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https://www.readbyqxmd.com/read/29664857/restrictive-versus-liberal-strategy-for-red-blood-cell-transfusion-a-systematic-review-and-meta-analysis-in-orthopaedic-patients
#1
Wan-Jie Gu, Xiao-Ping Gu, Xiang-Dong Wu, Hao Chen, Joey S W Kwong, Lu-Yang Zhou, Shuo Chen, Zheng-Liang Ma
BACKGROUND: Current guidelines recommend restrictive criteria for red blood-cell transfusion in most clinical settings. However, patients undergoing orthopaedic surgery may require distinct transfusion criteria since benefits and potential harm often vary considerably based on patient characteristics and surgical procedures. We aimed to assess the efficacy and safety of restrictive transfusion in patients undergoing orthopaedic surgery, especially in important subgroups. METHODS: Electronic databases were searched to identify randomized controlled trials investigating restrictive (mostly a hemoglobin level of 8...
April 18, 2018: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/29652077/the-implications-of-cocaine-use-and-associated-behaviors-on-adverse-cv-outcomes-among-veterans-insights-from-the-va-clinical-assessment-reporting-and-tracking-cart-program
#2
Ateka Gunja, Maggie A Stanislawski, Anna E Barón, Thomas M Maddox, Steven M Bradley, Mladen I Vidovich
BACKGROUND: Cocaine use has been associated with adverse cardiovascular outcomes in patients with coronary artery disease. It is unclear if this association is due to direct effects of cocaine or other factors. METHODS: The Veterans Affairs cardiac catheterization database was used to identify Veterans undergoing coronary catheterization between 2007 and 2014. We analyzed association between cocaine use and 1-year all-cause mortality, myocardial infarction (MI), and cerebrovascular accident (CVA) among Veterans with obstructive CAD (N=122,035)...
April 13, 2018: Clinical Cardiology
https://www.readbyqxmd.com/read/29643703/associations-of-ambient-temperature-with-mortality-rates-of-cardiovascular-and-respiratory-diseases-in-taiwan-a-subtropical-country
#3
Li-Tan Yang, Yao-Mao Chang, Tsung-Han Hsieh, Wen-Hsuan Hou, Chung-Yi Li
Background: We conducted a time-series analysis of daily ambient temperature and all-cause, cardiovascular, and respiratory disease mortality in Taiwan, which is generally neither extremely hot nor cold. Methods: Data on all-cause daily mortality rates (excluding accidents, suicide, and homicide), and mortality rates due to respiratory and cardiovascular diseases between 2008 and 2010 were obtained from the Taiwan Death Registry. The daily temperature for that period was averaged from 33 monitoring stations nationwide...
March 2018: Acta Cardiologica Sinica
https://www.readbyqxmd.com/read/29628593/comparison-of-esmolol-and-dexmedetomidine-for-suppression-of-hemodynamic-response-to-laryngoscopy-and-endotracheal-intubation-in-adult-patients-undergoing-elective-general-surgery-a-prospective-randomized-controlled-double-blinded-study
#4
Sandeep Sharma, Om Prakash Suthar, M L Tak, Abhilasha Thanvi, Naveen Paliwal, Rakesh Karnawat
Context: Laryngoscopy and endotracheal intubation lead to strong sympathetic response which may precipitate arrhythmias, myocardial ischemia and cerebrovascular accidents in patients with preexisting cardiovascular disease. Aims: This study was aimed to compare the effect of dexmedetomidine and esmolol on hemodynamic response to laryngoscopy and endotracheal intubation in patients undergoing elective surgery under general anesthesia. Settings and Design: This was a prospective, randomized controlled double-blinded study...
January 2018: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/29627585/cardiovascular-correlates-of-emotional-state-cognitive-workload-and-time-on-task-effect-during-a-realistic-flight-simulation
#5
Antonio R Hidalgo-Muñoz, Damien Mouratille, Nadine Matton, Mickaël Causse, Yves Rouillard, Radouane El-Yagoubi
In aviation, emotion and cognitive workload can considerably increase the probability of human error. An accurate online physiological monitoring of pilot's mental state could prevent accidents. The heart rate (HR) and heart rate variability (HRV) of 21 private pilots were analysed during two realistic flight simulator scenarios. Emotion was manipulated by a social stressor and cognitive workload with the difficulty of a secondary task. Our results confirmed the sensitivity of the HR to cognitive demand and training effects, with increased HR when the task was more difficult and decreased HR with training (time-on-task)...
April 5, 2018: International Journal of Psychophysiology
https://www.readbyqxmd.com/read/29590473/disability-rating-age-at-death-and-cause-of-death-in-u-s-veterans-with-service-connected-conditions
#6
Charles Maynard, Ranak Trivedi, Karin Nelson, Stephan D Fihn
Introduction: The association between disability and cause of death in Veterans with service-connected disabilities has not been studied. The objective of this study was to compare age at death, military service and disability characteristics, including disability rating, and cause of death by year of birth. We also examined cause of death for specific service-connected conditions. Materials and methods: This study used information from the VETSNET file, which is a snapshot of selected items from the Veterans Benefits Administration corporate database...
March 26, 2018: Military Medicine
https://www.readbyqxmd.com/read/29588079/risk-of-cardiovascular-disease-and-venous-thromboembolism-among-patients-with-incident-anca-associated-vasculitis-a-20-year-population-based-cohort-study
#7
Alvise Berti, Eric L Matteson, Cynthia S Crowson, Ulrich Specks, Divi Cornec
OBJECTIVE: To assess the cardiovascular disease (CVD) and venous thromboembolism (VTE) risks among patients with newly diagnosed antineutrophil cytoplasmic antibodies (ANCA)-associated vasculitis (AAV). PATIENTS AND METHODS: A population-based incident AAV cohort of 58 patients diagnosed between 1996 and 2015 in Olmsted County, MN, was identified by medical record review. For each patient, 3 age- and sex-matched non-AAV comparators were randomly selected from the same population and assigned an index date corresponding to the AAV incidence date...
March 24, 2018: Mayo Clinic Proceedings
https://www.readbyqxmd.com/read/29583037/detection-of-atrial-fibrillation-during-pulpal-blood-flow-assessment-using-doppler-ultrasound-a-case-report
#8
Chan-Hyun Lee, Euiseong Kim, Dohyun Kim
This report describes the case of a 52-year-old male patient who exhibited suspicious pulsation patterns during pulpal blood flow assessment using Doppler ultrasound. Initially, he was not aware of his cardiovascular problem; however, after referral to a medical clinic, he was diagnosed with atrial fibrillation. The patient was injured in a motor vehicle accident and referred to our clinic for management of multiple traumatized teeth. On clinical examination, several teeth exhibited negative responses to cold and electrical sensibility tests...
March 27, 2018: Dento Maxillo Facial Radiology
https://www.readbyqxmd.com/read/29581480/late-cardiovascular-morbidity-and-mortality-following-pediatric-allogeneic-hematopoietic-cell-transplantation
#9
Christine N Duncan, Ruta Brazauskas, Jiaxing Huang, Bronwen E Shaw, Navneet S Majhail, Bipin N Savani, Mary E D Flowers, Minoo Battiwalla, Kristen Beebe, Andrew C Dietz, Christopher C Dvorak, Roger Giller, David A Jacobsohn, Morris Kletzel, Paul L Martin, Eneida R Nemecek, Brandon Nuechterlein, Julie-An Talano, Michael A Pulsipher, K Scott Baker
We analyzed late cardiovascular outcomes of 661 patients who survived at least 2 years from hematopoietic cell transplantation for childhood hematologic malignancy between 1995 and 2008. Center for International Blood and Marrow Transplant Research data was supplemented with surveys focused on cardiotoxicity and potential risk factors. The median duration of follow-up was 97 months (range 24-230). 4.2% of survivors experienced at least one of the primary outcomes including coronary artery disease (0.2%), cerebrovascular accident (0...
March 26, 2018: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/29579808/the-process-of-kidney-donation-in-the-northern-macroregional-area-of-paran%C3%A3-brazil
#10
C Moretti de Souza, I B de Oliveira, M J Quina Galdino, R Gvozd Costa, M Â Rossaneis, M C Fernandez Lourenço Haddad
INTRODUCTION: The high morbidity and mortality caused by chronic kidney disease, and consequently, the increase in the need for kidney transplants, makes the evaluation of the kidney donation process relevant to verifying the service's fragility with the goal of optimizing this process. OBJECTIVE: This study analyzed the process of kidney donation in the Northern Macroregional area of Paraná, Brazil. METHOD: This was a cross-sectional and retrospective evaluation study based on 586 reports of deaths provided by the Intra-Hospital Organ Donation and Transplant Tissue Commissions to the Organ Procurement Organization of the Northern Macroregional area of Paraná in Brazil between 2011 and 2015...
March 2018: Transplantation Proceedings
https://www.readbyqxmd.com/read/29499865/ten-year-clinical-experience-of-humanitarian-cardiothoracic-surgery-in-rwanda-building-a-platform-for-ultimate-sustainability-in-a-resource-limited-setting
#11
JaBaris D Swain, Colleen Sinnott, Suellen Breakey, Rian Hasson Charles, Gita Mody, Napthal Nyirimanzi, Ceeya Patton-Bolman, Patricia Come, Gapira Ganza, Emmanuel Rusingiza, Nathan Ruhamya, Joseph Mucumbitsi, Jorge Borges, Martin Zammert, Jochen D Muehlschlegel, Robert Oakes, Bruce Leavitt, R Morton Bolman
OBJECTIVE: Despite its near complete eradication in resource-rich countries, rheumatic heart disease remains the most common acquired cardiovascular disease in sub-Saharan Africa. With a ratio of physicians/population of 1 per 10,500, including only 4 cardiologists for a population of 11.4 million, Rwanda represents a resource-limited setting lacking the local capacity to detect and treat early cases of strep throat and perform lifesaving operations for advanced rheumatic heart disease...
February 27, 2018: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29480889/cardiovascular-and-cerebrovascular-events-are-associated-with-nontraumatic-osteonecrosis-of-the-femoral-head
#12
Pei-Hsun Sung, Yao-Hsu Yang, Hsin-Ju Chiang, John Y Chiang, Chi-Jen Chen, Hon-Kan Yip, Mel S Lee
BACKGROUND: Endothelial dysfunction has been identified as an etiologic factor for osteonecrosis of the femoral head (ONFH) and major adverse cardiovascular and cerebrovascular events (defined as major cardiovascular disease [CVD] and cerebrovascular accident [CVA]). However, the incidence of major adverse cardiovascular and cerebrovascular events in patients with nontraumatic ONFH and any association between the two diagnoses remain unclear. QUESTIONS/PURPOSES: We compared a large cohort of patients with nontraumatic ONFH and a matched control group without this diagnosis and (1) examined the frequency and hazard ratio (HR) of major adverse cardiovascular and cerebrovascular events in both groups adjusted for age, sex, socioeconomic status, and associated comorbidities (which we defined as the adjusted HR), (2) determined whether any association of ONFH and major adverse cardiovascular and cerebrovascular events was stable after adjusting for confounding variables, and (3) compared the occurrence of major adverse cardiovascular and cerebrovascular events with time in both groups...
April 2018: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/29444688/twenty-years-of-home-based-palliative-care-in-malappuram-kerala-india-a-descriptive-study-of-patients-and-their-care-givers
#13
Rekha Rachel Philip, Sairu Philip, Jaya Prasad Tripathy, Abdulla Manima, Emilie Venables
BACKGROUND: The well lauded community-based palliative care programme of Kerala, India provides medical and social support, through home-based care, for patients with terminal illness and diseases requiring long-term support. There is, however, limited information on patient characteristics, caregivers and programme performance. This study was carried out to describe: i) the patients enrolled in the programme from 1996 to 2016 and their diagnosis, and ii) the care-giver characteristics and palliative care support from nurses and doctors in a cohort of patients registered during 2013-2015...
February 14, 2018: BMC Palliative Care
https://www.readbyqxmd.com/read/29396239/long-term-outcomes-of-new-generation-drug-eluting-stents-versus-coronary-artery-bypass-grafting-for-multivessel-and-or-left-main-coronary-artery-disease-a-bayesian-network-meta-analysis-of-randomized-controlled-trials
#14
George S Mina, Hussam Watti, Demiana Soliman, Anand Shewale, Jessica Atkins, Pratap Reddy, Paari Dominic
BACKGROUND: Most data guiding revascularization of multivessel disease (MVD) and/or left main disease (LMD) favor coronary artery bypass grafting (CABG) over percutaneous coronary intervention (PCI). However, those data are based on trials comparing CABG to bare metal stents (BMS) or old generation drug eluting stents (OG-DES). Hence, it is essential to outcomes of CABG to those of new generation drug eluting stents (NG-DES). METHODS: We searched PUBMED and Cochrane database for trials evaluating revascularization of MVD and/or LMD with CABG and/or PCI...
January 5, 2018: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/29395647/expression-of-connexin43-in-cerebral-arteries-of-patients-with-moyamoya-disease
#15
Jiaqi Liao, Tao Hong, Jinxian Xu, Erming Zeng, Bin Tang, Wentao Lai
BACKGROUND AND PURPOSE: Moyamoya disease has a high incidence of cerebral vascular accident in children and adolescents, which can endanger the physical and mental health of children and adults seriously. However, the etiology and the pathogenesis of moyamoya disease remain unclear. Connexin43 (Cx43) is a predominant intercellular gap junction protein that plays an important role in the normal function of arteries and the development of several cardiovascular diseases. We aimed to preliminarily investigate pathological changes and the expression of Cx43 in cerebral arteries of patients with moyamoya disease...
January 25, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29395493/fibrates-in-the-secondary-prevention-of-cardiovascular-disease-infarction-and-stroke-results-of-a-systematic-review-and-meta-analysis-of-the-cochrane-collaboration
#16
Jesus Millan, Xavier Pintó, Angel Brea, Mariano Blasco, Antonio Hernandez Mijares, Juan Ascaso, Angel Diaz, Teresa Mantilla, Juan Pedro-Botet
Fibrates are a group of drugs that are known mainly for reducing triglycerides, increasing high density lipoproteins (HDL), and reducing the fraction of small, dense LDL particles. The results of a Cochrane Collaboration study have recently been published on their efficacy and safety in the secondary prevention of severe cardiovascular accidents, including coronary and cerebrovascular disease. The study included randomised clinical trials in which the fibrate was compared with placebo or with no treatment. Clinical trials comparing two different fibrates were excluded...
January 30, 2018: Clínica e Investigación en Arteriosclerosis
https://www.readbyqxmd.com/read/29392520/pre-participation-screening-of-asymptomatic-athletes-don-t-do-stupid-stuff
#17
REVIEW
A Mosterd
Catastrophic events, be it traffic accidents, natural disasters or homicides, always lead to scrutiny. Could we have seen the event coming and could it have been prevented? In the case of a sudden cardiac arrest of a seemingly healthy athlete the public outcry is not any different. Despite an intrinsic appeal for screening to prevent similar events, there is no evidence that justifies routine cardiovascular pre-participation screening of athletes. On balance, cardiovascular screening in athletes will most likely do more harm than good...
February 1, 2018: Netherlands Heart Journal
https://www.readbyqxmd.com/read/29371140/the-relationship-between-shift-work-and-men-s-health
#18
REVIEW
Nanfu Deng, Taylor P Kohn, Larry I Lipshultz, Alexander W Pastuszak
BACKGROUND: More than 21 million Americans and nearly 20% of the U.S. workforce are shift workers. Non-standard shift work, defined as work that falls outside of 6 am-6 pm, can lead to poor diet, exercise, and sleep habits that lead to decreased productivity, increased workplace accidents, and a variety of negative health outcomes. AIM: To investigate the associations between shift work exposure and chronic medical conditions such as metabolic syndromes, cardiovascular disease, gastrointestinal disturbances, and depression as well as urologic complications including hypogonadism, male infertility, lower urinary tract symptoms, and prostate cancer with a focus on the effects of shift work sleep disorder (SWSD) on the severity of these negative health outcomes...
January 19, 2018: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/29370191/completeness-and-reliability-of-mortality-data-in-viet-nam-implications-for-the-national-routine-health-management-information-system
#19
Tran Thi Hong, Nguyen Phuong Hoa, Sue M Walker, Peter S Hill, Chalapati Rao
BACKGROUND: Mortality statistics form a crucial component of national Health Management Information Systems (HMIS). However, there are limitations in the availability and quality of mortality data at national level in Viet Nam. This study assessed the completeness of recorded deaths and the reliability of recorded causes of death (COD) in the A6 death registers in the national routine HMIS in Viet Nam. METHODOLOGY AND FINDINGS: 1477 identified deaths in 2014 were reviewed in two provinces...
2018: PloS One
https://www.readbyqxmd.com/read/29366570/off-pump-versus-on-pump-coronary-artery-bypass-grafting-insights-from-the-arterial-revascularization-trial
#20
Umberto Benedetto, Douglas G Altman, Stephen Gerry, Alastair Gray, Belinda Lees, Marcus Flather, David P Taggart
BACKGROUND: The long-term effects of off-pump coronary artery bypass continue to be controversial because some studies have reported increased adverse event rates with off-pump coronary artery bypass when compared with on-pump coronary artery bypass. The Arterial Revascularization Trial compared survival after bilateral versus single internal thoracic artery grafting. The choice of off-pump coronary artery bypass versus on-pump coronary artery bypass was based on the surgeon's discretion...
April 2018: Journal of Thoracic and Cardiovascular Surgery
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