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Haemorrhagic fever

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https://www.readbyqxmd.com/read/28721167/unexplained-haemorrhagic-fever-in-rural-ethiopia
#1
Zegeye Hailemariam, Doreen Tuhebwe, Meeyoung Mattie Park, Casey Daniel Hall
This case study was written based on events of an outbreak investigation of an unfamiliar disease in Ethiopia during October-December 2012. Ethiopia did not have reports of similar cases in the 50 years prior to this outbreak. In this case study, we recapitulate and analyse this outbreak investigation based on data gathered from the community, health facility, and laboratory systems. It can be used to teach: 1) the outbreak investigation process; 2) selection of appropriate epidemiological design for the investigation process, 3) basic statistical analysis of surveillance data, and 4) principals of disease control...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28710823/the-african-swine-fever-epidemic-in-west-africa-1996-2002
#2
REVIEW
A-A Brown, M L Penrith, F O Fasina, D Beltran-Alcrudo
African swine fever (ASF) is a contagious, highly fatal, haemorrhagic viral disease that only affects members of the Suidae family. Currently, no vaccine or treatment exists, so the disease has potentially devastating consequences for the pig industries, availability of affordable protein livelihoods and trade. This study aimed to consolidate historical information generated by working towards the control and eradication of ASF in previously unaffected countries in West Africa during 1996-2002. This descriptive analysis entailed the evaluation and review of archived records and reports of outbreaks, data from veterinary services, veterinary consultants and peer-reviewed publications...
July 14, 2017: Transboundary and Emerging Diseases
https://www.readbyqxmd.com/read/28703073/persistence-of-immune-responses-to-vaccine-against-haemorrhagic-fever-with-renal-syndrome-in-healthy-adults-aged-16-60-years-results-from-an-open-label2-year-follow-up-study
#3
Yuan Zheng, Bu-Yu Zhou, Jing Wei, Yi Xu, Jian-Hua Dong, Lu-Yuan Guan, Ping Ma, Peng-Bo Yu, Jing-Jun Wang
BACKGROUND: Approximately 2 million doses of vaccine against haemorrhagic fever with renal syndrome (HFRS) have been used annually in China. However, there were limited studies focused on persistence of immune responses to HFRS vaccine in healthy adults. A phase 4, multicentre, open trial has been undertaken to assess antibody persistence after HFRS vaccination of healthy adolescents and adults aged 16-60 years. METHODS: The vaccine was administered as a three-dose series at 0, 2 weeks and 6 months, including two primary doses and one booster dose...
July 13, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28698348/determinants-of-mortality-and-prolonged-hospital-stay-among-dengue-patients-attending-tertiary-care-hospital-a-cross-sectional-retrospective-analysis
#4
Tauqeer Hussain Mallhi, Amer Hayat Khan, Azmi Sarriff, Azreen Syazril Adnan, Yusra Habib Khan
OBJECTIVES: Dengue imposes substantial economic, societal and personal burden in terms of hospital stay, morbidity and mortality. Early identification of dengue cases with high propensity of increased hospital stay and death could be of value in isolating patients in need of early interventions. The current study was aimed to determine the significant factors associated with dengue-related prolonged hospitalisation and death. DESIGN: Cross-sectional retrospective study...
July 10, 2017: BMJ Open
https://www.readbyqxmd.com/read/28690743/-knowledge-and-attitudes-of-community-volunteers-on-lassa-and-ebola-viral-haemorrhagic-fevers-in-the-donga-department-north-benin
#5
Cossi Angelo Attinsounon, Cossi Athanase Hounnankan, Comlan Albert Dovonou, Cossi Adébayo Alassani, Sourakatou Salifou
No abstract text is available yet for this article.
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28687403/development-of-vaccines-against-crimean-congo-haemorrhagic-fever-virus
#6
Stuart D Dowall, Miles W Carroll, Roger Hewson
Crimean-Congo haemorrhagic fever virus (CCHFV) is a deadly human pathogen of the utmost seriousness being highly lethal causing devastating disease symptoms that result in intense and prolonged suffering to those infected. During the past 40years, this virus has repeatedly caused sporadic outbreaks responsible for relatively low numbers of human casualties, but with an alarming fatality rate of up to 80% in clinically infected patients. CCHFV is transmitted to humans by Hyalomma ticks and contact with the blood of viremic livestock, additionally cases of human-to-human transmission are not uncommon in nosocomial settings...
July 4, 2017: Vaccine
https://www.readbyqxmd.com/read/28681802/globally-emerging-hantaviruses-an-overview
#7
REVIEW
Sara Chandy, Dilip Mathai
Hantaviruses are known to cause haemorrhagic fever with renal syndrome in Eurasia and hantavirus cardiopulmonary syndrome in the Americas. They are globally emerging pathogens as newer serotypes are routinely being reported. This review discusses hantavirus biology, clinical features and pathogenesis of hantavirus disease, its diagnostics, distribution and mammalian hosts. Hantavirus research in India is also summarised.
April 2017: Indian Journal of Medical Microbiology
https://www.readbyqxmd.com/read/28670863/microbiological-zoonotic-emerging-risks-transmitted-between-livestock-animals-and-humans-2007-2015
#8
REVIEW
M E Filippitzi, T Goumperis, T Robinson, C Saegerman
As part of the Emerging Risk Identification (ERI) activities of the European Food Safety Authority (EFSA), a literature search was conducted to identify the microbiological agents transmitted between livestock animals and humans that have been suggested as having emerged between 2007 and 2015 in peer-reviewed scientific literature published during the same period (2007-2015). According to the criteria set, the search identified seven such zoonotic agents, namely West Nile Fever virus, Rift Valley Fever virus, Crimean-Congo Haemorrhagic Fever virus, Influenza A H1N1 virus, Coxiella burnetii, Streptococcus suis and livestock-associated methicillin-resistant Staphylococcus aureus clonal complex 398...
August 2017: Transboundary and Emerging Diseases
https://www.readbyqxmd.com/read/28669587/therapeutic-management-of-crimean-congo-haemorrhagic-fever
#9
Fernando de la Calle-Prieto, Alejandro Martín-Quirós, Elena Trigo, Marta Mora-Rillo, Marta Arsuaga, Marta Díaz-Menéndez, José Ramón Arribas
Crimean-Congo haemorrhagic fever has been reported in more than 30 countries in Africa, Asia, the Middle East and Eastern Europe, with an increasing incidence in recent years, especially in Europe. Because no specific treatments have demonstrated efficacy, supportive treatment is essential, as well as the provision of a centre with the appropriate means to guarantee the safety of its healthcare professionals. Laboratory monitoring of thrombocytopenia, severe coagulopathy or liver failure is of critical importance...
June 29, 2017: Enfermedades Infecciosas y Microbiología Clínica
https://www.readbyqxmd.com/read/28658761/ebola-vaccine-how-far-are-we
#10
REVIEW
Rajani Sharma, Ketki Jangid, Anuradha
Ebola viruses have been identified as an emerging threat as it causes severe haemorrhagic fever in human with mortality rates ranging from 50 to 90%. In addition to being a global health concern, the virus also is considered a potential biological threat agent. As for now, no licensed vaccine is available for pre or post exposure treatment. Recent epidemic of this disease in South Africa has led to concern towards development of an effective vaccine on a priority basis. This review is an attempt to look upon current progress in the development of Ebola virus vaccines and highlights strategies that have the greatest potential for commercial development...
May 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28653957/the-lifecycle-of-the-ebola-virus-in-host-cells
#11
REVIEW
Dong-Shan Yu, Tian-Hao Weng, Xiao-Xin Wu, Frederick X C Wang, Xiang-Yun Lu, Hai-Bo Wu, Nan-Ping Wu, Lan-Juan Li, Hang-Ping Yao
Ebola haemorrhagic fever causes deadly disease in humans and non-human primates resulting from infection with the Ebola virus (EBOV) genus of the family Filoviridae. However, the mechanisms of EBOV lifecycle in host cells, including viral entry, membrane fusion, RNP formation, GP-tetherin interaction, and VP40-inner leaflet association remain poorly understood. This review describes the biological functions of EBOV proteins and their roles in the lifecycle, summarizes the factors related to EBOV proteins or RNA expression throughout the different phases, and reviews advances with regards to the molecular events and mechanisms of the EBOV lifecycle...
June 15, 2017: Oncotarget
https://www.readbyqxmd.com/read/28651786/autochthonous-crimean-congo-haemorrhagic-fever-in-spain-so-much-to-learn
#12
Marta Mora-Rillo, Marta Díaz-Menéndez, Clara Crespillo-Andujar, Jose R Arribas
No abstract text is available yet for this article.
June 23, 2017: Enfermedades Infecciosas y Microbiología Clínica
https://www.readbyqxmd.com/read/28634581/commentary-surveillance-of-crimean-congo-haemorrhagic-fever-in-pakistan
#13
COMMENT
Tauqeer Hussain Mallhi, Yusra Habib Khan, Nida Tanveer, Amer Hayat Khan, Muhammad Imran Qadir
No abstract text is available yet for this article.
2017: Frontiers in Public Health
https://www.readbyqxmd.com/read/28598047/awareness-and-outcome-of-changing-trends-in-clinical-profile-of-dengue-fever-a-retrospective-analysis-of-dengue-epidemic-from-january-to-december-2014-at-a-tertiary-care-hospital
#14
Jitendra Singh, Anju Dinkar, Virendra Atam, D Himanshu, Kamlesh Kumar Gupta, Kauser Usman, Ravi Misra
BACKGROUND: Dengue fever is caused by mosquito-borne arboviral infection that has become a public health concern globally. Recently, an alarming rise of dengue has also been seen in India. Hence the study was undertaken to know profile of clinical manifestations and laboratory findings during the evolution of dengue fever. METHODS: In this study, retrospective data analysis was done in 216 seropositive dengue patients admitted between January to December 2014 in department of medicine at a north Indian care hospital...
May 2017: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/28592199/diffuse-alveolar-haemorrage-as-initial-presentation-of-systemic-lupus-erythematosus-a-case-report
#15
M E Cucuzza, S D Marino, L Schiavone, P Smilari, F Filosco, P Barone
Diffuse alveolar haemorrhage (DAH) is a rare life-threatening complication of systemic lupus erythematosus (SLE), associated with high mortality rates. It usually occurs in patients with an established diagnosis of SLE. It has been reported as the initial presentation of SLE in 11-20% of cases. It occurs most frequently in females. We describe the case of a child, aged 14 years, with fever, asthenia, haemoptysis, dyspnea, anaemia, increased inflammatory markers, positivity to ANA, nDNA, direct Coombs tests, anticardiolipin antibodies and complement factors consumption...
January 1, 2017: Lupus
https://www.readbyqxmd.com/read/28585306/circulation-and-diagnostics-of-puumala-virus-in-norway-nephropatia-epidemica-incidence-and-rodent-population-dynamics
#16
Natacha Milhano, Lars Korslund, Magnus Evander, Clas Ahlm, Kirsti Vainio, Susanne G Dudman, Åshild Andreassen
Hantaviruses pose a public health concern worldwide causing haemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS). Puumala virus (PUUV) is the most prevalent hantavirus in Central and Northern Europe, and causes a mild form of HFRS, also known as nephropathia epidemica (NE). In nature, the main host of PUUV is the bank vole (Myodes glareolus), and transmission to humans occurs through inhalation of aerosols from rodent excreta. Nephropathia epidemica is particularly prevalent in Nordic countries, however, few studies of PUUV have been performed in Norway...
June 6, 2017: APMIS: Acta Pathologica, Microbiologica, et Immunologica Scandinavica
https://www.readbyqxmd.com/read/28567195/abdominal-myomectomy-a-retrospective-review-of-determinants-and-outcomes-of-complications-at-the-university-of-ilorin-teaching-hospital-ilorin-nigeria
#17
Kikelomo T Adesina, Beatrice O Owolabi, Hadijat O Raji, Adebunmi O Olarinoye
BACKGROUND: The aim of this study was to describe the pattern, outcomes, and determinants of perioperative complications of abdominal myomectomy at the University of Ilorin Teaching Hospital, Ilorin, Nigeria. METHODS: This was a retrospective review of cases of abdominal myomectomy between January 2010 and December 2013. Data were obtained from ward and operating theatre case records and analysed using SPSS version 20. The continuous variables were analysed with Student's t-test...
March 2017: Malawi Medical Journal: the Journal of Medical Association of Malawi
https://www.readbyqxmd.com/read/28545142/the-risk-of-transmission-of-a-viral-haemorrhagic-fever-infection-in-a-united-kingdom-laboratory
#18
Robert J Shorten, Eleri Wilson-Davies
No abstract text is available yet for this article.
May 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28531835/postpartum-acute-colonic-pseudo-obstruction-ogilvie-s-syndrome-a-systematic-review-of-case-reports-and-case-series
#19
REVIEW
Pradeep Jayaram, Manoj Mohan, Stephen Lindow, Justin Konje
INTRODUCTION: Ogilvie's Syndrome or Acute Colonic Pseudo-Obstruction (ACPO) is a rare condition characterized by massive dilatation of the colon in the absence of mechanical obstruction. About 10% of all reported cases are related to Obstetric and Gynaecological procedures, Caesarean section being the commonest associated factor. Acute intestinal dilatation, if not treated, may lead to perforation and faecal peritonitis with consequent high morbidity and mortality. MATERIALS AND METHODS: An electronic literature searches were performed in PubMed, EMBASE, Google scholar and hand searches for relevant references were included without any language restriction...
July 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28529708/yellow-fever-in-the-americas-the-growing-concern-about-new-epidemics
#20
Yeimer Ortiz-Martínez, Andrés Mauricio Patiño-Barbosa, Alfonso J Rodriguez-Morales
Yellow fever (YF) is a haemorrhagic viral disease with a high case fatality rate. It is considered a reemerging infectious disease of remarkable importance. During the last outbreaks in Angola (2015-2016) and Brazil (2016-2017), many cases of YF emerged despite high YF vaccination coverage, increasing the risk of major epidemics in the Americas. Several factors, including the vast border and migratory status of Brazil, the widespread distribution of Aedes mosquitoes and the lack of efficient health policies and surveillance systems, favour this complex epidemiological scenario of reemergence...
2017: F1000Research
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