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https://www.readbyqxmd.com/read/29908891/transesophageal-echocardiography-guidance-for-robot-assisted-level-iii-inferior-vena-cava-tumor-thrombectomy-a-novel-approach-to-intraoperative-care
#1
Michael Essandoh, Jonathan Tang, Grace Essandoh, Manoj H Iyer, Joseph Kuhn, Keith Opat, Victor L Mandoff, Geoffrey N Box
No abstract text is available yet for this article.
June 13, 2018: Journal of Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/29893658/a-retrospective-analysis-of-adverse-events-among-patients-receiving-daptomycin-versus-vancomycin-during-outpatient-parenteral-antimicrobial-therapy
#2
Gregory M Schrank, Sharon B Wright, Westyn Branch-Elliman, Mary T LaSalvia
OBJECTIVE: Outpatient parenteral antimicrobial therapy (OPAT) is a safe and effective alternative to prolonged inpatient stays for patients requiring long-term intravenous antimicrobials, but antimicrobial-associated adverse events remain a significant challenge. Thus, we sought to measure the association between choice of antimicrobial agent (vancomycin vs daptomycin) and incidence of adverse drug events (ADEs). METHODS: Patients receiving OPAT treatment with vancomycin or daptomycin for skin and soft-tissue infections, bone and joint infections, endocarditis, and bacteremia or endovascular infections during the period from July 1, 2013, through September 30, 2016, were included...
June 12, 2018: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/29878218/quality-indicators-assessing-antibiotic-use-in-the-outpatient-setting-a-systematic-review-followed-by-an-international-multidisciplinary-consensus-procedure
#3
Marion Le Maréchal, Gianpiero Tebano, Annelie A Monnier, Niels Adriaenssens, Inge C Gyssens, Benedikt Huttner, Romina Milanic, Jeroen Schouten, Mirjana Stanic Benic, Ann Versporten, Vera Vlahovic-Palcevski, Veronica Zanichelli, Marlies E Hulscher, Céline Pulcini
Objectives: Quality indicators (QIs) assessing the appropriateness of antibiotic use are essential to identify targets for improvement and guide antibiotic stewardship interventions. The aim of this study was to develop a set of QIs for the outpatient setting from a global perspective. Methods: A systematic literature review was performed by searching MEDLINE and relevant web sites in order to retrieve a list of QIs. These indicators were extracted from published trials, guidelines, literature reviews or consensus procedures...
June 1, 2018: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/29784453/executive-summary-of-outpatient-parenteral-antimicrobial-therapy-guidelines-of-the-spanish-society-of-clinical-microbiology-and-infectious-diseases-and-the-spanish-domiciliary-hospitalisation-society
#4
Luis Eduardo López Cortés, Abel Mujal Martínez, Magdalena Fernández Martínez de Mandojana, Natalia Martín, Mercè Gil Bermejo, Joan Solà Aznar, Eulalia Villegas Bruguera, Maria José Peláez Cantero, Pilar Retamar Gentil, Miriam Delgado Vicente, Víctor José González-Ramallo, Miguel Ángel Ponce González, Manuel Mirón Rubio, M Montserrat Gómez Rodríguez de Mendarozqueta, Miguel Ángel Goenaga Sánchez, Pedro Sanroma Mendizábal, Elena Delgado Mejía, Marcos Pajarón Guerrero
Outpatient parenteral antimicrobial therapy (OPAT) programmes make it possible to start or complete intravenous antimicrobial therapy for practically any type of infection at home, provided that patient selection is appropriate for the type of OPAT programme available. Although the clinical management of infections in the home setting is comparable in many respects to that offered in conventional hospitalization (selection of antibiotics, duration of treatment, etc.), there are many aspects that are specific to this care modality...
May 18, 2018: Enfermedades Infecciosas y Microbiología Clínica
https://www.readbyqxmd.com/read/29766017/outcomes-according-to-discharge-location-for-persons-who-inject-drugs-receiving-outpatient-parenteral-antimicrobial-therapy
#5
Helen T D'Couto, Gregory K Robbins, Kevin L Ard, Sarah E Wakeman, Justin Alves, Sandra B Nelson
Background: Opioid use disorder poses a significant public health risk. Persons who inject drugs (PWID) suffer from high mortality and morbidity secondary to serious infectious diseases, often requiring prolonged courses of outpatient parenteral antibiotics. The goal of this study was to determine the outcomes of PWID discharged to home or to a skilled nursing or rehabilitation facility (SNF/rehab) with parenteral antibiotic treatment under an outpatient parenteral antimicrobial therapy (OPAT) program...
May 2018: Open Forum Infectious Diseases
https://www.readbyqxmd.com/read/29705391/stability-of-benzylpenicillin-potassium-and-ampicillin-in-an-elastomeric-infusion-pump
#6
Tomomi Nakamura, Yuki Enoki, Shunsuke Uno, Yoshifumi Uwamino, Osamu Iketani, Naoki Hasegawa, Kazuaki Matsumoto
Some infectious diseases, such as infective endocarditis, osteomyelitis, and abscesses, require treatment with long-term intravenous antimicrobial treatment. Therefore, the patient is required to stay in the hospital to receive therapy, which lowers their quality of life. Establishing an outpatient parenteral antimicrobial therapy (OPAT) by continuous infusion pump is desired in Japan to overcome these issues. However, the 24-h stability of antimicrobial agents dissolved in infusion solutions is unclear. Thus, we investigated the stability of antimicrobial agents in five different infusion solutions in a clinical setting...
April 25, 2018: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://www.readbyqxmd.com/read/29685397/outcomes-of-outpatient-parenteral-antimicrobial-therapy-in-patients-with-injection-drug-use
#7
Mohsen Vazirian, Jason M Jerry, Nabin K Shrestha, Steven M Gordon
BACKGROUND: Historically, there has been a restrictive approach toward outpatient parenteral antimicrobial therapy (OPAT) in patients with injection drug use (IDU) due to the fear that they might utilize the intravenous catheter to inject illicit substances. OBJECTIVE: We tested the hypothesis that patients with current IDU on OPAT would have less favorable treatment outcomes compared to those without current IDU. METHODS: In this retrospective cohort chart review study of Cleveland Clinic OPAT registry, we identified patients with current IDU by both electronic and manual review...
March 3, 2018: Psychosomatics
https://www.readbyqxmd.com/read/29684172/emergency-department-visits-during-outpatient-parenteral-antimicrobial-therapy-a-retrospective-cohort-study
#8
Nabin K Shrestha, So Lim Kim, Susan J Rehm, Angela Everett, Steven M Gordon
Objectives: Patients receiving outpatient parenteral antimicrobial therapy (OPAT) may require emergency department (ED) visits to manage complications. This study's purpose was to identify risk factors for ED visits during OPAT and risk factors for hospitalization among patients with ED visits. Methods: All OPAT courses initiated between 1 January 2013 and 1 January 2017 at Cleveland Clinic were identified. The first OPAT course per patient was included. For these, ED visits within 30 days were identified...
April 18, 2018: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/29613971/the-impact-of-pediatric-outpatient-parenteral-antibiotic-therapy-implementation-at-a-tertiary-children-s-hospital-in-the-united-kingdom
#9
Sanjay Patel, Valentina Burzio, Helen Green, Sara Rees, Marc Tebruegge, Christine Jones, Saul N Faust
BACKGROUND: Recent advances in outpatient parenteral antibiotic therapy (OPAT) have largely focused on adult practice, and there are few published data on the safety and effectiveness of pediatric OPAT (p-OPAT). METHODS: During a 3-year-period (2012 to 2015), data were prospectively collected on patients managed within the p-OPAT service at Southampton Children's Hospital, a tertiary pediatric hospital in the South of England. RESULTS: A total of 130 p-OPAT episodes were managed during this period...
April 2, 2018: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/29534769/incidence-and-risk-factors-for-healthcare-utilisation-among-patients-discharged-on-outpatient-parenteral-antimicrobial-therapy
#10
D M Jacobs, W-Y Leung, D Essi, W Park, A Shaver, J Claus, C Ruh, G G Rao
Outpatient parenteral antimicrobial therapy (OPAT) programmes facilitate hospital discharge, but patients remain at risk of complications and consequent healthcare utilisation (HCU). Here we elucidated the incidence of and risk factors associated with HCU in OPAT patients. This was a retrospective, single-centre, case-control study of adult patients discharged on OPAT. Cases (n = 63) and controls (n = 126) were patients that did or did not utilise the healthcare system within 60 days. Characteristics associated with HCU in bivariate analysis (P ≤ 0...
April 2018: Epidemiology and Infection
https://www.readbyqxmd.com/read/29503118/delayed-onset-aorto-right-ventricular-fistula-complicating-sutureless-aortic-valve-replacement
#11
Joseph Kuhn, Keith Opat, Michael Essandoh, Antolin Flores
No abstract text is available yet for this article.
January 31, 2018: Journal of Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/29494367/an-assessment-of-an-outpatient-antimicrobial-therapy-program-in-a-rural-medical-center-a-retrospective-chart-review
#12
Matthew Shawn Burkett, Angela Macci Bires, Thomas W Cline, Anthony Knight
Current literature supports outpatient parenteral antimicrobial therapy (OPAT). This article presents results from a research study that evaluated an OPAT program that treated community-acquired pneumonia. If patients had the opportunity to receive outpatient intravenous antibiotics for community-acquired pneumonia, would this prevent future hospitalization? Was there a decrease in hospital admissions? An informal cost-benefit analysis comparing OPAT with inpatient hospital admissions for the same disease was also reviewed to provide evidence whether there was a change...
April 2018: Critical Care Nursing Quarterly
https://www.readbyqxmd.com/read/29493791/antimicrobial-agents-and-catheter-complications-in-outpatient-parenteral-antimicrobial-therapy
#13
Sara C Keller, Kathryn Dzintars, Lisa A Gorski, Deborah Williams, Sara E Cosgrove
OBJECTIVES: Debate about whether certain antimicrobial agents traditionally considered vesicants increase the risk of catheter complications has led to uncertainty in venous catheter placement protocols. To understand whether patients requiring home-based outpatient parenteral antimicrobial therapy (OPAT) should receive peripheral catheters (e.g., midline catheters) versus central venous catheters, and to understand whether certain antimicrobial agents place home-based OPAT patients at higher risk for catheter complications, we investigated associations between antimicrobial agent(s) and catheter complications...
April 2018: Pharmacotherapy
https://www.readbyqxmd.com/read/29481658/bias-corrected-estimates-of-time-varying-adverse-drug-event-rates-for-patients-on-outpatient-parenteral-antimicrobial-therapy-opat
#14
Alan C Kinlaw, Ashley H Marx, Claire E Farel
No abstract text is available yet for this article.
February 22, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29477102/treatment-strategies-outcomes-and-prognostic-factors-in-291-patients-with-secondary-cns-involvement-by-diffuse-large-b-cell-lymphoma
#15
Tarec Christoffer El-Galaly, Chan Yoon Cheah, Mette Dahl Bendtsen, Grzegorz S Nowakowski, Roopesh Kansara, Kerry J Savage, Joseph M Connors, Laurie H Sehn, Neta Goldschmidt, Adir Shaulov, Umar Farooq, Brian K Link, Andrés J M Ferreri, Teresa Calimeri, Caterina Cecchetti, Eldad J Dann, Carrie A Thompson, Tsofia Inbar, Matthew J Maurer, Inger Lise Gade, Maja Bech Juul, Jakob W Hansen, Staffan Holmberg, Thomas S Larsen, Sabrina Cordua, N George Mikhaeel, Martin Hutchings, John F Seymour, Michael Roost Clausen, Daniel Smith, Stephen Opat, Michael Gilbertson, Gita Thanarajasingam, Diego Villa
PURPOSE: Secondary CNS involvement (SCNS) is a profoundly adverse complication of diffuse large B-cell lymphoma. Evidence from older series indicated a median overall survival (OS) < 6 months; however, data from the immunochemotherapy era are limited. METHODS: Patients diagnosed with SCNS during or after first-line immunochemotherapy were identified from databases and/or regional/national registries from three continents. Clinical information was retrospectively collected from medical records...
April 2018: European Journal of Cancer
https://www.readbyqxmd.com/read/29464675/outpatient-parenteral-antibiotic-therapy-in-a-suburban-tertiary-referral-centre-in-australia-over-10-years
#16
Wenlong Li, James Branley, Archana Sud
PURPOSE: Outpatient parenteral antibiotic therapy (OPAT) is a widely accepted and safe therapeutic option for carefully selected patients. This study reviewed the practice of an OPAT service in a large Australian tertiary teaching hospital in Western Sydney over a 10-year period. METHOD: Data were retrieved from a prospectively maintained electronic database which included information on patient demographics, clinical diagnosis, microbiological identity, antimicrobial therapy, complications and readmissions...
February 20, 2018: Infection
https://www.readbyqxmd.com/read/29412536/introducing-outpatient-parenteral-antimicrobial-therapy-in-a-children-s-hospital
#17
Sally Bolsover
Outpatient parenteral antimicrobial therapy (OPAT) offers an alternative to inpatient care for delivering intravenous antibiotics in patients' homes or in a day care clinic setting. It was first introduced in North America in the 1970s and has evolved over the years, starting with the adult population and now moving to the paediatric population ( Chapman 2013 ). OPAT has the potential to offer excellent, patient-centred, high-quality care to treat a wide variety of infectious conditions in patients who are medically stable and do not need hospitalisation...
February 7, 2018: Nursing Children and Young People
https://www.readbyqxmd.com/read/29385901/opat-proof-of-concept-in-a-peripheral-belgian-hospital-after-review-of-the-literature
#18
Annick Smismans, Astrid Vantrappen, Freija Verbiest, Christophe Indevuyst, Bea Van den Poel, Sandrina von Winckelmann, Annelore Peeters, Sara Ombelet, Peter Lybeert, Andre Heremans, Eric Frans, Erwin Ho, Johan Frans
Since its introduction in the 1970s in the United States, outpatient parenteral antibiotic/antimicrobial therapy (OPAT) has been adopted internationally for long-term intravenous (IV) treatment of stable infectious diseases. The aim is to provide a safe and successful completion of IV antimicrobial treatment at the ambulatory care center or at home without complications and costs associated with hospitalization. OPAT implementation has been accelerated by progress in vascular access devices, newly available antibiotics, the emphasis on cost-savings, as well as an improved patient comfort and a reduced incidence of health care associated infections with a similar outcome...
January 31, 2018: Acta Clinica Belgica
https://www.readbyqxmd.com/read/29326190/a-qualitative-study-of-patients-feedback-about-outpatient-parenteral-antimicrobial-therapy-opat-services-in-northern-england-implications-for-service-improvement
#19
Maureen Twiddy, Carolyn J Czoski Murray, Samantha J Mason, David Meads, Judy M Wright, Elizabeth D Mitchell, Jane Minton
OBJECTIVE: Outpatient parenteral antimicrobial therapy (OPAT) provides opportunities for improved cost savings, but in the UK, implementation is patchy and a variety of service models are in use. The slow uptake in the UK and Europe is due to a number of clinical, financial and logistical issues, including concern about patient safety. The measurement of patient experience data is commonly used to inform commissioning decisions, but these focus on functional aspects of services and fail to examine the relational aspects of care...
January 10, 2018: BMJ Open
https://www.readbyqxmd.com/read/29318305/geographical-origin-characterization-of-slovenian-organic-garlic-using-stable-isotope-and-elemental-composition-analyses
#20
Anja Mahne Opatić, Marijan Nečemer, David Kocman, Sonja Lojen
In the present research, the applicability of stable isotope (δ13C, δ15N, δ34S, δ18O) and multi-element (P, S, Cl, K, Ca, Zn, Br, Rb, Sr) data for determining the geographical origin of garlic (Allium sativum L.) at the scale of Slovenia was examined. Slovenia is a rather small country (20273 km2) with significant geological and biological diversity. Garlic, valued for its medicinal properties, was collected from Slovenian farms with certified organic production and analyzed by elemental analyzer isotope ratio mass spectrometry combined with energy dispersive X- ray fluorescence spectrometry...
December 2017: Acta Chimica Slovenica
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