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Esophageal cancer nutrition

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https://www.readbyqxmd.com/read/28429247/a-review-of-the-novel-application-and-potential-adverse-effects-of-proton-pump-inhibitors
#1
REVIEW
Li-Yuan Yu, Lu-Ning Sun, Xue-Hui Zhang, Yue-Qi Li, Lei Yu, Zi-Qing-Yun Yuan, Ling Meng, Hong-Wen Zhang, Yong-Qing Wang
Proton pump inhibitors (PPIs) are known as a class of pharmaceutical agents that target H(+)/K(+)-ATPase, which is located in gastric parietal cells. PPIs are widely used in the treatment of gastric acid-related diseases including peptic ulcer disease, erosive esophagitis and gastroesophageal reflux disease, and so on. These drugs present an excellent safety profile and have become one of the most commonly prescribed drugs in primary and specialty care. Except for gastric acid-related diseases, PPIs can also be used in the treatment of Helicobacter pylori infection, viral infections, respiratory system diseases, cancer and so on...
April 20, 2017: Advances in Therapy
https://www.readbyqxmd.com/read/28391413/self-expanding-metal-stents-improve-swallowing-and-maintain-nutrition-during-neoadjuvant-therapy-for-esophageal-cancer
#2
Zachary L Smith, Jason E Gonzaga, George B Haasler, Elizabeth M Gore, Kulwinder S Dua
BACKGROUND: Patients with locally advanced esophageal cancer can have significant dysphagia. Nutritional support during neoadjuvant therapy is often delivered via nasoenteric or percutaneous feeding tubes. These approaches do not allow for per-oral feeding. AIMS: Evaluate the safety and efficacy of fully covered self-expanding metal esophageal stents for nutritional support during neoadjuvant therapy. METHODS: This was a pilot, prospective study at a single tertiary center...
April 8, 2017: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/28361298/multidisciplinary-approach-to-the-management-of-esophageal-malignancies
#3
Ranjit Joseph, Shachar Laks, Michael Meyers, Autumn J McRee
INTRODUCTION: A multidisciplinary approach in the management of complex malignancies is becoming more common, and likewise, adopting such an approach to the care of patients with locally advanced esophageal is recommended in order to optimize clinical outcomes. METHODS: In this review, we discuss both the surgical and medical oncology perspectives in the management of patients with locally advanced esophageal cancer. We review the data supporting the current standard-of-care approach, namely trimodality therapy with neoadjuvant chemo-radiotherapy followed by surgery...
March 30, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/28331260/early-enteral-nutrition-versus-parenteral-nutrition-after-resection-of-esophageal-cancer-a-retrospective-analysis
#4
Huan Ming Yu, Cheng Wu Tang, Wen Ming Feng, Qiu Qiang Chen, Yong Qiang Xu, Ying Bao
This study aimed to compare the clinical outcomes and hospitalization cost between early enteral nutrition (EEN) and parenteral nutrition (PN) after resection of esophageal cancer. A total of 79 patients with esophageal cancer who underwent surgical treatment in our hospital from July 2010 to July 2013 were enrolled in this study. They were divided into EEN group (n = 39) and PN group (n = 40) based on the nutrition support modes. The clinical factors such as time to first fecal passage, postoperative albumin infusion, differences of serum albumin value, hospital stay, systematic inflammatory response syndrome (SIRS) duration, complications, initial hospitalization cost, and mortality were retrospectively compared...
February 2017: Indian Journal of Surgery
https://www.readbyqxmd.com/read/28288055/development-of-a-core-outcome-set-for-clinical-effectiveness-trials-in-esophageal-cancer-resection-surgery
#5
Kerry N L Avery, Katy A Chalmers, Sara T Brookes, Natalie S Blencowe, Karen Coulman, Katie Whale, Chris Metcalfe, Jane M Blazeby
OBJECTIVE: Development of a core outcome set (COS) for clinical effectiveness trials in esophageal cancer resection surgery. BACKGROUND: Inconsistency and heterogeneity in outcome reporting after esophageal cancer resection surgery hampers comparison of trial results and undermines evidence synthesis. COSs provide an evidence-based approach to these challenges. METHODS: A long list of clinical and patient-reported outcomes was identified and categorized into outcome domains...
March 10, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28282392/predictive-value-of-initial-fdg-pet-features-for-treatment-response-and-survival-in-esophageal-cancer-patients-treated-with-chemo-radiation-therapy-using-a-random-forest-classifier
#6
Paul Desbordes, Su Ruan, Romain Modzelewski, Pascal Pineau, Sébastien Vauclin, Pierrick Gouel, Pierre Michel, Frédéric Di Fiore, Pierre Vera, Isabelle Gardin
PURPOSE: In oncology, texture features extracted from positron emission tomography with 18-fluorodeoxyglucose images (FDG-PET) are of increasing interest for predictive and prognostic studies, leading to several tens of features per tumor. To select the best features, the use of a random forest (RF) classifier was investigated. METHODS: Sixty-five patients with an esophageal cancer treated with a combined chemo-radiation therapy were retrospectively included. All patients underwent a pretreatment whole-body FDG-PET...
2017: PloS One
https://www.readbyqxmd.com/read/28279472/nutritional-support-in-esophagogastric-cancers
#7
REVIEW
Elliott Birnstein, Mark Schattner
Esophageal and gastric cancers are common malignancies, both in the United States and worldwide, that carry significant morbidity and mortality. Malnutrition is a common complication in patients with esophageal and gastric cancers and it portends a poor prognosis. For patients who undergo surgical therapy for these types of cancers, preoperative and postoperative nutritional optimization have been shown to improve outcomes. The support can be accomplished in different manners, including orally, enterally, or parentally...
April 2017: Surgical Oncology Clinics of North America
https://www.readbyqxmd.com/read/28244415/a-randomized-phase-2-trial-of-prophylactic-manuka-honey-for-the-reduction-of-chemoradiation-therapy-induced-esophagitis-during-the-treatment-of-lung-cancer-results-of-nrg-oncology-rtog-1012
#8
Shannon E Fogh, Snehal Deshmukh, Lawrence B Berk, Amylou C Dueck, Kevin Roof, Sherif Yacoub, Thomas Gergel, Kevin Stephans, Andreas Rimner, Albert DeNittis, John Pablo, Justin Rineer, Terence M Williams, Deborah Bruner
PURPOSE: Randomized trials have shown that honey is effective for the prevention of radiation-induced mucositis in head and neck cancer patients. Because there is no efficacious preventative for radiation esophagitis in lung cancer patients, this trial compared liquid honey, honey lozenges, and standard supportive care for radiation esophagitis. METHODS: The patients were stratified by percentage of esophagus receiving specific radiation dose (V60 Gy esophagus <30% or ≥30%) and were then randomized between supportive care, 10 mL of liquid manuka honey 4 times a day, and 2 lozenges (10 mL of dehydrated manuka honey) 4 times a day during concurrent chemotherapy and radiation therapy...
March 15, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28242319/white-paper-aga-power-practice-guide-on-obesity-and%C3%A2-weight-management-education-and-resources
#9
REVIEW
Andres Acosta, Sarah Streett, Mathew D Kroh, Lawrence J Cheskin, Katherine H Saunders, Marina Kurian, Marsha Schofield, Sarah E Barlow, Louis Aronne
The epidemic of obesity continues at alarming rates, with a high burden to our economy and society. The American Gastroenterological Association understands the importance of embracing obesity as a chronic, relapsing disease and supports a multidisciplinary approach to the management of obesity. Because gastrointestinal disorders resulting from obesity are more frequent and often present sooner than type 2 diabetes mellitus and cardiovascular disease, gastroenterologists have an opportunity to address obesity and provide an effective therapy early...
May 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28226350/-value-of-endoscopy-application-in-the-management-of-complications-after-radical-gastrectomy-for-gastric-cancer
#10
Yiqun Zhang, Pinghong Zhou
Endoscopy plays an important role in the diagnosis and treatment of postoperative complications of gastric cancer. Endoscopic intervention can avoid the second operation and has attracted wide attention. Early gastric anastomotic bleeding after gastrectomy is the most common. With the development of technology, emergency endoscopy and endoscopic hemostasis provide a new treatment approach. According to the specific circumstances, endoscopists can choose metal clamp to stop bleeding, electrocoagulation hemostasis, local injection of epinephrine or sclerotherapy agents, and spraying specific hemostatic agents...
February 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28192107/gastrointestinal-complications-of-obesity
#11
Michael Camilleri, Harmeet Malhi, Andres Acosta
Obesity usually is associated with morbidity related to diabetes mellitus and cardiovascular diseases. However, there are many gastrointestinal and hepatic diseases for which obesity is the direct cause (eg, nonalcoholic fatty liver disease) or is a significant risk factor, such as reflux esophagitis and gallstones. When obesity is a risk factor, it may interact with other mechanisms and result in earlier presentation or complicated diseases. There are increased odds ratios or relative risks of several gastrointestinal complications of obesity: gastroesophageal reflux disease, erosive esophagitis, Barrett's esophagus, esophageal adenocarcinoma, erosive gastritis, gastric cancer, diarrhea, colonic diverticular disease, polyps, cancer, liver disease including nonalcoholic fatty liver disease, cirrhosis, hepatocellular carcinoma, gallstones, acute pancreatitis, and pancreatic cancer...
February 10, 2017: Gastroenterology
https://www.readbyqxmd.com/read/28190657/cross-sectional-analysis-of-biobank-japan-clinical-data-a-large-cohort-of-200-000-patients-with-47-common-diseases
#12
Makoto Hirata, Yoichiro Kamatani, Akiko Nagai, Yutaka Kiyohara, Toshiharu Ninomiya, Akiko Tamakoshi, Zentaro Yamagata, Michiaki Kubo, Kaori Muto, Taisei Mushiroda, Yoshinori Murakami, Koichiro Yuji, Yoichi Furukawa, Hitoshi Zembutsu, Toshihiro Tanaka, Yozo Ohnishi, Yusuke Nakamura, Koichi Matsuda
BACKGROUND: To implement personalized medicine, we established a large-scale patient cohort, BioBank Japan, in 2003. BioBank Japan contains DNA, serum, and clinical information derived from approximately 200,000 patients with 47 diseases. Serum and clinical information were collected annually until 2012. METHODS: We analyzed clinical information of participants at enrollment, including age, sex, body mass index, hypertension, and smoking and drinking status, across 47 diseases, and compared the results with the Japanese database on Patient Survey and National Health and Nutrition Survey...
March 2017: Journal of Epidemiology
https://www.readbyqxmd.com/read/28156663/evaluation-of-combined-argon-plasma-coagulation-and-savary-bougienage-for-the-relief-of-dysphagia-of-esophageal-squamous-cancer-patients-in-the-end-of-life
#13
Caihong Dong, Tanyou Shan, Xiaozhi Yuan, Shuoguo Li, Xuezhen Ding, Shegan Gao
214 Background: To relieve the dysphagia is a critical treatment for advanced esophageal cancer patients' palliative care in their end-of-life. The ideal way is to satisfy both the patient's nutrition supplement and self-taste. Although several endoscopic dilation techniques have been reported, the high incidence of dysphagia quickly relapsing remains. The aim of this study was to compare the effect of Argon Plasma Coagulation (APC) combined with Savary bougienage (SB) and SB alone for the relief of dysphagia of esophageal squamous cancer in the end-of-life...
October 9, 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28152219/effect-of-prophylactic-percutaneous-endoscopic-gastrostomy-tube-on-swallowing-in-advanced-head-and-neck-cancer-a-randomized-controlled-study
#14
Lars Axelsson, Ewa Silander, Jan Nyman, Mogens Bove, Leif Johansson, Eva Hammerlid
BACKGROUND: Dysphagia is common in head and neck cancer. A percutaneous endoscopic gastrostomy (PEG) tube is used to facilitate nutrition; however, some retrospective studies have indicated that the PEG tube causes dysphagia. METHODS: A randomized study of patients with head and neck cancer was conducted with up to 10 years of follow-up. Patients were randomized to either the prophylactic PEG tube group (study group) or the common clinical nutritional support group (control group)...
February 2, 2017: Head & Neck
https://www.readbyqxmd.com/read/28138759/preoperative-controlling-nutritional-status-conut-is-useful-to-estimate-the-prognosis-after-esophagectomy-for-esophageal-cancer
#15
Naoya Yoshida, Kazuto Harada, Yoshifumi Baba, Keisuke Kosumi, Masaaki Iwatsuki, Koichi Kinoshita, Kenichi Nakamura, Yasuo Sakamoto, Yuji Miyamoto, Ryuichi Karashima, Kosuke Mima, Hiroshi Sawayama, Mayuko Ohuchi, Akira Chikamoto, Yu Imamura, Masayuki Watanabe, Hideo Baba
PURPOSE: The aim of this study is to confirm the predictive value of controlling nutritional status (CONUT), as a postoperative prognostic marker for esophageal cancer patients undergoing esophagectomy. METHODS: We retrospectively analyzed 373 patients who underwent three-incision esophagectomy with 2- or 3-field lymphadenectomy for esophageal cancer between April 2005 and March 2016. The patients were divided into three groups based on the degree of preoperative malnutrition as assessed by CONUT: normal, light malnutrition, and moderate or severe malnutrition...
March 2017: Langenbeck's Archives of Surgery
https://www.readbyqxmd.com/read/28138387/peripheral-vein-infusions-of-amino-acids-facilitate-recovery-after-esophagectomy-for-esophageal-cancer-retrospective-cohort-analysis
#16
Masafumi Konosu, Takeshi Iwaya, Yusuke Kimura, Yuji Akiyama, Yoshihiro Shioi, Fumitaka Endo, Hiroyuki Nitta, Koki Otsuka, Keisuke Koeda, Akira Sasaki
BACKGROUND: To investigate the efficacy of amino acid administration via peripheral veins in addition to conventional enteral feeding following esophagectomy. MATERIALS AND METHODS: Retrospective analysis of data pertaining to 33 patients with esophageal cancer who underwent radical esophagectomy and satisfied the required nutrition control. Patients were divided into the amino acid group (n = 17) and control group (n = 16). Primary outcomes were albumin (Alb) and prealbumin (PreAlb) levels, urinary 3-methylhistidine/creatinine (3-MeHis/Cre) ratios, nitrogen balance, and weight; postoperative complications were noted as secondary outcomes...
February 2017: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/28133202/-cr-of-all-target-lesions-in-a-patient-with-metastatic-esophageal-cancer-and-generalized-weakness-treated-with-systemic-chemotherapy-after-nutritional-support
#17
Shigeru Fujisaki, Motoi Takashina, Ryouichi Tomita, Kenichi Sakurai, Tadatoshi Takayama
We report here a case of CR of all target lesions in a patient with esophageal cancer with multiple metastases treated with systemic chemotherapy after nutritionalsupport. A 75-year-old man was referred to our hospital with a diagnosis of multiple- metastatic esophagealcancer in June 2014. He showed generalized weakness with poor dietary intake, and he was initially admitted for nutritional support by parenteral nutrition. Biopsy specimens revealed mixed squamous- and adenocarcinoma: MtLtUtAeG, 13 cm, type 2, cT3, IM1-St, cN3, cM1(liver, lungs, and stomach), cStage IV b esophagealcarcinoma...
November 2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/28130623/clinical-outcomes-and-evaluation-of-laparoscopic-proximal-gastrectomy-with-double-flap-technique-for-early-gastric-cancer-in-the-upper-third-of-the-stomach
#18
Masaru Hayami, Naoki Hiki, Souya Nunobe, Shinji Mine, Manabu Ohashi, Koshi Kumagai, Satoshi Ida, Masayuki Watanabe, Takeshi Sano, Toshiharu Yamaguchi
BACKGROUND: A novel double-flap esophagogastrostomy technique developed to prevent reflux after proximal gastrectomy was applied to laparoscopic proximal gastrectomy (LPG), and the clinical outcomes of this technique (LPG-DFT) were evaluated and compared to those of laparoscopic total gastrectomy (LTG). METHODS: This retrospective study of 90 patients with early gastric cancer (EGC) in the upper third of the stomach compared surgical outcomes, postoperative endoscopic findings, and nutritional status between two procedure groups, LPG-DFT (n = 43) and LTG (n = 47)...
January 27, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/28105355/evaluation-of-prognostic-markers-for-patients-with-curatively-resected-thoracic-esophageal-squamous-cell-carcinomas
#19
Masahide Ikeguchi, Yusuke Kouno, Kyoichi Kihara, Kazunori Suzuki, Kanenori Endo, Seiichi Nakamura, Takashi Sawada, Tetsu Shimizu, Tomoyuki Matsunaga, Yoji Fukumoto, Hiroaki Saito
The Glasgow Prognostic Score (GPS), neutrophil/lymphocyte ratio (NLR) and prognostic nutritional index (PNI) are prognostic parameters for malignancies. Additionally, serum squamous cell carcinoma antigen (SCC-Ag) and cytokeratin 19 fragments (CYFRA 21-1) are tumor markers for squamous cell carcinoma. In the present study, the prognostic importance of these markers in patients with resectable thoracic esophageal cancer was investigated. In this retrospective study, 84 enrolled patients diagnosed with resectable clinical stage I-III thoracic esophageal squamous cell carcinomas (ESCCs) underwent thoracic esophageal resection and three-field lymph node dissection at Tottori University Hospital between January 2007 and December 2013...
December 2016: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/28077159/concurrent-chemoradiotherapy-combined-with-enteral-nutrition-support-a-radical-treatment-strategy-for-esophageal-squamous-cell-carcinoma-patients-with-malignant-fistulae
#20
Li Ma, Guang-Yu Luo, Yu-Feng Ren, Bo Qiu, Hong Yang, Chun-Xia Xie, Song-Ran Liu, Shi-Liang Liu, Zhao-Lin Chen, Qun Li, Jian-Hua Fu, Meng-Zhong Liu, Yong-Hong Hu, Wen-Feng Ye, Hui Liu
BACKGROUND: Concurrent chemoradiotherapy (CCRT) significantly increases the survival rate of esophageal squamous cell carcinoma (ESCC) patients with malignant fistulae. Recent clinical evidence has shown the benefits of enteral nutrition for malnourished cancer patients. In this study, we aimed to validate that, with the support of enteral nutrition, ESCC patients who develop malignant fistulae might be able to complete CCRT and achieve long-term survival. METHODS: We reviewed the medical records of 652 patients with ESCC who received definitive CCRT at Sun Yat-sen University Cancer Center between January 2010 and December 2012...
January 11, 2017: Chinese Journal of Cancer
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