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Dog pet therapy

Pamela J Schreiner
Animals interact with humans in multiple ways, including as therapy and service animals, commercially as livestock, as wildlife, and in zoos. But the most common interaction is as companion animals in our homes, with an estimated 180 million cats and dogs living in US households. While pet ownership has been reported to have many health benefits, the findings are inconsistent. Cardiovascular risk factors such as lipids, glucose, obesity, and heart rate variability have improved, worsened, or remained the same in the limited number of studies considering companion animals...
February 2016: Current Cardiovascular Risk Reports
Corri B Levine, Julie Bayle, Vincent Biourge, Joseph J Wakshlag
BACKGROUND: Adjunctive use of nutraceuticals in human cancer has shown promise, but little work has been done in canine neoplasia. Previous human research has shown that polyphenols and carotenoids can target multiple pathways in vitro and in vivo. These compounds could synergize or antagonize with currently used chemotherapies, either increasing or decreasing the effectiveness of these drugs. Considering the routine and well controlled feeding practices of most dogs, the use of nutraceuticals incorporated into pet food is attractive, pending proof that the extracts are able to improve remission rates...
2016: BMC Veterinary Research
M G Ribeiro, M C F Lima, M M J Franco, J Megid, L M Soares, L H A Machado, M Miyata, F R Pavan, M B Heinemann, A F Souza Filho, G H B Lara, O C Sanches, C D C Sanches, F J P Listoni, A C Paes
This report describes a fatal case of a pet dog with major enteric signs owned by a family that has experienced cases of pulmonary tuberculosis (TB) in the household. Clinical and epidemiological aspects, imaging data, microbiological, haematological and histopathological examinations were assessed to diagnosis of disease. gyrB-RFLP, spoligotyping and MIRU-VNTR allowed molecular detection of M. tuberculosis strain from S family. The resazurin microtiter assay indicated that all isolates were resistant to isoniazid, ethambutol, ciprofloxacin, ofloxacin, streptomycin and amikacin...
June 30, 2016: Transboundary and Emerging Diseases
R Timothy Bentley, Atique U Ahmed, Amy B Yanke, Aaron A Cohen-Gadol, Mahua Dey
With the median survival of 14.6 months following best available standard of care, malignant gliomas (MGs) remain one of the biggest therapeutic challenges of the modern time. Although the last several decades have witnessed tremendous advancement in our understanding of MG and evolution of many successful preclinical therapeutic strategies, even the most successful preclinical therapeutic strategies often fail to cross the phase I/II clinical trial threshold. One of the significant, but less commonly discussed, barriers in developing effective glioma therapy is the lack of a robust preclinical model...
June 13, 2016: Neuro-oncology
Brittany Heggem-Perry, Maureen McMichael, Mauria O'Brien, Clara Moran
Bromethalin is a central nervous system toxin currently incorporated into several different rodenticides. In 2008, the EPA requested that manufacturers phase out second-generation anticoagulant rodenticides. In response, manufacturers began to increase production of bromethalin-based rodenticides. It is likely that pet exposure to bromethalin will increase in the future. Bromethalin has no known antidote and tends to deposit in fat. Intravenous lipid emulsions (ILEs) are being used with increasing frequency in both human and veterinary medicine to treat numerous acute systemic toxicities...
July 2016: Journal of the American Animal Hospital Association
Barb Biller, John Berg, Laura Garrett, David Ruslander, Richard Wearing, Bonnie Abbott, Mithun Patel, Diana Smith, Christine Bryan
All companion animal practices will be presented with oncology cases on a regular basis, making diagnosis and treatment of cancer an essential part of comprehensive primary care. Because each oncology case is medically unique, these guidelines recommend a patient-specific approach consisting of the following components: diagnosis, staging, therapeutic intervention, provisions for patient and personnel safety in handling chemotherapy agents, referral to an oncology specialty practice when appropriate, and a strong emphasis on client support...
July 2016: Journal of the American Animal Hospital Association
Lonneke Schuurmans, Marie-Jose Enders-Slegers, Theo Verheggen, Jos Schols
OBJECTIVES: Animal-assisted interventions (AAI) have become more and more popular in nursing homes in the past decade. Various initiatives for using animals in nursing homes have been developed over the years (eg, animal visiting programs, residential companion animals, petting zoos) and, on the whole, the number of nursing homes that refuse animals on their premises has declined. In this survey, we aimed to determine how many Dutch nursing homes offer AAIs, what type of interventions are used, and with what aim...
July 1, 2016: Journal of the American Medical Directors Association
Nao Hensel, Sonja Zabel, Patrick Hensel
BACKGROUND: The emergence of meticillin-resistant Staphylococcus pseudintermedius (MRSP) has become a significant animal health problem. Recent studies have indicated that previous antibacterial drug exposure is a factor in acquisition of meticillin-resistant strains of staphylococci. HYPOTHESIS/OBJECTIVES: The purpose of this study was to identify factors associated with prior antimicrobial drug use and MRSP pyoderma in dogs presented to a veterinary teaching hospital...
April 2016: Veterinary Dermatology
Nick Van Laeken, Olivia Taylor, Ingeborgh Polis, Sara Neyt, Ken Kersemans, Andre Dobbeleir, Jimmy Saunders, Ingeborg Goethals, Kathelijne Peremans, Filip De Vos
This first-in-dog study evaluates the use of the PET-radioligand [11C]DASB to image the density and availability of the serotonin transporter (SERT) in the canine brain. Imaging the serotonergic system could improve diagnosis and therapy of multiple canine behavioural disorders. Furthermore, as many similarities are reported between several human neuropsychiatric conditions and naturally occurring canine behavioural disorders, making this tracer available for use in dogs also provide researchers an interesting non-primate animal model to investigate human disorders...
2016: PloS One
Shreeram C Nallar, De-Qi Xu, Dhan V Kalvakolanu
Bacteria act as pro- or anti- tumorigenic agents. Whole bacteria or cytotoxic or immunogenic peptides carried by them exert potent anti-tumor effects in the experimental models of cancer. The use of attenuated microorganism(s) e.g., BCG to treat human urinary bladder cancer was found to be superior compared to standard chemotherapy. Although the phase-I clinical trials with Salmonella enterica serovar Typhimurium, has shown limited benefits in human subjects, a recent pre-clinical trial in pet dogs with tumors reported some subjects benefited from this treatment strain...
January 14, 2016: Cytokine
Federica Armas, Tommaso Furlanello, Cristina Camperio, Michele Trotta, Gianluca Novari, Cinzia Marianelli
Mycobacterium avium complex (MAC) infections have been described in many mammalian species including humans and pets. We isolated and molecularly typed the causative agent of a rare case of disseminated mycobacteriosis in a dog. We identified the pathogen as a M. avium subspecies avium by sequencing the partial genes gyrB and rpsA. Considering the zoonotic potential of this infection, and in an attempt to ensure the most effective treatment for the animal, we also determined the drug susceptibility profile of the isolate to the most common drugs used to treat MAC disease in humans...
January 12, 2016: Journal of Medical Microbiology
Meritxell Valentí Soler, Luis Agüera-Ortiz, Javier Olazarán Rodríguez, Carolina Mendoza Rebolledo, Almudena Pérez Muñoz, Irene Rodríguez Pérez, Emma Osa Ruiz, Ana Barrios Sánchez, Vanesa Herrero Cano, Laura Carrasco Chillón, Silvia Felipe Ruiz, Jorge López Alvarez, Beatriz León Salas, José M Cañas Plaza, Francisco Martín Rico, Gonzalo Abella Dago, Pablo Martínez Martín
AIMS: Pilot studies applying a humanoid robot (NAO), a pet robot (PARO) and a real animal (DOG) in therapy sessions of patients with dementia in a nursing home and a day care center. METHODS: In the nursing home, patients were assigned by living units, based on dementia severity, to one of the three parallel therapeutic arms to compare: CONTROL, PARO and NAO (Phase 1) and CONTROL, PARO, and DOG (Phase 2). In the day care center, all patients received therapy with NAO (Phase 1) and PARO (Phase 2)...
2015: Frontiers in Aging Neuroscience
Claire R Sharp, Kim A Selting, Randy Ringold
BACKGROUND: Vitamin D (vitD) deficiency is linked to many disease states including rickets and cancer, and vitD supplementation to improve response to cancer therapy has been explored. Supplementation may be most appropriate for dogs with suboptimal vitD concentrations. In dogs, the primary source of vitD is diet (predominantly via commercial dog food). Our goal was to determine how food source and supplements affect 25(OH)D concentrations, the storage form of vitD. Serum was collected from clinically healthy dogs, and pet owners were surveyed about food source and supplements...
2015: BMC Research Notes
Dita Smíšková, Olga Džupová
Pasteurella multocida is a common commensal of the gastrointestinal and respiratory tracts of animals, especially cats and dogs. It is transmitted to humans through contact with animals. Bite wound infection is the most common clinical manifestation. Systemic infections are unusual and mainly affect immunocompromised individuals. The article presents two cases of Pasteurella infection. Wound infection in a 75-year-old female following a bite from her pet cat was associated with bacteremia. The disease course was favorable with the initial clindamycin treatment despite in vitro resistance...
June 2015: Klinická Mikrobiologie a Infekc̆ní Lékar̆ství
S M Axiak-Bechtel, C A Maitz, K A Selting, J N Bryan
The development of novel radiopharmaceutical agents for imaging and therapy of neoplastic diseases relies on accurate and reproducible animal models. Rodent models are often used to demonstrate the proof-of-principle tracer and therapeutic agent development, but their small size can make tissue sampling challenging. The dosimetry of decay emissions in the much smaller rodent tumors do not model dosimetry in human tumors well. In addition, rodent models of cancer represent a simplified version of a very complex process...
September 2015: Quarterly Journal of Nuclear Medicine and Molecular Imaging
Dietmar Spelitz, N Freund, M Halabi
BACKGROUND: Infections caused by Pasteurella multocida are extremely rare in arthroplasty. We report the case of a patient who was bitten by his domestic cat, causing an infection of his knee arthroplasty. DIAGNOSIS AND TREATMENT: The puncture of the knee resulted in putrid joint effusion. After removal of the knee prosthesis, infection with Pasteurella multocida was verified. We performed a two-stage revision combined with intravenous antibiotic therapy. DISCUSSION: Infections caused by cats and dogs should attract more attention especially as prosthesis material represents a significant "locus minoris resistentiae"...
August 2015: Der Orthopäde
Alessandro Di Cerbo, Federica Pezzuto, Sergio Canello, Gianandrea Guidetti, Beniamino Palmieri
Halitosis is a common complaint involving social and communicational problems in humans and also affects the pet-owner relationship. In this randomized placebo-controlled crossover clinical evaluation, we assessed the effectiveness of a dedicated dietary supplement to improve chronic halitosis in 32 dogs of different breeds and ages. This protocol describes how to evalute the presence of oral volatile suphur compunds, e.g. methyl mercaptan, hydrogen sulfide and dimethyl sulfide, by means of a portable gas chromatograph device coupled with a syringe, which was used to collect the breath, and a dedicated software, which allows the operator to monitor each compound concentration during each measurement, in a relatively short time (8 min)...
2015: Journal of Visualized Experiments: JoVE
Yuri Ohshima-Terada, Yuki Higuchi, Takehisa Kumagai, Akihito Hagihara, Masahiko Nagata
BACKGROUND: Atopic dermatitis is a common skin disease encountered in dogs. Glucocorticoids are commonly recommended for symptomatic therapy and well-tolerated adjunctive therapies may help to reduce the necessary dose and associated risks of chronic glucocorticoid use. HYPOTHESIS/OBJECTIVES: The purpose of this study was to evaluate the complementary efficacy of oral administration of Lactobacillus paracasei K71 in canine atopic dermatitis (cAD). ANIMALS: Forty one dogs with mild to moderate cAD were recruited by19 animal hospitals...
October 2015: Veterinary Dermatology
Mariarita Romanucci, Leonardo Della Salda
Aged dogs are considered the most suitable spontaneous animal model for studying normal aging and neurodegenerative diseases. Elderly canines naturally develop cognitive dysfunction and neuropathological hallmarks similar to those seen in humans, especially Alzheimer's disease-like pathology. Pet dogs also share similar living conditions and diets to humans. Oxidative damage accumulates in the canine brain during aging, making dogs a valid model for translational antioxidant treatment/prevention studies. Evidence suggests the presence of detective protein quality control systems, involving ubiquitin-proteasome system (UPS) and Heat Shock Proteins (HSPs), in the aged canine brain...
2015: Oxidative Medicine and Cellular Longevity
Stefanie M F Seiler, Christine Baumgartner, Johannes Hirschberger, Ambros J Beer, Andreas Brühschwein, Nina Kreutzmann, Silja Laberke, Melanie C Wergin, Andrea Meyer-Lindenberg, Johanna Brandl, Anne-Kathrin von Thaden, Eliane Farrell, Markus Schwaiger
INTRODUCTION: 2-Deoxy-2-[18F]fluoro-D-glucose PET/CT is a well-established imaging method for staging, restaging and therapy-control in human medicine. In veterinary medicine, this imaging method could prove to be an attractive and innovative alternative to conventional imaging in order to improve staging and restaging. The aim of this study was both to evaluate the effectiveness of this image-guided method in canine patients with spontaneously occurring cancer as well as to illustrate the dog as a well-suited animal model for comparative oncology...
2015: PloS One
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