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Menarche and diabetes

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https://www.readbyqxmd.com/read/27899085/oestradiol-levels-and-superoxide-dismutase-activity-in-age-related-cataract-a-case-control-study
#1
Dragana Škiljić, Staffan Nilsson, Anne Petersen, Jan-Olof Karlsson, Anders Behndig, Lada Kalaboukhova, Madeleine Zetterberg
BACKGROUND: It has been suggested that the higher prevalence of cataract in women is caused by a withdrawal effect of oestrogen at menopause. In vitro studies have demonstrated protection of serum oestradiol (E2) against oxidative stress through upregulation of antioxidant enzymes, including superoxide dismutase (SOD). The purpose of the present study was to investigate E2 levels and SOD erythrocyte activity in patients with age-related cataract. METHODS: The studied subjects consisted of 103 patients with age-related cataract and 22 controls...
November 29, 2016: BMC Ophthalmology
https://www.readbyqxmd.com/read/27798047/common-diseases-as-determinants-of-menopausal-age
#2
Jingmei Li, Mikael Eriksson, Kamila Czene, Per Hall, Kenny A Rodriguez-Wallberg
STUDY QUESTION: Can the diagnosis of common diseases before menopause influence age at natural menopause (ANM) onset? SUMMARY ANSWER: Polycystic ovary syndrome (PCOS) and depression were observed to delay menopause. WHAT IS KNOWN ALREADY: It has been observed that women who undergo early menopause experience a higher burden of health problems related to metabolic syndromes, heart disease and depression, but whether ANM can be influenced by common adult diseases has not been studied extensively...
October 18, 2016: Human Reproduction
https://www.readbyqxmd.com/read/27765126/-association-and-interaction-between-age-at-menarche-and-risk-of-diabetes-in-adult-women
#3
H Wang, R Y Hu, J M Zhong, Y J Qian, C M Wang, K X Xie, L L Chen, Z Bian, Y Guo, M Yu, Z M Chen, L M Li
Objective: To explore the associations between age at menarche and diabetes in adult women. Methods: We analyzed the baseline data of 32 364 female participants who were aged 30-79 years and had been enrolled into China Kadoorie Biobank (CKB) study from Tongxiang, Zhejiang province. Multiple logistic regression analysis were used to investigate the putative associations after adjusting for potential confounders. Variables of menarche age and others were added to the logistic regression model to evaluate the multiplicative interaction, respectively...
October 10, 2016: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/27721839/effects-of-early-menarche-on-physical-and-psychosocial-health-problems-in-adolescent-girls-and-adult-women
#4
Jae-Ho Yoo
The menarcheal age of Korean women has been rapidly decreasing for the last 50 years, and the average menarcheal age of women born in the 1990s is approaching 12.6 years. In addition, interest in early puberty has been increasing recently owing to the rapid increase in precocious puberty. Generally, out of concern for short stature and early menarche, idiopathic central precocious puberty in female adolescents is treated with gonadotropin-releasing hormone analogs. Studies to date have described the association between early menarche and psychosocial problems such as delinquency and risky sexual behavior, as well as physical health problems such as obesity, diabetes, cardiovascular diseases, and breast cancer throughout the lifespan of women...
September 2016: Korean Journal of Pediatrics
https://www.readbyqxmd.com/read/27699734/-overview-of-endometrial-cancer
#5
Chia-Chun Li, Tsui-Hsia Feng
Endometrial cancer is the most common gynecological cancer and the sixth most common cancer among women in Taiwan. Risk factors for endometrial cancer include obesity, long-term estrogen replacement therapy, diabetes mellitus, hypertension, nulliparty, early age at menarche, late age at menopause, and tamoxifen therapy. Most women with endometrial cancer exhibit abnormal uterine bleeding. Endometrial cancer is often diagnosed at stage I. Surgery alone is the primary treatment for stage I endometrial cancer...
October 2016: Hu Li za Zhi the Journal of Nursing
https://www.readbyqxmd.com/read/27621257/the-interlace-study-design-data-harmonization-and-characteristics-across-20-studies-on-women-s-health
#6
Gita D Mishra, Hsin-Fang Chung, Nirmala Pandeya, Annette J Dobson, Lee Jones, Nancy E Avis, Sybil L Crawford, Ellen B Gold, Daniel Brown, Lynette L Sievert, Eric Brunner, Janet E Cade, Victoria J Burley, Darren C Greenwood, Graham G Giles, Fiona Bruinsma, Alissa Goodman, Kunihiko Hayashi, Jung Su Lee, Hideki Mizunuma, Diana Kuh, Rachel Cooper, Rebecca Hardy, Carla Makhlouf Obermeyer, Kathryn A Lee, Mette Kildevæld Simonsen, Toyoko Yoshizawa, Nancy F Woods, Ellen S Mitchell, Mark Hamer, Panayotes Demakakos, Sven Sandin, Hans-Olov Adami, Elisabete Weiderpass, Debra Anderson
OBJECTIVES: The International Collaboration for a Life Course Approach to Reproductive Health and Chronic Disease Events (InterLACE) project is a global research collaboration that aims to advance understanding of women's reproductive health in relation to chronic disease risk by pooling individual participant data from several cohort and cross-sectional studies. The aim of this paper is to describe the characteristics of contributing studies and to present the distribution of demographic and reproductive factors and chronic disease outcomes in InterLACE...
October 2016: Maturitas
https://www.readbyqxmd.com/read/27546362/serum-soluble-lectin-like-oxidized-low-density-lipoprotein-receptor-1-levels-in-patients-with-restless-legs-syndrome
#7
G Halac, E Kilic, M A Cikrikcioglu, K Celik, A Toprak-Erek, S Keskin, I Gultepe, R S Celik, N Ozaras, A Yildiz, S Aydin, O Akan, C Karatoprak, Y Sekin, T Asil
OBJECTIVE: The aim of this study was to assess the predisposition for atherosclerosis in patients with RLS through serum sLOX-1 (serum Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1) measurements. BACKGROUND: Recent epidemiological studies have suggested an association of RLS with certain chronic conditions such as diabetes mellitus (DM), obesity, hypertension (HT), and hyperlipidemia. LOX-1 is expressed in endothelial cells, macrophages, and in smooth muscle cells under the effect of proatherogenic conditions...
2016: Bratislavské Lekárske Listy
https://www.readbyqxmd.com/read/27465714/reproductive-history-and-risk-of-type-2-diabetes-mellitus-in-postmenopausal-women-findings-from-the-women-s-health-initiative
#8
Erin S LeBlanc, Kristopher Kapphahn, Haley Hedlin, Manisha Desai, Nisha I Parikh, Simin Liu, Donna R Parker, Matthew Anderson, Vanita Aroda, Shannon Sullivan, Nancy F Woods, Molly E Waring, Cora E Lewis, Marcia Stefanick
OBJECTIVE: The aim of the study was to understand the association between women's reproductive history and their risk of developing type 2 diabetes. We hypothesized that characteristics signifying lower cumulative endogenous estrogen exposure would be associated with increased risk. METHODS: Prospective cohort analysis of 124,379 postmenopausal women aged 50 to 79 years from the Women's Health Initiative (WHI). We determined age of menarche and final menstrual period, and history of irregular menses from questionnaires at baseline, and calculated reproductive length from age of menarche and final menstrual period...
July 25, 2016: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/27456304/early-menarche-and-gestational-diabetes-mellitus-at-first-live-birth
#9
Yun Shen, Hui Hu, Brandie D Taylor, Haidong Kan, Xiaohui Xu
OBJECTIVES: To examine the association between early menarche and gestational diabetes mellitus (GDM). METHODS: Data from the National Health and Nutrition Examination Survey 2007-2012 were used to investigate the association between age at menarche and the risk of GDM at first birth among 5914 women. A growth mixture model was used to detect distinctive menarche onset patterns based on self-reported age at menarche. Logistic regression models were then used to examine the associations between menarche initiation patterns and GDM after adjusting for sociodemographic factors, family history of diabetes mellitus, lifetime greatest Body Mass Index, smoking status, and physical activity level...
July 25, 2016: Maternal and Child Health Journal
https://www.readbyqxmd.com/read/27419327/diagnosis-and-treatment-of-polycystic-ovary-syndrome
#10
Tracy Williams, Rami Mortada, Samuel Porter
Polycystic ovary syndrome is the most common endocrinopathy among reproductive-aged women in the United States, affecting approximately 7% of female patients. Although the pathophysiology of the syndrome is complex and there is no single defect from which it is known to result, it is hypothesized that insulin resistance is a key factor. Metabolic syndrome is twice as common in patients with polycystic ovary syndrome compared with the general population, and patients with polycystic ovary syndrome are four times more likely than the general population to develop type 2 diabetes mellitus...
July 15, 2016: American Family Physician
https://www.readbyqxmd.com/read/27345735/reproductive-factors-and-risk-of-type-2-diabetes-in-an-occupational-cohort-of-chinese-women
#11
Aimin Yang, Simin Liu, Ning Cheng, Hongquan Pu, Min Dai, Jiao Ding, Juansheng Li, Haiyan Li, Xiaobin Hu, Xiaowei Ren, Jie He, Tongzhang Zheng, Yana Bai
AIMS: Hormonal milieu has long been known to play an important role in the development of type 2 diabetes (T2D). The aims of this study are to investigate the roles of menstrual and reproductive factors in relation to T2D risk in an occupational cohort of Chinese women; and to explore the role of endogenous estrogen in T2D development. METHODS: We conducted a cross-sectional analysis of baseline data from 16114 women (11051 premenopausal and 5063 postmenopausal) aged ≥20years who participated in the ongoing prospective occupational cohort study...
September 2016: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/27235200/oestradiol-levels-may-differ-between-premenopausal-women-ages-18-50-with-type-1-diabetes-and-matched-controls
#12
Lina Saleh Hassan, Rebecca S Monson, Kirstie K Danielson
BACKGROUND: This study aimed to investigate whether oestradiol differs between premenopausal women with and without type 1 diabetes and whether levels are associated with such factors as age, reproductive history or diabetes management. METHODS: Oestradiol in premenopausal women with type 1 diabetes (n = 89; age = 18-50 years; duration = 13-18 years) and age-matched/race-matched controls without diabetes (n = 76) was collected during a cross-sectional ancillary study of the Wisconsin Diabetes Registry Study, a population-based incident cohort...
May 27, 2016: Diabetes/metabolism Research and Reviews
https://www.readbyqxmd.com/read/27177284/changes-in-the-expression-of-serum-mir-887-5p-in-patients-with-endometrial-cancer
#13
Yan Jiang, Ning Wang, Duo Yin, Yong Kang Li, Li Guo, Li Ping Shi, Xiao Huang
OBJECTIVE: The purpose of the study was to examine whether miR-887-5p could be used as a diagnostic marker for endometrial cancer. METHODS: In the first stage, differentially expressed serum micro-RNAs (miRNAs) in the sera of 50 healthy subjects and 50 patients with endometrial cancer were screened by performing Solexa sequencing. In addition, differential expression of these serum miRNAs in endometrial cancer tissues and adjacent normal tissues from 3 patients with endometrial cancer was examined...
July 2016: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/27149485/association-between-age-at-menarche-and-risk-factors-for-cardiovascular-diseases-in-korean-women-the-2010-to-2013-korea-national-health-and-nutrition-examination-survey
#14
Jong Chul Won, Jae Won Hong, Jung Hyun Noh, Dong-Jun Kim
Early menarche is strongly associated with adulthood obesity; however, the relationship between age at menarche and cardiovascular disease (CVD) in Korean women remains poorly understood. Here, we investigated the association between early menarche and risk factors for developing CVD during adulthood using a nationwide population database.In total, 12,336 women (weighted n = 17,483,406; weighted age, 45.7 years) who participated in the Korean National Health and Nutrition Examination Survey 2010 to 2013 were included in this study...
May 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27075448/assessing-the-genetic-architecture-of-epithelial-ovarian-cancer-histological-subtypes
#15
Gabriel Cuellar-Partida, Yi Lu, Suzanne C Dixon, Peter A Fasching, Alexander Hein, Stefanie Burghaus, Matthias W Beckmann, Diether Lambrechts, Els Van Nieuwenhuysen, Ignace Vergote, Adriaan Vanderstichele, Jennifer Anne Doherty, Mary Anne Rossing, Jenny Chang-Claude, Anja Rudolph, Shan Wang-Gohrke, Marc T Goodman, Natalia Bogdanova, Thilo Dörk, Matthias Dürst, Peter Hillemanns, Ingo B Runnebaum, Natalia Antonenkova, Ralf Butzow, Arto Leminen, Heli Nevanlinna, Liisa M Pelttari, Robert P Edwards, Joseph L Kelley, Francesmary Modugno, Kirsten B Moysich, Roberta B Ness, Rikki Cannioto, Estrid Høgdall, Claus Høgdall, Allan Jensen, Graham G Giles, Fiona Bruinsma, Susanne K Kjaer, Michelle A T Hildebrandt, Dong Liang, Karen H Lu, Xifeng Wu, Maria Bisogna, Fanny Dao, Douglas A Levine, Daniel W Cramer, Kathryn L Terry, Shelley S Tworoger, Meir Stampfer, Stacey Missmer, Line Bjorge, Helga B Salvesen, Reidun K Kopperud, Katharina Bischof, Katja K H Aben, Lambertus A Kiemeney, Leon F A G Massuger, Angela Brooks-Wilson, Sara H Olson, Valerie McGuire, Joseph H Rothstein, Weiva Sieh, Alice S Whittemore, Linda S Cook, Nhu D Le, C Blake Gilks, Jacek Gronwald, Anna Jakubowska, Jan Lubiński, Tomasz Kluz, Honglin Song, Jonathan P Tyrer, Nicolas Wentzensen, Louise Brinton, Britton Trabert, Jolanta Lissowska, John R McLaughlin, Steven A Narod, Catherine Phelan, Hoda Anton-Culver, Argyrios Ziogas, Diana Eccles, Ian Campbell, Simon A Gayther, Aleksandra Gentry-Maharaj, Usha Menon, Susan J Ramus, Anna H Wu, Agnieszka Dansonka-Mieszkowska, Jolanta Kupryjanczyk, Agnieszka Timorek, Lukasz Szafron, Julie M Cunningham, Brooke L Fridley, Stacey J Winham, Elisa V Bandera, Elizabeth M Poole, Terry K Morgan, Ellen L Goode, Joellen M Schildkraut, Celeste L Pearce, Andrew Berchuck, Paul D P Pharoah, Penelope M Webb, Georgia Chenevix-Trench, Harvey A Risch, Stuart MacGregor
Epithelial ovarian cancer (EOC) is one of the deadliest common cancers. The five most common types of disease are high-grade and low-grade serous, endometrioid, mucinous and clear cell carcinoma. Each of these subtypes present distinct molecular pathogeneses and sensitivities to treatments. Recent studies show that certain genetic variants confer susceptibility to all subtypes while other variants are subtype-specific. Here, we perform an extensive analysis of the genetic architecture of EOC subtypes. To this end, we used data of 10,014 invasive EOC patients and 21,233 controls from the Ovarian Cancer Association Consortium genotyped in the iCOGS array (211,155 SNPs)...
July 2016: Human Genetics
https://www.readbyqxmd.com/read/27034774/strategies-and-methods-to-study-female-specific-cardiovascular-health-and-disease-a-guide-for-clinical-scientists
#16
REVIEW
Pamela Ouyang, Nanette K Wenger, Doris Taylor, Janet W Rich-Edwards, Meir Steiner, Leslee J Shaw, Sarah L Berga, Virginia M Miller, Noel Bairey Merz
BACKGROUND: In 2001, the Institute of Medicine's (IOM) report, "Exploring the Biological Contributions to Human Health: Does Sex Matter?" advocated for better understanding of the differences in human diseases between the sexes, with translation of these differences into clinical practice. Sex differences are well documented in the prevalence of cardiovascular (CV) risk factors, the clinical manifestation and incidence of cardiovascular disease (CVD), and the impact of risk factors on outcomes...
2016: Biology of Sex Differences
https://www.readbyqxmd.com/read/26977831/diagnosis-and-management-of-endometrial-cancer
#17
Michael M Braun, Erika A Overbeek-Wager, Robert J Grumbo
Endometrial cancer is the most common gynecologic malignancy. It is the fourth most common cancer in women in the United States after breast, lung, and colorectal cancers. Risk factors are related to excessive unopposed exposure of the endometrium to estrogen, including unopposed estrogen therapy, early menarche, late menopause, tamoxifen therapy, nulliparity, infertility or failure to ovulate, and polycystic ovary syndrome. Additional risk factors are increasing age, obesity, hypertension, diabetes mellitus, and hereditary nonpolyposis colorectal cancer...
March 15, 2016: American Family Physician
https://www.readbyqxmd.com/read/26948305/oral-contraceptive-use-and-prevalence-of-self-reported-glaucoma-or-ocular-hypertension-in-the-united-states
#18
Ye Elaine Wang, Caitlin Kakigi, Diego Barbosa, Travis Porco, Rebecca Chen, Sophia Wang, Yingjie Li, Kuldev Singh, Louis R Pasquale, Shan C Lin
PURPOSE: To investigate the association between oral contraceptive (OC) use and glaucoma prevalence in the United States. DESIGN: Cross-sectional study. PARTICIPANTS: A total of 3406 female participants, aged 40 years or older, from the 2005 to 2008 National Health and Nutrition Examination Survey, who reported a presence or absence of glaucoma or ocular hypertension completed both the vision and the reproductive health questionnaires and underwent eye examinations...
April 2016: Ophthalmology
https://www.readbyqxmd.com/read/26879303/diabetes-and-menopause
#19
REVIEW
Carrie A Karvonen-Gutierrez, Sung Kyun Park, Catherine Kim
During menopause, women's body composition, sex hormone profile, and metabolic profile may change dramatically. In this review, we summarize studies examining whether the menopausal transition and physiologic factors characterizing the transition are associated with increased risk of diabetes. We review the evidence for estrogen therapy and diabetes risk and studies examining the relationship between diabetes and menarche, which represents an extension of the reproductive life span at the opposite end of the age spectrum...
April 2016: Current Diabetes Reports
https://www.readbyqxmd.com/read/26813668/age-at-menarche-and-risk-of-gestational-diabetes-mellitus-a-prospective-cohort-study-among-27-482-women
#20
Liwei Chen, Shanshan Li, Chunyan He, Yeyi Zhu, Germaine M Buck Louis, Edwina Yeung, Frank B Hu, Cuilin Zhang
OBJECTIVE: To examine the association between age at menarche and risk of gestational diabetes mellitus (GDM). RESEARCH DESIGN AND METHODS: A prospective cohort study of 42,109 eligible pregnancies from 27,482 women in the Nurses' Health Study II. RESULTS: The adjusted risk ratios for GDM across the age at menarche categories (≤11, 12, 13, and ≥14 years) were 1.34 (95% CI 1.14-1.58), 1.13 (0.97-1.31), 1.11 (0.95-1.29), and 1.00 (referent; P for trend = 0...
March 2016: Diabetes Care
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