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https://www.readbyqxmd.com/read/29454164/self-reported-inhibition-predicts-history-of-suicide-attempts-in-bipolar-disorder-and-major-depression
#1
André Ponsoni, Laura Damiani Branco, Charles Cotrena, Flávio Milman Shansis, Rodrigo Grassi-Oliveira, Rochele Paz Fonseca
BACKGROUND: Studies have reliably identified an association between suicide attempts and executive functions such as decision making (DM) and inhibitory control (IC) in patients with mood disorders. As such, the present study aimed to investigate the association between inhibition, DM, impulsivity and the history of suicide attempts in individuals with bipolar (BD) or major depressive disorder (MDD), identifying which assessment instruments may be most strongly associated with suicide in clinical samples...
February 14, 2018: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/29452191/recent-advances-of-medical-foods-in-china-the-opportunities-and-challenges-under-standardization
#2
Xusheng Li, Xinwei Jiang, Jianxia Sun, Cuijuan Zhu, Weibin Bai
Malnutrition with high incidence in hospitalized patients in China has brought a significant burden of disease. Although many clinical studies have demonstrated the importance of nutritional for patients with malnutrition, the application of medical foods in China is still restricted. For the classification, limits, production and registration of medical foods, the Chinese government newly enacted a series of regulations. In this review, comparing the policy, researches, and product variety of medical foods in China with other countries, although the current status of the development of medical foods in China is still far behind that of developed countries, some of regulations are stricter than those of many other countries or organizations...
February 13, 2018: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/29451916/awareness-and-attitude-of-the-public-toward-personalized-medicine-in-korea
#3
Iyn-Hyang Lee, Hye-Young Kang, Hae Sun Suh, Sukhyang Lee, Eun Sil Oh, Hotcherl Jeong
OBJECTIVES: As personalized medicine (PM) is expected to greatly improve health outcomes, efforts have recently been made for its clinical implementation in Korea. We aimed to evaluate public awareness and attitude regarding PM. METHODS: We performed a self-administered questionnaire survey to 703 adults, who participated in the survey on a voluntary basis. The primary outcome measures included public knowledge, attitude, and acceptance of PM. We conducted multinomial multivariate logistic analysis for outcome variables with three response categories and performed multivariate logistic regression analyses for dichotomous outcome variables...
2018: PloS One
https://www.readbyqxmd.com/read/29450254/correlates-of-cannabis-vape-pen-use-and-knowledge-among-u-s-college-students
#4
Tessa Frohe, Robert F Leeman, Julie Patock-Peckham, Anthony Ecker, Shane Kraus, Dawn W Foster
Introduction: The proliferation of electronic devices, such as vape-pens, has provided alternative means for cannabis use. Research has found cannabis-vaping (i.e., vape-pen use) is associated with lower perceived risks and higher cannabis use. Knowledge of these products may increase likelihood of subsequent use. As policies for cannabis shift, beliefs that peers and family approve of this substance use (injunctive norms) increase and there has been an increase in vape-pen use among young adults (18-35 year olds); however, correlates thereof remain unknown...
June 2018: Addictive Behaviors Reports
https://www.readbyqxmd.com/read/29450233/pharmacogenomics-guided-policy-in-opioid-use-disorder-oud-management-an-ethnically-diverse-case-based-approach
#5
Earl B Ettienne, Edwin Chapman, Mary Maneno, Adaku Ofoegbu, Bradford Wilson, Beverlyn Settles-Reaves, Melissa Clarke, Georgia Dunston, Kevin Rosenblatt
Introduction: Opioid use disorder (OUD) is characterized by a problematic pattern of opioid use leading to clinically-significant impairment or distress. Opioid agonist treatment is an integral component of OUD management, and buprenorphine is often utilized in OUD management due to strong clinical evidence for efficacy. However, interindividual genetic differences in buprenorphine metabolism may result in variable treatment response, leaving some patients undertreated and at increased risk for relapse...
December 2017: Addictive Behaviors Reports
https://www.readbyqxmd.com/read/29450218/attitudes-toward-fda-regulation-of-newly-deemed-tobacco-products
#6
Sarah D Kowitt, Adam O Goldstein, Allison M Schmidt, Marissa G Hall, Noel T Brewer
Objective: To examine how smokers perceive FDA oversight of e-cigarettes, hookah, and cigars. Methods: Current US smokers (N = 1,520) participating in a randomized clinical trial of pictorial cigarette pack warnings completed a survey that included questions about attitudes toward new FDA regulations covering newly deemed tobacco products (ie, regulation of e-cigarettes, nicotine gels or liquids used in e-cigarettes, hookah, and cigars). Results: Between 47% and 56% of current smokers viewed these new FDA regulations favorably and between 17% - 24% opposed them...
October 2017: Tobacco Regulatory Science
https://www.readbyqxmd.com/read/29449786/impact-of-the-introduction-of-an-endotracheal-tube-attachment-device-on-the-incidence-and-severity-of-oral-pressure-injuries-in-the-intensive-care-unit-a-retrospective-observational-study
#7
Jaye Hampson, Cameron Green, Joanne Stewart, Lauren Armitstead, Gemma Degan, Andrea Aubrey, Eldho Paul, Ravindranath Tiruvoipati
Background: Endotracheal tube (ETT) fasteners such as the AnchorFast™ claim to assist with the prevention of oral pressure injuries in intubated patients, however evidence to support their clinical efficacy is limited. This retrospective observational study aimed to investigate the impact of the introduction of the AnchorFast™ device on the incidence of oral pressure injuries in mechanically ventilated patients. Methods: Data was collected from patient case notes and clinical incident reports for October 2010 to June 2013 ( pre-AnchorFast) and July 2013 to March 2016 ( post-AnchorFast) ...
2018: BMC Nursing
https://www.readbyqxmd.com/read/29449760/pediatric-psychologists-career-satisfaction-2015-society-of-pediatric-psychology-workforce-survey-results
#8
Marisa E Hilliard, Cheryl Brosig, Andre A A Williams, Jessica Valenzuela, Astrida Kaugars, Paul M Robins, Peggy Christidis, Karen E Stamm, Tim Wysocki
Little is known about the career satisfaction of pediatric psychologists, who specialize in psychological research, teaching, and clinical service in the context of pediatric healthcare. As part of the larger Society of Pediatric Psychology Workforce Survey and in collaboration with the American Psychological Association Center for Workforce Studies, this study aimed to: (1) describe the career domains which pediatric psychologists perceive to be important and their satisfaction in each domain, and (2) compare satisfaction of pediatric psychologists across work settings, number of positions, appointment duration, professional roles, career stage, academic rank, and gender...
December 2017: Professional Psychology, Research and Practice
https://www.readbyqxmd.com/read/29449298/clinical-validation-of-a-public-health-policy-making-platform-for-hearing-loss-evotion-protocol-for-a-big-data-study
#9
Giorgos Dritsakis, Dimitris Kikidis, Nina Koloutsou, Louisa Murdin, Athanasios Bibas, Katherine Ploumidou, Ariane Laplante-Lévesque, Niels Henrik Pontoppidan, Doris-Eva Bamiou
INTRODUCTION: The holistic management of hearing loss (HL) requires an understanding of factors that predict hearing aid (HA) use and benefit beyond the acoustics of listening environments. Although several predictors have been identified, no study has explored the role of audiological, cognitive, behavioural and physiological data nor has any study collected real-time HA data. This study will collect 'big data', including retrospective HA logging data, prospective clinical data and real-time data via smart HAs, a mobile application and biosensors...
February 15, 2018: BMJ Open
https://www.readbyqxmd.com/read/29447462/exploring-talk-about-sexuality-and-living-gay-social-lives-among-chinese-and-south-asian-gay-and-bisexual-men-in-auckland-new-zealand
#10
Jeffery Adams, Stephen Neville
OBJECTIVE: To identify ways Chinese and South Asian gay and bisexual men living in Auckland talk about issues related to sexuality and experiences of living 'gay social lives.' Results will be available to inform health policy and practice. DESIGN: A qualitative design with individual interviews and thematic analysis was used. Semi-structured digitally recorded interviews were undertaken with 27 Chinese and 17 South Asian gay and bisexual men living in Auckland...
February 15, 2018: Ethnicity & Health
https://www.readbyqxmd.com/read/29447356/barriers-to-the-availability-and-accessibility-of-controlled-medicines-for-chronic-pain-in-africa
#11
Elmang Nchako, Scottie Bussell, Carlos Nesbeth, Chisom Odoh
Africans endure a high burden of pain and suffering from HIV/AIDS and cancer, yet receive a meager amount of the world's pain medication. This tragedy occurs needlessly, given that inexpensive, effective and easily administered interventions are available. WHO has a 'three-step analgesic ladder' framework for managing cancer pain. This widely adopted clinical practice guideline is an integral part of palliative care programs and has also been applied to non-cancer pain. However, untreated pain is a major public health problem due to the discordance between scientific evidence and public policy...
February 13, 2018: International Health
https://www.readbyqxmd.com/read/29446874/transplant-recipients-are-vulnerable-under-the-medicare-part-d-benefit
#12
Lisa M Potter, Angela Q Maldonado, Krista L Lentine, Mark A Schnitzler, Zidong Zhang, Gregory P Hess, Edward Garrity, Bertram L Kasiske, David A Axelrod
Transplant immunosuppressants are often used off-label due to insufficient randomized prospective trial data to achieve organ-specific US Food and Drug Administration (FDA) approval. Transplant recipients who rely on Medicare Part D for immunosuppressant drug coverage are vulnerable to coverage denial for off-label prescriptions, unless use is supported by Centers for Medicare & Medicaid Services (CMS)-approved compendia. An integrated data set including national transplant registry data and 3 years of dispensed pharmacy records was used to identify the prevalence of immunosuppression use that is both off-label and not supported by CMS-approved compendia...
February 15, 2018: American Journal of Transplantation
https://www.readbyqxmd.com/read/29446644/an-algorithm-for-managing-adults-who-refuse-medical-treatment-in-new-south-wales
#13
Kylie Cheng, Anne Wand, Christopher Ryan, Sascha Callaghan
OBJECTIVES: The assessment and management of a patient who refuses medical treatment requires clinical skill, and consideration of the relevant law and the patient's decision-making capacity. Psychiatrists are often asked to advise in these situations. We aimed to develop an algorithm describing the relevant legal pathways to assist clinicians, especially psychiatrists, working in New South Wales (NSW), Australia. METHODS: We reviewed the academic literature on treatment refusal, relevant legislation, judicial rulings and NSW Health policy directives and guidelines...
February 1, 2018: Australasian Psychiatry: Bulletin of Royal Australian and New Zealand College of Psychiatrists
https://www.readbyqxmd.com/read/29446447/individualized-prediction-of-seizure-relapse-and-outcomes-following-antiepileptic-drug-withdrawal-after-pediatric-epilepsy-surgery
#14
Herm J Lamberink, Kim Boshuisen, Willem M Otte, Karin Geleijns, Kees P J Braun
The objective of this study was to create a clinically useful tool for individualized prediction of seizure outcomes following antiepileptic drug withdrawal after pediatric epilepsy surgery. We used data from the European retrospective TimeToStop study, which included 766 children from 15 centers, to perform a proportional hazard regression analysis. The 2 outcome measures were seizure recurrence and seizure freedom in the last year of follow-up. Prognostic factors were identified through systematic review of the literature...
February 15, 2018: Epilepsia
https://www.readbyqxmd.com/read/29444788/assessment-of-the-societal-and-individual-preferences-for-fertility-treatment-in-australia-study-protocol-for-stated-preference-discrete-choice-experiments
#15
Willings Botha, Natasha Donnolley, Marian Shanahan, Georgina M Chambers
INTRODUCTION: In Australia, societal and individual preferences for funding fertility treatment remain largely unknown. This has resulted in a lack of evidence about willingness to pay (WTP) for fertility treatment by either the general population (the funders) or infertile individuals (who directly benefit). Using a stated preference discrete choice experiment (SPDCE) approach has been suggested as a more appropriate method to inform economic evaluations of fertility treatment. We outline the protocol for an ongoing study which aims to assess fertility treatment preferences of both the general population and infertile individuals, and indirectly estimate their WTP for fertility treatment...
February 14, 2018: BMJ Open
https://www.readbyqxmd.com/read/29444774/comparison-between-different-strategies-of-rheumatic-heart-disease-echocardiographic-screening-in-brazil-data-from-the-provar-rheumatic-valve-disease-screening-program-study
#16
Bruno R Nascimento, Craig Sable, Maria Carmo P Nunes, Adriana C Diamantino, Kaciane K B Oliveira, Cassio M Oliveira, Zilda Maria A Meira, Sandra Regina T Castilho, Júlia P A Santos, Letícia Maria M Rabelo, Karlla C A Lauriano, Gabriel A L Carmo, Allison Tompsett, Antonio Luiz P Ribeiro, Andrea Z Beaton
BACKGROUND: Considering the limited accuracy of clinical examination for early diagnosis of rheumatic heart disease (RHD), echocardiography has emerged as an important epidemiological tool. The ideal setting for screening is yet to be defined. We aimed to evaluate the prevalence and pattern of latent RHD in schoolchildren (aged 5-18 years) and to compare effectiveness of screening between public schools, private schools, and primary care centers in Minas Gerais, Brazil. METHODS AND RESULTS: The PROVAR (Rheumatic Valve Disease Screening Program) study uses nonexperts and portable and handheld devices for RHD echocardiographic screening, with remote interpretation by telemedicine, according to the 2012 World Heart Federation criteria...
February 14, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29444767/patient-reported-measures-for-person-centered-coordinated-care-a-comparative-domain-map-and-web-based-compendium-for-supporting-policy-development-and-implementation
#17
Helen Lloyd, Hannah Wheat, Jane Horrell, Thavapriya Sugavanam, Benjamin Fosh, Jose M Valderas, James Close
BACKGROUND: Patient-reported measure (PRM) questionnaires were originally used in research to measure outcomes of intervention studies. They have now evolved into a diverse family of tools measuring a range of constructs including quality of life and experiences of care. Current health and social care policy increasingly advocates their use for embedding the patient voice into service redesign through new models of care such as person-centered coordinated care (P3C). If chosen carefully and used efficiently, these tools can help improve care delivery through a variety of novel ways, including system-level feedback for health care management and commissioning...
February 14, 2018: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/29444700/pharmacotherapies-for-fatigue-in-chronic-liver-disease-cld-a-systematic-review-and-meta-analysis-protocol
#18
Andem Effiong, Prerna Kumari
BACKGROUND: This is the protocol for a systematic review (and meta-analysis) of an intervention. The primary objective of this systematic review will be to assess the benefits and harms of pharmacological therapies (pharmacotherapies) for the management of fatigue in adults with CLD of any etiology. The effects of pharmacological therapies on fatigue in CLD will be compared against those of placebo, no intervention, or non-pharmacological interventions. Specifically, this review will examine whether pharmacological therapies improve CLD-associated fatigue, and if they do, what key elements are associated with their effectiveness...
February 14, 2018: Systematic Reviews
https://www.readbyqxmd.com/read/29444670/breast-cancer-in-ethiopia-evidence-for-geographic-difference-in-the-distribution-of-molecular-subtypes-in-africa
#19
Endale Hadgu, Daniel Seifu, Wondemagegnhu Tigneh, Yonas Bokretsion, Abebe Bekele, Markos Abebe, Thomas Sollie, Sofia D Merajver, Christina Karlsson, Mats G Karlsson
BACKGROUND: Breast cancer is a heterogeneous disease with several morphological and molecular subtypes. Widely accepted molecular classification system uses assessment of estrogen receptor (ER), progesterone receptor (PR), human epidermal growth factor receptor 2 (HER2) and proliferation marker Ki67. Few studies have been conducted on the incidence and molecular types of breast cancer in Sub-Saharan Africa. Previous studies mainly from Western and Central Africa, showed breast cancer to occur at younger ages and to present with aggressive features, such as high-grade, advanced stage and triple-negative phenotype (negative for ER, PR and HER2)...
February 14, 2018: BMC Women's Health
https://www.readbyqxmd.com/read/29444455/anatomists-perceptions-of-the-skills-and-attributes-required-of-newly-recruited-medical-students
#20
Bernard J Moxham, Odile Plaisant, Baptiste Lignier, Feisal Brahim
BACKGROUND AND PURPOSE: Admission procedures for recruiting students to medical school vary considerably across the world. Notwithstanding such variability, it is important to know what skills and attributes are required of the students by their teachers on entering medical school. PROCEDURES: Anatomists are often the teachers who first meet the students as they enter medical school and this report analyses, by means of a questionnaire, the putative skills required of their medical students by anatomists from the U...
February 11, 2018: Annals of Anatomy, Anatomischer Anzeiger: Official Organ of the Anatomische Gesellschaft
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