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Haemorrhagic fever

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https://www.readbyqxmd.com/read/28634581/commentary-surveillance-of-crimean-congo-haemorrhagic-fever-in-pakistan
#1
COMMENT
Tauqeer Hussain Mallhi, Yusra Habib Khan, Nida Tanveer, Amer Hayat Khan, Muhammad Imran Qadir
No abstract text is available yet for this article.
2017: Frontiers in Public Health
https://www.readbyqxmd.com/read/28598047/awareness-and-outcome-of-changing-trends-in-clinical-profile-of-dengue-fever-a-retrospective-analysis-of-dengue-epidemic-from-january-to-december-2014-at-a-tertiary-care-hospital
#2
Jitendra Singh, Anju Dinkar, Virendra Atam, D Himanshu, Kamlesh Kumar Gupta, Kauser Usman, Ravi Misra
BACKGROUND: Dengue fever is caused by mosquito-borne arboviral infection that has become a public health concern globally. Recently, an alarming rise of dengue has also been seen in India. Hence the study was undertaken to know profile of clinical manifestations and laboratory findings during the evolution of dengue fever. METHODS: In this study, retrospective data analysis was done in 216 seropositive dengue patients admitted between January to December 2014 in department of medicine at a north Indian care hospital...
May 2017: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/28592199/diffuse-alveolar-haemorrage-as-initial-presentation-of-systemic-lupus-erythematosus-a-case-report
#3
M E Cucuzza, S D Marino, L Schiavone, P Smilari, F Filosco, P Barone
Diffuse alveolar haemorrhage (DAH) is a rare life-threatening complication of systemic lupus erythematosus (SLE), associated with high mortality rates. It usually occurs in patients with an established diagnosis of SLE. It has been reported as the initial presentation of SLE in 11-20% of cases. It occurs most frequently in females. We describe the case of a child, aged 14 years, with fever, asthenia, haemoptysis, dyspnea, anaemia, increased inflammatory markers, positivity to ANA, nDNA, direct Coombs tests, anticardiolipin antibodies and complement factors consumption...
January 1, 2017: Lupus
https://www.readbyqxmd.com/read/28585306/circulation-and-diagnostics-of-puumala-virus-in-norway-nephropatia-epidemica-incidence-and-rodent-population-dynamics
#4
Natacha Milhano, Lars Korslund, Magnus Evander, Clas Ahlm, Kirsti Vainio, Susanne G Dudman, Åshild Andreassen
Hantaviruses pose a public health concern worldwide causing haemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS). Puumala virus (PUUV) is the most prevalent hantavirus in Central and Northern Europe, and causes a mild form of HFRS, also known as nephropathia epidemica (NE). In nature, the main host of PUUV is the bank vole (Myodes glareolus), and transmission to humans occurs through inhalation of aerosols from rodent excreta. Nephropathia epidemica is particularly prevalent in Nordic countries, however, few studies of PUUV have been performed in Norway...
June 6, 2017: APMIS: Acta Pathologica, Microbiologica, et Immunologica Scandinavica
https://www.readbyqxmd.com/read/28567195/abdominal-myomectomy-a-retrospective-review-of-determinants-and-outcomes-of-complications-at-the-university-of-ilorin-teaching-hospital-ilorin-nigeria
#5
Kikelomo T Adesina, Beatrice O Owolabi, Hadijat O Raji, Adebunmi O Olarinoye
BACKGROUND: The aim of this study was to describe the pattern, outcomes, and determinants of perioperative complications of abdominal myomectomy at the University of Ilorin Teaching Hospital, Ilorin, Nigeria. METHODS: This was a retrospective review of cases of abdominal myomectomy between January 2010 and December 2013. Data were obtained from ward and operating theatre case records and analysed using SPSS version 20. The continuous variables were analysed with Student's t-test...
March 2017: Malawi Medical Journal: the Journal of Medical Association of Malawi
https://www.readbyqxmd.com/read/28545142/the-risk-of-transmission-of-a-viral-haemorrhagic-fever-infection-in-a-united-kingdom-laboratory
#6
Robert J Shorten, Eleri Wilson-Davies
No abstract text is available yet for this article.
May 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28531835/postpartum-acute-colonic-pseudo-obstruction-ogilvie-s-syndrome-a-systematic-review-of-case-reports-and-case-series
#7
REVIEW
Pradeep Jayaram, Manoj Mohan, Stephen Lindow, Justin Konje
INTRODUCTION: Ogilvie's Syndrome or Acute Colonic Pseudo-Obstruction (ACPO) is a rare condition characterized by massive dilatation of the colon in the absence of mechanical obstruction. About 10% of all reported cases are related to Obstetric and Gynaecological procedures, Caesarean section being the commonest associated factor. Acute intestinal dilatation, if not treated, may lead to perforation and faecal peritonitis with consequent high morbidity and mortality. MATERIALS AND METHODS: An electronic literature searches were performed in PubMed, EMBASE, Google scholar and hand searches for relevant references were included without any language restriction...
July 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28529708/yellow-fever-in-the-americas-the-growing-concern-about-new-epidemics
#8
Yeimer Ortiz-Martínez, Andrés Mauricio Patiño-Barbosa, Alfonso J Rodriguez-Morales
Yellow fever (YF) is a haemorrhagic viral disease with a high case fatality rate. It is considered a reemerging infectious disease of remarkable importance. During the last outbreaks in Angola (2015-2016) and Brazil (2016-2017), many cases of YF emerged despite high YF vaccination coverage, increasing the risk of major epidemics in the Americas. Several factors, including the vast border and migratory status of Brazil, the widespread distribution of Aedes mosquitoes and the lack of efficient health policies and surveillance systems, favour this complex epidemiological scenario of reemergence...
2017: F1000Research
https://www.readbyqxmd.com/read/28499011/fatal-case-of-chikungunya-and-concomitant-thrombotic-thrombocytopenic-purpura-in-french-guiana-during-air-flight-medical-evacuation
#9
Loïc Epelboin, Bastien Bidaud, Emilie Mosnier, Paul Le Turnier, Guillaume Vesin, Gaëlle Walter, Philippe Abboud, Stéphanie Houcke, Maïa Forgues, Gérald Egmann, Alain Stepanian, Félix Djossou
Thrombotic thrombocytopenic purpura (TTP) is a thrombotic microangiopathy associated to severe ADAMTS13 deficiency. It has been linked to various viral infections. Among arboviruses, only Crimean-Congo haemorrhagic fever and dengue fever have been linked to this severe disease. We report the first documented case of TTP concomitant to Chikungunya virus infection.
September 1, 2017: Journal of Travel Medicine
https://www.readbyqxmd.com/read/28488954/isolation-of-a-novel-orthobunyavirus-from-bat-flies-eucampsipoda-africana
#10
Petrus Jansen van Vuren, Michael R Wiley, Gustavo Palacios, Nadia Storm, Wanda Markotter, Monica Birkhead, Alan Kemp, Janusz T Paweska
The Bunyaviridae family comprises viruses causing diseases of public and veterinary health importance, including viral haemorrhagic and arboviral fevers. We report the isolation, identification and genome characterization of a novel orthobunyavirus, named Wolkberg virus (WBV), from wingless bat fly ectoparasites (Eucampsipoda africana) of Egyptian fruit bats (Rousettus aegyptiacus) in South Africa. Complete genome sequence data of WBV suggests it is most closely related to two bat viruses (Mojuí dos Campos and Kaeng Khoi viruses) and an arbovirus (Nyando virus) previously shown to infect humans...
May 11, 2017: Journal of General Virology
https://www.readbyqxmd.com/read/28466055/crimean-congo-hemorrhagic-fever-cases-in-the-north-of-iran-have-three-distinct-origins
#11
Nariman Shahhosseini, Sadegh Chinikar, Elnaz Shams, Norbert Nowotny, Anthony R Fooks
An on-going surveillance program on Crimean-Congo haemorrhagic fever virus (CCHFV) in Iran has been launched since 2000. An outbreak of CCHF occurred in northern Iran between June and July 2015. Three cases were involved in this outbreak. One patient died after admission to hospital, and the others were treated successfully. Phylogenetic analysis showed that three sequences obtained from Iranian patients grouped within clade IV (Asia-1), clade V (Europe) and clade VI (Greece). The partial sequence of the strain Noshahr59 (KT588642) showed the highest similarity with other strains isolated from Russia, Kosovo and Turkey (Clade V, Europe)...
March 2017: Virusdisease
https://www.readbyqxmd.com/read/28449693/no-measurable-adverse-effects-of-lassa-morogoro-and-gairo-arenaviruses-on-their-rodent-reservoir-host-in-natural-conditions
#12
Joachim Mariën, Benny Borremans, Sophie Gryseels, Barré Soropogui, Luc De Bruyn, Gédéon Ngiala Bongo, Beate Becker-Ziaja, Joëlle Goüy de Bellocq, Stephan Günther, N'Faly Magassouba, Herwig Leirs, Elisabeth Fichet-Calvet
BACKGROUND: In order to optimize net transmission success, parasites are hypothesized to evolve towards causing minimal damage to their reservoir host while obtaining high shedding rates. For many parasite species however this paradigm has not been tested, and conflicting results have been found regarding the effect of arenaviruses on their rodent host species. The rodent Mastomys natalensis is the natural reservoir host of several arenaviruses, including Lassa virus that is known to cause Lassa haemorrhagic fever in humans...
April 27, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28437586/pathogenesis-of-vascular-leak-in-dengue-virus-infection
#13
REVIEW
Gathsaurie Neelika Malavige, Graham S Ogg
Endothelial dysfunction leading to vascular leak is the hallmark of severe dengue. Vascular leak typically becomes clinically evident 3-6 days after the onset of illness, which is known as the critical phase. This critical phase follows the period of peak viraemia, and lasts for 24-48 hr and usually shows rapid and complete reversal, suggesting that it is likely to occur as a result of inflammatory mediators, rather than infection of the endothelium. Cytokines such as tumour necrosis factor-α, which are known to be elevated in the critical phase of dengue, are likely to be contributing factors...
July 2017: Immunology
https://www.readbyqxmd.com/read/28424792/sustained-high-levels-of-both-total-and-high-molecular-weight-adiponectin-in-plasma-during-the-convalescent-phase-of-haemorrhagic-fever-with-renal-syndrome-are-associated-with-disease-severity
#14
Kang Tang, Chunmei Zhang, Yusi Zhang, Yun Zhang, Ran Zhuang, Boquan Jin, Ying Ma
Haemorrhagic fever with renal syndrome (HFRS) is characterised by an uncontrolled immune response that causes vascular leakage. Adiponectin (APN) is an adipocytokine involved in prorevascularisation and immunomodulation. To investigate the possible effects of APN in the pathogenesis of HFRS, total and high molecular weight (HMW) APN levels in the plasma of patients with HFRS were quantified using enzyme-linked immunosorbent assay (ELISA). Compared with those in healthy controls, the plasma total and HMW APN levels in patients were elevated to different degrees from the fever onset and remained high at the convalescent phase...
2017: Journal of Immunology Research
https://www.readbyqxmd.com/read/28424030/expanded-dengue-syndrome-three-concomitant-uncommon-presentations-in-the-same-patient
#15
Ahmad Mursel Anam, Raihan Rabbani, Farzana Shumy
We report a case of expanded dengue syndrome, where three uncommon presentations occurred concomitantly. A patient with dengue haemorrhagic fever presented initially with acute acalculous cholecystitis along with acute pancreatitis, but later on, during resolution of pancreatitis and cholecystitis, developed pancytopenia, most likely due to haemophagocytic syndrome. Such presentations, besides being rare themselves, have not been reported to occur concomitantly, in the same patient, during the same disease process...
April 2017: Tropical Doctor
https://www.readbyqxmd.com/read/28403751/management-of-dengue-in-australian-travellers-a-retrospective-multicentre-analysis
#16
MULTICENTER STUDY
Alex Yc Tai, Sarah L McGuinness, Roselle Robosa, David Turner, G Khai Lin Huang, Karin Leder, Tony M Korman, Irani Thevarajan, Andrew J Stewardson, Alexander A Padiglione, Douglas F Johnson
OBJECTIVES: To describe the epidemiology, clinical and laboratory features and outcomes of dengue in returned Australian travellers, applying the revised WHO dengue classification (2009) to this population. DESIGN, SETTING AND PARTICIPANTS: Retrospective case series analysis of confirmed dengue cases hospitalised at one of four Australian tertiary hospitals, January 2012 - May 2015. MAIN OUTCOME MEASURES: Clinical features, laboratory findings and outcomes of patients with dengue; dengue classification according to 2009 WHO guidelines...
April 17, 2017: Medical Journal of Australia
https://www.readbyqxmd.com/read/28402024/marburg-virus-like-particles-produced-in-insect-cells-induce-neutralizing-antibodies-in-rhesus-macaques
#17
Weiwei Gai, Xuexing Zheng, Chong Wang, Yongkun Zhao, Qi Wang, Hualei Wang, Gary Wong, Ying Xie, Haijun Wang, Zengguo Cao, Na Feng, Hang Chi, Tiecheng Wang, Yuwei Gao, Junjie Shan, Songtao Yang, Xianzhu Xia
Marburg virus (MARV), which is one of the most virulent agents in the world, causes lethal haemorrhagic fever in humans and nonhuman primates (NHPs) with a mortality rate of up to 90%. Currently, there is no effective treatment or approved vaccine for MARV for human use to control disease outbreak and spread. Virus-like particles (VLPs), which are morphologically identical to the native infectious virus particle, are efficacious as vaccines against many viruses, including human papilloma virus (HPV), porcine circovirus (PCV) type 2 and hepatitis B virus (HBV)...
April 12, 2017: Journal of Medical Virology
https://www.readbyqxmd.com/read/28397519/emerging-vector-borne-diseases-in-dromedaries-in-tunisia-west-nile-bluetongue-epizootic-haemorrhagic-disease-and-rift-valley-fever
#18
Thameur B Hassine, Jihane Amdouni, Federica Monaco, Giovanni Savini, Soufien Sghaier, Imed B Selimen, Walid Chandoul, Khaled B Hamida, Salah Hammami
A total of 118 sera were collected during 2016 from two groups of dromedaries from Kebili and Medenine governorates in the south of Tunisia. The aim of this study was to provide the first serological investigation of four emerging vector-borne diseases in two groups of dromedaries in Tunisia. Sera were tested by ELISA and serum neutralisation test to identify West Nile virus (WNV), bluetongue virus (BTV), epizootic haemorrhagic disease virus (EHDV) and Rift Valley fever virus (RVFV). In the first group, the seroprevalence for BTV was 4...
March 31, 2017: Onderstepoort Journal of Veterinary Research
https://www.readbyqxmd.com/read/28396469/the-ebola-outbreak-2013-2016-old-lessons-for-new-epidemics
#19
REVIEW
Cordelia E M Coltart, Benjamin Lindsey, Isaac Ghinai, Anne M Johnson, David L Heymann
Ebola virus causes a severe haemorrhagic fever in humans with high case fatality and significant epidemic potential. The 2013-2016 outbreak in West Africa was unprecedented in scale, being larger than all previous outbreaks combined, with 28 646 reported cases and 11 323 reported deaths. It was also unique in its geographical distribution and multicountry spread. It is vital that the lessons learned from the world's largest Ebola outbreak are not lost. This article aims to provide a detailed description of the evolution of the outbreak...
May 26, 2017: Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
https://www.readbyqxmd.com/read/28396468/a-review-of-phase-i-trials-of-ebola-virus-vaccines-what-can-we-learn-from-the-race-to-develop-novel-vaccines
#20
REVIEW
Teresa Lambe, Georgina Bowyer, Katie J Ewer
Sporadic outbreaks of Ebola virus infection have been documented since the mid-Seventies and viral exposure can lead to lethal haemorrhagic fever with case fatalities as high as 90%. There is now a comprehensive body of data from both ongoing and completed clinical trials assessing various vaccine strategies, which were rapidly advanced through clinical trials in response to the 2013-2016 Ebola virus disease (EVD) public health emergency. Careful consideration of immunogenicity post vaccination is essential but has been somewhat stifled because of the wide array of immunological assays and outputs that have been used in the numerous clinical trials...
May 26, 2017: Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
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