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https://www.readbyqxmd.com/read/29457790/cd163-macrophages-promote-angiogenesis-and-vascular-permeability-accompanied-by-inflammation-in-atherosclerosis
#1
Liang Guo, Hirokuni Akahori, Emanuel Harari, Samantha L Smith, Rohini Polavarapu, Vinit Karmali, Fumiyuki Otsuka, Rachel L Gannon, Ryan E Braumann, Megan H Dickinson, Anuj Gupta, Audrey L Jenkins, Michael J Lipinski, Johoon Kim, Peter Chhour, Paul S de Vries, Hiroyuki Jinnouchi, Robert Kutys, Hiroyoshi Mori, Matthew D Kutyna, Sho Torii, Atsushi Sakamoto, Cheol Ung Choi, Qi Cheng, Megan L Grove, Mariem A Sawan, Yin Zhang, Yihai Cao, Frank D Kolodgie, David P Cormode, Dan E Arking, Eric Boerwinkle, Alanna C Morrison, Jeanette Erdmann, Nona Sotoodehnia, Renu Virmani, Aloke V Finn
Intake of hemoglobin by the hemoglobin-haptoglobin receptor CD163 leads to a distinct alternative non-foam cell antiinflammatory macrophage phenotype that was previously considered atheroprotective. Here, we reveal an unexpected but important pathogenic role for these macrophages in atherosclerosis. Using human atherosclerotic samples, cultured cells, and a mouse model of advanced atherosclerosis, we investigated the role of intraplaque hemorrhage on macrophage function with respect to angiogenesis, vascular permeability, inflammation, and plaque progression...
February 19, 2018: Journal of Clinical Investigation
https://www.readbyqxmd.com/read/29457161/a-self-supported-amorphous-ni-p-alloy-on-a-cuo-nanowire-array-an-efficient-3d-electrode-catalyst-for-water-splitting-in-alkaline-media
#2
Bing Chang, Shuai Hao, Zhixiang Ye, Yingchun Yang
Energy-efficient electrochemical water splitting is one important way to produce hydrogen fuel but still faces many challenges. In this communication, we report that an amorphous Ni-P alloy shell electrodeposited on a CuO nanowire array supported on copper foam (CuO@Ni-P NA/CF) can be used for efficient water splitting in alkaline media. As a 3D catalytic electrode, it exhibits excellent activity both for the hydrogen evolution reaction (HER) and the oxygen evolution reaction (OER) with overpotentials of 106 mV for HER and 275 mV for OER to achieve a current density of 30 mA cm-2 in 1...
February 19, 2018: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/29455098/investigations-in-sonication-induced-intensification-of-crude-glycerol-fermentation-to-dihydroxyacetone-by-free-and-immobilized-gluconobacter-oxydans
#3
Pritam Kumar Dikshit, Gracel Joe Kharmawlong, Vijayanand S Moholkar
This study reports crude glycerol fermentation by G. oxydans for dihydroxyacetone (DHA) production, and intensification of fermentation with sonication. Fermentation was carried out using both free and immobilized cells (on polyurethane foam support) for initial glycerol concentrations of 20, 30 and 50 g/L. Sonication at 20% duty cycle enhanced glycerol consumption by 60-84% with no significant change in cell morphology. Lesser DHA yield in crude glycerol fermentation was attributed to possible formation of inhibitory products...
February 7, 2018: Bioresource Technology
https://www.readbyqxmd.com/read/29452848/optimization-of-liquid-fermentation-conditions-for-biotransformation-zein-by-cordyceps-militaris-202-and-characterization-of-physicochemical-and-functional-properties-of-fermentative-hydrolysates
#4
Shuang Yang, Mingzhu Zheng, Yong Cao, Yanjiao Dong, Sanabil, Jingsheng Liu
Cordyceps militaris 202 is a potential fungus for biotransformation zein, due to its various proteases, high tolerance and viability in nature. In this article, single factor experiment and response surface methodology were applied to optimize the liquid fermentation conditions and improve the ability of biotransformation zein. The optimized fermentation conditions were as follows: inoculum concentration of 19%, volume of liquor of 130mL/500mL and pH of 4.7. Under this condition, the degree of hydrolysis (DH) was 27...
February 13, 2018: Brazilian Journal of Microbiology: [publication of the Brazilian Society for Microbiology]
https://www.readbyqxmd.com/read/29452073/the-role-of-adiponectin-and-adipolin-as-anti-inflammatory-adipokines-in-the-formation-of-macrophage-foam-cells-and-their-association-with-cardiovascular-diseases
#5
REVIEW
Javad Sargolzaei, Elham Chamani, Tooba Kazemi, Soudabeh Fallah, Hosna Soori
Obesity is one of the major public health concerns that is closely associated with obesity-related disorders such as type 2 diabetes mellitus (T2DM), hypertension, and atherosclerosis. Atherosclerosis is a chronic disease characterized by excess cholesterol deposition in the arterial intima and the formation of foam cells. Adipocytokines or adipokines are secreted by the adipose tissue as endocrine glands; adiponectin and adipolin are among these adipokines that are associated with obese and insulin-resistant phenotypes...
February 13, 2018: Clinical Biochemistry
https://www.readbyqxmd.com/read/29448693/3d-mnco%C3%A2-o-4-5-nanorod-arrays-on-ni-foam-as-binder-free-anodes-for-li-ion-batteries
#6
Qingqing Ren, Chang Liu, Zhenbo Wang, Ke Ke, Siwen Zhang, Bosi Yin
It is a key to develop novel electrode materials with high energy and power density for advanced batteries to meet the demand of electric vehicles (EVs). Manganese cobalt oxides which can react with a large number of ions from the electrolyte for electrochemical energy storage are developing into the promising electrode materials. In this work, well-ordered MnCo2O4.5 nanorod arrays (MCO NRAs) are prepared on Ni foam by a general route of hydrothermal growth and low-temperature annealing treatment. The samples deliver a high initial capacity of 1402...
March 1, 2018: Journal of Nanoscience and Nanotechnology
https://www.readbyqxmd.com/read/29448524/effects-of-electrode-thickness-on-three-dimensional-nicral-metal-foam-cathode-for-lithium-ion-battery
#7
Kyung Yup Song, Gil Su Jang, Jin Tao, Jae Ho Lee, Seung Ki Joo
LiFePO4 electrodes using three dimensional NiCrAl alloy metal foam of different electrode thickness are prepared. In order to improve the electrochemical and cycle-life performance of lithium ion batteries, it is important to optimize the electrode thickness and mass loading of active material. As compared to those with thick electrode, the cells with thin electrode exhibit high rate performance and cycle-life behavior, due to the shorter diffusion length of lithium-ion and improved kinetic behavior. Also, cyclic voltammetry curves and electrochemical impedance spectroscopy analysis indicate that the redox reaction for the thinner electrode occurs much faster, and the charge transfer resistance is much lower...
February 1, 2018: Journal of Nanoscience and Nanotechnology
https://www.readbyqxmd.com/read/29448517/thermal-and-mechanical-characterization-of-polymeric-foams-with-controlled-porosity-using-hollow-thermoplastic-spheres
#8
Yu Bian, The Thien Ho, Younghwan Kwon, Jin Seuk Kim
Polyurethane (PU) foams with controlled porosity and pore structure are prepared via judicious study on expanding process parameters for thermoplastic expandable microspheres which are compatible with PU synthetic process. Thermal and mechanical properties of PU foams are found to be generally governed by amount of the porosity. Thermal conductivity of PU foams with controlled porosity is measured at 30 °C with transient hot bridge method. The measured thermal conductivity of PU foams is estimated using theoretical models, proving the formation of spherical pore structures of expandable microspheres in PU matrix and serving as an internal porous material...
February 1, 2018: Journal of Nanoscience and Nanotechnology
https://www.readbyqxmd.com/read/29448409/ultrasonic-measurements-of-the-bulk-flow-field-in-foams
#9
Richard Nauber, Lars Büttner, Kerstin Eckert, Jochen Fröhlich, Jürgen Czarske, Sascha Heitkam
The flow field of moving foams is relevant for basic research and for the optimization of industrial processes such as froth flotation. However, no adequate measurement technique exists for the local velocity distribution inside the foam bulk. We have investigated the ultrasound Doppler velocimetry (UDV), providing the first two-dimensional, non-invasive velocity measurement technique with an adequate spatial (10mm) and temporal resolution (2.5Hz) that is applicable to medium scale foam flows. The measurement object is dry aqueous foam flowing upward in a rectangular channel...
January 2018: Physical Review. E
https://www.readbyqxmd.com/read/29447635/sublamina-densa-type-linear-iga-bullous-dermatosis-with-iga-autoantibodies-specific-for-type-vii-collagen-a-case-report-and-clinicopathological-review-of-32-cases
#10
Natsuko Utsunomiya, Takenao Chino, Noritaka Oyama, Akira Utsunomiya, Yuka Yamaguchi, Wataru Takashima, Atsushi Tokuriki, Minoru Hasegawa
Linear IgA bullous dermatosis (LABD) is a rare autoimmune bullous disorder characterized by linear deposits of IgA at the basement membrane zone(BMZ) and/or by circulating IgA anti-BMZ antibodies. Comparing with other immuno-bullous diseases, LABD represents a heterogeneous disease entitywith diversity of pathogenic IgA autoantibodies to different hemidesmosomal antigens and an association with malignancies and occasional drug use. We herein present an 82-year-old Japanese man with LABD, whose indirect immunofluorescence using 1M NaCl-split skin showed positive staining for IgA at the dermal side alone...
November 15, 2017: Dermatology Online Journal
https://www.readbyqxmd.com/read/29446915/radially-aligned-hierarchical-nickel-nickel-iron-oxy-hydroxide-nanotubes-for-efficient-electrocatalytic-water-splitting
#11
Zhihan Wu, Zhiqiang Wang, Fengxia Geng
Designing well-controlled hierarchical structures on micrometer and nanometer scales represents one of the most important approaches for upgrading the catalytic abilities of electrocatalysts. Although NiFe (oxy)hydroxide has been widely studied as a water oxidation catalyst due to its high catalytic capability and abundance, its structural manipulation has been greatly restricted due to its inherent crystallographic stacking feature. In this work, we report for the first time the construction of a nanotube structure of NiFe (oxy)hydroxide with an inner Ni-rich layer, which was radially aligned on a macroporous nickel foam...
February 15, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29446613/hierarchical-fenip-ultrathin-carbon-nanoflakes-as-alkaline-oxygen-evolution-and-acidic-hydrogen-evolution-catalyst-for-efficient-water-electrolysis-and-organic-decomposition
#12
Bowei Zhang, Yu Hui Lui, Anand P S Gaur, Bolin Chen, Xiaohui Tang, Zhiyuan Qi, Shan Hu
Efficiency of hydrogen evolution via water electrolysis is mainly impeded by the kinetically sluggish oxygen evolution reaction (OER). Thus, it is of great significance to develop highly active and stable OER catalyst for alkaline water electrolysis or to substitute the more kinetically demanding acidic OER with a facile electron-donating reaction, such that OER is no longer the bottleneck half reaction for either acidic or alkaline water electrolysis. Herein, the hierarchical Fe-Ni phosphide shelled with ultrathin carbon networks on Ni foam (FeNiP@C) is reported and shows exceptional OER activity and enhanced chemical stability in 1M KOH...
February 15, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29446235/quantitative-evaluation-of-the-performance-of-different-deformable-image-registration-algorithms-in-helical-axial-and-cone-beam-ct-images-using-a-mobile-phantom
#13
Imad Ali, Nesreen Alsbou, Justin Jaskowiak, Salahuddin Ahmad
The goal of this project is to investigate quantitatively the performance of different deformable image registration algorithms (DIR) with helical (HCT), axial (ACT), and cone-beam CT (CBCT). The variations in the CT-number values and lengths of well-known targets moving with controlled motion were evaluated. Four DIR algorithms: Demons, Fast-Demons, Horn-Schunck and Lucas-Kanade were used to register intramodality CT images of a mobile phantom scanned with different imaging techniques. The phantom had three water-equivalent targets inserted in a low-density foam with different lengths (10-40 mm) and moved with adjustable motion amplitudes (0-20 mm) and frequencies (0-0...
February 15, 2018: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/29446015/synthetic-polymeric-biomaterials-for-wound-healing-a-review
#14
Mariam Mir, Murtaza Najabat Ali, Afifa Barakullah, Ayesha Gulzar, Munam Arshad, Shizza Fatima, Maliha Asad
Wounds are of a variety of types and each category has its own distinctive healing requirements. This realization has spurred the development of a myriad of wound dressings, each with specific characteristics. It is unrealistic to expect a singular dressing to embrace all characteristics that would fulfill generic needs for wound healing. However, each dressing may approach the ideal requirements by deviating from the 'one size fits all approach', if it conforms strictly to the specifications of the wound and the patient...
February 14, 2018: Progress in Biomaterials
https://www.readbyqxmd.com/read/29445195/ultra-high-thermal-effusivity-materials-for-resonant-ambient-thermal-energy-harvesting
#15
Anton L Cottrill, Albert Tianxiang Liu, Yuichiro Kunai, Volodymyr B Koman, Amir Kaplan, Sayalee G Mahajan, Pingwei Liu, Aubrey R Toland, Michael S Strano
Materials science has made progress in maximizing or minimizing the thermal conductivity of materials; however, the thermal effusivity-related to the product of conductivity and capacity-has received limited attention, despite its importance in the coupling of thermal energy to the environment. Herein, we design materials that maximize the thermal effusivity by impregnating copper and nickel foams with conformal, chemical-vapor-deposited graphene and octadecane as a phase change material. These materials are ideal for ambient energy harvesting in the form of what we call thermal resonators to generate persistent electrical power from thermal fluctuations over large ranges of frequencies...
February 14, 2018: Nature Communications
https://www.readbyqxmd.com/read/29444935/adenylyl-cyclase-1-as-a-major-isoform-to-generate-camp-signaling-for-apoa-1-mediated-cholesterol-efflux-pathway
#16
Wanze Tang, Weilie Ma, Hang Ding, Margarita Lin, Le Xiang, Guorong Lin, Zhizhen Zhang
HDL apolipoprotein A-1-mediated cholesterol efflux pathway requires multiple cellular proteins and signal transduction pathways, including adenylyl cyclase (AC) / cAMP signaling. Due to the existence of multiple transmembrane AC isoforms, it was not known how many AC isoforms are expressed and which ones are essential for cholesterol efflux in macrophage foam cells. These questions were investigated in THP-1 macrophages in this study. QRT-PCR detected mRNAs for all nine transmembrane AC isoforms, but only the mRNA and protein of AC1 isoform were consistently upregulated by cholesterol loading and apoA-1...
February 14, 2018: Journal of Lipid Research
https://www.readbyqxmd.com/read/29443786/improved-vacuum-sealing-drainage-for-treatment-of-surgical-site-infection-following-posterior-spinal-internal-fixation-a-case-report
#17
Hengyan Zhang, Qiyi Li
RATIONALE: Surgical site infection (SSI) following spine surgeries involving internal fixation often require removing the instrument; however, this can cause spinal instability. Previous reports have demonstrated the usefulness of vacuum sealing drainage (VSD) therapy, but the cases require wound opening, aseptic condition to replace the VSD device, and a secondary operation to close the wound. Thus, to improve the VSD treatment and develop a maneuverable procedure, make sense in spine surgery...
February 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29442981/polymer-foam-supported-chemically-reduced-graphene-oxide-conductive-networks-for-gas-sensing
#18
Jiajia Song, Yanyan Wang, Feng Zhang, Yan Ye, Yanhua Liu, Xiaohong Zhou, Linsen Chen, Changsi Peng
In this work, gas sensors based on chemically reduced graphene oxide (rGO) foams were reported for NH3 detection. Polymer foams were used as scaffolds to support rGO, and the resultant soft sensing devices exhibited a high sensitivity, high selectivity, and rapid recovery for NH3 detection at room temperature. The sensor showed more than 0.90% and 3.67% resistance changes respectively, when it's exposed to 1 ppm and 50 ppm NH3. The graphene foam gas sensors (FGS) also showed excellent repeatability. Furthermore, the response of rGO foam gas sensor to NH3 was more than two times higher than that to methanol vapors diluted to 1% of the saturated vapor concentration...
April 1, 2018: Journal of Nanoscience and Nanotechnology
https://www.readbyqxmd.com/read/29442919/synthesis-of-bimetal-fe-and-cu-altered-tud-1-a-mesoporous-catalyst-for-phenol-hydroxylation-reaction
#19
Muthusamy Poomalai Pachamuthu, Pushparaju Subhapriya
Fe and Cu ions incorporated (Si/Cu = 50, Si/Fe = 50 and Si/Cu + Fe = 50) amorphous, wormhole structured mesoporous catalysts (CuTUD-1, FeTUD-1 and FeCuTUD-1) (TUD-1-Technische Universiteit Delft) have been synthesized hydrothermally using low cost, non-surfactant template triethanolamine (TEA). Physicochemical properties of the catalysts were made using X-ray diffraction (XRD), Nitrogen sorption, FT-IR, DRS UV Visible, FT Raman, SEM, TEM and TG-DTG techniques. The results showed that the materials possess mesoporous, foam type morphology, surface area 485-634 m2/g, pore size 4...
April 1, 2018: Journal of Nanoscience and Nanotechnology
https://www.readbyqxmd.com/read/29442689/synthesis-and-characterization-of-silicon-reduced-graphene-oxide-composites-as-anodes-for-lithium-secondary-batteries
#20
Sang-Hoon Lee, Yong-Jae Kim, Ye-Seol Nam, Seong-Hyo Park, Hochun Lee, Yura Hyun, Chang-Seop Lee
Silicon (Si) is one of the most attractive anode materials for lithium secondary batteries because of its large theoretical capacity, high safety, low cost and environmental benignity. However, Si-based anode material needs to overcome the structural change of the solid-electrolyte interphase due to the large volume change during cycling. To resolve these problems of composites by exploiting the superior conductivity, large specific surface area and flexibility of graphene, we have synthesized reduced graphene oxide (rGO)/Si composite electrode via a simple dip-coating method...
July 1, 2018: Journal of Nanoscience and Nanotechnology
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