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https://www.readbyqxmd.com/read/28920558/i-shouldn-t-talk-of-medicine-only-biomedical-and-religious-frameworks-for-understanding-antiretroviral-therapies-their-invention-and-their-effects
#1
Angela Kelly-Hanku, Peter Aggleton, Patti Shih
Medical pluralism offers a long-standing means of analysing the different ways in which health and illness can be interpreted and responded to. It is not unusual for multiple health systems and meanings to co-exist at any one moment in time, offering different ways of understanding and responding to illness and disease. In addition to biomedical frameworks, religious beliefs offer another important means of facilitating healing. Based on qualitative interviews with 36 people living with HIV on antiretroviral therapies (ART) in Papua New Guinea (PNG), this paper examines the ways in which people bring together and synthesise religious and biomedical therapeutic approaches to the treatment and management of HIV...
September 16, 2017: Global Public Health
https://www.readbyqxmd.com/read/28912245/a-neolithic-expansion-but-strong-genetic-structure-in-the-independent-history-of-new-guinea
#2
Anders Bergström, Stephen J Oppenheimer, Alexander J Mentzer, Kathryn Auckland, Kathryn Robson, Robert Attenborough, Michael P Alpers, George Koki, William Pomat, Peter Siba, Yali Xue, Manjinder S Sandhu, Chris Tyler-Smith
New Guinea shows human occupation since ~50 thousand years ago (ka), independent adoption of plant cultivation ~10 ka, and great cultural and linguistic diversity today. We performed genome-wide single-nucleotide polymorphism genotyping on 381 individuals from 85 language groups in Papua New Guinea and find a sharp divide originating 10 to 20 ka between lowland and highland groups and a lack of non-New Guinean admixture in the latter. All highlanders share ancestry within the last 10 thousand years, with major population growth in the same period, suggesting population structure was reshaped following the Neolithic lifestyle transition...
September 15, 2017: Science
https://www.readbyqxmd.com/read/28912225/papua-new-guinea-s-genetic-diversity-withstood-farming
#3
Ann Gibbons
No abstract text is available yet for this article.
September 15, 2017: Science
https://www.readbyqxmd.com/read/28904144/low-recruitment-due-to-altered-settlement-substrata-as-primary-constraint-for-coral-communities-under-ocean-acidification
#4
Katharina E Fabricius, Sam H C Noonan, David Abrego, Lindsay Harrington, Glenn De'ath
The future of coral reefs under increasing CO2 depends on their capacity to recover from disturbances. To predict the recovery potential of coral communities that are fully acclimatized to elevated CO2, we compared the relative success of coral recruitment and later life stages at two volcanic CO2 seeps and adjacent control sites in Papua New Guinea. Our field experiments showed that the effects of ocean acidification (OA) on coral recruitment rates were up to an order of magnitude greater than the effects on the survival and growth of established corals...
September 13, 2017: Proceedings. Biological Sciences
https://www.readbyqxmd.com/read/28903875/risk-assessment-of-the-entry-of-canine-rabies-into-papua-new-guinea-via-sea-and-land-routes
#5
Victoria J Brookes, Andy Keponge-Yombo, David Thomson, Michael P Ward
Canine-rabies is endemic in parts of Indonesia and continues to spread eastwards through the Indonesian archipelago. Papua New Guinea (PNG) has a land border with Papua Province, Indonesia, as well as logging and fishing industry connections throughout Asia. PNG has a Human Development Index of 0.505; therefore, an incursion of canine-rabies could have devastating impacts on human (7.5 million) and animal populations. Given the known difficulties of rabies elimination in resource-scarce environments, an incursion of rabies into PNG would also likely compromise the campaign for global elimination of rabies...
September 15, 2017: Preventive Veterinary Medicine
https://www.readbyqxmd.com/read/28886702/safety-and-effectiveness-of-oral-misoprostol-for-induction-of-labour-in-a-resource-limited-setting-a-dose-escalation-study
#6
Marilyn Morris, John W Bolnga, Ovoi Verave, Jimmy Aipit, Allanie Rero, Moses Laman
BACKGROUND: Oral misoprostol as an induction of labour (IOL) agent is rapidly gaining popularity in resource-limited settings because it is cheap, stable at ambient temperatures, and logistically easier to administer compared to dinoprostone and oxytocin. We aim to investigate the safety and effectiveness of a regimen of oral misoprostol in Papua New Guinean women undergoing IOL. METHODS: As part of a prospective dose escalation study conducted at Modilon Hospital in Papua New Guinea, women with a singleton pregnancy in cephalic presentation and an unfavourable cervix who gave written informed consent were administered oral misoprostol, commencing at 25mcg once every 2 h for 4 doses and increased to 50mcg once every 2 h for 8 doses within 24 h...
September 8, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28873087/women-s-and-men-s-reports-of-past-year-prevalence-of-intimate-partner-violence-and-rape-and-women-s-risk-factors-for-intimate-partner-violence-a-multicountry-cross-sectional-study-in-asia-and-the-pacific
#7
Rachel Jewkes, Emma Fulu, Ruchira Tabassam Naved, Esnat Chirwa, Kristin Dunkle, Regine Haardörfer, Claudia Garcia-Moreno
BACKGROUND: Understanding the past-year prevalence of male-perpetrated intimate partner violence (IPV) and risk factors is essential for building evidence-based prevention and monitoring progress to Sustainable Development Goal (SDG) 5.2, but so far, population-based research on this remains very limited. The objective of this study is to compare the population prevalence rates of past-year male-perpetrated IPV and nonpartner rape from women's and men's reports across 4 countries in Asia and the Pacific...
September 2017: PLoS Medicine
https://www.readbyqxmd.com/read/28863338/perceptions-of-incentives-offered-in-a-community-based-malaria-diagnosis-and-treatment-program-in-the-highlands-of-papua-new-guinea
#8
Camilla Burkot, Laura Naidi, Liesel Seehofer, Kevin Miles
What motivates community-based health workers to provide care in rural and remote areas, often on a voluntary or casual basis, is a key question for program managers and public health officials. This paper examines how a range of incentives offered as part of the Marasin Stoa Kipa program, a community-based malaria diagnosis and treatment program that has been implemented since 2007 within a major oil and gas development area in Papua New Guinea, are perceived and critiqued by community-based health workers...
August 23, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28862132/the-complex-relationship-of-exposure-to-new-plasmodium-infections-and-incidence-of-clinical-malaria-in-papua-new-guinea
#9
Natalie E Hofmann, Stephan Karl, Rahel Wampfler, Benson Kiniboro, Albina Teliki, Jonah Iga, Andreea Waltmann, Inoni Betuela, Ingrid Felger, Leanne J Robinson, Ivo Mueller
The molecular force of blood-stage infection (molFOB) is a quantitative surrogate metric for malaria transmission at population level and for exposure at individual level. Relationships between molFOB, parasite prevalence and clinical incidence were assessed in a treatment-to-reinfection cohort, where P.vivax (Pv) hypnozoites were eliminated in half the children by primaquine (PQ). Discounting relapses, children acquired equal numbers of new P. falciparum (Pf) and Pv blood-stage infections/year (Pf-molFOB=0-18, Pv-molFOB=0-23) resulting in comparable spatial and temporal patterns in incidence and prevalence of infections...
September 1, 2017: ELife
https://www.readbyqxmd.com/read/28859651/video-based-feedback-as-a-method-for-training-rural-healthcare-workers-to-manage-medical-emergencies-a-pilot-study
#10
Zainab Oseni, Hla Hla Than, Edyta Kolakowska, Lauren Chalmers, Borimas Hanboonkunupakarn, Rose McGready
BACKGROUND: Video-based feedback has been shown to aid knowledge retention, skills learning and improve team functionality. We explored the use of video-based feedback and low fidelity simulation for training rural healthcare workers along the Thailand-Myanmar border and Papua New Guinea (PNG) to manage medical emergencies effectively. METHODS: Twenty-four study participants were recruited from three Shoklo Malaria Research Unit clinics along the Thailand-Myanmar border and eight participants from Kudjip Nazarene Hospital, PNG...
August 31, 2017: BMC Medical Education
https://www.readbyqxmd.com/read/28852590/population-structure-of-bathymodiolus-manusensis-a-deep-sea-hydrothermal-vent-dependent-mussel-from-manus-basin-papua-new-guinea
#11
Andrew D Thaler, William Saleu, Jens Carlsson, Thomas F Schultz, Cindy L Van Dover
Deep-sea hydrothermal vents in the western Pacific are increasingly being assessed for their potential mineral wealth. To anticipate the potential impacts on biodiversity and connectivity among populations at these vents, environmental baselines need to be established. Bathymodiolus manusensis is a deep-sea mussel found in close association with hydrothermal vents in Manus Basin, Papua New Guinea. Using multiple genetic markers (cytochrome C-oxidase subunit-1 sequencing and eight microsatellite markers), we examined population structure at two sites in Manus Basin separated by 40 km and near a potential mining prospect, where the species has not been observed...
2017: PeerJ
https://www.readbyqxmd.com/read/28838658/prion-protein-and-genetic-susceptibility-to-diseases-caused-by-its-misfolding
#12
George A Carlson
Early genetic studies on scrapie, an infectious neurodegenerative disease of sheep that was adapted to mice, provided evidence in support of the hypothesis that the agent was a slow virus with a nucleic acid genome independent of the host. Particularly compelling support for an independent genome came from the existence of strains of scrapie agent, some of which were true breeding, while others appeared to mutate under selective pressure. Kuru, a neurodegenerative disease in the remote highlands of Papua New Guinea, had pathological changes similar to those in scrapie and also proved to be transmissible...
2017: Progress in Molecular Biology and Translational Science
https://www.readbyqxmd.com/read/28833064/patterns-of-protective-associations-differ-for-antibodies-to-p-falciparum-infected-erythrocytes-and-merozoites-in-immunity-against-malaria-in-children
#13
Jo-Anne Chan, Danielle I Stanisic, Michael F Duffy, Leanne J Robinson, Enmoore Lin, James W Kazura, Christopher L King, Peter M Siba, Freya Ji Fowkes, Ivo Mueller, James G Beeson
Acquired antibodies play an important role in immunity to P. falciparum malaria and are typically directed towards surface antigens expressed by merozoites and infected erythrocytes (IEs). The importance of specific IE surface antigens as immune targets remains unclear. We evaluated antibodies and protective associations in two cohorts of children in Papua New Guinea. We used genetically-modified P. falciparum to evaluate the importance of PfEMP1 and a P. falciparum isolate with a virulent phenotype. Our findings suggested that PfEMP1 was the dominant target of antibodies to the IE surface, including functional antibodies that promoted opsonic phagocytosis by monocytes...
August 20, 2017: European Journal of Immunology
https://www.readbyqxmd.com/read/28812625/larval-fish-dispersal-in-a-coral-reef-seascape
#14
Glenn R Almany, Serge Planes, Simon R Thorrold, Michael L Berumen, Michael Bode, Pablo Saenz-Agudelo, Mary C Bonin, Ashley J Frisch, Hugo B Harrison, Vanessa Messmer, Gerrit B Nanninga, Mark A Priest, Maya Srinivasan, Tane Sinclair-Taylor, David H Williamson, Geoffrey P Jones
Larval dispersal is a critical yet enigmatic process in the persistence and productivity of marine metapopulations. Empirical data on larval dispersal remain scarce, hindering the use of spatial management tools in efforts to sustain ocean biodiversity and fisheries. Here we document dispersal among subpopulations of clownfish (Amphiprion percula) and butterflyfish (Chaetodon vagabundus) from eight sites across a large seascape (10,000 km(2)) in Papua New Guinea across 2 years. Dispersal of clownfish was consistent between years, with mean observed dispersal distances of 15 km and 10 km in 2009 and 2011, respectively...
May 8, 2017: Nature ecology & evolution
https://www.readbyqxmd.com/read/28796774/an-in-country-model-of-workforce-support-for-trained-mid-level-eye-care-workers-in-papua-new-guinea-and-pacific-islands
#15
Julie Brûlé, Benoit Tousignant, Graeme Nicholls, Matthew G Pearce
To alleviate the significant burden of vision impairment and blindness in low-resource settings, addressing the shortage in human resources in eye care is one of the fundamental strategies. With its postgraduate training programmes, The Fred Hollows Foundation New Zealand (FHFNZ) aims to increase workforce capacity in the Pacific Island countries and territories and Papua New Guinea. This paper presents an in-country model to offer support to graduates, an essential element to retain them in the workforce and ensure they are able to perform the tasks they were trained to do...
August 11, 2017: New Zealand Medical Journal
https://www.readbyqxmd.com/read/28792240/coping-with-drought-in-rural-papua-new-guinea-a-western-highlands-case-study
#16
Pauline Rutendo Gwatirisa, Barbara Pamphilon, Katja Mikhailovich
The short- and long-term effects of climate change on Papua New Guinea's agricultural sector have generated significant debate in recent times. Current literature demonstrates that different population groups have differing levels of vulnerability and resilience to the flow-on effects of climate change, particularly drought. Yet different schools of thought on the country's food security and effects on livelihoods persist. This article draws on evidence from research conducted in the Western Highlands of Papua New Guinea as part of a bigger economic empowerment project to illustrate the vulnerabilities of one community of rural semisubsistence farmers to drought-induced food insecurity...
August 9, 2017: Ecology of Food and Nutrition
https://www.readbyqxmd.com/read/28750615/implications-of-male-circumcision-for-women-in-papua-new-guinea-a-transformational-grounded-theory-study
#17
Michelle Redman-MacLaren, Jane Mills, Rachael Tommbe, David MacLaren, Rick Speare, William J H McBride
BACKGROUND: Male circumcision reduces the risk of female-to-male transmission of human immunodeficiency virus (HIV) and is being explored for HIV prevention in Papua New Guinea (PNG). PNG has a concentrated HIV epidemic which is largely heterosexually transmitted. There are a diverse range of male circumcision and penile modification practices across PNG. Exploring the implications of male circumcision for women in PNG is important to inform evidence-based health policy that will result in positive, intended consequences...
July 27, 2017: BMC Women's Health
https://www.readbyqxmd.com/read/28743668/a-new-haplotype-of-the-coconut-rhinoceros-beetle-oryctes-rhinoceros-has-escaped-biological-control-by-oryctes-rhinoceros-nudivirus-and-is-invading-pacific-islands
#18
Sean D G Marshall, Aubrey Moore, Maclean Vaqalo, Alasdair Noble, Trevor A Jackson
The coconut rhinoceros beetle (CRB; Oryctes rhinoceros) is a major pest of coconut and oil palm, but the discovery and release of Oryctes rhinoceros nudivirus (OrNV) in the 1960s and 70s suppressed the pest such that no new invasions of uninfested islands by CRB were reported for over 30years after implementation of the biocontrol programme. Surprisingly, a highly damaging outbreak was reported from Guam (2007), which could not be controlled by OrNV. Subsequently, new invasions have been reported from Port Moresby, Papua New Guinea (2009); O'ahu, Hawai'i (2013); and Honiara, Solomon Islands (2015)...
October 2017: Journal of Invertebrate Pathology
https://www.readbyqxmd.com/read/28727800/demographic-disequilibrium-in-living-nautiloids-nautilus-and-allonautilus-canary-in-the-coal-mines
#19
W Bruce Saunders, Emily Greenfest-Allen, Peter D Ward
Averaged demographic data from previously unfished populations of Nautilus and Allonautilus (Cephalopoda) provide a baseline to determine if a population is undisturbed and in "equilibrium" or is in "disequilibrium" as a result of fishery pressure. Data are available for previously undisturbed local nautiloid populations in Papua New Guinea, Australia, Indonesia, Fiji, Palau, American Samoa, New Caledonia and Vanuatu (total n = 2,669 live-caught, tagged and released animals). The data show that unfished populations average ~75% males and ~74% mature animals...
2017: PloS One
https://www.readbyqxmd.com/read/28727232/functional-genomic-analysis-of-corals-from-natural-co2-seeps-reveals-core-molecular-responses-involved-in-acclimatization-to-ocean-acidification
#20
C D Kenkel, A Moya, J Strahl, C Humphrey, L K Bay
Little is known about the potential for acclimatization or adaptation of corals to ocean acidification and even less about the molecular mechanisms underpinning these processes. Here we examine global gene expression patterns in corals and their intracellular algal symbionts from two replicate population pairs in Papua New Guinea that have undergone long-term acclimatization to natural variation in pCO2 . In the coral host, only 61 genes were differentially expressed in response to pCO2 environment, but the pattern of change was highly consistent between replicate populations, likely reflecting the core expression homeostasis response to ocean acidification...
July 20, 2017: Global Change Biology
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