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https://www.readbyqxmd.com/read/28230009/effect-of-heat-sink-on-the-recurrence-of-small-malignant-hepatic-tumors-after-radiofrequency-ablation
#1
Zheng-Yu Lin, Guo-Lin Li, Jin Chen, Zhong-Wu Chen, Yi-Ping Chen, Sun-Zhi Lin
AIMS: The aim of this study was to investigate the effect of heat sink on the recurrence of hepatic malignant tumors <3 cm after percutaneous radiofrequency ablation (RFA). SUBJECTS AND METHODS: This study included 564 hepatic malignant tumors <3 cm in 381 patients. Preoperative images were used to determine whether these tumors were adjacent to vessels, and the diameter of adjacent vessels was measured. RFA was performed computed tomography (CT), magnetic resonance imaging (MRI) and ultrasound (US) guidance, and postoperative imaging follow-up was then conducted...
December 2016: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/28227389/a-method-to-project-clinical-outcome-topographies-onto-preoperative-mri-to-guide-direct-dbs-targeting
#2
Mahesh B Shenai, Barton L Guthrie, Mahesh B Shenai, Barton L Guthrie, Barton L Guthrie, Mahesh B Shenai
The use of intraoperative MR and direct DBS targeting, relies on anatomical rather than functional data. Historical clinical outcome databases that have recorded stimulation location and magnitude of effect, can provide a useful adjunct in DBS targeting strategies. We present a method for generating clinical outcome topographies, and merging regions of effect onto a pre-operative MR, for surgical planning. The clinical outcome topographies are consistent with more intuitive strategies used by neurosurgeons...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226729/passive-artifact-behavior-prediction-of-interventional-tools-in-high-field-mri-using-a-0-55t-portable-benchtop-mr-scanner
#3
H Abadi, J Krug, A Illanes, M Friebe, H Abadi, J Krug, A Illanes, M Friebe, J Krug, M Friebe, A Illanes, H Abadi
Using magnetic resonance imaging (MRI) for guiding minimally invasive interventions requires surgical devices which on one hand are visible in the MR image but on the other hand do not generate large artifacts, which distort the overall imaging process. Passive markers are one way to visualize devices such as catheters or biopsy needles in MRI. The evaluation of newly developed passive markers usually requires access to high-field MRI scanners (1.5 T and 3 T). This makes the practical evaluation time-consuming and expensive...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28225581/effect-of-sonication-duration-and-power-on-ablation-depth-during-mr-guided-focused-ultrasound-of-bone
#4
Matthew D Bucknor, Eugene Ozhinsky, Rutwik Shah, Roland Krug, Viola Rieke
PURPOSE: To evaluate the effect of differences in sonication duration and power on the size of postcontrast ablation zone following magnetic resonance-guided focused ultrasound (MRgFUS) of bone in a swine femoral bone model. MATERIALS AND METHODS: Experimental procedures received approval from the Institutional Committee on Animal Research. MRgFUS was used to create two thermal lesions in the left femur of six pigs. Each target was subjected to six sonications. 400J of energy was used for each sonication...
February 22, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28217678/usefulness-of-modified-brb-technique-in-treatment-to-ablate-uterine-fibroids-with-magnetic-resonance-image-guided-high-intensity-focused-ultrasound
#5
Jae-Heok Jeong, Kil-Pyo Hong, Yu-Ri Kim, Jae-Eun Ha, Kyu-Sup Lee
OBJECTIVE: If bowels and other structures are in the pathway of high-intensity focused ultrasound (HIFU) beam during magnetic resonance image-guided HIFU (MRgFUS) therapy, filling to the bladder and the rectum and then emptying the bladder (i.e., the BRB technique) is used to avoid them. A modified BRB technique might be useful method to using a uterine elevator method or by inducing uterus downward traction to lower the position of the uterus. METHODS: A total of 156 patients who had undergone MRgFUS surgery treatment for uterine fibroids from March 2015 to February 2016 were included in this retrospective study...
January 2017: Obstetrics & Gynecology Science
https://www.readbyqxmd.com/read/28211622/mri-guided-focused-ultrasound-robotic-system-for-animal-experiments
#6
Marinos Yiannakou, Georgios Menikou, Christos Yiallouras, Cleanthis Ioannides, Christakis Damianou
BACKGROUND: In this paper an MRI-guided focused ultrasound (MRgFUS) robotic system was developed that can be used for conducting experiments in small animals.The target for this robotic system regarding motion was to move a therapeutic ultrasound transducer in two Cartesian axes. METHODS: A single element spherically focused transducer of 3 cm diameter, focusing at 7 cm and operating at 0.4 MHz was used. The positioning device incorporates only MRI compatible materials...
February 17, 2017: International Journal of Medical Robotics + Computer Assisted Surgery: MRCAS
https://www.readbyqxmd.com/read/28210800/preservation-of-the-endometrial-enhancement-after-magnetic-resonance-imaging-guided-high-intensity-focused-ultrasound-ablation-of-submucosal-uterine-fibroids
#7
Young-Sun Kim, Tae-Joong Kim, Hyo Keun Lim, Hyunchul Rhim, Sin-Ho Jung, Joong Hyun Ahn, Jeong-Won Lee, Byoung-Gie Kim
OBJECTIVE: To evaluate the integrity of endometrial enhancement after magnetic resonance imaging-guided high-intensity focused ultrasound (MR-HIFU) ablation of submucosal uterine fibroids based on contrast-enhanced MRI findings, and to identify the risk factors for endometrial impairment. METHODS: In total, 117 submucosal fibroids (diameter: 5.9 ± 3.0 cm) in 101 women (age: 43.6 ± 4.4 years) treated with MR-HIFU ablation were retrospectively analysed...
February 16, 2017: European Radiology
https://www.readbyqxmd.com/read/28194274/moderate-to-deep-sedation-technique-using-propofol-and-ketamine-allowing-synchronised-breathing-for-magnetic-resonance-high-intensity-focused-ultrasound-mr-hifu-treatment-for-uterine-fibroids-a-pilot-study
#8
Hermanus H B Vaessen, F M Knuttel, J M M van Breugel, M E Ikink, J M Dieleman, M A A J van den Bosch, J T A Knape
BACKGROUND: Magnetic resonance high-intensity focused ultrasound (MR-HIFU) treatment for uterine fibroids is rapidly gaining popularity as a treatment modality. This procedure is generally uncomfortable, painful, and requires minimal or absence of movement and an MR-HIFU synchronised breathing pattern of the patient. Procedural sedation and analgesia protocols have become the standard practice in interventional radiology departments worldwide. The aim of this study was to explore if a sedation regimen with low-dose propofol and ketamine performed by trained non-medical sedation practitioners could result in relief of discomfort for the patient and in adequate working conditions for MR-HIFU treatment for uterine fibroids...
2017: Journal of Therapeutic Ultrasound
https://www.readbyqxmd.com/read/28177548/7t-guided-super-resolution-of-3t-mri
#9
Khosro Bahrami, Feng Shi, Islem Rekik, Yaozong Gao, Dinggang Shen
PURPOSE: High-resolution MR images can depict rich details of brain anatomical structures and show subtle changes in longitudinal data. 7T MRI scanners can acquire MR images with higher resolution and better tissue contrast than the routine 3T MRI scanners. However, 7T MRI scanners are currently more expensive and less available in clinical and research centers. To this end, we propose a method to generate super-resolution 3T MRI that resembles 7T MRI, which is called as 7T-like MR image in this paper...
February 8, 2017: Medical Physics
https://www.readbyqxmd.com/read/28177224/protein-stabilized-gadolinium-oxide-gold-nanoclusters-hybrid-for-multimodal-imaging-and-drug-delivery
#10
Lu Han, Jun-Mei Xia, Xin Hai, Yang Shu, Xu-Wei Chen, Jian-Hua Wang
A protein-stabilized multifunctional theranostic nanoplatform, gadolinium oxide-gold nanoclusters hybrid (Gd2O3-AuNCs), is constructed for multimodal imaging and drug delivery. The Gd2O3-AuNCs nanohybrid is developed by integrating Gd2O3 nanocrystals and gold nanoclusters into bovine serum albumin scaffold as a stabilizer. The nanohybrid exhibits favorable biocompatibility and is capable of enhancing the contrast in magnetic resonance and X-ray computed tomography imaging. Meanwhile, the integrated AuNCs component not only endows the nanohybrid to produce red fluorescence, but also sensitizes the generation of singlet oxygen ((1)O2) upon near-infrared laser stimulation at 808 nm...
February 17, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28168682/a-magnetic-resonance-image-guided-breast-needle-intervention-robot-system-overview-and-design-considerations
#11
Samuel Byeongjun Park, Jung-Gun Kim, Ki-Woong Lim, Chae-Hyun Yoon, Dong-Jun Kim, Han-Sung Kang, Yung-Ho Jo
PURPOSE: We developed an image-guided intervention robot system that can be operated in a magnetic resonance (MR) imaging gantry. The system incorporates a bendable needle intervention robot for breast cancer patients that overcomes the space limitations of the MR gantry. METHODS: Most breast coil designs for breast MR imaging have side openings to allow manual localization. However, for many intervention procedures, the patient must be removed from the gantry. A robotic manipulation system with integrated image guidance software was developed...
February 6, 2017: International Journal of Computer Assisted Radiology and Surgery
https://www.readbyqxmd.com/read/28160096/hybrid-approach-for-biliary-interventions-employing-mri-guided-bile-duct-puncture-with-near-real-time-imaging
#12
Christian Wybranski, Maciej Pech, Anke Lux, Jens Ricke, Frank Fischbach, Katharina Fischbach
OBJECTIVE: To assess the feasibility of a hybrid approach employing MRI-guided bile duct (BD) puncture for subsequent fluoroscopy-guided biliary interventions in patients with non-dilated (≤3 mm) or dilated BD (≥3 mm) but unfavorable conditions for ultrasonography (US)-guided BD puncture. METHODS: A total of 23 hybrid interventions were performed in 21 patients. Visualization of BD and puncture needles (PN) in the interventional MR images was rated on a 5-point Likert scale by two radiologists...
February 3, 2017: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/28155952/cuco2s4-nanocrystals-a-new-platform-for-multimodal-imaging-guided-photothermal-therapy
#13
Xiaojuan Huang, Guoying Deng, Lijun Liao, Wenlong Zhang, Guoqiang Guan, Feng Zhou, Zhiyin Xiao, Rujia Zou, Qian Wang, Junqing Hu
Multifunctional nanomaterials open an avenue for the integration of cancer treatment and diagnosis, trending towards the clinical application of nanomedicines in future. Herein, we synthesized biocompatible CuCo2S4 nanocrystals (NCs) via a simple reflux method and unitized them as a new theranostic platform, where an intense near-infrared (NIR) absorption offers the CuCo2S4 NCs a perfect photothermal performance and photoacoustic (PA) imaging ability; the magnetic characteristic of Co allows them to serve as an enhanced magnetic resonance (MR) contrast agent...
February 3, 2017: Nanoscale
https://www.readbyqxmd.com/read/28149968/7t-guided-learning-framework-for-improving-the-segmentation-of-3t-mr-images
#14
Khosro Bahrami, Islem Rekik, Feng Shi, Yaozong Gao, Dinggang Shen
The emerging era of ultra-high-field MRI using 7T MRI scanners dramatically improved sensitivity, image resolution, and tissue contrast when compared to 3T MRI scanners in examining various anatomical structures. The advantages of these high-resolution MR images include higher segmentation accuracy of MRI brain tissues. However, currently, accessibility to 7T MRI scanners remains much more limited than 3T MRI scanners due to technological and economical constraints. Hence, we propose in this work the first learning-based model that improves the segmentation of an input 3T MR image with any conventional segmentation method, through the reconstruction of a higher-quality 7T-like MR image, without actually acquiring an ultra-high-field 7T MRI...
October 2016: Medical Image Computing and Computer-assisted Intervention: MICCAI ..
https://www.readbyqxmd.com/read/28145723/ultrasmall-silica-based-bismuth-gadolinium-nanoparticles-for-dual-magnetic-resonance-computed-tomography-image-guided-radiation-therapy
#15
Alexandre Detappe, Eloise Thomas, Mark W Tibbitt, Sijumon Kunjachan, Oksana Zavidij, Nishita Parnandi, Elizaveta Reznichenko, François Lux, Olivier Tillement, Ross Berbeco
Selective killing of cancer cells while minimizing damage to healthy tissues is the goal of clinical radiation therapy. This therapeutic ratio can be improved by image-guided radiation delivery and selective radiosensitization of cancer cells. Here, we have designed and tested a novel trimodal theranostic nanoparticle made of bismuth and gadolinium for on-site radiosensitization and image contrast enhancement to improve the efficacy and accuracy of radiation therapy. We demonstrate in vivo magnetic resonance (MR), computed tomography (CT) contrast enhancement, and tumor suppression with prolonged survival in a non-small cell lung carcinoma model during clinical radiation therapy...
February 2, 2017: Nano Letters
https://www.readbyqxmd.com/read/28143574/feasibility-of-real-time-mr-thermal-dose-mapping-for-predicting-radiofrequency-ablation-outcome-in-the-myocardium-in-vivo
#16
Solenn Toupin, Pierre Bour, Matthieu Lepetit-Coiffé, Valéry Ozenne, Baudouin Denis de Senneville, Rainer Schneider, Alexis Vaussy, Arnaud Chaumeil, Hubert Cochet, Frédéric Sacher, Pierre Jaïs, Bruno Quesson
BACKGROUND: Clinical treatment of cardiac arrhythmia by radiofrequency ablation (RFA) currently lacks quantitative and precise visualization of lesion formation in the myocardium during the procedure. This study aims at evaluating thermal dose (TD) imaging obtained from real-time magnetic resonance (MR) thermometry on the heart as a relevant indicator of the thermal lesion extent. METHODS: MR temperature mapping based on the Proton Resonance Frequency Shift (PRFS) method was performed at 1...
January 25, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28132063/magnetic-resonance-imaging-guided-transplantation-of-neural-stem-cells-into-the-porcine-spinal-cord
#17
Jason J Lamanna, Lindsey N Urquia, Carl V Hurtig, Juanmarco Gutierrez, Cody Anderson, Pete Piferi, Thais Federici, John N Oshinski, Nicholas M Boulis
BACKGROUND: Cell-based therapies are a promising treatment option for traumatic, tumorigenic and degenerative diseases of the spinal cord. Transplantation into the spinal cord is achieved with intravascular, intrathecal, or direct intraparenchymal injection. The current standard for direct injection is limited by surgical invasiveness, difficulty in reinjection, and the inability to directly target anatomical or pathological landmarks. The objective of this study was to present the proof of principle for minimally invasive, percutaneous transplantation of stem cells into the spinal cord parenchyma of live minipigs under MR guidance...
January 28, 2017: Stereotactic and Functional Neurosurgery
https://www.readbyqxmd.com/read/28126217/prostate-mr-imaging-an-update
#18
REVIEW
Hiram Shaish, Samir S Taneja, Andrew B Rosenkrantz
Improvements in prostate MR imaging techniques and the introduction of MR imaging-targeted biopsies have had central roles in prostate cancer (PCa) management. The role of MR imaging has progressed from largely staging patients with biopsy-proven PCa to detecting, characterizing, and guiding the biopsy of suspected PCa. These diagnostic advances, combined with improved therapeutic interventions, have led to a more sophisticated and individually tailored approach to patients' unique PCa profile. This review discusses the MR imaging, a standardized reporting scheme, and the role of fusion-targeted prostate biopsy...
March 2017: Radiologic Clinics of North America
https://www.readbyqxmd.com/read/28123058/procalcitonin-and-midregional-proatrial-natriuretic-peptide-as-biomarkers-of-subclinical-cerebrovascular-damage-the-northern-manhattan-study
#19
Mira Katan, Yeseon Moon, Arnold von Eckardstein, Kathartina Spanaus, Janet DeRosa, Jose Gutierrez, Charles DeCarli, Clinton Wright, Ralph Sacco, Mitchell Elkind
BACKGROUND AND PURPOSE: Chronic infections and cardiac dysfunction are risk factors for stroke. We hypothesized that blood biomarkers of infection (procalcitonin) and cardiac dysfunction (midregional proatrial natriuretic peptide [MR-proANP]), previously associated with small vessel stroke and cardioembolic stroke are also associated with subclinical cerebrovascular damage, including silent brain infarcts and white matter hyperintensity volume. METHODS: The NOMAS (Northern Manhattan Study) was designed to assess risk factors for incident vascular disease in a multiethnic cohort...
January 25, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28120053/restoring-neurological-physiology-the-innovative-role-of-high-energy-mr-guided-focused-ultrasound-himrgfus-preliminary-data-from-a-new-method-of-lesioning-surgery
#20
Antonella Giugno, Rosario Maugeri, Francesca Graziano, Cesare Gagliardo, Angelo Franzini, Carlo Catalano, Massimo Midiri, Domenico Gerardo Iacopino
BACKGROUND: Tremor is a disabling condition, common to several neurodegenerative diseases. Lesioning procedures and deep brain stimulation, respectively, of the ventralis intermedius nucleus for intentional tremor, and of the subthalamic nucleus for parkinsonian resting tremor, have been introduced in clinical practice for patients refractory to medical treatment. The combination of high-energy focused ultrasound (HIFUS) with sophisticated magnetic resonance (MR) instrumentation, together with accurate knowledge of the stereotactic brain coordinates, represents a revolution in neuromodulation...
2017: Acta Neurochirurgica. Supplement
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