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https://www.readbyqxmd.com/read/29779838/continuing-to-work-with-a-sterile-thumb-splint-a-case-report
#1
S Roner, P Fürnstahl, A Schweizer, K Wieser
Nonoperative treatment of an injured ulnar collateral ligament of the thumb metacarpophalangeal (MCP) joint (skier's thumb without a Stener lesion) is managed by immobilization. A splint is applied on the radial side with the thumb in slight flexion to immobilize the MCP joint and allow motion in the interphalangeal joint. Thermoplastic splints are mainly used for daily activities with the advantage of custom fabrication for optimal comfort. To immobilize the thumb during surgical procedures performed by an orthopedic surgeon, splints made of sterilizable materials are needed but not yet available to our knowledge...
May 17, 2018: Hand Surgery and Rehabilitation
https://www.readbyqxmd.com/read/29778906/percutaneous-sonographically-assisted-endoscopic-gastrostomy-for-difficult-cases-with-interposed-organs
#2
Yoshihiro Moriwaki, Jun Otani, Junzo Okuda, Hitomi Zotani, So Kasuga
OBJECTIVES: The aim of this retrospective observational study was to clarify the usefulness and safety of percutaneous sonographically assisted endoscopic gastrostomy or duodenostomy (PSEGD) using the introduction method. METHODS: The information for the sequential 22 patients who could not undergo standard percutaneous endoscopic gastrostomy (PEG) and underwent PSEGD for 3 y was extracted and was reviewed. In standard PEG, we performed pushing out of the stomach from the mediastinum and full distention to adhere the gastric wall to the peritoneal wall without interposing of the intraperitoneal tissues by air inflation and a turning-over procedure of the endoscope, four-point square fixation of the stomach to the peritoneal wall by using a Funada-style gastric wall fixation kit under diaphanoscopy, extracorporeal thumb pushing, and in difficult cases extracorporeal ultrasound guidance, and if necessary confirmation of fixation of the gastric wall to the peritoneal wall and placement of the PEG tube without any interposed tissues by using ultrasound...
March 27, 2018: Nutrition
https://www.readbyqxmd.com/read/29778590/sternoclavicular-joint-palpation-pain-the-shoulder-s-waddell-sign
#3
Brent A Ponce, Adam T Archie, Shawna L Watson, Parke W Hudson, Mariano E Menendez, Gerald McGwin, Eugene W Brabston
BACKGROUND: Pain is a complex and subjective reality and can be magnified by nonorganic or nonanatomic sources. Multiple studies have demonstrated a correlation between psychological factors and patients' perceptions of musculoskeletal pain and disability. In addition, nonorganic findings as part of the physical examination are well and long recognized. The purpose of this study was to analyze the relationship between a shoulder examination test, palpation of the sternoclavicular joint (SCJ), and psychosocial conditions including chronic pain, depression, and anxiety...
May 16, 2018: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/29777748/a-brief-practical-review-of-size-exclusion-chromatography-rules-of-thumb-limitations-and-troubleshooting
#4
REVIEW
Richard R Burgess
Through years of research, teaching, troubleshooting, and editing, I have developed a solid working understanding of many aspects of protein purification and protein biochemistry. I have also found that many researchers do not understand the basics, let alone the pitfalls, of the techniques they use. In the case of size exclusion chromatography (SEC), I summarize below some of the rules of thumb, suggestions, limitations and troubleshooting I have found most useful in helping my students and colleagues carry out successful SEC...
May 16, 2018: Protein Expression and Purification
https://www.readbyqxmd.com/read/29776723/outcome-of-a-hand-orthosis-and-hand-therapy-for-carpometacarpal-osteoarthritis-in-daily-practice-a-prospective-cohort-study
#5
Jonathan Tsehaie, Kim R Spekreijse, Robbert M Wouters, Harm P Slijper, Reinier Feitz, Steven E R Hovius, Ruud W Selles
PURPOSE: Initial treatment for symptomatic carpometacarpal (CMC) osteoarthritis (OA) of the thumb is usually nonsurgical. However, evidence on the effect of a hand orthosis and hand therapy for mid- and long-term results is limited, and it is unknown how many patients undergo additional surgical treatment. Therefore, the aim of this study is to describe the outcome of a hand orthosis and hand therapy for CMC OA in a large cohort study, and to evaluate the conversion rate to surgical treatment...
May 15, 2018: Journal of Hand Surgery
https://www.readbyqxmd.com/read/29770175/neurologic-complications-in-common-wrist-and-hand-surgical-procedures
#6
Nicole Verdecchia, Julie Johnson, Mark Baratz, Steven Orebaugh
Nerve dysfunction after upper extremity orthopedic surgery is a recognized complication, and may result from a variety of different causes. Hand and wrist surgery require incisions and retraction that necessarily border on small peripheral nerves, which may be difficult to identify and protect with absolute certainty. This article reviews the rates and ranges of reported nerve dysfunction with respect to common surgical interventions for the distal upper extremity, including wrist arthroplasty, wrist arthrodesis, wrist arthroscopy, distal radius open reduction and internal fixation, carpal tunnel release, and thumb carpometacarpal surgery...
March 29, 2018: Orthopedic Reviews
https://www.readbyqxmd.com/read/29768060/seek-and-destroy-improving-pk-pd-profiles-of-anticancer-agents-with-nanoparticles
#7
Anne Rodallec, Raphaelle Fanciullino, Bruno Lacarelle, Joseph Ciccolini
The Pharmacokinetics/pharmacodynamics (PK/PD) relationships with cytotoxics are usually based on a steepening concentration-effect relationship; the greater the drug amount, the greater the effect. The Maximum Tolerated Dose paradigm, finding the balance between efficacy while keeping toxicities at their manageable level, has been the rule of thumb over the last 50-years. Developing nanodrugs is an appealing strategy to help broaden this therapeutic window. The fact that efficacy and toxicity with cytotoxics are intricately linked is primarily due to the complete lack of specificity towards the tumor tissue during their distribution phase...
May 16, 2018: Expert Review of Clinical Pharmacology
https://www.readbyqxmd.com/read/29765192/pinch-aperture-proprioception-reliability-and-feasibility-study
#8
Abdalghani Yahya, Timothy von Behren, Shira Levine, Marcio Dos Santos
[Purpose] To establish the reliability and feasibility of a novel pinch aperture device to measure proprioceptive joint position sense. [Subjects and Methods] Reliability of the pinch aperture device was assessed in 21 healthy subjects. Following familiarization with a 15° target position of the index finger and thumb, subjects performed 5 trials in which they attempted to actively reproduce the target position without visual feedback. This procedure was repeated at a testing session on a separate date, and the between-session intraclass correlation coefficient (ICC) was calculated...
May 2018: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/29764283/minimally-invasive-thread-trigger-digit-release-a-preliminary-report-on-34-digits-of-the-adult-hands
#9
Danqing Guo, Logan McCool, Alexander Senk, Brionn Tonkin, Joseph Guo, Rachel M Lytie, Danzhu Guo
The trigger finger release was performed in 34 digits (11 thumbs and 23 fingers) of 24 patients through the thread transecting technique with the tip-to-tip approach, in which a 22-gauge needle inserts into a 18-gauge needle when both needles are inside the hand, guiding the 22-gauge needle to exit the hand at the same access point of 18-gauge needle. We prospectively evaluated the effectiveness and functional recovery of these patients. In all 34 digits, triggering and locking were resolved, and complete extension and flexion occurred immediately following the release...
January 1, 2018: Journal of Hand Surgery, European Volume
https://www.readbyqxmd.com/read/29761084/options-for-dealing-with-pressure-dependence-of-pulse-wave-velocity-as-a-measure-of-arterial-stiffness-an-update-of-cardio-ankle-vascular-index-cavi-and-cavi0
#10
REVIEW
Bart Spronck, Tammo Delhaas, Mark Butlin, Koen D Reesink, Alberto P Avolio
Pulse wave velocity (PWV), a marker of arterial stiffness, is known to change instantaneously with changes in blood pressure. In this mini-review, we discuss two main approaches for handling the blood pressure dependence of PWV: (1) converting PWV into a pressure-independent index, and (2) correcting PWV per se for the pressure dependence. Under option 1, we focus on cardio-ankle vascular index (CAVI). CAVI is essentially a form of stiffness index β - CAVI is estimated for a (heart-to-ankle) trajectory, whereas β is estimated for a single artery from pressure and diameter measurements...
March 2018: Pulse (Basel, Switzerland)
https://www.readbyqxmd.com/read/29760647/discrimination-and-recognition-of-phantom-finger-sensation-through-transcutaneous-electrical-nerve-stimulation
#11
Mengnan Li, Dingguo Zhang, Yao Chen, Xinyu Chai, Longwen He, Ying Chen, Jinyao Guo, Xiaohong Sui
Tactile sensory feedback would make a significant contribution to the state-of-the-art prosthetic hands for achieving dexterous manipulation over objects. Phantom finger sensation, also called referred sensation of lost fingers, can be noninvasively evoked by transcutaneous electrical nerve stimulation (TENS) of the phantom finger territories (PFTs) near the stump for upper-limb amputees. As such, intuitive sensations pertaining to lost fingers could be non-invasively generated. However, the encoding of stimulation parameters into tactile sensations that can be intuitively interpreted by the users remains a significant challenge...
2018: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/29759027/upper-limb-congenital-muscular-hypertrophy-and-aberrant-muscle-syndrome-in-children
#12
Emmanuel Dahan, Camilo Chaves, Manon Bachy, Frank Fitoussi
Congenital muscle hypertrophy of the upper limb is a very rare condition with unknown aetiology. This descriptive observational and retrospective series included eight children followed by a multidisciplinary team from 2005 to 2017. The diagnosis was based on a cluster of clinical and radiological characteristics after elimination of differential diagnoses. Patients were categorized according to: anomalies of the wrist, anomalies of long fingers of intrinsic or extrinsic origin; and anomalies of the thumb with or without first web space contracture...
January 1, 2018: Journal of Hand Surgery, European Volume
https://www.readbyqxmd.com/read/29751260/forkhead-box-c1-gene-variant-causing-glaucoma-and-small-vessel-angiopathy-can-mimic-multiple-sclerosis
#13
Jagannadha R Avasarala, Julie R Jones, Curtis R Rogers
A 34-year old Caucasian female was initially diagnosed with multiple small-vessel strokes at age 20 years which were etiologically classified as secondary to anti-phospholipid antibody syndrome (APS) although she had no history or laboratory data to suggest APS. Based on her MRI of brain findings, one of her neurologists was concerned she could have multiple sclerosis (MS) and hence the patient was referred to our clinic for further evaluation. The patient's MRI of brain showed confluent lesions in the periventricular and juxta-cortical lesions that fulfil 2017 McDonald criteria for dissemination in space...
April 21, 2018: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/29750797/critical-depth-raman-spectroscopy-enables-home-use-non-invasive-glucose-monitoring
#14
Signe M Lundsgaard-Nielsen, Anders Pors, Stefan O Banke, Jan E Henriksen, Dietrich K Hepp, Anders Weber
One of the most ambitious endeavors in the field of diabetes technology is non-invasive glucose sensing. In the past decades, a number of different technologies have been assessed, but none of these have found its entry into general clinical use. We report on the development of a table-top confocal Raman spectrometer that was used in the home of patients with diabetes and operated for extended periods of time unsupervised and without recalibration. The system is based on measurement of glucose levels at a 'critical depth' in the skin, specifically in the interstitial fluid located below the stratum corneum but above the underlying adipose tissue layer...
2018: PloS One
https://www.readbyqxmd.com/read/29747624/association-of-wrist-and-forearm-range-of-motion-measures-with-self-reported-functional-scores-amongst-patients-with-distal-radius-fractures-a-longitudinal-study
#15
Zixian Yang, Peggy Poh Hoon Lim, Sing Hwee Teo, Huiwen Chen, Huaying Qiu, Yong Hao Pua
BACKGROUND: Patients with distal radius fractures (DRF) often have limited range-of-motion (ROM) in multiple planes of movement. No studies have comprehensively examined the impact of various ROM limitations on physical function. METHODS: We performed a multi-center, longitudinal study of 138 patients with conservatively managed DRF. ROM measures were taken at initial evaluation, and at 4 and 8 weeks later. Self-reported physical function was indexed by the Quick Disabilities of the Arm, Shoulder and Hand (QuickDASH)...
May 11, 2018: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29745692/hand-preferences-in-two-unimanual-and-two-bimanual-coordinated-tasks-in-the-black-handed-spider-monkey-ateles-geoffroyi
#16
Alba Motes Rodrigo, Carlos Eduardo Ramirez Torres, Laura Teresa Hernandez Salazar, Matthias Laska
Spider monkeys are interesting to study with regard to hand preferences, as they are one of the few primate species that lack a thumb and, thus, are unable to perform a precision grip. Further, being platyrrhine primates, they also largely lack independent motor control of the digits and, thus, have only limited manual dexterity. It was therefore the aim of the present study to assess hand preferences in black-handed spider monkeys ( Ateles geoffroyi ) in 4 tasks differing in task demand: simple unimanual reaching for food and 3 versions of the widely used tube task, including 2 bimanual versions that differ from each other in the degree of fine motor control needed and a unimanual version that does not require coordinated action of the hands...
May 2018: Journal of Comparative Psychology
https://www.readbyqxmd.com/read/29739493/the-treatment-of-primary-arthritis-of-the-finger-and-thumb-joint
#17
Christian Karl Spies, Martin Langer, Peter Hahn, Lars Peter Müller, Frank Unglaub
BACKGROUND: Primary finger and thumb joint arthritis is common, with a markedly rising prevalence from age 50 onward. As the population as a whole ages, the need for effective, stage-appropriate treatment of this condition is increasing. METHODS: This review is based on pertinent publications retrieved by a selective search in the PubMed and Cochrane Library databases. RESULTS: Pain on movement and morning stiffness are commonly reported symptoms...
April 20, 2018: Deutsches Ärzteblatt International
https://www.readbyqxmd.com/read/29736263/using-nerve-transfer-to-restore-prehension-and-grasp-12-years-following-spinal-cord-injury-a-case-report
#18
Ida K Fox, Christine B Novak, Lorna C Kahn, Susan E Mackinnon, Rimma Ruvinskaya, Neringa Juknis
Introduction: Nerve transfers are used routinely for reconstruction of hand function following lower motor neuron lesions. In people with cervical spinal cord injury (SCI), this novel and alternate reconstruction option may be useful to restore prehension and grasp, and improve hand function. Case presentation: A 34-year-old male presented 12 years post-mid-cervical SCI. Pre-operative electrodiagnostic studies revealed intact lower motor neurons below the SCI level...
2018: Spinal Cord Series and Cases
https://www.readbyqxmd.com/read/29735290/incidence-timing-and-risk-factors-for-secondary-revision-after-primary-revision-of-traumatic-digit-amputations
#19
Andrew P Harris, Avi D Goodman, Joseph A Gil, Andrew D Sobel, Neill Y Li, Jeremy E Raducha, Grayson L Baird, Julia A Katarincic
PURPOSE: Primary revision amputation is the most common treatment method for traumatic digit amputations in the United States. Few studies have reported secondary revision rates after primary revision amputation. The primary aim of our study was to identify risk factors for secondary revision within 1 year of the index procedure. Secondarily, we describe the incidence and timing of complications requiring secondary revision. METHODS: Our institution's emergency department (ED) database was reviewed for traumatic digit amputations over a 6-year period...
May 5, 2018: Journal of Hand Surgery
https://www.readbyqxmd.com/read/29734912/pollicisation-the-myth-about-creating-a-pseudo-trapezium
#20
Ulrich Mennen
We have performed 14 pollicisations without creating a "pseudo-trapezium" from the metacarpal head. The entire metacarpal of the intended finger to be pollicised is removed and the proximal phalanx of the finger is inserted into the space left by the base of the excised metacarpal. The results are good to excellent in all 14 cases followed for 2-9 years. The advantages are that the operation is much simpler, thus also much quicker. The new thumb looks more like a thumb (not too long) and is more stable (ball-and-socket joint), with no long term complications often seen with the pseudo-trapezium...
June 2018: Journal of Hand Surgery Asian-Pacific Volume
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