keyword
https://read.qxmd.com/read/38238799/cross-sectional-association-between-social-and-demographic-factors-and-disease-activity-in-rheumatoid-arthritis
#1
JOURNAL ARTICLE
Lei Zhu, Larry W Moreland, Dana Ascherman
BACKGROUND: This study aimed to assess the association between social factors, demographic parameters, and disease activity among rheumatoid arthritis (RA) patients. METHODS: The University of Pittsburgh Rheumatoid Arthritis Comparative Effectiveness Research (RACER) registry was used for this study and included patients meeting 1987 ACR criteria for RA enrolled between 2010-2015. The registry collected clinical and laboratory data at each visit, permitting the calculation of disease activity measures that included Disease Activity 28-C Reactive Protein (DAS28-CRP)...
January 19, 2024: BMC rheumatology
https://read.qxmd.com/read/37197378/is-symptom-duration-before-dmard-therapy-a-determinant-of-direct-and-indirect-costs-in-dmard-na%C3%A3-ve-ra-patients-a-systematic-review
#2
REVIEW
Ilfita Sahbudin, Ruchir Singh, Jeanette Trickey, Aliaksandra Baranskaya, Alexander Tracy, Karim Raza, Andrew Filer, Sue Jowett, Annelies Boonen
OBJECTIVE: Early treatment of RA improves clinical outcomes; however, the impact on health economic outcomes is unclear. This review sought to investigate the relationship between symptom/disease duration and resource utilization/costs and the responsiveness of costs following RA diagnosis. METHODS: A systematic search was performed on Pubmed, EMBASE, CINAHL and Medline. Studies were eligible if patients were DMARD-naïve and fulfilled 1987 ACR or 2010 ACR/EULAR RA classification criteria...
2023: Rheumatology Advances in Practice
https://read.qxmd.com/read/37095556/do-it-fast-early-access-to-specialized-care-improved-long-term-outcomes-in-rheumatoid-arthritis-data-from-the-real-multicenter-observational-study
#3
MULTICENTER STUDY
Cleandro Pires Albuquerque, Ana Paula Monteiro Gomides Reis, Ana Beatriz Vargas Santos, Manoel Barros Bértolo, Paulo Louzada Júnior, Rina Dalva Neubarth Giorgi, Sebastião Cezar Radominski, Maria Fernanda B Resende Guimarães, Karina Rossi Bonfiglioli, Maria de Fátima L Cunha Sauma, Ivânio Alves Pereira, Claiton Viegas Brenol, Licia Maria Henrique Mota, Leopoldo Santos-Neto, Geraldo Rocha Castelar Pinheiro
BACKGROUND: Early rheumatoid arthritis (RA) offers an opportunity for better treatment outcomes. In real-life settings, grasping this opportunity might depend on access to specialized care. We evaluated the effects of early versus late assessment by the rheumatologist on the diagnosis, treatment initiation and long-term outcomes of RA under real-life conditions. METHODS: Adults meeting the ACR/EULAR (2010) or ARA (1987) criteria for RA were included. Structured interviews were conducted...
April 24, 2023: Advances in Rheumatology
https://read.qxmd.com/read/36629937/incidence-of-seropositive-rheumatoid-arthritis-in-population-based-studies-in-northern-savo-finland-during-1980-2020
#4
JOURNAL ARTICLE
Pia Elfving, Aulikki Kononoff, Johanna Huhtakangas, Hannu Kautiainen, Elina Savolainen, Leena Arstila, Julia Barantseva, Tuomas Rannio, Helena Niinisalo, Antti Puolitaival, Kati Soininen, Simo Kariniemi, Minni Oksaranta, Oili Kaipiainen-Seppänen
The objective is to evaluate the incidence of seropositive rheumatoid arthritis (RA) over 40-year period in Northern Savo, Finland. Data on new seropositive RA patients according to the American College of Rheumatology (ACR) 1987 classification criteria were collected in 2020-2021. In 2020 data on tobacco exposure, patient-reported dental health and living in residences with fluoridated tap water were gathered. Incidence rates were estimated and age- and gender-adjusted to Northern Savo population. The results were compared with data acquired in studies from 1980, 1990, 2000, and 2010...
January 11, 2023: Rheumatology International
https://read.qxmd.com/read/36125425/frequency-and-pattern-of-rheumatoid-arthritis-in-a-tertiary-hospital-in-maiduguri-north-eastern-nigeria
#5
JOURNAL ARTICLE
A Yerima, U U Hassan, H U Faruk, O Adelowo
BACKGROUND: Rheumatoid arthritis (RA) is considered rare and mild in Africa, its exact burden is unknown. OBJECTIVES: To determine the pattern of RA and medications used in its management at University of Maiduguri Teaching Hospital (UMTH), Nigeria. METHODS: A retrospective cross-sectional study of RA patients, aged >18 years, satisfying the American college of rheumatology (ACR)/European alliance of associations for rheumatology (EULAR) 2010 and/or ACR 1987 classification criteria seen over six years (January 2015 to December 2020) at UMTH...
September 16, 2022: West African Journal of Medicine
https://read.qxmd.com/read/35838016/research-progress-on-serological-indices-and-their-clinical-application-in-rheumatoid-arthritis
#6
REVIEW
Shuting Meng, Longxiao Jing, Weiwei Zhang, Feng Wang, Yefeng Dong, Deping Dong
BACKGROUND: As a chronic systemic autoimmune disease of undetermined etiology, rheumatoid arthritis (RA) has a complex pathogenesis, which involves multiple proteins and cytokines. The 2010 ACR/EULAR classification criteria facilitate early diagnosis of RA with reduced specificity when compared to the 1987 ACR criteria. Hence, it is imperative to identify novel serological inflammatory indicators and targets, in order to explain the complex regulatory network of RA. The present review discusses the associations of various inflammatory factors with RA and its underlying mechanism...
September 2022: Journal of Clinical Laboratory Analysis
https://read.qxmd.com/read/34416623/assessing-improved-risk-prediction-of-rheumatoid-arthritis-by-environmental-genetic-and-metabolomic-factors
#7
JOURNAL ARTICLE
Lilia Bouzit, Susan Malspeis, Jeffrey A Sparks, Jing Cui, Elizabeth W Karlson, Kazuki Yoshida, Karen H Costenbader
OBJECTIVE: We sought to improve seropositive rheumatoid arthritis (RA) risk prediction using a novel weighted genetic risk score (wGRS) and preclinical plasma metabolites associated with RA risk. Predictive performance was compared to previously validated models including RA-associated environmental factors. METHODS: This nested case-control study matched incident seropositive RA cases (meeting ACR 1987 or EULAR/ACR 2010 criteria) in the Nurses' Health Studies (NHS) to two controls on age, blood collection features, and post-menopausal hormone use at pre-RA blood draw...
October 2021: Seminars in Arthritis and Rheumatism
https://read.qxmd.com/read/34158089/handwork-vs-machine-a-comparison-of-rheumatoid-arthritis-patient-populations-as-identified-from-ehr-free-text-by-diagnosis-extraction-through-machine-learning-or-traditional-criteria-based-chart-review
#8
JOURNAL ARTICLE
T D Maarseveen, M P Maurits, E Niemantsverdriet, A H M van der Helm-van Mil, T W J Huizinga, R Knevel
BACKGROUND: Electronic health records (EHRs) offer a wealth of observational data. Machine-learning (ML) methods are efficient at data extraction, capable of processing the information-rich free-text physician notes in EHRs. The clinical diagnosis contained therein represents physician expert opinion and is more consistently recorded than classification criteria components. OBJECTIVES: To investigate the overlap and differences between rheumatoid arthritis patients as identified either from EHR free-text through the extraction of the rheumatologist diagnosis using machine-learning (ML) or through manual chart-review applying the 1987 and 2010 RA classification criteria...
June 22, 2021: Arthritis Research & Therapy
https://read.qxmd.com/read/33928262/targeting-synovial-fibroblast-proliferation-in-rheumatoid-arthritis-trafic-an-open-label-dose-finding-phase-1b-trial
#9
JOURNAL ARTICLE
Arthur G Pratt, Stefan Siebert, Michael Cole, Deborah D Stocken, Christina Yap, Stephen Kelly, Muddassir Shaikh, Amy Cranston, Miranda Morton, Jenn Walker, Sheelagh Frame, Wan-Fai Ng, Christopher D Buckley, Iain B McInnes, Andrew Filer, John D Isaacs
BACKGROUND: Current rheumatoid arthritis therapies target immune inflammation and are subject to ceiling effects. Seliciclib is an orally available cyclin-dependent kinase inhibitor that suppresses proliferation of synovial fibroblasts-cells not yet targeted in rheumatoid arthritis. Part 1 of this phase 1b/2a trial aimed to establish the maximum tolerated dose of seliciclib in patients with active rheumatoid arthritis despite ongoing treatment with TNF inhibitors, and to evaluate safety and pharmacokinetics...
May 2021: Lancet Rheumatology
https://read.qxmd.com/read/33807932/prognostic-factors-for-radiographic-progression-in-patients-with-seronegative-rheumatoid-arthritis
#10
JOURNAL ARTICLE
Eun-Jung Park, WooSeong Jeong, Jinseok Kim
(1) Background: It has long been suggested that seronegative rheumatoid arthritis (RA) represents a clinical entity quite distinct from that of seropositive. However, analytical studies of seronegative RA dedicated to clinical outcomes regarding radiographic progression and related risk factors are scarce. The aim of this study is to evaluate radiographic outcome and prognostic factors for radiographic progression in patients with seronegative rheumatoid arthritis. (2) Methods: Subjects included RA patients reported as seronegative for both rheumatoid factor and anti-citrullinated protein antibody, who were treated at Jeju National University Hospital in South Korea between 2003 and 2016, including follow-up of at least 2 years...
March 5, 2021: Journal of Personalized Medicine
https://read.qxmd.com/read/33299019/the-prevalence-of-rheumatoid-arthritis-in-spain
#11
JOURNAL ARTICLE
Lucía Silva-Fernández, Cristina Macía-Villa, Daniel Seoane-Mato, Raúl Cortés-Verdú, Antonio Romero-Pérez, Víctor Quevedo-Vila, Dolores Fábregas-Canales, Fred Antón-Pagés, Gustavo Añez, Anahy Brandy, Cristina Martínez-Dubois, Paula Rubio-Muñoz, Carlos Sánchez-Piedra, Federico Díaz-González, Sagrario Bustabad-Reyes
Rheumatoid arthritis (RA) prevalence is believed to be around 1% worldwide, although it varies considerably among different populations. The aim of EPISER2016 study was to estimate the prevalence of RA in the general adult population in Spain. We designed a population-based cross-sectional study. A national survey was conducted between November 2016 and October 2017 involving a probabilistic sample from the general population aged 20 years or older. Subjects were randomly selected for phone screening using a computer-assisted telephone interviewer system...
December 9, 2020: Scientific Reports
https://read.qxmd.com/read/33047726/-multicenter-performance-of-the-different-classification-criteria-for-rheumatoid-arthritis
#12
MULTICENTER STUDY
C N Luo, Z F Li, L J Wu, H J Chen, C M Yang, W H Xu, X L Liu, W Tang, P Qiao, B Rena
OBJECTIVE: To evaluate the classification criteria of early rheumatoid arthritis (ERA) and compare the sensitivity and specificity with the criteria of 1987 American College of Rheumatology (ACR) criteria and 2010 ACR/European League Against Rheumatism (EULAR). METHODS: Patients from 4 hospitals, aged more than 16 years, with arthritis, whose disease duration was ≤1 year, and with ≥1 joint pain and swelling were enrolled in the study. The indicators including clinical manifestations, laboratory tests and imaging examinations were observed...
October 18, 2020: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://read.qxmd.com/read/32072351/characterizing-hand-and-wrist-ultrasound-pattern-in-primary-sj%C3%A3-gren-s-syndrome-a-case-control-study
#13
JOURNAL ARTICLE
L K N Guedes, E P Leon, T S Bocate, K R Bonfigliolli, S V Lourenço, E Bonfa, S G Pasoto
INTRODUCTION/OBJECTIVES: To evaluate the clinical relevance of high-resolution hand and wrist ultrasound (US) findings and their possible associations with anti-citrullinated peptide antibodies in primary Sjögren's syndrome (pSS). METHODS: Ninety-seven consecutive pSS patients (American-European Consensus Group, 2002) without meeting the American College of Rheumatology (ACR) criteria (1987) for rheumatoid arthritis (RA); 20 RA patients (ACR/European League Against Rheumatism (EULAR) criteria, 2010); and 80 healthy individuals with comparable age, gender, and ethnicity were enrolled in a case-control study...
June 2020: Clinical Rheumatology
https://read.qxmd.com/read/32066556/is-the-epidemiology-of-rheumatoid-arthritis-changing-results-from-a-population-based-incidence-study-1985-2014
#14
JOURNAL ARTICLE
Elena Myasoedova, John Davis, Eric L Matteson, Cynthia S Crowson
OBJECTIVES: To examine trends in the incidence of rheumatoid arthritis (RA) from 2005 to 2014 overall and by serological status as compared with 1995-2004 and 1985-1994. METHODS: We evaluated RA incidence trends in a population-based inception cohort of individuals aged <u>≥</u>18 years who first fulfilled the 1987 American College of Rheumatology (ACR) criteria for RA between 1 January 1985 and 31 December 2014. Incidence rates were estimated and were age-adjusted and sex-adjusted to the white population in the USA in 2010...
April 2020: Annals of the Rheumatic Diseases
https://read.qxmd.com/read/31834475/acpa-positive-versus-acpa-negative-rheumatoid-arthritis-two-distinct-erosive-disease-entities-on-radiography-and-ultrasonography
#15
JOURNAL ARTICLE
Julien Grosse, Edem Allado, Camille Roux, Audrey Pierreisnard, Marion Couderc, Isabelle Clerc-Urmes, Thomas Remen, Éliane Albuisson, Marcelo De Carvalho-Bittencourt, Isabelle Chary-Valckenaere, Damien Loeuille
The objective of this study is to assess the prevalence, localization, and severity of bone erosions on radiography (RX) and ultrasonography (US) according to ACPA status in patients with rheumatoid arthritis (RA). 78 patients with ACPA-positive (ACPA+) RA and 30 patients with ACPA-negative (ACPA-) RA fulfilling the ACR 1987 and/or ACR/EULAR 2010 criteria were consecutively included. On RX, a modified Sharp erosion score (SHSe) was evaluated by two blinded readers and one adjudicator for discordant cases (number of eroded joints ≤ three)...
December 13, 2019: Rheumatology International
https://read.qxmd.com/read/31829260/improved-ra-classification-among-early-arthritis-patients-with-the-concordant-presence-of-three-ra-autoantibodies-analysis-in-two-early-arthritis-clinics
#16
JOURNAL ARTICLE
Cristina Regueiro, Lorena Rodríguez-Martínez, Laura Nuño, Ana M Ortiz, Alejandro Villalba, Dora Pascual-Salcedo, Ana Martínez-Feito, Isidoro González-Alvaro, Alejandro Balsa, Antonio Gonzalez
BACKGROUND: The patients with RA benefit from early identification soon after the first clinical symptoms appear. The 2010 ACR/EULAR classification criteria were developed to fulfill this need and their application has been demonstrated to be effective. However, there is still room for improvement. Therefore, we aimed to evaluate the potential of the concordant presence of RF, anti-CCP and anti-carbamylated protein antibodies to improve current RA classification among early arthritis (EA) patients...
December 11, 2019: Arthritis Research & Therapy
https://read.qxmd.com/read/31820726/validation-of-new-classification-criteria-of-rheumatoid-arthritis-in-an-international-multicentre-study
#17
MULTICENTER STUDY
Ru Li, Xing Sun, Hua Ye, Jiajia Liu, Jinxia Zhao, Xiangyuan Liu, Yifang Mei, Zhiyi Zhang, Jialong Guo, Liqi Bi, Xia Liu, Guochun Wang, Jinjing Liu, Xiaomei Leng, Fei Gu, Lingyun Sun, Qinghua Zou, Yongfei Fang, Quan Jiang, Katerina Chatzidionysiou, Sangeetha Priya, Ramya Janardana, Aswin Nair, Anca Irinel Catrina, Debashish Danda, Zhan Guo Li
OBJECTIVES: Early identification of patients with rheumatoid arthritis (RA) is essential to allow prompt therapy. In this study, we aimed to evaluate the performance of the newly proposed ERA criteria, compared to the 1987 ACR and 2010 ACR/EULAR criteria in an international multicentre study. METHODS: A total of 606 patients with disease duration ≤2 years and age ≥16 years who were diagnosed as RA or non-RA were enrolled from China, Sweden and India...
2020: Clinical and Experimental Rheumatology
https://read.qxmd.com/read/31753003/asthma-and-elevation-of-anti-citrullinated-protein-antibodies-prior-to-the-onset-of-rheumatoid-arthritis
#18
JOURNAL ARTICLE
Alessandra Zaccardelli, Xinyi Liu, Julia A Ford, Jing Cui, Bing Lu, Su H Chu, Peter H Schur, Cameron B Speyer, Karen H Costenbader, William H Robinson, Jeremy Sokolove, Elizabeth W Karlson, Carlos A Camargo, Jeffrey A Sparks
BACKGROUND: Anti-citrullinated protein antibodies (ACPA) are central to rheumatoid arthritis (RA) pathogenesis and may develop at inflamed mucosa. We investigated whether asthma, a disease of airway mucosal inflammation, was associated with elevated ACPA before RA diagnosis. METHODS: We performed a nested case-control study among women in two prospective cohorts, the Nurses' Health Study (NHS; 1976-2014) and NHSII (1989-2015). Blood was obtained on a subset (NHS: 1989-1990; NHSII: 1996-1999)...
November 21, 2019: Arthritis Research & Therapy
https://read.qxmd.com/read/31439227/optimization-of-ultrasonographic-examination-for-the-diagnosis-of-erosive-rheumatoid-arthritis-in-comparison-to-erosive-hand-osteoarthritis
#19
COMPARATIVE STUDY
Camille Roux, Frédérique Gandjbakhch, Audrey Pierreisnard, Marion Couderc, Cédric Lukas, Racha Masri, Jean-Philippe Sommier, Isabelle Clerc-UrmeS, Cédric Baumann, Isabelle Chary-Valckenaere, Damien Loeuille
OBJECTIVE: to determine thresholds and better scenario for the diagnosis of erosive rheumatoid arthritis (RA) by ultrasonography (US) in RA in comparison to osteoarthritic (OA) patients. METHODS: Patients, prospectively included, fulfilling ACR 1987; ACR/EULAR 2010 criteria for RA or hand OA criteria. Radiographic assessment (RX): Sharp erosion score, evaluated by two blinded readers and one adjudicator for discordant cases (number of eroded joints ≤ three)...
September 2019: European Journal of Radiology
https://read.qxmd.com/read/31376995/increased-hospitalization-rates-following-heart-failure-diagnosis-in-rheumatoid-arthritis-as-compared-to-the-general-population
#20
JOURNAL ARTICLE
Elena Myasoedova, John M Davis, Eric L Matteson, Sara J Achenbach, Soko Setoguchi, Shannon M Dunlay, Veronique L Roger, Sherine E Gabriel, Cynthia S Crowson
OBJECTIVE: To compare the frequency of and trends in hospitalizations after heart failure (HF) diagnosis in patients with and without rheumatoid arthritis (RA) during 1987-2015. METHODS: The study included a retrospectively identified population-based cohort of patients with incident HF and prior RA (age≥18 years, 1987 ACR criteria) and a cohort of incident HF patients without RA matched 3:1 on age, sex, and year of HF diagnosis. Hospitalizations at the time of HF diagnosis were excluded...
July 15, 2019: Seminars in Arthritis and Rheumatism
keyword
keyword
55805
1
2
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.