence-surveys-in-fiji
#10
Stephen Morrell, Sophia Lin, Isimeli Tukana, Christine Linhart, Richard Taylor, Penina Vatucawaqa, Dianna J Magliano, Paul Zimmet
BACKGROUND: Type 2 diabetes mellitus (T2DM) incidence is traditionally derived from cohort studies that are not always feasible, representative, or available. The present study estimates T2DM incidence in Fijian adults from T2DM prevalence estimates assembled from surveys of 25-64 year old adults conducted over 30 years (n = 14,288). METHODS: T2DM prevalence by five-year age group from five population-based risk factor surveys conducted over 1980-2011 were variously adjusted for urban-rural residency, ethnicity, and sex to previous censuses (1976, 1986, 1996, 2009) to improve representativeness...
November 25, 2016: Population Health Metrics
https://www.readbyqxmd.com/read/27905971/trends-causes-and-risk-factors-of-mortality-among-children-under-5-in-ethiopia-1990-2013-findings-from-the-global-burden-of-disease-study-2013
#11
Amare Deribew, Gizachew Assefa Tessema, Kebede Deribe, Yohannes Adama Melaku, Yihunie Lakew, Azmeraw T Amare, Semaw F Abera, Mesoud Mohammed, Abiy Hiruye, Efrem Teklay, Awoke Misganaw, Nicholas Kassebaum
BACKGROUND: Ethiopia has made remarkable progress in reducing child mortality over the last two decades. However, the under-5 mortality rate in Ethiopia is still higher than the under-5 mortality rates of several low- and middle-income countries (LMIC). On the other hand, the patterns and causes of child mortality have not been well investigated in Ethiopia. The objective of this study was to investigate the mortality trend, causes of death, and risk factors among children under 5 in Ethiopia during 1990-2013...
November 14, 2016: Population Health Metrics
https://www.readbyqxmd.com/read/27905934/estimation-of-country-specific-and-global-prevalence-of-male-circumcision
#12
Brian J Morris, Richard G Wamai, Esther B Henebeng, Aaron Ar Tobian, Jeffrey D Klausner, Joya Banerjee, Catherine A Hankins
BACKGROUND: Male circumcision (MC) status and genital infection risk are interlinked and MC is now part of HIV prevention programs worldwide. Current MC prevalence is not known for all countries globally. Our aim was to provide estimates for country-specific and global MC prevalence. METHODS: MC prevalence data were obtained by searches in PubMed, Demographic and Health Surveys, AIDS Indicator Surveys, and Behavioural Surveillance Surveys. Male age was ≥15 years in most surveys...
March 1, 2016: Population Health Metrics
https://www.readbyqxmd.com/read/27905913/sera-from-severe-trauma-patients-with-pneumonia-and-without-infectious-complications-have-differential-effects-on-neutrophil-biology
#13
B Relja, R Taraki, M P J Teuben, K Mörs, N Wagner, S Wutzler, F Hildebrand, M Perl, I Marzi
BACKGROUND: Major trauma patients (TP) developing imbalanced immune response are at high risk for infectious post-injury complications including pneumonia. Neutrophils play a central role in the host defense against bacteria and thereby pathogenesis of infections. While there are numerous studies about neutrophil function after trauma, data about their biology in patients who suffer from pneumonia following trauma are sparse. Here, we studied the effect of serum isolated from patients who do and do not develop infection (inf...
December 1, 2016: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/27905841/cell-delivered-entry-inhibitors-for-hiv-1-ccr5-downregulation-and-blocking-virus-membrane-fusion-in-defending-the-host-cell-population
#14
Geoff Symonds, Jeffrey S Bartlett, Hans-Peter Kiem, Marlene Tsie, Louis Breton
HIV-1 infection requires the presence of the CD4 receptor on the target cell surface and a coreceptor, predominantly CC-chemokine receptor 5 (CCR5). It has been shown that individuals who are homozygous for a defective CCR5 gene are protected from HIV-1 infection. A novel self-inactivating lentiviral vector LVsh5/C46 (Cal-1) has been engineered to block HIV-1 infection with two viral entry inhibitors, conferring resistance to HIV-1 infection from both CCR5 and CXCR4 tropic strains. Cal-1 encodes a short hairpin RNA (sh5) to downregulate CCR5 and C46, an HIV-1 fusion inhibitor...
December 2016: AIDS Patient Care and STDs
https://www.readbyqxmd.com/read/27905840/combining-cell-and-gene-therapy-in-an-effort-to-eradicate-hiv
#15
Thor A Wagner
More than 30 million people are infected with HIV, and HIV remains the fifth leading cause of disability-adjusted life years worldwide. Antiretroviral therapy (ART) dramatically decreases mortality rate, but there are side effects, long-term toxicities, expenses, stigmas, and inconveniences associated with chronic treatment, and HIV-infected individuals on ART have an increased risk of malignancies, cardiovascular disease, neurologic disease, and shortened life expectancy. Therefore, a cure for HIV remains an important goal...
December 2016: AIDS Patient Care and STDs
https://www.readbyqxmd.com/read/27905672/oral-astragalus-huang-qi-for-preventing-frequent-episodes-of-acute-respiratory-tract-infection-in-children
#16
REVIEW
Guobin Su, Xiankun Chen, Zhuangzhu Liu, Lihong Yang, La Zhang, Cecilia Stålsby Lundborg, Zehuai Wen, Xinfeng Guo, Xindong Qin, Jueyao Liang, Xusheng Liu
BACKGROUND: Acute respiratory tract infections (ARTIs) are common in children and can involve both upper and lower airways. Many children experience frequent ARTI episodes or recurrent respiratory tract infections (RRTIs) in early life, which creates challenges for paediatricians, primary care physicians, parents and carers of children.In China, Astragalus (Huang qi), alone or in combination with other herbs, is used by Traditional Chinese Medicine (TCM) practitioners in the form of a water extract, to reduce the risk of ARTIs; it is believed to stimulate the immune system...
December 1, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27905665/multiple-paternity-in-a-wild-population-of-armadillidium-vulgare-influence-of-infection-with-wolbachia
#17
V Valette, S Durand, N Bech, F Grandjean, S Beltran-Bech
Female multiple mating has been extensively studied to understand how nonobvious benefits, generally thought to be of genetic nature, could overcome heavy costs such as an increased risk of infection during mating. However, the impact of infection itself on multiple mating has rarely been addressed. The interaction between the bacterium Wolbachia and its terrestrial crustacean host, Armadillidium vulgare, is a relevant model to investigate this question. In this association, Wolbachia is able to turn genetic males into functional females (i...
November 4, 2016: Journal of Evolutionary Biology
https://www.readbyqxmd.com/read/27905650/-aseptic-techniques-for-minor-surgical-procedures
#18
Marcela Concha-Rogazy, Catalina Andrighetti-Ferrada, Maximiliano Curi-Tuma
Aseptic techniques are those practices designed to reduce the risk of surgical site infection (SSI), defined as such, all those that occur within the first 30 days of the procedure. While the patient’s risk of developing an SSI in dermatologic surgery is low since many of the procedures are considered sterile, there are different factors associated with an increased or decreased risk of developing SSI. The characteristics of the surgical wound (such as involving infected or inflamed tissue or when breaks in the aseptic technique occur), patient characteristics (such as age, comorbidities, medication use and smoking) and procedure factors (such as setting, surgical technique, type of procedure, duration and body region involved)...
August 2016: Revista Médica de Chile
https://www.readbyqxmd.com/read/27905632/-co-infection-by-chikungunya-virus-chik-v-and-dengue-virus-den-v-during-a-recent-outbreak-in-cali-colombia-report-of-a-fatal-case
#19
Fernando Rosso, Robinson Pacheco, Sarita Rodríguez, Diego Bautista
The recent outbreaks of Chikungunya (CHIK-V) virus in endemic areas of dengue (DEN-V) could increase the risk of co-infection. CHIK infection has been considered not severe and with very unusual mortality, however DEN is associated with severe manifestations and increased mortality. Little is known about coinfection. It is possible that co-infection could generate severe cases. We present a case report of co-infection DEN-V -3 and CHIK-V in an elderly patient who developed acute renal failure, dengue shock syndrome (DSS), progresses to multiple organ failure and died...
August 2016: Revista Chilena de Infectología: órgano Oficial de la Sociedad Chilena de Infectología
https://www.readbyqxmd.com/read/27905626/-study-of-toxocara-sp-eggs-in-soils-of-public-areas-of-the-city-of-chill%C3%A3-n-chile
#20
Millaray Melín-Coloma, Carmen Villaguala-Pacheco, Raúl Lisboa-Navarro, Carlos Landaeta-Aqueveque
INTRODUCTION: Squares and public areas are mentioned frequently as source of infections by Toxocara sp. for people. There is no study of the presence of Toxocara sp. eggs in soils of the city of Chillán, Chile. AIMS: To assess the presence of toxocara eggs in the soils of public areas of Chillán. MATERIAL AND METHODS: 43 public areas were studied in January of 2014. Samples were processed by sedimentation-flotation method. In addition, two positive control assays were performed: one with feces contaminated with Toxocara eggs mixed with soil; and the other leaving the feces on the soil and then analyzing this soil...
August 2016: Revista Chilena de Infectología: órgano Oficial de la Sociedad Chilena de Infectología
keyword
keyword
55908
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"