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https://www.readbyqxmd.com/read/28100198/mr-imaging-for-detection-of-trampoline-injuries-in-children
#1
E Hauth, H Jaeger, P Luckey, M Beer
BACKGROUND: The recreational use of trampolines is an increasingly popular activity among children and adolescents. Several studies reported about radiological findings in trampoline related injuries in children. The following publication presents our experience with MRI for detection of trampoline injuries in children. METHODS: 20 children (mean 9.2 years, range: 4-15 years) who had undergone an MRI study for detection of suspected trampoline injuries within one year were included...
January 18, 2017: BMC Pediatrics
https://www.readbyqxmd.com/read/28096444/single-molecule-fret-rosetta-reveals-rna-structural-rearrangements-during-human-telomerase-catalysis
#2
Joseph W Parks, Kalli Kappel, Rhiju Das, Michael D Stone
Maintenance of telomeres by telomerase permits continuous proliferation of rapidly dividing cells, including the majority of human cancers. Despite its direct biomedical significance, the architecture of the human telomerase complex remains unknown. Generating homogeneous telomerase samples has presented a significant barrier to developing improved structural models. Here we pair single-molecule Förster resonance energy transfer (smFRET) measurements with Rosetta modeling to map the conformations of the essential telomerase RNA core domain within the active ribonucleoprotein...
February 2017: RNA
https://www.readbyqxmd.com/read/28095256/evaluation-of-a-psychomotor-vigilance-task-for-touch-screen-devices
#3
Lucia Arsintescu, Jeffrey B Mulligan, Erin E Flynn-Evans
OBJECTIVE: Our goals were to compare three techniques for performing a psychomotor vigilance task (PVT) on a touch screen device (fifth-generation iPod) and to determine the device latency. BACKGROUND: The PVT is a reaction-time test that is sensitive to sleep loss and circadian misalignment. Several PVT tests have been developed for touch screen devices, but unlike the standard PVT developed for laboratory use, these tests allow for touch responses to be recorded at any location on the device, with contact from any finger...
January 1, 2017: Human Factors
https://www.readbyqxmd.com/read/28093922/toll-like-receptors-and-their-soluble-forms-differ-in-the-knee-and-thumb-basal-osteoarthritic-joints
#4
Goncalo Barreto, Jerker Sandelin, Abdelhakim Salem, Dan C Nordström, Eero Waris
Background and purpose - Although the pathogenesis of osteoarthritis (OA) is not well understood, chondrocyte-mediated inflammatory responses (triggered by the activation of innate immune receptors by damage-associated molecules) are thought to be involved. We examined the relationship between Toll-like receptors (TLRs) and OA in cartilage from 2 joints differing in size and mechanical loading: the first carpometacarpal (CMC-I) and the knee. Patients and methods - Samples of human cartilage obtained from OA CMC-I and knee joints were immunostained for TLRs (1-9) and analyzed using histomorphometry and principal component analysis (PCA)...
January 17, 2017: Acta Orthopaedica
https://www.readbyqxmd.com/read/28078364/-ligament-injuries-of-fingers-and-thumbs
#5
R Schmitt
Degenerative and traumatic ligament lesions of the carpometacarpal joints frequently occur at the thumb ray, whereas the carpometacarpal amphiarthrosis of other finger rays are rarely affected. The metacarpophalangeal and interphalangeal joints of the thumb and fingers are stabilized by bilaterally running collateral ligaments and palmar plates. At the base of the metacarpophalangeal joints, several ligaments of the extensor hoods guide the extensor tendons and coordinate the fine motoric skills of phalangeal flexing and extending...
January 2017: Der Radiologe
https://www.readbyqxmd.com/read/28078262/the-leaf-of-diospyros-kaki-thumb-ameliorates-renal-oxidative-damage-in-mice-with-type-2-diabetes
#6
Myung-Sook Choi, Mi Ji Jeong, Yong Bok Park, Sang Ryong Kim, Un Ju Jung
Diabetic kidney disease is the most common and severe chronic complication of diabetes. The leaf of Diospyros kaki Thumb (persimmon) has been commonly used for herbal tea and medicinal purposes to treat a variety of conditions, including hypertension and atherosclerosis. However, the effect of persimmon leaf on kidney failure has not been investigated. This study aimed to examine the role of persimmon leaf in protecting the diabetes-associated kidney damage in a mouse model of type 2 diabetes. Mice were fed either a normal chow diet with or without powered persimmon leaf (5%, w/w) for 5 weeks...
December 2016: Preventive Nutrition and Food Science
https://www.readbyqxmd.com/read/28077485/persistent-anterior-interosseous-nerve-palsy-following-forearm-crutch-use
#7
Peter Macneal, Christopher Robert Crome, Scarlett McNally
A 43-year-old man presented with weakness of the interphalageal joint of his right thumb following the use of forearm crutches. On examination he was unable to oppose his thumb and index finger to form the 'ok' sign. Nerve conduction showed anterior interosseous nerve (AIN) damage along its path to the flexor pollicis longus. The patient was managed conservatively with little clinical improvement seen at 4 months. AIN palsies are very rare and account for <1% of all upper limb lesions. Although AIN palsies resulting from other causes such as surgery and blunt trauma are more common, we report the second case of AIN palsy following crutch use, and the first case in which clinical identification was confirmed using electrodiagnosis...
January 11, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28076751/salter-harris-type-iv-fracture-of-the-proximal-phalanx-of-the-thumb-with-rotation-of-the-epiphysis-outcome-10-years-following-open-reduction-and-k-wire-fixation
#8
Mohammad M Al-Qattan
INTRODUCTION: Salter-Harris type IV fracture of the proximal phalanx with 90° rotation of the epiphysis is very rare. We report on a case of Salter-Harris type IV fracture of the proximal phalanx of the thumb with rotation of the epiphysis and document the outcome 10 years after surgery. PRESENTATION OF CASE: A 5-year old boy presented with Salter-Harris type IV fracture of the thumb with 90° rotation of the epiphysis. Open reduction and K-wire fixation was done...
December 27, 2016: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28075090/carpal-tunnel-syndrome-diagnosis-and-management
#9
Jennifer Wipperman, Kyle Goerl
Carpal tunnel syndrome, the most common entrapment neuropathy of the upper extremity, is caused by compression of the median nerve as it travels through the carpal tunnel. Classically, patients with the condition experience pain and paresthesias in the distribution of the median nerve, which includes the palmar aspect of the thumb, index and middle fingers, and radial half of the ring finger. Additional clues include positive physical examination findings, such as the flick sign, Phalen maneuver, and median nerve compression test...
December 15, 2016: American Family Physician
https://www.readbyqxmd.com/read/28071597/three-dimensional-printing-of-a-microneedle-array-on-personalized-curved-surfaces-for-dual-pronged-treatment-of-trigger-finger
#10
Seng Han Lim, Jian Yao Ng, Lifeng Kang
The hand function of patients who suffer from trigger finger can be impaired by the use of traditional splints. There is also a risk of systemic side effects with oral non-steroidal anti-inflammatory drugs (NSAIDs) used for pain relief. Microneedle-assisted transdermal drug delivery offers an attractive alternative for local delivery of NSAIDs. However, traditional microneedle arrays fabricated on flat surfaces are unable to deliver drugs effectively across the undulating skin surface of affected finger(s)...
January 10, 2017: Biofabrication
https://www.readbyqxmd.com/read/28071198/fracture-of-the-index-metacarpal-after-tightrope-suspension-for-carpometacarpal-instability-of-the-thumb
#11
S Mufty, S J Peters
No abstract text is available yet for this article.
November 2016: Journal of Hand Surgery, European Volume
https://www.readbyqxmd.com/read/28070622/haptic-feedback-attenuates-illusory-bias-in-pantomime-grasping-evidence-for-a-visuo-haptic-calibration
#12
Jillian Chan, Matthew Heath
Relative visual information has been shown to mediate grasping responses directed to an area previously occupied by a target object (i.e., pantomime-grasping) and is an information type functionally distinct from the absolute visual information supporting naturalistic grasping (i.e., grasping a physical target). Pantomime- and naturalistic grasps differ not only in terms of their visual properties, but also because the former lacks physical interaction with a target object (i.e., no-haptic feedback). The absence of haptic feedback may represent a reason why pantomime- and naturalistic grasps differ...
January 9, 2017: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/28067916/self-correcting-mismatches-during-high-fidelity-dna-replication
#13
Rafael Fernandez-Leiro, Julian Conrad, Ji-Chun Yang, Stefan M V Freund, Sjors H W Scheres, Meindert H Lamers
Faithful DNA replication is essential to all forms of life and depends on the action of 3'-5' exonucleases that remove misincorporated nucleotides from the newly synthesized strand. However, how the DNA is transferred from the polymerase to the exonuclease active site is not known. Here we present the cryo-EM structure of the editing mode of the catalytic core of the Escherichia coli replisome, revealing a dramatic distortion of the DNA whereby the polymerase thumb domain acts as a wedge that separates the two DNA strands...
January 9, 2017: Nature Structural & Molecular Biology
https://www.readbyqxmd.com/read/28062434/thumb-and-index-finger-macrodactyly-with-first-carpometacarpal-and-scaphotrapezotrapezoidal-joints-fusion-inevitable-consequence
#14
Karthikeyan P Iyengar, Hosam E Matar, Khushroo Suraliwala
No abstract text is available yet for this article.
January 6, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28062100/the-effects-of-below-elbow-immobilization-on-driving-performance
#15
Evan M Jones, Aaron E Barrow, Nic J Skordas, David P Green, Mickey S Cho
INTRODUCTION: There is limited research to guide physicians and patients in deciding whether it is safe to drive while wearing various forms of upper extremity immobilization. The purpose of this study is to evaluate the effect of below-elbow removable splints and fiberglass casts on automobile driving performance. METHODS: 20 healthy subjects completed 10 runs through a closed, cone-marked driving course while wearing a randomized sequence of four different types of immobilization on each extremity (short arm thumb spica fiberglass cast, short arm fiberglass cast, short arm thumb spica splint, and short arm wrist splint)...
December 28, 2016: Injury
https://www.readbyqxmd.com/read/28056064/marine-reserve-targets-to-sustain-and-rebuild-unregulated-fisheries
#16
Nils C Krueck, Gabby N Ahmadia, Hugh P Possingham, Cynthia Riginos, Eric A Treml, Peter J Mumby
Overfishing threatens the sustainability of coastal marine biodiversity, especially in tropical developing countries. To counter this problem, about 200 governments worldwide have committed to protecting 10%-20% of national coastal marine areas. However, associated impacts on fisheries productivity are unclear and could weaken the food security of hundreds of millions of people who depend on diverse and largely unregulated fishing activities. Here, we present a systematic theoretic analysis of the ability of reserves to rebuild fisheries under such complex conditions, and we identify maximum reserve coverages for biodiversity conservation that do not impair long-term fisheries productivity...
January 2017: PLoS Biology
https://www.readbyqxmd.com/read/28052834/efficacy-of-dorsoradial-capsulodesis-for-trapeziometacarpal-joint-instability-a%C3%A2-cadaver-study
#17
Brian A Chenoweth, Gavin D O'Mahony, Casey Fitzgerald, Julie A Stoner, Daniel L O'Donoghue, Ghazi M Rayan
PURPOSE: To test the biomechanical properties of the dorsoradial capsulodesis procedure. METHODS: Six cadaveric hands were used. After exposing the trapeziometacarpal (TMC) joint, we placed Kirschner wires in the distal radius and thumb metacarpal. The rotation shear test was then performed to test the joint axial laxity, and angular measurements using Kirschner wires as reference points were documented. The dorsoradial (DR) ligament and capsule were released, followed by the intermetacarpal (IM) ligament; angular measurements were obtained...
January 2017: Journal of Hand Surgery
https://www.readbyqxmd.com/read/28052825/a-population-based-study-of-replantation-after-traumatic-thumb-amputation-2007-2012
#18
Elham Mahmoudi, Helen E Huetteman, Kevin C Chung
PURPOSE: The recommended surgical treatment after thumb amputation is replantation. In the United States, fewer than 40% of thumb amputation injuries are replanted, and little is known about factors associated with the probability of replantation. We aimed to investigate recent trends and examine patient and hospital characteristics that are associated with increased probability of attempted thumb replantation. We hypothesized that higher-volume teaching hospitals and level-I trauma centers attempted more replantations...
January 2017: Journal of Hand Surgery
https://www.readbyqxmd.com/read/28050547/radial-head-fracture-associated-with-posterior-interosseous-nerve-injury
#19
Bernardo Barcellos Terra, Tannus Jorge Sassine, Guilherme de Freitas Lima, Leandro Marano Rodrigues, David Victoria Hoffmann Padua, Anderson de Nadai
: Fractures of the radial head and radial neck correspond to 1.7-5.4% of all fractures and approximately 30% may present associated injuries. In the literature, there are few reports of radial head fracture with posterior interosseous nerve injury. This study aimed to report a case of radial head fracture associated with posterior interosseous nerve injury. CASE REPORT: A male patient, aged 42 years, sought medical care after falling from a skateboard. The patient related pain and limitation of movement in the right elbow and difficulty to extend the fingers of the right hand...
November 2016: Revista Brasileira de Ortopedia
https://www.readbyqxmd.com/read/28046626/su-f-t-74-experimental-validation-of-monaco-electron-monte-carlo-dose-calculation-for-small-fields
#20
Varadhan, S Way, L Arentsen, B Gerbi
PURPOSE: To verify experimentally the accuracy of Monaco (Elekta) electron Monte Carlo (eMC) algorithm to calculate small field size depth doses, monitor units and isodose distributions. METHODS: Beam modeling of eMC algorithm was performed for electron energies of 6, 9, 12 15 and 18 Mev for a Elekta Infinity Linac and all available (6, 10, 14 20 and 25 cone) applicator sizes. Electron cutouts of incrementally smaller field sizes (20, 40, 60 and 80% blocked from open cone) were fabricated...
June 2016: Medical Physics
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