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https://www.readbyqxmd.com/read/27909682/case-report-of-invasive-disseminated-candidiasis-with-peripheral-nodular-cavitary-lesions-in-the-lung
#1
Hafiza Arshad, Silvia Garcia, Misbahuddin Khaja
We report a case of invasive candidiasis presenting as multiple lung nodules and cavitary lesions with minimal pleural effusion. Candida infections of the lung are rare but can occur after hematologic dissemination of the yeast from other body sites, such as the skin and the gastrointestinal and genitourinary tracts. Here, we describe the case of a 56-year-old female with a history of end-stage renal disease (ESRD) who presented with fever, productive cough, and pulmonary nodules and cavitary lesions seen on a chest computed tomography (CT)...
2017: Respiratory Medicine Case Reports
https://www.readbyqxmd.com/read/27660305/the-agreement-between-auscultation-and-lung-ultrasound-in-hemodialysis-patients-the-lust-study
#2
Claudia Torino, Luna Gargani, Rosa Sicari, Krzysztof Letachowicz, Robert Ekart, Danilo Fliser, Adrian Covic, Kostas Siamopoulos, Aristeidis Stavroulopoulos, Ziad A Massy, Enrico Fiaccadori, Alberto Caiazza, Thomas Bachelet, Itzchak Slotki, Alberto Martinez-Castelao, Marie-Jeanne Coudert-Krier, Patrick Rossignol, Faikah Gueler, Thierry Hannedouche, Vincenzo Panichi, Andrzej Wiecek, Giuseppe Pontoriero, Pantelis Sarafidis, Marian Klinger, Radovan Hojs, Sarah Seiler-Mussler, Fabio Lizzi, Dimitrie Siriopol, Olga Balafa, Linda Shavit, Rocco Tripepi, Francesca Mallamaci, Giovanni Tripepi, Eugenio Picano, Gérard Michel London, Carmine Zoccali
BACKGROUND AND OBJECTIVES: Accumulation of fluid in the lung is the most concerning sequela of volume expansion in patients with ESRD. Lung auscultation is recommended to detect and monitor pulmonary congestion, but its reliability in ESRD is unknown. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: In a subproject of the ongoing Lung Water by Ultra-Sound Guided Treatment to Prevent Death and Cardiovascular Complications in High Risk ESRD Patients with Cardiomyopathy Trial, we compared a lung ultrasound-guided ultrafiltration prescription policy versus standard care in high-risk patients on hemodialysis...
November 7, 2016: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/27660303/anxiety-in-patients-treated-with-hemodialysis
#3
Scott D Cohen, Daniel Cukor, Paul L Kimmel
Anxiety is a common yet frequently overlooked psychiatric symptom in patients with ESRD treated with hemodialysis (HD). Anxiety is characterized by disruptive feelings of uncertainty, dread, and fearfulness. A variety of common medical complaints may be manifestations of an anxiety disorder, including palpitations, tremors, indigestion, numbness/tingling, nervousness, shortness of breath, diaphoresis, and fear. It is essential for the clinician to rule out specific medical conditions, including cardiovascular, pulmonary, and neurologic diseases, before ascribing these symptoms to an anxiety disorder...
September 22, 2016: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/27574402/pharmacokinetic-profile-of-defibrotide-in-patients-with-renal-impairment
#4
Paola Tocchetti, Elena Tudone, Jean-Francois Marier, Thomas C Marbury, Katie Zomorodi, Mark Eller
Hepatic veno-occlusive disease, also called sinusoidal obstruction syndrome (VOD/SOS), is an unpredictable, potentially life-threatening complication of hematopoietic stem cell transplant conditioning. Severe VOD/SOS, generally associated with multiorgan dysfunction (pulmonary or renal dysfunction), may be associated with >80% mortality. Defibrotide, recently approved in the US, has demonstrated efficacy treating hepatic VOD/SOS with multiorgan dysfunction. Because renal impairment is prevalent in patients with VOD/SOS, this Phase I, open-label, two-part study in adults examined the effects of hemodialysis and severe or end-stage renal disease (ESRD) on defibrotide pharmacokinetics (PK)...
2016: Drug Design, Development and Therapy
https://www.readbyqxmd.com/read/27499694/predictive-value-of-echocardiographic-abnormalities-and-the-impact-of-diastolic-dysfunction-on-in-hospital-major-cardiovascular-complications-after-living-donor-kidney-transplantation
#5
Eun Jung Kim, Suyon Chang, So Yeon Kim, Kyu Ha Huh, Soojeong Kang, Yong Seon Choi
Patients with end-stage renal disease (ESRD) show characteristic abnormalities in cardiac structure and function. We evaluated the influence of these abnormalities on adverse cardiopulmonary outcomes after living donor kidney transplantation in patients with valid preoperative transthoracic echocardiographic evaluation. We then observed any development of major postoperative cardiovascular complications and pulmonary edema until hospital discharge. In-hospital major cardiovascular complications were defined as acute myocardial infarction, ventricular fibrillation/tachycardia, cardiogenic shock, newly-onset atrial fibrillation, clinical pulmonary edema requiring endotracheal intubation or dialysis...
2016: International Journal of Medical Sciences
https://www.readbyqxmd.com/read/27460913/sitagliptin-and-risk-of-heart-failure-hospitalization-in-patients-with-type-2-diabetes-on-dialysis-a-population-based-cohort-study
#6
Yi-Chih Hung, Che-Chen Lin, Wei-Lun Huang, Man-Ping Chang, Ching-Chu Chen
The incidence of heart failure hospitalization (HHF) after taking sitagliptin in type 2 diabetes (T2DM) patients with end stage renal disease (ESRD) on dialysis is unclear. In this population-based cohort study, we identified individuals with T2DM and ESRD on dialysis who were treated with sitagliptin between 2009 and 2011 and randomly selected a control cohort matched by age, sex, duration of T2DM, hypertension medications, use of statin and aspirin, sulfonylureas, glinides, and insulin usage, atherosclerotic heart disease, congestive heart failure and chronic obstructive pulmonary disease at a 1:4 ratio...
2016: Scientific Reports
https://www.readbyqxmd.com/read/27423711/arteriovenous-fistula-creation-for-end-stage-renal-disease-may-worsen-the-pulmonary-hypertension
#7
Jurabek Babadjanov, Roy Miler, Kurt Niebauer, Lee Kirksey
Pulmonary hypertension (PH) is an increase in pulmonary arterial pressure secondary to narrowing and obliteration of the lumen of the lung vessels resulting in an increased resistance to flow. It is defined by a mean pulmonary arterial pressure (mPAP) ≥25 mmHg at rest usually confirmed by right heart catheterization compared with normal mPAP of ≤20 mmHg. The primary etiology of PH is unclear, although it can be from heart, lung or systemic disease. Patients with End-Stage Renal Disease (ESRD) are at increased risk of developing PH, with up to 39% of patients with an arteriovenous fistula developing PH [7-9,15]...
July 13, 2016: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/27367547/quality-of-end-of-life-care-provided-to-patients-with-different-serious-illnesses
#8
Melissa W Wachterman, Corey Pilver, Dawn Smith, Mary Ersek, Stuart R Lipsitz, Nancy L Keating
IMPORTANCE: Efforts to improve end-of-life care have focused primarily on patients with cancer. High-quality end-of-life care is also critical for patients with other illnesses. OBJECTIVE: To compare patterns of end-of-life care and family-rated quality of care for patients dying with different serious illnesses. DESIGN, SETTING, AND PARTICIPANTS: A retrospective cross-sectional study was conducted in all 146 inpatient facilities within the Veteran Affairs health system among patients who died in inpatient facilities between October 1, 2009, and September 30, 2012, with clinical diagnoses categorized as end-stage renal disease (ESRD), cancer, cardiopulmonary failure (congestive heart failure or chronic obstructive pulmonary disease), dementia, frailty, or other conditions...
August 1, 2016: JAMA Internal Medicine
https://www.readbyqxmd.com/read/27362965/assessment-of-respiratory-complications-associated-with-end-stage-renal-disease-in-northern-saudi-arabia
#9
Mohammed Abdulrahman S Alosayfir, Fahad Khaled Fahad Almuzaini, Mohammed Fahad Mohammed Alateeq, Kheder Mohamed Altayep, Hussain Gadelkarim Ahmed
BACKGROUND: The prevalence of End Stage Renal Disease (ESRD) is increasing in different parts of Kingdom of Saudi Arabia (KSA), particularly Hail Region, therefore, the aim of this study was to assess the respiratory complications that associated with ESRD. METHODS: In the present study, clinical, imaging and laboratory parameters were identified for 100 ESRD patients with ESRD who were referred to the Pulmonary Medicine Department at King Khalid Hospital. RESULTS: Pulmonary Edema, Pneumonia, and Pleural effusion, were identified in 22%, 14%, and 16% of the referred ESRD patients, respectively...
June 29, 2016: Romanian Journal of Internal Medicine, Revue Roumaine de Médecine Interne
https://www.readbyqxmd.com/read/27336884/increased-risk-of-atrial-fibrillation-in-end-stage-renal-disease-patients-on-dialysis-a-nationwide-population-based-study-in-taiwan
#10
Cheng-Huang Shen, Cai-Mei Zheng, Kee-Thai Kiu, Hsin-An Chen, Chia-Chang Wu, Kuo-Cheng Lu, Yung-Ho Hsu, Yuh-Feng Lin, Yuan-Hung Wang
End-stage renal disease (ESRD) patients commonly have a higher risk of developing cardiovascular diseases than general population. Chronic kidney disease is an independent risk factor for atrial fibrillation (AF); however, little is known about the AF risk among ESRD patients with various modalities of renal replacement therapy. We used the Taiwan National Health Insurance Research Database to determine the incident AF among peritoneal dialysis (PD) and hemodialysis (HD) patients in Taiwan.Our ESRD cohort include Taiwan National Health Insurance Research Database, we identified 15,947 patients, who started renal replacement therapy between January 1, 2002 and December 31, 2003...
June 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27300444/hydrogen-peroxide-prevents-vascular-calcification-induced-ros-production-by-regulating-nrf-2-pathway
#11
Wensong Zhang, Yi Li, Hanlu Ding, Yaqin Du, Li Wang
BACKGROUND: Although vascular calcification in end-stage renal disease (ESRD) represents a ubiquitous human health problem, effective therapies with limited side effects are still lacking, and the precise mechanisms are not fully understood. The Nrf-2/ARE pathway is a pivotal to regulate anti-oxidative responses in vascular calcification upon ESRD. Although Nrf-2 plays a crucial role in atherosclerosis, pulmonary fibrosis, and brain ischemia, the effect of Nrf-2 and oxidative stress on vascular calcification in ESRD patients is still unclear...
August 2016: Renal Failure
https://www.readbyqxmd.com/read/27195764/remote-monitoring-of-chronic-diseases-a-landscape-assessment-of-policies-in-four-european-countries
#12
Katherine Rojahn, Suzanne Laplante, James Sloand, Claire Main, Aftab Ibrahim, Janet Wild, Nicky Sturt, Thelga Areteou, K Ian Johnson
BACKGROUND: Remote monitoring (RM) is defined as the surveillance of device-transmitted outpatient data. RM is expected to enable better management of chronic diseases. The objective of this research was to identify public policies concerning RM in four European countries. METHODS: Searches of the medical literature, the Internet, and Ministry of Health websites for the United Kingdom (UK), Germany, Italy, and Spain were performed in order to identify RM policies for chronic diseases, including end stage renal disease (ESRD), chronic pulmonary obstructive disease (COPD), diabetes, heart failure, and hypertension...
2016: PloS One
https://www.readbyqxmd.com/read/27006497/improving-outcomes-in-patients-receiving-dialysis-the-peer-kidney-care-initiative
#13
James B Wetmore, David T Gilbertson, Jiannong Liu, Allan J Collins
The past decade has witnessed a marked reduction in mortality rates among patients receiving maintenance dialysis. However, the reasons for this welcome development are uncertain, and greater understanding is needed to translate advances in care into additional survival gains. To fill important knowledge gaps and to enable dialysis provider organizations to learn from one another, with the aim of advancing patient care, the Peer Kidney Care Initiative (Peer) was created in 2014 by the chief medical officers of 14 United States dialysis provider organizations and the Chronic Disease Research Group...
July 7, 2016: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/26948291/double-filtration-plasmapheresis-in-the-treatment-of-antineutrophil-cytoplasmic-autoantibody-associated-vasculitis-with-severe-renal-failure-a-preliminary-study-of-15-patients
#14
Yinghua Chen, Liu Yang, Kang Li, Zhengzhao Liu, Dehua Gong, Haitao Zhang, Zhihong Liu, Weixin Hu
Our aim was to investigate the clinical efficacy of double filtration plasmapheresis (DFPP) in the treatment of antineutrophil cytoplasmic autoantibody-(ANCA) associated vasculitis (AAV) with severe renal involvement. Fifteen AAV patients who had severe renal failure (median SCr 5.6(IQR 5.2-9.0) mg/dL) and needed initial renal replacement therapy (RRT) were treated with DFPP and immunosuppressive therapy. Two plasma volumes were processed during each DFPP session. The changes of serum ANCA and renal function were investigated...
April 2016: Therapeutic Apheresis and Dialysis
https://www.readbyqxmd.com/read/26888091/prevalence-and-risk-factors-for-pulmonary-arterial-hypertension-in-end-stage-renal-disease-patients-undergoing-continuous-ambulatory-peritoneal-dialysis
#15
Lei Zhang, Shiqi Zhao, Jinling Ma, Jian Gong, Guizhen Qiu, Yueqin Ren, Ying Zen, Yongbing Shi
BACKGROUND: Pulmonary arterial hypertension (PAH) is a major complication in renal failure patients, but very little information is available on the cardiovascular parameters in these patients. The prevalence and risk factors for PAH were systematically evaluated in patients with end-stage renal diseases (ESRD) undergoing continuous ambulatory peritoneal dialysis (CAPD). METHODS: Between January 2010 and January 2014, 177 ESRD patients (85 males and 92 females) undergoing CAPD therapy were recruited...
June 2016: Renal Failure
https://www.readbyqxmd.com/read/26808530/dignity-and-distress-towards-the-end-of-life-across-four-non-cancer-populations
#16
MULTICENTER STUDY
Harvey Max Chochinov, Wendy Johnston, Susan E McClement, Thomas F Hack, Brenden Dufault, Murray Enns, Genevieve Thompson, Mike Harlos, Ronald W Damant, Clare D Ramsey, Sara Davison, James Zacharias, Doris Milke, David Strang, Heather J Campbell-Enns, Maia S Kredentser
OBJECTIVE: The purpose of this study was to identify four non-cancer populations that might benefit from a palliative approach; and describe and compare the prevalence and patterns of dignity related distress across these diverse clinical populations. DESIGN: A prospective, multi-site approach was used. SETTING: Outpatient clinics, inpatient facilities or personal care homes, located in Winnipeg, Manitoba and Edmonton, Alberta, Canada. PARTICIPANTS: Patients with advanced Amyotrophic Lateral Sclerosis (ALS), Chronic Obstructive Pulmonary Disease (COPD), End Stage Renal Disease (ESRD); and the institutionalized alert frail elderly...
2016: PloS One
https://www.readbyqxmd.com/read/26601085/comparing-right-ventricular-function-and-pulmonary-artery-pressure-before-and-shortly-after-hemodialysis-in-patients-with-end-stage-renal-disease
#17
Jamshid Najafian, Shahram Taheri, Behzad Mahaki, Safieh Molavi, Samaneh Alami, Somayeh Khalesi, Asma Salehi
BACKGROUND: Early screening and diagnosis of right ventricular (RV) dysfunction and pulmonary artery hypertension is vital in patients with end-stage renal disease (ESRD) because of its relation to patients' survival. The present study is aimed to address and compare RV function parameters and pulmonary artery pressure (PAP) before and shortly after hemodialysis in patients with ESRD. MATERIALS AND METHODS: This quasi-experimental study performed at Alzahra Hospital in Isfahan in 2014, 40 consecutive patients with ESRD that referred to hemodialysis ward were assessed by M-mode echocardiography and tissue Doppler imaging before and 30 min after completing hemodialysis to assess RV function parameters and PAP...
2015: Advanced Biomedical Research
https://www.readbyqxmd.com/read/26527323/echocardiographic-assessment-of-right-ventricular-functions-in-nondiabetic-normotensive-hemodialysis-patients
#18
Yusuf Karavelioğlu, Sultan Özkurt, Macit Kalçik, Hekim Karapinar, Arif Arisoy
PURPOSE: Heart is affected structurally and functionally in end-stage renal disease (ESRD). However, the data available about adverse effects of ESRD on right ventricle (RV) is scarce. We aimed to evaluate echocardiographic parameters of RV in nondiabetic, normotensive patients with ESRD undergoing hemodialysis (HD). METHODS: A total of 45 (24 women; mean age 52.4 ± 12.4 years) consecutive nondiabetic, normotensive patients with ESRD undergoing HD and 39 healthy age and sex-matched control subjects (22 women; mean age 50...
September 2015: Interventional Medicine & Applied Science
https://www.readbyqxmd.com/read/26484016/relationship-between-pulmonary-hypertension-peripheral-vascular-calcification-and-major-cardiovascular-events-in-dialysis-patients
#19
Sun Chul Kim, Hyo Jung Chang, Myung-Gyu Kim, Sang-Kyung Jo, Won-Yong Cho, Hyoung-Kyu Kim
BACKGROUND: Pulmonary hypertension (PHT) is a recently recognized complication of chronic kidney disease. In this study, we investigated the association between PHT, peripheral vascular calcifications (VCs), and major cardiovascular events. METHODS: In this retrospective study, we included 172 end-stage renal disease (ESRD) patients undergoing dialysis [hemodialysis (HD)=84, peritoneal dialysis=88]. PHT was defined as an estimated pulmonary artery systolic pressure>37 mmHg using echocardiography...
March 2015: Kidney Research and Clinical Practice
https://www.readbyqxmd.com/read/26379713/clinicoradiological-profile-of-lower-lung-field-tuberculosis-cases-among-young-adult-and-elderly-people-in-a-teaching-hospital-of-madhya-pradesh-india
#20
Saurabh Kumar Singh, Kamlesh Kumar Tiwari
Aim. To study the clinical and radiological features of lower lung field tuberculosis (LLFTB) in relation to the patients of nonlower lung field tuberculosis (non-LLFTB). Material and Methods. All the patients of lower lung field tuberculosis defined by the lesions below an arbitrary line across the hila in their chest X-rays were included in the study. Their sputum for acid fast bacilli, HIV, blood sugar, and other relevant investigations were performed. Results. The total of 2136 cases of pulmonary tuberculosis was studied...
2015: Journal of Tropical Medicine
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