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Menarche and diabetes

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https://www.readbyqxmd.com/read/29697830/menstrual-dysfunction-in-girls-from-the-treatment-options-for-type-2-diabetes-in-adolescents-and-youth-today-study
#1
Megan M Kelsey, Barbara H Braffett, Mitchell E Geffner, Lynne L Levitsky, Sonia Caprio, Siripoom V McKay, Rachana Shah, Jennifer E Sprague, Silva A Arslanian
Context: Little is known about reproductive function in girls with youth-onset type 2 diabetes. Objectives: To characterize girls with irregular menses, and effects of glycemic treatments on menses and sex steroids in the Treatment Options for Type 2 Diabetes in Youth (TODAY) study. Design: Differences in demographic, metabolic, and hormonal characteristics between regular vs. irregular menses groups were tested; treatment group (metformin +/- rosiglitazone, metformin + lifestyle) effect on menses and sex steroids over time in the study was assessed...
April 24, 2018: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29696756/female-reproductive-history-and-risk-of-type-2-diabetes-a-prospective-analysis-of-126-721-women
#2
Nirmala Pandeya, Rachel R Huxley, Hsin-Fang Chung, Annette J Dobson, Diana Kuh, Rebecca Hardy, Janet E Cade, Darren C Greenwood, Graham G Giles, Fiona Bruinsma, Panayotes Demakakos, Mette Kildevaeld Simonsen, Hans-Olov Adami, Elisabete Weiderpass, Gita D Mishra
AIMS: Female reproductive history has been inconsistently associated with risk of type 2 diabetes. We examined the prospective associations between aspects of a woman's reproductive history and incident diabetes. METHODS: This study pooled 126,721 middle-aged women's individual data from eight cohort studies contributing to the International Collaboration for a Life Course Approach to Reproductive Health and Chronic Disease Events (InterLACE). Associations between age at menarche, age at first birth, parity and menopausal status with incident diabetes were examined using generalized linear mixed models with binomial distribution and robust variance...
April 25, 2018: Diabetes, Obesity & Metabolism
https://www.readbyqxmd.com/read/29682210/age-at-menarche-and-risks-of-gestational-diabetes-mellitus-a-meta-analysis-of-prospective-studies
#3
Ya Xiao, Ruixue Chen, Minghao Chen, Anling Luo, Dayi Chen, Qiuer Liang, Yunfei Cai, Liguo Chen, Xiaoshan Zhao
Background: Accumulating evidence suggests that early menarche is associated with adult obesity, which in turn may increase the risk of insulin resistance and hyperglycemia. However, the relation of menarcheal age with gestational diabetes mellitus (GDM) remains inconsistent across studies. The objective of this meta-analysis was to evaluate the association between age at menarche and GDM risk. Materials and Methods: We searched Medline (PubMed), Embase, Web of Knowledge and the Cochrane library through the end of May 2017...
March 30, 2018: Oncotarget
https://www.readbyqxmd.com/read/29667360/menstrual-and-reproductive-factors-and-type-2-diabetes-risk-the-japan-public-health-center-based-prospective-study
#4
Akiko Nanri, Tetsuya Mizoue, Mitsuhiko Noda, Atsushi Goto, Norie Sawada, Shoichiro Tsugane
AIMS/INTRODUCTION: Menstrual and reproductive factors, including age at menarche, parity, and breastfeeding, have been linked to type 2 diabetes risk. We prospectively investigated the association between these factors and type 2 diabetes risk in a large Japanese cohort. MATERIALS AND METHODS: Participants were 37,511 women aged 45-75 years who participated in the baseline (1990-1993), second (1995-1998), and third surveys (2000-2003) of the Japan Public Health Center-based Prospective Study and who had no history of diabetes at the second survey...
April 18, 2018: Journal of Diabetes Investigation
https://www.readbyqxmd.com/read/29575815/impact-of-age-at-menarche-on-obesity-and-glycemic-control-in-japanese-patients-with-type-2-diabetes-fukuoka-diabetes-registry
#5
Akiko Sumi, Masanori Iwase, Udai Nakamura, Hiroki Fujii, Toshiaki Ohkuma, Hitoshi Ide, Tamaki Jodai-Kitamura, Yuji Komorita, Masahito Yoshinari, Takanari Kitazono
AIMS/INTRODUCTION: A younger age at menarche is associated with obesity and type 2 diabetes in adult life. The impact of early onset menarche on obesity and glycemic control in type 2 diabetes has not been investigated. This study examined the relationship between age at menarche and obesity and glycemic control in type 2 diabetes. MATERIALS AND METHODS: A total of 2,133 patients with type 2 diabetes aged ≥20 years were divided into groups according to age at menarche (≤11 years, 12 years, 13 years, 14 years, and ≥15 years)...
March 25, 2018: Journal of Diabetes Investigation
https://www.readbyqxmd.com/read/29558518/risk-factors-for-type-2-diabetes-mellitus-an-exposure-wide-umbrella-review-of-meta-analyses
#6
Vanesa Bellou, Lazaros Belbasis, Ioanna Tzoulaki, Evangelos Evangelou
BACKGROUND: Type 2 diabetes mellitus (T2DM) is a global epidemic associated with increased health expenditure, and low quality of life. Many non-genetic risk factors have been suggested, but their overall epidemiological credibility has not been assessed. METHODS: We searched PubMed to capture all meta-analyses and Mendelian randomization studies for risk factors of T2DM. For each association, we estimated the summary effect size, its 95% confidence and prediction interval, and the I2 metric...
2018: PloS One
https://www.readbyqxmd.com/read/29556913/age-at-menarche-and-the-risk-of-gestational-diabetes-mellitus-a-systematic-review-and-meta-analysis
#7
Xiaoting Sun, Lili Yang, Jiexue Pan, Haiyan Yang, Yanting Wu, Zimiao Chen, Xia Chen, Liangshan Mu
PURPOSE: Epidemiological studies had demonstrated that early age at menarche increased the risk of type 2 diabetes (T2DM), and gestational diabetes mellitus (GDM) shares many risk factors and features with T2DM. Thus, age at menarche may be a potential factor in the development of GDM. The aim of this study was to assess the association between age at menarche and the risk of gestational diabetes mellitus. METHODS: The databases of PubMed, Embase, Web of Science and Cochrane Library were searched up to June 2017...
March 20, 2018: Endocrine
https://www.readbyqxmd.com/read/29551993/gonadal-hormones-and-retinal-disorders-a-review
#8
REVIEW
Raffaele Nuzzi, Simona Scalabrin, Alice Becco, Giancarlo Panzica
Aim: Gonadal hormones are essential for reproductive function, but can act on neural and other organ systems, and are probably the cause of the large majority of known sex differences in function and disease. The aim of this review is to provide evidence for this hypothesis in relation to eye disorders and to retinopathies in particular. Methods: Epidemiological studies and research articles were reviewed. Results: Analysis of the biological basis for a relationship between eye diseases and hormones showed that estrogen, androgen, and progesterone receptors are present throughout the eye and that these steroids are locally produced in ocular tissues...
2018: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/29452776/women-specific-risk-factors-for-heart-failure-a-genetic-approach
#9
REVIEW
Jet van der Kemp, Yvonne T van der Schouw, Folkert W Asselbergs, N Charlotte Onland-Moret
Heart failure is a complex disease, which is presented differently by men and women. Several studies have shown that reproductive factors, such as age at natural menopause, parity and polycystic ovarian syndrome (PCOS), may play a role in the development of heart failure. Shared genetics may provide clues to underlying mechanisms; however, this has never been examined. Therefore, the aim of the current study was to explore whether any reproductive factor is potentially related to heart failure in women, based on genetic similarities...
March 2018: Maturitas
https://www.readbyqxmd.com/read/29240516/association-between-duration-of-reproductive-years-and-metabolic-syndrome
#10
Yon Chul Park, Tae Sic Lee, Hee-Taik Kang, Eun Suk Cho, Jai Soon Kim, Yoo Jung Hwang, Jong-Koo Kim
BACKGROUND: The incidence of metabolic syndrome (MetS) has gradually increased in recent years. MetS has been associated with age at menarche and menopause; however, the association between MetS and the reproductive span remains unclear. MATERIALS AND METHODS: This study examined MetS and the reproductive span among 1,214 participants of the 2014 Korea National Health and Nutrition Examination Surveys, a stratified, complex, multistage, probability cluster survey conducted by the Division of Chronic Disease Surveillance of the Korea Center for Disease Control and Prevention since 1998...
December 14, 2017: Journal of Women's Health
https://www.readbyqxmd.com/read/29204256/reproductive-disturbances-among-saudi-adolescent-girls-and-young-women-with-type-1-diabetes-mellitus
#11
Rim Braham, Asirvatham Alwin Robert, Maha Ali Musallam, Abdulaziz Alanazi, Nawaf Bin Swedan, Mohamed Abdulaziz Al Dawish
AIM: To identify reproductive disturbances among adolescent girls and young women with type 1 diabetes mellitus (T1DM) in Saudi Arabia. METHODS: This cross sectional study was conducted among 102 female with T1DM, (aged 13-29 years) who attended the Diabetes Clinic at Diabetes Treatment Center, Prince Sultan Military Medical City, Saudi Arabia between April 2015 to March 2016. Clinical history, anthropometric characteristics and reproductive disturbance were collected through a questionnaire...
November 15, 2017: World Journal of Diabetes
https://www.readbyqxmd.com/read/29150167/reproductive-factors-in-relation-to-heart-failure-in-women-a-systematic-review
#12
REVIEW
Renee Bolijn, N Charlotte Onland-Moret, Folkert W Asselbergs, Yvonne T van der Schouw
BACKGROUND: The biological mechanisms underlying the sex-related differences in risk of heart failure are still not well understood. The aim of this review was to provide an overview of the current evidence on the association between reproductive factors and risk of heart failure in women. METHODS: A systematic review of the literature was conducted. PubMed and Embase databases were searched for publications on the following reproductive factors as potential risk factors for heart failure in women: age at menarche, duration and frequency of the menstrual cycle, reproductive lifespan, use of contraception, polycystic ovarian syndrome (PCOS), pregnancy characteristics (e...
December 2017: Maturitas
https://www.readbyqxmd.com/read/29128916/cardiometabolic-risk-in-pcos-more-than-a-reproductive-disorder
#13
REVIEW
Laura C Torchen
PURPOSE OF REVIEW: Polycystic ovary syndrome (PCOS) is diagnosed by its characteristic reproductive features. However, PCOS is also associated with metabolic abnormalities, including insulin resistance and β-cell dysfunction. The severity of these abnormalities varies according to the reproductive phenotype, with the so-called NIH or classic phenotype conferring the greatest metabolic risk. The increased risk for type 2 diabetes (T2D) is well established among affected women with the NIH phenotype, but whether PCOS also confers an increased risk for cardiovascular events remains unknown...
November 11, 2017: Current Diabetes Reports
https://www.readbyqxmd.com/read/29069258/early-menarche-and-teenager-pregnancy-as-risk-factors-for-morbid-obesity-among-reproductive-age-women-a-case-control-study
#14
Amanda Gonçalves Neves, Karina Tamy Kasawara, Ana Carolina Godoy-Miranda, Flávio Hideki Oshika, Elinton Adami Chaim, Fernanda Garanhani Surita
OBJECTIVES: The aim of this study was to evaluate potential risk factors, including non-communicable diseases, for morbid obesity in women between 20 and 49 years of age. METHODS: We performed a case-control study with 110 morbidly obese women and 110 women with adequate weight who were matched by age and with a 1:1 case to control ratio. All women were between 20 to 49 years old and non-menopausal. Possible risk factors were evaluated through a self-report questionnaire assessing socio-demographic, obstetric and gynecological characteristics, presence of non-communicable diseases and habits...
October 2017: Clinics
https://www.readbyqxmd.com/read/28927079/new-use-of-microsatellite-instability-analysis-in-endometrial-cancer
#15
Haruko Kunitomi, Kouji Banno, Megumi Yanokura, Takashi Takeda, Moito Iijima, Kanako Nakamura, Miho Iida, Masataka Adachi, Keiko Watanabe, Yusuke Matoba, Yusuke Kobayashi, Eiichiro Tominaga, Daisuke Aoki
The increasing incidence of obesity and diabetes due to changes in diet, earlier menarche, delayed menopause, late marriage, and declining birth rate have resulted in an increase in the number of endometrial cancer cases over the last few decades. Although surgical therapy is sufficient for early endometrial cancer, there is no effective therapy for patients with advanced and recurrent endometrial cancer. The oncogenic mechanism of endometrial cancer involves microsatellite instability (MSI) caused by dysfunction of DNA mismatch repair genes in 30% of patients...
September 2017: Oncology Letters
https://www.readbyqxmd.com/read/28746163/the-potential-contribution-of-dietary-factors-to-breast-cancer-prevention
#16
Niva Shapira
Breast cancer (BC), the leading cancer in women, is increasing in prevalence worldwide, concurrent with western metabolic epidemics, that is, obesity, metabolic syndrome, and diabetes, and shares major risk factors with these diseases. The corresponding potential for nutritional contributions toward BC prevention is reviewed and related to critical stages in the life cycle and their implications for carcinogenic and pathometabolic trajectories. BC initiation potentially involves diet-related pro-oxidative, inflammatory, and procarcinogenic processes, that interact through combined lipid/fatty acid peroxidation, estrogen metabolism, and related DNA-adduct/depurination/mutation formation...
September 2017: European Journal of Cancer Prevention
https://www.readbyqxmd.com/read/28736691/prevalence-and-risk-factors-of-osteoporosis-among-jordanian-postmenopausal-women-attending-the-national-center-for-diabetes-endocrinology-and-genetics-in-jordan
#17
Dana Hyassat, Taghreed Alyan, Hashem Jaddou, Kamel M Ajlouni
To assess the prevalence of osteoporosis and osteopenia among Jordanian postmenopausal women attending the National Center for Diabetes, Endocrinology, and Genetics (NCDEG), and to determine the potential associated risk factors. A cross-sectional study was conducted at (NCDEG) in Amman, Jordan. A total of 1079 Jordanian postmenopausal women aged between 45 and 84 years were included in this study that was conducted during the period between April 2013 and December 2014. All patients underwent bone mineral density measurement through dual-energy X-ray absorptiometry (DEXA) scan...
2017: BioResearch Open Access
https://www.readbyqxmd.com/read/28605451/age-at-menarche-and-incidence-of-diabetes-a-prospective-study-of-300-000-women-in-china
#18
Ling Yang, Liming Li, Sanne A E Peters, Robert Clarke, Yu Guo, Yiping Chen, Zheng Bian, Paul Sherliker, Jiyuan Yin, Zhenzhu Tang, Chunmei Wang, Xiaohuan Wang, Libo Zhang, Mark Woodward, Zhengming Chen
Previous studies of predominantly Western populations have reported inconsistent associations between age at menarche and risk of diabetes. We examined this relationship among Chinese women, who generally experience menarche at a later age than Western women. In 2004-2008, China Kadoorie Biobank recruited 302,632 women aged 30-79 years from 10 areas across China, and recorded 5,391 incident cases of diabetes during 7 years of follow-up among 270,345 women without baseline diabetes, cardiovascular disease or cancer...
February 1, 2018: American Journal of Epidemiology
https://www.readbyqxmd.com/read/28601624/age-at-menarche-and-cardiovascular-risk-factors-using-mendelian-randomization-in-the-guangzhou-biobank-cohort-study
#19
Shiu Lun Au Yeung, Chaoqiang Jiang, Kar Keung Cheng, Lin Xu, Weisen Zhang, Tai Hing Lam, Gabriel Matthew Leung, C Mary Schooling
Observational studies show earlier age at menarche associated with higher risk of cardiovascular disease although these studies could be confounded by childhood obesity or childhood socioeconomic position. We tested the hypothesis that earlier age at menarche is associated with poorer cardiovascular risk factors using a Mendelian randomization design. We conducted a Mendelian randomization study in a large Southern Chinese cohort, the Guangzhou Biobank Cohort Study (n=12,279), to clarify the causal role of menarche in cardiovascular disease risk factors including blood pressure, lipids, fasting glucose, adiposity and type 2 diabetes...
August 2017: Preventive Medicine
https://www.readbyqxmd.com/read/28338812/association-between-age-at-menarche-and-gestational-diabetes-mellitus-the-australian-longitudinal-study-on-women-s-health
#20
Danielle A J M Schoenaker, Gita D Mishra
In this study, we aimed to examine the association between age at menarche and gestational diabetes mellitus (GDM). Data were from 4,749 women participating in the Australian Longitudinal Study on Women's Health between 2000 and 2012. Age at menarche was reported at baseline in 2000 when women were aged 22-27 years. During 12 years of follow-up, information on GDM diagnosis was obtained for each live birth. Log-binomial regression analysis was used to estimate relative risks and 95% confidence intervals. Analyses adjusted for mother's highest completed educational qualification, nulliparity, polycystic ovary syndrome, physical activity, and body mass index...
April 1, 2017: American Journal of Epidemiology
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