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Nerve trauma

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https://www.readbyqxmd.com/read/28534496/definitions-of-traumatic-conus-medullaris-and-cauda-equina-syndrome-a-systematic-literature-review
#1
E Brouwers, H van de Meent, A Curt, B Starremans, A Hosman, R Bartels
STUDY DESIGN: A systematic review. OBJECTIVES: Conus medullaris syndrome (CMS) and cauda equina syndrome (CES) are well-known neurological entities. It is assumed that these syndromes are different regarding neurological and functional prognosis. However, literature concerning spinal trauma is ambiguous about the exact definition of the syndromes. METHODS: A MEDLINE, EMBASE and Cochrane literature search was performed. We included original articles in which clinical descriptions of CMS and/or CES were mentioned in patients following trauma to the thoracolumbar spine...
May 23, 2017: Spinal Cord
https://www.readbyqxmd.com/read/28534301/effects-of-acetyl-l-carnitine-in-diabetic-neuropathy-and-other-geriatric-disorders
#2
REVIEW
G Sergi, S Pizzato, F Piovesan, C Trevisan, N Veronese, E Manzato
A long history of diabetes mellitus and increasing age are associated with the onset of diabetic neuropathy, a painful and highly disabling complication with a prevalence peaking at 50% among elderly diabetic patients. Acetyl-L-carnitine (ALC) is a molecule derived from the acetylation of carnitine in the mitochondria that has an essential role in energy production. It has recently been proposed as a therapy to improve the symptoms of diabetic neuropathy. ALC is widely distributed in mammalian tissues, including the brain, blood-brain barrier, brain neurons, and astrocytes...
May 22, 2017: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/28534073/surgical-treatment-of-intraforaminal-extraforaminal-lumbar-disc-herniations-many-approaches-for-few-surgical-routes
#3
REVIEW
Giorgio Lofrese, Lorenzo Mongardi, Francesco Cultrera, Giorgio Trapella, Pasquale De Bonis
BACKGROUND: Several disc disease nomenclatures and approaches for LDH exist. The traditional midline bone-destructive procedures together with approaches requiring extreme muscular retraction are being replaced by muscle sparing, targeted, stability-preserving surgical routes. The increasing speculation on LDHs and the innovative corridors described to treat them have lead to an extensive production of papers frequently treating the same topic but adopting different terminologies and reporting contradictory results...
May 22, 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/28533131/don-t-get-off-the-track
#4
Rod Foroozan, Andrew G Lee
A 43 year-old man noted decreased vision after head trauma, with normal neuroimaging acutely. He had a left homonymous hemianopia, confirmed with hemifield visual evoked potentials, from trauma to the right optic tract. Four months after trauma an MRI of the brain showed atrophy of the right optic tract, and funduscopy revealed optic disc pallor with decreased retinal nerve fiber layer measures consistent with an optic tract syndrome.
May 19, 2017: Survey of Ophthalmology
https://www.readbyqxmd.com/read/28528478/the-diagnosis-and-management-of-a-vertebral-artery-loop-causing-cervical-radiculopathy
#5
L Wood, M Czyz, S Forster, Bronek M Boszczyk
BACKGROUND: Cervical radiculopathies are rarely caused by vertebral artery loop formation, which is estimated to be present in less than 3% of patients. It is uncertain what causes the loop formation: some propose an association with spondylotic changes or trauma, whilst others suggest hypertension and atherosclerosis may be responsible. CASE REPORT 1: A 35-year-old male patient presented with signs and symptoms of cervical radiculopathy that was not improved with anterior cervical discectomy and fusion surgery performed 2 years beforehand...
May 20, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28523090/penetrating-craniomaxillofacial-injury-caused-by-a-pneumatic-nail-gun
#6
Kevin Jae Choi, Marisa Ann Ryan, Tracy Cheng, David Powers
Craniomaxillofacial injuries can be complex, requiring a multidisciplinary approach. The primary survey is always the first step in trauma management prior to proceeding with further evaluation and treatment. A 26-year-old man presented with a penetrating nail gun injury through the oral and nasal cavities. He did not present in extremis but required elective endotracheal intubation for intraoperative assessment and treatment. Airway management was enhanced by the use of lingual nerve and inferior alveolar nerve blocks via the Vazirani-Akinosi technique to maintain spontaneous respiration while the tongue was distracted from the palate...
June 2017: Craniomaxillofacial Trauma & Reconstruction
https://www.readbyqxmd.com/read/28521343/tarlov-cyst-causing-sacral-insufficiency-fracture
#7
Ross C Puffer, Marcus J Gates, William Copeland, William E Krauss, Jeremy Fogelson
BACKGROUND AND IMPORTANCE: Tarlov cysts, also known as perineural cysts, have been described as meningeal dilations of the spinal nerve root sheath between the peri- and endoneurium at the dorsal root ganglion. Most often they are found in the sacrum involving the nerve roots. Normally asymptomatic, they have been reported to present with radiculopathy, paresthesias, and even urinary or bowel dysfunction. Sacral insufficiency has not been a well-documented presentation. CLINICAL PRESENTATION: The patient is a 38-year-old female who started to develop left low back pain and buttock pain that rapidly progressed into severe pain with some radiation down the posterior aspect of her left leg...
June 1, 2017: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/28515545/traumatic-brain-injury-and-neuropsychiatric-complications
#8
REVIEW
Saeed Ahmed, Hema Venigalla, Hema Madhuri Mekala, Sara Dar, Mudasar Hassan, Shahana Ayub
Traumatic brain injury (TBI) occurs when a blow or jolt to the head or a penetrating injury results in damage to the brain. It is the most frequent cause of hospitalization in young people with a higher prevalence in men. TBI is the leading cause of disability and mortality between the ages 1 and 45. TBI can be caused either by the direct result of trauma or due to a complication of the primary injury. The most common etiological factors for TBI are falls, road traffic accidents, violent physical assaults, and injuries associated with athletic activities...
March 2017: Indian Journal of Psychological Medicine
https://www.readbyqxmd.com/read/28508239/double-crush-syndrome-caused-by-cervical-spondylosis-and-vertebral-artery-loop
#9
Young Joon Rho, Woo Jin Choe
PURPOSE: The purpose of this article is to report a successful treatment experience in a rare case of simultaneous cervical nerve root compression by spondylotic cervical foraminal stenosis and a vertebral artery loop. METHODS: 51-year-old man presented with a 4-year history of left-sided cervical pain radiating to the left shoulder with progressive exacerbation of weakness on left shoulder girdle muscles for 7 months. The patient had no history of trauma. The patient's CT and MRI revealed impingement of the left C6 cervical nerve root by a tortuous vertebral artery loop and also by narrowed left C5-6 cervical foramen that had undergone spondylotic changes...
May 15, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28506166/pacinian-corpuscles-neuroma-an-exceptional-cause-of-pain-in-the-hand
#10
Isidro Jiménez, Alberto Marcos-García, Gustavo Muratore, José Medina
Pacinian corpuscles are rapidly adapting mechanoreceptors mainly distributed in the dermis of the fingers and palm of the hand. A neuroma of the Pacinian corpuscle is a rare and extremely painful condition with a few cases reported in the literature, most of them, associated with local or repetitive trauma. We present a 71-year-old man with history of pain and swelling on his left index without history of previous trauma initially diagnosed as tenosynovitis resistant to conservative treatment in which we observed, directly in the subcutaneous plane, spherical, gray and in clusters lesions closer to the collateral nerve which were described by the pathological study as neuroma of the Pacinian corpuscles...
June 2017: Journal of Hand Surgery Asian-Pacific Volume
https://www.readbyqxmd.com/read/28505604/nrf2-and-nf-%C3%AE%C2%BAb-modulation-by-plumbagin-attenuates-functional-behavioural-and-biochemical-deficits-in-rat-model-of-neuropathic-pain
#11
Vijay Arruri, Prashanth Komirishetty, Aparna Areti, Siva Kumar Naik Dungavath, Ashutosh Kumar
BACKGROUND: Plumbagin is known to exhibit a broad range of biological activities including anti-cancer, antimicrobial and has been widely used traditionally. Nuclear factor kappa-light-chain-enhancer of activated B-cells (NF-κB) inhibitory and Nuclear factor (erythroid derived-2) like-2 (Nrf2) modulatory activities of Plumbagin have been reported already. In nerve injury model of neuropathy in rats, the role of NF-κB upregulation and declined antioxidant defence has been well recognized...
February 27, 2017: Pharmacological Reports: PR
https://www.readbyqxmd.com/read/28499298/-cochlear-implant-state-of-the-art
#12
Thomas Lenarz
Cochlear implants are the treatment of choice for the auditory rehabilitation of patients with sensory deafness. They restore the missing function of inner hair cells by transforming the acoustic signal into electrical stimuli for activation of auditory nerve fibers. Due to the very fast technology development cochlear implants provide open-set speech understanding in the majority of patients including the use of the telephone. Children can achieve a near to normal speech and language development provided their deafness is detected early after onset and implantation is performed quickly thereafter...
April 2017: Laryngo- Rhino- Otologie
https://www.readbyqxmd.com/read/28498269/real-time-intracochlear-electrocochleography-obtained-directly-through-a-cochlear-implant
#13
Michael S Harris, William Jason Riggs, Kanthaiah Koka, Leonid M Litvak, Prashant Malhotra, Aaron C Moberly, Brendan P O'Connell, Jourdan Holder, Federico Alberto Di Lella, Carlos Mario Boccio, George B Wanna, Robert F Labadie, Oliver F Adunka
HYPOTHESIS: Utilizing the cochlear implant to record electrophysiologic responses during device placement is a feasible and efficacious technique for monitoring near real-time cochlear physiology during and following electrode insertion. BACKGROUND: Minimizing intracochlear trauma during cochlear implantation has emerged as a highly researched area to help improve patient performance. Currently, conventional cochlear implant technology allows for the recording of electrically evoked compound action potentials (eCAPs)...
May 11, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28491191/internal-carotid-artery-dissection-and-pseudoaneurysm-formation-with-resultant-ipsilateral-hypoglossal-nerve-palsy
#14
Giuseppe Cruciata, Rikesh Parikh, Meera Pradhan, Jay Shah, Eric Greif, Evan G Stein
Craniocervical artery dissection is a potentially disabling condition caused by an intimal tear allowing blood to enter and dissect the media in the cranial direction which can occur spontaneously or as a result of trauma. When the dissection extends toward the adventitia, it can form a protrusion from the weakened vessel wall called a pseudoaneurysm, which may become a nidus for distal thromboembolism or cause mass effect on adjacent structures. Accurate and prompt diagnosis is critical as timely treatment can significantly reduce the risk of complications such as stroke...
June 2017: Radiology case reports
https://www.readbyqxmd.com/read/28488619/peripheral-nerve-injuries-a-retrospective-survey-of-1124-cases
#15
João A Kouyoumdjian, Carla R Graça, Vanessa F M Ferreira
BACKGROUND: Peripheral nerve injuries (PNIs) remain an important health problem often leading to severe motor disabilities predominantly in the younger population. OBJECTIVE: To analyze our experience of clinical and electrodiagnostic evaluation (EDX) of PNIs over a 26-year period. MATERIALS AND METHODS: Between 1989 and 2014, 1124 consecutive patients with 1418 PNIs were referred for clinical as well as EDX evaluation. These PNIs involved upper and lower limbs as well as the facial nerves...
May 2017: Neurology India
https://www.readbyqxmd.com/read/28476710/therapeutic-effect-of-minimally-invasive-interventional-treatment-of-brain-hematoma
#16
Lin Weiwei, Xing Bing, Deng Yiming, Zhang Zhen, Du Yifeng
To investigate the therapeutic effect of minimally invasive interventional treatment of brain hematoma, 128 patients with brain hematoma were randomly divided into two groups, including observation group (64 cases) and control group (64 cases). The observation group was performed with minimally invasive interventional therapy and drug conservative therapy was used in the control group. Clinical curative effect, treatment of neural function defect score, and quality of life score were recorded. Total effective rate in observation group was significantly higher (p<0...
September 2016: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28475649/blocking-smad2-signalling-with-loganin-attenuates-sw10-cell-cycle-arrest-induced-by-tnf-%C3%AE
#17
Gao Chao, Xiaoning Tian, Wentao Zhang, Xuehai Ou, Fei Cong, Tao Song
The activity of Schwann cells (SWCs) is very important in trauma-induced nerve repair, and tumour necrosis factor-α (TNF-α) produced during tissue injury inhibits the viability of SWCs, which delays the repair of peripheral nerves. Loganin is an iridoid glycoside that has been shown to alleviate a variety of cytotoxic effects. In the current study, we evaluated the potential efficacy and the mechanism of action of loganin in TNF-α-induced cytotoxicity in SW10 cells. The experimental results indicated that loganin blocked TNF-α-mediated Smad2 activation, downregulated the expression of the G1 phase cell cycle inhibitor p15IN4KB, and upregulated the expression of the G1 phase cell cycle activator cyclin D1-CDK4/6, which upregulated E2F-1-dependent survivin expression and relieved TNF-α-induced apoptosis in SW10 cells...
2017: PloS One
https://www.readbyqxmd.com/read/28468199/a-rare-complication-of-infraorbital-nerve-hyperesthesia-in-surgically-repaired-orbital-fracture-patients
#18
Seong Eun Cho, Ho Seong Shin, Min Sung Tak, Sang Gue Kang, Yong Seok Lee, Hyun Sung Kim, Chul Han Kim
Injury to the peripheral sensory branches of the trigeminal nerve can follow a wide variety of craniofacial injuries. Many patients with facial fractures complain about the symptom of numbness to the distribution of injured nerve, which is indicative of hypoesthesia. Hyperesthesia involving the infraorbital nerve is rare in comparison to hypoesthesia secondary to facial trauma. The authors report on 2 patients with infraorbital nerve hyperesthesia in surgically repaired orbital fracture patients. Surgical decompression of the infraorbital nerve led to rapid resolution of hyperesthesia...
May 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28465200/management-of-painful-scar-tethered-cutaneous-nerves-of-the-upper-limb
#19
T A Laing, A Sierakowski, D Elliot
We report the results of treatment by division and proximal relocation of 44 painful, scar-tethered cutaneous nerves of the upper limb in 22 patients. In all patients, neuropathic pain had developed either following surgery or trauma, but without apparent direct nerve injury. The mean duration of pain symptoms prior to relocation was 17 (range 7-44) months. Adequate treatment involved relocation of 35 nerves at a first operation for each of the 22 patients, with six patients requiring further surgery to relocate 9 nerves...
March 30, 2017: Hand Surgery and Rehabilitation
https://www.readbyqxmd.com/read/28461619/case-6-isolated-bilateral-abducens-nerve-palsy-after-closed-head-trauma-in-an-11-year-old-boy
#20
Nkeiruka Orajiaka, Prasanna Kapavarapu, Gulafsha Chaudhary, Leonid Topper, Logeswary Rajagopalan
No abstract text is available yet for this article.
May 2017: Pediatrics in Review
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