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https://www.readbyqxmd.com/read/28922826/the-burnley-dog-war-the-politics-of-dog-walking-and-the-battle-over-public-parks-in-post-industrial-britain
#1
Neil Pemberton
This article investigates controversies surrounding dog walking and dog fouling in 1970s and early 1980s Britain, focusing on the microhistory of a series of events in a Lancashire mill town that became known as the 'Burnley Dog War.' A ban on dog walkers from Burnley's main public parks triggered a highly publicised seven-year struggle over access. On one level, the park ban served as a rallying cry for dog lovers across Britain, widening the dividing line between dog owners and dog haters. On another level, it constituted a struggle between antagonists over questions of belonging and exclusion in a town devastated by large-scale deindustrialisation...
June 1, 2017: 20 Century British History
https://www.readbyqxmd.com/read/28922722/molecular-mechanisms-of-anticancer-effects-of-glucosamine
#2
REVIEW
Fatemeh Zahedipour, Razieh Dalirfardouei, Gholamreza Karimi, Khadijeh Jamialahmadi
Glucosamine is an amino sugar that is produced naturally in human body. It is an essential carbohydrate component of many cellular glycoproteins, glycolipids, and glycosaminoglycans (GAGs). This popular over-the-counter supplement is also found in the exoskeleton of crustaceans. Glucosamine and its derivatives have a long history in medicine for inflammatory conditions specially to relieve arthritis. This dietary supplement has numerous biological and pharmacological properties, including anti-inflammatory, antioxidant, anti-aging, anti-fibrotic, neuroprotective and cardioprotective activities...
September 13, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28922436/genetic-risk-factors-for-autoimmune-thyroid-disease-might-affect-the-susceptibility-to-and-modulate-the-progression-of-primary-biliary-cholangitis
#3
Aleksander Kuś, Magdalena Arłukowicz-Grabowska, Konrad Szymański, Ewa Wunsch, Małgorzata Milkiewicz, Rafał Płoski, Zakera Shums, Gary L Norman, Piotr Milkiewicz, Tomasz Bednarczuk, Marcin Krawczyk
BACKGROUND AND AIMS: Patients with primary biliary cholangitis (PBC) frequently suffer from extrahepatic autoimmune conditions, of which autoimmune thyroid disease (AITD) is one of the most common. Previous studies identified several genetic variants increasing the odds of developing AITD. Here we investigate whether AITD-associated polymorphisms might also play a role in the development and clinical course of PBC and PBC associated with AITD (PBC-AITD). METHODS: To this end, we prospectively recruited 230 patients with PBC and 421 healthy controls...
September 2017: Journal of Gastrointestinal and Liver Diseases: JGLD
https://www.readbyqxmd.com/read/28922252/clinical-predictors-and-natural-history-of-disease-extension-in-patients-with-ulcerative-proctitis
#4
Emily Walsh, Young Wha Chah, Samantha M Chin, Paul Lochhead, Vijay Yajnik, Vera Denmark, John J Garber, Hamed Khalili
BACKGROUND: A proportion of patients with initial presentation of ulcerative proctitis (UP) progress to more extensive colitis. We sought to characterize the natural history and identify clinical predictors of extension in UP. METHODS: We performed a retrospective cohort study of participants with a new diagnosis of UP from January 2000 to December 2015. We used Cox proportional hazard modeling to identify predictors of disease extension. RESULTS: We identified 169 new cases of UP with a median age of diagnosis of 40 years (range: 16-91 yr) and a median follow-up of 4...
August 23, 2017: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/28921784/the-evolution-of-gonad-expenditure-and-gonadosomatic-index-gsi-in-male-and-female-broadcast-spawning-invertebrates
#5
Geoff A Parker, Steven A Ramm, Jussi Lehtonen, Jonathan M Henshaw
Sedentary broadcast-spawning marine invertebrates, which release both eggs and sperm into the water for fertilization, are of special interest for sexual selection studies. They provide unique insight into the early stages of the evolutionary succession leading to the often-intense operation of both pre- and post-mating sexual selection in mobile gonochorists. Since they are sessile or only weakly mobile, adults can interact only to a limited extent with other adults and with their own fertilized offspring...
September 18, 2017: Biological Reviews of the Cambridge Philosophical Society
https://www.readbyqxmd.com/read/28921779/local-pre-adaptation-to-disturbance-and-inbreeding-environment-interactions-affect-colonization-abilities-of-diploid-and-tetraploid-centaurea-stoebe
#6
Christoph Rosche, Isabell Hensen, Susanne Lachmuth
Primary colonization in invasive ranges most commonly occurs in disturbed habitats, where anthropogenic disturbance may cause physical damage in plants. The tolerance to such damage may differ between cytotypes and among populations as a result of differing population histories (adaptive differentiation between ruderal vs. natural habitats). Moreover, founder populations often experience inbreeding depression, the effects of which may increase through physical damage due to inbreeding-environment interactions...
September 18, 2017: Plant Biology
https://www.readbyqxmd.com/read/28921589/susceptibility-behaviour-and-retention-of-the-parasitic-salmon-louse-lepeophtheirus-salmonis-differ-with-atlantic-salmon-population-origin
#7
S Bui, S Dalvin, T Dempster, O F Skulstad, R B Edvardsen, A Wargelius, F Oppedal
Atlantic salmon populations across the world have diverse ecological and evolutionary histories, from wild anadromous or landlocked, to domestication and genetic modification. The natural host behaviours confer protection from infestation by ectoparasitic salmon lice Lepeophtheirus salmonis, yet whether genetic origin results in different behaviours and thus susceptibility to infestation is unknown. In common garden experiments, we tested antiparasite behaviours, susceptibility and retention of salmon lice in wild anadromous, wild landlocked, domesticated and genetically modified domesticated strains...
September 17, 2017: Journal of Fish Diseases
https://www.readbyqxmd.com/read/28921004/using-paleoecology-to-inform-land-management-as-climates-change-an-example-from-an-oak-savanna-ecosystem
#8
Jessica D Spencer, Andrea Brunelle, Tim Hepola
Oak savanna, a transitional ecosystem between open prairie and dense oak forest, was once widespread in Minnesota. Upon European settlement much of the oak savanna was destroyed. Recently, efforts to restore this ecosystem have increased and often include the reintroduction of fire. Though fire is known to serve an important role within oak savannas, there are currently few studies which address fire regimes on timescales longer than the last century. This research presents a paleoecological history of Sherburne National Wildlife Refuge (SNWR) in MN, USA, spanning the last ~8000 years...
September 18, 2017: Environmental Management
https://www.readbyqxmd.com/read/28919822/uterine-sarcoma-current-perspectives
#9
REVIEW
Charlotte Benson, Aisha B Miah
Uterine sarcomas comprise a group of rare tumors with differing tumor biology, natural history and response to treatment. Diagnosis is often made following surgery for presumed benign disease. Currently, preoperative imaging does not reliably distinguish between benign leiomyomas and other malignant pathology. Uterine leiomyosarcoma is the most common sarcoma, but other subtypes include endometrial stromal sarcoma (low grade and high grade), undifferentiated uterine sarcoma and adenosarcoma. Clinical trials have shown no definite survival benefit of adjuvant radiotherapy or chemotherapy and have been hampered by the rarity and heterogeneity of these disease types...
2017: International Journal of Women's Health
https://www.readbyqxmd.com/read/28919115/global-regional-and-national-under-5-mortality-adult-mortality-age-specific-mortality-and-life-expectancy-1970-2016-a-systematic-analysis-for-the-global-burden-of-disease-study-2016
#10
(no author information available yet)
BACKGROUND: Detailed assessments of mortality patterns, particularly age-specific mortality, represent a crucial input that enables health systems to target interventions to specific populations. Understanding how all-cause mortality has changed with respect to development status can identify exemplars for best practice. To accomplish this, the Global Burden of Diseases, Injuries, and Risk Factors Study 2016 (GBD 2016) estimated age-specific and sex-specific all-cause mortality between 1970 and 2016 for 195 countries and territories and at the subnational level for the five countries with a population greater than 200 million in 2016...
September 16, 2017: Lancet
https://www.readbyqxmd.com/read/28918954/contemporary-management-of-vesicoureteral-reflux
#11
REVIEW
Perviz Hajiyev, Berk Burgu
CONTEXT: Vesicoureteral reflux (VUR) remains the most interesting topic of pediatric urology due to the dynamic nature of recent controversial publications. Starting from the need for a diagnosis to the necessity and effectiveness of treatment in preventing scars, VUR remains in the mist. Although recent strong evidence helped as fog lights in this blurriness, more data are required for achieving crystal clearance. This article aims to summarize and discuss the current state of the evidence regarding VUR management...
September 11, 2017: European Urology Focus
https://www.readbyqxmd.com/read/28918949/old-growth-fishes-become-scarce-under-fishing
#12
Lewis A K Barnett, Trevor A Branch, R Anthony Ranasinghe, Timothy E Essington
Researchers have long recognized the importance of ecological differences at the species level in structuring natural communities yet until recently have often overlooked the influence of intraspecific trait variation, which can profoundly alter community dynamics [1]. Human extraction of living resources can reduce intraspecific trait variation by, for example, causing truncation of age and size structure of populations, where numbers of older individuals decline far more with exploitation than younger individuals...
September 7, 2017: Current Biology: CB
https://www.readbyqxmd.com/read/28918792/-dural-arteriovenous-fistula-is-a-rare-but-treatable-cause-of-transverse-myelitis
#13
Julie Richter Hansen, Lars Poulsgaard, Markus Holtmannspötter, Joan Højgaard, Peer Tfeldt-Hansen
This is a case report of a 60-year-old male admitted on suspicion of relapse of idiopathic transverse myelitis (TM), who after further diagnostic workup underwent successful closure of a dural arteriovenous fistula (DAVF). Magnetic resonance imaging in DAVF usually shows longitudinal TM, which, unlike DAVF, is also seen with the more common inflammatory or infectious causes usually showing inflammation in the cerebrospinal fluid. The natural history of DAVF is progressive. Since curable options exist, timely diagnosis is most important...
September 18, 2017: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/28918578/bringing-together-raptor-collections-in-europe-for-contaminant-research-and-monitoring-in-relation-to-chemicals-regulations
#14
Paola Movalli, René Dekker, Jan Koschorreck, Gabriele Treu
Raptors are good sentinels of environmental contamination and there is good capability for raptor biomonitoring in Europe. Raptor biomonitoring can benefit from natural history museums (NHMs), environmental specimen banks (ESBs) and other collections (e.g. specialist raptor specimen collections). Europe's NHMs, ESBs and other collections hold large numbers of raptor specimens and samples, covering long periods of time. These collections are potentially a valuable resource for contaminant studies over time and space...
September 16, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28917684/role-of-low-endothelial-shear-stress-and-plaque-characteristics-in-the-prediction-of-nonculprit-major-adverse-cardiac-events-the-prospect-study
#15
Peter H Stone, Akiko Maehara, Ahmet Umit Coskun, Charles C Maynard, Marina Zaromitydou, Gerasimos Siasos, Ioannis Andreou, Dimitris Fotiadis, Kostas Stefanou, Michail Papafaklis, Lampros Michalis, Alexandra J Lansky, Gary S Mintz, Patrick W Serruys, Charles L Feldman, Gregg W Stone
OBJECTIVES: This study sought to determine whether low endothelial shear stress (ESS) adds independent prognostication for future major adverse cardiac events (MACE) in coronary lesions in patients with high-risk acute coronary syndrome (ACS) from the United States and Europe. BACKGROUND: Low ESS is a proinflammatory, proatherogenic stimulus associated with coronary plaque development, progression, and destabilization in human-like animal models and in humans. Previous natural history studies including baseline ESS characterization investigated low-risk patients...
September 9, 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28917680/effusive-constrictive-pericarditis-after-pericardiocentesis-incidence-associated-findings-and-natural-history
#16
Kye Hun Kim, William R Miranda, Larry J Sinak, Faisal F Syed, Rowlens M Melduni, Raul E Espinosa, Garvan C Kane, Jae K Oh
OBJECTIVES: This study sought to investigate the incidence, associated findings, and natural history of effusive-constrictive pericarditis (ECP) after pericardiocentesis. BACKGROUND: ECP is characterized by the coexistence of tense pericardial effusion and constriction of the heart by the visceral pericardium. Echocardiography is currently the main diagnostic tool in the assessment of pericardial disease, but limited data have been published on the incidence and prognosis of ECP diagnosed by echo-Doppler...
September 9, 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28917614/age-and-fecundability-in-a-north-american-preconception-cohort-study
#17
Amelia K Wesselink, Kenneth J Rothman, Elizabeth E Hatch, Ellen M Mikkelsen, Henrik T Sørensen, Lauren A Wise
BACKGROUND: There is a well-documented decline in fertility treatment success with increasing female age; however, there are few preconception cohort studies examining female age and natural fertility. In addition, data on male age and fertility is inconsistent. Given the increasing number of couples attempting conception at older ages, a more detailed characterization of age-related fecundability in the general population is of great clinical utility. OBJECTIVE: To examine the association between female and male age with fecundability...
September 13, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28917219/reuma-pt-contribution-to-the-knowledge-of-immune-mediated-systemic-rheumatic-diseases
#18
Maria José Santos, Helena Canhão, Ana Filipa Mourão, Filipa Oliveira Ramos, Cristina Ponte, Cátia Duarte, Anabela Barcelos, Fernando Martins, José António Melo Gomes
Patient registries are key instruments aimed at a better understanding of the natural history of diseases, at assessing the effectiveness of therapeutic interventions, as well as identifying rare events or outcomes that are not captured in clinical trials. However, the potential of registries goes far beyond these aspects. For example, registries promote the standardization of clinical practice, can also provide information on domains that are not routinely collected in clinical practice and can support decision-making...
September 14, 2017: Acta Reumatológica Portuguesa
https://www.readbyqxmd.com/read/28917189/protective-factors-promoting-resilience-in-the-relation-between-child-sexual-victimization-and-internalizing-and-externalizing-symptoms
#19
Alba Pérez-González, Georgina Guilera, Noemí Pereda, Adolfo Jarne
Sexual victimization has been one of the most frequently studied forms of child victimization. Its effects are common and diverse; however, not all children and youth exposed to sexual victimization eventually develop adjustment problems. A total of 1105 children and youth (590 male and 515 female) aged between 12 and 17 from northeastern Spain were assessed regarding their experiences of sexual victimization, symptoms of psychopathology, and protective factors. The results showed that all forms of sexual victimization were associated with higher levels of emotional and behavioral problems...
September 13, 2017: Child Abuse & Neglect
https://www.readbyqxmd.com/read/28915805/antibiotic-resistance-it-s-bad-but-why-isn-t-it-worse
#20
REVIEW
Nicholas Waglechner, Gerard D Wright
Antibiotic natural products are ancient and so is resistance. Consequently, environmental bacteria harbor numerous and varied antibiotic resistance elements. Nevertheless, despite long histories of antibiotic production and exposure, environmental bacteria are not resistant to all known antibiotics. This means that there are barriers to the acquisition of a complete resistance armamentarium. The sources, distribution, and movement of resistance mechanisms in different microbes and bacterial populations are mosaic features that act as barriers to slow this movement, thus moderating the emergence of bacterial pan-resistance...
September 15, 2017: BMC Biology
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