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Marta Costa, Gonçalo Ferreira, Dora Gomes, Catarina Oliveira, Nelson Domingues
May-Thurner syndrome (MTS) is caused by compression of the left common iliac vein by the right common iliac artery against the spinal column. It can range from asymptomatic or present with subtle and unspecific signs and symptoms and rarely exhibit severe complications such as pulmonary embolism (PE). The diagnosis is confirmed by typical imaging findings. Treatment may include conservative measures, anticoagulation, endovascular or even surgical options. We report the case of a 20-year-old female who presented with cardiac arrest caused by an acute massive PE...
March 2024: Curēus
#2
JOURNAL ARTICLE
Natsuki Kawabata, Naoki Asakawa
A new technique for ex situ solid-state nuclear magnetic resonance imaging of polymeric films has been developed. This method uses the static magnetic field gradient generated by a water-cooled copper electromagnet. The imaging process involves scanning the sample in the plane of the film under a static magnetic field gradient. Two-dimensional (2D) 19F MRI measurements are attempted, where the fast Fourier transform (FFT) spectra of the second half of a Hahn echo peak is used for the depth (X-axis) direction, and the sample film is mechanically moved for the Y-axis, which is in-plane with respect to the film surface and normal to the inter-magnetic-pole line (Z-axis)...
April 1, 2024: Review of Scientific Instruments
#3
Ali Alsuheel Asseri, Ahmad A Alzoani, Mohammed Almahdi, Hussein Almahdi, Nouf Almushayt, Noha Saad Alyazidi, Basmah Mohammed Al Mufarrih
Jeune syndrome, or asphyxiating thoracic dystrophy (JATD), is a rare autosomal recessive skeletal dysplasia with heterogeneous genetic and clinical phenotypes, which primarily affects cartilage and bone development. Herein, we report a patient with a lethal form of SRTD3 without polydactyly (JATD), which led to severe restrictive lung disease and fatal respiratory failure. A full-term boy was born to a 30-year-old mother who was known to have hypothyroidism and was on thyroxine. The parents were first-degree cousins and had one healthy older son...
2024: International Medical Case Reports Journal
#4
JOURNAL ARTICLE
Benjamin Paik, Nicole Tze-Yan Ngai, Jess Rhee, Kendrick Co Shih, Khyber Alam, Louis Tong
PURPOSE: Traditional direct ophthalmoscopy (TDO) is the oldest method of fundus examination; however, it has fallen out of use due to its technical difficulty and limitations to clinical utility, amidst the advent of potentially better options. A spectrum of new technologies may help in addressing the shortcomings of TDO: simulation mannequins with non-tracked TDO, simulation models with tracked TDO, and smartphone ophthalmoscopy (SFO). METHODOLOGY: A systematic search of PubMed, Embase, and Cochrane databases for all studies evaluating usage of simulation mannequins/models and SFO in ophthalmology education was performed, from inception till April 2023 with no language restriction...
March 27, 2024: Medical Teacher
#5
JOURNAL ARTICLE
Mikolaj Krysa, Katarzyna Susniak, Cai Li Song, Monika Szymanska-Chargot, Artur Zdunek, Izabela S Pieta, Janusz Podleśny, Anna Sroka-Bartnicka, Sergei G Kazarian
Maize ( Zea mays ) is one of the most cultivated plants in the world. Due to the large area, the scale of its production, and the demand to increase the yield, there is a need for new environmentally friendly fertilizers. One group of such candidates is bacteria-produced nodulation (or nod) factors. Limited research has explored the impact of nodulation, factors on maize within field conditions, with most studies restricted to greenhouse settings and early developmental stages. Additionally, there is a scarcity of investigations that elucidate the metabolic alterations in the maize stem due to nod-factor exposure...
March 26, 2024: Applied Spectroscopy
#6
JOURNAL ARTICLE
Michaela Javorkova, Andrea Bystricanova, Martina Cirbusova, Marcela Cvoligova, Martin Chrastina, Juraj Maris, Janka Otavkova, Zuzana Zilinska
Conn's syndrome, defined as unilateral aldosterone-producing adenoma, accounts for 35-40% of cases of primary hyperaldosteronism. Primary hyperaldosteronism typically occurs in younger patients with poorly controlled arterial hypertension due to extracellular fluid retention, in whom at least a triple combination of antihypertensives, including a diuretic, is needed to maintain normotension. The clinical picture of arterial hypertension may be complemented by symptoms associated with hypokalaemia, such as weakness, fatigue, palpitations, convulsions, polydipsia, or polyuria...
2024: Bratislavské Lekárske Listy
#7
JOURNAL ARTICLE
Qiaozhi Yu, Zhengjian Yao, Jiaqi Zhou, Wenhao Yu, Chenjie Zhuang, Yafeng Qi, Hanqing Xiong
Stimulated Raman scattering (SRS) has been developed as an essential quantitative contrast for chemical imaging in recent years. However, while spectral lines near the natural linewidth limit can be routinely achieved by state-of-the-art spontaneous Raman microscopes, spectral broadening is inevitable for current mainstream SRS imaging methods. This is because those SRS signals are all measured in the frequency domain. There is a compromise between sensitivity and spectral resolution: as the nonlinear process benefits from pulsed excitations, the fundamental time-energy uncertainty limits the spectral resolution...
March 8, 2024: Light, Science & Applications
#8
JOURNAL ARTICLE
Chang Zhou, Jie Cao, Qun Hao, Huan Cui, Haifeng Yao, Yaqian Ning, Haoyu Zhang, Moudan Shi
Ghost imaging (GI) has been widely used in the applications including spectral imaging, 3D imaging, and other fields due to its advantages of broad spectrum and anti-interference. Nevertheless, the restricted sampling efficiency of ghost imaging has impeded its extensive application. In this work, we propose a novel foveated pattern affine transformer method based on deep learning for efficient GI. This method enables adaptive selection of the region of interest (ROI) by combining the proposed retina affine transformer (RAT) network with minimal computational and parametric quantities with the foveated speckle pattern...
February 26, 2024: Optics Express
#9
Aditi P Ambekar, Mitushi Deshmukh, Vaishnavi M Thakre, Pooja S Ladkhedkar, Palak R Ahuja
Distal ulna and radius fractures are the most frequent upper extremity fractures seen in emergency rooms. The axis of rotation for forearm pronation and supination runs through the radial head (proximal) and the ulnar fovea (distal). Throughout pronation and supination, the radius can rotate relative to the ulna, thanks to the way its head articulates with it. The ulna remains relatively stable during these movements. However, in cases of fractures of these bones, surgery to repair the radius is usually the best course of action for a distal ulna fracture...
January 2024: Curēus
#10
JOURNAL ARTICLE
Hinako Oshiro, Junichi Hata, Daisuke Nakashima, Rintaro Oshiro, Naoya Hayashi, Yawara Haga, Kei Hagiya, Daisuke Yoshimaru, Hideyuki Okano
In diffusion magnetic resonance imaging, oscillating gradient spin echo (OGSE) has an extremely short diffusion time if motion probing gradient (MPG) is applied to the waveform. Further, it can detect microstructural specificity. OGSE changes sensitivity to spin displacement velocity based on the MPG phase. The current study aimed to investigate the restricted diffusion characteristics of each OGSE waveform using the capillary phantom with various b-values, frequencies, and MPG phases. We performed OGSE (b-value = 300, 500, 800, 1200, 1600, and 2000 s/mm2 ) for the sine and cosine waveforms using the capillary phantom (6, 12, 25, 50, and 100 μm and free water) with a 9...
February 29, 2024: Heliyon
#11
Linjun Cai, Xu Liu, Hongyu Zhou, Jinmei Li, Dong Zhou, Zhen Hong
Neuromyelitis optica spectrum disorder (NMOSD) is a rare demyelinating disease of the central nervous system primarily affecting the optic nerves, spinal cord, and brainstem. Viral infection may trigger NMOSD. Here, we report the case of a 34-year-old female presenting with a range of symptoms including nausea, vomiting, dysphagia, choking, and fatigue with unsteady gait, diplopia, hearing loss, left-sided facial paralysis, breathing difficulties, and hoarseness of voice. Her HBV DNA concentration, as determined by quantitative PCR analysis, exceeded 5×107 IU/ml in serum and 4...
2024: Frontiers in Immunology
#12
JOURNAL ARTICLE
Anna Lisa Martini, Natale Quartuccio, Irene Giovanna Schiera, Valentina Berti, Luca Burroni, Angelina Cistaro
Autism spectrum disorder (ASD) consists of neurological development disorders that manifest before three years of age and affect social interactions, markedly restricting range of interests and activities, often associated with some degree of intellectual disability. Single-photon emission computed tomography (SPECT) and positron emission tomography (PET) are non-invasive imaging tools to investigate the function of the brain in vivo. SPECT and PET studies exploring rCBF and brain glucose metabolism in patients with ASD have been performed, providing important insights into the brain regions involved in ASD...
2024: Current medical imaging
#13
André Rosas Pereira, Marta Costa, Gustavo G Costa, Ana Sofia Carvalho
Anorexia nervosa (AN) belongs to the spectrum of food disorders and affects approximately 2.9 million people worldwide. It is responsible for numerous and serious medical complications. Osteoporosis is a common complication, and the decrease in bone mineral density (BMD) is one of the few potentially irreversible consequences of AN. When associated with AN, it can manifest at a very young age, possibly leading to irreparable damage. We describe the case of a 30-year-old woman with a one-year evolution diagnosis of AN, complaining of back pain...
January 2024: Curēus
#14
JOURNAL ARTICLE
Lindsey Wooliscroft, Amber Salter, Gautam Adusumilli, Victoria A Levasseur, Peng Sun, Samantha Lancia, Dana C Perantie, Kathryn Trinkaus, Robert T Naismith, Sheng-Kwei Song, Anne H Cross
BACKGROUND AND OBJECTIVES: Diffusion basis spectrum imaging (DBSI) extracts multiple anisotropic and isotropic diffusion tensors, providing greater histopathologic specificity than diffusion tensor imaging (DTI). Persistent black holes (PBH) represent areas of severe tissue damage in multiple sclerosis (MS), and a high PBH burden is associated with worse MS disability. This study evaluated the ability of DBSI and DTI to predict which acute contrast-enhancing lesions (CELs) would persist as T1 hypointensities (i...
February 11, 2024: Multiple Sclerosis and related Disorders
#15
Karoline Kallis, Christopher C Conlin, Courtney Ollison, Michael E Hahn, Rebecca Rakow-Penner, Anders M Dale, Tyler M Seibert
BACKGROUND: Restriction Spectrum Imaging restriction score (RSIrs) is a quantitative biomarker for detecting clinically significant prostate cancer (csPCa). However, the quantitative value of the RSIrs is affected by imaging parameters such as echo time (TE). PURPOSE: The purpose of the present study is to develop a calibration method to account for differences in echo times and facilitate use of RSIrs as a quantitative biomarker for the detection of csPCa. METHODS: This study included 197 consecutive patients who underwent MRI and biopsy examination; 97 were diagnosed with csPCa (grade group ≥ 2)...
January 26, 2024: medRxiv
#16
JOURNAL ARTICLE
Amrou Sarraj, Ameer E Hassan, Michael G Abraham, Santiago Ortega-Gutierrez, Scott E Kasner, Muhammad Shazam Hussain, Michael Chen, Leonid Churilov, Hannah Johns, Clark W Sitton, Vignan Yogendrakumar, Felix C Ng, Deep K Pujara, Spiros Blackburn, Sophia Sundararajan, Yin C Hu, Nabeel A Herial, Juan F Arenillas, Jenny P Tsai, Ronald F Budzik, William J Hicks, Osman Kozak, Bernard Yan, Dennis J Cordato, Nathan W Manning, Mark W Parsons, Andrew Cheung, Ricardo A Hanel, Amin N Aghaebrahim, Teddy Y Wu, Pere Cardona Portela, Chirag D Gandhi, Fawaz Al-Mufti, Natalia Pérez de la Ossa, Joanna D Schaafsma, Jordi Blasco, Navdeep Sangha, Steven Warach, Timothy J Kleinig, Faris Shaker, Faisal Al Shaibi, Gabor Toth, Mohammad A Abdulrazzak, Gagan Sharma, Abhishek Ray, Jeffrey Sunshine, Amanda Opaskar, Kelsey R Duncan, Wei Xiong, Edgar A Samaniego, Laith Maali, Colleen G Lechtenberg, Arturo Renú, Nirav Vora, Thanh Nguyen, Johanna T Fifi, Stavropoula I Tjoumakaris, Pascal Jabbour, Georgios Tsivgoulis, Vitor Mendes Pereira, Maarten G Lansberg, Michael DeGeorgia, Cathy A Sila, Nicholas Bambakidis, Michael D Hill, Stephen M Davis, Lawrence Wechsler, James C Grotta, Marc Ribo, Greg W Albers, Bruce C Campbell
IMPORTANCE: Whether endovascular thrombectomy (EVT) efficacy for patients with acute ischemic stroke and large cores varies depending on the extent of ischemic injury is uncertain. OBJECTIVE: To describe the relationship between imaging estimates of irreversibly injured brain (core) and at-risk regions (mismatch) and clinical outcomes and EVT treatment effect. DESIGN, SETTING, AND PARTICIPANTS: An exploratory analysis of the SELECT2 trial, which randomized 352 adults (18-85 years) with acute ischemic stroke due to occlusion of the internal carotid or middle cerebral artery (M1 segment) and large ischemic core to EVT vs medical management (MM), across 31 global centers between October 2019 and September 2022...
March 5, 2024: JAMA
#17
JOURNAL ARTICLE
K A Donald, C J Hendrikse, A Roos, C J Wedderburn, S Subramoney, J E Ringshaw, L Bradford, N Hoffman, T Burd, K L Narr, R P Woods, H J Zar, S H Joshi, D J Stein
Prenatal alcohol exposure (PAE) can affect brain development in early life, but few studies have investigated the effects of PAE on trajectories of white matter tract maturation in young children. Here we used diffusion weighted imaging (DWI) repeated over three time points, to measure the effects of PAE on patterns of white matter microstructural development during the pre-school years. Participants were drawn from the Drakenstein Child Health Study (DCHS), an ongoing birth cohort study conducted in a peri-urban community in the Western Cape, South Africa...
January 28, 2024: NeuroImage: Clinical
#18
JOURNAL ARTICLE
Wei Zhang, Aaron J Gorelik, Qing Wang, Sara A Norton, Tamara Hershey, Arpana Agrawal, Janine D Bijsterbosch, Ryan Bogdan
COVID-19 remains a significant international public health concern. Yet, the mechanisms through which symptomatology emerges remain poorly understood. While SARS-CoV-2 infection may induce prolonged inflammation within the central nervous system, the evidence primarily stems from limited small-scale case investigations. To address this gap, our study capitalized on longitudinal UK Biobank neuroimaging data acquired prior to and following COVID-19 testing (N = 416 including n = 224 COVID-19 cases; Mage = 58...
March 2024: Brain, behavior, & immunity health
#19
JOURNAL ARTICLE
Sebastian M Christ, Kaspar Pohl, Jonas Willmann, Philip Heesen, Astrid Heusel, Maiwand Ahmadsei, Anja Kühnis, Eugenia Vlaskou Badra, Urs J Muehlematter, Michael Mayinger, Panagiotis Balermpas, Nicolaus Andratschke, Nicholas Zaorsky, Martin Huellner, Matthias Guckenberger
INTRODUCTION AND BACKGROUND: Metastatic disease has been proposed as a continuum, with no clear cut-off between oligometastatic and polymetastatic disease. This study aims to quantify tumor burden and patterns of spread in unselected metastatic cancer patients referred for PET-based staging, response assessment of restaging. MATERIALS AND METHODS: All oncological fluorodeoxyglucose (FDG-) and prostate-specific membrane antigen (PSMA-) positron emission tomography (PET) scans conducted at a single academic center in 2020 were analyzed...
March 2024: Clinical and Translational Radiation Oncology
#20
JOURNAL ARTICLE
Shilu Zhang, Huang Zhou, Liang Zhang, Caiqiong Zhu, Xinyi Du, Linjing Wang, Hongyu Chen, Jun Liu
Supramolecular organic frameworks have been widely applied for biological detection and drug delivery. In this study, a supramolecular organic framework (SOF) is constructed through the self-assembly of a highly photosensitive triarylphosphine oxide guest molecule, OTPP-6-Methyl, with cucurbit [8] uril (CB [8]). The formation of the SOF gradually enhances the weak fluorescence of OTPP-6-Methyl owing to the restriction of the molecular folding motion. Although the high positive charge of OTPP-6-Methyl facilitates binding to various negatively charged substances, the SOF system only demonstrated an obvious fluorescence response to LPA, a biomarker of ovarian cancer, via the disassembly of SOF and subsequent binding of OTPP-6-Methyl with LPA...
January 22, 2024: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
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