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https://www.readbyqxmd.com/read/28931780/association-between-severity-of-obstructive-sleep-apnea-and-glycated-hemoglobin-level-in-japanese-individuals-with-and-without-diabetes
#1
Hideaki Kurosawa, Yoshifumi Saisho, Koichi Fukunaga, Mizuha Haraguchi, Wakako Yamasawa, Isao Kurihara, Tomoko Betsuyaku, Hiroshi Itoh
Aim of this study was to examine the association between the severity of obstructive sleep apnea (OSA) and dysglycemia in Japanese individuals with and without type 2 diabetes (T2DM). We enrolled 115 individuals diagnosed with OSA with an apnea hypopnea-index (AHI) ≥ 20 in whom continuous positive airway pressure (CPAP) therapy was introduced (N = 115, 44 with T2DM, age 62 ± 11 years, BMI 27.0 ± 4.4 kg/m(2) and AHI median 36.1; interquartile range 27.2-48.1). During admission, the severity of OSA was evaluated by polysomnography, and its association with glycated hemoglobin (HbA1c) level was examined...
September 20, 2017: Endocrine Journal
https://www.readbyqxmd.com/read/28927491/effectiveness-of-intranasal-sodium-hyaluronate-in-mitigating-adverse-effects-of-nasal-continuous-positive-airway-pressure-therapy
#2
(no author information available yet)
BACKGROUND: Nasal continuous positive airway pressure (CPAP) in moderate-to-severe cases of obstructive sleep apnea cancause nasal discomfort and other undesirable problems. OBJECTIVE: The aim of our study was to test the effects of sodium hyaluronate on nasal problems that patients experienced in their daily lives, sleepiness, nasal resistance to airflow, nasal mucociliary clearance, changes in inflammatory markers, and compliance to CPAP in three groups of patients with obstructive sleep apnea syndrome on CPAP therapy...
September 19, 2017: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/28923193/couples-experiences-with-continuous-positive-airway-pressure-treatment-a-dyadic-perspective
#3
Lichuan Ye, Mary T Antonelli, Danny G Willis, Karen Kayser, Atul Malhotra, Sanjay R Patel
OBJECTIVE: The majority of adults sleep with a partner, making sleep a dyadic experience. However, interventions to improve sleep have primarily focused on individuals. This qualitative analysis used a dyadic approach to identify facilitators and barriers to successful treatment of one of the most common sleep disorders, obstructive sleep apnea, with continuous positive airway pressure (CPAP). METHODS: Twenty joint qualitative interviews were conducted with couples, one couple at a time, with a sample of 20 patients with obstructive sleep apnea and their partners to develop an understanding of couples' experiences with CPAP use...
October 2017: Sleep Health
https://www.readbyqxmd.com/read/28922658/impact-of-minimally-invasive-surfactant-therapy-in-preterm-infants-at-29-32-weeks-gestation
#4
Peter A Dargaville, Sanoj K M Ali, Hamish D Jackson, Christopher Williams, Antonio G De Paoli
BACKGROUND: Most preterm infants born at 29-32 weeks gestation now avoid intubation in early life, and thus lack the usual conduit through which exogenous surfactant is given if needed. OBJECTIVE: The aim of this work was to examine whether a technique of minimally invasive surfactant therapy used selectively at 29-32 weeks gestation would improve outcomes. METHODS: We studied the impact of selective administration of surfactant (poractant alfa 100-200 mg/kg) by thin catheter in infants with respiratory distress syndrome on continuous positive airway pressure (CPAP)...
September 19, 2017: Neonatology
https://www.readbyqxmd.com/read/28921034/does-nasal-congestion-have-a-role-in-decreased-resistance-to-regular-cpap-usage
#5
Ayşe İriz, Mehmet Düzlü, Oğuz Köktürk, Yusuf Kemal Kemaloğlu, Fakih Cihat Eravcı, Mehmet Ekrem Zorlu, Recep Karamert
Nasal obstruction is known to cause resistance to continuous positive airway pressure (CPAP) therapy in obstructive sleep apnea syndrome (OSAS). In this paper, short- and long-term nasal congestion in OSAS patients receiving CPAP treatment were evaluated with acoustic rhinometry (AR). A total of 36 patients with moderate-to-severe OSAS, diagnosed with polysomnography were included in the study. Ten healthy subjects without OSAS constituted the control group. Pre-treatment nasal patency were measured with AR in all participants...
September 18, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28913484/identification-of-significant-obstructive-sleep-apnoea-in-the-obese-patient-development-of-the-novel-dx-osa-score
#6
Daniela D Godoroja, Dan Adrian Cioc
BACKGROUND AND OBJECTIVES: There is a high prevalence of undiagnosed obstructive sleep apnoea (OSA) in obese surgical patients. We investigated the extent to which anthropometric measurements can be used to identify the presence of significant OSA (Apnoea/Hypopnoea Index (AHI) ≥ 20) in adult patients. MATERIALS AND METHODS: We prospectively studied 1357 adult patients scheduled for elective laparoscopic bariatric surgery. Prior to surgery, body mass index (BMI), gender, neck circumference, STOP-Bang score, SpO2, neck and trunk fat (by dual X-ray absorptiometry) were recorded...
October 2016: Rom J Anaesth Intensive Care
https://www.readbyqxmd.com/read/28901415/effect-of-continuous-positive-airway-pressure-therapy-on-inflammatory-cytokines-and-atherosclerosis-in-patients-with-obstructive-sleep-apnea-syndrome
#7
Fa Jin, Jiannan Liu, Xiuwei Zhang, Wei Cai, Yuqiong Zhang, Wei Zhang, Jian Yang, Gan Lu, Xilong Zhang
Obstructive sleep apnea syndrome (OSAS) is known to be a risk factor for atherosclerosis (AS), derived from a series of chronic inflammatory reactions caused by hypoxia. However, the association between chronic inflammation and high blood pressure caused by hypoxia remains to be fully elucidated. The aim of the present study was to investigate the effect of continuous positive airway pressure (CPAP) therapy on inflammatory cytokines and AS. A total of 100 patients with OSAS and 50 healthy control subjects were enrolled...
August 30, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28901030/treating-osa-current-and-emerging-therapies-beyond-cpap
#8
REVIEW
Geraldo Lorenzi-Filho, Fernanda R Almeida, Patrick J Strollo
Continuous positive airway pressure (CPAP) is the standard treatment for moderate-to-severe obstructive sleep apnoea (OSA). However, adherence to CPAP is limited and non-CPAP therapies are frequently explored. Oral appliance (OA) therapy is currently widely used for the treatment of snoring, mild, moderate and severe OSA. The most commonly used and studied OA consists of a maxillary and mandibular splint which hold the lower jaw forward during sleep. The efficacy of OA is inferior to CPAP; however, the effectiveness as measured by sleepiness, quality of life, endothelial function and blood pressure is similar likely due to higher acceptance and subjective adherence...
September 12, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28899524/adherence-to-continuous-positive-airway-pressure-improves-attention-psychomotor-function-and-sleepiness-a-bias-reduction-method-with-further-assessment-of-apples
#9
Tyson H Holmes, Clete A Kushida
OBJECTIVE/BACKGROUND: Variable adherence to prescribed therapies for sleep disorders is commonplace. This study was designed to integrate three available statistical technologies (instrumental variables, residual inclusion, and shrinkage) to allow sleep investigators to employ data on variable adherence in the estimation of the causal effect of treatment as received on clinical outcomes. PATIENTS/METHODS: Using data from the Apnea Positive Pressure Long-term Efficacy Study (APPLES), regression adjustment for observed and unobserved confounders was applied to two primary neurocognitive outcomes, plus two measures of sleepiness...
September 2017: Sleep Medicine
https://www.readbyqxmd.com/read/28890204/early-caffeine-prophylaxis-and-risk-of-failure-of-initial-continuous-positive-airway-pressure-in-very-low-birth-weight-infants
#10
Ravi M Patel, Kanecia Zimmerman, David P Carlton, Reese Clark, Daniel K Benjamin, P Brian Smith
OBJECTIVE: To test the hypothesis that early caffeine treatment on the day of birth, compared with later treatment in very low birth weight (VLBW, <1500 g) infants receiving continuous positive airway pressure (CPAP) therapy, is associated with a decreased risk of CPAP failure in the first week of life. STUDY DESIGN: Multicenter, observational cohort study in 366 US neonatal intensive care units. We evaluated inborn, VLBW infants discharged from 2000 to 2014, who received only CPAP therapy without surfactant treatment on day of life (DOL) 0, had a 5-minute Apgar ≥3, and received caffeine in first week of life...
September 7, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28872099/impact-of-bariatric-surgery-on-obstructive-sleep-apnoea-hypopnea-syndrome-in-morbidly-obese-patients
#11
Pratyusha Priyadarshini, Vijay Pal Singh, Sandeep Aggarwal, Harshit Garg, Sanjeev Sinha, Randeep Guleria
BACKGROUND: Obstructive sleep apnea (OSA) is commonly associated with morbid obesity. Weight loss following bariatric surgery results in resolution or improvement of OSA. However, few studies have done objective assessment of the impact of bariatric surgery on OSA. OBJECTIVE: The aim of this study was to assess the outcome of bariatric surgery on OSA. SETTING: The study was conducted in the teaching institution of a tertiary care centre. METHODS: Twenty-seven morbidly obese patients seeking bariatric surgery were administered Epworth Sleepiness Scale (ESS) health questionnaire and subjected to overnight polysomnography...
October 2017: Journal of Minimal Access Surgery
https://www.readbyqxmd.com/read/28863162/effect-of-continuous-positive-airway-pressure-on-carotid-intima-media-thickness-in-patients-with-obstructive-sleep-apnea-a-meta-analysis
#12
Li-Da Chen, Li Lin, Xue-Jun Lin, Yang-Wu Ou, Zhi Wu, Yu-Ming Ye, Qiao-Zhen Xu, Ya-Ping Huang, Zhi-Ming Cai
OBJECTIVE: Obstructive sleep apnea (OSA) is associated with increased carotid intima-media thickness (IMT), an early marker of atherosclerosis. Continuous positive airway pressure (CPAP) is the first-line treatment for OSA. A meta-analysis was performed to determine whether CPAP therapy could decrease carotid IMT. METHODS: The PubMed, Embase, Web of Science, and Cochrane library were searched before March, 2017. Weighted mean difference (WMD) was calculated to estimate the treatment effects of pre and post-CPAP therapy...
2017: PloS One
https://www.readbyqxmd.com/read/28859723/improving-ptsd-symptoms-and-preventing-progression-of-subclinical-ptsd-to-an-overt-disorder-by-treating-comorbid-osa-with-cpap
#13
M I Ullah, Douglas G Campbell, Rajesh Bhagat, Judith A Lyons, Sadeka Tamanna
STUDY OBJECTIVES: Obstructive sleep apnea (OSA) and posttraumatic stress disorder (PTSD) are common in United States veterans. These conditions often coexist and symptoms overlap. Previous studies reported improvement in PTSD symptoms with continuous positive airway pressure (CPAP) therapy for comorbid OSA but its effect has not been assessed in a non-PTSD cohort. We have prospectively assessed the effect of CPAP therapy on clinical symptom improvement as a function of CPAP compliance levels among PTSD and non-PTSD veterans...
August 29, 2017: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/28859721/cpap-treats-enuresis-in-adults-with-obstructive-sleep-apnea
#14
Robert P McInnis, Elisabeth B Dodds, Jami Johnsen, Sanford Auerbach, Yelena Pyatkevich
Enuresis, or "bedwetting," in children is associated with obstructive sleep apnea (OSA), and often resolves with treatment of OSA. However, it is poorly understood whether a similar relationship exists in adults. We describe a case series of 5 adult patients in whom OSA was diagnosed by laboratory polysomnography, who presented with enuresis that resolved after treatment with continuous positive airway pressure (CPAP). All cases occurred in the setting of obesity, in addition to other known risk factors for urinary incontinence and enuresis...
August 29, 2017: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/28858567/effect-of-telemedicine-education-and-telemonitoring-on-cpap-adherence-the-tele-osa-randomized-trial
#15
Dennis Hwang, Jeremiah W Chang, Adam V Benjafield, Maureen E Crocker, Colleen Kelly, Kendra A Becker, Joseph B Kim, Rosa R Woodrum, Joanne Liang, Stephen F Derose
Rationale- Automated telemedicine interventions could potentially improve adherence to continuous positive airway pressure therapy (CPAP). Objective-Examining the effects of telemedicine-delivered obstructive sleep apnea (OSA) education and CPAP telemonitoring with automated patient feedback messaging on CPAP adherence. Methods-This 4-arm, randomized, factorial-design clinical trial enrolled 1455 patients (51.0% women, age 49.1±12.5 years) referred for suspected OSA. 956 underwent home sleep apnea testing and 556 were prescribed CPAP...
August 31, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/28858079/laparoscopic-vertical-sleeve-gastrectomy-a-5-year-veterans-affairs-review
#16
Rahman G Barry, Farzad A Amiri, Todd W Gress, D Blaine Nease, Timothy D Canterbury
The aim of this study was to evaluate the outcomes after laparoscopic sleeve gastrectomy (SG) in a VA population.SG has recently gained popularity as a definitive bariatric surgery procedure. Data are lacking on long-term outcomes, particularly in a Veterans Affairs population.We retrospectively reviewed 223 patients who underwent SG for morbid obesity between January 2009 and June 2014. Data on length of stay, complications, interval weight loss, comorbidities, and number of therapies preoperatively and at long-term follow-up were collected...
September 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28856971/a-comparison-of-the-effects-of-invasive-mechanic-ventilation-surfactant-therapy-and-non-invasive-nasal-continuous-positive-airway-pressure-in-preterm-newborns
#17
Muhittin Celik, Ali Bulbul, Sinan Uslu, Mesut Dursun, Omer Guran, Evrim Kıray Bas, Selda Arslan, Umut Zubarioglu
AIMS: This study compared the early-term outcomes of mechanical ventilation (MV)/surfactant treatment with nasal-continuous positive airway pressure (nCPAP) in preterm infants with respiratory distress syndrome (RDS). MATERIALS AND METHODS: Data from newborns born between ≥24 and ≤32 weeks of gestation, hospitalized at our newborn intensive care unit, and diagnosed with RDS between January 2009 and February 2012 were analyzed. RESULTS: Of 193 newborns with RDS who were enrolled in the study, 113 were treated with nCPAP and 80 with MV at a level of 57...
August 31, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28853426/obstructive-sleep-apnea-syndrome-osas-continuous-positive-airway-pressure-cpap-therapy-and-other-positive-pressure-devices
#18
Antonio Sanna
The Obstructive Sleep Apnea Syndrome (OSAS) consists of recurring episodes of complete or partial obstruction of the pharynx. The application of a continuous positive pressure in the airways (CPAP) is the first therapeutic option that is found to ensure complete patency of the pharynx during sleep, avoiding apneas and hypopneas with resolution of the symptoms. More recently, other devices have been proposed as OSAS treatment. The auto-CPAP has a role in finding the therapeutic value of the CPAP pressure rather than in OSAS therapy...
August 28, 2017: La Medicina del Lavoro
https://www.readbyqxmd.com/read/28852945/positional-therapy-in-the-management-of-positional-obstructive-sleep-apnea-a-review-of-the-current-literature
#19
REVIEW
Olabimpe Omobomi, Stuart F Quan
More than 50% of obstructive sleep apnea (OSA) patients have worsening of their OSA in the supine position (positional obstructive sleep apnea [POSA], commonly defined as supine to non-supine apnea hypopnea index (AHI) ratio of ≥ 2). Positional therapy (PT) aims to prevent patients from sleeping in the supine position. One of the major limiting factors to the routine use of PT in clinical practice is the lack of validated tools to measure compliance objectively. Furthermore, there are no universal guidelines to determine if PT will be effective as standalone or as adjunctive therapy...
August 29, 2017: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/28845957/sleep-disorders-sleep-related-breathing-disorders
#20
Deepa Burman
Sleep-related breathing disorders or sleep-disordered breathing are characterized by abnormal respiration during sleep. They are grouped into obstructive sleep apnea (OSA), central sleep apnea, sleep-related hypoventilation, and sleep-related hypoxemia disorder. OSA is a common disorder encountered in the family medicine setting that is increasingly being recognized because of the obesity epidemic and greater public and physician awareness. OSA is characterized by recurrent episodes of partial or complete closure of the upper airway resulting in disturbed breathing during sleep...
September 2017: FP Essentials
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