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Alcohol allergy

Monica Corazza, Annarosa Virgili, Michela Ricci, Anna Bianchi, Alessandro Borghi
BACKGROUND: The evidence on the safety of topical preparations containing emulsifiers is limited. OBJECTIVES: The aims of the study were to assess (1) the prevalence of sensitization to some emulsifiers commonly found in topical products, (2) the sensitization to emulsifiers in relation to sex, age, and predisposing factors, and (3) the frequency of concomitant sensitization to other common allergens. METHODS: All consecutive patients presenting to the Allergy Unit of our Dermatological Department for allergological investigation were enrolled...
September 2016: Dermatitis
L D Buirs, L W A H Van Beers, V A B Scholtes, T Pastoors, S Sprague, R W Poolman
OBJECTIVE: The objective of this systematic review of the literature was to identify the predictors of functional outcome after total hip arthroplasty (THA). METHOD: A systematic literature search in Web of Science, CINAHL, EMBASE and PubMed was conducted on 23 June 2015. The articles were selected based on their quality, relevance and measurement of the predictive factor. The level of evidence of all studies was determined using the GRADE rating scheme. RESULTS: The initial search resulted in 1092 citations...
2016: BMJ Open
Ine I Decuyper, Athina L Van Gasse, Nathalie Cop, Vito Sabato, Margaretha Faber, Christel Mertens, Chris H Bridts, Margo M Hagendorens, Luc De Clerck, H P Rihs, Didier G Ebo
IgE-mediated Cannabis (C. sativa, marihuana) allergy seems to be on the rise. Both active and passive exposure to cannabis allergens may trigger a C. sativa sensitization and/or allergy. The clinical presentation of a C. sativa allergy varies from mild to life-threatening reactions and often seems to depend on the route of exposure. In addition, sensitization to cannabis allergens can result in various cross-allergies, mostly for plant foods. This clinical entity, designated as the "cannabis-fruit/vegetable syndrome" might also imply cross-reactivity with tobacco, natural latex and plant-food derived alcoholic beverages...
September 3, 2016: Allergy
Wolfgang Uter, Radoslaw Spiewak, Susan M Cooper, Mark Wilkinson, Javier Sánchez Pérez, Axel Schnuch, Marie-Louise Schuttelaar
PURPOSE: The aim of this study was to give an overview of the prevalence of contact allergy to active ingredients and excipients of topical medications across Europe. METHODS: Retrospective analysis of data collected by the European Surveillance System on Contact Allergies ( with substances applied to consecutively patch tested patients, 2009-2012, in 54 departments in 12 European countries. RESULTS: In view of the varying composition of the baseline series used in the previously mentioned departments and countries, between 58 833 (lanolin alcohols) and 16 498 patients (sodium metabisulfite) were patch tested with the topical agents covered in this study...
July 28, 2016: Pharmacoepidemiology and Drug Safety
Hsiao-Chen Liao, Shang-Yin Wu, Chun-Yen Ou, Jenn-Ren Hsiao, Jehn-Shyun Huang, Sen-Tien Tsai, Cheng-Chih Huang, Tung-Yiu Wong, Wei-Ting Lee, Ken-Chung Chen, Sheen-Yie Fang, Jiunn-Liang Wu, Tze-Ta Huang, Yuan-Hua Wu, Wei-Ting Hsueh, Chia-Jui Yen, Ming-Wei Yang, Forn-Chia Lin, Yu-Hsuan Lai, Jang-Yang Chang, Chen-Lin Lin, Yi-Hui Wang, Ya-Ling Weng, Han-Chien Yang, Yu-Shan Chen, Jeffrey S Chang
PURPOSE: Allergy symptoms have been associated with a reduced head and neck cancer (HNC) risk, while elevated blood immunoglobulin E (IgE) levels have been associated with an increased HNC risk. According to the "prophylaxis hypothesis," allergic reaction is the body's way of expelling carcinogens. IgE level may be increased by exposure to environmental carcinogens, including alcohol and cigarette smoke. We hypothesized that individuals with elevated serum IgE without allergy symptoms (i...
September 2016: Cancer Causes & Control: CCC
Claire L Higgins, Amanda M Palmer, Jennifer L Cahill, Rosemary L Nixon
BACKGROUND: Healthcare workers (HCWs) are at risk of developing occupational skin disease (OSD). OBJECTIVES: To ascertain the causes of OSD in Australian HCWs in a tertiary referral clinic. METHODS: A retrospective review was performed of patients assessed at the Occupational Dermatology Clinic in Melbourne from 1993 to 2014. RESULTS: Of 685 HCWs assessed in the clinic over a period of 22 years, 555 (81.0%) were diagnosed with OSD...
October 2016: Contact Dermatitis
Juan H Macias, Mildred F Alvarez, Virginia Arreguin, Juan M Muñoz, Alejandro E Macias, Jose A Alvarez
BACKGROUND: We do not know whether differences exist between the residual effect of 2% chlorhexidine in 70% isopropyl alcohol when compared with 1% triclosan in 70% isopropyl alcohol. METHODS: Using an analytic, longitudinal, controlled, and comparative experimental trial, with blinded measurements, we recruited healthy, adult volunteers from the University of Guanajuato who completed a stabilization phase of skin microbiota and had no history of skin allergies...
June 30, 2016: American Journal of Infection Control
Dubravko Habek, Tatjana Dujaković, Jasna Cerkez Habek, Ivana Jurković
Results of the first research of this kind on the 23-year long-term outcome in children born during the war in Vukovar are presented. This retrospective clinical study surveyed the potential 23-year long-term consequences and morbidity of children born between May 1, 1991 and November 19, 1991, during the siege and occupation of Vukovar. Data were obtained from women having delivered their babies in that period and from delivery protocols of the Department of Gynecology and Obstetrics, Vukovar County Hospital...
March 2016: Acta Clinica Croatica
Eric Moss, Camille Debeuckelaere, Valérie Berl, Karim Elbayed, François-Marie Moussallieh, Izzie-Jacques Namer, J-P Lepoittevin
Chemical modification of epidermal proteins by skin sensitizers is the molecular event which initiates the induction of contact allergy. However, not all chemical skin allergens react directly as haptens with epidermal proteins but need either a chemical (prehaptens) or metabolic (prohaptens) activation step to become reactive. Cinnamyl alcohol has been considered a model prohapten, as this skin sensitizer has no intrinsic reactivity. Therefore, the prevailing theory is that cinnamyl alcohol is enzymatically oxidized into the protein-reactive cinnamaldehyde, which is the sensitizing agent...
July 18, 2016: Chemical Research in Toxicology
S Chinnaswamy
Interferon (IFN) lambda (IFN-λ or type III IFN) gene polymorphisms were discovered in the year 2009 to have a strong association with spontaneous and treatment-induced clearance of hepatitis C virus (HCV) infection in human hosts. This landmark discovery also brought renewed interest in type III IFN biology. After more than half a decade since this discovery, we now have reports that show that genetic association of IFNL gene polymorphisms in humans is not limited only to HCV infections but extends beyond, to include varied diseases such as non-alcoholic fatty liver disease, allergy and several other viral diseases including that caused by the human immunodeficiency virus...
July 2016: Genes and Immunity
Minna E Kubin, Riitta Riekki
No abstract text is available yet for this article.
July 2016: Contact Dermatitis
Małgorzata Kucharska, Wiktor Wesołowski, Sławomir Czerczak, Renata Soćko
BACKGROUND: Electronic cigarettes are currently in common use. However, in Poland there is no specific legislation governing the sale of these products. At the same time, no information has been made public about the hazards e-cigarettes pose to the users and bystanders - passive smokers. The aim of the study was to determine the qualitative composition of the analyzed liquid, which is an essential element of regulating the distribution of such cigarettes. MATERIAL AND METHODS: Under this study the method for determining the composition of e-cigarette liquids was developed...
2016: Medycyna Pracy
Keiko Wada, Kie Konishi, Takashi Tamura, Makoto Shiraki, Shinichi Iwasa, Chisato Nagata
BACKGROUND: Although alcohol consumption has been suggested to have an effect on the immune system, it is unknown whether alcohol consumption has a role in developing allergic diseases. We aimed to examine the associations of total alcohol intake during pregnancy with the risks of childhood asthma and atopic eczema in a birth cohort in Japan. METHODS: Pregnant women were recruited at a maternal clinic from May 2000 to October 2001. The children who were born to these mothers were followed until November 2007...
May 2016: Alcoholism, Clinical and Experimental Research
Kofi Asiedu, Samuel Kyei, Frank Boampong, Stephen Ocansey
BACKGROUND: To estimate the prevalence and risk factors of symptomatic dry eye disease (DED) among undergraduate students in a Ghanaian university. METHODS: This cross-sectional study included 700 undergraduate students of the University of Cape Coast, aged 18 to 34 years. Participants completed questionnaires delivered directly to randomly and systematically selected subjects to detect symptomatic dry eye and its predictive factors. Symptomatic dry eye was defined as any reported symptom on the Standard Patient Evaluation Eye Dryness (SPEED) questionnaire reported as often or constant or if any symptom on the Ocular Surface Disease Index (OSDI) was reported as most of the time or all of the time...
March 9, 2016: Eye & Contact Lens
Patnapa Vejanurug, Poohglin Tresukosol, Praneet Sajjachareonpong, Pailin Puangpet
BACKGROUND: In 2003, the EU Cosmetics Directive stated that 26 fragrance substances must be listed on the cosmetic product ingredient labels. Not all of these 26 fragrance substances are detected by the usual screening markers comprising fragrance mix I, fragrance mix II, and Myroxylon pereirae. OBJECTIVES: To evaluate the usefulness of testing with the 26 individual fragrance substances in addition to the standard fragrance screening markers. MATERIALS AND METHODS: Three hundred and twelve consecutive patients were patch tested with our baseline series and the 26 specific fragrance substances required to be declared on cosmetic product ingredient labels in accordance with the EU Cosmetics Directive...
April 2016: Contact Dermatitis
Mary Pat McKay, Loren Groff
UNLABELLED: Use of over-the-counter, prescription, and illicit drugs is increasing in the United States (US). Many of these drugs are psychoactive and can affect the user's ability to safely operate a vehicle. However, data about drug use by vehicle operators is typically limited to a small proportion of operators and a short list of drugs. For instance, required testing for commercial vehicle operators following most accidents is limited to a urine test for 11 drugs. By comparison, the Federal Aviation Administration (FAA), routinely tests fatally injured pilots' blood and tissues for hundreds of compounds...
May 2016: Accident; Analysis and Prevention
Hanan A Merey, Sally S El-Mosallamy, Nagiba Y Hassan, Badr A El-Zeany
Fluticasone propionate (FLU) and Azelastine hydrochloride (AZE) are co-formulated with phenylethyl alcohol (PEA) and Benzalkonium chloride (BENZ) (as preservatives) in pharmaceutical dosage form for treatment of seasonal allergies. Different spectrophotometric methods were used for the simultaneous determination of cited drugs in the dosage form. Direct spectrophotometric method was used for determining of AZE, while Derivative of double divisor of ratio spectra (DD-RS), Ratio subtraction coupled with ratio difference method (RS-RD) and Mean centering of the ratio spectra (MCR) are used for the determination of FLU...
May 5, 2016: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
Iago Carballo, Lucía Alvela, Luis-Fernando Pérez, Francisco Gude, Carmen Vidal, Manuela Alonso, Bernardo Sopeña, Arturo Gonzalez-Quintela
BACKGROUND AND AIM: Serum IgG4 concentrations are commonly measured in clinical practice. The aim of this study was to investigate serum IgG4 concentrations in adults and their potential relationship with demographic, lifestyle, metabolic, and allergy-related factors. METHODS: Serum IgG4 concentrations were measured with a commercial assay in 413 individuals (median age 55 years, 45% males) who were randomly selected from a general adult population. RESULTS: Median IgG4 concentration was 26...
2016: PloS One
Erika Jensen-Jarolim, Franziska Roth-Walter, Erich Leitner, Stefan Buchleitner, Harald Vogelsang, Tamar Kinaciyan
BACKGROUND: Cinnamon aldehyde (alias cinnamaldehyde) is widely used in food, textile or cosmetic industry. It is mostly associated with contact allergy, but immediate type allergies have been reported. The present study was triggered by a case of anaphylactic events to cinnamon in food and upon skin prick test. We investigated a possible correlation of exposure to a disco fog machine and/or shisha consumption with immediate type hypersensitivity to cinnamon aldehyde in the patient and healthy volunteers...
2016: World Allergy Organization Journal
Miriam M Calkins, Tania Busch Isaksen, Benjamin A Stubbs, Michael G Yost, Richard A Fenske
BACKGROUND: Exposure to excessive heat kills more people than any other weather-related phenomenon, aggravates chronic diseases, and causes direct heat illness. Strong associations between extreme heat and health have been identified through increased mortality and hospitalizations and there is growing evidence demonstrating increased emergency department visits and demand for emergency medical services (EMS). The purpose of this study is to build on an existing regional assessment of mortality and hospitalizations by analyzing EMS demand associated with extreme heat, using calls as a health metric, in King County, Washington (WA), for a 6-year period...
2016: Environmental Health: a Global Access Science Source
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