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nutrition* AND lung cancer

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https://www.readbyqxmd.com/read/27918868/handgrip-dynamometry-and-patient-generated-subjective-global-assessment-in-patients-with-nonresectable-lung-cancer
#1
Ana T Barata, Carla Santos, Marília Cravo, Maria do Céu Vinhas, Catarina Morais, Elisabete Carolino, Lino Mendes, Jorge Roldão Vieira, Jorge Fonseca
INTRODUCTION: Undernutrition is frequently associated with advanced lung cancer. Accurate nutritional assessment tools are important to provide the proper nutritional therapy. Handgrip dynamometry has already been used in these patients, and the findings suggest that it is a good indicator of nutritional status. AIMS: The aim of this study was to evaluate the association between nutritional status and handgrip strength (HGS) in patients with nonresectable lung cancer...
December 5, 2016: Nutrition and Cancer
https://www.readbyqxmd.com/read/27917414/receptivity-and-preferences-for-lifestyle-programs-to-reduce-cancer-risk-among-lung-cancer-family-members
#2
Lisa A Howell, Tabetha A Brockman, Pamela S Sinicrope, Christi A Patten, Paul A Decker, Allan Busta, Shawn Stoddard, Sheila R McNallan, Ping Yang
BACKGROUND: Lifestyle factors and genetic information has been found to contribute to the occurrence of lung cancer. This study assessed receptivity to participating in lifestyle programs to reduce cancer risk among unaffected lung cancer family members. We also explored demographic, medical, and psychosocial correlates of willingness to participate in lifestyle programs. METHODS: Family members who are part of a lung Cancer Family Registry were asked to fill out a survey assessing their receptivity to cancer risk reduction programs including preferences for an individual or family-based program...
September 2016: Adv Cancer Prev
https://www.readbyqxmd.com/read/27897393/cancer-anorexia-hypothalamic-activity-and-its-association-with-inflammation-and-appetite-regulating-peptides-in-lung-cancer
#3
Alessio Molfino, Alessandro Iannace, Maria Chiara Colaiacomo, Alessio Farcomeni, Alessandra Emiliani, Gianfranco Gualdi, Alessandro Laviano, Filippo Rossi Fanelli
BACKGROUND: Energy homeostasis is mediated by the hypothalamus, whose inflammation-induced functional derangements contribute to the onset of anorexia in cancer. By using functional magnetic resonance imaging (fMRI), we determined the patterns of hypothalamic activation after oral intake in anorexic (A), non-anorexic (NA) cancer patients, and in controls (C). METHODS: Lung cancer patients were considered. Hypothalamic activation was recorded in A and NA patients and in C by fMRI, before (T0), immediately after (T1) the administration of an oral nutritional supplement, and after 15 min (T2)...
October 5, 2016: Journal of Cachexia, Sarcopenia and Muscle
https://www.readbyqxmd.com/read/27882862/milk-and-dairy-products-good-or-bad-for-human-health-an-assessment-of-the-totality-of-scientific-evidence
#4
REVIEW
Tanja Kongerslev Thorning, Anne Raben, Tine Tholstrup, Sabita S Soedamah-Muthu, Ian Givens, Arne Astrup
BACKGROUND: There is scepticism about health effects of dairy products in the public, which is reflected in an increasing intake of plant-based drinks, for example, from soy, rice, almond, or oat. OBJECTIVE: This review aimed to assess the scientific evidence mainly from meta-analyses of observational studies and randomised controlled trials, on dairy intake and risk of obesity, type 2 diabetes, cardiovascular disease, osteoporosis, cancer, and all-cause mortality...
2016: Food & Nutrition Research
https://www.readbyqxmd.com/read/27793524/use-of-routinely-available-clinical-nutritional-and-functional-criteria-to-classify-cachexia-in-advanced-cancer-patients
#5
Antonio A L Vigano, José A Morais, Lorella Ciutto, Leonard Rosenthall, Jonathan di Tomasso, Sarah Khan, Henry Olders, Manuel Borod, Robert D Kilgour
BACKGROUND: Cachexia is a highly prevalent syndrome in cancer and chronic diseases. However, due to the heterogeneous features of cancer cachexia, its identification and classification challenge clinical practitioners. OBJECTIVE: To determine the clinical relevance of a cancer cachexia classification system in advanced cancer patients. DESIGN: Beginning with the four-stage classification system proposed for cachexia [non-cachexia (NCa), pre-cachexia (PCa), cachexia (Ca) and refractory cachexia (RCa)], we assigned patients to these cachexia stages according to five classification criteria available in clinical practice: 1) biochemistry (high C-reactive protein or leukocytes, or hypoalbuminemia, or anemia), 2) food intake (normal/decreased), weight loss: 3) moderate (≤5%) or 4) significant (>5%/past six months) and 5) performance status (Eastern Cooperative Oncology Group Performance Status ≥ 3)...
September 20, 2016: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/27788658/malnutrition-in-patients-with-lung-cancer
#6
(no author information available yet)
Many patients with lung cancer have multiple disease-related symptoms that, along with the effect of treatment and the psychological distress of diagnosis, tend to affect their nutrition and quality of life.
October 28, 2016: Nursing Older People
https://www.readbyqxmd.com/read/27787169/nutritional-care-pathway-for-cancer-patients
#7
(no author information available yet)
Malnutrition is common in patients with cancer and a major cause of morbidity and mortality, so how best can nurses identify and manage it in patients with lung cancer?
October 26, 2016: Nursing Standard
https://www.readbyqxmd.com/read/27724106/managing-malnutrition-in-lung-cancer-patients
#8
(no author information available yet)
'By following the lung cancer nutritional care pathway, nurses can optimise and maintain the nutritional status of patients with lung cancer'.
October 6, 2016: Emergency Nurse: the Journal of the RCN Accident and Emergency Nursing Association
https://www.readbyqxmd.com/read/27698539/energy-metabolism-and-nutritional-status-in-hospitalized-patients-with-lung-cancer
#9
Yumi Takemura, Masaya Sasaki, Kenichi Goto, Azusa Takaoka, Akiko Ohi, Mika Kurihara, Naoko Nakanishi, Yasutaka Nakano, Jun Hanaoka
This study aimed to investigate the energy metabolism of patients with lung cancer and the relationship between energy metabolism and proinflammatory cytokines. Twenty-eight patients with lung cancer and 18 healthy controls were enrolled in this study. The nutritional status upon admission was analyzed using nutritional screening tools and laboratory tests. The resting energy expenditure and respiratory quotient were measured using indirect calorimetry, and the predicted resting energy expenditure was calculated using the Harris-Benedict equation...
September 2016: Journal of Clinical Biochemistry and Nutrition
https://www.readbyqxmd.com/read/27635765/practical-multimodal-care-for-cancer-cachexia
#10
Matthew Maddocks, Jane Hopkinson, John Conibear, Annie Reeves, Clare Shaw, Ken C H Fearon
PURPOSE OF REVIEW: Cancer cachexia is common and reduces function, treatment tolerability and quality of life. Given its multifaceted pathophysiology a multimodal approach to cachexia management is advocated for, but can be difficult to realise in practice. We use a case-based approach to highlight practical approaches to the multimodal management of cachexia for patients across the cancer trajectory. RECENT FINDINGS: Four cases with lung cancer spanning surgical resection, radical chemoradiotherapy, palliative chemotherapy and no anticancer treatment are presented...
December 2016: Current Opinion in Supportive and Palliative Care
https://www.readbyqxmd.com/read/27604903/association-of-serum-cotinine-levels-and-lung-cancer-mortality-in-non-smokers
#11
Raja M Flores, Bian Liu, Emanuela Taioli
This study was performed to quantify the association between mortality and known and unknown secondhand smoke (SHS) exposure as measured by cotinine levels in non-smokers. Data collected from 1999 to 2010 in the National Health and Nutrition Examination Survey (NHANES) were linked to the National Death Index. Self-reported non-smokers aged ≥20 years (N = 20 175) were studied. Serum cotinine was measured at recruitment; non-smokers were those with cotinine below the reported race-specific cut-off points (5...
September 7, 2016: Carcinogenesis
https://www.readbyqxmd.com/read/27579534/methionine-deprivation-suppresses-triple-negative-breast-cancer-metastasis-in-vitro-and-in-vivo
#12
Hyein Jeon, Jae Hwan Kim, Eunjung Lee, Young Jin Jang, Joe Eun Son, Jung Yeon Kwon, Tae-Gyu Lim, Sunghoon Kim, Jung Han Yoon Park, Jong-Eun Kim, Ki Won Lee
Nutrient deprivation strategies have been proposed as an adjuvant therapy for cancer cells due to their increased metabolic demand. We examined the specific inhibitory effects of amino acid deprivation on the metastatic phenotypes of the human triple-negative breast cancer (TNBC) cell lines MDA-MB-231 and Hs 578T, as well as the orthotopic 4T1 mouse TNBC tumor model. Among the 10 essential amino acids tested, methionine deprivation elicited the strongest inhibitory effects on the migration and invasion of these cancer cells...
August 25, 2016: Oncotarget
https://www.readbyqxmd.com/read/27578770/extracellular-atp-a-new-player-in-cancer-metabolism-nsclc-cells-internalize-atp-in-vitro-and-in-vivo-using-multiple-endocytic-mechanisms
#13
Yanrong Qian, Xuan Wang, Yunsheng Li, Yanyang Cao, Xiaozhuo Chen
: Intratumoral extracellular ATP concentrations are 100-times higher than those in normal tissues of the same cell origin. However, whether or not cancer cells use the abundant extracellular ATP was unknown until we recently reported that cancer cells internalize ATP. The internalized ATP was found to substantially increase intracellular ATP concentration and promote cell proliferation and drug resistance in cancer cells. Here, using a non-hydrolyzable fluorescent ATP (NHF-ATP), radioactive and regular ATP, coupled with high and low molecular weight dextrans as endocytosis tracers and fluorescence microscopy and ATP assays; cultured human NSCLC A549 and H1299 cells as well as A549 tumor xenografts were found to internalize extracellular ATP at concentrations within the reported intratumoral extracellular ATP concentration range...
August 30, 2016: Molecular Cancer Research: MCR
https://www.readbyqxmd.com/read/27573920/growth-and-nutrition-in-children-with-ataxia-telangiectasia
#14
Emma Stewart, Andrew P Prayle, Alison Tooke, Sara Pasalodos, Mohnish Suri, Andy Bush, Jayesh M Bhatt
BACKGROUND: Ataxia telangiectasia (A-T) is a rare multisystem disease with high early mortality from lung disease and cancer. Nutritional failure adversely impacts outcomes in many respiratory diseases. Several factors influence nutrition in children with A-T. We hypothesised that children with A-T have progressive growth failure and that early gastrostomy tube feeding (percutaneous endoscopic gastrostomy, PEG) is a favourable management option with good nutritional outcomes. METHODS: Data were collected prospectively on weight, height and body mass index (BMI) at the national paediatric A-T clinic...
August 29, 2016: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/27565917/quality-of-life-symptom-status-and-physical-performance-in-patients-with-advanced-non-small-cell-lung-cancer-undergoing-chemotherapy-an-exploratory-analysis-of-secondary-data
#15
Shirin M Shallwani, Maureen J Simmonds, Goulnar Kasymjanova, Jadranka Spahija
OBJECTIVES: Our objectives were: (a) to identify predictors of change in health-related quality of life (HRQOL) in patients with advanced non-small cell lung cancer (NSCLC) undergoing chemotherapy; and (b) to characterize symptom status, nutritional status, physical performance and HRQOL in this population and to estimate the extent to which these variables change following two cycles of chemotherapy. METHODS: A secondary analysis of a longitudinal observational study of 47 patients (24 men and 23 women) with newly diagnosed advanced NSCLC receiving two cycles of first-line chemotherapy was performed...
September 2016: Lung Cancer: Journal of the International Association for the Study of Lung Cancer
https://www.readbyqxmd.com/read/27552101/detailed-dietary-assessment-in-patients-with-inoperable-tumors-potential-deficits-for-nutrition-care-plans
#16
Nikoletta Vidra, Meropi D Kontogianni, Evaggelia Schina, Ioannis Gioulbasanis
Advanced cancer often results in reduced dietary intake; however, data on actual intake at the time of diagnosis are limited. In the present study, a detailed dietary intake assessment was performed in patients with metastatic lung and upper gastrointestinal cancer, before initiation of systemic therapy. Basic demographics and performance status (PS) were recorded. Nutritional status was evaluated through anthropometry, Mini Nutritional Assessment (MNA), and 3 nonconsecutive 24-hour dietary recalls. Of the 84 patients enrolled, 61...
October 2016: Nutrition and Cancer
https://www.readbyqxmd.com/read/27535399/multidisciplinary-care
#17
Megan E Daly, Jonathan W Riess
Optimal multidisciplinary care of the lung cancer patient at all stages should encompass integration of the key relevant medical specialties, including not only medical, surgical, and radiation oncology, but also pulmonology, interventional and diagnostic radiology, pathology, palliative care, and supportive services such as physical therapy, case management, smoking cessation, and nutrition. Multidisciplinary management starts at staging and tissue diagnosis with pathologic and molecular phenotyping, extends through selection of a treatment modality or modalities, management of treatment and cancer-related symptoms, and to survivorship and end-of-life care...
2016: Cancer Treatment and Research
https://www.readbyqxmd.com/read/27496114/predictors-of-in-hospital-mortality-in-patients-with-metastatic-cancer-receiving-specific-critical-care-therapies
#18
Kah Poh Loh, Ankit Kansagra, Meng-Shiou Shieh, Penelope Pekow, Peter Lindenauer, Mihaela Stefan, Tara Lagu
BACKGROUND: In-hospital mortality is high for critically ill patients with metastatic cancer. To help patients, families, and clinicians make an informed decision about invasive medical treatments, we examined predictors of in-hospital mortality among patients with metastatic cancer who received critical care therapies (CCTs). PATIENTS AND METHODS: We used the 2010 California Healthcare Cost and Utilization Project: State Inpatient Databases to identify admissions of patients with metastatic cancer (age ≥18 years) who received CCTs, including invasive mechanical ventilation (IMV), tracheostomy, percutaneous endoscopic gastrostomy (PEG) tube, acute use of dialysis, and total parenteral nutrition (TPN)...
August 2016: Journal of the National Comprehensive Cancer Network: JNCCN
https://www.readbyqxmd.com/read/27493875/salidroside-alleviates-cachexia-symptoms-in-mouse-models-of-cancer-cachexia-via-activating-mtor-signalling
#19
Xiangzheng Chen, Yangping Wu, Tinghan Yang, Mingtian Wei, Yuxi Wang, Xiangbing Deng, Congcong Shen, Wenting Li, Hang Zhang, Weiyong Xu, Lantu Gou, Yong Zeng, Yonghui Zhang, Ziqiang Wang, Jinliang Yang
BACKGROUND: Cachexia has a devastating impact on survival and quality of life for many cancer patients and contributes to nearly one-third of all cancer deaths; also, it is associated with poor responses to chemotherapy and survival. A better understanding of the underlying mechanisms of cancer-associated cachexia (CAC), coupled with effective therapeutic approaches, will improve management of progressive functional impairment in cancer patients. Salidroside, a phenylpropanoid glycoside in Rhodiola rosea L, has been reported to possess potential anti-fatigue, anti-ageing, and anti-Alzheimer's disease properties...
May 2016: Journal of Cachexia, Sarcopenia and Muscle
https://www.readbyqxmd.com/read/27468342/risk-of-cardiovascular-disease-using-framingham-risk-score-in-korean-cancer-survivors
#20
Ji-Hyun So, Jung-Kwon Lee, Jin-Young Shin, Wan Park
BACKGROUND: Cardiovascular disease is an important cause of morbidity and mortality in cancer survivors. The aim of this study was to investigate the modifiable cardiovascular disease risk factors and 10-year probability of the disease based on the Framingham risk score in cancer survivors, compared with the general population. METHODS: A total of 1,225 cancer survivors and 5,196 non-cancer controls who participated in the 2007-2013 Korea National Health and Nutrition Examination Surveys were enrolled...
July 2016: Korean Journal of Family Medicine
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