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https://www.readbyqxmd.com/read/29774859/novel-salmonella-enterica-serovar-typhimurium-genotype-levels-as-herald-of-seasonal-salmonellosis-epidemics
#1
Cristina Sotomayor, Qinning Wang, Alicia Arnott, Peter Howard, Kirsty Hope, Ruiting Lan, Vitali Sintchenko
We examined the population dynamics of Salmonella enterica serovar Typhimurium during seasonal salmonellosis epidemics in New South Wales, Australia, during 2009-2016. Of 15,626 isolates, 5%-20% consisted of novel genotypes. Seasons with salmonellosis epidemics were associated with a reduction in novel genotypes in the preceding winter and spring.
June 2018: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/29772742/characterization-of-antimicrobial-resistance-determinants-and-class-1-and-class-2-integrons-in-salmonella-enterica-spp-multidrug-resistant-isolates-from-pigs
#2
Héctor Argüello, Beatriz Guerra, Irene Rodríguez, Pedro Rubio, Ana Carvajal
Antimicrobial resistance (AMR) and Salmonella spp., are primary concerns in public health. The present study characterizes the AMR determinants of 62 multi-drug resistant (MDR) Salmonella enterica spp., isolates from swine, which were obtained between 2004⁻2006, a major source of human salmonellosis. The AMR determinants were investigated by PCR, checking the presence of class 1 and class 2 integrons and 29 resistance genes. Genes sul1 , blaTEM1 -like, aadA2 , tet (A), and dfrA12 were more prevalent ( p < 0...
May 16, 2018: Genes
https://www.readbyqxmd.com/read/29770078/evaluating-the-timeliness-of-reporting-in-a-first-nations-communicable-diseases-program
#3
A Lam, S Woods, N Ndubuka
Background: Timely reporting of communicable diseases is necessary to enable a prompt response to mitigate and control outbreaks. This is especially true among First Nations communities due to a number of factors, including unique social determinants of health, which can contribute to rapid disease transmission. Objective: To assess the timeliness of reporting for 12 notifiable communicable diseases in the Northern Inter-Tribal Health Authority, which includes 33 First Nations on-reserve communities in Northern Saskatchewan, Canada, and to assess whether there were differences in reporting times depending on degree of remoteness of community, season or year...
June 1, 2017: Canada Communicable Disease Report, Relevé des Maladies Transmissibles Au Canada
https://www.readbyqxmd.com/read/29768127/an-evaluation-of-removal-trapping-to-control-rodents-inside-homes-in-a-plague-endemic-region-of-rural-northwestern-uganda
#4
Rebecca J Eisen, Linda A Atiku, Karen A Boegler, Joseph T Mpanga, Russell E Enscore, Katherine MacMillan, Kenneth L Gage
Rodents pose a significant threat to human health, particularly in rural subsistence farming communities in Africa, where rodents threaten food security and serve as reservoirs of human pathogens, including the agents of plague, leptospirosis, murine typhus, rat-bite fever, Lassa fever, salmonellosis, and campylobacteriosis. Our study focused on the plague-endemic West Nile region of Uganda, where a majority of residents live in Uganda government-defined poverty, rely on subsistence farming for a living, and frequently experience incursions of rodents into their homes...
May 16, 2018: Vector Borne and Zoonotic Diseases
https://www.readbyqxmd.com/read/29757010/a-quantitative-risk-assessment-of-human-salmonellosis-from-consumption-of-pistachios-in-the-united-states
#5
Sofia M Santillana Farakos, Régis Pouillot, Gordon R Davidson, Rhoma Johnson, Judith Spungen, Insook Son, Nathan Anderson, Jane M VAN Doren
We developed a quantitative risk assessment model to assess the risk of human nontyphoidal salmonellosis from consumption of pistachios in the United States and to evaluate the impact of Salmonella treatments (1- to 5-log reductions). The exposure model estimating prevalence and contamination levels of Salmonella at consumption included steps in pistachio processing such as transport from grower to huller, removal of the hull through wet abrasion, separation of pistachio floaters (immature, smaller nuts) and sinkers (mature, larger nuts) in a flotation tank, drying, storage, and partitioning...
May 14, 2018: Journal of Food Protection
https://www.readbyqxmd.com/read/29755194/time-course-of-salmonella-shedding-and-antibody-response-in-naturally-infected-pigs-during-grower-finisher-stage
#6
Saranya Nair, Abdolvahab Farzan, Terry L O'Sullivan, Robert M Friendship
A longitudinal trial was conducted to determine the course of Salmonella shedding and antibody response in naturally infected grower-finisher pigs. Ten-week-old pigs ( n = 45) were transferred from a farm with history of salmonellosis and housed at a research facility. Weekly fecal samples (weeks 1 to 11) as well as tissue samples at slaughter were cultured for Salmonella. Serum samples were tested for presence of Salmonella antibody by enzyme-linked immunosorbent assay (ELISA). Data were analyzed using a multilevel mixed-effects logistic regression model...
April 2018: Canadian Journal of Veterinary Research, Revue Canadienne de Recherche Vétérinaire
https://www.readbyqxmd.com/read/29750591/salmonella-species-persistence-and-their-high-level-of-antimicrobial-resistance-in-flooded-man-made-rivers-in-china
#7
Qifa Song, Danyang Zhang, Hong Gao, Junhua Wu
Man-made rivers, owing to proximity to human habitats, facilitate transmission of salmonellosis to humans. To determine the contamination situation by Salmonella in flooded man-made rivers and thereafter the exposure risk to public health, we investigated the prevalence of Salmonella species and their antimicrobial resistance in such rivers, as well as the relationship between the incidence of local infectious diarrhea cases and the number of Salmonella isolates from patients. After a heavy flood, 95 isolates of 13 Salmonella serotypes were isolated from 80 river water samples...
May 11, 2018: Microbial Drug Resistance: MDR: Mechanisms, Epidemiology, and Disease
https://www.readbyqxmd.com/read/29747038/emerging-high-level-ciprofloxacin-resistance-and-molecular-basis-of-resistance-in-salmonella-enterica-from-humans-food-and-animals
#8
Dai Kuang, Jianmin Zhang, Xuebin Xu, Weimin Shi, Sheng Chen, Xiaowei Yang, Xudong Su, Xianming Shi, Jianghong Meng
Disease caused by nontyphoidal serotypes of Salmonella enterica is the leading cause of foodborne illness worldwide. Many serotypes have also developed resistance to antimicrobials commonly used for the treatment of salmonellosis. Here we analyze 179 ciprofloxacin-resistant isolates identified among 3680 Salmonella isolated from humans, food, animals, and water collected in Shanghai, China. They were assessed for antimicrobial susceptibility, plasmid-mediated quinolone resistance (PMQR) determinants, and mutations in quinolone resistance determination regions (QRDRs); genetic relatedness was examined using PFGE...
May 2, 2018: International Journal of Food Microbiology
https://www.readbyqxmd.com/read/29741928/comparative-study-on-antibiotic-resistance-and-dna-profiles-of-salmonella-enterica-serovar-typhimurium-isolated-from-humans-retail-foods-and-the-environment-in-shanghai-china
#9
Zengfeng Zhang, Chenyang Cao, Bin Liu, Xuebin Xu, Yanfei Yan, Shenghui Cui, Sheng Chen, Jianghong Meng, Baowei Yang
We characterized antibiotic resistance profiles, antibiotic resistance-associated genes, and pulsed-field gel electrophoresis (PFGE) patterns of 145 Salmonella enterica serotype Typhimurium isolates from human infections and retail foods that were possibly responsible for salmonellosis outbreaks from 2008 to 2012 in Shanghai, China. Resistance to at least three antibiotics was found in 66.7% of chicken isolates, 76.5% of duck isolates, 77.8% of pork isolates, and 80.5% of human isolates. Seven antibiotic resistance phenotypes were detected in chicken isolates, 16 in pork isolates, 17 in duck isolates, and 50 in human isolates...
May 9, 2018: Foodborne Pathogens and Disease
https://www.readbyqxmd.com/read/29734122/reference-1d-and-2d-electrophoresis-maps-for-potential-disease-related-proteins-in-milk-whey-from-lactating-buffaloes-and-blood-serum-from-buffalo-calves-water-buffalo-bubalus-bubalis
#10
André M Santana, Funmilola C Thomas, Daniela G Silva, Eilidh McCulloch, Ana M C Vidal, Richard J S Burchmore, José J Fagliari, Peter D Eckersall
The aim of this study was to identify potential disease related proteins in milk whey of lactating buffaloes and blood serum of buffalo calves, in order to define a reference electrophoresis map for 1-DE and 2-DE. Additionally, changes in some protein patterns from buffalo calves during salmonellosis and lactating buffaloes during mastitis are presented. Milk samples were collected and distributed into groups: Milk samples from healthy buffaloes (SCC < 100.000 cells/ml, negative microbiology and CMT) (G1, n = 5) and buffaloes with subclinical mastitis (SCC > 500...
April 26, 2018: Research in Veterinary Science
https://www.readbyqxmd.com/read/29732462/environmental-health-program-performance-and-its-relationship-with-environment-related-disease-in-florida
#11
Justin A Gerding, Nailya O DeLellis, Antonio J Neri, Timothy A Dignam
This study used a unique approach to examine Florida county health department environmental health (EH) program performance of the 10 Essential Environmental Public Health Services (EEPHS) and its relationship with environment-related disease, described by enteric disease rates. Correlation analysis tested the association between performance of each EEPHS and five different enteric disease rates, while multivariate regression analysis further examined the relationships while considering program organizational characteristics as potential confounders...
2018: Florida Public Health Review
https://www.readbyqxmd.com/read/29708083/phenotypical-resistance-correlation-networks-for-10-non-typhoidal-salmonella-subpopulations-in-an-active-antimicrobial-surveillance-programme
#12
W J Love, K A Zawack, J G Booth, Y T Gröhn, C Lanzas
Antimicrobials play a critical role in treating cases of invasive non-typhoidal salmonellosis (iNTS) and other diseases, but efficacy is hindered by resistant pathogens. Selection for phenotypical resistance may occur via several mechanisms. The current study aims to identify correlations that would allow indirect selection of increased resistance to ceftriaxone, ciprofloxacin and azithromycin to improve antimicrobial stewardship. These are medically important antibiotics for treating iNTS, but these resistances persist in non-Typhi Salmonella serotypes even though they are not licensed for use in US food animals...
April 30, 2018: Epidemiology and Infection
https://www.readbyqxmd.com/read/29703142/identification-of-new-loci-involved-in-the-host-susceptibility-to-salmonella-typhimurium-in-collaborative-cross-mice
#13
Jing Zhang, Danielle Malo, Richard Mott, Jean-Jacques Panthier, Xavier Montagutelli, Jean Jaubert
BACKGROUND: Salmonella is a Gram-negative bacterium causing a wide range of clinical syndromes ranging from typhoid fever to diarrheic disease. Non-typhoidal Salmonella (NTS) serovars infect humans and animals, causing important health burden in the world. Susceptibility to salmonellosis varies between individuals under the control of host genes, as demonstrated by the identification of over 20 genetic loci in various mouse crosses. We have investigated the host response to S. Typhimurium infection in 35 Collaborative Cross (CC) strains, a genetic population which involves wild-derived strains that had not been previously assessed...
April 27, 2018: BMC Genomics
https://www.readbyqxmd.com/read/29702318/control-of-salmonella-enterica-and-listeria-monocytogenes-in-hummus-using-allyl-isothiocyanate
#14
Amin N Olaimat, Murad A Al-Holy, Mahmoud Abu Ghoush, Anas A Al-Nabulsi, Richard A Holley
Hummus (chickpea dip) is a ready-to-eat product which has been implicated in several foodborne outbreaks and food recalls. This study aimed to screen the antimicrobial activity of allyl isothiocyanate (AITC) against 5 strains of each of Salmonella enterica and Listeria monocytogenes using a disc diffusion method. Additionally, the antimicrobial activity of 0.1-1.5% (v/w) AITC against both pathogens and aerobic bacteria in hummus was also investigated. The inhibition zones of AITC were 8.5-15 and 7.0-8.5 mm against the S...
April 21, 2018: International Journal of Food Microbiology
https://www.readbyqxmd.com/read/29701663/campylobacteriosis-salmonellosis-yersiniosis-and-listeriosis-as-zoonotic-foodborne-diseases-a-review
#15
REVIEW
Agnieszka Chlebicz, Katarzyna Śliżewska
Zoonoses are diseases transmitted from animals to humans, posing a great threat to the health and life of people all over the world. According to WHO estimations, 600 million cases of diseases caused by contaminated food were noted in 2010, including almost 350 million caused by pathogenic bacteria. Campylobacter , Salmonella , as well as Yersinia enterocolitica and Listeria monocytogenes may dwell in livestock (poultry, cattle, and swine) but are also found in wild animals, pets, fish, and rodents. Animals, often being asymptomatic carriers of pathogens, excrete them with faeces, thus delivering them to the environment...
April 26, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29700976/relationship-between-salmonella-infection-shedding-and-serology-in-fattening-pigs-in-low-moderate-prevalence-areas
#16
B San Román, V Garrido, S Sánchez, I Martínez-Ballesteros, J Garaizar, R C Mainar-Jaime, L Migura-Garcia, M J Grilló
Salmonella is a major foodborne pathogen causing important zoonosis worldwide. Pigs asymptomatically infected in mesenteric lymph nodes (MLN) can be intermittent shedders of the pathogen through faeces, being considered a major source of human infections. European baseline studies of fattening pig salmonellosis are based on Salmonella detection in MLN. This work studies the relationship between Salmonella infection in MLN and intestinal content (IC) shedding at slaughter and the relationship between the presence of the pathogen and the serologic status at farm level...
April 27, 2018: Zoonoses and Public Health
https://www.readbyqxmd.com/read/29678910/serotype-diversity-and-antimicrobial-resistance-among-salmonella-enterica-isolated-from-patients-at-an-equine-referral-hospital
#17
I M Leon, S D Lawhon, K N Norman, D S Threadgill, N Ohta, J Vinasco, H M Scott
Although Salmonella enterica can produce life-threatening colitis in horses, certain serotypes are more commonly associated with clinical disease. Our aim was to evaluate the proportional morbidity attributed to different serotypes, as well as phenotypic and genotypic antimicrobial resistance (AMR) of Salmonella isolated from patients at an equine referral hospital in the southern United States. Two-hundred-fifty-five Salmonella isolates were obtained from clinical samples of patients admitted to the hospital between 2007 and 2015...
April 20, 2018: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/29674535/draft-genome-sequences-of-20-salmonella-enterica-subsp-enterica-serovar-typhimurium-strains-isolated-from-swine-in-santa-catarina-brazil
#18
Amanda Aparecida Seribelli, Miliane Rodrigues Frazão, Júlia Cunha Gonzales, Guojie Cao, Maria Sanchez Leon, Jalusa Deon Kich, Marc William Allard, Juliana Pfrimer Falcão
Salmonellosis is a disease with a high incidence worldwide, and Salmonella enterica subsp. enterica serovar Typhimurium is one of the most clinically important serovars. We report here the draft genome sequences of 20 S. Typhimurium strains isolated from swine in Santa Catarina, Brazil. These draft genomes will improve our understanding of S. Typhimurium in Brazil.
April 19, 2018: Genome Announcements
https://www.readbyqxmd.com/read/29670862/organoid-and-enteroid-modeling-of-salmonella-infection
#19
REVIEW
Yuebang Yin, Daoguo Zhou
Salmonella are Gram-negative rod-shaped facultative anaerobic bacteria that are comprised of over 2,000 serovars. They cause gastroenteritis (salmonellosis) with headache, abdominal pain and diarrhea clinical symptoms. Salmonellosis brings a heavy burden for the public health in both developing and developed countries. Antibiotics are usually effective in treating the infected patients with severe gastroenteritis, although antibiotic resistance is on the rise. Understanding the molecular mechanisms of Salmonella infection is vital to combat the disease...
2018: Frontiers in Cellular and Infection Microbiology
https://www.readbyqxmd.com/read/29669332/paritaprevir-ritonavir-ombitasvir-plus-dasabuvir-regimen-in-the-treatment-of-genotype-1-chronic-hepatitis-c-infection-in-patients-with-severe-renal-impairment-and-end-stage-renal-disease-a-real-life-cohort
#20
Jan Sperl, Miluse Kreidlova, Dusan Merta, Klara Chmelova, Renata Senkerikova, Sona Frankova
BACKGROUND/AIMS: Chronic hepatitis C (HCV) virus infection reactivates under immunosuppressive drugs and therefore has a negative impact on long-term survival of kidney transplant recipients. Treatment-induced clearance of hepatitis C virus (HCV) in kidney transplant candidates prevents virus reactivation after transplantation. Paritaprevir/Ritonavir/Ombitasvir with Dasabuvir (PrOD) represents a highly effective treatment regimen for HCV genotype 1 (GT1), also suitable for patients with end-stage renal disease (ESRD)...
April 13, 2018: Kidney & Blood Pressure Research
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