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oropharynx neoplasm

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https://www.readbyqxmd.com/read/28554574/p16-expression-in-follicular-dendritic-cell-sarcoma-a-potential-mimicker-of-hpv-related-oropharyngeal-squamous-cell-carcinoma
#1
Lingxin Zhang, Chen Yang, James S Lewis, Samir K El-Mofty, Rebecca D Chernock
Follicular dendritic cell sarcoma is a rare mesenchymal neoplasm that most commonly occurs in cervical lymph nodes. It has histologic and clinical overlap with the much more common p16-positive human papillomavirus (HPV)-related squamous cell carcinoma of the oropharynx which characteristically has nonkeratinizing morphology and often presents as an isolated neck mass. Not surprisingly, follicular dendritic cell sarcomas are commonly misdiagnosed as squamous cell carcinoma. Immunohistochemistry is helpful in separating the two entities...
May 26, 2017: Human Pathology
https://www.readbyqxmd.com/read/28530265/papillary-squamous-cell-carcinoma-of-the-palatine-tonsil-a-rare-cancer-of-the-head-and-neck
#2
A Serra, R Caltabiano, G Scalia, S Palmucci, P Di Mauro, S Cocuzza
Papillary squamous neoplasms of the upper respiratory tract are rare variants of squamous cell carcinomas. They are characterised by an exophytic, papillary growth and generally have favourable prognosis. The tumour has been described in the upper aerodigestive tract. In this context, most common sites of involvement are the larynx and hypopharynx, and rarely the oral cavity and oropharynx. The limited studies and small number of published cases of papillary squamous cell carcinoma of the palatine tonsil led us to make a complete analysis of this tumour by analysing the clinical, histological, radiological, virological and therapeutic aspects that are not always present in the literature...
May 22, 2017: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/28528690/clinical-relevance-and-implications-of-hpv-induced-neoplasia-in-different-anatomical-locations
#3
REVIEW
Elena Sophie Prigge, Magnus von Knebel Doeberitz, Miriam Reuschenbach
Human papillomaviruses (HPV) are widespread DNA viruses that can infect epithelial cells of the skin and mucosa. Most HPV infections remain clinically unapparent and clear spontaneously. In few cases, however, HPV infections persist and can cause benign and malignant neoplasms at different anatomic locations. Malignant HPV-induced neoplasms are caused by distinct types of HPV (oncogenic or high-risk (HR) HPV types) and present in the anogenital (anus, penis, uterine cervix, vagina and vulva) and head and neck (particularly oropharynx) region...
April 2017: Mutation Research
https://www.readbyqxmd.com/read/28247223/update-from-the-4th-edition-of-the-world-health-organization-classification-of-head-and-neck-tumours-hematolymphoid-tumours
#4
Noah A Brown, Kojo S J Elenitoba-Johnson
In 2017, the latest revision to the WHO Classification of Head and Neck Tumours will be released. Similar to the 2005 WHO, the codification of hematopoietic and lymphoid neoplasms of the head and neck is included within chapters pertaining to the nasal cavity and paranasal sinuses, the nasopharynx, the larynx, the oral cavity and oropharynx, the neck and the salivary glands. Herein, we describe both changes to the classification of hematolymphoid neoplasms of the head and neck since the 2005 WHO, as well as recent advances in our understanding of the underlying pathogenesis and molecular pathology of these neoplasms...
March 2017: Head and Neck Pathology
https://www.readbyqxmd.com/read/27757479/-diagnosis-and-treatment-of-parapharyngeal-space-tumors
#5
REVIEW
F Bootz, S Greschus, T van Bremen
The parapharyngeal space extends from the nasopharynx to the oropharynx. It is bordered medially by the pharyngeal wall and the constrictor pharyngis muscles, and laterally by the mandible. One distinguishes between a pre- and a poststyloid space. Tumors of the parapharyngeal space are rare and represent less than 1 % of all head and neck neoplasms. Benign (70-80 %) as well as malignant (20-30 %) tumors arise from different structures of the parapharyngeal space, mainly from salivary glands and nerve structures...
November 2016: HNO
https://www.readbyqxmd.com/read/27721622/embryonal-rhabdomyosarcoma-a-rare-oral-tumor
#6
Sila Datta, Jay Gopal Ray, Tushar Deb, Santanu Patsa
Rhabdomyosarcoma is the malignant neoplasm of striated muscle and a relatively uncommon tumor of the oral cavity. Embryonal variety is the most common subtype, observed in children below 10 years of age but occasionally seen in adolescents and young adults. The present report describes a case of embryonal rhabdomyosarcoma in the left posterior buccal mucosa, with extension in the adjacent alveolus, soft palate, oropharynx and nasopharynx of a 17-year-old female.
September 2016: Journal of Oral and Maxillofacial Pathology: JOMFP
https://www.readbyqxmd.com/read/27680099/mandibular-intraosseous-pseudocarcinomatous-hyperplasia-a-case-report
#7
Andreas Fuchs, Stefan Hartmann, Karen Ernestus, Grit Mutzbauer, Christian Linz, Roman C Brands, Alexander C Kübler, Urs D A Müller-Richter
BACKGROUND: Mandibular pseudocarcinomatous hyperplasia is a rare and generally benign pathology. We report on one of these rare cases. CASE PRESENTATION: The case history of a 73-year-old white man stated that he had a carcinoma of the oropharynx, which was primarily treated with radiotherapy and chemotherapy 4 years prior. As a result of radiotherapy he developed an osteoradionecrosis of his mandible and a consecutive pathological fracture of his left mandibular angle...
September 29, 2016: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/27133907/quality-of-life-impairment-in-patients-with-head-and-neck-cancer-and-their-caregivers-a-comparative-study
#8
COMPARATIVE STUDY
Laís Rigoni, Raphaella Falco Bruhn, Rafael De Cicco, Jossi Ledo Kanda, Leandro Luongo Matos
INTRODUCTION: Head and neck cancer represents 3% of all the types of malignant neoplasms and squamous cell carcinoma (SCC) is responsible for 90% of these cases. There have been some studies evaluating the quality of life of these patients, but little is known about the physical and emotional effects on their caregivers. OBJECTIVE: To evaluate the quality of life of patients with head and neck cancer and their caregivers by applying validated questionnaires. METHODS: Thirty patients with advanced tumors (SCC stage III or IV) and their 30 caregivers were included...
November 2016: Brazilian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/27107397/reliability-of-office-based-narrow-band-imaging-guided-flexible-laryngoscopic-tissue-samplings
#9
Catherine Chang, Wan-Ni Lin, Li-Jen Hsin, Li-Ang Lee, Chien-Yu Lin, Hsueh-Yu Li, Chun-Ta Liao, Tuan-Jen Fang
OBJECTIVES/HYPOTHESIS: Direct suspension laryngoscopic biopsy performed under general anesthesia is the conventional management for obtaining pathological diagnosis for neoplasms of the larynx, oropharynx, and hypopharynx. Since the development of distal chip laryngoscopy and digital imaging systems, transnasal flexible laryngoscopy tissue sampling has gained popularity as an office-based procedure. Additional assessment with narrow-band imaging (NBI) can help to increase the diagnostic yield...
December 2016: Laryngoscope
https://www.readbyqxmd.com/read/27032466/-prevalence-of-human-papillomavirus-infection-in-squamous-cell-carcinoma-of-the-oral-cavity-oropharynx-and-larynx
#10
Vicente José Villagómez-Ortíz, Diana Estela Paz-Delgadillo, Iván Marino-Martínez, Luis Ángel Ceseñas-Falcón, Anabel Sandoval-de la Fuente, Alfonso Reyes-Escobedo
BACKGROUND: Cancer of the head and neck comprises a group of neoplasms that share a similar anatomical origin. Most originate from the epithelium of the aerodigestive tract and 90% correspond to squamous cell carcinoma. In the last 15 years, an increase in the incidence of squamous cell carcinoma induced by human papillomavirus (HPV) has been seen, mainly types 16 and 18, which are the most frequent found in cancers of the oral cavity and oropharynx, and types 6 and 11 in laryngeal cancer...
September 2016: Cirugia y Cirujanos
https://www.readbyqxmd.com/read/26735857/large-cell-neuroendocrine-carcinoma-of-the-head-and-neck-a-clinicopathologic-series-of-10-cases-with-an-emphasis-on-hpv-status
#11
Elizabeth D Thompson, Edward B Stelow, Stacey E Mills, William H Westra, Justin A Bishop
Large cell neuroendocrine carcinoma (LCNEC) is a high-grade neuroendocrine neoplasm first described in the lung and subsequently well documented in many other anatomic sites. It has only recently been recognized that LCNEC can also occasionally arise in the head and neck. The role of human papillomavirus (HPV), which is associated with some small cell carcinomas of the head and neck, has not been investigated for LCNEC. We sought to further characterize the histologic, immunophenotypic, and clinical features of LCNEC and also investigate the role of HPV in this newly described group of tumors...
April 2016: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/26622595/a-novel-combination-of-triple-metachronous-malignancies-of-the-kidney-oropharynx-and-prostate-a-case-report
#12
Antonio Luigi Pastore, Giovanni Palleschi, Antonio Leto, Luigi Silvestri, Natale Porta, Vincenzo Petrozza, Antonio Carbone
Synchronous or metachronous malignancies are a rare event, with an incidence rate that increases with age. The present study reports the case of a 70-year-old Caucasian male who was referred to the outpatient office of the Urology Unit, Sapienza University of Rome (Latina, Italy) due to lower urinary tract symptoms. An abdominal ultrasound investigation was performed that demonstrated the presence of a right renal mass. The patient underwent right radical nephrectomy, which resulted in the definitive diagnosis of clear cell type renal cell carcinoma...
August 2015: Oncology Letters
https://www.readbyqxmd.com/read/26351764/-management-of-lung-abscess
#13
REVIEW
A Marra, L Hillejan, D Ukena
A lung abscess is an infectious pulmonary disease characterised by the presence of a pus-filled cavity within the lung parenchyma. The content of an abscess often drains into the airways spontaneously, leading to an air-fluid level visible on chest X-rays and CT scans. Primary lung abscesses occur in patients who are prone to aspiration or in otherwise healthy individuals; secondary lung abscesses typically develop in association with a stenosing lung neoplasm or a systemic disease that compromises immune defences, such as AIDS, or after organ transplantation...
October 2015: Zentralblatt Für Chirurgie
https://www.readbyqxmd.com/read/26240770/mature-nasopharyngeal-teratoma-in-a-child
#14
Ramesh Parajuli, Suman Thapa, Sushna Maharjan
Teratomas are neoplasms derived from the germ cell with components of all the three embryonic layers. These are rare neoplasms in head and neck region which can occur in any age group but are more prevalent in children. The present case is an 11-year-old girl who was brought with history of painless and progressive swelling in the oropharynx for 3 years with the associated left sided nasal blockage and nasal discharge. CT scan was suggestive of benign nasopharyngeal mass highly suspicious for lipoma. Excision of the mass was done under general anaesthesia...
2015: Case Reports in Otolaryngology
https://www.readbyqxmd.com/read/26122203/chronic-lymphocytic-leukemia-of-the-oropharyngeal-cavity-and-paranasal-sinuses-a-case-series-and-literature-review
#15
REVIEW
Myles F Melton, Aaron N Pearlman
BACKGROUND: Chronic lymphocytic leukemia (CLL) is an indolent B-lineage neoplasm responsible for 30% of all leukemias. The median age of onset is 67 years with a male predominance of 2:1. Localized infiltration in the oropharynx and paranasal sinuses is exceptionally rare. The aims of this study were (1) to add an additional case series of CLL with involvement of the oropharynx and paranasal sinuses to the literature and (2) to determine incidence and demographic data. METHODS: Retrospective chart review from 1990 to 2014...
November 2015: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/26106000/histopathological-characteristics-of-lymphomas-in-the-upper-aerodigestive-tract-a-single-institute-study-in-japan
#16
Akiko Miyagi Maeshima, Hirokazu Taniguchi, Shinichi Makita, Hideaki Kitahara, Kenichi Miyamoto, Suguru Fukuhara, Wataru Munakata, Tatsuya Suzuki, Dai Maruyama, Yukio Kobayashi, Kensei Tobinai
We analyzed the histopathological characteristics of lymphomas biopsied from the upper aerodigestive tract between 2000 and 2014 at the National Cancer Center Hospital in Japan. Of a total of 309 consecutive cases, the following incidences were observed: mature B-cell neoplasms, 77% (n = 239); mature T- and NK-cell neoplasms, 20% (n = 63); classical Hodgkin lymphomas, 0.7% (n = 2); and lymphoblastic lymphomas, 2% (n = 5). Lymphomas were most frequently (57%) detected in the oropharynx. The majority of cases (89%) were mature B-cell neoplasms (diffuse large B-cell lymphoma, 60%; follicular lymphoma, 10%), and 10% of cases were mature T-cell neoplasms...
2015: Journal of Clinical and Experimental Hematopathology: JCEH
https://www.readbyqxmd.com/read/25969936/postsurgical-imaging-of-the-oral-cavity-and-oropharynx-what-radiologists-need-to-know
#17
REVIEW
Marcio R T Garcia, Ula L Passos, Tamara A Ezzedine, Henrique B Zuppani, Regina L E Gomes, Eloisa M S Gebrim
The oral cavity and oropharynx are common locations of neoplastic lesions; neoplasms at these sites are often treated with surgery. The goal of this surgical treatment is to achieve tumor control while preserving, whenever possible, the function of local structures. The procedure used depends largely on the location and extension of the tumor and the disease stage. Follow-up evaluation of patients is done with computed tomography (CT) and magnetic resonance (MR) imaging. The ability to interpret characteristic features at CT and MR imaging is particularly important because normal anatomic structures are altered in specific patterns according to the distinct surgical technique applied...
May 2015: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/25804344/lymphoepithelial-like-carcinomas-of-the-head-and-neck
#18
REVIEW
Bruce M Wenig
Lymphoepithelial-like carcinomas (LELC) of the head and neck represent malignant neoplasms that are histologically similar to nasopharyngeal carcinoma (NPC), nonkeratinizing undifferentiated type but arise in locations other than the nasopharynx. The most common location for LELC in the head and neck is the salivary glands, in particular the parotid gland. However, LELC may arise in other sites including the oropharynx (tonsils, base of tongue), sinonasal tract, larynx, and middle ear/temporal bone. Unlike the nonkeratinizing undifferentiated type of NPC which is etiologically linked to Epstein-Barr virus (EBV), LELCs are not uniformly associated with EBV...
January 2015: Seminars in Diagnostic Pathology
https://www.readbyqxmd.com/read/25567441/-resection-of-macrosis-benign-parapharyngeal-neoplasms-via-oral-approach
#19
Shuhua Li, Hongjin Shi, Dahai Wu
OBJECTIVE: To explore investigate the feasibility of transoral removal of macrosis benign neoplasms in parapharyngeal space. METHODS: Sixteen patients with well-defined macrosis benign parapharyngeal space tumors treated by surgery from January 2005 to December 2012 were enrolled in this study. All patients were assessed by CT scan, MRI and CT angiography before surgery. Surgery for the tumors with complete peplos, locating at medial side of carotid and accessible from the oropharynx was completed with the assistance of endoscope, bipolar electrocoagulation or radiofrequency ablation system...
October 2014: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/25501054/carcinoma-ex-pleomorphic-adenoma-of-the-palate-composed-of-invasive-micropapillary-salivary-duct-carcinoma-and-adenoid-cystic-carcinoma-components-an-unusual-case-with-immunohistochemical-approach
#20
Bruno T Sedassari, Nelise A da Silva Lascane, Priscila L Tobouti, Fernanda M Pigatti, Maria I F Franco, Suzana C O M de Sousa
Carcinoma ex pleomorphic adenoma (CXPA) is an unusual epithelial malignancy that develops from a primary or recurrent pleomorphic adenoma (PA), the most common tumor of salivary glands, and constitutes about 11.5% of all carcinomas that affect these glands. Intraoral minor salivary glands and seromucous glands of the oropharynx are uncommon locations of CXPA. On histopathological examination, the tumor comprises a wide morphological spectrum with a variable proportion between the benign and malignant components with the latter often predominating and overlapping the PA, which may cause misdiagnosis...
December 2014: Medicine (Baltimore)
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