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Menarche and diabetes

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https://www.readbyqxmd.com/read/28927079/new-use-of-microsatellite-instability-analysis-in-endometrial-cancer
#1
Haruko Kunitomi, Kouji Banno, Megumi Yanokura, Takashi Takeda, Moito Iijima, Kanako Nakamura, Miho Iida, Masataka Adachi, Keiko Watanabe, Yusuke Matoba, Yusuke Kobayashi, Eiichiro Tominaga, Daisuke Aoki
The increasing incidence of obesity and diabetes due to changes in diet, earlier menarche, delayed menopause, late marriage, and declining birth rate have resulted in an increase in the number of endometrial cancer cases over the last few decades. Although surgical therapy is sufficient for early endometrial cancer, there is no effective therapy for patients with advanced and recurrent endometrial cancer. The oncogenic mechanism of endometrial cancer involves microsatellite instability (MSI) caused by dysfunction of DNA mismatch repair genes in 30% of patients...
September 2017: Oncology Letters
https://www.readbyqxmd.com/read/28746163/the-potential-contribution-of-dietary-factors-to-breast-cancer-prevention
#2
Niva Shapira
Breast cancer (BC), the leading cancer in women, is increasing in prevalence worldwide, concurrent with western metabolic epidemics, that is, obesity, metabolic syndrome, and diabetes, and shares major risk factors with these diseases. The corresponding potential for nutritional contributions toward BC prevention is reviewed and related to critical stages in the life cycle and their implications for carcinogenic and pathometabolic trajectories. BC initiation potentially involves diet-related pro-oxidative, inflammatory, and procarcinogenic processes, that interact through combined lipid/fatty acid peroxidation, estrogen metabolism, and related DNA-adduct/depurination/mutation formation...
September 2017: European Journal of Cancer Prevention
https://www.readbyqxmd.com/read/28736691/prevalence-and-risk-factors-of-osteoporosis-among-jordanian-postmenopausal-women-attending-the-national-center-for-diabetes-endocrinology-and-genetics-in-jordan
#3
Dana Hyassat, Taghreed Alyan, Hashem Jaddou, Kamel M Ajlouni
To assess the prevalence of osteoporosis and osteopenia among Jordanian postmenopausal women attending the National Center for Diabetes, Endocrinology, and Genetics (NCDEG), and to determine the potential associated risk factors. A cross-sectional study was conducted at (NCDEG) in Amman, Jordan. A total of 1079 Jordanian postmenopausal women aged between 45 and 84 years were included in this study that was conducted during the period between April 2013 and December 2014. All patients underwent bone mineral density measurement through dual-energy X-ray absorptiometry (DEXA) scan...
2017: BioResearch Open Access
https://www.readbyqxmd.com/read/28605451/age-at-menarche-and-incidence-of-diabetes-a-prospective-study-of-300-000-women-in-china
#4
Ling Yang, Liming Li, Sanne A E Peters, Robert Clarke, Yu Guo, Yiping Chen, Zheng Bian, Paul Sherliker, Jiyuan Yin, Zhenzhu Tang, Chunmei Wang, Xiaohuan Wang, Libo Zhang, Mark Woodward, Zhengming Chen
Previous studies of mostly Western populations have reported inconsistent associations between age at menarche and risk of diabetes. We examined such associations among Chinese women who tend to have later menarche age than women in West. China Kadoorie Biobank recruited 302,632 women aged 30-79 years from 10 areas across China in 2004-8, recording 5,391 incident cases of diabetes during 7-years follow-up among 270,345 women without diabetes, cardiovascular disease or cancer at baseline. Cox regression models yielded adjusted hazard ratios (HRs) for incident diabetes associated with age at menarche...
June 9, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/28601624/age-at-menarche-and-cardiovascular-risk-factors-using-mendelian-randomization-in-the-guangzhou-biobank-cohort-study
#5
Shiu Lun Au Yeung, Chaoqiang Jiang, Kar Keung Cheng, Lin Xu, Weisen Zhang, Tai Hing Lam, Gabriel Matthew Leung, C Mary Schooling
Observational studies show earlier age at menarche associated with higher risk of cardiovascular disease although these studies could be confounded by childhood obesity or childhood socioeconomic position. We tested the hypothesis that earlier age at menarche is associated with poorer cardiovascular risk factors using a Mendelian randomization design. We conducted a Mendelian randomization study in a large Southern Chinese cohort, the Guangzhou Biobank Cohort Study (n=12,279), to clarify the causal role of menarche in cardiovascular disease risk factors including blood pressure, lipids, fasting glucose, adiposity and type 2 diabetes...
August 2017: Preventive Medicine
https://www.readbyqxmd.com/read/28338812/association-between-age-at-menarche-and-gestational-diabetes-mellitus-the-australian-longitudinal-study-on-women-s-health
#6
Danielle A J M Schoenaker, Gita D Mishra
In this study, we aimed to examine the association between age at menarche and gestational diabetes mellitus (GDM). Data were from 4,749 women participating in the Australian Longitudinal Study on Women's Health between 2000 and 2012. Age at menarche was reported at baseline in 2000 when women were aged 22-27 years. During 12 years of follow-up, information on GDM diagnosis was obtained for each live birth. Log-binomial regression analysis was used to estimate relative risks and 95% confidence intervals. Analyses adjusted for mother's highest completed educational qualification, nulliparity, polycystic ovary syndrome, physical activity, and body mass index...
April 1, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/28264804/earlier-menarche-is-linked-to-increased-risk-of-gestational-diabetes-study-finds
#7
Jacqui Wise
No abstract text is available yet for this article.
March 5, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28161369/early-age-at-menarche-and-gestational-diabetes-mellitus-risk-results-from-the-healthy-baby-cohort-study
#8
H Li, L Shen, L Song, B Liu, X Zheng, S Xu, Y Wang
AIM: Early age at menarche has been reported to increase type 2 diabetes risk, but little is known of its impact on gestational diabetes mellitus (GDM) risk. The aim of this study was to examine the association between age at menarche and plasma glucose levels as well as GDM risk. METHODS: A total of 6900 pregnant women from the Healthy Baby Cohort Study were included in our analysis. Age at menarche was self-reported and categorized into five groups (9-11, 12, 13, 14 and 15-18 years of age)...
February 1, 2017: Diabetes & Metabolism
https://www.readbyqxmd.com/read/28112874/duration-of-puberty-in-preterm-girls
#9
L L Hui, H S Lam, G M Leung, C M Schooling
OBJECTIVES: Preterm birth is associated with altered pubertal timing, but the effect on pubertal duration has rarely been assessed. Here, we tested the hypothesis that preterm birth is associated with shorter duration of puberty among girls in Hong Kong where preterm birth has little social patterning. METHODS: In the population-representative Chinese birth cohort "Children of 1997", we used multivariable linear regression to assess the association of preterm status (≤36 completed gestational weeks, n = 170; term birth 37-42 gestational weeks, n = 3476) with duration of puberty, adjusted for parent's highest education, mother's place of birth, maternal smoking during pregnancy, gestational diabetes, preeclampsia, and mother's age of menarche...
July 8, 2017: American Journal of Human Biology: the Official Journal of the Human Biology Council
https://www.readbyqxmd.com/read/28041589/ovarian-aging-in-women-with-diabetes-an-overview
#10
REVIEW
Melissa F Wellons, Juliana J Matthews, Catherine Kim
Type 2 diabetes is a global epidemic, and the prevalence and incidence of type 1 diabetes are increasing. The negative effects of diabetes on kidneys, nerves, and vessels are well established. The effect of diabetes on reproductive function is less well understood, but important to characterize, given the increasing numbers of young women with diabetes. In this review, we summarize the available literature on how women with diabetes experience ovarian aging, from menarche to menopause. We report that women with type 1 diabetes appear more likely to have ovarian dysfunction, manifested by delayed menses, menstrual irregularities, and possibly earlier menopause...
February 2017: Maturitas
https://www.readbyqxmd.com/read/27974911/the-etiopathogenesis-of-uterine-fibromatosis
#11
REVIEW
L Manta, N Suciu, O Toader, R M Purcărea, A Constantin, F Popa
Uterine fibroids or uterine leiomyomas are the most common benign tumors of the uterus among women of fertile age, while the etiology is still incompletely elucidated. The occurrence and development of the fibromatosis may be related to certain risk factors and genic mechanisms, although the exact causes are not yet fully known. The development of uterine fibroids is correlated not only with the metabolism and with the level of female sexual hormones, estrogen, and progesterone, but also with the number of these hormone receptors expressed on the surface of the myometrium...
January 2016: Journal of Medicine and Life
https://www.readbyqxmd.com/read/27899085/oestradiol-levels-and-superoxide-dismutase-activity-in-age-related-cataract-a-case-control-study
#12
Dragana Škiljić, Staffan Nilsson, Anne Petersen, Jan-Olof Karlsson, Anders Behndig, Lada Kalaboukhova, Madeleine Zetterberg
BACKGROUND: It has been suggested that the higher prevalence of cataract in women is caused by a withdrawal effect of oestrogen at menopause. In vitro studies have demonstrated protection of serum oestradiol (E2) against oxidative stress through upregulation of antioxidant enzymes, including superoxide dismutase (SOD). The purpose of the present study was to investigate E2 levels and SOD erythrocyte activity in patients with age-related cataract. METHODS: The studied subjects consisted of 103 patients with age-related cataract and 22 controls...
November 29, 2016: BMC Ophthalmology
https://www.readbyqxmd.com/read/27798047/common-diseases-as-determinants-of-menopausal-age
#13
Jingmei Li, Mikael Eriksson, Kamila Czene, Per Hall, Kenny A Rodriguez-Wallberg
STUDY QUESTION: Can the diagnosis of common diseases before menopause influence age at natural menopause (ANM) onset? SUMMARY ANSWER: Polycystic ovary syndrome (PCOS) and depression were observed to delay menopause. WHAT IS KNOWN ALREADY: It has been observed that women who undergo early menopause experience a higher burden of health problems related to metabolic syndromes, heart disease and depression, but whether ANM can be influenced by common adult diseases has not been studied extensively...
December 2016: Human Reproduction
https://www.readbyqxmd.com/read/27765126/-association-and-interaction-between-age-at-menarche-and-risk-of-diabetes-in-adult-women
#14
H Wang, R Y Hu, J M Zhong, Y J Qian, C M Wang, K X Xie, L L Chen, Z Bian, Y Guo, M Yu, Z M Chen, L M Li
Objective: To explore the associations between age at menarche and diabetes in adult women. Methods: We analyzed the baseline data of 32 364 female participants who were aged 30-79 years and had been enrolled into China Kadoorie Biobank (CKB) study from Tongxiang, Zhejiang province. Multiple logistic regression analysis were used to investigate the putative associations after adjusting for potential confounders. Variables of menarche age and others were added to the logistic regression model to evaluate the multiplicative interaction, respectively...
October 10, 2016: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/27721839/effects-of-early-menarche-on-physical-and-psychosocial-health-problems-in-adolescent-girls-and-adult-women
#15
REVIEW
Jae-Ho Yoo
The menarcheal age of Korean women has been rapidly decreasing for the last 50 years, and the average menarcheal age of women born in the 1990s is approaching 12.6 years. In addition, interest in early puberty has been increasing recently owing to the rapid increase in precocious puberty. Generally, out of concern for short stature and early menarche, idiopathic central precocious puberty in female adolescents is treated with gonadotropin-releasing hormone analogs. Studies to date have described the association between early menarche and psychosocial problems such as delinquency and risky sexual behavior, as well as physical health problems such as obesity, diabetes, cardiovascular diseases, and breast cancer throughout the lifespan of women...
September 2016: Korean Journal of Pediatrics
https://www.readbyqxmd.com/read/27699734/-overview-of-endometrial-cancer
#16
Chia-Chun Li, Tsui-Hsia Feng
Endometrial cancer is the most common gynecological cancer and the sixth most common cancer among women in Taiwan. Risk factors for endometrial cancer include obesity, long-term estrogen replacement therapy, diabetes mellitus, hypertension, nulliparty, early age at menarche, late age at menopause, and tamoxifen therapy. Most women with endometrial cancer exhibit abnormal uterine bleeding. Endometrial cancer is often diagnosed at stage I. Surgery alone is the primary treatment for stage I endometrial cancer...
October 2016: Hu Li za Zhi the Journal of Nursing
https://www.readbyqxmd.com/read/27621257/the-interlace-study-design-data-harmonization-and-characteristics-across-20-studies-on-women-s-health
#17
Gita D Mishra, Hsin-Fang Chung, Nirmala Pandeya, Annette J Dobson, Lee Jones, Nancy E Avis, Sybil L Crawford, Ellen B Gold, Daniel Brown, Lynette L Sievert, Eric Brunner, Janet E Cade, Victoria J Burley, Darren C Greenwood, Graham G Giles, Fiona Bruinsma, Alissa Goodman, Kunihiko Hayashi, Jung Su Lee, Hideki Mizunuma, Diana Kuh, Rachel Cooper, Rebecca Hardy, Carla Makhlouf Obermeyer, Kathryn A Lee, Mette Kildevæld Simonsen, Toyoko Yoshizawa, Nancy F Woods, Ellen S Mitchell, Mark Hamer, Panayotes Demakakos, Sven Sandin, Hans-Olov Adami, Elisabete Weiderpass, Debra Anderson
OBJECTIVES: The International Collaboration for a Life Course Approach to Reproductive Health and Chronic Disease Events (InterLACE) project is a global research collaboration that aims to advance understanding of women's reproductive health in relation to chronic disease risk by pooling individual participant data from several cohort and cross-sectional studies. The aim of this paper is to describe the characteristics of contributing studies and to present the distribution of demographic and reproductive factors and chronic disease outcomes in InterLACE...
October 2016: Maturitas
https://www.readbyqxmd.com/read/27546362/serum-soluble-lectin-like-oxidized-low-density-lipoprotein-receptor-1-levels-in-patients-with-restless-legs-syndrome
#18
G Halac, E Kilic, M A Cikrikcioglu, K Celik, A Toprak-Erek, S Keskin, I Gultepe, R S Celik, N Ozaras, A Yildiz, S Aydin, O Akan, C Karatoprak, Y Sekin, T Asil
OBJECTIVE: The aim of this study was to assess the predisposition for atherosclerosis in patients with RLS through serum sLOX-1 (serum Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1) measurements. BACKGROUND: Recent epidemiological studies have suggested an association of RLS with certain chronic conditions such as diabetes mellitus (DM), obesity, hypertension (HT), and hyperlipidemia. LOX-1 is expressed in endothelial cells, macrophages, and in smooth muscle cells under the effect of proatherogenic conditions...
2016: Bratislavské Lekárske Listy
https://www.readbyqxmd.com/read/27465714/reproductive-history-and-risk-of-type-2-diabetes-mellitus-in-postmenopausal-women-findings-from-the-women-s-health-initiative
#19
Erin S LeBlanc, Kristopher Kapphahn, Haley Hedlin, Manisha Desai, Nisha I Parikh, Simin Liu, Donna R Parker, Matthew Anderson, Vanita Aroda, Shannon Sullivan, Nancy F Woods, Molly E Waring, Cora E Lewis, Marcia Stefanick
OBJECTIVE: The aim of the study was to understand the association between women's reproductive history and their risk of developing type 2 diabetes. We hypothesized that characteristics signifying lower cumulative endogenous estrogen exposure would be associated with increased risk. METHODS: Prospective cohort analysis of 124,379 postmenopausal women aged 50 to 79 years from the Women's Health Initiative (WHI). We determined age of menarche and final menstrual period, and history of irregular menses from questionnaires at baseline, and calculated reproductive length from age of menarche and final menstrual period...
January 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/27456304/early-menarche-and-gestational-diabetes-mellitus-at-first-live-birth
#20
Yun Shen, Hui Hu, Brandie D Taylor, Haidong Kan, Xiaohui Xu
OBJECTIVES: To examine the association between early menarche and gestational diabetes mellitus (GDM). METHODS: Data from the National Health and Nutrition Examination Survey 2007-2012 were used to investigate the association between age at menarche and the risk of GDM at first birth among 5914 women. A growth mixture model was used to detect distinctive menarche onset patterns based on self-reported age at menarche. Logistic regression models were then used to examine the associations between menarche initiation patterns and GDM after adjusting for sociodemographic factors, family history of diabetes mellitus, lifetime greatest Body Mass Index, smoking status, and physical activity level...
March 2017: Maternal and Child Health Journal
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