keyword
https://read.qxmd.com/read/38463103/delayed-surgical-treatment-of-asymptomatic-severe-traumatic-c7-t1-spondylolisthesis-a-rare-case-report-from-syria
#1
Mohammad Ayham Mohsen, Majd Abouassi, Mustafa Albokai, Safwan Alyousef, Ahed Hamed
INTRODUCTION: Spondylolisthesis is described as the displacement of one vertebra over another, leading to spinal instability and potential nerve compression. When this occurs in the cervicothoracic junction, it can result in unique clinical manifestations. High-grade spondylolisthesis caused by trauma in the cervicothoracic junction of the spine usually results in acute spinal cord injury and quadriparesis. However, a few uncommon cases of the same injury reported minimal or no neurological deficits...
March 2024: Annals of Medicine and Surgery
https://read.qxmd.com/read/38456683/quantifying-the-association-between-surgical-spine-approach-and-tracheostomy-timing-after-traumatic-cervical-spinal-cord-injury
#2
JOURNAL ARTICLE
Ahmad Essa, Husain Shakil, Armaan K Malhotra, James P Byrne, Jetan Badhiwala, Eva Y Yuan, Yingshi He, Andrew S Jack, Francois Mathieu, Jefferson R Wilson, Christopher D Witiw
BACKGROUND AND OBJECTIVES: Recent evidence suggests earlier tracheostomy is associated with fewer complications in patients with complete cervical spinal cord injury (SCI). This study aims to evaluate the influence of spine surgical approach on the association between tracheostomy timing and in-hospital adverse events treating patients with complete cervical SCI. METHODS: This retrospective cohort study was performed using Trauma Quality Improvement Program data from 2017 to 2020...
March 8, 2024: Neurosurgery
https://read.qxmd.com/read/38379893/volumetric-modulated-arc-therapy-craniospinal-irradiation-utilizing-a-vertebral-body-sparing-approach-an-alternative-approach-to-improve-access-and-minimize-toxicity
#3
JOURNAL ARTICLE
Haley K Perlow, Jennifer K Matsui, Ashlee Ewing, Catherine Cadieux, Khaled Dibs, Rituraj Upadhyay, Dukagjin M Blakaj, Sasha J Beyer, Evan M Thomas, John C Grecula, Raju R Raval, Joshua D Palmer
INTRODUCTION: Craniospinal irradiation (CSI) is indicated for adult patients diagnosed with leptomeningeal disease (LMD). Proton-based vertebral body sparing (VBS) CSI has been explored with pediatric patients to minimize hematologic toxicity; however, utilization of VBS in an adult population is limited. A recent phase II trial has shown efficacy of proton-based CSI to treat non-small cell lung and breast cancer with LMD. We hypothesize that VBS CSI using volumetric modulated arc therapy (VMAT) could also effectively reduce dose to vertebral bodies and surrounding organs at risk, minimizing toxicity for adult patients with LMD and comparing favorably to proton-based CSI...
March 2024: Advances in Radiation Oncology
https://read.qxmd.com/read/38376554/brain-and-spine-malformations-and-neurodevelopmental-disorders-in-a-cohort-of-children-with-cakut
#4
JOURNAL ARTICLE
Silvia Boeri, Monica Bodria, Rosa Maria Ammendola, Thea Giacomini, Domenico Tortora, Lino Nobili, Michela Malacarne, Andrea Rossi, Enrico Verrina, Giorgio Piaggio, Maria Margherita Mancardi, Mariasavina Severino
BACKGROUND: Congenital anomalies of the kidney and urinary tract (CAKUT) represent 20-30% of all birth defects and are often associated with extra-renal malformations. We investigated the frequency of brain/spine malformations and neurological features in children with CAKUT. METHODS: We reviewed the clinico-radiological and genetic data of 199 out of 1,165 children with CAKUT evaluated from 2006 to 2023 (99 males, mean age at MRI 6.4 years) who underwent brain and/or spine MRI...
February 20, 2024: Pediatric Nephrology
https://read.qxmd.com/read/38262499/getting-what-you-pay-for-impact-of-copayments-on-physical-therapy-and-opioid-initiation-timing-and-continuation-for-newly-diagnosed-low-back-pain
#5
JOURNAL ARTICLE
Michael C Jin, Michael Jensen, Maria Isabel Barros Guinle, Alexander Ren, Zeyi Zhou, Corinna C Zygourakis, Atman M Desai, Anand Veeravagu, John K Ratliff
BACKGROUND CONTEXT: Physical therapy (PT) is an important component of low back pain (LBP) management. Despite established guidelines, heterogeneity in medical management remains common. PURPOSE: We sought to understand how copayments impact timing and utilization of PT in newly diagnosed LBP. STUDY DESIGN/SETTING: The IBM Watson Health MarketScan claims database was utilized in a longitudinal setting. PATIENT SAMPLE: Adult patients with LBP...
January 21, 2024: Spine Journal: Official Journal of the North American Spine Society
https://read.qxmd.com/read/38029387/differentiating-shoulder-pathology-from-cervical-spine-pathology-an-algorithmic-approach
#6
JOURNAL ARTICLE
Christopher M Brusalis, Karan S Patel, Howard S An, Nikhil N Verma
Accurate and timely diagnosis of musculoskeletal conditions is an essential component of high-quality orthopaedic care. The proximity of the shoulder to the cervical spine leads to a multitude of pathologic conditions whose clinical presentations overlap, posing a diagnostic challenge to orthopaedic providers. Missed or delayed diagnosis of the etiology for patient-described 'shoulder pain' causes frustration among patients, incurs increased healthcare costs, and delays treatment. Moreover, patients with concurrent conditions of the cervical spine and shoulder require deliberate consideration for how each condition contributes to patients' symptoms...
November 28, 2023: Journal of the American Academy of Orthopaedic Surgeons
https://read.qxmd.com/read/37980513/understanding-the-management-of-pediatric-spondylodiscitis-based-on-existing-literature-a-systematic-review
#7
JOURNAL ARTICLE
Narges Lashkarbolouk, Mahdi Mazandarani, Brice Ilharreborde, Mohammad Hossein Nabian
BACKGROUND: Spondylodiscitis (SD), a rare disease in children, poses diagnostic challenges due to non-specific presenting symptoms, scarcity in incidence, and difficulty expressing pain in non-verbal children. METHOD: A comprehensive search was conducted on three databases, including PubMed/Medline, Web of Science, and Scopus until March 2023. The inclusion criteria were studies that investigated the clinical characteristics, treatment, and complications of children's spondylodiscitis...
November 18, 2023: BMC Pediatrics
https://read.qxmd.com/read/37971932/imaging-of-vertebral-artery-dissection-in-children-an-underrecognized-condition-with-high-risk-of-recurrent-stroke
#8
JOURNAL ARTICLE
Stephen B Little, Asha Sarma, Manish Bajaj, Sumit Pruthi, Kartik Reddy, Andrew Reisner, Bryan Philbrook, Lori C Jordan
Vertebral artery dissection (VAD) is a common cause of a rare condition, pediatric posterior circulation arterial ischemic stroke (PCAIS). VAD is clinically important due to the risk of multifocal and continuing infarcts from artery-to-artery thromboembolism, with the potential for occlusion of arteries that perfuse the brainstem. Early diagnosis is important, as recurrent stroke is a common effect of VAD in children. Although the relative efficacies of different treatment regimens for VAD in children remain unsettled, early initiation of treatment can mitigate the risk of delayed stroke...
December 2023: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://read.qxmd.com/read/37942814/network-meta-analysis-of-c5-palsy-after-anterior-cervical-decompression-of-3-6-levels-comparing-three-different-procedures
#9
JOURNAL ARTICLE
Hajime Takase, Tatsuya Haze, Daisuke Yamamoto, Naoko Inagaki, Manabu Nitta, Murata Hidetoshi, Tetsuya Yamamoto
STUDY DESIGN: Systematic review and meta-analysis. OBJECTIVE: Using a network meta-analysis, this study aimed to compare the risks of C5 palsy after three different procedures of anterior cervical decompression. SUMMARY OF BACKGROUND DATA: C5 palsy is a well-known complication affecting quality of life after anterior procedures. Due to the limited evidence on the various procedures available, we evaluate the basis for selection to prevent palsy and achieve maximal decompression in cases spanning 3-6 levels...
November 6, 2023: Spine
https://read.qxmd.com/read/37903098/the-value-of-clinical-signs-in-the-diagnosis-of-degenerative-cervical-myelopathy-a-systematic-review-and-meta-analysis
#10
REVIEW
Zhilin Jiang, Benjamin Davies, Carl Zipser, Konstantinos Margetis, Allan Martin, Stavros Matsoukas, Freschta Zipser-Mohammadzada, Najmeh Kheram, Andrea Boraschi, Elina Zakin, Oke Righteous Obadaseraye, Michael G Fehlings, Jamie Wilson, Ratko Yurac, Chad E Cook, Jamie Milligan, Julia Tabrah, Shirley Widdop, Lianne Wood, Elizabeth A Roberts, Tanzil Rujeedawa, Lindsay Tetreault
STUDY DESIGN: Delayed diagnosis of degenerative cervical myelopathy (DCM) is likely due to a combination of its subtle symptoms, incomplete neurological assessments by clinicians and a lack of public and professional awareness. Diagnostic criteria for DCM will likely facilitate earlier referral for definitive management. OBJECTIVES: This systematic review aims to determine (i) the diagnostic accuracy of various clinical signs and (ii) the association between clinical signs and disease severity in DCM? METHODS: A search was performed to identify studies on adult patients that evaluated the diagnostic accuracy of a clinical sign used for diagnosing DCM...
October 30, 2023: Global Spine Journal
https://read.qxmd.com/read/37786328/bone-health-in-satb2-associated-syndrome-results-from-a-large-prospective-cohort-and-recommendations-for-surveillance
#11
JOURNAL ARTICLE
Yuri A Zarate, Katherine Bosanko, Aline Andres, Jennifer L Fish
Alterations in SATB2 result in SATB2-associated syndrome (SAS; Glass syndrome, OMIM 612313), an autosomal dominant multisystemic disorder predominantly characterized by developmental delay, craniofacial anomalies, and growth retardation. The bone phenotype of SAS has been less explored until recently and includes a variety of skeletal deformities, increased risk of low bone mineral density (BMD) with a propensity to fractures, and other biochemical abnormalities that suggest elevated bone turnover. We present the results of ongoing surveillance of bone health from 32 individuals (47% females, 3-18 years) with molecularly-confirmed SAS evaluated at a multidisciplinary clinic...
October 2, 2023: American Journal of Medical Genetics. Part A
https://read.qxmd.com/read/37784434/volumetric-modulated-arc-therapy-craniospinal-irradiation-utilizing-a-vertebral-body-sparing-approach-a-toxicity-analysis
#12
JOURNAL ARTICLE
H K Perlow, J K Matsui, A Ewing, C Cadieux, D M Blakaj, S Beyer, E M Thomas, J C Grecula, R Raval, J D Palmer
PURPOSE/OBJECTIVE(S): Craniospinal irradiation (CSI) is indicated for adult patients diagnosed with leptomeningeal disease (LMD). Proton-based vertebral-body-sparing (VBS) CSI has been explored with pediatric patients to minimize hematologic toxicity; however, utilization of VBS in an adult population is limited. A recent phase II trial (Yang et al, JCO 2022) has shown efficacy of proton-based CSI to treat non-small cell lung and breast cancer with LMD. We hypothesize that VBS-CSI utilizing volumetric modulated arc therapy (VMAT) could also effectively reduce dose to vertebral bodies and surrounding organs-at-risk (OARs), minimizing toxicity for adult patients with LMD and comparing favorably to proton-based CSI...
October 1, 2023: International Journal of Radiation Oncology, Biology, Physics
https://read.qxmd.com/read/37770192/preoperative-dehydration-predicts-adverse-events-following-anterior-cervical-discectomy-and-fusion
#13
JOURNAL ARTICLE
Abdullah Ghali, Gautham Prabhakar, David Momtaz, Farhan Ahmad, Adam Abbas, Muhammad Shamim, Mahmoud Issa, Varun Bora, Christopher Chaput
BACKGROUND: Anterior cervical discectomy and fusion (ACDF) is a common procedure for neck arthritis, typically alleviating pain and improving function. Preoperative dehydration has been correlated with postoperative infection, acute renal failure, deep vein thrombosis, and increased hospital length of stay. However, some studies have suggested that preoperative dehydration has a minimal relationship with postoperative outcomes, specifically in arthroplasty and lumbar surgery candidates...
September 28, 2023: International Journal of Spine Surgery
https://read.qxmd.com/read/37732722/pre-hospital-and-post-hospital-quality-of-care-in-traumatic-spinal-column-and-cord-injuries-in-iran
#14
JOURNAL ARTICLE
Arman Zeinaddini-Meymand, Vali Baigi, Mohammad Mehdi Mousavi-Nasab, Sina Shool, Mohsen Sadeghi-Naini, Zahra Azadmanjir, Seyed Behnam Jazayeri, Samuel Berchi Kankam, Mohammad Dashtkoohi, Aidin Shakeri, Esmail Fakharian, Leila Kouchakinejad-Eramsadati, Habibollah Pirnejad, Homayoun Sadeghi-Bazargani, Laleh Bagheri, Yasaman Pourandish, Malihe Amiri, Ahmad Pour-Rashidi, James Harrop, Vafa Rahimi-Movaghar
STUDY DESIGN: A retrospective study. OBJECTIVES: The quality of care (QoC) for spinal column/cord injury patients is a major health care concern. This study aimed to implement the QoC assessment tool (QoCAT) in the National Spinal Cord/Column Injury Registry of Iran (NSCIR-IR) to define the current state of pre- and post-hospital QoC of individuals with Traumatic Spinal Column and Spinal Cord Injuries (TSC/SCIs). METHODS: The QoCAT, previously developed by our team to measure the QoC in patients with TSC/SCIs, was implemented in the NSCIR-IR...
September 21, 2023: Global Spine Journal
https://read.qxmd.com/read/37728398/neurosurgical-management-of-cervicomedullary-compression-spinal-stenosis-and-hydrocephalus-in-pediatric-achondroplasia-a-systematic-review
#15
JOURNAL ARTICLE
Oluwatoyin Akinnusotu, Albert M Isaacs, Michelle Stone, Christopher M Bonfield
OBJECTIVE: Pediatric achondroplasia is often associated with conditions requiring neurosurgical intervention, including CSF diversion and multilevel spinal decompression. However, there is a lack of clinical guidelines and reliable estimates of the benefits and risks of these interventions. This study aimed to summarize the literature on the neurosurgical management of pediatric achondroplasia patients in order to aid in determining optimal treatment and standardization of care. METHODS: A systematic review of peer-reviewed studies with an objective diagnosis of achondroplasia, patient demographic information, and available data on neurosurgical interventions performed before 18 years of age for cervicomedullary compression, spinal stenosis, and hydrocephalus was performed...
August 18, 2023: Journal of Neurosurgery. Pediatrics
https://read.qxmd.com/read/37667711/partial-recovery-in-toxic-leukoencephalopathy-is-it-really-a-slow-improvement-or-a-warning-sign
#16
Jigar P Mankad, Kyle Paulsen, Mihir Shah
A 55-year-old African American man who was found down by a friend nine hours after being last seen at the same place was brought to the emergency department (ED) with encephalopathy, lactic acidosis, rhabdomyolysis, elevated troponin, acute kidney injury (AKI), and transaminitis. His urine drug screen (UDS) was positive for cocaine. Intravenous (IV) Narcan was given with minimal improvement in mental status. A computed tomography (CT) scan of the head and a CT scan of the cervical spine in the ED showed no acute findings...
August 2023: Curēus
https://read.qxmd.com/read/37663715/surgical-treatment-of-candida-albicans-spondylodiscitis
#17
Prashant Adhikari, Nishma Pokharel, Sulochana Khadka, Ishwar Lohani, Prakash Kafle, Sandeep Bhandari, Bhaskar Raj Pant, Pradeep Raj Regmi, Emre Acaroğlu
INTRODUCTION: Spinal infection poses a demanding diagnostic and treatment problem for which a multidisciplinary approach with spine surgeons, radiologists, and infectious disease specialists is required. Infections are usually caused by bacterial microorganisms, although fungal infections can also occur. Most patients with spinal infections diagnosed in the early stages can be successfully managed conservatively with antibiotics, bed rest, and spinal braces. In cases of gross or pending instability, progressive neurological deficits, failure of conservative treatment, spinal abscess formation, severe symptoms indicating sepsis, and failure of previous conservative treatment, surgical treatment is required...
September 2023: Annals of Medicine and Surgery
https://read.qxmd.com/read/37651573/delayed-diagnosis-of-cervical-epidural-hematoma-in-a-3-year-old-boy-a-case-report
#18
JOURNAL ARTICLE
Yan Zhou, Gina Guglielmi, Sumeet Garg, Todd C Hankinson
CASE: A 3-year-old boy presented to the emergency department with torticollis after a fall. With normal cervical radiographs and neurologic exam, he was diagnosed with cervical strain and discharged. After 2-week progressive symptoms, he was referred to a pediatric spine surgeon. Magnetic resonance imaging (MRI) revealed a cervical epidural hematoma, which was then surgically evacuated. He recovered fully and remains symptom-free 2 years later. CONCLUSION: Pediatric spinal epidural hematoma is a rare condition with potentially serious outcomes yet often nonspecific symptoms...
July 1, 2023: JBJS Case Connector
https://read.qxmd.com/read/37586838/deep-phenotyping-of-the-neuroimaging-and-skeletal-features-in-kbg-syndrome-a-study-of-53-patients-and-review-of-the-literature
#19
JOURNAL ARTICLE
Francesca Peluso, Stefano G Caraffi, Gianluca Contrò, Lara Valeri, Manuela Napoli, Giorgia Carboni, Alka Seth, Roberta Zuntini, Emanuele Coccia, Guja Astrea, Anne-Marie Bisgaard, Ivan Ivanovski, Silvia Maitz, Elise Brischoux-Boucher, Melissa T Carter, Maria Lisa Dentici, Koenraad Devriendt, Melissa Bellini, Maria Cristina Digilio, Asif Doja, David A Dyment, Stense Farholt, Carlos R Ferreira, Lynne A Wolfe, William A Gahl, Maria Gnazzo, Himanshu Goel, Sabine Weller Grønborg, Trine Hammer, Lorenzo Iughetti, Tjitske Kleefstra, David A Koolen, Francesca Romana Lepri, Gabrielle Lemire, Pedro Louro, Gary McCullagh, Simona F Madeo, Annarita Milone, Roberta Milone, Jens Erik Klint Nielsen, Antonio Novelli, Charlotte W Ockeloen, Rosario Pascarella, Tommaso Pippucci, Ivana Ricca, Stephen P Robertson, Sarah Sawyer, Marie Falkenberg Smeland, Sander Stegmann, Constanze T Stumpel, Amy Goel, Juliet M Taylor, Domenico Barbuti, Annarosa Soresina, Maria Francesca Bedeschi, Roberta Battini, Anna Cavalli, Carlo Fusco, Maria Iascone, Lionel Van Maldergem, Sunita Venkateswaran, Orsetta Zuffardi, Samantha Vergano, Livia Garavelli, Allan Bayat
BACKGROUND: KBG syndrome is caused by haploinsufficiency of ANKRD11 and is characterised by macrodontia of upper central incisors, distinctive facial features, short stature, skeletal anomalies, developmental delay, brain malformations and seizures. The central nervous system (CNS) and skeletal features remain poorly defined. METHODS: CNS and/or skeletal imaging were collected from molecularly confirmed individuals with KBG syndrome through an international network...
August 16, 2023: Journal of Medical Genetics
https://read.qxmd.com/read/37384536/prevalence-of%C3%A2-neck-pain-in%C3%A2-soldiers-as-a-result-of%C3%A2-mild-traumatic-brain-injury-associated-trauma
#20
JOURNAL ARTICLE
Tara Caberwal, Amy S Cecchini, Laurel M Wentz, Cristóbal S Berry-Cabán
INTRODUCTION: Many of the injury mechanisms that cause mild traumatic brain injury (mTBI) also create forces commonly associated with whiplash, resulting in cervical pain injury. The prevalence of associated neck pain with mTBI is not well established. There is a strong indication that injury to the cervical spine may aggravate, cause, and/or impact recovery of symptoms and impairments associated with the concussive event and its primary effect on the brain. The purpose of this study is to help identify the prevalence of ensuing cervical pain within 90 days of a previously documented mTBI and to examine the role of neck pain during concurrent concussive symptoms, in a military population stationed at a large military installation...
January 23, 2024: Military Medicine
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